CN104547352A - Pharmaceutical composition for treating facioplegia - Google Patents

Pharmaceutical composition for treating facioplegia Download PDF

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CN104547352A
CN104547352A CN201510039947.8A CN201510039947A CN104547352A CN 104547352 A CN104547352 A CN 104547352A CN 201510039947 A CN201510039947 A CN 201510039947A CN 104547352 A CN104547352 A CN 104547352A
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pharmaceutical composition
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herba
folium
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张小凤
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Abstract

The invention relates to a pharmaceutical composition for treating facioplegia. The pharmaceutical composition consists of the following traditional Chinese medicine raw materials by weight: 5-10g of xylocopa, 3-8g of cedar leaves, 3-5g of marigold, 5-15g of rhizoma acori graminei, 3-5g of fourleaf peperomia herb, 2-5g of fewflower lysionotus herb, 5-10g of lindera glauca root, 3-5g of cissus pteroclada hayata, 3-8g of Japanese creeper root and stem, 2-5g of corydalis amabilis, 5-20g of loofah sponge, 5-20g of the root of red-rooted salvia, 3-8g of actinidia polygama and 3-5g of ventilago leiocarpa benth. The pure traditional Chinese medicine raw materials are adopted, the pharmaceutical composition has the effects of dispelling pathogenic wind and eliminating phlegm, promoting blood circulation to remove meridian obstruction and invigorating qi and blood, is obvious in curative effect of facioplegia caused by facial neuritis, is high in cure rate and does not have any toxic or side effect during external application, the sequelae are not remained, and the disease does not reoccur.

Description

Treat prosopoplegic pharmaceutical composition
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to one and treat prosopoplegic pharmaceutical composition.
Background technology
Facial paralysis, is commonly called as " facial paralysis ", " wapperijaw bar ", " facial paralysis ", is a kind of commonly encountered diseases that is principal character with facial expression muscle group dyskinesia.General symptom is facial hemiparalysis.It is a kind of commonly encountered diseases, frequently-occurring disease, and it is not by age limit.Be principal character with facial hemiparalysis clinically, mostly be Unilateral, it is few that bilateral is fallen ill simultaneously.Onset is anxious, and sick side surface part histrionic muscles paralysis, forehead line disappears, and eyebrow is sagging, blepharodiastasis, and nasolabial fold is smooth, ptosis of labial angle, and face is led to strong side.Primary disease is commonly encountered diseases, the frequently-occurring disease of Neurological Clinics, and any age all can fall ill, but the most common with 20 ~ 40 years old.Any season all can fall ill.Facial paralysis the lighter, and treat in time, prognosis is better; The facial paralysis persistent period is longer, and prognosis is poorer.
Cause the prosopoplegic cause of disease to have multiple, be mainly caused by heresy invasion and attack that Head And Face has a cold, cause muscle arteries and veins to lose and support and cause, be divided into maincenter profile neural paralysis and peripheral profiles neural paralysis two kinds clinically.Commonly encountered diseases because: 1. infection, many being activated by the varicella zoster virus of resting state in nervus facialis sensory ganglion of hiding of infection causes; 2. ear source property disease, 3. autoimmune response; 4. tumor; 5. neurogenic; 6. traumatic; 7. poisoning, as alcoholism, Long Term Contact Toxic; 8. dysbolismus, as diabetes, vitamin deficiency; 9. vascular function is incomplete; 10. congenital nuclear agenesis.
The traditional Chinese medical science is thought, primary disease belongs to " apoplexy " category, and for patient is when tired and physically-draining, healthy energy is relatively empty in interior, and venation is hollow, the heresy invasion and attack that Head And Face is had a cold, and causes blockage of meridian, and QI and blood numbness resistance meridians, the mistake of muscle arteries and veins is foster, and sees all diseases of facial hemiparalysis.
Western medical treatment improves local blood circulation, alleviates nervus facialis edema, alleviates nerve compression, promotes the medicine of neurological functional recovery, the Drug therapys such as such as prednisone, dexamethasone, vitamin B group, bendazol, neostigmine, galantamine; Mostly the traditional Chinese medical science is with acupuncture or the treatment of prescription QIANZHENGSAN.But patient can leave sequela more afterwards, and relapse rate is high.
Summary of the invention
The object of the present invention is to provide a kind of determined curative effect, cure rate is high, not easily recurs, the prosopoplegic pharmaceutical composition of the treatment had no side effect.
The technical solution adopted for the present invention to solve the technical problems is: treat prosopoplegic pharmaceutical composition, is made up of the raw material of Chinese medicine of following weight proportioning: Xylocopa dissimilis (Lep.) 5-10g, Folium Cunninghamiae lanceolatae 3-8g, Flos Tagetis Erectae 3-5g, Rhizoma Acori Graminei 5-15g, Herba Seu Radix Peperomiae Tetraphyllae 3-5g, Herba Lysionoti Pauciflori 2-5g, Radix Linderae Glaucae 5-10g, Cissus pteroclada Hayata 3-5g, Radix seu Caulis Parthenocissi tricuspidatae 3-8g, Rhizoma Corydalis Decumbentis 2-5g, Retinervus Luffae Fructus 5-20g, Radix Salviae Miltiorrhizae 5-20g, Ramulus et Folium Actinidiae Polygamae 3-8g, Radix seu Caulis Verntilaginis Leiocarpae 3-5g.
Treat prosopoplegic pharmaceutical composition, be made up of the raw material of Chinese medicine of following weight proportioning: Xylocopa dissimilis (Lep.) 8g, Folium Cunninghamiae lanceolatae 5g, power longevity chrysanthemum 5g, Rhizoma Acori Graminei 10g, Herba Seu Radix Peperomiae Tetraphyllae 3g, Herba Lysionoti Pauciflori 3g, Radix Linderae Glaucae 5g, Cissus pteroclada Hayata 5g, Radix seu Caulis Parthenocissi tricuspidatae 5g, Rhizoma Corydalis Decumbentis 4g, Retinervus Luffae Fructus 10g, Radix Salviae Miltiorrhizae 15g, Ramulus et Folium Actinidiae Polygamae 5g, Radix seu Caulis Verntilaginis Leiocarpae 4g.
The pharmacologically active of each raw material of Chinese medicine of the present invention is as follows:
Xylocopa dissimilis (Lep.) is the Scorpio of Apidae insecticide Xylocopa dissimilis (Lep.), and sweet in the mouth is cold in nature, returns stomach, large intestine channel, removing heat-phlegm; Arresting convulsion.Main infantile convulsion; Edema due to wind pathogen pain is swollen; Tonsillitis; Aphtha." Luchuan book on Chinese herbal medicine ": dispelling pathogenic wind and eliminating phlegm, promoting the circulation of QI for relieving swelling, controls wind-phlegm and closes key, asthma abdominal distention, edema due to wind pathogen edema, acute infantile convulsion.
Folium Cunninghamiae lanceolatae, be tender leaf or the blade of taxodiaceae plant China fir, pungent, slightly warm in nature, dispels the wind; Reduce phlegm; Invigorate blood circulation; Removing toxic substances.Main hemiplegia from the beginning of; Rubella; Cough; Toothache; Pemphigus; Impetigo; Fungal infection of hand and foot; Traumatic injury; Insect-bite.
Flos Tagetis Erectae is the inflorescence of feverfew Flos Tagetis Erectae, and bitter, cool, calming liver and clearing heat, dispels the wind, and reduces phlegm.Control and have a dizzy spell, acute conjunctivitis due to pathogenic windfire, infantile convulsion, cold cough, pertussis, acute mastitis, mumps.
Rhizoma Acori Graminei is the rhizome of South, sky section phytobezoar Rhizoma Acori Graminei, pungent, bitter, temperature, GUIXIN, stomach warp, and removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Not hungry for gastral cavity painful abdominal mass, a mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.
Herba Seu Radix Peperomiae Tetraphyllae is herb or the root of Piperaceae plant Herba Seu Radix Peperomiae Tetraphyllae, pungent, and bitter, tepor, returns lung, liver, spleen channel, relaxing muscles and tendons to promote blood circulation; Expelling wind and removing dampness; Preventing phlegm from forming and stopping coughing.Main bones and muscles pain due to rheumatism; Traumatic injury; Furuncle toxic swelling; Pharyngolaryngitis; Stomatitis; Dysentery; Watery diarrhea; Dyspepsia does not disappear; Infantile malnutrition; Epersalgia cough; Asthma; Pertussis.
Herba Lysionoti Pauciflori is the herb of Gesneriaceae Herba Lysionoti Pauciflori, and bitter in the mouth is pungent, and property is put down, expelling wind and removing dampness; Preventing phlegm from forming and stopping coughing; Blood stasis dispelling stimulates the menstrual flow.Main air pain of dampness syndrome; Cough with asthma abundant expectoration; Menoxenia; Dysmenorrhea; Traumatic injury.
Radix Linderae Glaucae is the root of canella tendon Bovis seu Bubali tree, pungent, and temperature is bitter, returns liver, stomach warp, dispelling wind and removing obstruction in the collateral; Vital energy regualting and blood circulation-promoting; Inducing diuresis and reducing edema; Preventing phlegm from forming and stopping coughing.Main air pain of dampness syndrome; Traumatic injury; Gastralgia; De-power impairment caused by overstrain; Bronchitis; Edema.
Cissus pteroclada Hayata is the stem of vitaceae Cissus pteroclada Hayata, pungent, micro-hardship, and property is put down, and returns Liver Channel, expelling wind and removing dampness; Promoting blood circulation to remove obstruction in the collateral.Main air pain of dampness syndrome; Lumbar muscle strain; Limb paralysis; Traumatic injury.
Radix seu Caulis Parthenocissi tricuspidatae is root and the stem of vitaceae parthenocissus, and acrid in the mouth is micro-puckery, warm in nature, returns Liver Channel, wind-expelling pain-stopping; Promoting blood circulation to remove obstruction in the collateral.Main air pain of dampness syndrome; Apoplexy and hemiplegia; Migraine and general headache; Puerperal blood stasis; The raw caking of abdomen; Traumatic injury; Carbuncle sore tumefacting virus; Ulcer being unable to heal.
Rhizoma Corydalis Decumbentis, bitter, micro-pungent, temperature, returns Liver Channel, expelling wind and removing dampness; Relaxing muscles and tendons to promote blood circulation; Removing obstruction in the collateral to relieve pain; Blood pressure lowering.Main air wet arthritis; Apoplectic hemiplegia; Sciatica; Poliomyelitis sequela; Lumbar muscle strain; Injury from falling down; Hypertension.
Retinervus Luffae Fructus is the reticular fiber of the old hot fruit of cucurbitaceous plant Fructus Luffae or the withered old fruit of Guangdong Fructus Luffae, dredge the meridian passage, removing heat-phlegm.Control pain in chest and hypochondrium, stomachache, lumbago, painful and swollen testis, lung-heat productive cough, women's amenorrhea, galactostasis, carbuncle, anal fistula.Charcoal: can stop blooding.Treating hematochezia, metrorrhagia.
Radix Salviae Miltiorrhizae is the root of labiate Radix Salviae Miltiorrhizae, and bitter, be slightly cold, GUIXIN, Liver Channel, stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris." choosing of Yunnan Chinese herbal medicine ": " promoting blood circulation to remove blood stasis, sedation-analgesia.Control menoxenia, dysmenorrhea, rheumatic arthralgia, metrorrhagia, spit blood, mastitis, carbuncle.″
Ramulus et Folium Actinidiae Polygamae is the fruit with insect gall of macaque Chinese scholartree section plant Ramulus et Folium Actinidiae Polygamae, pungent; Bitter; Warm in nature, return liver, kidney channel, dispelling wind and removing obstruction in the collateral; Blood-activating and qi-promoting; Dispersing cold for relieving pain.In the main tuyere surface skew;Xuan fetish pain;A hernia." property of medicine opinion ": " control middle harmful wind, facial palsy, main cold mass beside the umbilicus air parcel, woman's asthenia.″
Radix seu Caulis Verntilaginis Leiocarpae is root, the stem of Rhamnaceae plant ventilago leiocarpa, sweet, and temperature, returns lung, spleen channel, fill blood, bone and muscle strengthening; Relax meridians.Main deficient qi and blood; Have through uncomfortable; Blood deficiency amenorrhea; Rheumatalgia; Traumatic injury; Lumbar muscle strain.Guangzhou army " conventional Chinese herbal medicine handbook ": " rich in nutrition, relaxing muscles and tendons and activating QI and blood in the collateral.Control deficiency of both QI and blood, menoxenia, bones and muscles pain due to rheumatism, numb limbs and tense tendons, traumatic injury.″
The present invention has following beneficial effect: pharmaceutical composition of the present invention adopts pure raw material of Chinese medicine, has effect of dispelling pathogenic wind and eliminating phlegm, promoting blood circulation to remove obstruction in the collateral, benefiting vital QI and blood, and the facial paralysis caused facial neuritis is evident in efficacy, cure rate is high, do not stay sequela, do not recur, external application has no side effect.
Detailed description of the invention
Be below specific embodiments of the invention, technical scheme of the present invention is described further, but protection scope of the present invention is not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
Embodiment 1
Treat prosopoplegic pharmaceutical composition, be made up of the raw material of Chinese medicine of following weight proportioning: Xylocopa dissimilis (Lep.) 5g, Folium Cunninghamiae lanceolatae 8g, power longevity chrysanthemum 4g, Rhizoma Acori Graminei 15g, Herba Seu Radix Peperomiae Tetraphyllae 4g, Herba Lysionoti Pauciflori 5g, Radix Linderae Glaucae 8g, Cissus pteroclada Hayata 4g, Radix seu Caulis Parthenocissi tricuspidatae 3g, Rhizoma Corydalis Decumbentis 3g, Retinervus Luffae Fructus 15g, Radix Salviae Miltiorrhizae 10g, Ramulus et Folium Actinidiae Polygamae 8g, Radix seu Caulis Verntilaginis Leiocarpae 5g.
Embodiment 2
Treat prosopoplegic pharmaceutical composition, be made up of the raw material of Chinese medicine of following weight proportioning: Xylocopa dissimilis (Lep.) 8g, Folium Cunninghamiae lanceolatae 5g, power longevity chrysanthemum 5g, Rhizoma Acori Graminei 10g, Herba Seu Radix Peperomiae Tetraphyllae 3g, Herba Lysionoti Pauciflori 3g, Radix Linderae Glaucae 5g, Cissus pteroclada Hayata 5g, Radix seu Caulis Parthenocissi tricuspidatae 5g, Rhizoma Corydalis Decumbentis 4g, Retinervus Luffae Fructus 10g, Radix Salviae Miltiorrhizae 15g, Ramulus et Folium Actinidiae Polygamae 5g, Radix seu Caulis Verntilaginis Leiocarpae 4g.
Embodiment 3
Treat prosopoplegic pharmaceutical composition, be made up of the raw material of Chinese medicine of following weight proportioning: Xylocopa dissimilis (Lep.) 7g, Folium Cunninghamiae lanceolatae 3g, Flos Tagetis Erectae 4g, Rhizoma Acori Graminei 8g, Herba Seu Radix Peperomiae Tetraphyllae 4g, Herba Lysionoti Pauciflori 2g, Radix Linderae Glaucae 10g, Cissus pteroclada Hayata 3g, Radix seu Caulis Parthenocissi tricuspidatae 8g, Rhizoma Corydalis Decumbentis 5g, Retinervus Luffae Fructus 5g, Radix Salviae Miltiorrhizae 20g, Ramulus et Folium Actinidiae Polygamae 3g, Radix seu Caulis Verntilaginis Leiocarpae 4g.
Embodiment 4
Treat prosopoplegic pharmaceutical composition, be made up of the raw material of Chinese medicine of following weight proportioning: Xylocopa dissimilis (Lep.) 8g, Folium Cunninghamiae lanceolatae 5g, Flos Tagetis Erectae 5g, Rhizoma Acori Graminei 10g, Herba Seu Radix Peperomiae Tetraphyllae 3g, Herba Lysionoti Pauciflori 3g, Radix Linderae Glaucae 5g, Cissus pteroclada Hayata 5g, Radix seu Caulis Parthenocissi tricuspidatae 5g, Rhizoma Corydalis Decumbentis 4g, Retinervus Luffae Fructus 10g, Radix Salviae Miltiorrhizae 15g, Ramulus et Folium Actinidiae Polygamae 5g, Radix seu Caulis Verntilaginis Leiocarpae 4g.
Clinical data
Physical data: accept for medical treatment altogether prosopoplegic 197 example, wherein male 108 example, women 89 example, age 17-74 year, 40 years old mean age.
Diagnostic criteria: onset is hurried, after companion's facial paralysis is picked up the ears, in ear, mastoid process or facial mild pain, find bicker flowing water when early morning washes one's face and rinses one's mouth, facial exercises is ineffective, distortion of commissure; Or in time taking food, find that food is accumulated in tooth buccal space, side, and saliva is had to drop down from bicker.Sick side surface part histrionic muscles paralysis, catacleisis can not or complete, lacrimal secretion reduces, sick side absent corneal reflex, and nasolabial fold shoals or smooth, ptosis of labial angle, sick side is closed order, is frowned, wrinkle volume, air-blowing, be in a pout, grinningly etc. action all can not.
Therapeutic Method: each raw material of Chinese medicine is pulverized and mixed evenly, crosses 100 mesh sieves, with warm water furnishing pasty state, and drug application Ipsilateral.Changing dressings every day once, 7 days is a course for the treatment of.
Curative effect judging standard:
Cure: clinical symptoms all disappears, catacleisis is good, facial muscle functional rehabilitation;
Effective: clinical symptom relief or partial disappearance, volume stricture of vagina recovers, and upper and lower catacleisis strength is weak, visible Ipsilateral slight ptosis of labial angle when laughing at of crying, and facial muscle groups contractile motion is slightly poor;
Invalid: symptom is without obviously alleviating.
Therapeutic outcome: after the treatment of 1-3 the course for the treatment of, 197 routine patients cure 159 examples, effective 35 examples, invalid 3 examples, cure rate 80.7%, total effective rate 98.5%, and evident in efficacy, cure rate is high, cures follow-up of patients 1-3 and does not recur every year, all do not occur bad side reaction.
Model case 1
Grandson so-and-so, female, 46 years old, acute peripheral facial paralysis, mouth is askew to the right, left eye photophobia, shed tears, left eye can not mis-tie misclosure 1mm, left side plug food, sialorrhea, case history 1 year, right face is larger, face is tight, all has alleviating in various degree by each symptom after 1 course for the treatment of of medicine composite for curing of the present invention, and after the course for the treatment of of continual cure, symptom all disappears, advise it to continue to strengthen a course for the treatment of of treatment, follow up a case by regular visits to and have no recurrence in 2 years.
Model case 2
Turn round and look at certain, man, 57 years old, acute peripheral facial paralysis, left eye can not close, and left eyebrow can not be lifted contour with right eyebrow, and when laughing at, mouth is askew to the right, knows except and heals, follow up a case by regular visits to and do not recur for 2 years with all diseases after 1 course for the treatment of of medicine composite for curing of the present invention.
Model case 3
Summer so-and-so, man, 31 years old, left surface is paralysed completely, face is askew to the right, babble, and face is felt nervous, facial hemiparalysis, face can not be completely closed, is diagnosed as left surface neural paralysis, all has alleviating in various degree by each symptom after 1 course for the treatment of of medicine composite for curing of the present invention, continual cure was fully recovered after the course for the treatment of, followed up a case by regular visits to and did not recur for 1 year.

Claims (2)

1. treat prosopoplegic pharmaceutical composition, it is characterized in that, be made up of the raw material of Chinese medicine of following weight proportioning: Xylocopa dissimilis (Lep.) 5-10g, Folium Cunninghamiae lanceolatae 3-8g, Flos Tagetis Erectae 3-5g, Rhizoma Acori Graminei 5-15g, Herba Seu Radix Peperomiae Tetraphyllae 3-5g, Herba Lysionoti Pauciflori 2-5g, Radix Linderae Glaucae 5-10g, Cissus pteroclada Hayata 3-5g, Radix seu Caulis Parthenocissi tricuspidatae 3-8g, Rhizoma Corydalis Decumbentis 2-5g, Retinervus Luffae Fructus 5-20g, Radix Salviae Miltiorrhizae 5-20g, Ramulus et Folium Actinidiae Polygamae 3-8g, Radix seu Caulis Verntilaginis Leiocarpae 3-5g.
2. the prosopoplegic pharmaceutical composition for the treatment of as claimed in claim 1, is characterized in that, be made up of the raw material of Chinese medicine of following weight proportioning: Xylocopa dissimilis (Lep.) 8g, Folium Cunninghamiae lanceolatae 5g, Flos Tagetis Erectae 5g, Rhizoma Acori Graminei 10g, Herba Seu Radix Peperomiae Tetraphyllae 3g, Herba Lysionoti Pauciflori 3g, Radix Linderae Glaucae 5g, Cissus pteroclada Hayata 5g, Radix seu Caulis Parthenocissi tricuspidatae 5g, Rhizoma Corydalis Decumbentis 4g, Retinervus Luffae Fructus 10g, Radix Salviae Miltiorrhizae 15g, Ramulus et Folium Actinidiae Polygamae 5g, Radix seu Caulis Verntilaginis Leiocarpae 4g.
CN201510039947.8A 2015-01-27 2015-01-27 Pharmaceutical composition for treating facioplegia Pending CN104547352A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168670A (en) * 2015-10-29 2015-12-23 张学英 Chinese medicinal formulae for treating wind pathogen attacking meridian system type facial paralysis

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101658602A (en) * 2009-08-25 2010-03-03 路正平 Drug for treating peripheral facial paralysis
CN103223118A (en) * 2013-03-26 2013-07-31 孙胜波 Traditional Chinese medicine composition for treating facial paralysis
CN103330857A (en) * 2013-07-04 2013-10-02 高新华 Pharmaceutical composition for treating peripheral facial paralysis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101658602A (en) * 2009-08-25 2010-03-03 路正平 Drug for treating peripheral facial paralysis
CN103223118A (en) * 2013-03-26 2013-07-31 孙胜波 Traditional Chinese medicine composition for treating facial paralysis
CN103330857A (en) * 2013-07-04 2013-10-02 高新华 Pharmaceutical composition for treating peripheral facial paralysis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168670A (en) * 2015-10-29 2015-12-23 张学英 Chinese medicinal formulae for treating wind pathogen attacking meridian system type facial paralysis

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