CN103800505B - A kind of Chinese medicine composition treating breast carcinoma and its preparation method and application - Google Patents
A kind of Chinese medicine composition treating breast carcinoma and its preparation method and application Download PDFInfo
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- CN103800505B CN103800505B CN201410070739.XA CN201410070739A CN103800505B CN 103800505 B CN103800505 B CN 103800505B CN 201410070739 A CN201410070739 A CN 201410070739A CN 103800505 B CN103800505 B CN 103800505B
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- 238000002360 preparation method Methods 0.000 title claims description 12
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Abstract
The invention discloses a kind of Chinese medicine composition treating breast carcinoma, belong to the field of Chinese medicines.This Chinese medicine composition is made up of Cortex Phellodendri l0 30 parts, Herba Cistanches l5 25 parts, Spica Prunellae 5 15 parts, Caulis Akebiae l0 30 parts, Scolopendra 5 15 parts, Squama Manis 5 15 parts, Radix Angelicae Sinensis 15 30 parts, Rhizoma Chuanxiong l0 20 parts, Fructus Corni l0 20 parts.Each medicine synergism in the Chinese medicine composition of the present invention, the effect for the treatment of breast carcinoma is notable, and its effective percentage is up to 95%, and cure rate is up to 75%, and controls difficulty in relapse after healing.
Description
Technical field
The invention belongs to field of medicaments, be specifically related to a kind of Chinese medicine preparation treating breast carcinoma and preparation method thereof.
Background technology
Breast carcinoma refer to breast ductal epithelial cells under the effect of various inside and outside carcinogenic factors, cell loses normal characteristic and paraplasm, so that exceeding the limit of self-regeneration and the disease of canceration occurring.Breast carcinoma is one of modal malignant tumor of women, and according to statistics, sickness rate accounts for the 7-10% of the various malignant tumor of whole body, is that one has a strong impact on the most life-threatening disease of women's physical and mental health.Its performance the earliest is to suffer from breast the most circular, the oval or difform little lump of single-shot, form occur, and quality is the most harder, indefinite border；A few patients can have distending pain, dull pain.The morbidity of breast carcinoma is often the most relevant with heredity, and 40-60 year between, women's sickness rate before and after menopause higher.The cause of disease of breast carcinoma is the clearest and the most definite, but the factors such as bearing status, oral contraceptive, inherited genetic factors, ionizing radiation, unsound dietary habit have been identified with breast cancer related.The factors such as the most long-term dietary structure, living habit cause body constitution to be excessively acidified, the function decline that human body is overall, cause liver of suffering from a deficiency of the kidney the most empty, and then cause part of the body cavity above the diaphragm housing the heart and lungs metabolic cycles slack-off, easily cause thyroid disease and endocrine disturbance, immunologic function degression, thus develop into mammary gland tissue paraplasm, whole carcinogenesis.Primary disease, in tcm clinical practice, belongs to the category such as " breast carcinoma ", " mammary calculus carbuncle " more, it is believed that breast carcinoma is due to disorder of emotion, depression of liver-QI or because of Chong and Ren channel disorder, QI-blood circulation is smooth, qi stagnation hemagglutination, and meridians block, tie stagnant in caused by Ruzhong.
Current Therapeutic Method mainly has the Drug therapy of operative treatment, radiotherapy and auxiliary, but therapeutic effect is the most undesirable, cures the symptoms, not the disease, and also can recur after healing, and big to patient body wound, easily causes complication, and medical expense is expensive.
Summary of the invention
In order to solve the above-mentioned problems in the prior art, the invention provides a kind of Chinese medicine composition treating breast carcinoma, this traditional Chinese medicine composition for treating is effective, have no side effect, and can cure breast carcinoma.
It is an object of the present invention to provide a kind of Chinese medicine composition treating breast carcinoma, the Chinese medicine of following weight portion be prepared from: Cortex Phellodendri l0-30 part, Herba Cistanches l5-25 part, Spica Prunellae 5-15 part, Caulis Akebiae l0-30 part, Scolopendra 5-15 part, Squama Manis 5-15 part, Radix Angelicae Sinensis 15-30 part, Rhizoma Chuanxiong l0-20 part, Fructus Corni l0-20 part.
In a preferred embodiment, described Chinese medicine composition is preferably prepared from by the Chinese medicine of following weight portion: Cortex Phellodendri 20 parts, Herba Cistanches 25 parts, Spica Prunellae 10 parts, Caulis Akebiae l5 part, Scolopendra 10 parts, Squama Manis 10 parts, Radix Angelicae Sinensis 25 parts, Rhizoma Chuanxiong l5 part, Fructus Corni l5 part.
It is a further object to provide the preparation method of described Chinese medicine composition, specifically comprise the following steps that
1) weigh each crude drug according to compositions proportioning to pulverize, mixing for standby use；
2) by step 1) in crude drug be soaked in water 30-45 minute after, intense fire boils, slow fire boiling 25-35 minute, cool down, filter after obtain filtrate and medicinal residues；
3) by step 2) in obtained by medicinal residues boiling, amount of water was not to have medicinal residues face 2-5cm, and intense fire boils, slow fire boiling 20-30 minute, cool down, filter after obtain filtrate and filtering residue,
4) merge twice filtrate and i.e. obtain the Chinese medicine composition of described treatment breast carcinoma.
In a preferred embodiment, by adding appropriate adjuvant, the present composition can be made suitable pharmaceutical preparation according to the preparation method of this area routine.
State pharmaceutical preparation and be preferably injection and oral formulations.
Described oral formulations is preferably the preparations such as granule, tablet, capsule, soft extract, pill, medicinal tea, powder, drop pill.
Described adjuvant includes the conventional adjuvant that various medical standards is general.
It is also another object of the present invention to provide described Chinese medicine composition medical usage in terms for the treatment of breast carcinoma.In said composition, each medicine synergism, has the effects such as depressed liver-energy dispersing and QI regulating, blood circulation promoting and dispersing pathogen accumulation, anti-inflammatory analgetic, has obvious therapeutical effect to breast carcinoma, and its effective percentage is up to 95%, and cure rate is up to 75%, and controls difficulty in relapse after healing.It is raw material owing to selecting natural plant, to human non-toxic's side effect and cheap, taking convenience.
Detailed description of the invention
Technical scheme is further described by implementation below.It is pointed out that following description is only the illustration to claimed technical scheme, the not any restriction to these technical schemes.The content that protection scope of the present invention is recorded with appended claims is as the criterion.
Embodiment
1
Prescription forms: Cortex Phellodendri 20g, Herba Cistanches 25g, Spica Prunellae 10g, Caulis Akebiae l5g, Scolopendra 10g, Squama Manis 10g, Radix Angelicae Sinensis 25g, Rhizoma Chuanxiong l5g, Fructus Corni l5g；
Preparation method:
1) weigh each crude drug according to prescription composition and ratio to pulverize, mixing for standby use；
2) by step 1) in crude drug be soaked in water 45 minutes after, intense fire boils, slow fire boiling 35 minutes, cool down, filter after obtain filtrate and medicinal residues；
3) by step 2) in obtained by medicinal residues boiling, amount of water was not to have medicinal residues face 3cm, and intense fire boils, slow fire boiling 30 minutes, cool down, filter after obtain filtrate and filtering residue,
4) merge twice filtrate and i.e. obtain the Chinese medicine composition of described treatment breast carcinoma.
Embodiment
2
Prescription forms: Cortex Phellodendri 10g, Herba Cistanches 25g, Spica Prunellae 5g, Caulis Akebiae 25g, Scolopendra 8g, Squama Manis 15g, Radix Angelicae Sinensis 15g, Rhizoma Chuanxiong 20g, Fructus Corni l0g；
Preparation method:
1) weigh each crude drug according to prescription composition and ratio to pulverize, mixing for standby use；
2) by step 1) in crude drug be soaked in water 30 minutes after, intense fire boils, slow fire boiling 30 minutes, cool down, filter after obtain filtrate and medicinal residues；
3) by step 2) in obtained by medicinal residues boiling, amount of water was not to have medicinal residues face 5cm, and intense fire boils, slow fire boiling 20 minutes, cool down, filter after obtain filtrate and filtering residue,
4) merge twice filtrate and i.e. obtain the Chinese medicine composition of described treatment breast carcinoma.
Embodiment
3
Prescription forms: Cortex Phellodendri 30g, Herba Cistanches 15g, Spica Prunellae 15g, Caulis Akebiae 10g, Scolopendra 15g, Squama Manis 5g, Radix Angelicae Sinensis 30g, Rhizoma Chuanxiong 10g, Fructus Corni 20g；
Preparation method:
1) weigh each crude drug according to prescription composition and ratio to pulverize, mixing for standby use；
2) by step 1) in crude drug be soaked in water 40 minutes after, intense fire boils, slow fire boiling 20 minutes, cool down, filter after obtain filtrate and medicinal residues；
3) by step 2) in obtained by medicinal residues boiling, amount of water was not to have medicinal residues face 5cm, and intense fire boils, slow fire boiling 25 minutes, cool down, filter after obtain filtrate and filtering residue,
4) merge twice filtrate and i.e. obtain the Chinese medicine composition of described treatment breast carcinoma.
Embodiment
4
The Clinical observation of Chinese medicine composition of the present invention
1. case selection:
Select to have inpatient's totally 100 example of complete data, the age be 32-58 year, 45 years old mean age.
2. diagnostic criteria:
Touching lump, matter in breast firmly, air spots, pathology or cytolgical examination have found cancerous cell, be diagnosed as breast carcinoma.
3. Therapeutic Method:
Taking the Chinese medicine composition of the embodiment of the present invention 1, potion, sooner or later took at twice, took continuously two months every day.
4.
Efficacy assessment standard:
Disappear (CR) the most entirely: all cancer seen of looking into are wholly absent, and osteolytic lesion is complete on x-ray
Portion's calcification；
2. partial disappearance (PR): pathological changes can be measured and reduce 50%
(products of 2 maximum perpendicular diameters of axle),
Occur without new focus simultaneously；
3. stable without becoming (S): tumor regression <
50%, or increase < 25%.
4. deteriorate (PD): some focus reduces<50%, simultaneously some focus increase>25%, or all focuses increase, or have new focus to occur.
5. therapeutic outcome: (CR) group that entirely disappears in 100 cases is 75 people, and partial disappearance (PR) group is 15 people, stable is 5 people without becoming (S) group, and deteriorating (PD) group is 5 people.Total effective rate is 95%, and cure rate is 75%.
Embodiment
5
Exemplary embodiments
Cai, female, 49 years old, health check-up the year before found lump in breast, and without obvious pain, also aperiodicity change, quality is hard such as rock, and mobility is poor.Being breast carcinoma through hospital diagnosis, disease is seen through thing disorderly, and premenstrual distending pain of the breast, lump in breast is hard, pale tongue, white and thin fur, stringy and thready pulse.Taking after the Chinese medicine composition of the embodiment of the present invention 11 month, the premenstrual distending pain of the breast of patient has alleviated.1 course for the treatment of of the Chinese medicine composition of the following the service embodiment of the present invention 1, the premenstrual distending pain of the breast of patient disappears, and menstrual cycle is normal, and lump in breast reduces earlier above.1 course for the treatment of of the Chinese medicine composition of the following the service embodiment of the present invention 1, lump in breast disappears, and all diseases are all removed, and examination in hospital is without difference.So far do not recur.
China certain, female, 53 years old, the existing lump about 2 × 3.3cm of right suppurative mastitis, matter was hard, rough, the most irregular, and hospital diagnosis is breast carcinoma.Disease sees right arm pain, random thoughts numbness, shallow complexion, tired mind, thin and greasy fur.Taking the Chinese medicine composition 1 month of the embodiment of the present invention 1, patient sleeps improves, and all diseases all have alleviation.Following the service Chinese medicine composition of the present invention 2 months, patient's right breast mass reduction, right arm distending pain, pain and numbness disappear.Following the service Chinese medicine composition of the present invention 1 month, after treatment, the index of tumor is the most normal.Following up a case by regular visits to 1 year, health is good.
Liu, female, 51 years old, confirm suffer from breast carcinoma the most on inspection, breast has lump, pain, weak with health, inappetence, the symptom such as poor sleeping quality, take the Chinese medicine composition of the embodiment of the present invention 1, after 1 month, appetite takes a turn for the better, sleep improvement, and various symptoms have been alleviated.Continuing to take 2 months, lump in breast diminishes, pain relief.Continuing to take 1 month, mammary swelling transference cure, health is strong, finds that through examination in hospital the index of tumor is the most normal.Follow up a case by regular visits to after 1 year without recurrence.
As can be seen here, the Chinese medicine composition of the treatment breast carcinoma of the present invention is evident in efficacy, with low cost, has broad application prospects.
Present invention merely illustrates some claimed specific embodiments; technical characteristic described in one of them or more technical scheme can be combined with arbitrary one or more technical schemes; the technical scheme that these are combined and obtain is also in the application protection domain, technical scheme that is combined just as these and that obtain specifically is recorded in the disclosure of invention.
Claims (1)
1. the Chinese medicine composition treating breast carcinoma, it is characterised in that it is by the Chinese medicine preparation of following weight
Become: Cortex Phellodendri 20g, Herba Cistanches 25g, Spica Prunellae 10g, Caulis Akebiae l5g, Scolopendra 10g, Squama Manis 10g, Radix Angelicae Sinensis 25g, Rhizoma Chuanxiong l5g, Fructus Corni l5g；
Wherein, the preparation method of described Chinese medicine composition is:
1) weigh each crude drug according to prescription composition and ratio to pulverize, mixing for standby use；
2) by step 1) in crude drug be soaked in water 45 minutes after, intense fire boils, slow fire boiling 35 minutes, cool down, filter after obtain filtrate and medicinal residues；
3) by step 2) in obtained by medicinal residues boiling, amount of water was not to have medicinal residues face 3cm, and intense fire boils, slow fire boiling 30 minutes, cool down, filter after obtain filtrate and filtering residue,
4) merge twice filtrate and i.e. obtain the Chinese medicine composition of described treatment breast carcinoma.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410070739.XA CN103800505B (en) | 2014-02-28 | A kind of Chinese medicine composition treating breast carcinoma and its preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410070739.XA CN103800505B (en) | 2014-02-28 | A kind of Chinese medicine composition treating breast carcinoma and its preparation method and application |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103800505A CN103800505A (en) | 2014-05-21 |
| CN103800505B true CN103800505B (en) | 2016-11-30 |
Family
ID=
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6004558A (en) * | 1998-02-25 | 1999-12-21 | Novogen, Inc. | Methods for treating cancer with legume plant extracts |
| CN1490029A (en) * | 2003-05-27 | 2004-04-21 | 波 张 | Ruxiankang tablets for mammary gland |
| CN103550695A (en) * | 2013-11-01 | 2014-02-05 | 田静 | Medicament for treating breast cancer |
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6004558A (en) * | 1998-02-25 | 1999-12-21 | Novogen, Inc. | Methods for treating cancer with legume plant extracts |
| CN1490029A (en) * | 2003-05-27 | 2004-04-21 | 波 张 | Ruxiankang tablets for mammary gland |
| CN103550695A (en) * | 2013-11-01 | 2014-02-05 | 田静 | Medicament for treating breast cancer |
Non-Patent Citations (2)
| Title |
|---|
| 乳腺癌的中医治疗;张勇;《光明中医》;20090131;第24卷(第1期);第178-181页 * |
| 女性乳腺癌的阳虚症候特点研究;刘学武;《中国优秀硕士论文医药卫生特辑》;20091231(第1期);第E056-331页 * |
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| CB03 | Change of inventor or designer information |
Inventor after: Xu Yan Inventor after: Liu Wu Inventor after: Chen Qian Inventor after: Li Chunyan Inventor before: Zhang Zhen Inventor before: Zhang Xiaotao Inventor before: Han Shuyan Inventor before: Han Shuhong |
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| TA01 | Transfer of patent application right |
Effective date of registration: 20160928 Address after: Qingdao City, Shandong province 266000 four Road No. 127 Applicant after: QINGDAO TUMOUR HOSPITAL Address before: 266071 Shandong Province, Qingdao city Jinhu Road No. 30 2-1-604 Applicant before: Zhang Zhen Applicant before: Han Shuhong |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20161130 Termination date: 20170228 |