CN106309749A - Traditional Chinese medicine for treating cervical cancer - Google Patents
Traditional Chinese medicine for treating cervical cancer Download PDFInfo
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- CN106309749A CN106309749A CN201610889602.6A CN201610889602A CN106309749A CN 106309749 A CN106309749 A CN 106309749A CN 201610889602 A CN201610889602 A CN 201610889602A CN 106309749 A CN106309749 A CN 106309749A
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- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 title claims abstract description 27
- 201000010881 cervical cancer Diseases 0.000 title claims abstract description 27
- 206010008342 Cervix carcinoma Diseases 0.000 title claims abstract description 26
- 239000003814 drug Substances 0.000 title claims abstract description 19
- 239000009526 Fructus Akebiae Substances 0.000 claims abstract description 6
- 239000000706 filtrate Substances 0.000 claims description 6
- 241000628997 Flos Species 0.000 claims description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- 229940079593 drug Drugs 0.000 claims description 2
- 239000000284 extract Substances 0.000 claims description 2
- 238000010438 heat treatment Methods 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 241000271039 Agkistrodon Species 0.000 claims 1
- 238000011282 treatment Methods 0.000 abstract description 23
- 206010028980 Neoplasm Diseases 0.000 abstract description 12
- 201000011510 cancer Diseases 0.000 abstract description 10
- 244000307697 Agrimonia eupatoria Species 0.000 abstract 1
- 240000000011 Artemisia annua Species 0.000 abstract 1
- 235000001405 Artemisia annua Nutrition 0.000 abstract 1
- 240000005250 Chrysanthemum indicum Species 0.000 abstract 1
- 235000018959 Chrysanthemum indicum Nutrition 0.000 abstract 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 abstract 1
- 241000717675 Clerodendranthus Species 0.000 abstract 1
- 240000007890 Leonurus cardiaca Species 0.000 abstract 1
- 235000000802 Leonurus cardiaca ssp. villosus Nutrition 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 240000001659 Oldenlandia diffusa Species 0.000 abstract 1
- 244000148137 Patrinia villosa Species 0.000 abstract 1
- 235000019109 Patrinia villosa Nutrition 0.000 abstract 1
- 240000004274 Sarcandra glabra Species 0.000 abstract 1
- 235000010842 Sarcandra glabra Nutrition 0.000 abstract 1
- 240000004534 Scutellaria baicalensis Species 0.000 abstract 1
- 235000017089 Scutellaria baicalensis Nutrition 0.000 abstract 1
- 235000000125 common agrimony Nutrition 0.000 abstract 1
- 230000036737 immune function Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000009401 metastasis Effects 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 208000032843 Hemorrhage Diseases 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 3
- 230000000740 bleeding effect Effects 0.000 description 3
- 210000003679 cervix uteri Anatomy 0.000 description 3
- 238000002512 chemotherapy Methods 0.000 description 3
- 238000001959 radiotherapy Methods 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 201000009030 Carcinoma Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 208000019065 cervical carcinoma Diseases 0.000 description 2
- 238000002651 drug therapy Methods 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000005180 public health Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 206010000084 Abdominal pain lower Diseases 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 235000003826 Artemisia Nutrition 0.000 description 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 description 1
- 240000006891 Artemisia vulgaris Species 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 206010027336 Menstruation delayed Diseases 0.000 description 1
- 208000019914 Mental Fatigue Diseases 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010040007 Sense of oppression Diseases 0.000 description 1
- 206010046910 Vaginal haemorrhage Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 208000024776 abnormal vaginal bleeding Diseases 0.000 description 1
- 235000009052 artemisia Nutrition 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000003756 cervix mucus Anatomy 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
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- 230000036039 immunity Effects 0.000 description 1
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- 239000002994 raw material Substances 0.000 description 1
- 208000009146 rhinoscleroma Diseases 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 210000004999 sex organ Anatomy 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/84—Valerianaceae (Valerian family), e.g. valerian
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention discloses a traditional Chinese medicine for treating cervical cancer. The traditional Chinese medicine is prepared from sarcandra glabra, mother chrysanthemum, sweet wormwood, radix sophorae flavescentis, fructus akebiae, spicate clerodendranthus herb, patrinia, hairyvein agrimony, oldenlandia diffusa, motherwort and scutellaria baicalensis. The medicine can achieve the aims of effectively improving the immunologic functions of patients suffering from cervical cancer, improving the constitution, inhibiting and killing cancer cells, softening and reducing tumors and increasing endurance of the patients suffering from cervical cancer; and moreover, reoccurrence and metastasis of the cervical cancer can be prevented, and the opportunity of treatment is increased.
Description
Technical field
The invention mainly relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine treating cervical cancer.
Background technology
Cervical cancer has generation all over the world, is one of modal carcinoma of human body, not only in female sex organ cancer
Tumor accounts for first place, and is carcinoma the most common in the various malignant tumor of women, but its sickness rate has obvious regional difference.I
The generation of state's cervical cancer, the feature in geographical distribution is that district occurred frequently often connects in flakes.Each province's cervical cancer relative to district occurred frequently city,
The most often there is interconnection phenomenon in county.Total trend is that rural area is higher than city, mountain area higher than Plain.According to 29 provinces, municipalities and autonomous regions
Retrospective survey China Mortality of cervix cancer accounts for the 4th of total cancer mortality, accounts for the second of women cancer.Cervical cancer patient
Average age of onset, various countries, various places report are the most variant, and China's age of onset is most with 40～50 years old, and 60～have again for 70 years old
One peak occurs, rare before 20 years old.
The western medical treatment mode of cervical cancer is our known operative treatment, radiotherapy, chemotherapy.Western medical treatment
Although instant effect, but easily recur, side effect is big.So in for, the expectant treatment in late period, or the Radiotherapy chemotherapy after early operation
Auxiliary treatment, the traditional Chinese medical science plays an important role, but the most uncertain therapeutic efficacy of existing Chinese medicine formula is cut.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine treating cervical cancer, all select natural Chinese medicinal herb, it is possible to effectively
Treatment cervical cancer.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine treating cervical cancer, is made up of the crude drug of following parts by weight: Herba Sarcandrae 30 parts, Flos Chrysanthemi Indici 60 parts, green grass or young crops
Artemisia 90 parts, Radix Sophorae Flavescentis 30 parts, Fructus Akebiae 60 parts, Herba clerodendranthi spicati 30 parts, Herba Patriniae 60 parts, Herba Agrimoniae 60 parts, Herba Hedyotidis Diffusae 60 parts, benefit
Herba Linderniae Crustaceae 30 parts, Radix Scutellariae 15 parts.
The invention have the advantage that
Chinese medicine of the present invention has heat-clearing and toxic substances removing, blood stasis-eliminating and stagnation-dissipating, detumescence and promoting granulation, effect of inrigorating qi and promoting blood circulation, and it uses treating both the principal and secondary aspects of a disease
Method, strengthening vital QI to eliminate pathogenic factors, alleviating pain, body immunity, the growth of suppression cancer cell can be strengthened, and it is thin to kill cancer further
Born of the same parents, reach to cure the purpose of cervical cancer.
Detailed description of the invention:
A kind of Chinese medicine treating cervical cancer, the weight (g) of its each raw material components is: Herba Sarcandrae 30, Flos Chrysanthemi Indici 60, Herba Artemisiae Annuae 90, hardship
Ginseng 30, Fructus Akebiae 60, Herba clerodendranthi spicati 30, Herba Patriniae 60, Herba Agrimoniae 60, Herba Hedyotidis Diffusae 60, Herba Leonuri 30, Radix Scutellariae 15.
By proportioning weigh Herba Sarcandrae, Flos Chrysanthemi Indici, Radix Sophorae Flavescentis, Fructus Akebiae, Herba clerodendranthi spicati, Herba Patriniae, Herba Agrimoniae, Herba Hedyotidis Diffusae,
Radix Scutellariae, the 100 DEG C of heating of water adding 10 times amount (V/W) are concentrated into original volume 1/5, and filter to get filtrate A；
Take Herba Artemisiae Annuae, Herba Leonuri in proportion, add 10% EtOH Sonicate (500W, 80kHz) and extract 1h, filter, filtrate is placed in 60 DEG C
After volatilizing solvent, it is mixed in filtrate A and prepares potion.Take at twice, every day potion.
For proving that the present invention has a good curative effect, clinical data and to enumerate model case as follows:
Clinical observation
1, clinical data: selected from outpatient service and inpatient totally 78 example, the wherein early cervical carcinoma in June, 2011 in JIUYUE, 2012
26 examples.Age is 48-64 year, average 56.4 years old.
2, diagnostic criteria: with the diagnosis of cervical cancer mark in " China's common cancer diagnosis and treatment specification " that China's Ministry of Public Health is compiled
Standard is foundation.Clinical stages, all belongs to II phase, III phase, IV phase.Meet standard and the visitor of " China's common cancer diagnosis and treatment specification "
See efficacy assessment standard, use WHO standard to evaluate.
3, Therapeutic Method: take medicine of the present invention, sooner or later take at twice.It within 1 month, it is 1 course for the treatment of.
4, efficacy assessment standard: according to Ministry of Public Health " China's common cancer diagnosis and treatment specification " cervical cancer efficacy evaluation mark
Standard, with before patient treatment with treatment after B super or CT compares, alleviate (PR), stable with complete incidence graph (CR), part
(SD), progress (PD) carries out efficacy evaluation.
5, therapeutic outcome: complete incidence graph 62 example, part is alleviated 7 examples, is stablized 9 examples, is in progress 0 example.Effective percentage (CR+PR) is
88.5%, coefficient of stabilization (CR+PR+SD) is 100%.(tumor all disappears to have 20 examples to cure the most in early days in 26 example early cervical carcinomas
Lose, follow up a case by regular visits to 1 year not recur).
In sum, the present invention, for treating the medicine of cervical cancer, through clinical trial, shows that it can effectively suppress cervical cancer
Development, improves patients symptomatic, sign, and without obvious toxic-side effects.
Case one:
Zhu, man, 49 years old.This patient's hemorrhage of cervix, is diagnosed as cervical cancer in early days through examination in hospital.?
In western medical treatment and chemotherapy process, nausea and vomiting, inappetence, stop treatment.Through taking Drug therapy one of the present invention
After the individual course for the treatment of, there is not bleeding in cervix uteri, and vaginal secretions is normal, after the course for the treatment of of continuing to take medicine, and transference cure, extensive
Multiple normal.
Case two:
Mrs Zhao, 38 years old., there is haemorrhagia sub coitu symptom in patient's lower abdominal pain the most often, and recent leucorrhea is many and has abnormal flavour.Go doctor
It is cervical cancer that institute makes a definite diagnosis on inspection, and after taking two courses for the treatment of of Drug therapy of the present invention, bleeding substantially eliminates, hypogastralgia
Alleviating, leucorrhea is normal, and after two courses for the treatment of of continuing to take medicine, rehabilitation is fully recovered.
Case three:
Solemn so-and-so, female, 48 years old, people from Xi'an.Patient, because of abnormal vaginal bleeding more than a year, has 3 by certain examination in hospital cervix uteri
Individual scleroma, contact bleeding.Being diagnosed as the cervical cancer second phase, after five courses for the treatment of of row radiotherapy, aggravation, vaginal hemorrhage amount is many, weak
Few gas Mental fatigue, lower abdominal distention pain.Taking two courses for the treatment of of treatment by Chinese herbs of the present invention, symptom takes a turn for the better, and sensation of oppression over the chest with shortness of breath alleviates, and lower abdomen pain subtracts
Gently, food of receiving increases, and two is the most normal.Top plus-minus two courses for the treatment of of following the service, symptom disappears substantially.
Claims (2)
1. the Chinese medicine treating cervical cancer, it is characterised in that be made up of the crude drug of following parts by weight: Herba Sarcandrae 30 parts, open country
Flos Chrysanthemi 60 parts, Herba Artemisiae Annuae 90 parts, Radix Sophorae Flavescentis 30 parts, Fructus Akebiae 60 parts, Herba clerodendranthi spicati 30 parts, Herba Patriniae 60 parts, Herba Agrimoniae 60 parts, Agkistrodon
SHECAO 60 parts, Herba Leonuri 30 parts, Radix Scutellariae 15 parts.
A kind of Chinese medicine treating cervical cancer the most according to claim 1, it is characterised in that comprise the following steps:
1) proportioning as described in claim 1 weigh Herba Sarcandrae, Flos Chrysanthemi Indici, Radix Sophorae Flavescentis, Fructus Akebiae, Herba clerodendranthi spicati, Herba Patriniae, Herba Agrimoniae,
Herba Hedyotidis Diffusae, Radix Scutellariae, the 100 DEG C of heating of water adding 10 times amount are concentrated into original volume 1/5, and filter to get filtrate A；
2) proportioning as described in claim 1 takes Herba Artemisiae Annuae and Herba Leonuri, adds 10% ethanol solution and is placed in power 500W, frequency 80kHz
Ultrasonic container in extract 1h, filter, filtrate is placed in 60 DEG C volatilize solvent after, be mixed in filtrate A prepare.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610889602.6A CN106309749A (en) | 2016-10-12 | 2016-10-12 | Traditional Chinese medicine for treating cervical cancer |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610889602.6A CN106309749A (en) | 2016-10-12 | 2016-10-12 | Traditional Chinese medicine for treating cervical cancer |
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| CN106309749A true CN106309749A (en) | 2017-01-11 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110507734A (en) * | 2019-09-21 | 2019-11-29 | 王冶 | A kind of Chinese medicine composition of auxiliary treatment of cervical carcinoma and preparation method thereof |
| CN112426500A (en) * | 2020-08-15 | 2021-03-02 | 仲崇允 | Traditional Chinese medicine composition for treating cervical cancer |
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| CN102671129A (en) * | 2012-05-21 | 2012-09-19 | 唐武 | Traditional Chinese medicine compound for treating cervical cancer |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110507734A (en) * | 2019-09-21 | 2019-11-29 | 王冶 | A kind of Chinese medicine composition of auxiliary treatment of cervical carcinoma and preparation method thereof |
| CN112426500A (en) * | 2020-08-15 | 2021-03-02 | 仲崇允 | Traditional Chinese medicine composition for treating cervical cancer |
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