CN104586999A - Medicament for treating breast cancer - Google Patents

Medicament for treating breast cancer Download PDF

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Publication number
CN104586999A
CN104586999A CN201510078353.8A CN201510078353A CN104586999A CN 104586999 A CN104586999 A CN 104586999A CN 201510078353 A CN201510078353 A CN 201510078353A CN 104586999 A CN104586999 A CN 104586999A
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parts
herba
cortex
caulis
medicament
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CN201510078353.8A
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刘文莉
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Abstract

The invention relates to a medicament for treating breast cancer. The medicament is prepared from the following raw materials in parts by weight: 20 to 50 parts of rhododendron microphyton franch, 10 to 30 parts of tinospora sinensis merr, 10 to 20 parts of marsdenia tenacissima, 10 to 20 parts of white mulberry root-barks, 10 to 20 parts of soroseris gillii, 10 to 20 parts of tiarella polyphylla, 10 to 30 parts of climbing oldenlandia, 10 to 20 parts of pakchoi seedling, 10 to 30 parts of common fibraurea stems, 1 to 10 parts of parnassia palustris, 10 to 20 parts of Japanese pachysandra herbs, 1 to 20 parts of grewia lantsangensis hu, 10 to 20 parts of fructus cnidii, 1 to 10 parts of hops, 10 to 30 parts of oxalis corymbosa, 1 to 10 parts of rhizoma bergeniae scopulosae, 10 to 20 parts of common nepenthes, 1 to 20 parts of luzula campestris, 10 to 30 parts of bunge hackberry barks or stems, 1 to 10 parts of lilac, 10 to 20 parts of rhizoma panacis japonici and 1 to 10 parts of licorice. The medicament for treating breast cancer is reasonable in formula, and has the characteristics of definite therapeutic effects, high safety, high convenience, no toxic or side effects and low cost.

Description

A kind of medicament for the treatment of breast carcinoma
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of medicament for the treatment of breast carcinoma.
Background technology
Breast carcinoma is one of malignant tumor of harm WomanHealth, first of all kinds of Cancer Mortality of women and mortality rate.Breast carcinoma adult female morbidity about 1%, about has 7.9 ten thousand new cases to occur every year, and in increasing trend year by year, therefore the prevention of breast carcinoma and Therapy study have become instant task.Traditional operation and the selectivity of Radiotherapy chemotherapy process to pathological tissues and normal structure poor, various complication and sequela can be caused, and cause body QI and blood consumption wound, make the life quality of patient and behavior state all poor, therefore there is certain limitation.Chinese medicine role in breast cancer treatment is more and more irreplaceable.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of breast carcinoma.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of breast carcinoma, it is made up by weight of following bulk drugs: Radix Rhododendri 20-50 part, Herba Lycopodii 10-30 part, Caulis Marsdeniae Tenacissimae 10-20 part, Cortex Mori 10-20 part, thin,tough silk hair chrysanthemum 10-20 part, Herba tiarellae polyphyllae 10-20 part, Herba Hedyotis scandentis 10-30 part, Plantula Brassicae chinensis 10-20 part, Caulis Fibraureae 10-30 part, Herba parnassiae 1-10 part, Herba Pachysandrae Terminalis 10-20 part, prairie fire rope 1-20 part, Fructus Cnidii 10-20 part, Flos lupuli (Flos Humuli Lupuli) 1-10 part, Herba oxalidis corymbosae 10-30 part, Rhizoma Bergeniae scopulosae 1-10 part, Herba nepenthis 10-20 part, Cor Cervi grass 1-20 part, Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 10-30 part, Syringa oblata Lindl. 1-10 part, black brave seven 10-20 parts and Radix Glycyrrhizae 1-10 part.
Preferably, the medicament of described treatment breast carcinoma is made up by weight of following bulk drugs: Radix Rhododendri 30 parts, Herba Lycopodii 20 parts, Caulis Marsdeniae Tenacissimae 12 parts, Cortex Mori 15 parts, thin,tough silk hair chrysanthemum 12 parts, Herba tiarellae polyphyllae 12 parts, Herba Hedyotis scandentis 20 parts, Plantula Brassicae chinensis 15 parts, Caulis Fibraureae 20 parts, Herba parnassiae 6 parts, Herba Pachysandrae Terminalis 15 parts, 10 parts, prairie fire rope, Fructus Cnidii 15 parts, Flos lupuli (Flos Humuli Lupuli) 6 parts, Herba oxalidis corymbosae 20 parts, 8 parts, Rhizoma Bergeniae scopulosae, Herba nepenthis 15 parts, Cor Cervi grass 10 parts, Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 20 parts, Syringa oblata Lindl. 6 parts, black brave 7 12 parts and 8 parts, Radix Glycyrrhizae.
Preferably, described medicament can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, patch or ointment.
The present invention also provides the purposes of compositions in the medicine of preparation treatment breast carcinoma, described compositions is made up by weight of following bulk drugs: Radix Rhododendri 20-50 part, Herba Lycopodii 10-30 part, Caulis Marsdeniae Tenacissimae 10-20 part, Cortex Mori 10-20 part, thin,tough silk hair chrysanthemum 10-20 part, Herba tiarellae polyphyllae 10-20 part, Herba Hedyotis scandentis 10-30 part, Plantula Brassicae chinensis 10-20 part, Caulis Fibraureae 10-30 part, Herba parnassiae 1-10 part, Herba Pachysandrae Terminalis 10-20 part, prairie fire rope 1-20 part, Fructus Cnidii 10-20 part, Flos lupuli (Flos Humuli Lupuli) 1-10 part, Herba oxalidis corymbosae 10-30 part, Rhizoma Bergeniae scopulosae 1-10 part, Herba nepenthis 10-20 part, Cor Cervi grass 1-20 part, Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 10-30 part, Syringa oblata Lindl. 1-10 part, black brave seven 10-20 parts and Radix Glycyrrhizae 1-10 part.
Preferably, described compositions is made up by weight of following bulk drugs: Radix Rhododendri 30 parts, Herba Lycopodii 20 parts, Caulis Marsdeniae Tenacissimae 12 parts, Cortex Mori 15 parts, thin,tough silk hair chrysanthemum 12 parts, Herba tiarellae polyphyllae 12 parts, Herba Hedyotis scandentis 20 parts, Plantula Brassicae chinensis 15 parts, Caulis Fibraureae 20 parts, Herba parnassiae 6 parts, Herba Pachysandrae Terminalis 15 parts, 10 parts, prairie fire rope, Fructus Cnidii 15 parts, Flos lupuli (Flos Humuli Lupuli) 6 parts, Herba oxalidis corymbosae 20 parts, 8 parts, Rhizoma Bergeniae scopulosae, Herba nepenthis 15 parts, Cor Cervi grass 10 parts, Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 20 parts, Syringa oblata Lindl. 6 parts, black brave 7 12 parts and 8 parts, Radix Glycyrrhizae.
More preferably, described medicine can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, patch or ointment.
Generally acknowledged that " organic conception ", " determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs ", " compound recipe use ", " compound compatibility medication is as used military forces " are the traditional Chinese medical science the most effective most scientific several large advantages at present, wherein " compound compatibility medication is as used military forces " is the original theory of Chinese medicine of very science.The tight compatibility that in traditional Chinese medical science prescription, each medicine is all linked with one another as arrayed troops for battle is that it is better than the effective means of Western medicine formula.Tcm prescription theory is thought, each prescription, not only need to select the appropriate compatibility of suitable medicament according to etiology and pathogenesis, also should meet the basic structure of prescription simultaneously, the i.e. prescription compatibility theory of " monarch, minister, help, make ", the prescription compatibility of so-called " monarch, minister, help, make " is exactly that it is based upon the scientific matching on the comprehensive judgement basis of disease pathogenesis.In medical side by too many levels, Mutiple Targets Integrate adjustment biological mechanism, can to obtain than Western medicine more lastingly, the more therapeutic effect that has no side effect of green natural, and this curative effect be based upon the above-mentioned traditional Chinese medical science tradition original theory accurate instruction on, the present invention just have followed this principle.
In the present invention, Radix Rhododendri, Herba Lycopodii are monarch drug; Caulis Marsdeniae Tenacissimae, Cortex Mori, thin,tough silk hair chrysanthemum, Herba tiarellae polyphyllae, Herba Hedyotis scandentis, Plantula Brassicae chinensis are ministerial drug; Caulis Fibraureae, Herba parnassiae, Herba Pachysandrae Terminalis, prairie fire rope, Fructus Cnidii, Flos lupuli (Flos Humuli Lupuli), Herba oxalidis corymbosae, Rhizoma Bergeniae scopulosae, Herba nepenthis, Cor Cervi grass, Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane), Syringa oblata Lindl., black brave seven are adjuvant drug; Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, plays the effect making medicine in the compositions of the present invention.All medicines are harmonious in the present invention, reasonable recipe, have determined curative effect, safe ready, have no side effect, cheap feature.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment ointment of the present invention
Take Radix Rhododendri 300 grams, Herba Lycopodii 200 grams, Caulis Marsdeniae Tenacissimae 120 grams, Cortex Mori 150 grams, thin,tough silk hair chrysanthemum 120 grams, Herba tiarellae polyphyllae 120 grams, Herba Hedyotis scandentis 200 grams, Plantula Brassicae chinensis 150 grams, Caulis Fibraureae 200 grams, Herba parnassiae 60 grams, Herba Pachysandrae Terminalis 150 grams, 100 grams, prairie fire rope, Fructus Cnidii 150 grams, Flos lupuli (Flos Humuli Lupuli) 60 grams, Herba oxalidis corymbosae 200 grams, 80 grams, Rhizoma Bergeniae scopulosae, Herba nepenthis 150 grams, Cor Cervi grass 100 grams, Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 200 grams, Syringa oblata Lindl. 60 grams, black brave 7 120 grams and 80 grams, Radix Glycyrrhizae, add 8 liters, water, heating 3 hours under the condition of backflow, filter, relative density 1.20 at filtrate being concentrated into 55 DEG C, ZLPG6-10 spray dryer (Jiangsu Fan Qun drying equipment factory) is used to be 115 DEG C in inlet temperature, infusion pump rotating speed is carry out spraying dry under the condition of 25r/min, thus obtain dried powder, lanoline 1500 grams is added in above-mentioned powder, be stirred into paste, obtain ointment of the present invention.
Experimental example
Diagnostic criteria
Diagnostic criteria is formulated in diagnostic criteria with reference to the 8th fascicle " breast carcinoma " in " Chinese common cancer diagnosis and treatment specification " that Ministry of Public Health is compiled.Be specially clinically: touch lump in breast, matter is hard, touch less than obvious lump in air spots or breast, but pathology or cytolgical examination have found cancerous cell, all can be diagnosed as breast carcinoma.
Selector closes female patient 46 example of standard of stating, wherein left breast cancer 21 example, right breast carcinoma 25 example, the age be 35-59 year, average 45 years old.
The ointment using embodiment to prepare is treated, and every day 3 times, spreads upon on the ill breast of lump equably by the ointment of 50 grams at every turn, continuously treatment 2 months.
Efficacy assessment standard
Chemotherapeutic efficacy standard is drafted with reference to national breast carcinoma meeting in 1987:
1. disappear (CR) entirely: all cancer seen of looking into disappear completely, and osteolytic lesion is whole calcification on x-ray;
2. partial disappearance (PR): can measure pathological changes and reduce 50% (products of 2 maximum perpendicular diameters of axle), occurs without new focus simultaneously, but does not require that all focuses all belong to PR.
3. stable without becoming (S): tumor regression < 50%, or increase < 25%.
4. worsen (PD): some focus reduces < 50%, some focus increases > 25% simultaneously, or all focuses increase, or has new focus to occur.
Therapeutic outcome
Through treatment, find that the tumor of all patients all disappears, follow up a case by regular visits to and do not recur for 1 year, all meet the standard entirely disappeared.Do not find obvious untoward reaction over the course for the treatment of,
Model case
Hu, 49 years old, patient's health check-up found lump in breast, and without obvious pain, also aperiodicity change, quality is hard as rock, and mobility is poor.Be right breast carcinoma through hospital diagnosis, patient's emaciated physique, shortness of breath and palpitation, dim complexion, fatigue and weakness, soreness of the waist and knees.Because of not for being treated surgically, turning the traditional Chinese medical science and curing.Disease is seen through thing disorderly, and premenstrual distending pain of the breast, lump in breast is hard, pale tongue, white and thin fur, stringy and thready pulse.The ointment using embodiment to prepare is treated, and every day 3 times, spreads upon on the ill breast of lump equably by the ointment of 50 grams at every turn, continuously treatment 2 months.Patient's chest lump disappears, and all diseases are all removed, and examination in hospital is without difference.Follow up a case by regular visits to 1 year, health is good.
Yang, 51 years old, right breast outward top found a lump about 4 × 4cm, and matter firmly, not bitterly, rough, surrounding is irregular, and hospital diagnosis is breast carcinoma.Disease sees left arm distending pain, sometimes slightly feels numb, shallow complexion, tired mind, thin and greasy fur, stringy pulse.The ointment using embodiment to prepare is treated, and every day 3 times, spreads upon on the ill breast of lump equably by the ointment of 50 grams at every turn, continuously treatment 2 months.Patient's chest lump disappears, and all diseases are all removed, and examination in hospital is without difference.Follow up a case by regular visits to 1 year, health is good.

Claims (6)

1. treat the medicament of breast carcinoma for one kind, it is characterized in that, it is made up by weight of following bulk drugs: Radix Rhododendri 20-50 part, Herba Lycopodii 10-30 part, Caulis Marsdeniae Tenacissimae 10-20 part, Cortex Mori 10-20 part, thin,tough silk hair chrysanthemum 10-20 part, Herba tiarellae polyphyllae 10-20 part, Herba Hedyotis scandentis 10-30 part, Plantula Brassicae chinensis 10-20 part, Caulis Fibraureae 10-30 part, Herba parnassiae 1-10 part, Herba Pachysandrae Terminalis 10-20 part, prairie fire rope 1-20 part, Fructus Cnidii 10-20 part, Flos lupuli (Flos Humuli Lupuli) 1-10 part, Herba oxalidis corymbosae 10-30 part, Rhizoma Bergeniae scopulosae 1-10 part, Herba nepenthis 10-20 part, Cor Cervi grass 1-20 part, Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 10-30 part, Syringa oblata Lindl. 1-10 part, black brave seven 10-20 parts and Radix Glycyrrhizae 1-10 part.
2. the medicament for the treatment of breast carcinoma according to claim 1, it is characterized in that, it is made up by weight of following bulk drugs: Radix Rhododendri 30 parts, Herba Lycopodii 20 parts, Caulis Marsdeniae Tenacissimae 12 parts, Cortex Mori 15 parts, thin,tough silk hair chrysanthemum 12 parts, Herba tiarellae polyphyllae 12 parts, Herba Hedyotis scandentis 20 parts, Plantula Brassicae chinensis 15 parts, Caulis Fibraureae 20 parts, Herba parnassiae 6 parts, Herba Pachysandrae Terminalis 15 parts, 10 parts, prairie fire rope, Fructus Cnidii 15 parts, Flos lupuli (Flos Humuli Lupuli) 6 parts, Herba oxalidis corymbosae 20 parts, 8 parts, Rhizoma Bergeniae scopulosae, Herba nepenthis 15 parts, Cor Cervi grass 10 parts, Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 20 parts, Syringa oblata Lindl. 6 parts, black brave 7 12 parts and 8 parts, Radix Glycyrrhizae.
3. the medicament for the treatment of breast carcinoma according to claim 2, is characterized in that, described medicament can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, patch or ointment.
4. the purposes of compositions in the medicine of preparation treatment breast carcinoma, it is characterized in that, described compositions is made up by weight of following bulk drugs: Radix Rhododendri 20-50 part, Herba Lycopodii 10-30 part, Caulis Marsdeniae Tenacissimae 10-20 part, Cortex Mori 10-20 part, thin,tough silk hair chrysanthemum 10-20 part, Herba tiarellae polyphyllae 10-20 part, Herba Hedyotis scandentis 10-30 part, Plantula Brassicae chinensis 10-20 part, Caulis Fibraureae 10-30 part, Herba parnassiae 1-10 part, Herba Pachysandrae Terminalis 10-20 part, prairie fire rope 1-20 part, Fructus Cnidii 10-20 part, Flos lupuli (Flos Humuli Lupuli) 1-10 part, Herba oxalidis corymbosae 10-30 part, Rhizoma Bergeniae scopulosae 1-10 part, Herba nepenthis 10-20 part, Cor Cervi grass 1-20 part, Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 10-30 part, Syringa oblata Lindl. 1-10 part, black brave seven 10-20 parts and Radix Glycyrrhizae 1-10 part.
5. purposes according to claim 4, it is characterized in that, described compositions is made up by weight of following bulk drugs: Radix Rhododendri 30 parts, Herba Lycopodii 20 parts, Caulis Marsdeniae Tenacissimae 12 parts, Cortex Mori 15 parts, thin,tough silk hair chrysanthemum 12 parts, Herba tiarellae polyphyllae 12 parts, Herba Hedyotis scandentis 20 parts, Plantula Brassicae chinensis 15 parts, Caulis Fibraureae 20 parts, Herba parnassiae 6 parts, Herba Pachysandrae Terminalis 15 parts, 10 parts, prairie fire rope, Fructus Cnidii 15 parts, Flos lupuli (Flos Humuli Lupuli) 6 parts, Herba oxalidis corymbosae 20 parts, 8 parts, Rhizoma Bergeniae scopulosae, Herba nepenthis 15 parts, Cor Cervi grass 10 parts, Cortex celtis bungeanae (Cortex seu Caulis Celtis Bungeane) 20 parts, Syringa oblata Lindl. 6 parts, black brave 7 12 parts and 8 parts, Radix Glycyrrhizae.
6. purposes according to claim 5, is characterized in that, described medicine can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, patch or ointment.
CN201510078353.8A 2015-02-13 2015-02-13 Medicament for treating breast cancer Pending CN104586999A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106822666A (en) * 2017-04-13 2017-06-13 李桂兰 A kind of medicine for treating breast cancer and its preparation method and application
CN113876826A (en) * 2021-09-24 2022-01-04 武汉科技大学 Brachypodium delavayi extract and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1358531A (en) * 2001-11-28 2002-07-17 王允奎 Medicine for treating cancer
CN101125178A (en) * 2007-08-27 2008-02-20 毕哲全 Traditional Chinese medicine for treating tumor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1358531A (en) * 2001-11-28 2002-07-17 王允奎 Medicine for treating cancer
CN101125178A (en) * 2007-08-27 2008-02-20 毕哲全 Traditional Chinese medicine for treating tumor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
刘朝霞等: "焦中华治疗乳腺癌经验", 《辽宁中医杂志》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106822666A (en) * 2017-04-13 2017-06-13 李桂兰 A kind of medicine for treating breast cancer and its preparation method and application
CN113876826A (en) * 2021-09-24 2022-01-04 武汉科技大学 Brachypodium delavayi extract and preparation method and application thereof

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Application publication date: 20150506