CN104606237A - Preparation method of gecko powder without peculiar smell - Google Patents
Preparation method of gecko powder without peculiar smell Download PDFInfo
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- CN104606237A CN104606237A CN201510096291.3A CN201510096291A CN104606237A CN 104606237 A CN104606237 A CN 104606237A CN 201510096291 A CN201510096291 A CN 201510096291A CN 104606237 A CN104606237 A CN 104606237A
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- house liyard
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Abstract
The invention provides a preparation method of gecko powder without a peculiar smell. The preparation method comprises the following steps: adding milk powder, and crushing. The prepared gecko powder is small in peculiar smell during oral administration and high in patient compliance.
Description
Invention field
The present invention relates to medicine, particularly a kind of preparation method of free from extraneous odour house liyard powder, belong to medical art.
Background technology
Gekko Swinhonis is also known as Gekko Swinhonis, Gekko Swinhonis etc.For Gekkonidae animal is all without the drying of web Gekko Swinhonis (Gekko swinho-nis Gunther) or many nevuss Gekko Swinhonis (Gekko japonicus Cdumerit et Bi) and other several Gekko Swinhonis, make the dosage forms such as ball, loose, cream to be used as medicine more, be widely used in clinical various diseases, particularly have definite curative effect to difficult miscellaneous diseases such as Several Kinds of Malignancy, tuberculosis, osteomyelitis.
Gekko Swinhonis generally season in autumn in summer two catch oven dry be used as medicine.Gekko Swinhonis is because making a living with episite, and thus abdomen is built-in with insect bodies such as a large amount of indigested mosquitos and flies, easily causes be with microbial reproduction, corrodes its internal organs, thus causes Gekko Swinhonis often with abnormal foul smell, makes us nauseating after news, takes orally and easily causes vomiting.Directly affect the compliance of patient.A kind of method improving Gekko Swinhonis taste is provided, very necessary.
Summary of the invention
The object of this invention is to provide a kind of preparation method of free from extraneous odour house liyard powder.
The object of the present invention is achieved like this:
A preparation method for free from extraneous odour house liyard powder, is characterized in that: add milk powder and pulverize.
The preparation method of a kind of free from extraneous odour house liyard powder of the present invention, is characterized in that: the amount adding milk powder is more than 0.1 times by weight.
The preparation method of a kind of free from extraneous odour house liyard powder of the present invention, is characterized in that: the amount adding milk powder is 0.5-2 times by weight.
The preparation method of a kind of free from extraneous odour house liyard powder of the present invention, is characterized in that: the amount adding milk powder is 1 times by weight.
The preparation method of a kind of free from extraneous odour house liyard powder of the present invention, is characterized in that: replace with and add milk powder in house liyard powder.
So far the present invention is completed.The preparation method of a kind of free from extraneous odour house liyard powder of the present invention, under the prerequisite keeping the original curative effect of Gekko Swinhonis, oral abnormal flavour is little, and mouthfeel is good, and the compliance of patient is high.
Below by test example, usefulness of the present invention is described.Test example is intended to further illustrate beneficial effect of the present invention, but not restriction of the present invention.
House liyard powder mouthfeel prepared by test example one, distinct methods compares
1, with a collection of dry Gekko Swinhonis, will prepare by the following method respectively.
1) directly pulverize;
2) add milk powder to pulverize: add 0.1 times of milk powder, pulverize.
2, mouthfeel compares
Be made up of 10 people and appraise group through discussion, everyone warm water for oral use direct pulverizing of mixing well and add the house liyard powder that milk powder pulverizes respectively, evaluates the mouthfeel mouthfeel such as " very well ", " better ", " can accept ", " poor ", " very poor ".Evaluation result is in table 1
House liyard powder mouthfeel powder mouthfeel prepared by table 1 distinct methods compares
Very well | Better | Can accept | Poor | Very poor | |
Add milk powder to pulverize | 0 people | 2 people | 8 people | 0 people | 0 people |
Direct pulverizing | 0 people | 0 people | 0 people | 1 people | 9 people |
Result shows, and Gekko Swinhonis adds milk powder and pulverizes, and oral abnormal flavour is little, and mouthfeel is good.
The house liyard powder of test example two, distinct methods processing is tested the tumor-inhibiting action of S180 tumor-bearing mice
S180 tumor-bearing mice belly cavity tumor cell is inoculated in mouse peritoneal continuous passage, aseptic aspiration 7d mouse peritoneal in age tumor cell, adds tumor cell to 4 × 10 in normal saline adjustment cell suspension
6/ ml, then in every mice right oxter injection 0.2ml tumor cell suspension.After 24h, at random mice is divided into 3 groups: model group, add milk powder pulverizing group and directly pulverizing group, often organizes 10.Body weight zero difference between each group.Model group is with normal saline 0.2 ml/d gavage.Administration group gavage gives the house liyard powder mixed well with normal saline, and every mouse stomach amount is that 0.2 ml/d(contains house liyard powder 0.2g, and the house liyard powder of oven dry with milk presses Gekko Swinhonis content meter).After successive administration 10d, within the 11st day, crane one and put to death mice, shell tumor, weigh, calculate tumour inhibiting rate.
The average tumor of suppression ratio (%)=(model group average tumor weight-experimental group average tumor weight)/model group heavy × 100% of implanted solid tumor growth.The results are shown in Table 2.
The house liyard powder of table 2 distinct methods processing is to the comparison of mice tumour inhibiting rate
Model group | Add milk powder pulverizing group | Direct pulverizing group | |
Average tumor heavy (g) | 2.42±1.09 | 1.07±0.64 | 1.07±0.68 |
Tumour inhibiting rate (%) | 0 | 55.79 | 55.79 |
Result shows, the house liyard powder adding milk powder pulverizing is suitable with the house liyard powder tumor-inhibiting action directly pulverized.Explanation adds milk powder pulverizing and maintains original curative effect.
Detailed description of the invention
embodiment 1
Dry Gekko Swinhonis 2kg, adds milk powder 0.2kg, mixing, pulverizes, obtains abnormal flavour Geko powder.
embodiment 2
Dry Gekko Swinhonis 2kg, adds milk powder 4kg, mixing, pulverizes, obtains abnormal flavour Geko powder.
embodiment 3
Dry Gekko Swinhonis 2kg, adds milk powder 1kg, mixing, pulverizes, obtains abnormal flavour Geko powder.
embodiment 4
Dry Gekko Swinhonis 2kg, adds milk powder 6kg, mixing, pulverizes, obtains abnormal flavour Geko powder.
embodiment 5
Dry Gekko Swinhonis 2kg, adds milk powder 0.5kg, glucose 0.5kgg, mixing, pulverizes, obtains abnormal flavour Geko powder.
embodiment 6
Dry Gekko Swinhonis 2kg, adds milk powder 15kg, glucose 30g, saccharin sodium 3g, vanillin 1g, mixing, pulverizes, obtains abnormal flavour Geko powder.
embodiment 7
Dry Gekko Swinhonis 2kg, adds milk powder 20kg, saccharin sodium 3g, vanillin 2g, mixing, pulverizes, obtains abnormal flavour Geko powder.
embodiment 8
House liyard powder 2kg, milk powder 20kg, saccharin sodium 3g, vanillin 2g, mixing, obtains abnormal flavour Geko powder.
embodiment 9
House liyard powder 2kg, milk powder 0.2kg, mixing, obtains abnormal flavour Geko powder.
Claims (5)
1. a preparation method for free from extraneous odour house liyard powder, is characterized in that: add milk powder and pulverize.
2. the preparation method of a kind of free from extraneous odour house liyard powder according to claim 1, is characterized in that: the amount entering powder with milk is more than 0.1 times by weight.
3. according to the preparation method of a kind of free from extraneous odour house liyard powder of claim 1 or claim 2, it is characterized in that: the amount entering powder with milk is 0.5-2 times by weight.
4., according to the preparation method of a kind of free from extraneous odour house liyard powder of claim 1 or claim 2 or claim 3, it is characterized in that: the amount adding milk powder is 1 times by weight.
5. the preparation method of a kind of free from extraneous odour house liyard powder according to claim 1, is characterized in that: replace with and add milk powder in house liyard powder.
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CN201510096291.3A CN104606237A (en) | 2015-03-05 | 2015-03-05 | Preparation method of gecko powder without peculiar smell |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101167749A (en) * | 2007-11-09 | 2008-04-30 | 重庆医药工业研究院有限责任公司 | Preparing method for improving toad venom taste |
CN101884406A (en) * | 2009-05-12 | 2010-11-17 | 刘凤鸣 | Taste-masking technology by taking milk powder as taste-masking agent and application thereof |
CN103891895A (en) * | 2012-12-31 | 2014-07-02 | 内蒙古伊利实业集团股份有限公司 | Liquid dairy product containing earthworm protein and preparation method of liquid dairy product |
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2015
- 2015-03-05 CN CN201510096291.3A patent/CN104606237A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101167749A (en) * | 2007-11-09 | 2008-04-30 | 重庆医药工业研究院有限责任公司 | Preparing method for improving toad venom taste |
CN101884406A (en) * | 2009-05-12 | 2010-11-17 | 刘凤鸣 | Taste-masking technology by taking milk powder as taste-masking agent and application thereof |
CN103891895A (en) * | 2012-12-31 | 2014-07-02 | 内蒙古伊利实业集团股份有限公司 | Liquid dairy product containing earthworm protein and preparation method of liquid dairy product |
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Application publication date: 20150513 |