CN104623633A - 用于治疗或预防心力衰竭的神经调节蛋白或其亚序列的治疗性施剂 - Google Patents
用于治疗或预防心力衰竭的神经调节蛋白或其亚序列的治疗性施剂 Download PDFInfo
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1883—Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| CN201710109733.2A Expired - Fee Related CN107019794B (zh) | 2008-07-17 | 2009-07-17 | 用于治疗或预防心力衰竭的神经调节蛋白或其亚序列的治疗性施剂 |
| CN2009801360798A Pending CN102159236A (zh) | 2008-07-17 | 2009-07-17 | 用于治疗或预防心力衰竭的神经调节蛋白或其亚序列的治疗性施剂 |
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| CN2009801360798A Pending CN102159236A (zh) | 2008-07-17 | 2009-07-17 | 用于治疗或预防心力衰竭的神经调节蛋白或其亚序列的治疗性施剂 |
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| Country | Link |
|---|---|
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| EP (3) | EP3632459A1 (enExample) |
| JP (5) | JP5797112B2 (enExample) |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108778315A (zh) * | 2016-04-19 | 2018-11-09 | 莱布尼茨研究所-针对老化研究(弗里茨利普曼研究所) | 用于治疗和/或预防神经系统肿瘤的神经调节素 |
| CN110835368A (zh) * | 2018-08-15 | 2020-02-25 | 上海泽生科技开发股份有限公司 | 神经调节蛋白多肽片段及其用途 |
| WO2021052277A1 (zh) * | 2019-09-16 | 2021-03-25 | 上海泽生科技开发股份有限公司 | 重组人神经调节蛋白衍生物及其用途 |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3632459A1 (en) * | 2008-07-17 | 2020-04-08 | Acorda Therapeutics, Inc. | Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure |
| EP3777878A1 (en) | 2008-08-15 | 2021-02-17 | Acorda Therapeutics, Inc. | Compositions and methods for treatment during non-acute periods following cns neurological injury |
| EP2808339B1 (en) | 2008-11-28 | 2017-02-15 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Neuregulin peptides and their use |
| PL2488194T3 (pl) | 2009-10-14 | 2016-11-30 | Zastosowanie neureguliny do leczenia uszkodzenia nerwu jamistego | |
| WO2013053076A1 (en) | 2011-10-10 | 2013-04-18 | Zensun （Shanghai）Science & Technology Limited | Compositions and methods for treating heart failure |
| EP2830645B1 (en) * | 2012-03-30 | 2017-08-30 | Acorda Therapeutics, Inc. | Neuregulin for use in treating peripheral nerve injury |
| AU2014225534A1 (en) * | 2013-03-06 | 2015-09-24 | Acorda Therapeutics, Inc. | Therapeutic dosing of a neuregulin or a fragment thereof for treatment or prophylaxis of heart failure |
| BR112015029293A2 (pt) | 2013-05-22 | 2018-04-24 | Zensun Shanghai Science & Tech Ltd | método e kit para prevenir, tratar ou retardar uma doença ou distúrbio cardiovascular em um mamífero |
| CN104758922A (zh) | 2014-01-03 | 2015-07-08 | 上海泽生科技开发有限公司 | 纽兰格林制剂的配方 |
| CN105561298A (zh) * | 2014-10-17 | 2016-05-11 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物 |
| US20180296642A1 (en) | 2015-09-25 | 2018-10-18 | Douglas B. Sawyer | Methods for treating cardiac injury |
| AR121035A1 (es) | 2019-04-01 | 2022-04-13 | Lilly Co Eli | Compuestos de neuregulina-4 y métodos de uso |
| US20250241989A1 (en) * | 2021-10-22 | 2025-07-31 | The Research Institute At Nationwide Children's Hospital | Neuregulin for Protection Against Respiratory Viral Infection and Post-Viral Disease |
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| US6635249B1 (en) * | 1999-04-23 | 2003-10-21 | Cenes Pharmaceuticals, Inc. | Methods for treating congestive heart failure |
| CN1138785C (zh) * | 1999-06-04 | 2004-02-18 | 周明东 | 生长因子神经调节蛋白及其类似物的新应用 |
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| US5716930A (en) | 1991-04-10 | 1998-02-10 | Ludwig Institute For Cancer Research | Glial growth factors |
| US7115554B1 (en) * | 1993-05-06 | 2006-10-03 | Acorda Therapeutics, Inc. | Methods of increasing myotube formation or survival or muscle cell mitogenesis differentiation or survival using neuregulin GGF III |
| US5530109A (en) | 1991-04-10 | 1996-06-25 | Ludwig Institute For Cancer Research | DNA encoding glial mitogenic factors |
| US6087323A (en) | 1992-04-03 | 2000-07-11 | Cambridge Neuroscience, Inc. | Use of neuregulins as modulators of cellular communication |
| US7037888B1 (en) | 1992-04-03 | 2006-05-02 | Acorda Therapeutics, Inc. | Methods for treating muscle diseases and disorders |
| US5811098A (en) * | 1992-11-24 | 1998-09-22 | Bristol-Myers Squibb Company | Antibodies to HER4, human receptor tyrosine kinase |
| US5912326A (en) | 1995-09-08 | 1999-06-15 | President And Fellows Of Harvard College | Cerebellum-derived growth factors |
| US6136558A (en) * | 1997-02-10 | 2000-10-24 | Genentech, Inc. | Heregulin variants |
| US6051401A (en) | 1998-07-28 | 2000-04-18 | Bayer Corporation | Methods and constructs for protein expression |
| HK1040363B (en) | 1998-09-25 | 2007-01-26 | Cubist Pharmaceuticals Llc | Use of daptomycin |
| AUPP785098A0 (en) * | 1998-12-21 | 1999-01-21 | Victor Chang Cardiac Research Institute, The | Treatment of heart disease |
| AU1916301A (en) | 1999-11-12 | 2001-06-06 | Children's Medical Center Corporation | Methods for administration of therapeutic agents on an antiangiogenic schedule |
| EP2357004B1 (en) | 2000-05-23 | 2016-10-12 | CeNeS Pharmaceuticals, Inc. | NRG-2 nucleic acid molecules, polypeptides and diagnostic and therapeutical methods |
| CU23157A1 (es) * | 2001-01-03 | 2006-07-18 | Ct Ingenieria Genetica Biotech | COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL |
| AU2003210549A1 (en) | 2002-01-18 | 2003-09-02 | Chiron Corporation | Combination il-2/anti-herz antibody therapy for cancers characterized by overexpression of the her2 receptor protein |
| WO2003099320A1 (en) * | 2002-05-24 | 2003-12-04 | Zensun (Shanghai) Sci-Tech.Ltd | Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy |
| US20070032557A1 (en) * | 2005-02-18 | 2007-02-08 | Matti Kivikko | Method for administering levosimendan |
| US20080279865A1 (en) | 2005-03-23 | 2008-11-13 | Pfizer, Inc., Pfizer Products, Inc. | Therapy of Prostate Cancer With Ctla-4 Antibodies and Hormonal Therapy |
| CA2658326C (en) | 2005-09-02 | 2013-04-23 | Morehouse School Of Medicine | Neuregulins for prevention and treatment of damage from acute assault on vascular and neuronal tissue |
| US20070213264A1 (en) * | 2005-12-02 | 2007-09-13 | Mingdong Zhou | Neuregulin variants and methods of screening and using thereof |
| US20070190127A1 (en) | 2005-12-30 | 2007-08-16 | Mingdong Zhou | Extended release of neuregulin for improved cardiac function |
| BRPI0908271A2 (pt) | 2008-02-29 | 2017-06-13 | Acorda Therapeutics Inc | método para alcançar níveis plasmáticos desejados de fator de crescimento glial |
| EP3632459A1 (en) * | 2008-07-17 | 2020-04-08 | Acorda Therapeutics, Inc. | Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure |
| PL2488194T3 (pl) | 2009-10-14 | 2016-11-30 | Zastosowanie neureguliny do leczenia uszkodzenia nerwu jamistego | |
| EP2603221A4 (en) | 2010-08-13 | 2014-02-26 | Univ Georgetown | GGF2 AND METHOD FOR ITS APPLICATION |
| EP2830645B1 (en) | 2012-03-30 | 2017-08-30 | Acorda Therapeutics, Inc. | Neuregulin for use in treating peripheral nerve injury |
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2009
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2013
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2014
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2015
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2018
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2020
- 2020-03-18 RU RU2020111236A patent/RU2020111236A/ru unknown
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2021
- 2021-11-04 JP JP2021179961A patent/JP2022023208A/ja active Pending
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| US6635249B1 (en) * | 1999-04-23 | 2003-10-21 | Cenes Pharmaceuticals, Inc. | Methods for treating congestive heart failure |
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| D HARARI1等: "Neuregulin-4: a novel growth factor that acts through the ErbB-4 receptor", 《ONCOGENE》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108778315A (zh) * | 2016-04-19 | 2018-11-09 | 莱布尼茨研究所-针对老化研究(弗里茨利普曼研究所) | 用于治疗和/或预防神经系统肿瘤的神经调节素 |
| CN110835368A (zh) * | 2018-08-15 | 2020-02-25 | 上海泽生科技开发股份有限公司 | 神经调节蛋白多肽片段及其用途 |
| WO2021052277A1 (zh) * | 2019-09-16 | 2021-03-25 | 上海泽生科技开发股份有限公司 | 重组人神经调节蛋白衍生物及其用途 |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11235031B2 (en) | Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure | |
| AU2020204070B2 (en) | Therapeutic dosing of a neuregulin or a fragment thereof for treatment or prophylaxis of heart failure | |
| HK1241715B (zh) | 用於治疗或预防心力衰竭的神经调节蛋白或其亚序列的治疗性施剂 | |
| HK40015761A (en) | Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure | |
| HK1256637B (en) | Therapeutic dosing of a neuregulin in the treatment or prophylaxis of heart failure | |
| HK1241715A1 (en) | Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure | |
| HK1157181A (en) | Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure | |
| HK1157181B (en) | Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure |
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Application publication date: 20150520 |