CN104587031B - Traditional Chinese medicine composition for treating women raynaud disease - Google Patents
Traditional Chinese medicine composition for treating women raynaud disease Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating women raynaud disease. The traditional Chinese medicine composition is prepared from the raw materials as follows: oxhide gelatin, tortoise shell, mulberry, eclipta, cassia twig, root of kudzu vine, rose, semen litchi, corydalis amabilis, loofah sponge, spina date seed, valerian and sea buckthorn. Aiming at the special pathogenesis of women raynaud disease, the traditional Chinese medicine composition for treating women raynaud disease has obvious therapeutic effect and is a special medicine for treating women raynaud disease. The traditional Chinese medicine composition decoction for treating women raynaud disease is adopted for treating 38 patients, after the treatment for 2 months, 19 patients are recovered, 10 patients are obviously treated, 6 patients get better, 3 patients are not treated, and the total effective rate is 92.1%.
Description
Technical field
The present invention relates to Chinese medicine sciemtifec and technical sphere, more particularly to a kind of Chinese medicine composition for treating women Raynaud's disease.
Background technology
Raynaud's disease, also known as " acra arteriospasm disease ", is the acra arteriolar spasm caused by nervus vasculairs dysfunction
Disease.Fall ill with catch cold, many factors such as emotional change and endocrine disturbance it is relevant.Because pathomechanism is unclear, treatment is general
Using the medicine for alleviating arteriospasm.This disease is more common in the women between 20-40 Sui, and some patient symptoms are aggravated in the menstrual period,
The gestational period mitigates.With " warming channel and expelling cold " for big method, and women is cloudy soft body to Chinese traditional treatment Raynaud's disease, gas have a surplus and blood not
The scattered gas consumption blood trouble of foot, excessively temperature, easily causes excessive menstruation etc..With reference to physiology characteristics, research and development treatment women Raynaud's disease
Special-purpose medicaments have important clinical significance.
The content of the invention
It is an object of the invention to overcome in the prior art not for the rational Chinese medicine group of compatibility of women Raynaud's disease
Compound deficiency and put forward, that is, a kind of Chinese medicine composition for treating women Raynaud's disease is provided.
In order to realize foregoing invention purpose, the invention provides following technical scheme：
A kind of Chinese medicine composition for treating women Raynaud's disease, the medicament being made up of the bulk drug of following mass ratio：
6~12 parts of oxhide gelatin, 15~25 parts of tortoise plastron, 8~12 parts of mulberry fruit, 8~12 parts of eclipta, 4~6 parts of cassia twig, the root of kudzu vine
12~18 parts, 4~8 parts of rose, 4~8 parts of semen litchi, 8~12 parts of decumbent corydalis tuber, 6~10 parts of luffa, spina date seed 12~18
Part, 4~6 parts of valerian, 6~10 parts of sea-buckthorn.
Herbal pharmacology effect of the present invention is as follows：
Oxhide gelatin：It is sweet, flat, return lung, large intestine channel.Nourshing Yin and drynsessmoistening prescription, nourishing blood and hemoslasis, activating blood circulation and reducing swelling, removing toxic substances.Oxhide gelatin has benefit
Blood, antifatigue, protection gastric mucosa effect.
Tortoise plastron：It is sweet, cold, return kidney, liver, the heart channel of Hang-Shaoyin.Enriching yin, checking exuberance of yang, replenishing kidney and strengthening bone, blood-nourishing bushing.It is " cloudy that tortoise plastron can improve animal
It is empty " card pathology animal functional state, it is allowed to recover normal；Immunologic function can be strengthened；Effect with bidirectional modulation DNA synthetic ratios
Should；Have it is antipyretic, enrich blood, sedation；Still there is anticoagulation, increase coronary flow and improve the effect such as hypoxia-bearing capability.
Mulberry fruit：It is sweet, sour, cold, return liver and kidney channel.Nourishing yin and supplementing blood, fluid dryness.Mulberry fruit has moderate to promote lymphocyte transformation
Effect；T cell can be promoted ripe, so that the T cell function of aging is restored；Have to young mouse humoral immune function
Facilitation；There is facilitation to the growth of grain system progenitor cells；It reduces erythrocyte membrane NA+-K+The activity of-ATP enzyme, it may be possible to
One of action principle of its enriching yin；It prevents the leukopenic effect of caused by cyclophosphamide.
Eclipta：It is sweet, sour, cold, return liver and kidney channel.It is nourishing liver and kidney, cooling blood and hemostasis.Eclipta has raising body non-specific
Property immunologic function effect, oxygen radical can be eliminated to suppress 5- lipoxygenase, protect chromosome, liver protection promotes liver cell again
It is raw, increase coronary blood flow, life of the extension mouse under normobaric hypoxia improves depositing in the case of hypobaric hypoxia mouse
Motility rate；And have calmness, ease pain, promote hair growth, act on hair blackening, hemostasis, antibacterial, anti-Amoeba, anticancer etc..
Cassia twig：Pungent, sweet, temperature, the thoughts of returning home, lung, bladder warp.Sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi.Cassia twig have cooling,
Antipyretic, bacteriostasis；The also effect such as stomach invigorating, alleviation cramps of gastrointestinal tract, diuresis, cardiac stimulant, analgesia, calmness, anticonvulsion.
The root of kudzu vine：It is sweet, pungent, cool, returns spleen, stomach.Expelling pathogenic factors from muscles and skin is brought down a fever, promoting eruption, is promoted the production of body fluid to quench thirst, Shengyang Zhixie.The root of kudzu vine can expand hat
Arteries and veins blood vessel and the cerebrovascular, increase CF and cerebral blood flow (CBF), and reduce myocardial oxygen consumption increases oxygen supply；Can directly expand
Blood vessel, declines peripheral resistance, and has obvious antihypertensive effect, can preferably alleviate " item is tight " symptom of hypertensive patient；Can also change
Kind microcirculation, improves local micro- CBF, suppresses platelet aggregation；The root of kudzu vine has extensive beta-receptor retardation；The root of kudzu vine also has
There is obvious refrigeration function, and have slight hypoglycemic effect.
Rose：Sweet, slight bitter, temperature, Return liver, the spleen channel.Soothing liver-qi stagnation, promoting blood circulation and stopping pain.Rose has promotion choleresis to make
With；There is certain protective effect to experimental animal models myocardial ischemia.
Semen litchi：Pungent, slight bitter, temperature, Return liver, stomach.Promoting the circulation of qi dissipating bind, eliminating cold to stop pain.Semen litchi have hypoglycemic, Adjust-blood lipid and
Antioxidation, can reduce T-CHOL（TC）And triglycerides（TG）；The radical damage caused by ALX can be resisted, improves anti-
Oxidizing ferment SOD activity；There is the mutagenesis of confrontation salmonella typhimurium；There is suppression to make to hepatitis b virus s antigen
With.
Decumbent corydalis tuber：Hardship, micro-pungent, temperature, return liver warp.Promoting blood circulation and stopping pain, channels sootheing and network vessel quickening, dispelling wind and eliminating dampness.Decumbent corydalis tuber have analgesia and
Sedation；Coronary flow can be increased, peripheral vascular is expanded, reduced blood pressure；Platelet aggregation can be suppressed, to antithrombus formation；
There is lax and spasmolysis to uterine smooth muscle and intestinal smooth muscle.
Luffa：It is sweet, flat, return lung, stomach, Liver Channel.Eradicates wind, dredging collateral, promoting blood circulation.Luffa has obvious analgesia, calm and anti-
Inflammation effect.
Spina date seed：It is sweet, sour, flat, the thoughts of returning home, liver, gallbladder channel.Nourishing heart benefit liver, calms the nerves, arrest sweating.
Spina date seed has tranquilizing soporific and antiarrhythmic effect, and the CNS inhibition of barbiturate can be cooperateed with to make
With；Also anticonvulsion, analgesia, body-temp. reducing, antihypertensive effect；Additionally, spina date seed also has reducing blood lipid, anti anoxia, antitumor, suppression blood
Platelet is assembled, and enhancing immunologic function and excited uterus act on.
Valerian：Pungent, sweet, temperature, the thoughts of returning home, Liver Channel.Calm the nerves qi-regulating, promoting blood circulation and stopping pain.Valerian has tranquilizing effect, can substantially expand
Coronary artery blood vessel is opened, improves myocardial ischemia, reduce myocardial oxygen consumption, anti-arrhythmia.
Sea-buckthorn：Sweet, sour, temperature, returns spleen, stomach, lung, the heart channel of Hang-Shaoyin.Reinforcing spleen to promote digestion, cough-relieving apophlegmatic, promoting blood circulation.Sea-buckthorn has the improvement heart
Flesh microcirculation, reduce myocardial oxygen consumption, anti-angiogenic hardening, anti-inflammatory etc. are acted on；Can with antifatigue, reducing blood lipid, radioresistance, anti-burst
Ulcer, liver protection and enhancing immunologic function.
The Raynaud's disease traditional Chinese medical science is referred to as " vessle-Bi symptom-complex ", " blood-arthralgia ", " arthritis " etc., more because catching cold, emotional change induce.Middle treatment
Treat with " warming channel and expelling cold " as big method, and woman with blood for this, with liver as congenital, gas is had a surplus and blood is not enough, and the excessively warm gas consumption that dissipates is hindered
Blood, easily causes excessive menstruation etc..In addition, the essence of kidney controlling congenital essence, The heart controls mental activities, with reference to physiology characteristics, this sick interpretation of the cause, onset and process of an illness
It is blood and essence asthenia, irritability stasis, the mind is lost and supported.The present invention is using oxhide gelatin, tortoise plastron, mulberry fruit, eclipta nourishing yin and nourishing blood；Cassia twig
Take the meaning of " junior fire supporting vital QI ", it is intended that fire is mended slightly with yang-energy in the kidney for inspiring virtual loss, with growth-promoting the moon blood；Root of kudzu vine rising Yang is stimulated the menstrual flow；Rose
Rare flower, semen litchi soothing liver-qi stagnation；Decumbent corydalis tuber, luffa are promoting blood circulation and removing obstruction in channels；Spina date seed, valerian nourishing heart benefit liver, vital energy regualting and blood circulation-promoting；Sea-buckthorn
Reinforcing spleen to promote digestion, promoting blood circulation.All medicines share, nourishing yin and nourishing blood, dispersing stagnated hepatoqi, mental-tranquilization.
Preferably, the medicine that the Chinese medicine composition of the treatment women Raynaud's disease is made up of the bulk drug of following mass ratio
Agent：
8~10 parts of oxhide gelatin, 18~22 parts of tortoise plastron, 9~11 parts of mulberry fruit, 9~11 parts of eclipta, 4~6 parts of cassia twig, the root of kudzu vine
14~16 parts, 5~7 parts of rose, 5~7 parts of semen litchi, 9~11 parts of decumbent corydalis tuber, 7~9 parts of luffa, 14~16 parts of spina date seed,
4~6 parts of valerian, 7~9 parts of sea-buckthorn.
It is further preferred that bulk drug system of the Chinese medicine composition of the treatment women Raynaud's disease by following mass ratio
Into medicament：
9 parts of oxhide gelatin, 20 parts of tortoise plastron, 10 parts of mulberry fruit, 10 parts of eclipta, 5 parts of cassia twig, 15 parts of the root of kudzu vine, 6 parts of rose, litchi
6 parts of core of branch, 10 parts of decumbent corydalis tuber, 8 parts of luffa, 15 parts of spina date seed, 5 parts of valerian, 8 parts of sea-buckthorn.
The Chinese medicine composition of the treatment women Raynaud's disease can be prepared into any normal using existing Chinese medicine preparation technique
Rule oral preparations, for example, can obtain water decoction by said components using decocting, can also be by other existing Chinese medicine preparation skills
The Chinese medicine composition of the treatment women Raynaud's disease is prepared piece agent, water-honeyed pill, capsule, powder, paste, oral by art
Liquid, granule.
Compared with prior art, beneficial effects of the present invention
The Chinese medicine composition of the treatment women Raynaud's disease that the present invention is provided, suits women Raynaud's disease special onset machine
System, therapeutic effect is the special-purpose medicaments for treating women Raynaud's disease substantially.
A kind of Chinese medicine composition for treating women Raynaud's disease, clinical efficacy is summarized
1 physical data
38 female patients, 18~42 years old age, average age 31.2 years old, the course of disease 1~2.4 year, average course of disease 1.1 years.
2 diagnostic criteria
Reference《Clinical disease diagnosis are according to healing improvement standard》（The Ministry of Public Health of The General Logistics Department of PLA is clinical
Medical diagnosis on disease is according to healing improvement standard Beijing：People's Medical Officer Press, 1987：6701.）The diagnostic criteria of middle Raynaud's disease：
1. it is apt to occur in 20~40 years old introverted women.2. Raynaud's phenomenon breaking-out is induced when cold or excited（Acra skin face
Color turns livid purple by pale, then becomes flush）, the duration is roughly as 15~30min, a few patients start to occur it is livid purple and without grey
The white stage, or pale is afterwards to switch to flush, and without livid purple.3. bilateral involvement.4. radial artery, pulsation of foot dorsal artery are normal.5. without
Necrosis is showed, or the subcutaneous necrosis for being confined to finger tip only late occurs.6. other systemic diseases are excluded.
3 treatment methods
9 grams of oxhide gelatin, 20 grams of tortoise plastron, 10 grams of mulberry fruit, 10 grams of eclipta, 5 grams of cassia twig, 15 grams of the root of kudzu vine, 6 grams of rose, litchi
6 grams of core of branch, 10 grams of decumbent corydalis tuber, 8 grams of luffa, 15 grams of spina date seed, 5 grams of valerian, 8 grams of sea-buckthorn.According to conventional Chinese medicine preparation technology
Water decoction is made, everyone one portion per day.
4 treatment results
4.1 criterions of therapeutical effect：1. fully recover：Clinical symptoms are wholly absent, and environmental stimuli no longer induces Raynaud's phenomenon breaking-out.②
It is effective：Clinical symptom disappearance, environmental stimuli causes finger once in a while（Toe）Send out cool, but without color change.3. take a turn for the better：Clinical symptoms are basic
Disappear, substantially mitigate before environmental stimuli occasionally has Raynaud's phenomenon to break out, but symptom is relatively treated with sign.4. it is invalid：Symptom and sign
Without improvement.
4.2 results：Treated through 2 months, fully recovered 19, effective 10, taken a turn for the better 6, invalid 3, total effective rate 92.1%.
Specific embodiment
With reference to specific embodiment, the present invention is described in further detail.The scope of the above-mentioned theme of the present invention is only
It is limited to following examples, that is, requires nothing more than protection treatment women Raynaud's disease.
Embodiment 1
A kind of Chinese medicine composition for treating women Raynaud's disease, is by 12 grams of oxhide gelatin, 25 grams of tortoise plastron, 12 grams of mulberry fruit, ink
12 grams of non-irrigated lotus, 6 grams of cassia twig, 18 grams of the root of kudzu vine, 8 grams of rose, 8 grams of semen litchi, 12 grams of decumbent corydalis tuber, 10 grams of luffa, spina date seed 18
Gram, 6 grams of valerian, 10 grams of sea-buckthorn, be made water decoction according to conventional Chinese medicine preparation technology, everyone one portion per day.
Embodiment 2
A kind of Chinese medicine composition for treating women Raynaud's disease, is by 10 grams of oxhide gelatin, 22 grams of tortoise plastron, 11 grams of mulberry fruit, ink
11 grams of non-irrigated lotus, 6 grams of cassia twig, 16 grams of the root of kudzu vine, 7 grams of rose, 7 grams of semen litchi, 11 grams of decumbent corydalis tuber, 9 grams of luffa, spina date seed 16
Gram, 6 grams of valerian, 9 grams of sea-buckthorn, be made water decoction according to conventional Chinese medicine preparation technology, everyone one portion per day.
Embodiment 3
A kind of Chinese medicine composition for treating women Raynaud's disease, is by 9 grams of oxhide gelatin, 20 grams of tortoise plastron, 10 grams of mulberry fruit, ink drought
10 grams of lotus, 5 grams of cassia twig, 15 grams of the root of kudzu vine, 6 grams of rose, 6 grams of semen litchi, 10 grams of decumbent corydalis tuber, 8 grams of luffa, 15 grams of spina date seed,
5 grams of valerian, 8 grams of sea-buckthorn, are made water decoction, everyone one portion per day according to conventional Chinese medicine preparation technology.
Embodiment 4
A kind of Chinese medicine composition for treating women Raynaud's disease, is by 8 grams of oxhide gelatin, 18 grams of tortoise plastron, 9 grams of mulberry fruit, ink drought
9 grams of lotus, 4 grams of cassia twig, 14 grams of the root of kudzu vine, 5 grams of rose, 5 grams of semen litchi, 9 grams of decumbent corydalis tuber, 7 grams of luffa, 14 grams of spina date seed, figured silk fabrics
Careless 4 grams, 7 grams of sea-buckthorn, are made water decoction, everyone one portion per day according to conventional Chinese medicine preparation technology.
Embodiment 5
A kind of Chinese medicine composition for treating women Raynaud's disease, is by 6 grams of oxhide gelatin, 15 grams of tortoise plastron, 8 grams of mulberry fruit, ink drought
8 grams of lotus, 4 grams of cassia twig, 12 grams of the root of kudzu vine, 4 grams of rose, 4 grams of semen litchi, 8 grams of decumbent corydalis tuber, 6 grams of luffa, 12 grams of spina date seed, figured silk fabrics
Careless 4 grams, 6 grams of sea-buckthorn, are made water decoction, everyone one portion per day according to conventional Chinese medicine preparation technology.
Claims (3)
1. a kind of Chinese medicine composition for treating women Raynaud's disease, it is characterised in that be made up of the bulk drug of following mass ratio
Medicament：
6~12 parts of oxhide gelatin, 15~25 parts of tortoise plastron, 8~12 parts of mulberry fruit, 8~12 parts of eclipta, 4~6 parts of cassia twig, the root of kudzu vine 12~
18 parts, 4~8 parts of rose, 4~8 parts of semen litchi, 8~12 parts of decumbent corydalis tuber, 6~10 parts of luffa, 12~18 parts of spina date seed, figured silk fabrics
Careless 4~6 parts, 6~10 parts of sea-buckthorn.
2. the Chinese medicine composition of women Raynaud's disease is treated as claimed in claim 1, it is characterised in that by following mass ratio
The medicament that is made of bulk drug：
8~10 parts of oxhide gelatin, 18~22 parts of tortoise plastron, 9~11 parts of mulberry fruit, 9~11 parts of eclipta, 4~6 parts of cassia twig, the root of kudzu vine 14~
16 parts, 5~7 parts of rose, 5~7 parts of semen litchi, 9~11 parts of decumbent corydalis tuber, 7~9 parts of luffa, 14~16 parts of spina date seed, valerian
4~6 parts, 7~9 parts of sea-buckthorn.
3. the Chinese medicine composition of women Raynaud's disease is treated as claimed in claim 1, it is characterised in that by following mass ratio
The medicament that is made of bulk drug：
9 parts of oxhide gelatin, 20 parts of tortoise plastron, 10 parts of mulberry fruit, 10 parts of eclipta, 5 parts of cassia twig, 15 parts of the root of kudzu vine, 6 parts of rose, semen litchi 6
Part, 10 parts of decumbent corydalis tuber, 8 parts of luffa, 15 parts of spina date seed, 5 parts of valerian, 8 parts of sea-buckthorn.
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