CN103479953A - Method for preparing medicine with function of tonifying spleen to promote digestion - Google Patents

Method for preparing medicine with function of tonifying spleen to promote digestion Download PDF

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CN103479953A
CN103479953A CN201310462741.7A CN201310462741A CN103479953A CN 103479953 A CN103479953 A CN 103479953A CN 201310462741 A CN201310462741 A CN 201310462741A CN 103479953 A CN103479953 A CN 103479953A
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medicine
radix
spleen
semen
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CN103479953B (en
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Wuhan Hong Xintong Science And Technology Ltd
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Abstract

The invention discloses a method for preparing a medicine with a function of tonifying the spleen to promote digestion. The medicine is prepared by the crude drugs in parts by weight as follows: 30 parts of astragali radix, 30 parts of rhizoma dioscoreae, 15 parts of roasted atractylis ovata, 30 parts of semen coicis, 15 parts of honeysuckle,30 parts of dandelion, 15 parts of Chinese angelica, 6 parts of honey-fried licorice roots, 20 parts of dendrobe, 15 parts of eucommia, 10 parts of baical skullcap roots, 15 parts of teasel roots, 15 parts of Indian buead, 10 parts of jade butterfly, 6 parts of liquorice, 10 parts of cassia twigs, 30 parts of hairyvein agrimonia herb and buds, 10 parts of villous amomum, 15 parts of bletilla striata, 15 parts of chrysanthemum, 15 parts of white lablab beans, 10 parts of roasted malts, 15 parts of cortex albiziae and 10 parts of fructus aurantii. The medicine has an unexpected effect on tonifying the spleen to promote digestion.

Description

The preparation method of digestion-promoting spleen-invigorating medicine
Technical field
The present invention relates to technical field of Chinese medicines, be specially a kind of preparation method of digestion-promoting spleen-invigorating medicine.
Background technology
Insufficiency of the spleen dysfunction of the spleen in transportation and transformation, and malnutrition can occur, water liquid loses in spreading and gives birth to the wet expectorant of making, or the disease such as lose blood.Its disease is at stomach, and dyspepsia relates to the internal organs such as liver spleen, and suitable determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, give invigorating the spleen and regulating the stomach, depressed liver-energy dispersing and QI regulating, the treatment of the methods such as dyspepsia and intestinal stasis relieving.But the western medicine side effect is larger, the Chinese patent medicine DeGrain that market is similar.
Summary of the invention
The objective of the invention is, in order to overcome above-mentioned the deficiencies in the prior art part, provides a kind of preparation method of digestion-promoting spleen-invigorating medicine according to Chinese medical theory.
This method:
Get by weight 30 parts of crude drug Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Semen Coiciss, 15 parts of Flos Lonicerae, 30 parts of Herba Taraxacis, 15 parts of Radix Angelicae Sinensis, 6 parts of Radix Glycyrrhizae Preparatas, 20 parts of Herba Dendrobiis, 15 parts of the Cortexs Eucommiae, 10 parts of Radix Scutellariaes, 15 parts of Radix Dipsacis, 15 parts, Poria, 10 parts of Semen Oroxylis, 6 parts, Radix Glycyrrhizae, 10 parts of Ramulus Cinnamomi, 30 parts of Herba Agrimoniaes, 10 parts of Fructus Amomis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Flos Chrysanthemis, 10 parts of Fructus Aurantiis, 10 parts of Fructus Hordei Germinatus (parched)s, 15 parts of Cortex Albiziaes and 15 parts of Semen Lablab Albums standby;
Second step: after the above-mentioned raw materials medicine is mixed, be dried and crushed into fine flour, cross 500 mesh sieves, incapsulate and get final product.
Method provided by the invention, its raw material is Radix Astragali, Rhizoma Dioscoreae, Rhizoma Atractylodis Macrocephalae (parched), Semen Coicis, Flos Lonicerae, Herba Taraxaci, Radix Angelicae Sinensis, Radix Glycyrrhizae Preparata, Herba Dendrobii, the Cortex Eucommiae, Radix Scutellariae, Radix Dipsaci, Poria, Semen Oroxyli, Fructus Hordei Germinatus (parched), Ramulus Cinnamomi, Herba Agrimoniae, Fructus Amomi, the Pseudobulbus Bletillae (Rhizoma Bletillae), Flos Chrysanthemi, Fructus Aurantii, Radix Glycyrrhizae, Cortex Albiziae and Semen Lablab Album, can be used for the vomiting that treatment causes because of insufficiency of the spleen and dyspepsia, abdominal distention and become thin etc., the effect with certain digestion-promoting spleen-invigorating that above-mentioned medical material has, the effect with certain building body had, this formula is in R&D process, the formula of take in the patent of applying on the same day is core, the additional formula drawn by increase and decrease flavour of a drug and adjustment compatibility relationship, insufficiency of the spleen in treatment, dyspepsia, vomiting, abdominal distention and the aspect such as become thin have obtained the curative effect of showing, make this medicine produce beyond thought effect with having no side effect aspect digestion-promoting spleen-invigorating.Through 1 year, observe both without recurring also without obvious toxic and side effects.
The specific embodiment
A kind of preparation method of digestion-promoting spleen-invigorating medicine, by following bulk drugs, made:
Radix Astragali 30g, Rhizoma Dioscoreae 30g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Semen Coicis 30g, Flos Lonicerae 15g, Herba Taraxaci 30g, Radix Angelicae Sinensis 15g, Radix Glycyrrhizae Preparata 6g, Herba Dendrobii 20g, Cortex Eucommiae 15g, Radix Scutellariae 10g, Radix Dipsaci 15g, Poria 15g, Semen Oroxyli 10g, Radix Glycyrrhizae 6g, Ramulus Cinnamomi 10g, Herba Agrimoniae 30g, Fructus Amomi 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Flos Chrysanthemi 15g, Fructus Aurantii 10g, Fructus Hordei Germinatus (parched) 10g, Cortex Albiziae 15g and Semen Lablab Album 10g;
Second step: after the above-mentioned raw materials medicine is mixed, be dried and crushed into fine flour, cross 500 mesh sieves, incapsulate and get final product.Every capsule has above-mentioned raw materials medicine 0.4g.
The drug effect of each crude drug of distinguishing the flavor of is as follows:
1. Radix Astragali: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
2. Rhizoma Dioscoreae: spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.
3. Rhizoma Atractylodis Macrocephalae (parched): invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.
4. Semen Coicis: spleen invigorating, eliminating dampness by diuresis, antidiarrheal, evacuation of pus.
5. Flos Lonicerae: can dispelling wind-heat, also kind removing summer-heat blood poison.
6. Herba Taraxaci: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.
7. Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
8. Radix Glycyrrhizae Preparata: spleen reinforcing stomach function regulating, Yiqi and vein recovery.
9. Herba Dendrobii: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.
10. the Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening, antiabortive.
11. Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.
12. Radix Dipsaci: invigorating the liver and kidney, bone and muscle strengthening, continuous folding wound, only metrorrhagia.
13. Poria: the Poria slightly sweet flavor is flat, enters the heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.
14. Semen Oroxyli: lung moistening, soothing liver-QI, stomach function regulating, granulation promoting.
15. Radix Glycyrrhizae: QI invigorating invigorating middle warmer; Relieving spasm to stop pain; Nourishing the lung to arrest cough; Eliminating fire and detoxication; Coordinating the actions of various ingredients in a prescription.
16. Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation.
17. Herba Agrimoniae: astringing to arrest bleeding, detoxification sore treatment, parasite killing, puckery antiperspirant, cough-relieving.
18. Fructus Amomi: the removing dampness appetizing, warming spleen and stopping diarrha, regulate the flow of vital energy antiabortive.
19. the Pseudobulbus Bletillae (Rhizoma Bletillae): tonifying the lung, relieving cough and resolving phlegm, hemostasia and promoting granulation.
20. Flos Chrysanthemi: loose wind heat clearing away, suppressing the hyperactive liver improving eyesight.
21. Fructus Aurantii: regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.
22. Semen Lablab Album: spleen reinforcing and in, removing dampness is relieved summer heat.
23. Fructus Hordei Germinatus (parched): promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, move back newborn relieving distension.
24. Cortex Albiziae: the resolving depression of calming the nerves is arranged, the effect of the eliminating carbuncle of invigorating blood circulation.
Instructions of taking: the people more than 18 years old three times on the one, each 1.Within 30 days, be a course for the treatment of, take continuously three courses for the treatment of.As taken continuously 1 week symptom without obviously changing or take medicine rear appearance diarrhoea and vomiting increase the weight of, drug withdrawal immediately, transference cure after drug withdrawal.
Clinical trial:
Choose 150 routine functional dyspepsias and with gastrointestinal upset as vomiting, abdominal distention and the Patients of Spleen Deficiency of becoming thin, in age 18-50 year, the course of disease is more than 3 months, in 2 months, do not carry out any treatment.Above-mentioned 150 routine patients are divided into to two groups for the treatment of group and matched groups, treatment group 100 examples, the capsule made with this enforcement is treated, and three times on the oral one, each 1 30 days is a course for the treatment of, takes continuously three courses for the treatment of.Matched group 50 examples, take the domperidone tablet treatment: oral, 10~20m gor suspension 10ml, every day 3~4 times, take 15~30 minutes ante cibum, within 15 days, is a course for the treatment of, takes continuously three courses for the treatment of.Then carry out clinical observation.
Period in a medicine treatment group self clinical observation on the therapeutic effect analysis result is as follows:
The curative effect project The treatment group number of cases Improvement rate (%)
The vomiting number of times reduces 88 88%
Abdominal distention is alleviated 90 90%
Body weight increases 84 84%
Appetite increases 94 94%
Total improvement rate (%) ? 89%
The clinical observation on the therapeutic effect analysis result of period in a medicine treatment group and matched group is as follows:
Figure BDA0000391582230000041
Efficacy assessment standard is as follows:
1, produce effects: vomiting is obviously controlled, and abdominal distention is obviously alleviated, and body weight increases, and appetite increases, the transference cure of all the other gastrointestinal upsets.
2, take a turn for the better: the vomiting number of times reduces or the intermittent time extends, and abdominal distention is alleviated to some extent, and body weight stops alleviating,
Appetite makes moderate progress, and the symptom partial symptoms of all the other gastrointestinal upsets disappears.
3, invalid: symptom is without improving or increasing the weight of.
The comparison sheet of the clinical medicine side effect incidence rate of period in a medicine treatment group and matched group
Figure BDA0000391582230000051
Stomachache and Refuse to take medicine are clinical modal side effect as can be seen from the above table, but can progressively disappear after drug withdrawal.But tremble and the incidence rate of the side effect of having blood in stool, take the matched group of domperidone tablet apparently higher than the treatment group of taking capsule of the present invention, so the present invention does not have obvious toxic and side effects substantially.

Claims (1)

1. the preparation method of a digestion-promoting spleen-invigorating medicine, is characterized in that comprising the steps:
The first step: get by weight 30 parts of crude drug Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Semen Coiciss, 15 parts of Flos Lonicerae, 30 parts of Herba Taraxacis, 15 parts of Radix Angelicae Sinensis, 6 parts of Radix Glycyrrhizae Preparatas, 20 parts of Herba Dendrobiis, 15 parts of the Cortexs Eucommiae, 10 parts of Radix Scutellariaes, 15 parts of Radix Dipsacis, 15 parts, Poria, 10 parts of Semen Oroxylis, 6 parts, Radix Glycyrrhizae, 10 parts of Ramulus Cinnamomi, 30 parts of Herba Agrimoniaes, 10 parts of Fructus Amomis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Flos Chrysanthemis, 10 parts of Fructus Aurantiis, 10 parts of Fructus Hordei Germinatus (parched)s, 15 parts of Cortex Albiziaes and 15 parts of Semen Lablab Albums standby;
Second step: after the above-mentioned raw materials medicine is mixed, be dried and crushed into fine flour, cross 500 mesh sieves, incapsulate and get final product.
CN201310462741.7A 2013-09-30 2013-09-30 The preparation method of digestion-promoting spleen-invigorating medicine Expired - Fee Related CN103479953B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104225375A (en) * 2014-08-25 2014-12-24 江守仲 Traditional Chinese medicine decoction for treating infantile malnutrition

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102772770A (en) * 2012-08-03 2012-11-14 刘元田 Traditional Chinese medicine composition for treating cold-damp affecting spleen syndrome
CN102861298A (en) * 2012-10-18 2013-01-09 林强 Traditional Chinese medicine composition for treating chronic gastritis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102772770A (en) * 2012-08-03 2012-11-14 刘元田 Traditional Chinese medicine composition for treating cold-damp affecting spleen syndrome
CN102861298A (en) * 2012-10-18 2013-01-09 林强 Traditional Chinese medicine composition for treating chronic gastritis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李展: "《基于数据挖掘探讨陈业强教授的脾胃学术思想》", 《中国中西医结合急救杂志》, vol. 20, no. 4, 31 July 2013 (2013-07-31), pages 195 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104225375A (en) * 2014-08-25 2014-12-24 江守仲 Traditional Chinese medicine decoction for treating infantile malnutrition

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Patentee after: Yang Wenwen

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Patentee before: Wuhan Hong Xintong Science and Technology Ltd.

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