CN104606414A - Composition for treating hyperostosis and preparation method for composition - Google Patents
Composition for treating hyperostosis and preparation method for composition Download PDFInfo
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Abstract
The invention discloses composition for treating hyperostosis. The composition is prepared from the following raw materials in parts by weight: 1-5 parts of tortoise shells, 2-4 parts of calcium gluconate tablets, 3-7 parts of rhizoma cibotii, 2-6 parts of radix clematidis, 4-8 parts of cortex acanthopanacis, 10-15 parts of dandelions, 5-15 parts of frankincense, 5-10 parts of homalomena occulta, 2-4 parts of colchicine tablets, 4-8 parts of prepared rehmannia roots, 10-20 parts of ligusticum wallichii, 5-15 parts of rhizoma corydalis, 6-16 parts of asarum, 3-9 parts of drynaria rhizome and 10-14 parts of vitamin B. Effective medicines are selected to form an important anti-hyperostosis medicine for external application. The composition has curative effects of softening sclerotin, relieving nerve compression and removing stasis to ease pain on cervical hyperplasia, lumbar vertebra hyperplasia, lumbar disc herniation, lumbar bone sprain and rheumatism bone pain.
Description
Technical field
The invention belongs to traditional Chinese medicine field, particularly relate to a kind of composition and method of making the same for the treatment of hyperosteogeny.
Background technology
Hypertrophic osteoarthritis refers to due to degeneration of joint, so that the chronic joint disease that articular cartilage is destroyed and causes.Also known as osteoarthritis, osteoarthritis and hypertrophiarthritis etc.
The cause of disease: Hypertrophic osteoarthritis has constitutional and Secondary cases two kinds.Constitutional is also known as idiopathic, aging based on human body natural, more rare; Secondary cases is then based on chronic strain and the wound day after tomorrow, more common.1. the Basic disease cause of constitutional osteoarthritis is, the aging gradually and degeneration after people's body maturation, the performance in osteoarthrosis.2. secondary osteoarthrosis refers to because of certain known reason, such as wound, operation or other obvious factors and the cartilage destruction that causes, or articulation structure changes.Due to factors such as articular surface friction or pressure imbalances, cause the degeneration of articular surface.In this type of case, great majority can find anatomy or dispositional exception.
Clinical manifestation: primary disease onset is slow, without General Symptoms, mostly is the person in middle and old age of more than 50 years old.Be often multi-joint morbidity, also have simple joint to send out patient.Affected joints can have persistence dull pain, increases the weight of during movable increase, takes a turn for the better after having a rest.Pain is often not serious, increases the weight of when air pressure reduces, relevant with climate change.Sometimes can there is acute pain episodes, have joint stiff sense simultaneously, can find that intraarticular has crunch once in a while.Sitting posterior joint is stiff to be increased the weight of, and take a turn for the better after slightly movable, someone is referred to as " rest pain ".Later stage arthroncus, increase and limitation of movement, little complete tetanus, generally shows as bone retardance and levies.
Authorization Notice No. CN 102138993 B(application number 201110067249.0) Chinese patent literature provide a kind of hyperosteogeny ointment, it is characterized in that it is made up of the crude drug of following weight proportioning: Borneolum Syntheticum: 6g, Agkistrodon: 2, Cortex Cinnamomi: 50g, Herba Taraxaci: 60g, Radix Et Rhizoma Rhei: 150g, Fructus Gardeniae: 20g, Fructus Chaenomelis: 20g, Eupolyphaga Seu Steleophaga: 20g, Olibanum: 20g, Moschus: 1g, Mel: 100g, vaseline: 45g.Authorization Notice No. CN 102319316 B(application number 201210508065.8) Chinese patent literature provide a kind of medicine for the treatment of hyperosteogeny, be made up of the medical material of following weight proportion: Herba Adenosmae Glutinosi 10-25 gram, Rhizoma Drynariae 5-15 gram, Rhizoma Cibotii 5-15 gram, DAJIEGU 5-15 gram, Hirudo 5-15 gram, Radix Rehmanniae Preparata 5-15 gram, Olibanum 5-15 gram, Olibanum 5-15 gram, Radix et Rhizoma Dysosmatis 10-25 gram, roasted SQUAMA MANITIS into puffy with sand 5-15 gram.
Summary of the invention
For the present situation of existing treatment hyperosteogeny deficiency, and provide the composition and method of making the same for the treatment of hyperosteogeny, there is easy to operate, the evident in efficacy and feature had no side effect, can also improve inside of human body immunologic function, the resistance against diseases of enhancing body, to hyperosteogeny, hyperosteogeny, prolapse of lumbar intervertebral disc, neck bone is outstanding, pelvic bone is sprained, rheumatic ostalgia, use medicine for quickly curing osteoproliferation external application, play softening sclerotin, alleviate pressuring nerve, the healing effect of stasis-dispelling and pain-killing.
Another object of the present invention is just to provide the preparation method of above-mentioned composition.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The compositions for the treatment of hyperosteogeny, each crude drug is as follows, is weight portion: Carapax et Plastrum Testudinis 1-5, calcium gluconate tablet 2-4, Rhizoma Cibotii 3-7, Radix Clematidis 2-6, Cortex Acanthopancis 4-8, Herba Taraxaci 10-15, Olibanum 5-15, Rhizoma Homalomenae 5-10, colchicines tablets 2-4, Radix Rehmanniae Preparata 4-8, Rhizoma Chuanxiong 10-20, Rhizoma Corydalis 5-15, Herba Asari 6-16, Rhizoma Drynariae 3-9, vitaminB10-14.
The compositions for the treatment of hyperosteogeny, preferred scheme is, each crude drug is as follows, be weight portion: Carapax et Plastrum Testudinis 2-4, calcium gluconate tablet 2.5-3.5, Rhizoma Cibotii 4-6, Radix Clematidis 4-6, Cortex Acanthopancis 5-7, Herba Taraxaci 11-14, Olibanum 8-13, Rhizoma Homalomenae 6-9, colchicines tablets 2.5-3.5, Radix Rehmanniae Preparata 5-7, Rhizoma Chuanxiong 13-18, Rhizoma Corydalis 8-13, Herba Asari 10-12, Rhizoma Drynariae 5-7, VB11-13.
The compositions for the treatment of hyperosteogeny, better preferred scheme is that each crude drug is as follows, be weight portion: Carapax et Plastrum Testudinis 3, calcium gluconate tablet 3, Rhizoma Cibotii 5, Radix Clematidis 5, Cortex Acanthopancis 6, Herba Taraxaci 13, Olibanum 10, Rhizoma Homalomenae 7.5, colchicines tablets 3, Radix Rehmanniae Preparata 6, Rhizoma Chuanxiong 15, Rhizoma Corydalis 10, Herba Asari 11, Rhizoma Drynariae 6, vitamin B12.
The preparation method of above-mentioned composition, step is as follows:
(1) dry clean for Carapax et Plastrum Testudinis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 80-120 mesh sieve stand-by;
(2) Rhizoma Cibotii, Radix Clematidis, Cortex Acanthopancis and Herba Asari white vinegar is soaked 5-15 hour, steam 20-40 minute, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 80-120 mesh sieve for subsequent use for pulverization altogether;
(3) Herba Taraxaci, Olibanum, Rhizoma Homalomenae, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Rhizoma Corydalis and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry 4-8 minute fast, and sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) calcium gluconate tablet, colchicines tablets and the vitamin B slender roll of medicated paper or gauze are pulverized; add the boiled water of calcium gluconate tablet, colchicines tablets and vitamin B5-10 times; soak 5-10 hour; add step (1)-(3) gained smalls; little fire is heated to boiling; stir; change slow fire boiling 30-50 hour; leave standstill 12-16 hour; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
The preparation method of foregoing compositions, step (1) smalls crosses 90-110 mesh sieve stand-by (preferred, it is stand-by that smalls crosses 100 mesh sieves).
The preparation method of foregoing compositions, Rhizoma Cibotii, Radix Clematidis, Cortex Acanthopancis and Herba Asari white vinegar soaks 8-13 hour (preferred, Rhizoma Cibotii, Radix Clematidis, Cortex Acanthopancis and Herba Asari white vinegar are soaked 10 hours) by step (2).
The preparation method of foregoing compositions, step (2) steams 25-35 minute (preferred, to steam 30 minutes).
The preparation method of foregoing compositions, step (3) drops into the crude drug cut, and stir-fry 5-7 minute (preferred, to drop into the crude drug cut, stir-fry fast 6 minutes) fast.
The preparation method of foregoing compositions, step (4) adds the boiled water of calcium gluconate tablet, colchicines tablets and vitamin B6-9 times, soak 6-9 hour (preferred, to add calcium gluconate tablet, colchicines tablets and vitamin B7 .5 boiled water doubly, soak 8 hours).
The preparation method of foregoing compositions, step (4) little fire is heated to boiling, stirs, change slow fire boiling 35-45 hour, (preferred, little fire is heated to boiling to leave standstill 13-15 hour, stir, change slow fire boiling 40 hours, leave standstill 14 hours).
Using method: for making the present invention reach optimum therapeuticing effect, three get oral medicine 3-5ml of the present invention, warm water delivery service after the meal, and external smearing ointment spreads upon affected part, wraps with bundle, and using once before sleep every night, 7 days is a course for the treatment of.
Said composition is to the Be very effective for the treatment of hyperosteogeny, the Chinese medicine of Chinese medicine employing blood circulation promoting and blood stasis dispelling of the present invention, relaxing muscles and tendons and activating QI and blood in the collateral, QI invigorating pain relieving, strong bone of enriching blood and analgesic antiphlogistic are good for the Western medicine of bone, reasonable compatibility, improve body immunity, have no side effect, improve the body constitution of patient's weakness because of chronic pain, and the local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The composition and method of making the same for the treatment of hyperosteogeny, the pharmacological effect of each crude drug is respectively:
Carapax et Plastrum Testudinis: YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, strong bone.Control deficiency of kidney yin, hectic fever due to YIN-deficiency consumptive fever, spit blood, epistaxis, chronic cough, seminal emission, metrorrhagia, leukorrhagia, lumbago, the atrophic debility of bones, stirring of wind due to deficiency of YIN, chronic dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.
Calcium gluconate tablet: calcium gluconate tablet, indication is for prevention and therapy calcium deficiency, as osteoporosis, tetany disease, dysosteogenesis, rickets and child, gestation and women breast-feeding their children, menopausal women, the supplementing of old people's calcium.
Rhizoma Cibotii: nature and flavor: bitter in the mouth, sweet, warm in nature.Gui Jing: return liver, kidney channel.Effect: wind-damp dispelling, invigorating the liver and kidney, strong waist knee joint.Cure mainly: for rheumatic arthralgia, soreness of the waist and knees, weakness of the lower extremities.
Radix Clematidis: have wind-damp dispelling, the effect of the meridian dredging.For rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness.
Cortex Acanthopancis: nature and flavor acrid in the mouth, hardship, warm in nature.Gui Jing: liver, kidney channel.Function has wind-damp dispelling, liver and kidney tonifying, bone and muscle strengthening, the effect of inducing diuresis to remove edema.Cure mainly: for Bi condition, muscles and bones flaccidity is soft, children's's walking retardation in children, and body void is weak, edema, beriberi.
Herba Taraxaci: containing multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, inulin in Herba Taraxaci plant.Nature and flavor are sweet, micro-hardship, cold.Return liver, stomach warp.There are the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.Control pyretic toxicity, carbuncle, skin infection, abscess of internal organ, conjunctival congestion and swelling pain, damp and hot, the puckery pain of jaundice, dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection etc.Herba Taraxaci is raw-eaten, stir-fry and eat, cook soup, is the plant of dietotherapeutic.
Olibanum: nature and flavor: pungent, bitter, temperature.Gui Jing: GUIXIN, liver, spleen channel.Effect: blood-activating and qi-promoting pain relieving, detumescence and promoting granulation.Cure mainly: for obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation, lump in the abdomen is suffered from abdominal pain, rheumatic arthralgia, the contracture of muscle arteries and veins, traumatic injury, carbuncle skin infection.
Rhizoma Homalomenae: nature and flavor: bitter in the mouth, pungent, warm in nature.Gui Jing: liver, kidney channel.Function: have wind-damp dispelling, effect of strengthening bone and muscle.Cure mainly: for anemofrigid-damp arthralgia, chills and pain of the waist and kness, contracture is numb, and muscles and bones flaccidity is soft.
Colchicines tablets: colchicines tablets, indication is the acute attack for the treatment of gouty arthritis, the acute attack of prevention of recurrence gouty arthritis.
Radix Rehmanniae Preparata: sweet, tepor.Return liver, kidney channel, yin nourishing of enriching blood, life essence-filling, marrow-benefitting, Radix Rehmanniae sweet-bitter flavor, cold in nature and enter blood system, clearing away heat and cooling blood.Cure mainly fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon hinders constipation.
Radix Rehmanniae Preparata sweet in the mouth, property are flat and enter blood system, function nourishing YIN and supplementing blood, vital essence replenishing and marrow benifiting.Control deficiency of YIN insufficiency of blood, the hollow institute of brains waist knee flaccidity, chronic cough hectic fever due to YIN-deficiency extremely, seminal emission, metrorrhagia, menoxenia, quenches one's thirst, frequency of micturition, deafness, blurred vision, palpitation and insomnia, forgetful, night sweat etc.
Rhizoma Chuanxiong: activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature.There is promoting blood circulation to remove blood stasis, the function of promoting the circulation of QI pain relieving.For whole body each portion qi depression to blood stasis pain, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain.
Herba Asari: dispel the wind, cold expelling, row water, the effect such as to have one's ideas straightened out.Be usually used in air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia etc.Herba Asari can outer dispersing wind and cold, again can in dispel YIN-cold, pain relieving simultaneously, antitussive effect are better.
Rhizoma Drynariae: the kidney invigorating bone strengthening, continues and hinders pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.The kidney invigorating, invigorates blood circulation, hemostasis.Control suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus.
Vitamin B: the most frequent member of vitamin B extended familys has B1.B2.B3(nicotinic acid), B5(pantothenic acid), B6.B9(folic acid) B12(cobalamine).Their effect is described below.1. are critical materials in carbohydrate metabolism process.Muscle and the neural institute energy requirement of health provide primarily of saccharide, so the most easily get involved.VB is sufficient, then neurocyte energetic, can alleviate worry, anxiety, increases the holding capacity to noise etc.; Otherwise, cause the ability of answering pressure to fail, even cause neuritis.Cardiac function is influenced due to the deposition of acetone acid, lactic acid.The deficient scarce energy of the intestines and stomach, wriggles unable, digestive function weakness, and produces constipation.Vitamin B1 deficiency is caused time serious.Its evolutionary process is: body void-tired-irritated, depressed-constipation-neuritis-pained-heart failure-edema.Dutch doctor in 1897 finds that edible polished rice can cause vitamin B1 deficiency.Mainly in default of vitamin B1, so B1 is also called anti beriberi vitamin.Diet very important 2. is closely related with the metabolism of sugar, protein, fat.Maintain and improve epithelial tissue, as the epithelial tissue of eyes, the health of alimentary canal mucous membrane tissue.Asthenopia, conjunctival hyperemia, angular cheilitis etc. are had during famine.When angular cheilitis doctor usually can want patient to take riboflavin, namely B2.3. the bad meeting of lipid metabolism causes seborrheic dermatitis, small pox, acne, and vitimin supplement B has good effect.4. lack B race so that gastrointestinal peristalsis is unable, digestive juice secretion is bad, causes dyspepsia, constipation, halitosis, stool cacosmia.5.B3 forms the coenzyme of dehydrogenase in vivo, plays an important role, cause nerve, skin, Alimentary tract disease, be called pellagra, also cry three D diseases, show as dermatitis, diarrhoea and dementia during famine in the metabolism of carbohydrate, protein, fat.6. help bodily tissue to utilize oxygen, what promote skin, fingernail, hair tissue obtains oxygen amount, dispels or improves the dandruff.7. the toxin such as relieving alcohol and nicotine, releive headache, migraine, the liver protecting.The shortage of 8.B11.B12 by affect thymus pyrimidine, purine, etc. synthesis, cause DNA dyssynthesis.Finally cause erythrocytic nucleus immature, generate ineffectivity erythrocyte, Here it is megaloblastic anemia.9. as lacked folic acid at conceived in 3 months, can Fetal neurotubules malformation be caused, thus increase and split animal brains, the incidence rate of anencephaly.10.B vitamin (mainly vitamin B1) has a kind of special abnormal smells from the patient, is the vitamin that mosquito is detested, thus has repelling effect to a certain degree.
The present composition is based on the principle of traditional Chinese medical herbal treatment hyperosteogeny, the existing benefiting qi and nourishing blood of the Chinese medicinal material selected, effect of regulating the flow of Qi and the middle Jiao, relaxing muscles and tendons to promote blood circulation, strong muscle key bone, treatment hyperosteogeny, Chinese medicine and Western medicine are mixed the compositions being prepared into and treating hyperosteogeny, cheap, life-time service also can not cause the financial burden of patient, is to treat the ideal medicine of hyperosteogeny.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1the compositions for the treatment of hyperosteogeny, each crude drug is as follows, is weight portion (getting 10g for every part): Carapax et Plastrum Testudinis 1, calcium gluconate tablet 2, Rhizoma Cibotii 3, Radix Clematidis 2, Cortex Acanthopancis 4, Herba Taraxaci 10, Olibanum 5, Rhizoma Homalomenae 5, colchicines tablets 2, Radix Rehmanniae Preparata 4, Rhizoma Chuanxiong 10, Rhizoma Corydalis 5, Herba Asari 6, Rhizoma Drynariae 3, vitaminB10.
The preparation method of the compositions of above-mentioned treatment hyperosteogeny, step is:
(1) dry clean for Carapax et Plastrum Testudinis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 80 mesh sieves stand-by;
(2) Rhizoma Cibotii, Radix Clematidis, Cortex Acanthopancis and Herba Asari white vinegar are soaked 5 hours, steam 20 minutes, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 80 mesh sieves for subsequent use for pulverization altogether;
(3) Herba Taraxaci, Olibanum, Rhizoma Homalomenae, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Rhizoma Corydalis and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry fast 4 minutes, sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) calcium gluconate tablet, colchicines tablets and the vitamin B slender roll of medicated paper or gauze are pulverized; add calcium gluconate tablet, colchicines tablets and vitamin B5 boiled water doubly; soak 5 hours; add step (1)-(3) gained smalls; little fire is heated to boiling; stir; change slow fire boiling 30 hours; leave standstill 12 hours; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
embodiment 2the compositions for the treatment of hyperosteogeny, each crude drug is as follows, is weight portion (getting 15g for every part): Carapax et Plastrum Testudinis 5, calcium gluconate tablet 4, Rhizoma Cibotii 7, Radix Clematidis 6, Cortex Acanthopancis 8, Herba Taraxaci 15, Olibanum 15, Rhizoma Homalomenae 10, colchicines tablets 4, Radix Rehmanniae Preparata 8, Rhizoma Chuanxiong 20, Rhizoma Corydalis 15, Herba Asari 16, Rhizoma Drynariae 9, VB14.
The preparation method of the compositions of above-mentioned treatment hyperosteogeny, step is:
(1) dry clean for Carapax et Plastrum Testudinis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 120 mesh sieves stand-by;
(2) Rhizoma Cibotii, Radix Clematidis, Cortex Acanthopancis and Herba Asari white vinegar are soaked 15 hours, steam 40 minutes, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 120 mesh sieves for subsequent use for pulverization altogether;
(3) Herba Taraxaci, Olibanum, Rhizoma Homalomenae, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Rhizoma Corydalis and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry fast 8 minutes, sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) calcium gluconate tablet, colchicines tablets and the vitamin B slender roll of medicated paper or gauze are pulverized; add calcium gluconate tablet, colchicines tablets and vitaminB10 boiled water doubly; soak 10 hours; add step (1)-(3) gained smalls; little fire is heated to boiling; stir; change slow fire boiling 50 hours; leave standstill 16 hours; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
typical case one:wu XX, man, 55 years old, because of prolapse of lumbar intervertebral disc, causes left lower limb pain numbness.Be the treatment of several hospital clinic, cannot have cured.Some advocate to have an operation to hospital.But because of financial difficulties, after person's open surgery, need rest half a year.Because of economy and labour's problem, his disease has dragged 2 years, gives other treatments by Chinese herbs three months, and arthralgia is serious all the more, and lower limb is more dumb, and follow up a case by regular visits to and recur, doctor advised takes the present composition.
Use and coordinate embodiment 2 resulting composition, after three courses for the treatment of, flank pain alleviates, and both legs are also flexible, and sleep also obviously improves, and after 8 courses for the treatment of, the symptom of patient all disappears.
embodiment 3the compositions for the treatment of hyperosteogeny, each crude drug is as follows, is weight portion (getting 20g for every part): Carapax et Plastrum Testudinis 2, calcium gluconate tablet 2.5, Rhizoma Cibotii 4, Radix Clematidis 4, Cortex Acanthopancis 5, Herba Taraxaci 11, Olibanum 8, Rhizoma Homalomenae 6, colchicines tablets 2.5, Radix Rehmanniae Preparata 5, Rhizoma Chuanxiong 13, Rhizoma Corydalis 8, Herba Asari 10, Rhizoma Drynariae 5, VB11.
The preparation method of the compositions of above-mentioned treatment hyperosteogeny, step is:
(1) dry clean for Carapax et Plastrum Testudinis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 90 mesh sieves stand-by;
(2) Rhizoma Cibotii, Radix Clematidis, Cortex Acanthopancis and Herba Asari white vinegar are soaked 8 hours, steam 25 minutes, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 90 mesh sieves for subsequent use for pulverization altogether;
(3) Herba Taraxaci, Olibanum, Rhizoma Homalomenae, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Rhizoma Corydalis and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry fast 5 minutes, sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) calcium gluconate tablet, colchicines tablets and the vitamin B slender roll of medicated paper or gauze are pulverized; add calcium gluconate tablet, colchicines tablets and vitamin B6 boiled water doubly; soak 6 hours; add step (1)-(3) gained smalls; little fire is heated to boiling; stir; change slow fire boiling 35 hours; leave standstill 13 hours; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
embodiment 4the compositions for the treatment of hyperosteogeny, each crude drug is as follows, is weight portion (getting 25g for every part): Carapax et Plastrum Testudinis 4, calcium gluconate tablet 3.5, Rhizoma Cibotii 6, Radix Clematidis 6, Cortex Acanthopancis 7, Herba Taraxaci 14, Olibanum 13, Rhizoma Homalomenae 9, colchicines tablets 3.5, Radix Rehmanniae Preparata 7, Rhizoma Chuanxiong 18, Rhizoma Corydalis 13, Herba Asari 12, Rhizoma Drynariae 7, orotic acid.
The preparation method of the compositions of above-mentioned treatment hyperosteogeny, step is:
(1) dry clean for Carapax et Plastrum Testudinis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 110 mesh sieves stand-by;
(2) Rhizoma Cibotii, Radix Clematidis, Cortex Acanthopancis and Herba Asari white vinegar are soaked 13 hours, steam 35 minutes, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 110 mesh sieves for subsequent use for pulverization altogether;
(3) Herba Taraxaci, Olibanum, Rhizoma Homalomenae, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Rhizoma Corydalis and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry fast 7 minutes, sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) calcium gluconate tablet, colchicines tablets and the vitamin B slender roll of medicated paper or gauze are pulverized; add calcium gluconate tablet, colchicines tablets and FA boiled water doubly; soak 9 hours; add step (1)-(3) gained smalls; little fire is heated to boiling; stir; change slow fire boiling 45 hours; leave standstill 15 hours; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
typical case two:liu XX, man, 48 years old, both legs arthralgia 8 years, was diagnosed as both legs hyperosteogeny, many hospitalizes, and bad when taking a lot of medicine fashion, doctor advised takes the present composition.
Use and coordinate embodiment 4 resulting composition, giving a Chinese medicine of the present invention month symptom and obviously alleviate, treat 3 months transference cures, self-induction is fully recovered.
embodiment 5the compositions for the treatment of hyperosteogeny, each crude drug is as follows, is weight portion (getting 30g for every part): Carapax et Plastrum Testudinis 3, calcium gluconate tablet 3, Rhizoma Cibotii 5, Radix Clematidis 5, Cortex Acanthopancis 6, Herba Taraxaci 13, Olibanum 10, Rhizoma Homalomenae 7.5, colchicines tablets 3, Radix Rehmanniae Preparata 6, Rhizoma Chuanxiong 15, Rhizoma Corydalis 10, Herba Asari 11, Rhizoma Drynariae 6, vitamin B12.
The preparation method of the compositions of above-mentioned treatment hyperosteogeny, step is:
(1) dry clean for Carapax et Plastrum Testudinis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 100 mesh sieves stand-by;
(2) Rhizoma Cibotii, Radix Clematidis, Cortex Acanthopancis and Herba Asari white vinegar are soaked 10 hours, steam 30 minutes, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 100 mesh sieves for subsequent use for pulverization altogether;
(3) Herba Taraxaci, Olibanum, Rhizoma Homalomenae, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Rhizoma Corydalis and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry fast 6 minutes, sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) calcium gluconate tablet, colchicines tablets and the vitamin B slender roll of medicated paper or gauze are pulverized; add calcium gluconate tablet, colchicines tablets and vitamin B7 .5 boiled water doubly; soak 8 hours; add step (1)-(3) gained smalls; little fire is heated to boiling; stir; change slow fire boiling 40 hours; leave standstill 14 hours; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
experimental example (embodiment 5 resulting composition):in order to verify the effect of the present composition, we have extracted 400 patients in 4 hospitals and have carried out the experiment of medicine, test group 200 people, matched group 200 people, experimental group uses embodiment 5 resulting composition, and matched group uses the medicine of other treatment treatment hyperosteogeny.Inclusion criteria: through being diagnosed as the pain patients that femur head necrosis causes, the pain clinical symptoms having femur head necrosis to cause is one or more.Using method: for making the present invention reach optimum therapeuticing effect, three get oral medicine 3-5ml of the present invention, warm water delivery service after the meal, and external smearing ointment spreads upon affected part, wraps with bundle, and using once before sleep every night, 7 days is a course for the treatment of.Curative effect situation criterion: 1, cure, after using this product, malaise symptoms disappears completely; 2, effective, after using this product, malaise symptoms alleviates or partial disappearance; 3, invalid, after using this product, malaise symptoms is unchanged.We have carried out accurate statistics and mathematical analysis to experimental data.Specific experiment result is as following table:
Table 1: two groups of Clinical efficacy comparison [example] tables 1
Self-induction symptom and emotion changes result are as table 2:
Table 2:
Prove through clinical trial, the present composition is in treatment hyperosteogeny, and effective percentage is 98%, and thoroughly can remove old complaint, treating both the principal and secondary aspects of a disease, makes the recovery from illness that patient is real; And any burden can not be caused to the health of patient.Present composition instant effect, can reach the object alleviating rapidly patient's misery, and relapse rate is low, is a kind of composition and method of making the same of the treatment for the treatment of safely and effectively hyperosteogeny.
The composition and method of making the same for the treatment of hyperosteogeny, wherein Rhizoma Chuanxiong, Herba Asari do monarch, and ministerial drug is Herba Taraxaci, Olibanum and Rhizoma Corydalis, and remaining is adjuvant drug; Monarch drug carries attending effectiveness in the present invention, all has effect of benefiting qi and nourishing blood, relaxing muscles and tendons to promote blood circulation, strong muscle key bone-specific drug hyperosteogeny; Ministerial drug is the medicine that auxiliary monarch drug strengthens the main disease for the treatment of and main symptom; Adjuvant drug treatment is held concurrently disease, slows down the strong of monarch drug and ministerial drug; Medicine is made to play a part guiding drug.
Claims (10)
1. treat the compositions of hyperosteogeny, it is characterized in that: each crude drug is as follows, is weight portion: Carapax et Plastrum Testudinis 1-5, calcium gluconate tablet 2-4, Rhizoma Cibotii 3-7, Radix Clematidis 2-6, Cortex Acanthopancis 4-8, Herba Taraxaci 10-15, Olibanum 5-15, Rhizoma Homalomenae 5-10, colchicines tablets 2-4, Radix Rehmanniae Preparata 4-8, Rhizoma Chuanxiong 10-20, Rhizoma Corydalis 5-15, Herba Asari 6-16, Rhizoma Drynariae 3-9, vitaminB10-14.
2. the compositions for the treatment of hyperosteogeny according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Carapax et Plastrum Testudinis 2-4, calcium gluconate tablet 2.5-3.5, Rhizoma Cibotii 4-6, Radix Clematidis 4-6, Cortex Acanthopancis 5-7, Herba Taraxaci 11-14, Olibanum 8-13, Rhizoma Homalomenae 6-9, colchicines tablets 2.5-3.5, Radix Rehmanniae Preparata 5-7, Rhizoma Chuanxiong 13-18, Rhizoma Corydalis 8-13, Herba Asari 10-12, Rhizoma Drynariae 5-7, VB11-13.
3. the compositions for the treatment of hyperosteogeny according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Carapax et Plastrum Testudinis 3, calcium gluconate tablet 3, Rhizoma Cibotii 5, Radix Clematidis 5, Cortex Acanthopancis 6, Herba Taraxaci 13, Olibanum 10, Rhizoma Homalomenae 7.5, colchicines tablets 3, Radix Rehmanniae Preparata 6, Rhizoma Chuanxiong 15, Rhizoma Corydalis 10, Herba Asari 11, Rhizoma Drynariae 6, vitamin B12.
4. the preparation method of the compositions of the treatment hyperosteogeny according to any one of claim 1-3, is characterized in that: step is as follows:
(1) dry clean for Carapax et Plastrum Testudinis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 80-120 mesh sieve stand-by;
(2) Rhizoma Cibotii, Radix Clematidis, Cortex Acanthopancis and Herba Asari white vinegar is soaked 5-15 hour, steam 20-40 minute, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 80-120 mesh sieve for subsequent use for pulverization altogether;
(3) Herba Taraxaci, Olibanum, Rhizoma Homalomenae, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Rhizoma Corydalis and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry 4-8 minute fast, and sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) calcium gluconate tablet, colchicines tablets and the vitamin B slender roll of medicated paper or gauze are pulverized; add the boiled water of calcium gluconate tablet, colchicines tablets and vitamin B5-10 times; soak 5-10 hour; add step (1)-(3) gained smalls; little fire is heated to boiling; stir; change slow fire boiling 30-50 hour; leave standstill 12-16 hour; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
5. the preparation method of compositions according to claim 4, is characterized in that: step (1) smalls crosses 90-110 mesh sieve stand-by (preferred, it is stand-by that smalls crosses 100 mesh sieves).
6. the preparation method of compositions according to claim 4, it is characterized in that: Rhizoma Cibotii, Radix Clematidis, Cortex Acanthopancis and Herba Asari white vinegar soak 8-13 hour (preferred, Rhizoma Cibotii, Radix Clematidis, Cortex Acanthopancis and Herba Asari white vinegar are soaked 10 hours) by step (2).
7. the preparation method of compositions according to claim 4, is characterized in that: step (2) steams 25-35 minute (preferred, to steam 30 minutes).
8. the preparation method of compositions according to claim 4, is characterized in that: step (3) drops into the crude drug cut, and stir-fry 5-7 minute (preferred, to drop into the crude drug cut, stir-fry fast 6 minutes) fast.
9. the preparation method of compositions according to claim 4, it is characterized in that: step (4) adds the boiled water of calcium gluconate tablet, colchicines tablets and vitamin B6-9 times, soak 6-9 hour (preferably, add calcium gluconate tablet, colchicines tablets and vitamin B7 .5 boiled water doubly, soak 8 hours).
10. the preparation method of compositions according to claim 4, it is characterized in that: step (4) little fire is heated to boiling, stir, change slow fire boiling 35-45 hour, (preferred, little fire is heated to boiling, stirs to leave standstill 13-15 hour, change slow fire boiling 40 hours, leave standstill 14 hours).
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105250896A (en) * | 2015-10-15 | 2016-01-20 | 王仕珍 | Hyperostosis medicinal liquor and preparation method thereof |
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Application publication date: 20150513 |