PH12018050517A1 - Ribavirin pharmaceutical composition for injection, its preparation method and application thereof - Google Patents
Ribavirin pharmaceutical composition for injection, its preparation method and application thereofInfo
- Publication number
- PH12018050517A1 PH12018050517A1 PH12018050517A PH12018050517A PH12018050517A1 PH 12018050517 A1 PH12018050517 A1 PH 12018050517A1 PH 12018050517 A PH12018050517 A PH 12018050517A PH 12018050517 A PH12018050517 A PH 12018050517A PH 12018050517 A1 PH12018050517 A1 PH 12018050517A1
- Authority
- PH
- Philippines
- Prior art keywords
- injection
- ribavirin
- liquid
- preparation
- add
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention particularly relates to ribavirin pharmaceutical composition for injection, its preparation method and application thereof. The raw materials of ribavirin injection include: ribavirin, activated carbon and water for injection; the preparation steps of ribavirin injection are as follows: (1) will be called according to the prescription the amount of related raw materials, (2) for liquid-concentration, first into the concentrated tank to add water for injection, then add ribavirin and stir to dissolve, then add activated carbon, and heat to boil for 15 min; (3) with titanium filter Recirculating and removing carbon from the liquid; (4) Performing the dosing of the solution, adding the water for injection to the filtered liquid to the configured amount, adjusting the pH of the solution to a suitable range, and performing the relevant quality indicators of the liquid Testing; (5) conducting the liquid medicine for testing the qualified liquid; (6) entering the semi-finished product after the potting sterilize. The ribavirin injection prepared by the preparation method of the invention. has the advantages of high purity, less impurities, single component, good stability and good drug effect.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810631119.7A CN108434095A (en) | 2018-06-19 | 2018-06-19 | A kind of ribavirin injection pharmaceutical composition and its preparation method and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12018050517A1 true PH12018050517A1 (en) | 2020-05-04 |
Family
ID=63206384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH12018050517A PH12018050517A1 (en) | 2018-06-19 | 2018-11-27 | Ribavirin pharmaceutical composition for injection, its preparation method and application thereof |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN108434095A (en) |
| PH (1) | PH12018050517A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114955031B (en) * | 2022-05-27 | 2023-09-22 | 山东希尔康泰药业有限公司 | Sterile preparation system for diclofenac sodium lidocaine hydrochloride injection |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101884612A (en) * | 2010-06-29 | 2010-11-17 | 上海华中药业有限公司 | Preparation method of large volume ribavirin injection |
| CN102366401A (en) * | 2011-09-28 | 2012-03-07 | 河南辅仁怀庆堂制药有限公司 | Ribavirin injection and preparation process thereof |
| CN104000778A (en) * | 2014-06-18 | 2014-08-27 | 海南通用康力制药有限公司 | Ribavirin injection and preparing method thereof |
| CN105232477B (en) * | 2015-08-25 | 2018-08-17 | 浙江尖峰药业有限公司 | A kind of injection Ribavirin and preparation method thereof |
| CN105301127B (en) * | 2015-10-13 | 2018-09-18 | 康普药业股份有限公司 | A kind of Ribavirin pharmaceutical composition and its related substance detecting method |
-
2018
- 2018-06-19 CN CN201810631119.7A patent/CN108434095A/en active Pending
- 2018-11-27 PH PH12018050517A patent/PH12018050517A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN108434095A (en) | 2018-08-24 |
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