CN104619187A - 含有可氧化的活性物的微胶囊,和制备其的方法 - Google Patents

含有可氧化的活性物的微胶囊,和制备其的方法 Download PDF

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Publication number
CN104619187A
CN104619187A CN201380029714.9A CN201380029714A CN104619187A CN 104619187 A CN104619187 A CN 104619187A CN 201380029714 A CN201380029714 A CN 201380029714A CN 104619187 A CN104619187 A CN 104619187A
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CN
China
Prior art keywords
microcapsules
water
additional element
particles
vitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380029714.9A
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English (en)
Chinese (zh)
Inventor
P·布伊森
C·谢盖努
J-E·文德维勒
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Idcaps SAS
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Idcaps SAS
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Application filed by Idcaps SAS filed Critical Idcaps SAS
Priority to CN201911097697.8A priority Critical patent/CN110916162A/zh
Publication of CN104619187A publication Critical patent/CN104619187A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/262—Cellulose; Derivatives thereof, e.g. ethers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/275—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of animal origin, e.g. chitin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P20/00—Coating of foodstuffs; Coatings therefor; Making laminated, multi-layered, stuffed or hollow foodstuffs
    • A23P20/10—Coating with edible coatings, e.g. with oils or fats
    • A23P20/15—Apparatus or processes for coating with liquid or semi-liquid products
    • A23P20/18—Apparatus or processes for coating with liquid or semi-liquid products by spray-coating, fluidised-bed coating or coating by casting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/446—Superoxide dismutase (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D1/00—Processes for applying liquids or other fluent materials
    • B05D1/18—Processes for applying liquids or other fluent materials performed by dipping
    • B05D1/22—Processes for applying liquids or other fluent materials performed by dipping using fluidised-bed technique

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201380029714.9A 2012-04-12 2013-04-12 含有可氧化的活性物的微胶囊,和制备其的方法 Pending CN104619187A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201911097697.8A CN110916162A (zh) 2012-04-12 2013-04-12 含有可氧化的活性物的微胶囊，和制备其的方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261623210P 2012-04-12 2012-04-12
EP12305434 2012-04-12
EP12305434.8 2012-04-12
US61/623,210 2012-04-12
PCT/EP2013/057739 WO2013153220A1 (en) 2012-04-12 2013-04-12 Microcapsules containing an oxidizable active, and a process for preparing the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201911097697.8A Division CN110916162A (zh) 2012-04-12 2013-04-12 含有可氧化的活性物的微胶囊，和制备其的方法

Publications (1)

Publication Number Publication Date
CN104619187A true CN104619187A (zh) 2015-05-13

Family

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CN201380029714.9A Pending CN104619187A (zh) 2012-04-12 2013-04-12 含有可氧化的活性物的微胶囊,和制备其的方法
CN201911097697.8A Pending CN110916162A (zh) 2012-04-12 2013-04-12 含有可氧化的活性物的微胶囊，和制备其的方法

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Country Status (9)

Country Link
US (3) US9308178B2 (cg-RX-API-DMAC7.html)
EP (1) EP2836079B1 (cg-RX-API-DMAC7.html)
JP (1) JP6543190B2 (cg-RX-API-DMAC7.html)
CN (2) CN104619187A (cg-RX-API-DMAC7.html)
AU (1) AU2013246821B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014029264B1 (cg-RX-API-DMAC7.html)
CA (1) CA2874791C (cg-RX-API-DMAC7.html)
IN (1) IN2014DN08496A (cg-RX-API-DMAC7.html)
WO (1) WO2013153220A1 (cg-RX-API-DMAC7.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107252108A (zh) * 2017-06-27 2017-10-17 福建农林大学 一种乳糖酶微胶囊及其制备方法
CN109619536A (zh) * 2018-10-18 2019-04-16 山东海能生物工程有限公司 一种25-羟基维生素d3微囊粉及其制备方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2863048T3 (es) * 2014-05-05 2021-10-08 Basf Se Formulación de vitamina liposoluble
CN107949377B (zh) * 2015-09-09 2020-11-06 帝斯曼知识产权资产管理有限公司 生产包含治疗活性或营养性植物提取物的制剂的方法
MY202355A (en) * 2018-03-01 2024-04-24 463Ip Partners Llc Microencapsulated products, clear solutions thereof, and methods of making
US12653782B2 (en) 2019-09-12 2026-06-16 Nulixir Inc. Controlled release concentrate and suspensions including the same
CN117794389A (zh) 2021-06-03 2024-03-29 Bionov公司 包含超氧化物歧化酶(sod)的植物活性提取物与胡芦巴提取物的组合及其用途
US12691078B2 (en) 2021-09-14 2026-07-28 Nulixir Inc. Stable compositions of functional ingredients and methods of making the same
WO2023099493A1 (en) * 2021-12-03 2023-06-08 Dsm Ip Assets B.V. New delivery system for vitamin c

Citations (6)

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US3714065A (en) * 1970-02-03 1973-01-30 Fuji Photo Film Co Ltd Process for preparing a micro capsule
EP1300394A1 (en) * 2000-07-13 2003-04-09 Vitatene, S.A. Method for the production of a water-dispersible formulation containing carotenoids
US20070141211A1 (en) * 2005-12-16 2007-06-21 Solae, Llc Encapsulated Phospholipid-Stabilized Oxidizable Material
US20090004333A1 (en) * 2007-06-27 2009-01-01 Bunge Oils, Inc. Microencapsulated Oil Product and Method of Making Same
CN101742988A (zh) * 2006-06-05 2010-06-16 加拿大海洋营养食品有限公司 具有改进壳层的微胶囊
CN102112219A (zh) * 2008-07-31 2011-06-29 溶胶凝胶技术公司 包含有效成分和金属氧化物壳的微胶囊,其制备方法及其用途

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US2348503A (en) * 1941-08-23 1944-05-09 Atlantic Coast Fisheries Co Vitamin preparation and method of making same
US3396116A (en) * 1965-09-07 1968-08-06 Amp Inc Encapsulation technique
US4123382A (en) * 1973-05-25 1978-10-31 Merck & Co., Inc. Method of microencapsulation
US5418010A (en) * 1990-10-05 1995-05-23 Griffith Laboratories Worldwide, Inc. Microencapsulation process
JP3555640B2 (ja) * 1996-05-10 2004-08-18 ライオン株式会社 天然カロチノイドを包含した多芯型構造のマイクロカプセル並びに錠剤、食品用及び医薬品用配合剤
JP3447042B2 (ja) * 1997-07-23 2003-09-16 フロイント産業株式会社 単一物質球形粒の製造方法
US7097868B2 (en) * 2001-08-23 2006-08-29 Bio-Dar Ltd. Stable coated microcapsules
DE10164110A1 (de) * 2001-12-24 2003-07-10 Dragoco Gerberding Co Ag Mononuklear gefüllte Mikrokapseln
US6663900B2 (en) * 2002-02-01 2003-12-16 Kemin Foods, Lc Microcapsules having high carotenoid content
US20110020519A1 (en) * 2008-01-04 2011-01-27 Aveka, Inc. Encapsulation of oxidatively unstable compounds
WO2010146845A1 (ja) * 2009-06-19 2010-12-23 富士カプセル株式会社 ソフトカプセル及びその製造方法
EP2305742B1 (en) * 2009-10-01 2017-02-22 Symrise AG Spherical core-shell-particle

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714065A (en) * 1970-02-03 1973-01-30 Fuji Photo Film Co Ltd Process for preparing a micro capsule
EP1300394A1 (en) * 2000-07-13 2003-04-09 Vitatene, S.A. Method for the production of a water-dispersible formulation containing carotenoids
US20070141211A1 (en) * 2005-12-16 2007-06-21 Solae, Llc Encapsulated Phospholipid-Stabilized Oxidizable Material
CN101742988A (zh) * 2006-06-05 2010-06-16 加拿大海洋营养食品有限公司 具有改进壳层的微胶囊
US20090004333A1 (en) * 2007-06-27 2009-01-01 Bunge Oils, Inc. Microencapsulated Oil Product and Method of Making Same
CN102112219A (zh) * 2008-07-31 2011-06-29 溶胶凝胶技术公司 包含有效成分和金属氧化物壳的微胶囊,其制备方法及其用途

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107252108A (zh) * 2017-06-27 2017-10-17 福建农林大学 一种乳糖酶微胶囊及其制备方法
CN109619536A (zh) * 2018-10-18 2019-04-16 山东海能生物工程有限公司 一种25-羟基维生素d3微囊粉及其制备方法

Also Published As

Publication number Publication date
BR112014029264A2 (pt) 2017-06-27
US10111857B2 (en) 2018-10-30
JP2015519883A (ja) 2015-07-16
WO2013153220A1 (en) 2013-10-17
US20140037744A1 (en) 2014-02-06
CA2874791A1 (en) 2013-10-17
US20190022058A1 (en) 2019-01-24
AU2013246821B2 (en) 2016-07-21
AU2013246821A1 (en) 2015-02-12
US20160184264A1 (en) 2016-06-30
IN2014DN08496A (cg-RX-API-DMAC7.html) 2015-05-08
BR112014029264B1 (pt) 2021-01-05
CN110916162A (zh) 2020-03-27
US9308178B2 (en) 2016-04-12
CA2874791C (en) 2020-09-01
JP6543190B2 (ja) 2019-07-10
EP2836079A1 (en) 2015-02-18
EP2836079B1 (en) 2022-09-14

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Application publication date: 20150513