RU2536938C2 - Применение пептида ggf2 в лечении или профилактике сердечной недостаточности у млекопитающего - Google Patents

Применение пептида ggf2 в лечении или профилактике сердечной недостаточности у млекопитающего Download PDF

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RU2536938C2
RU2536938C2 RU2011105821/10A RU2011105821A RU2536938C2 RU 2536938 C2 RU2536938 C2 RU 2536938C2 RU 2011105821/10 A RU2011105821/10 A RU 2011105821/10A RU 2011105821 A RU2011105821 A RU 2011105821A RU 2536938 C2 RU2536938 C2 RU 2536938C2
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Russia
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ggf2
peptide
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hours
egf
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RU2011105821/10A
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English (en)
Russian (ru)
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RU2011105821A (ru
Inventor
Энтони КАДЖАНО
Аниндита ГАНГУЛИ
Дженнифер АЙАСИ
Том ПЭРРИ
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Акорда Терапьютикс, Инк.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1883—Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
RU2011105821/10A 2008-07-17 2009-07-17 Применение пептида ggf2 в лечении или профилактике сердечной недостаточности у млекопитающего RU2536938C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13517108P 2008-07-17 2008-07-17
US61/135,171 2008-07-17
PCT/US2009/004130 WO2010030317A2 (en) 2008-07-17 2009-07-17 Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure

Related Child Applications (1)

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RU2014141514A Division RU2698090C2 (ru) 2008-07-17 2014-10-14 Терапевтическое дозирование нейрегулина или его подпоследовательности для лечения или профилактики сердечной недостаточности

Publications (2)

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RU2011105821A RU2011105821A (ru) 2012-08-27
RU2536938C2 true RU2536938C2 (ru) 2014-12-27

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RU2011105821/10A RU2536938C2 (ru) 2008-07-17 2009-07-17 Применение пептида ggf2 в лечении или профилактике сердечной недостаточности у млекопитающего
RU2014141514A RU2698090C2 (ru) 2008-07-17 2014-10-14 Терапевтическое дозирование нейрегулина или его подпоследовательности для лечения или профилактики сердечной недостаточности
RU2019125376A RU2719199C1 (ru) 2008-07-17 2019-08-12 Терапевтическое дозирование нейрегулина или его подпоследовательности для лечения или профилактики сердечной недостаточности
RU2020111236A RU2020111236A (ru) 2008-07-17 2020-03-18 Терапевтическое дозирование нейрегулина или его подпоследовательности для лечения или профилактики сердечной недостаточности

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RU2014141514A RU2698090C2 (ru) 2008-07-17 2014-10-14 Терапевтическое дозирование нейрегулина или его подпоследовательности для лечения или профилактики сердечной недостаточности
RU2019125376A RU2719199C1 (ru) 2008-07-17 2019-08-12 Терапевтическое дозирование нейрегулина или его подпоследовательности для лечения или профилактики сердечной недостаточности
RU2020111236A RU2020111236A (ru) 2008-07-17 2020-03-18 Терапевтическое дозирование нейрегулина или его подпоследовательности для лечения или профилактики сердечной недостаточности

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US (5) US20110166068A1 (enExample)
EP (3) EP3338791B1 (enExample)
JP (5) JP5797112B2 (enExample)
CN (3) CN104623633A (enExample)
AU (3) AU2009292216B2 (enExample)
BR (1) BRPI0916442A2 (enExample)
CA (1) CA2731113A1 (enExample)
DK (2) DK2320933T3 (enExample)
ES (2) ES2664394T3 (enExample)
MX (2) MX384378B (enExample)
PL (2) PL3338791T3 (enExample)
RU (4) RU2536938C2 (enExample)
WO (1) WO2010030317A2 (enExample)

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CN104707130A (zh) 2008-08-15 2015-06-17 阿索尔达治疗公司 在cns神经性损伤后非-急性期间处理的组合物及方法
JP5743898B2 (ja) 2008-11-28 2015-07-01 ゼンサン (シャンハイ) サイエンス アンド テクノロジー リミテッド ニューレグリンペプチド及びその使用
AU2010306777C1 (en) 2009-10-14 2016-03-17 Acorda Therapeutics, Inc. Use of a neuregulin to treat peripheral nerve injury
WO2013053076A1 (en) 2011-10-10 2013-04-18 Zensun (Shanghai)Science & Technology Limited Compositions and methods for treating heart failure
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CA2911848A1 (en) 2013-05-22 2014-11-27 Zensun (Shanghai) Science & Technology, Ltd. Extended release of neuregulin for treating heart failure
CN110946993A (zh) 2014-01-03 2020-04-03 上海泽生科技开发股份有限公司 纽兰格林制剂的配方
CN111407882A (zh) * 2014-10-17 2020-07-14 上海泽生科技开发股份有限公司 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物
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US11426447B2 (en) * 2016-04-19 2022-08-30 Leibniz-Institut Fur Alternsforschung—Fritz-Lipmann-Institut E.V. (Fli) Neuregulin for the treatment of tumors of the nervous system
CN110835368A (zh) * 2018-08-15 2020-02-25 上海泽生科技开发股份有限公司 神经调节蛋白多肽片段及其用途
AR121035A1 (es) 2019-04-01 2022-04-13 Lilly Co Eli Compuestos de neuregulina-4 y métodos de uso
US12649769B2 (en) 2019-09-16 2026-06-09 Zensun (Shanghai) Science & Technology, Co., Ltd. Recombinant human neuregulin derivatives and use thereof
WO2023070078A1 (en) * 2021-10-22 2023-04-27 The Research Institute At Nationwide Children's Hospital Neuregulin for protection against respiratory viral infection and post-viral disease

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Also Published As

Publication number Publication date
EP3338791B1 (en) 2019-09-18
AU2017203528A1 (en) 2017-06-15
CN107019794B (zh) 2021-03-12
ES2763184T3 (es) 2020-05-27
US20110166068A1 (en) 2011-07-07
US20200009228A1 (en) 2020-01-09
JP2011528353A (ja) 2011-11-17
EP2320933A1 (en) 2011-05-18
WO2010030317A2 (en) 2010-03-18
JP6189879B2 (ja) 2017-08-30
JP2015129137A (ja) 2015-07-16
US20160113999A1 (en) 2016-04-28
CA2731113A1 (en) 2010-03-18
CN102159236A (zh) 2011-08-17
JP5797112B2 (ja) 2015-10-21
PL3338791T3 (pl) 2020-04-30
JP2019196370A (ja) 2019-11-14
AU2009292216B2 (en) 2015-03-05
AU2009292216A1 (en) 2010-03-18
RU2020111236A3 (enExample) 2021-09-21
CN107019794A (zh) 2017-08-08
DK2320933T3 (en) 2018-04-16
RU2719199C1 (ru) 2020-04-17
PL2320933T3 (pl) 2018-07-31
EP2320933A4 (en) 2013-02-27
BRPI0916442A2 (pt) 2018-06-19
AU2015202877A1 (en) 2015-06-18
RU2020111236A (ru) 2021-09-21
RU2011105821A (ru) 2012-08-27
EP3632459A1 (en) 2020-04-08
US9198951B2 (en) 2015-12-01
JP2022023208A (ja) 2022-02-07
US11235031B2 (en) 2022-02-01
ES2664394T3 (es) 2018-04-19
EP2320933B1 (en) 2017-12-27
EP3338791A1 (en) 2018-06-27
US20130324466A1 (en) 2013-12-05
US20180280477A1 (en) 2018-10-04
MX384378B (es) 2025-03-14
RU2698090C2 (ru) 2019-08-22
RU2014141514A (ru) 2016-05-10
MX2011000696A (es) 2011-07-29
AU2015202877B2 (en) 2017-03-09
JP2017200949A (ja) 2017-11-09
HK1256637A1 (en) 2019-09-27
US9956266B2 (en) 2018-05-01
CN104623633A (zh) 2015-05-20
DK3338791T3 (da) 2019-12-16

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