CN103495121A - Mammary gland externally-applied medicament bag and manufacturing method thereof - Google Patents
Mammary gland externally-applied medicament bag and manufacturing method thereof Download PDFInfo
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Abstract
The invention discloses a mammary gland externally-applied medicament bag and a manufacturing method thereof. The mammary gland externally-applied medicament bag consists of the following components in parts by weight: 1.0 to 30 g of folium artemisiae argyi, 1.0 to 30 g of cassia twig, 1.0 to 30 g of galangal, 1.0 to 30 g of agastache rugosus, 1.0 to 30 g of dalbergia wood, 1.0 to 30 g of rhizoma cyperi, 1.0 to 30 g of radix angelicae dahuricae, 1.0 to 30 g of tangerine peel, 1.0 to 30 g of salviae miltiorrhizae, 1.0 to 30 g of crude sichuan aconite root, 1.0 to 30 g of ligusticum wallichii, 1.0 to 30 g of radix curcumae, 1.0 to 30 g of cowherb seed and 1.0 to 30 g of moneywort. The mammary gland externally-applied medicament bag disclosed by the invention is a product blended and processed by leaves, flowers, fruits, roots and the like of natural medicinal plants in certain ratio, and is packaged by a high-permeability and pro-cutaneous cloth bag. The mammary gland external-application medicament bag disclosed by the invention consists of fourteen medicaments, and the components are cooperated with one another, so that the overall medicament bag has the effects of warming and activating meridian, promoting the circulation of Qi, dispersing blood stasis, eliminating mass, removing stasis and the like, and has an obvious treatment effect on mammary gland hyperplasia diseases.
Description
Technical field
The present invention relates to a kind of outer charging, specifically, relate to a kind of mammary gland outer charging and preparation method thereof.
Background technology
Cyclomastopathy is the modal cystic hyperplasia of breast of women, and its sickness rate accounts for the first place of mastopathy.This disease sickness rate was the trend risen year by year in the last few years, and the age also more and more becomes younger.In adolescence or young women, premenstrual have distending pain of the breast, sometimes pain can involve the shoulder back, through the spontaneous remission gradually of rear udder attachment pain, only can contact mammary gland and a bit thicken, without obvious tuberosity, these are that physiological changes, not disease, do not need treatment yet, belong to physiological hypertrophy.Cyclomastopathy is normal breast lobule physiological hypertrophy and subinvolution, and the mammary gland normal configuration gets muddled, and belongs to pathological proliferation, and it is neither an inflammation class disease of non-tumor again.Be mainly in 30-50 year women, onset peak is 35-40 year.
Because mechanism and the cause of disease that cyclomastopathy is occurred there is no definite understanding, treatment at present is upper is symptomatic treatment substantially.But part patient falls ill, how rear several months to 1～2 year normal afterwards spontaneous remission, do not need treatment.Cyclomastopathy has a lot of types, and physiological cyclomastopathy, as Simple proliferation of mammary gland, does not need special handling, can disappear voluntarily.Because the cyclomastopathy that spirit, emotion and anthropic factor cause, by adjustment (other organ disease as relevant to the mastopathy generation as timely diagnosis and treatment of self, regulate emotion, alleviate stress, change unsound dietary habit, discontinue the habit of smoking and drinking etc.) also can disappear or alleviate.
Pathologic cyclomastopathy, need active treatment, and especially the cystic hyperplasia type, due to the possibility that has canceration, can not adopt a casual attitude.Medicine majority commonly used is Chinese patent medicine clinically, has the effects such as blood circulation promoting and blood stasis dispelling, depressed liver-energy dispersing and QI regulating, hard masses softening and resolving, compensate qi and blood.In addition, hormonotherapy is still arranged, someone adopts the androgen in treating primary disease, but that this treatment likely aggravates between the human hormone is unbalance, unsuitable conventional application.Only, at serious symptom, when impact normal operation and life, just consider to adopt.Under doctor's guidance, treat: Western medicine has 5% potassium iodide, and the pain severe patient can be tried out methyl testosterone or tamoxifen, within menstruation the last week, start oral, in order to avoid further upset the trickle balance between the human hormone.Also can under instructing, select Chinese medical discrimination Chinese patent medicine or prescription treatment.
Summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art, significant mammary gland outer charging of a kind of therapeutic effect and preparation method thereof is provided.
To achieve these goals, the present invention adopts following technical scheme:
A kind of mammary gland outer charging is comprised of the component of following parts by weight:
Folium Artemisiae Argyi 1.0-30g, Ramulus Cinnamomi 1.0-30g, Rhizoma Alpiniae Officinarum 1.0-30g, Herba Pogostemonis 1.0-30g, Lignum Dalbergiae Odoriferae 1.0-30g, Rhizoma Cyperi 1.0-30g, Radix Angelicae Dahuricae 1.0-30g, Pericarpium Citri Reticulatae 1.0-30g, Radix Salviae Miltiorrhizae 1.0-30g, Radix Aconiti 1.0-30g, Rhizoma Chuanxiong 1.0-30g, Radix Curcumae 1.0-30g, Semen Vaccariae 1.0-30g, Radix seu Folium Gaultheriae Forrestii 1.0-30g.
In side, Folium Artemisiae Argyi has warming the meridian for stopping bleeding, cold expelling regulating menstruation, the effect such as antiabortive; In side, Ramulus Cinnamomi has the diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, the effects such as dispersing cold for relieving pain; In side, Rhizoma Alpiniae Officinarum has warming stomach for dispelling cold, and the effects such as pain relieving help digestion; In side, Herba Pogostemonis has eliminating turbid pathogen with aromatics, and the appetizing preventing or arresting vomiting, deliver the effects such as expelling summer-heat; In side, Lignum Dalbergiae Odoriferae has promoting flow of QI and blood, pain relieving, the effects such as hemostasis; In side, Rhizoma Cyperi has the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving, the effect such as antiabortive; In side, the Radix Angelicae Dahuricae has expelling wind and cold, understand things pain-stopping, the evacuation of pus of invigorating blood circulation, granulation promoting pain relieving, the effects such as dampness leukorrhagia stopping; In side, Pericarpium Citri Reticulatae has regulating qi-flowing for strengthening spleen, the effects such as drying dampness to eliminate phlegm; In side, Radix Salviae Miltiorrhizae has promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness effect such as calm the nerves; In side, Radix Aconiti has expelling wind and removing dampness, the effects such as antalgic; In side, Rhizoma Chuanxiong has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effects such as wind-expelling pain-stopping; In side, Radix Curcumae has promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, and the effects such as removing heat from blood, promoting the function of the gallbladder to alleviate jaundice clear away heart-fire; In side, Semen Vaccariae has the promoting the circulation of blood regulating menstruation, reducing swelling and alleviating pain, and the lactogenesis of invigorating blood circulation, expedite the emergence of stimulating milk secretion, the effects such as thymus dredging in puerperal; In side, Radix seu Folium Gaultheriae Forrestii has heat-clearing and toxic substances removing, the eliminating carbuncle of invigorating blood circulation, expelling wind and removing dampness sore, the effects such as snake bite and insect sting.
This ten four Chinese medicine coordinates the effect with obvious control hyperplasia of mammary glands in limited ratio.
The manufacture method of above-mentioned mammary gland outer charging, comprise the steps: each component is picked, smashes or grinding, drying process through choosing, and then dry each component required to carry out weight ratio according to formula assorted, and take breathability, close skin cloth bag packing; The dust proof workshop that the production environment requirement is 100,000 grades.
The using method of above-mentioned mammary gland outer charging comprises: the bag of getting it filled before use is put into family's microwave oven, with in high fire heat after 1-2 minute and can use.
Compared with prior art, the present invention has following beneficial effect: mammary gland outer charging of the present invention is that to take the leaf, flower, fruit, rhizome etc. of pure natural medicinal plants be raw material, the assorted product be processed into by a certain percentage, and by highly-breathable, close skin cloth bag packing.Outer charging of the present invention consists of in proportion ten four Chinese medicines, and each component synergism makes whole medicated bag have the effects such as promoting the flow of QI in the collateral by warming the meridian, regulating qi to disperse stagnation, Xiao Disorder eliminating stagnation, and hyperplasia of mammary glands is had to obvious therapeutical effect.
This employing pure natural of the present invention medicinal plants is as the mammary gland outer charging of effective ingredient, the health care theory and the living habit that more meet modern female, have simultaneously the use of being simple and easy to, non-evident effect, can repeated multiple times use characteristics, the hyperplasia of mammary glands that is used for the treatment of the women, have more wide market prospect.In addition, the preparation technology of mammary gland outer charging of the present invention is simple, easy to operate, repeatability is good, is suitable for suitability for industrialized production.
The specific embodiment
Embodiment 1
Formula: Folium Artemisiae Argyi 1g, Ramulus Cinnamomi 5g, Rhizoma Alpiniae Officinarum 25g, Herba Pogostemonis 30g, Lignum Dalbergiae Odoriferae 8g, Rhizoma Cyperi 21g, Radix Angelicae Dahuricae 27g, Pericarpium Citri Reticulatae 7g, Radix Salviae Miltiorrhizae 12g, Radix Aconiti 15g, Rhizoma Chuanxiong 18g, Radix Curcumae 30g, Semen Vaccariae 30g, Radix seu Folium Gaultheriae Forrestii 9g.
Manufacture method: (1) takes Folium Artemisiae Argyi, Ramulus Cinnamomi, Rhizoma Alpiniae Officinarum, Herba Pogostemonis, Lignum Dalbergiae Odoriferae, Rhizoma Cyperi, the Radix Angelicae Dahuricae, Pericarpium Citri Reticulatae, Radix Salviae Miltiorrhizae, Radix Aconiti, Rhizoma Chuanxiong, Radix Curcumae, Semen Vaccariae and Radix seu Folium Gaultheriae Forrestii by weight.(2) according to formulation ratio, pack in the cloth bag of highly-breathable, the making of close skin cloth.The bag of getting it filled before use is put into family's microwave oven, with in high fire heat after 1-2 minute and can use.
Embodiment 2
Formula: Folium Artemisiae Argyi 30g, Ramulus Cinnamomi 22g, Rhizoma Alpiniae Officinarum 7g, Herba Pogostemonis 9g, Lignum Dalbergiae Odoriferae 12g, Rhizoma Cyperi 19g, Radix Angelicae Dahuricae 30g, Pericarpium Citri Reticulatae 30g, Radix Salviae Miltiorrhizae 23g, Radix Aconiti 2g, Rhizoma Chuanxiong 5g, Radix Curcumae 9g, Semen Vaccariae 15g, Radix seu Folium Gaultheriae Forrestii 25g.
Manufacture method: (1) takes Folium Artemisiae Argyi, Ramulus Cinnamomi, Rhizoma Alpiniae Officinarum, Herba Pogostemonis, Lignum Dalbergiae Odoriferae, Rhizoma Cyperi, the Radix Angelicae Dahuricae, Pericarpium Citri Reticulatae, Radix Salviae Miltiorrhizae, Radix Aconiti, Rhizoma Chuanxiong, Radix Curcumae, Semen Vaccariae and Radix seu Folium Gaultheriae Forrestii by weight.(2) according to formulation ratio, pack in the cloth bag of highly-breathable, the making of close skin cloth.The bag of getting it filled before use is put into family's microwave oven, with in high fire heat after 1-2 minute and can use.
Embodiment 3
Formula: Folium Artemisiae Argyi 15g, Ramulus Cinnamomi 15g, Rhizoma Alpiniae Officinarum 9g, Herba Pogostemonis 21g, Lignum Dalbergiae Odoriferae 24g, Rhizoma Cyperi 1g, Radix Angelicae Dahuricae 20g, Pericarpium Citri Reticulatae 10g, Radix Salviae Miltiorrhizae 3g, Radix Aconiti 21g, Rhizoma Chuanxiong 15g, Radix Curcumae 19g, Semen Vaccariae 5g, Radix seu Folium Gaultheriae Forrestii 5g.
Manufacture method: (1) takes Folium Artemisiae Argyi, Ramulus Cinnamomi, Rhizoma Alpiniae Officinarum, Herba Pogostemonis, Lignum Dalbergiae Odoriferae, Rhizoma Cyperi, the Radix Angelicae Dahuricae, Pericarpium Citri Reticulatae, Radix Salviae Miltiorrhizae, Radix Aconiti, Rhizoma Chuanxiong, Radix Curcumae, Semen Vaccariae and Radix seu Folium Gaultheriae Forrestii by weight.(2) according to formulation ratio, pack in the cloth bag of highly-breathable, the making of close skin cloth.The bag of getting it filled before use is put into family's microwave oven, with in high fire heat after 1-2 minute and can use.
Embodiment 4
Formula: Folium Artemisiae Argyi 5g, Ramulus Cinnamomi 25g, Rhizoma Alpiniae Officinarum 19g, Herba Pogostemonis 12g, Lignum Dalbergiae Odoriferae 3g, Rhizoma Cyperi 12g, Radix Angelicae Dahuricae 25g, Pericarpium Citri Reticulatae 20g, Radix Salviae Miltiorrhizae 30g, Radix Aconiti 8g, Rhizoma Chuanxiong 7g, Radix Curcumae 23g, Semen Vaccariae 25g, Radix seu Folium Gaultheriae Forrestii 1g.
Manufacture method: (1) takes Folium Artemisiae Argyi, Ramulus Cinnamomi, Rhizoma Alpiniae Officinarum, Herba Pogostemonis, Lignum Dalbergiae Odoriferae, Rhizoma Cyperi, the Radix Angelicae Dahuricae, Pericarpium Citri Reticulatae, Radix Salviae Miltiorrhizae, Radix Aconiti, Rhizoma Chuanxiong, Radix Curcumae, Semen Vaccariae and Radix seu Folium Gaultheriae Forrestii by weight.(2) according to formulation ratio, pack in the cloth bag of highly-breathable, the making of close skin cloth.The bag of getting it filled before use is put into family's microwave oven, with in high fire heat after 1-2 minute and can use.
Embodiment 5
Formula: Folium Artemisiae Argyi 25g, Ramulus Cinnamomi 5g, Rhizoma Alpiniae Officinarum 1g, Herba Pogostemonis 22g, Lignum Dalbergiae Odoriferae 30g, Rhizoma Cyperi 2g, Radix Angelicae Dahuricae 15g, Pericarpium Citri Reticulatae 10g, Radix Salviae Miltiorrhizae 10g, Radix Aconiti 18g, Rhizoma Chuanxiong 17g, Radix Curcumae 13g, Semen Vaccariae 15g, Radix seu Folium Gaultheriae Forrestii 11g.
Manufacture method: (1) takes Folium Artemisiae Argyi, Ramulus Cinnamomi, Rhizoma Alpiniae Officinarum, Herba Pogostemonis, Lignum Dalbergiae Odoriferae, Rhizoma Cyperi, the Radix Angelicae Dahuricae, Pericarpium Citri Reticulatae, Radix Salviae Miltiorrhizae, Radix Aconiti, Rhizoma Chuanxiong, Radix Curcumae, Semen Vaccariae and Radix seu Folium Gaultheriae Forrestii by weight.(2) according to formulation ratio, pack in the cloth bag of highly-breathable, the making of close skin cloth.The bag of getting it filled before use is put into family's microwave oven, with in high fire heat after 1-2 minute and can use.
Embodiment 6 efficacy experiments
1. data and method
1.1 case is selected:
Cyclomastopathy female patient 150 examples of 25～45 years old of outpatient clinic.Every equal detailed medical history-taking of patient and complete every physical examination, through mammary X-ray+ultrasonic examination, diagnosis meets WHO standard.Except following situation: liver or renal function serious hindrance, serious habits of smoking and alcohol drinking, anemia of pregnant woman, women breast-feeding their children, malignant tumor medical history, psychosis medical history etc.
1.2 test method: all stop using other treatment before 150 patient more than 5 days, 3 days begin treatments after menstruation.Treatment measure: be divided at random 6 groups of each 25 people.(1) 1-5 group is mammary gland application compress package: mammary gland outer charging external application symptom side mammary gland, every day 3 times, each 20 minutes, 2 totally months course for the treatment of, the 1-5 group was distinguished the medicated bag of corresponding embodiment 1-5 successively.(2) the 6th groups is the hot-water bag group: hot-water bag external application symptom side mammary gland, every day 3 times, each 20 minutes, 2 totally months course for the treatment of.
1.3 observation index and method: respectively followed up a case by regular visits to 1 time February after latter 1 week for the treatment of, latter 2 weeks for the treatment of, menstruation the 1st day, last 1 day of menstruation, treatment by Permanent doctor, follow up a case by regular visits to altogether 5 times.Follow up a case by regular visits at every turn and all inquire in detail and symptom complete every physical examination, and carry out the VAS pain scores.The VAS pain scores: be the visual analogue scales directly perceived of pain, this scoring can reflect patient's subjective pain degree more objectively, and the scoring scope is 0～10 minute, and mark is higher, means that patient's pain degree is higher.
1.4 date processing and statistical method: between group and before and after the group internal therapy, relatively with t, check, effective percentage is relatively used X 2 test.
2. result
2.1 efficacy analysis
2.1.1 before and after treatment, pain scores changes: before the mammary gland application compress package treatment of (1) embodiment 1, average out to is 5.71 ± 1.56 minutes, after treatment, 1 week average out to is 3.36 ± 1.42 minutes, after treatment, 2 weeks average out to are 2.12 ± 1.01 minutes, the 1st day average out to of menstruation 2.66 ± 2.20 minutes, last 1 day average out to of menstruation 2.54 ± 1.14 minutes, after treatment, 2 monthly average are 1.81 ± 1.63 minutes.
Before the mammary gland application compress package treatment of embodiment 2, average out to is 5.62 ± 1.55 minutes, after treatment, 1 week average out to is 3.41 ± 1.71 minutes, after treatment, 2 weeks average out to are 2.08 ± 1.22 minutes, the 1st day average out to of menstruation 2.59 ± 2.11 minutes, last 1 day average out to of menstruation 2.49 ± 1.04 minutes, after treatment, 2 monthly average are 1.77 ± 1.25 minutes.
Before the mammary gland application compress package treatment of embodiment 3, average out to is 5.44 ± 1.12 minutes, after treatment, 1 week average out to is 3.75 ± 1.35 minutes, after treatment, 2 weeks average out to are 2.22 ± 1.35 minutes, the 1st day average out to of menstruation 2.78 ± 2.02 minutes, last 1 day average out to of menstruation 2.48 ± 1.11 minutes, after treatment, 2 monthly average are 1.74 ± 1.35 minutes.
Before the mammary gland application compress package treatment of embodiment 4, average out to is 5.77 ± 1.29 minutes, after treatment, 1 week average out to is 3.52 ± 1.24 minutes, after treatment, 2 weeks average out to are 2.51 ± 1.08 minutes, the 1st day average out to of menstruation 2.43 ± 2.08 minutes, last 1 day average out to of menstruation 2.47 ± 1.27 minutes, after treatment, 2 monthly average are 1.90 ± 1.38 minutes.
Before the mammary gland application compress package treatment of embodiment 5, average out to is 5.80 ± 1.42 minutes, after treatment, 1 week average out to is 3.47 ± 1.34 minutes, after treatment, 2 weeks average out to are 2.18 ± 1.30 minutes, the 1st day average out to of menstruation 2.57 ± 2.42 minutes, last 1 day average out to of menstruation 2.24 ± 1.00 minutes, after treatment, 2 monthly average are 1.59 ± 1.54 minutes.
After treatment, each time followed up a case by regular visits to scoring all lower than before treatment, and difference all has remarkable statistical significance (P<0.01).
(2) the front average out to of hot-water bag group treatment is 5.69 ± 2.13 minutes, after treatment, 1 week average out to is 5.21 ± 2.74 minutes, after treatment, 2 weeks average out to are 4.49 ± 2.35 minutes, the 1st day average out to of menstruation 6.45 ± 2.27 minutes, last 1 day average out to of menstruation 6.38 ± 1.79 minutes, after treatment, 2 monthly average are 3.95 ± 1.61 minutes.After treating latter 2 weeks and treating, front reduction is all treated in the scoring in February, and difference has remarkable statistical significance (P<0.05); Menstruation the 1st day and menstruation scoring in last 1 day all raises before treatment, and difference has remarkable statistical significance (P<0.05).
2.1.2 respectively following up a case by regular visits to scoring between the time point group compares: before treatment, two groups of scorings are without significant difference.After treatment, respectively follow up a case by regular visits to a little, the scoring of mammary gland application compress package is all low than the hot-water bag group, and difference all has remarkable statistical significance (P<0.01).
2.2 untoward reaction: without the patient, the untoward reaction symptom occurs.
3. conclusion
The mammary gland application compress package of embodiment 1-5 can obviously improve cyclomastopathy patient pain symptom, especially can control the pain outbreak of patient at intermenstrual period, evident in efficacy, and, without bad side effect, is simple and easy to use, is adapted at family and clinical expansion and uses.
Claims (3)
1. a mammary gland outer charging, is characterized in that, the component of following parts by weight, consists of:
Folium Artemisiae Argyi 1.0-30g, Ramulus Cinnamomi 1.0-30g, Rhizoma Alpiniae Officinarum 1.0-30g, Herba Pogostemonis 1.0-30g, Lignum Dalbergiae Odoriferae 1.0-30g, Rhizoma Cyperi 1.0-30g, Radix Angelicae Dahuricae 1.0-30g, Pericarpium Citri Reticulatae 1.0-30g, Radix Salviae Miltiorrhizae 1.0-30g, Radix Aconiti 1.0-30g, Rhizoma Chuanxiong 1.0-30g, Radix Curcumae 1.0-30g, Semen Vaccariae 1.0-30g, Radix seu Folium Gaultheriae Forrestii 1.0-30g.
2. the manufacture method of the described mammary gland outer charging of claim 1, it is characterized in that comprising the steps: each component is picked, smashes or grinding, drying process through choosing, then dry each component is required to carry out weight ratio according to filling a prescription assorted, and take breathability, close skin cloth bag packing; The dust proof workshop that the production environment requirement is 100,000 grades.
3. the using method of the described mammary gland outer charging of claim 1, is characterized in that, the bag of getting it filled before use is put into family's microwave oven, with in high fire heat after 1-2 minute and can use.
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Application publication date: 20140108 |