CN104547379A - Mint buccal tablet and preparation method thereof - Google Patents
Mint buccal tablet and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a mint buccal tablet and a preparation method thereof. The mint buccal tablet is prepared by the following methods: (1) taking agastache leaves, leaves of fortune eupatorium herbs, pericarpium citri reticulatae chachiensis, rhizoma pinelliae preparata, areca peel, officinal magnolia barks and lotus leaves, decocting with water, extracting and filtering to obtain filtrate, concentrating the filtrate to obtain an extract, adding ethyl alcohol to the extract for alcohol precipitation, performing still standing, taking supernate and concentrating the supernate to obtain an extract with the relative density of 1.20; (2) adding a brilliant blue pigment solution and a sodium carboxymethylcellulose solution to the obtained extract, and mixing to prepare extract mixed liquor; (3) mixing cane sugar powder, dextrin and soluble starch to obtain a mixture, adding the extract mixed liquor to the mixture and stirring to obtain a soft material, and pelletizing the soft material to obtain a pellet material; (4) adding mentol, peppermint oil, an ethanol solution of borneol, talcum powder and magnesium stearate to the pellet material, uniformly mixing and then tightly covering for 7-9 h, and tabletting to obtain the mint buccal tablets. When the mint buccal tablet disclosed by the invention is used for relieving chest and abdominal distention, removing halitosis and freshening the breath, and the effects are remarkable; the mint buccal tablet is convenient to carry and take.
Description
Technical field
The invention belongs to pharmaceutical technology sectors, be specifically related to a kind of tabellae menthae gurgitis, also relate to a kind of preparation method of tabellae menthae gurgitis simultaneously.
Background technology
Buccal tablet is a kind of administering mode of novelty, successful good with its mouthfeel, be easy to carry, easy to use and deeply to like by consumers in general.As Herba Pileae Scriptae Tabellae (having another name called FUFANG CAOSHANHU HANPIAN) is applicable to laryngopharynx swelling and pain, hoarseness and aphonia, acute pharyngolaryngitis caused by affection due to external wind and heat, belong to the buccal tablet medicament that wind heat disease person uses, be made up of Herba Sarcandrae extractum, Mentholum, peppermint wet goods).Waterelon Frost Lozenges effect is sore throat relieving sore-throat relieving, reducing swelling and alleviating pain, for preventing and treating laryngopharynx swelling and pain, and hoarseness, sore throat, aphtha of the mouth and tongue; Acute and chronic pharyngolaryngitis, acute tonsillitis, oral ulcer, stomatitis, gingival swelling and pain; Be made up of watermelon crystal, Borneolum Syntheticum, Oleum menthae, Mentholum, dextrin, sucrose etc.JINSANGZIHOUBAO energy wind and heat dispersing, antihalitosis, removing toxic substances and promoting subsidence of swelling, relieving sore throat and pain, be applicable to the symptoms such as laryngopharynx swelling and pain, hoarseness, acute pharyngitis, acute laryngitis; Make primarily of Herba Menthae, Flos Lonicerae, Fructus Momordicae etc.Effect that the said goods is had nothing in common with each other, and Herba Menthae property is pungent, cool, has dispelling wind-heat, the clear sharp head, sore-throat relieving, rash, the effect of dispersing the stagnated live-QI to relieve the stagnation of QI; Cure mainly wind heat to characterize, headache conjunctival congestion, laryngopharynx swelling and pain, measles without adequate eruption, rubella pruritus, hypochondriac pain due to stagnation of liverQI, how Herba Menthae made one there is relieving and eliminating mass, dispel halitosis, fresh breath effect containing agent, be the problem needing to solve.
Summary of the invention
The object of this invention is to provide a kind of there is relieving and eliminating mass, dispel halitosis, the tabellae menthae gurgitis of fresh breath effect.
Another object of the present invention is to provide a kind of preparation method of tabellae menthae gurgitis.
In order to realize above object, the technical solution adopted in the present invention is:
A kind of tabellae menthae gurgitis is prepared by the method comprised the following steps:
1) Radix agastaches, Folium Eupatorii, Pericarpium citri reticuatae chachiensis, Rhizoma Pinelliae, Pericarpium Arecae, Cortex Magnoliae Officinalis(processed with ginger), Folium Nelumbinis is got, decocting filters after extracting, get filtrate and be concentrated into the extractum that relative density is 1.15, add after ethanol carries out precipitate with ethanol in gained extractum, leave standstill, get supernatant concentration and obtain the extractum that relative density is 1.20;
2) to step 1) gained relative density is add sapphirine cellulose solution and carboxymethylcellulose sodium solution in the extractum of 1.20, is mixed and made into extractum mixed liquor;
3), after getting the mixing of cane sugar powder, dextrin and soluble starch, step 2 is added) gained extractum mixed liquor, stir after making soft material, wet granular processed drying, granulate, obtain a material;
4) to step 3) add Mentholum, Oleum menthae, the alcoholic solution of Borneolum Syntheticum, Pulvis Talci, magnesium stearate in gained grain material, after mix homogeneously, vexed 7 ~ 9h, tabletting, to obtain final product.
Step 1) in, the raw material of Chinese medicine that described decocting extracts is counted by weight: Radix agastaches 100 parts, Folium Eupatorii 100 parts, Pericarpium citri reticuatae chachiensis 50 parts, Rhizoma Pinelliae Preparata 50 parts, Pericarpium Arecae 100 parts, Cortex Magnoliae Officinalis(processed with ginger) 80 parts, 30 parts, Folium Nelumbinis.
Step 1) in, described decocting is extracted as extracting in water secondary, and amount of water is 10 times of raw material of Chinese medicine quality for the first time, and extraction time is 1.5h; Second time amount of water is 8 times of raw material of Chinese medicine quality, and extraction time is 1.0h.
Step 1) in, the amount that described precipitate with ethanol adds ethanol to be relative density be 1.15 extractum volume qdx.
Step 1) in, the described standing time is 24h.
Step 1) in, described leave standstill after, get supernatant, reclaim ethanol and concentrated that relative density is the extractum of 1.20.
Step 2) in, described light blue pigment to add quality be relative density is 0.04% of the extractum quality of 1.20; The addition of described sodium carboxymethyl cellulose is relative density is 5% of the extractum quality of 1.20.
Step 2) in, in described sapphirine cellulose solution, the mass percentage of light blue pigment is 1.0% ~ 2.0%.In described carboxymethylcellulose sodium solution, the mass percentage of sodium carboxymethyl cellulose is 10%.
The viscosity of described carboxymethylcellulose sodium solution is 300 ~ 600mPas.
Step 3) in, the consumption of described cane sugar powder, dextrin, soluble starch is counted by weight: cane sugar powder 600 ~ 800 parts, 100 parts, dextrin, soluble starch 100 parts; The amount simultaneously adding extractum mixed liquor is 1:1 for making the mass ratio of the Radix agastaches in raw material of Chinese medicine and dextrin.
Step 3) in, described drying is employing 60 ~ 70 DEG C of hot air dryings, and the water content being dried to granule is less than 5%.
Step 4) in, add that quality is described grain material amount 0.4% of described Mentholum; Add that quality is described grain material amount 0.4% of described Oleum menthae.
Step 4) in, described talcous add that quality is described grain material amount 1.5%; Add that quality is described grain material amount 0.75% of described magnesium stearate; Add that quality is described grain material amount 0.5% ~ 1.0% of the alcoholic solution of described Borneolum Syntheticum, in the alcoholic solution of described Borneolum Syntheticum, the mass percentage of Borneolum Syntheticum is 20%.
A preparation method for tabellae menthae gurgitis, comprises the following steps:
1) Radix agastaches, Folium Eupatorii, Pericarpium citri reticuatae chachiensis, Rhizoma Pinelliae, Pericarpium Arecae, Cortex Magnoliae Officinalis(processed with ginger), Folium Nelumbinis is got, decocting filters after extracting, get filtrate and be concentrated into the extractum that relative density is 1.15, add after ethanol carries out precipitate with ethanol in gained extractum, leave standstill, get supernatant concentration and obtain the extractum that relative density is 1.20;
2) to step 1) gained relative density is add sapphirine cellulose solution and carboxymethylcellulose sodium solution in the extractum of 1.20, is mixed and made into extractum mixed liquor;
3), after getting the mixing of cane sugar powder, dextrin and soluble starch, step 2 is added) gained extractum mixed liquor, stir after making soft material, wet granular processed drying, granulate, obtain a material;
4) to step 3) add Mentholum, Oleum menthae, the alcoholic solution of Borneolum Syntheticum, Pulvis Talci, magnesium stearate in gained grain material, after mix homogeneously, vexed 7 ~ 9h, tabletting, to obtain final product.
In tabellae menthae gurgitis of the present invention, effect of each raw material of Chinese medicine is as follows:
Radix agastaches: property is pungent, tepor; There is antibacterial, anti-spirillum and antivirus action; Dispelling summer-heat from superficies of the body, removing dampness to restore normal function of the stomach; Cure mainly summertime flu, cold and heat are had a headache, and breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, vomiting during pregnancy, nasal sinusitis, hands, tinea pedis.
Folium Eupatorii: property is pungent, flat; Have eliminate the phlegm, antiviral, antitumaous effect; Expelling summer-heat and damp, be amusing and in; Cure mainly heat-damp in summer or hygropyrexia from the beginning of, generate heat nose heave, abdominal distention uncomfortable in chest, the not hungry nausea and vomiting of gastral cavity painful abdominal mass, sweet greasy in mouth, quench one's thirst.
Pericarpium Citri Reticulatae: property is pungent, bitter, temperature; Regulate the flow of vital energy in adjusting, stopping nausea and vomiting by lowering the adverse flow of QI, drying dampness to eliminate phlegm; Cure mainly chest and diaphragm full vexed, abdominal distention, anorexia, vomiting, cough with copious phlegm.Pericarpium citri reticuatae chachiensis is the ground peel such as Citrus reticulata Blanco cv. Chachiensis, four meeting Citrus chachiensiss Hort., and originate in the ground such as Xinhui of Guangdong Province, four meetings, quality is good.
The Rhizoma Pinelliae: property is pungent, warm; There is antitussive, phlegm-dispelling functions; Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Cure mainly cough with asthma abundant expectoration, vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium, has a headache dizzy, uneasy sleeping at night, gall subcutaneous nodule, swollen ulcer drug.Rhizoma Pinelliae, for concoct the Rhizoma Pinelliae with vitriol, is eliminated the side effect of its pungent thorn larynx, is reduced toxicity, based on drying dampness to eliminate phlegm.
Pericarpium Arecae: property is pungent, tepor; Have and promote digestive tract power effect; Therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, line water detumescence; Cure mainly breast abdominal distention vexed, edema, beriberi, dysuria.
Cortex Magnoliae Officinalis: property is bitter, pungent, temperature; Circulation of qi promoting intestinal stasis relieving, dampness, lowering the adverse QI to relieve asthma; Cure mainly stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant stops up QI rising in reverse order, and fullness in the chest is breathed with cough.Cortex Magnoliae Officinalis(processed with ginger) concocts Cortex Magnoliae Officinalis for adopting Sucus Zingberis, and processed with Rhizoma Zingiberis Recens can eliminate the stimulation of Cortex Magnoliae Officinalis to throat, and strengthens effect of alleviating distention in middle-JIAO stomach function regulating.
Folium Nelumbinis: property is bitter, puckery is flat; Clearing away summer-heat, yang invigorating, hemostasis; Cure mainly summer-heat excessive thirst, have a headache dizzy, splenasthenic abdominal distention.
Tabellae menthae gurgitis of the present invention, adopt Radix agastaches, Folium Eupatorii, Pericarpium citri reticuatae chachiensis, Rhizoma Pinelliae, Pericarpium Arecae, Cortex Magnoliae Officinalis(processed with ginger), Folium Nelumbinis water extract-alcohol precipitation extractum, with light blue pigment, sodium carboxymethyl cellulose, and after cane sugar powder, dextrin and soluble starch mixing granulation, again with alcoholic solution, Pulvis Talci, the magnesium stearate mixed pressuring plate of Mentholum, Oleum menthae, Borneolum Syntheticum, gained tablet is buccal tablet (containing agent), for relieving and eliminating mass, dispel halitosis, fresh breath, be convenient for carrying, be convenient to take; Be applicable to clinical treatment early stage, light-duty optimum pharyngitis, tonsillitis and chronic pharyngitis, tonsillitis, laryngitis and oral mucosa inflammation, also can be used as treatment serious symptom pharyngitis, tonsillitic drug combination.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is further illustrated.
Embodiment 1
The tabellae menthae gurgitis of the present embodiment is prepared by the method comprised the following steps:
1) raw material of Chinese medicine Radix agastaches 100 weight portion, Folium Eupatorii 100 weight portion, Pericarpium citri reticuatae chachiensis 50 weight portion, Rhizoma Pinelliae 50 weight portion, Pericarpium Arecae 100 weight portion, Cortex Magnoliae Officinalis(processed with ginger) 80 weight portion, Folium Nelumbinis 30 weight portion is got, decocting extracts secondary, amount of water is 10 times of raw material of Chinese medicine quality for the first time, and extraction time is 1.5h; Second time amount of water is 8 times of raw material of Chinese medicine quality, extraction time is 1.0h, filter after extracting, merging filtrate, get filtrate and be concentrated into the extractum that relative density is 1.15, after the ethanol adding extractum volume qdx in gained extractum carries out precipitate with ethanol, after leaving standstill 24h, get supernatant, reclaim ethanol and concentrate relative density is the extractum of 1.20;
2) to step 1) gained relative density is add sapphirine cellulose solution and carboxymethylcellulose sodium solution in the extractum of 1.20, is fully uniformly mixed and makes extractum mixed liquor; Described light blue pigment to add quality be relative density is 0.04% of the extractum quality of 1.20, in described sapphirine cellulose solution, the mass percentage of light blue pigment is 1%; The addition of described sodium carboxymethyl cellulose is relative density is 5% of the extractum quality of 1.20, and in described carboxymethylcellulose sodium solution, the mass percentage of sodium carboxymethyl cellulose is 10%;
3) in trough type mixing machine, add cane sugar powder 800 weight portion, dextrin 100 weight portion, soluble starch 100 weight portion, after being uniformly mixed 5min, add step 2) gained extractum mixed liquor, after soft material is made in stirring, make to make wet granular by 16 eye mesh screens, the water content that 60 DEG C of heated-air circulation ovens are dried to granule is less than 5%, and granulate, obtains a material;
4) to step 3) add Mentholum (add 0.4% that quality is described grain material amount) in gained grain material, Oleum menthae (add 0.4% that quality is described grain material amount), the alcoholic solution of Borneolum Syntheticum (add that quality is described grain material amount 0.5% of the alcoholic solution of Borneolum Syntheticum, in the alcoholic solution of described Borneolum Syntheticum, the mass percentage of Borneolum Syntheticum is 20%), Pulvis Talci (add 1.5% that quality is described grain material amount), magnesium stearate (add 0.75% that quality is described grain material amount), in mixer after mix homogeneously, after vexed 7h, gained granule is pressed into tablet in tablet machine, quality inspection, packaging, obtain described tabellae menthae gurgitis.
Embodiment 2
The tabellae menthae gurgitis of the present embodiment is prepared by the method comprised the following steps:
1) raw material of Chinese medicine Radix agastaches 100 weight portion, Folium Eupatorii 100 weight portion, Pericarpium citri reticuatae chachiensis 50 weight portion, Rhizoma Pinelliae 50 weight portion, Pericarpium Arecae 100 weight portion, Cortex Magnoliae Officinalis(processed with ginger) 80 weight portion, Folium Nelumbinis 30 weight portion is got, decocting extracts secondary, amount of water is 10 times of raw material of Chinese medicine quality for the first time, and extraction time is 1.5h; Second time amount of water is 8 times of raw material of Chinese medicine quality, extraction time is 1.0h, filter after extracting, merging filtrate, get filtrate and be concentrated into the extractum that relative density is 1.15, after the ethanol adding extractum volume qdx in gained extractum carries out precipitate with ethanol, after leaving standstill 24h, get supernatant, reclaim ethanol and concentrate relative density is the extractum of 1.20;
2) to step 1) gained relative density is add sapphirine cellulose solution and carboxymethylcellulose sodium solution in the extractum of 1.20, is fully uniformly mixed and makes extractum mixed liquor; Described light blue pigment to add quality be relative density is 0.04% of the extractum quality of 1.20, in described sapphirine cellulose solution, the mass percentage of light blue pigment is 1.5%; The addition of described sodium carboxymethyl cellulose is relative density is 5% of the extractum quality of 1.20, and in described carboxymethylcellulose sodium solution, the mass percentage of sodium carboxymethyl cellulose is 10%;
3) in trough type mixing machine, add cane sugar powder 700 weight portion, dextrin 100 weight portion, soluble starch 100 weight portion, after being uniformly mixed 5min, add step 2) gained extractum mixed liquor, after soft material is made in stirring, make to make wet granular by 16 eye mesh screens, the water content that 70 DEG C of heated-air circulation ovens are dried to granule is less than 5%, and granulate, obtains a material;
4) to step 3) add Mentholum (add 0.4% that quality is described grain material amount) in gained grain material, Oleum menthae (add 0.4% that quality is described grain material amount), the alcoholic solution of Borneolum Syntheticum (add that quality is described grain material amount 1.0% of the alcoholic solution of Borneolum Syntheticum, in the alcoholic solution of described Borneolum Syntheticum, the mass percentage of Borneolum Syntheticum is 20%), Pulvis Talci (add 1.5% that quality is described grain material amount), magnesium stearate (add 0.75% that quality is described grain material amount), in mixer after mix homogeneously, after vexed 8h, gained granule is pressed into tablet in tablet machine, quality inspection, packaging, obtain described tabellae menthae gurgitis.
Embodiment 3
The tabellae menthae gurgitis of the present embodiment is prepared by the method comprised the following steps:
1) raw material of Chinese medicine Radix agastaches 100 weight portion, Folium Eupatorii 100 weight portion, Pericarpium citri reticuatae chachiensis 50 weight portion, Rhizoma Pinelliae 50 weight portion, Pericarpium Arecae 100 weight portion, Cortex Magnoliae Officinalis(processed with ginger) 80 weight portion, Folium Nelumbinis 30 weight portion is got, decocting extracts secondary, amount of water is 10 times of raw material of Chinese medicine quality for the first time, and extraction time is 1.5h; Second time amount of water is 8 times of raw material of Chinese medicine quality, extraction time is 1.0h, filter after extracting, merging filtrate, get filtrate and be concentrated into the extractum that relative density is 1.15, after the ethanol adding extractum volume qdx in gained extractum carries out precipitate with ethanol, after leaving standstill 24h, get supernatant, reclaim ethanol and concentrate relative density is the extractum of 1.20;
2) to step 1) gained relative density is add sapphirine cellulose solution and carboxymethylcellulose sodium solution in the extractum of 1.20, is fully uniformly mixed and makes extractum mixed liquor; Described light blue pigment to add quality be relative density is 0.04% of the extractum quality of 1.20, in described sapphirine cellulose solution, the mass percentage of light blue pigment is 2.0%; The addition of described sodium carboxymethyl cellulose is relative density is 5% of the extractum quality of 1.20, and in described carboxymethylcellulose sodium solution, the mass percentage of sodium carboxymethyl cellulose is 10%;
3) in trough type mixing machine, add cane sugar powder 600 weight portion, dextrin 100 weight portion, soluble starch 100 weight portion, after being uniformly mixed 5min, add step 2) gained extractum mixed liquor, after soft material is made in stirring, make to make wet granular by 16 eye mesh screens, the water content that 70 DEG C of heated-air circulation ovens are dried to granule is less than 5%, and granulate, obtains a material;
4) to step 3) add Mentholum (add 0.4% that quality is described grain material amount) in gained grain material, Oleum menthae (add 0.4% that quality is described grain material amount), the alcoholic solution of Borneolum Syntheticum (add that quality is described grain material amount 0.75% of the alcoholic solution of Borneolum Syntheticum, in the alcoholic solution of described Borneolum Syntheticum, the mass percentage of Borneolum Syntheticum is 20%), Pulvis Talci (add 1.5% that quality is described grain material amount), magnesium stearate (add 0.75% that quality is described grain material amount), in mixer after mix homogeneously, after vexed 9h, gained granule is pressed into tablet in tablet machine, quality inspection, packaging, obtain described tabellae menthae gurgitis.
Claims (10)
1. a tabellae menthae gurgitis, is characterized in that: be prepared by the method comprised the following steps:
1) Radix agastaches, Folium Eupatorii, Pericarpium citri reticuatae chachiensis, Rhizoma Pinelliae, Pericarpium Arecae, Cortex Magnoliae Officinalis(processed with ginger), Folium Nelumbinis is got, decocting filters after extracting, get filtrate and be concentrated into the extractum that relative density is 1.15, add after ethanol carries out precipitate with ethanol in gained extractum, leave standstill, get supernatant concentration and obtain the extractum that relative density is 1.20;
2) to step 1) gained relative density is add sapphirine cellulose solution and carboxymethylcellulose sodium solution in the extractum of 1.20, is mixed and made into extractum mixed liquor;
3), after getting the mixing of cane sugar powder, dextrin and soluble starch, step 2 is added) gained extractum mixed liquor, stir after making soft material, wet granular processed drying, granulate, obtain a material;
4) to step 3) add Mentholum, Oleum menthae, the alcoholic solution of Borneolum Syntheticum, Pulvis Talci, magnesium stearate in gained grain material, after mix homogeneously, vexed 7 ~ 9h, tabletting, to obtain final product.
2. tabellae menthae gurgitis according to claim 1, it is characterized in that: step 1) in, the raw material of Chinese medicine that described decocting extracts is counted by weight: Radix agastaches 100 parts, Folium Eupatorii 100 parts, Pericarpium citri reticuatae chachiensis 50 parts, Rhizoma Pinelliae Preparata 50 parts, Pericarpium Arecae 100 parts, Cortex Magnoliae Officinalis(processed with ginger) 80 parts, 30 parts, Folium Nelumbinis.
3. tabellae menthae gurgitis according to claim 1 and 2, is characterized in that: step 1) in, described decocting is extracted as extracting in water secondary, and amount of water is 10 times of raw material of Chinese medicine quality for the first time, and extraction time is 1.5h; Second time amount of water is 8 times of raw material of Chinese medicine quality, and extraction time is 1.0h.
4. tabellae menthae gurgitis according to claim 1, is characterized in that: step 1) in, the amount that described precipitate with ethanol adds ethanol to be relative density be 1.15 extractum volume qdx.
5. tabellae menthae gurgitis according to claim 1, is characterized in that: step 2) in, described light blue pigment to add quality be relative density is 0.04% of the extractum quality of 1.20; The addition of described sodium carboxymethyl cellulose is relative density is 5% of the extractum quality of 1.20.
6. tabellae menthae gurgitis according to claim 1, is characterized in that: step 3) in, the consumption of described cane sugar powder, dextrin, soluble starch is counted by weight: cane sugar powder 600 ~ 800 parts, 100 parts, dextrin, soluble starch 100 parts; The amount simultaneously adding extractum mixed liquor is 1:1 for making the mass ratio of the Radix agastaches in raw material of Chinese medicine and dextrin.
7. tabellae menthae gurgitis according to claim 1, is characterized in that: step 3) in, described drying is employing 60 ~ 70 DEG C of hot air dryings, and the water content being dried to granule is less than 5%.
8. tabellae menthae gurgitis according to claim 1, is characterized in that: step 4) in, add that quality is described grain material amount 0.4% of described Mentholum; Add that quality is described grain material amount 0.4% of described Oleum menthae.
9. the tabellae menthae gurgitis according to claim 1 or 8, is characterized in that: step 4) in, described talcous add that quality is described grain material amount 1.5%; Add that quality is described grain material amount 0.75% of described magnesium stearate; Add that quality is described grain material amount 0.5% ~ 1.0% of the alcoholic solution of described Borneolum Syntheticum, in the alcoholic solution of described Borneolum Syntheticum, the mass percentage of Borneolum Syntheticum is 20%.
10. a preparation method for tabellae menthae gurgitis, is characterized in that: comprise the following steps:
1) Radix agastaches, Folium Eupatorii, Pericarpium citri reticuatae chachiensis, Rhizoma Pinelliae, Pericarpium Arecae, Cortex Magnoliae Officinalis(processed with ginger), Folium Nelumbinis is got, decocting filters after extracting, get filtrate and be concentrated into the extractum that relative density is 1.15, add after ethanol carries out precipitate with ethanol in gained extractum, leave standstill, get supernatant concentration and obtain the extractum that relative density is 1.20;
2) to step 1) gained relative density is add sapphirine cellulose solution and carboxymethylcellulose sodium solution in the extractum of 1.20, is mixed and made into extractum mixed liquor;
3), after getting the mixing of cane sugar powder, dextrin and soluble starch, step 2 is added) gained extractum mixed liquor, stir after making soft material, wet granular processed drying, granulate, obtain a material;
4) to step 3) add Mentholum, Oleum menthae, the alcoholic solution of Borneolum Syntheticum, Pulvis Talci, magnesium stearate in gained grain material, after mix homogeneously, vexed 7 ~ 9h, tabletting, to obtain final product.
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| RU2616905C1 (en) * | 2015-10-20 | 2017-04-18 | Вячеслав Вениаминович Костин | Method of medicinal herb tabletting |
| CN114468094A (en) * | 2022-01-25 | 2022-05-13 | 深圳市宝安区中医院 | Dampness eliminating tea and preparation method thereof |
| CN114468094B (en) * | 2022-01-25 | 2024-04-12 | 深圳市宝安区中医院 | Dampness eliminating tea and preparation method thereof |
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