CN104510987A - Chinese medicinal mixture for treatment of paranoidschizophrenia - Google Patents
Chinese medicinal mixture for treatment of paranoidschizophrenia Download PDFInfo
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- CN104510987A CN104510987A CN201410758526.6A CN201410758526A CN104510987A CN 104510987 A CN104510987 A CN 104510987A CN 201410758526 A CN201410758526 A CN 201410758526A CN 104510987 A CN104510987 A CN 104510987A
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Classifications
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract
The invention provides a Chinese medicinal mixture for treatment of paranoidschizophrenia. The Chinese medicinal mixture is characterized by being prepared from the following herbal materials by weight: 10-30 parts of radix bupleuri, 5-15 parts of Scutellaria baicalensis, 5-15 parts of cassia twig, 10-20 parts of radix paeoniae rubra, 10-20 parts of white peony root, 10-20 parts of prepared pinellia tuber, 10-20 parts of dried tangerine peel, 5-15 parts of fructus aurantii, 10-20 parts of bamboo shavings, 10-20 parts of Curcuma aromatic, 15-30 parts of poria with hostwood, 10-20 parts of acorus gramineus, 10-20 parts of polygala root, 10-20 parts of Armeniaca mume, 5-15 parts of pseudostellaria root, 15-30 parts of albizia bark, and 5-15 parts of Radix Glycyrrhizae Preparata. The Chinese medicinal mixture provided by the invention is prepared from pure natural herbal materials, and has the advantages of definite curative effect, treatment of both symptoms and root causes, low relapse rate after cure, small toxic and side effect and the like in treatment of paranoidschizophrenia.
Description
Technical field:
The present invention relates to technical field of Chinese medicine, particularly a kind of Traditional Chinese drug mixture for the treatment of paranoea.
Background technology:
Paranoea and paranoid schizophrenia are schizoid one, to vainly hope the disease with hallucination.Distinguish according to content, vain hope can comprise: delusion of persecution, association vain hope, religions delusion, arrogant vain hope, politics vain hope etc.Hallucination then according to the difference of consciousness, can be distinguished into optical illusion, audition hallucination, olfactory sensation hallucination, sense of taste hallucination, sense of touch hallucination, body hallucination etc.General this disease morbidity is more late, and patient has often had certain social status, school work, vocational ability, so symptom during morbidity and hebephrenic schizophrenia are by comparison, compare at last and conforms with social norm.Such as hebephrenic schizophrenia patient may eat stool, console oneself in the presence of all, and paranoid schizophrenia patient has this kind of phenomenon hardly.The situation that social function is degenerated is lighter at last with it paranoid schizophrenia patient.Mostly treatment at present for assertive evidence is to adopt the western medicines such as olanzapine, clozapine, amisulpride, risperidone, sulpiride, but it is large to drug dependence to there is patient, and the organ of drugs on patients has the problems such as certain toxic and side effects.
Summary of the invention:
The present invention be exactly provide a kind for the treatment of for paranoea to have determined curative effect, treating both the principal and secondary aspects of a disease to overcome deficiency of the prior art, to control recurrence rate after healing low, and the Traditional Chinese drug mixture that toxic and side effects is little.
The invention provides following technical scheme:
Treat a Traditional Chinese drug mixture for paranoea, it is characterized in that being made up of the raw material of Chinese medicine of following weight proportion: Radix Bupleuri 10-30 part, Radix Scutellariae 5-15 part, Ramulus Cinnamomi 5-15 part, Radix Paeoniae Rubra 10-20 part, Radix Paeoniae Alba 10-20 part, Rhizoma Pinelliae Preparatum 10-20 part, Pericarpium Citri Reticulatae 10-20 part, Fructus Aurantii 5-15 part, Caulis Bambusae In Taenia 10-20 part, Radix Curcumae 10-20 part, Poria cum Radix Pini 15-30 part, Rhizoma Acori Graminei 10-20 part, Radix Polygalae 10-20 part, FLOS MUME 10-20 part, Radix Pseudostellariae 5-15 part, Cortex Albiziae 15-30 part, Radix Glycyrrhizae Preparata 5-15 part.
Formula is preferably:
Radix Bupleuri 10 parts, Radix Scutellariae 5 parts, Ramulus Cinnamomi 5 parts, Radix Paeoniae Rubra 10 parts, the Radix Paeoniae Alba 10 parts, Rhizoma Pinelliae Preparatum 10 parts, Pericarpium Citri Reticulatae 10 parts, Fructus Aurantii 6 parts, Caulis Bambusae In Taenia 10 parts, Radix Curcumae 10 parts, Poria cum Radix Pini 20 parts, Rhizoma Acori Graminei 10 parts, Radix Polygalae 10 parts, FLOS MUME 10 parts, Radix Pseudostellariae 8 parts, Cortex Albiziae 20 parts, Radix Glycyrrhizae Preparata 6 parts.
Preparation method:
Get above-mentioned all Chinese medicine by weight ratio after screening, eluriate, removing slag, first get Pericarpium Citri Reticulatae, remaining medicinal residues are decocted 3 times after extracting volatile oil by FLOS MUME together with other raw material of Chinese medicine, after merging gained decoction liquor is condensed into the thick paste of 1.15-1.30, add volatile oil again, high-speed stirred is after 30 minutes, be ground into 200-400 order fine powder after again thick paste being condensed into dry extract, gained is Traditional Chinese drug mixture medicated powder of the present invention, makes the pill of 2 grams every after adding refined honey.
Method of administration:
Each morning, noon and afternoon respectively take medicine once, and each serving using 2-4 grain, taking continuously two weeks is a course for the treatment of.
The drug effect forming each raw material of Chinese medicine of the present invention is described as follows:
Radix Bupleuri: bitter in the mouth, cold nature.Return liver, gallbladder meridian.There is reconciling superficies and interior, soothing the liver, the effects such as yang invigorating.Be usually used in cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, the diseases such as proctoptosis.This product also has that antipyretic, antiinflammatory, phagocytic function strengthen, Natural killer activity strengthens, improve special viral antibody titre, improve lymphocyte turns core rate, improves the effects such as skin delayed hypersensitivity reaction, anti-liver injury and Antiradiation injury.
Radix Scutellariae: bitter in the mouth, cold in nature.Return lung, gallbladder, spleen, large intestine, small intestine meridian.There is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Be usually used in hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, the diseases such as frequent fetal movement.Research shows: this product also has antiinflammatory antiallergic action, antimicrobial, antipyretic, blood pressure lowering, diuresis, has the effects such as significantly suppression to intestinal tube.Particularly the clinical antibiotic property of Radix Scutellariae is better than Rhizoma Coptidis, and does not develop immunity to drugs.
Ramulus Cinnamomi: acrid in the mouth, sweet, warm in nature.GUIXIN, lung, urinary bladder channel.There is diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, the effects such as dispersing cold for relieving pain.Be usually used in anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, the diseases such as renal mass.This product also has blood vessel dilating, regulates blood circulation, antipyretic, analgesia, calmness, convulsion, antiinflammatory, antiallergic, the effect such as antibacterial.
Radix Paeoniae Rubra: bitter in the mouth, cold nature.Return Liver Channel.There is clearing away heat and cooling blood, the effects such as eliminating stasis to stop pain.Be usually used in maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, injury from falling down, the diseases such as carbuncle skin infection.This product also has anti-thrombosis function, antiplatelet aggregative activity, blood fat reducing and arteriosclerosis effect, increases myocardial alimentary blood flow, anoxia enduring, expansion Pulmonary Vascular, reduce pulmonary artery pressure and pulmonary vascular resistance, increase cardiac output, the effect such as improve the effect such as right heart function and hemorheological property, antitumor action and protect the liver.
The Radix Paeoniae Alba: bitter in the mouth, acid, cold nature.Return liver, spleen channel.There is suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, the effects such as astringing YIN to stop sweating.Be usually used in headache dizzy, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, the diseases such as night sweat.This product coronary artery dilator, reduces blood pressure, and d-cachou extract and progallin A have antithrombotic and antiplatelet aggregative activity; Caused hepatic injury has obvious protective effect; There is inhibitory action to intestinal tube and stomach in place motion, significantly resist the uterine contraction that oxytocin causes; Mouse writhing can be suppressed, shout, hot plate reaction, suppress writhing response to have synergism to morphine, and can resist that pentylenetetrazole is caused faints from fear.
Rhizoma Pinelliae Preparatum: generally refer to that half summer grade Rhizoma Zingiberis Recens, Alumen use after concocting, be called Rhizoma Pinelliae Preparatum.Acrid in the mouth, warm in nature.Return spleen, stomach, lung meridian.There is the effects such as drying dampness to eliminate phlegm.Be usually used in abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, the diseases such as syncope due to accumulation of phlegm headache.
Pericarpium Citri Reticulatae: bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.There is regulating qi-flowing for strengthening spleen, the effects such as drying dampness to eliminate phlegm.Be usually used in fullness in the epigastrium and chest, lack of appetite and vomiting, the diseases such as cough with copious phlegm.The volatile oil of this product is irritant to eliminate the phlegm and the effect of expansion bronchus, has gentle stimulation to gastrointestinal smooth muscle, can facilitating digestion liquid secretion and eliminate intestinal pneumatosis.Fresh goods decoct and alcohol extract have excitation to heart, and larger dose has inhibitory action; Have slight vasoconstrictive effect, intravenous injection has rapid boosting, and repetitively administered also has no drug resistance; Methylhesperidin makes coronary flow increase, and coronary resistance reduces, and blood pressure reduces the effect that heart rate reduces.Hesperidin can reduce cholesterol, inhibition test ulcer.Reduce the effects such as capillary permeability.
Fructus Aurantii: bitter in the mouth, pungent, sour, warm in nature.Return spleen, stomach warp.There is regulating the flow of QI to ease the stomach, the effects such as the stagnant relieving distension of row.Be usually used in the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official such as to prolapse the disease.This product also has increases coronary flow and renal hemodynamic blood, diuresis, antiallergic action, have the effect such as significant increase cerebral blood flow and reduction cerebral vascular resistance.
Caulis Bambusae In Taenia: sweet in the mouth, cold nature.Attach to the lung and stomach meridians.Have removing heat-phlegm, the effect such as relieve restlessness and prevent vomiting.Be usually used in phlegm-heat cough, expectorant held under the arm by gallbladder fire, and dysphoria with smothery sensation is vomitted, and eye is lost in palpitation with fear, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, the diseases such as frequent fetal movement.This product all has the stronger effect such as antibacterial to Staphylococcus albus, bacillus subtilis, escherichia coli and Bacillus typhi etc.
Radix Curcumae: acrid in the mouth, hardship, cold in nature.Return liver, the heart, lung meridian.There is regulating qi to disperse stagnation, heart fire-clearing upset-relieving, the effects such as promoting the function of the gallbladder to alleviate jaundice.Be usually used in amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, the diseases such as epilepsy is gone mad, jaundice dark coloured urine.This product has antifungal, strengthens reticuloendothelial system Activation Activity, reduces plasma fibrinogen, reduces the content of cholesterol and triglyceride and increase the effects such as bile secretion.
Poria cum Radix Pini: sweet in the mouth, light, property is put down.GUIXIN, spleen channel.There is mind calming, calm the nerves, the effects such as diuretic.Be usually used in palpitation with fear of having a guilty conscience, forgetful, insomnia, infantile convulsion, the diseases such as dysuria.This product has strong sedation.
Rhizoma Acori Graminei: acrid in the mouth, hardship, warm in nature.GUIXIN, stomach warp.There is removing dampness appetizing, eliminating phlegm of having one's ideas straightened out, the effects such as refreshment Fructus Alpiniae Oxyphyllae.Be usually used in gastral cavity painful abdominal mass not hungry, a mouthful dysentery of keeping silent, coma epilepsy, the diseases such as forgetful deafness.This product has convulsion, hypnosis, memory reinforcing, can increase the effects such as coronary flow, antifungal and antitussive.
Radix Polygalae: bitter in the mouth, pungent, warm in nature.GUIXIN, kidney, lung meridian.There is Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, the effects such as detumescence.Be usually used in the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, the diseases such as breast swell and pain.This product have eliminate the phlegm, calmness, convulsion, edema, diuresis, antibacterial, mutation, haemolysis and improve the effects such as intelligence.
FLOS MUME: bitter in the mouth, micro-sweet, property is put down.Return liver, stomach, lung meridian.Have dispersing the stagnated live-QI to relieve the stagnation of QI, appetizing rises the effects such as Tianjin.Be usually used in distending pain in the chest and hypochondrium, stomachache, dyspepsia, neurasthenia, the diseases such as globus hystericus.
Radix Pseudostellariae: sweet in the mouth, micro-hardship, property is put down.Return spleen, lung meridian.There is replenishing QI to invigorate the spleen, the effects such as promoting the production of body fluid for nourishing the lung.Be usually used in insufficiency of the spleen body tired, inappetence, weak after being ill, deficiency of both vital energy and Yin, the diseases such as spontaneous perspiration is thirsty, dryness of the lung dry cough.This product has adaptive significances to body, can enhancing body to the defence capability of various destructive stimulus.In addition, the substance metabolism in human body can also be strengthened.
Cortex Albiziae: sweet in the mouth, property is put down.GUIXIN, liver, lung meridian.There is resolving stagnation for tranquilization, the effects such as promoting blood circulation and detumescence.Be usually used in irritability, melancholy insomnia, lung abscess skin ulcer swells, and falls and flutters grieved grade for disease.This product has the effects such as antiallergic, antifertility, antitumor.
Radix Glycyrrhizae Preparata: sweet in the mouth, property is put down.Return stomach, lung, spleen channel.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effects such as coordinating the actions of various ingredients in a prescription.Be usually used in weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, the disease such as strong.This product has removing toxic substances, eliminates the phlegm, pain relieving, spasmolytic, anticancer, conditioner body immunity function, arrhythmia, blood fat reducing, anti-
atherosclerosis, anticoagulant, the pharmacological action such as antitumor.In addition, this product is also good at the toxicity removing Radix Aconiti Lateralis Preparata.
Advantage of the present invention:
The present invention adopts the treatment of making for paranoea of natural Chinese medicines raw material to have determined curative effect, treating both the principal and secondary aspects of a disease, it is low to control recurrence rate after healing, and the advantage such as toxic and side effects is little.
Detailed description of the invention:
Embodiment 1:
Treat a Traditional Chinese drug mixture for paranoea, it is characterized in that being made up of the raw material of Chinese medicine of following weight proportion: Radix Bupleuri 10 parts, Radix Scutellariae 5 parts, Ramulus Cinnamomi 5 parts, Radix Paeoniae Rubra 10 parts, the Radix Paeoniae Alba 10 parts, Rhizoma Pinelliae Preparatum 10 parts, Pericarpium Citri Reticulatae 10 parts, Fructus Aurantii 6 parts, Caulis Bambusae In Taenia 10 parts, Radix Curcumae 10 parts, Poria cum Radix Pini 20 parts, Rhizoma Acori Graminei 10 parts, Radix Polygalae 10 parts, FLOS MUME 10 parts, Radix Pseudostellariae 8 parts, Cortex Albiziae 20 parts, Radix Glycyrrhizae Preparata 6 parts.
Embodiment 2:
Treat a Traditional Chinese drug mixture for paranoea, it is characterized in that being made up of the raw material of Chinese medicine of following weight proportion: Radix Bupleuri 15 parts, Radix Scutellariae 10 parts, Ramulus Cinnamomi 10 parts, Radix Paeoniae Rubra 15 parts, the Radix Paeoniae Alba 15 parts, Rhizoma Pinelliae Preparatum 15 parts, Pericarpium Citri Reticulatae 18 parts, Fructus Aurantii 10 parts, Caulis Bambusae In Taenia 15 parts, Radix Curcumae 15 parts, Poria cum Radix Pini 15 parts, Rhizoma Acori Graminei 15 parts, Radix Polygalae 10 parts, FLOS MUME 12 parts, Radix Pseudostellariae 10 parts, Cortex Albiziae 15 parts, Radix Glycyrrhizae Preparata 10 parts.
Embodiment 3:
Treat a Traditional Chinese drug mixture for paranoea, it is characterized in that being made up of the raw material of Chinese medicine of following weight proportion: Radix Bupleuri 30 parts, Radix Scutellariae 15 parts, Ramulus Cinnamomi 15 parts, Radix Paeoniae Rubra 20 parts, the Radix Paeoniae Alba 20 parts, Rhizoma Pinelliae Preparatum 20 parts, Pericarpium Citri Reticulatae 20 parts, Fructus Aurantii 15 parts, Caulis Bambusae In Taenia 20 parts, Radix Curcumae 20 parts, Poria cum Radix Pini 30 parts, Rhizoma Acori Graminei 20 parts, Radix Polygalae 20 parts, FLOS MUME 20 parts, Radix Pseudostellariae 15 parts, Cortex Albiziae 30 parts, Radix Glycyrrhizae Preparata 15 parts.
Embodiment 1-3 all adopts following preparation and method of administration:
Get above-mentioned all Chinese medicine by weight ratio after screening, eluriate, removing slag, first get Pericarpium Citri Reticulatae, remaining medicinal residues are decocted 3 times after extracting volatile oil by FLOS MUME together with other raw material of Chinese medicine, after merging gained decoction liquor is condensed into the thick paste of 1.15-1.30, add volatile oil again, high-speed stirred is after 30 minutes, be ground into 200-400 order fine powder after again thick paste being condensed into dry extract, gained is Traditional Chinese drug mixture medicated powder of the present invention, makes the pill of 2 grams every after adding refined honey.
Each morning, noon and afternoon respectively take medicine once, and each serving using 2-4 grain, taking continuously two weeks is a course for the treatment of.
Claims (3)
1. treat a Traditional Chinese drug mixture for paranoea, it is characterized in that being made up of the raw material of Chinese medicine of following weight proportion: Radix Bupleuri 10-30 part, Radix Scutellariae 5-15 part, Ramulus Cinnamomi 5-15 part, Radix Paeoniae Rubra 10-20 part, Radix Paeoniae Alba 10-20 part, Rhizoma Pinelliae Preparatum 10-20 part, Pericarpium Citri Reticulatae 10-20 part, Fructus Aurantii 5-15 part, Caulis Bambusae In Taenia 10-20 part, Radix Curcumae 10-20 part, Poria cum Radix Pini 15-30 part, Rhizoma Acori Graminei 10-20 part, Radix Polygalae 10-20 part, FLOS MUME 10-20 part, Radix Pseudostellariae 5-15 part, Cortex Albiziae 15-30 part, Radix Glycyrrhizae Preparata 5-15 part.
2., according to a kind of Traditional Chinese drug mixture for the treatment of paranoea described in claim 1, it is characterized in that being made up of the raw material of Chinese medicine of following weight proportion: Radix Bupleuri 10 parts, Radix Scutellariae 5 parts, Ramulus Cinnamomi 5 parts, Radix Paeoniae Rubra 10 parts, the Radix Paeoniae Alba 10 parts, Rhizoma Pinelliae Preparatum 10 parts, Pericarpium Citri Reticulatae 10 parts, Fructus Aurantii 6 parts, Caulis Bambusae In Taenia 10 parts, Radix Curcumae 10 parts, Poria cum Radix Pini 20 parts, Rhizoma Acori Graminei 10 parts, Radix Polygalae 10 parts, FLOS MUME 10 parts, Radix Pseudostellariae 8 parts, Cortex Albiziae 20 parts, Radix Glycyrrhizae Preparata 6 parts.
3. treat the preparation method of the Traditional Chinese drug mixture of paranoea for one kind, it is characterized in that comprising following concrete steps: get above-mentioned all Chinese medicine by weight ratio through screening, eluriate, after removing slag, first get Pericarpium Citri Reticulatae, remaining medicinal residues are decocted 3 times after extracting volatile oil by FLOS MUME together with other raw material of Chinese medicine, after merging gained decoction liquor is condensed into the thick paste of 1.15-1.30, add volatile oil again, high-speed stirred is after 30 minutes, 200-400 order fine powder is ground into after again thick paste being condensed into dry extract, gained is Traditional Chinese drug mixture medicated powder of the present invention, the pill of 2 grams every is made after adding refined honey.
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| CN106110028A (en) * | 2016-07-29 | 2016-11-16 | 车丽娜 | A kind of Chinese medicine preparation for treating paranoea and preparation method |
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