CN104620111B - 鉴定具有异常分数缩短的患者 - Google Patents
鉴定具有异常分数缩短的患者 Download PDFInfo
- Publication number
- CN104620111B CN104620111B CN201380047272.0A CN201380047272A CN104620111B CN 104620111 B CN104620111 B CN 104620111B CN 201380047272 A CN201380047272 A CN 201380047272A CN 104620111 B CN104620111 B CN 104620111B
- Authority
- CN
- China
- Prior art keywords
- subject
- amount
- sample
- fgf
- subjects
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Clinical applications
- A61B8/0883—Clinical applications for diagnosis of the heart
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4703—Regulators; Modulating activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4703—Regulators; Modulating activity
- G01N2333/4706—Regulators; Modulating activity stimulating, promoting or activating activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4712—Muscle proteins, e.g. myosin, actin, protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/50—Fibroblast growth factors [FGF]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/329—Diseases of the aorta or its branches, e.g. aneurysms, aortic dissection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Radiology & Medical Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- High Energy & Nuclear Physics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12184085 | 2012-09-12 | ||
| EP12184085.4 | 2012-09-12 | ||
| PCT/EP2013/056706 WO2014040759A1 (en) | 2012-09-12 | 2013-03-28 | Identification of patients with abnormal fractional shortening |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104620111A CN104620111A (zh) | 2015-05-13 |
| CN104620111B true CN104620111B (zh) | 2017-08-08 |
Family
ID=46826365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380047272.0A Active CN104620111B (zh) | 2012-09-12 | 2013-03-28 | 鉴定具有异常分数缩短的患者 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20150185230A1 (enExample) |
| EP (3) | EP4075143A1 (enExample) |
| JP (2) | JP6247302B2 (enExample) |
| CN (1) | CN104620111B (enExample) |
| CA (1) | CA2883890C (enExample) |
| ES (2) | ES2680149T3 (enExample) |
| WO (1) | WO2014040759A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103998938B (zh) | 2011-10-17 | 2016-06-15 | 霍夫曼-拉罗奇有限公司 | 风险患者和中风原因的基于肌钙蛋白和bnp的诊断 |
| ES2939018T3 (es) | 2014-03-26 | 2023-04-18 | Hoffmann La Roche | IGFBP7 para diagnosticar una disfunción diastólica |
| EP4300104A3 (en) * | 2014-10-29 | 2024-09-25 | Roche Diagnostics GmbH | Biomarker for risk prediction of mortality |
| CN108139409B (zh) | 2015-10-08 | 2020-07-24 | 豪夫迈·罗氏有限公司 | 当在外科手术之前测量时用于预测aki的风险的igfbp7 |
| WO2017125406A1 (en) * | 2016-01-19 | 2017-07-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of predicting left ventricular remodeling in subjects suffering from hypertension |
| AU2018275236B2 (en) * | 2017-05-30 | 2024-11-07 | Abbott Laboratories | Methods for aiding in diagnosing and evaluating a mild traumatic brain injury in a human subject using cardiac troponin I |
| ES2977423T3 (es) | 2017-12-13 | 2024-08-23 | Hoffmann La Roche | Angiopoyetina-2 (Ang-2) circulante y proteína de unión al factor de crecimiento insulínico 7 (IGFBP7) para la predicción de apoplejía |
| JP7024576B2 (ja) * | 2018-04-20 | 2022-02-24 | オムロンヘルスケア株式会社 | 電子血圧計および心不全検出器 |
| US11446009B2 (en) | 2018-12-11 | 2022-09-20 | Eko.Ai Pte. Ltd. | Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images |
| US11931207B2 (en) | 2018-12-11 | 2024-03-19 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device |
| US12322100B2 (en) | 2018-12-11 | 2025-06-03 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity |
| US12400762B2 (en) | 2018-12-11 | 2025-08-26 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy |
| US12001939B2 (en) | 2018-12-11 | 2024-06-04 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views |
| WO2023175176A1 (en) * | 2022-03-18 | 2023-09-21 | Roche Diagnostics Gmbh | Cmybpc marker combinations for early discrimination of type 2 versus type 1 acute myocardial infarction |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| GB9211686D0 (en) | 1992-06-03 | 1992-07-15 | Medisinsk Innovation A S | Chemical compounds |
| US6709855B1 (en) | 1998-12-18 | 2004-03-23 | Scios, Inc. | Methods for detection and use of differentially expressed genes in disease states |
| JP2004532202A (ja) * | 2001-03-15 | 2004-10-21 | シアオ,ヨング−フー | 生存哺乳動物における臨床的に認められた形態の心臓の病状を治療的に処置する方法 |
| US7632647B2 (en) | 2001-04-13 | 2009-12-15 | Biosite Incorporated | Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes |
| US7713705B2 (en) * | 2002-12-24 | 2010-05-11 | Biosite, Inc. | Markers for differential diagnosis and methods of use thereof |
| DE60233301D1 (de) | 2001-05-04 | 2009-09-24 | Biosite Inc | Diagnostische marker für akute herzerkrankungen und verfahren des gebrauchs |
| WO2003043487A2 (en) * | 2001-11-19 | 2003-05-30 | Protometrix, Inc. | Method of using a non-antibody protein to detect and measure an analyte |
| JP2005291899A (ja) * | 2004-03-31 | 2005-10-20 | Akira Matsumori | 心疾患の検査法 |
| US8563328B2 (en) * | 2004-07-26 | 2013-10-22 | University Of Louisville Research Foundation, Inc. | Fiber-optic biosensor and biosensing methods |
| US20080027330A1 (en) * | 2006-05-15 | 2008-01-31 | Endothelix, Inc. | Risk assessment method for acute cardiovascular events |
| WO2008060618A2 (en) * | 2006-11-15 | 2008-05-22 | University Of Florida Research Foundation | Use of genetic determinants in cardiovascular risk assessment |
| PL2115477T3 (pl) * | 2007-01-25 | 2015-12-31 | Hoffmann La Roche | Zastosowanie IGFBP-7 do oceny niewydolności serca |
| US8182998B2 (en) * | 2007-04-26 | 2012-05-22 | Genera Istrazivanja D.O.O. | Blood biomarkers for bone fracture and cartilage injury |
| EP2515116A1 (en) | 2007-05-18 | 2012-10-24 | Duke University | Serum biomarkers for the early detection of lung cancer |
| US20110183434A1 (en) * | 2008-01-17 | 2011-07-28 | Myles Wolf | Diagnostic methods and kits using fibroblast growth factor-23 |
| US20120010094A1 (en) * | 2008-11-06 | 2012-01-12 | Musc Foundation For Research Development | Detecting and monitoring left ventricular hypertrophy and congestive heart failure by profiling biomarkers |
| CN102448927A (zh) | 2009-04-01 | 2012-05-09 | 力奇制药公司 | 活性亚甲基基团的二甲基化的方法 |
| CN102422157B (zh) * | 2009-04-27 | 2014-10-29 | 霍夫曼-拉罗奇有限公司 | 内皮抑制素作为心力衰竭标记的应用 |
| CA2769243C (en) | 2009-07-27 | 2017-08-22 | F. Hoffmann-La Roche Ag | Use of mimecan in the assessment of heart failure |
| JP5763098B2 (ja) * | 2009-12-20 | 2015-08-12 | アスチュート メディカル,インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| EP2924439B1 (en) * | 2010-03-26 | 2017-02-01 | MyCartis N.V. | Ltbp2 as a biomarker for predicting or prognosticating mortality |
| US20120142632A1 (en) * | 2010-08-04 | 2012-06-07 | St. Vincent's Institute Of Medical Research | Diagnostic and prognostic assay |
| JP5676763B2 (ja) | 2010-08-26 | 2015-02-25 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 動脈性高血圧症から心不全への初期移行の評価におけるバイオマーカーの使用 |
| WO2012029837A1 (ja) * | 2010-08-31 | 2012-03-08 | 協和メデックス株式会社 | 線維芽細胞増殖因子-23の測定方法及び測定試薬 |
-
2013
- 2013-03-28 EP EP22161423.3A patent/EP4075143A1/en active Pending
- 2013-03-28 EP EP13713175.1A patent/EP2895866B1/en active Active
- 2013-03-28 JP JP2015531492A patent/JP6247302B2/ja active Active
- 2013-03-28 WO PCT/EP2013/056706 patent/WO2014040759A1/en not_active Ceased
- 2013-03-28 ES ES13713175.1T patent/ES2680149T3/es active Active
- 2013-03-28 EP EP18174585.2A patent/EP3428649B1/en active Active
- 2013-03-28 ES ES18174585T patent/ES2913539T3/es active Active
- 2013-03-28 CA CA2883890A patent/CA2883890C/en active Active
- 2013-03-28 CN CN201380047272.0A patent/CN104620111B/zh active Active
-
2015
- 2015-03-11 US US14/644,695 patent/US20150185230A1/en not_active Abandoned
-
2017
- 2017-11-16 JP JP2017220660A patent/JP6615848B2/ja active Active
-
2018
- 2018-03-05 US US15/911,699 patent/US11454634B2/en active Active
-
2022
- 2022-08-19 US US17/891,458 patent/US20220412991A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3428649A2 (en) | 2019-01-16 |
| JP6247302B2 (ja) | 2017-12-13 |
| JP6615848B2 (ja) | 2019-12-04 |
| US11454634B2 (en) | 2022-09-27 |
| CA2883890C (en) | 2021-11-09 |
| EP2895866A1 (en) | 2015-07-22 |
| CA2883890A1 (en) | 2014-03-20 |
| EP3428649A3 (en) | 2019-02-13 |
| JP2015531873A (ja) | 2015-11-05 |
| EP2895866B1 (en) | 2018-05-30 |
| US20220412991A1 (en) | 2022-12-29 |
| ES2913539T3 (es) | 2022-06-02 |
| ES2680149T3 (es) | 2018-09-04 |
| WO2014040759A1 (en) | 2014-03-20 |
| CN104620111A (zh) | 2015-05-13 |
| EP3428649B1 (en) | 2022-03-23 |
| US20180196067A1 (en) | 2018-07-12 |
| JP2018049032A (ja) | 2018-03-29 |
| EP4075143A1 (en) | 2022-10-19 |
| HK1206097A1 (en) | 2015-12-31 |
| US20150185230A1 (en) | 2015-07-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20220412991A1 (en) | Identification of patients with abnormal fractional shortening | |
| JP6654668B2 (ja) | 発作性心房細動のbnp型ペプチドに基づく診断をするためのデータを提供する方法 | |
| JP7033634B2 (ja) | 心不全の治療選択におけるバイオマーカー | |
| US11047866B2 (en) | IGFBP7 for diagnosing diastolic dysfunction | |
| JP5419968B2 (ja) | 心臓治療を必要とする個体におけるl−fabp、ナトリウム利尿ペプチド及び心筋トロポニン | |
| JP6608285B2 (ja) | 心不全リスクの予測改善のためのバイオマーカー | |
| EP3446124A1 (en) | Soluble st2 for the identification of progressors to lvh in the general population | |
| HK1206097B (en) | Identification of patients with abnormal fractional shortening | |
| HK1234493A1 (en) | Igfbp7 for diagnosing diastolic dysfunction | |
| HK1234493B (zh) | 用於诊断舒张功能障碍的igfbp7 | |
| HK1212434B (en) | Tnt based diagnosis of paroxysmal atrial fibrillation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1206097 Country of ref document: HK |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: GR Ref document number: 1206097 Country of ref document: HK |