CN104544047A - Original orange-flavor buccal tablets prepared from sodium L-ascorbate, and preparation method of buccal tablets - Google Patents

Original orange-flavor buccal tablets prepared from sodium L-ascorbate, and preparation method of buccal tablets Download PDF

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CN104544047A
CN104544047A CN201410764281.8A CN201410764281A CN104544047A CN 104544047 A CN104544047 A CN 104544047A CN 201410764281 A CN201410764281 A CN 201410764281A CN 104544047 A CN104544047 A CN 104544047A
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orange
sodium
vitamine
parts
honey
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CN104544047B (en
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张莘蔓
韦玲菊
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Jiangsu Handian biological Polytron Technologies Inc
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张莘蔓
韦玲菊
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Abstract

The invention discloses original orange-flavor buccal tablets prepared from sodium L-ascorbate, and a preparation method of the buccal tablets. The buccal tablets are prepared from the following raw materials in parts by weight: 500-1500 parts of fresh oranges, 100-300 parts of sodium L-ascorbate, 150-350 parts of isomaltulose, 100-250 parts of Arabic gum, 40-150 parts of honey and 0.5-2 parts of magnesium stearate. The buccal tablets maintain the original taste and flavor of the oranges and enhance the function of the sodium L-ascorbate, thus being a good vitamin supplement and a good health product; the buccal tablets are unique in production technology, good in product molding, simple in technology and easy to operate, and are suitable for industrial production.

Description

A kind of former orange taste vitamine C sodium buccal tablet and preparation technology thereof
Technical field
The invention belongs to field of health care food, relate to a kind of former orange taste vitamine C sodium buccal tablet and preparation technology thereof.
Background technology
Vitamin C is also known as ascorbic acid, it is a kind of water soluble vitamin, there is the function of ascorbic acid disease, maintain the indispensable material of human normal physiological metabolism, there is important physiological function, amino acid and neurotransmission is participated in human body, the synthesis of collagen, it participates in hydroxylation reaction in body, for forming bone, tooth, between connective tissue and non-Epithelial cell, sticky thing institute is required, tooth can be maintained, bone, the normal function of blood vessel, increase the resistivity to disease, it also has the permeability reducing capillary, the function stimulating blood coagulation and the resistant function etc. increased infecting.In all kinds of crowd, have shortage in various degree according to interrelated data report vitamin C, when some indispositions appear in health, just should supplement appropriate vitamin in time and mineral matter improves deficiency disease, especially person in middle and old age should comparatively pay attention to.Vitamin C has prevention effect to numerous disease, the people that in body, vitamin C is high, absorbs the harmful elements such as lead, cadmium, chromium more hardly the people of contaminated environment work; More the people smoked eats and helps containing ascorbic food the resistance improving cell, keeps the elasticity of blood vessel, eliminates the nicotine in body; Be engaged in the people of strenuous exercise and highly intensive labour, these people, because of too much meeting large losses vitamin C of sweating, should be supplemented in time; Vitamin C Wheat Protein, replenishing vitamins C can suppress the generation of pigmented spots, promotes that it disappears; Aspirin, hypnotic, anticancer change medicine, tetracycline, calcium product, contraceptive, depressor etc., all can make body vitamin C reduce, and can cause other bad reaction, should replenishing vitamins C in time.
Vitamin C is clinical basic common drug, be widely used on various diseases prevention and therapy, because vitamin C aqueous ph value is close to about 2, therefore, acidity is comparatively large, orally uses oral cavity, throat esophagus and gastric stimulation comparatively large, unsuitable long-term taking, also be not suitable for taking with acidic drug simultaneously, use is subject to a definite limitation.And vitamine C sodium is ascorbic sodium salt, aqueous ph value is close to neutral, and its effect is identical with ascorbic acid, but owing to being sodium salt, so performance is more stable, no longer include ascorbic highly acid simultaneously, can for a long time and multi-medicament take simultaneously, be more better than vitamin C.Vitamine C sodium belongs to domestic and international widely used vitamin C intensified dose, progressively substitutes vitamin C and uses.
Orange is the fruit of Rutaceae citrus plant orange tree, and fruit peeling can eat its pulp raw, and pulp also can be used as the additives of other foods.Its fruit juice taste is sweet and fragrant, and containing a large amount of sugar and a certain amount of citric acid and abundant vitamin C, nutritive value is higher, fruit also containing citrin, the pharmaceutical value that tool is high.Analyze according to nutritionist, the biotic energy index of orange is 13.8750, and disease prevention index is 132.50.Orange is rich in the active principles such as hesperidine, citric acid, malic acid, butanedioic acid, carbohydrate, pectin and vitamin, nature and flavor acid, cool.Australian Union's science and industrial research tissue find, it can prevent oral cavity, the cancer of esophagus and stomach occurs; It can also make the incidence of apoplexy reduce by 19%, and orange is counted as ascorbic main source of supply in the middle of Western diet traditionally, also can provide the mineral matter such as a considerable amount of carrotene and potassium, calcium, iron.According to another U.S.'s research institution's research display, orange juice can increase the content of HDL in body (HDL), thus reduce the possibility suffered from a heart complaint, because the vitamin C in orange can suppress cholesterol to be converted into bile acid in liver, thus the concentration of bile cholesterol is declined, both assemble the chance also just corresponding minimizing forming gall stone; Dermal melanin calmness can be made to reduce, thus reduce blackspot and freckle, make whitening skin; Contribute to recovering skin elasticity, prevent anaphylactoid generation; The formation of carcinogen can be suppressed, can also soften and protect.In addition, pectin contained in orange peel also can promote that food passes through intestines and stomach, cholesterol is excreted with ight soil quickly, to reduce the absorption of cholesterol, can promote that HDL increases, and the low-density lipoprotein (LDL) transporting " bad " is to external, blood vessel, stimulate circulation, reduce cholesterol and blood fat.Will have a greatly reduced quality iff its health-care effect of extracting orange juice, because in processing orange juice process, the loss of vitamin C, Flavonoid substances and carotenoid is a lot, and other dietary fibers beyond pectin are almost with regard to total loss.
Honey, main component is fructose (molecular formula is C6H12O6), water, and also having trace element and the inorganic salts such as a small amount of copper iron calcium, is the highly finished product of the glucide that honeybee is led in honeycomb, and nature and flavor are sweet, flat, enter lung, spleen, large intestine channel.Have hypotensive, protect the effect such as liver, alleviating pain honey and be not only delicious nutriment, and be treatment various diseases, strong health and the medicine of promoting longevity.Honey is useful especially with the children being easy to the food digested for somagenic need high heat, and it can promote appetite, improves metabolism, people's spirit is good for refreshing and full of physical strength, improves body to the resistance of disease.
Isomaltoketose, because the secretion of insulin can not be caused after its digested absorption, also the activation of LPL activity would not be caused, so the existence of isomaltoketose makes grease be not easy to be absorbed in adipose tissue, isomaltoketose can also improve mental concentration and to releive nervous effect, it can not be caused the microorganism of decayed tooth to utilize by oral cavity, certainly also insoluble polydextrose would not be produced, isomaltoketose not only itself can not cause decayed tooth, more has the decayed tooth effect suppressing to be caused by sucrose.
At present, domestic and international market also has sodium vitamin C formulation to go on the market, mainly the formulation such as capsule, masticatory, lozenge, of less types, and be substantially all add the additive such as essence, pigment, be not suitable for long-term taking, and its composition is more single, and health care is poor.Now be badly in need of a kind of instant of exploitation, be of high nutritive value, easily store and take, and can long-term taking product.Finding by retrieving domestic and international prior art, also not preparing the report of former orange taste vitamine C sodium buccal tablet with orange and vitamine C sodium, honey, isomaltoketose for major ingredient at present.Based on above theoretical and Shortcomings, this patent develops former orange taste vitamine C sodium buccal tablet on the basis solving many technical problems, is of high nutritive value, pure in mouth feel, safe without toxic side effect, and processing technology is relatively simple, produces than being easier to realize industrialization.
Summary of the invention
Content of the present invention is to provide a kind of former orange taste vitamine C sodium buccal tablet of effective, taking convenience, pure taste, and prepares the preparation method of this buccal tablet.This product have ascorbic acid disease, anti-oxidant, antitumor, reduce lipid peroxidation, improve the effects such as immunity of organisms, cough-relieving wet one's whistle, can be used for prevention and supplemental treatment scurvy and various acute and chronic communicate illness or other diseases to strengthen Abwehrkraft des Koepers, after being ill convalescence During Wound Healing and the health therapy of anaphylactia.
The former orange taste vitamine C sodium buccal tablet of the present invention adopts orange fresh goods to squeeze Normal juice, and pomace pulverizes achievement powder after adding isomaltoketose vacuum drying, and it retains the distinctive color of orange and smell, without the need to adding pigment and essence again.Adopt orange juice repeatedly to granulate after orange fruit powder adds honey, Arabic gum, particle adds vitamine C sodium compressing tablet, makes former orange taste vitamine C sodium buccal tablet, the present invention improves product original flavor, mouthfeel and health care, it can make lozenge forming, and outward appearance is beautiful, and mouthfeel is good.
The present invention overcomes correlation technique difficult point by screening science prescription composition and unique preparation technology, by product prepared by this method, both the active ingredient of former orange, local flavor and color and luster had been kept, and improve product medicine and health care value, and vitamine C sodium pH value is close to neutral, it can alleviate acid stimulation, is easy to product and sucks.In prescription of the present invention, primary raw material vitamine C sodium has stronger clinical function, it can be used for a variety of causes and causes vitamin C deficiency to prevent, and also can be used for the treatment of hypovitaminosis C clinical disease, simultaneously because its PH is close to neutral, select it to make buccal tablet mouthfeel better, excitant is less.Granulate owing to directly adopting the sub-Normal juice of orange, it increases the active principle content such as vitamin C, and containing orange primary colors and peculiar fragrance, therefore, without the need to adding pigment and essence in prescription, retain color and luster and the local flavor of former orange greatly, embody the original taste of orange and the smell of product, strengthen Product Safety.Preparation technology of the present invention is easy simultaneously, be applicable to suitability for industrialized production, and product taking convenience safety, effect is good again, genuine, is applicable to all kinds of crowd's long-term taking.
Technical solution of the present invention is:
A kind of former orange taste vitamine C sodium buccal tablet, raw material is made up of the component of following weight portion: the sub-500-1500 part of orange, vitamine C sodium 100-300 part, isomaltoketose 150-350 part, Arabic gum 100-250 part, honey 40-150 part, dolomol 0.5-2 part.
The above former orange taste vitamine C sodium buccal tablet, raw material is preferably made up of the component of following weight portion: the sub-800-1200 part of orange, vitamine C sodium 150-250 part, isomaltoketose 200-300 part, Arabic gum 150-200 part, honey 70-120 part, dolomol 1-1.5 part.
The above former orange taste vitamine C sodium buccal tablet, raw material the best is preferably made up of the component of following weight portion: orange 1000 parts, vitamine C sodium 200 parts, isomaltoketose 150 parts, Arabic gum 175 parts, honey 95 parts, dolomol 1.0 parts.
The preparation method of the above former orange taste vitamine C sodium buccal tablet, comprises the following steps:
1. take raw material by following weight portion: the sub-500-1500 part of orange, vitamine C sodium 100-300 part, isomaltoketose 150-350 part, Arabic gum 100-250 part, honey 40-150 part, dolomol 0.5-2 part.
2. get orange, clean, remove the peel, remove seed, put in juice extractor and squeeze Normal juice, fruit juice centrifuge or 200-300 mesh filter screen divide gets normal juice, for subsequent use;
3. get above-mentioned orange pomace, add isomaltoketose, mix, be dried to moisture content 3-10%, be ground into compound pomace fine powder, cross 200-300 mesh sieve, obtain compound orange powder;
4. get above-mentioned compound orange powder, add Arabic gum, mix, then add the orange normal juice that honey and step 2 obtain, softwood processed, granulates, and dry, whole grain, particle adds vitamine C sodium, dolomol, mixes, and compressing tablet to obtain final product.
The preparation method of the above former orange taste vitamine C sodium buccal tablet, the granulation step in described step 4 preferably adopts multi granulating method: pulverize after making particle drying for the first time, then adopts orange normal juice multi granulating; And particle drying adopts vacuum drying method, and baking temperature is 40 DEG C-60 DEG C.
The preparation method of the above former orange taste vitamine C sodium buccal tablet, the orange normal juice obtained in step 2 first can be condensed into appropriate concentrate by the granulation step in described step 4, for granulating.
The preparation method of the above former orange taste vitamine C sodium buccal tablet, described step 3 drying steps preferably adopts vacuum drying method, and baking temperature is 40 DEG C-60 DEG C.
In technique of the present invention, orange to be squeezed the juice technology, it can retain the distinctive active ingredient of orange, fragrance and color and luster, and pomace add isomaltoketose drying after adopt micronizer to pulverize, and add honey softwood, the products taste of preparation is fine and smooth, fresh and sweet, more embodies the genuineness of product.Production technology of the present invention is unique, and formed product is good, and technique is simple, easy to operate, can be applicable to suitability for industrialized production.
According to the scientific and reasonable screening auxiliary material of the characteristic of vitamine C sodium and proportioning in the present invention's formula, in order to solve the difficult problem such as preparations shaping and products taste, in preparations shaping, select Arabic gum and honey as combination adhesive, they not only have stronger adhesion strength and soft elasticity, make product color good, outward appearance is beautiful, also has and strengthens product trophic function.Arabic gum is a kind of natural plants hydrosol, and it does not produce heat substantially, is good water-soluble dietary fiber, and medically Arabic gum also has the function reducing Blood Cholesterol; And in order to the mouthfeel of improving product and outward appearance, keep product lubricity and orange fragrance, adopt the honey with good performance of keeping humidity, the moisture that it can make product keep certain, prevent drying, and due to it be nonvolatile polyalcohol, keep the special aromatic function of product so also have, strengthen mouthfeel and the aroma effect of product.Meanwhile, in order to improve, orange is acid and sweet taste inadequate, adopts to add appropriate isomaltoketose sweetener and strengthen mouthfeel and promote the effect of promoting the production of body fluid in this prescription, is conducive to diabetic to take, raising product function.
In order to reach above-mentioned effect, inventor has done a large amount of experiments, and part research conditions is as follows:
One, adhesive screening
In order to solve preparations shaping problem, the adhesives such as dextrin, sodium carboxymethylcellulose, gelatin, slurry glucose, polyvinylpyrrolidone are tried out, but because mouthfeel or granulation and molding effect bad and abandon, finally determine in preparations shaping, to select Arabic gum and honey as combination adhesive, in table 1.
Table 1 adhesive the selection result table (unit: g)
The above results shows, formula 1,7 weak effects, can not be for the production of, and formula 2-6 molding effect is better, and can be used for large production, 4 effects of wherein filling a prescription are best, and mouthfeel is good.
Two, sweetener screening
Sucrose, stevioside, saccharin sodium, xylitol, maltitol etc. have been tried out, in table 2 in test.
Table 2 sweetener the selection result table (unit: g)
Remarks: "+" is more, effect is better.
Above-mentioned result of the test shows, selects isomaltoketose to do sweetener mouthfeel best, gentle fine and smooth.And having certain adhesive effect, hygroscopicity is very low, is beneficial to storage.
In a word, the present invention, by lot of experiments, is preferably applicable to the characteristic supplementary material composition of vitamine C sodium, and prescription composition science, technique is unique, and without the need to adding the industrial chemicals such as pigment, essence, product safety performance is high.By the lozenge that this prescription makes, mouthfeel is good, taking convenience, and retaining orange genuineness and enhance vitamine C sodium function, is a kind of good vitamin replenisher and health products.Meanwhile, easy, the science of prescription composition of the present invention, product bioavilability is high, effective, is applicable to all kinds of crowd's long-term taking.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described, but do not limit the scope of the invention and range of application:
One, the preparation method of former orange taste vitamine C sodium buccal tablet
Embodiment 1
A preparation method for former orange taste vitamine C sodium buccal tablet, comprises the following steps:
1. take raw material by following weight portion: the sub-50kg of orange, vitamine C sodium 10kg, isomaltoketose 15kg, Arabic gum 10kg, honey 4kg, dolomol 0.05kg.
2. get orange, clean, remove the peel, remove seed, put in juice extractor and squeeze Normal juice, fruit juice centrifuge divides gets normal juice, for subsequent use;
3. get above-mentioned orange pomace, add isomaltoketose, mix, adopt boulton process 80 DEG C to be dried to moisture content 3%, pulverize with the impact grinding of high energy nanometer, cross 200 mesh sieves, powder not by sieve is pulverized again, after 200 mesh sieves, the superfine powder after sieving is mixed, obtains compound orange powder;
4. get above-mentioned compound orange powder, add Arabic gum, mix, then add the orange normal juice that honey and step 2 obtain, mix softwood processed, granulate, particle 80 DEG C of vacuum drying, whole grain, particle adds vitamine C sodium, dolomol, mixes, and compressing tablet to obtain final product.
Embodiment 2
A preparation method for former orange taste vitamine C sodium buccal tablet, comprises the following steps:
1. take raw material by following weight portion: the sub-80kg of orange, vitamine C sodium 15kg, isomaltoketose 20kg, Arabic gum 15kg, honey 7kg, dolomol 0.1kg.
2. get orange, clean, remove the peel, remove seed, put in juice extractor and squeeze Normal juice, fruit juice divides with 300 mesh filter screens gets normal juice, for subsequent use;
3. get above-mentioned orange pomace, add isomaltoketose, mix, adopt boulton process 40 DEG C to be dried to moisture content 10%, pulverize with the impact grinding of high energy nanometer, cross 300 mesh sieves, powder not by sieve is pulverized again, after 300 mesh sieves, the superfine powder after sieving is mixed, obtains compound orange powder;
4. get above-mentioned compound orange powder, add Arabic gum, mix, then add the orange normal juice that honey and step 2 obtain, mix softwood processed, granulate, particle 40 DEG C of vacuum drying, whole grain, particle adds vitamine C sodium, dolomol, mixes, and compressing tablet to obtain final product.
Embodiment 3
A preparation method for former orange taste vitamine C sodium buccal tablet, comprises the following steps:
1. take raw material by following weight portion: the sub-120kg of orange, vitamine C sodium 25kg, isomaltoketose 30kg, Arabic gum 20kg, honey 12kg, dolomol 0.15kg.
2. get orange, clean, remove the peel, remove seed, put in juice extractor and squeeze Normal juice, fruit juice divides with 300 mesh filter screens gets normal juice, for subsequent use;
3. get above-mentioned orange pomace, add isomaltoketose, mix, adopt boulton process 60 DEG C to be dried to moisture content 5%, pulverize with the impact grinding of high energy nanometer, cross 300 mesh sieves, powder not by sieve is pulverized again, after 300 mesh sieves, the superfine powder after sieving is mixed, obtains compound orange powder;
4. get above-mentioned compound orange powder, add Arabic gum, mix, add the orange normal juice that honey and step 2 obtain again, mix softwood processed, granulate, particle, 60 DEG C of vacuum drying, is pulverized after making particle drying for the first time, then adopts remaining orange normal juice to granulate, until orange normal juice is finished, whole grain, particle adds vitamine C sodium, dolomol, mixes, compressing tablet, to obtain final product.
Embodiment 4
A preparation method for former orange taste vitamine C sodium buccal tablet, comprises the following steps:
1. take raw material by following weight portion: the sub-150kg of orange, vitamine C sodium 30kg, isomaltoketose 35kg, Arabic gum 25kg, honey 15kg, dolomol 0.20kg.
2. get orange, clean, remove the peel, remove seed, put in juice extractor and squeeze Normal juice, fruit juice divides with 300 mesh filter screens gets normal juice, and 60 DEG C of reduced pressure concentrations become appropriate concentrate, for subsequent use;
3. get above-mentioned orange pomace, add isomaltoketose, mix, adopt boulton process 60 DEG C to be dried to moisture content 8%, pulverize with the impact grinding of high energy nanometer, cross 300 mesh sieves, powder not by sieve is pulverized again, after 300 mesh sieves, the superfine powder after sieving is mixed, obtains compound orange powder;
4. get above-mentioned compound orange powder, add Arabic gum, mix, then add the orange concentrate that honey and step 2 obtain, mix softwood processed, granulate, particle 60 DEG C of vacuum drying, whole grain, particle adds vitamine C sodium, dolomol, mixes, and compressing tablet to obtain final product.
Embodiment 5
A preparation method for former orange taste vitamine C sodium buccal tablet, comprises the following steps:
1. take raw material by following weight portion: the sub-100kg of orange, vitamine C sodium 20kg, isomaltoketose 15kg, Arabic gum 17.5kg, honey 9.5kg, dolomol 0.15kg.
2. get orange, clean, remove the peel, remove seed, put in juice extractor and squeeze Normal juice, fruit juice divides with 300 mesh filter screens gets normal juice, for subsequent use;
3. get above-mentioned orange pomace, add isomaltoketose, mix, adopt boulton process 50 DEG C to be dried to moisture content 6%, pulverize with the impact grinding of high energy nanometer, cross 300 mesh sieves, powder not by sieve is pulverized again, after 300 mesh sieves, the superfine powder after sieving is mixed, obtains compound orange powder;
4. get above-mentioned compound orange powder, add Arabic gum, mix, add the orange normal juice that honey and step 2 obtain again, mix softwood processed, granulate, particle, 50 DEG C of vacuum drying, is pulverized after making particle drying for the first time, then adopts remaining orange normal juice to granulate, until orange normal juice is finished, whole grain, particle adds vitamine C sodium, dolomol, mixes, compressing tablet, to obtain final product.
Two, subjective appreciation
By above-mentioned 5 the embodiment samples prepared, allow 50 people foretaste respectively, carry out sense organ investigation evaluation.Evaluation project has: lozenge structural state, color and luster, local flavor, mouthfeel, and recycling weighting method calculates total score, and structural state weight coefficient is 0.2, and color and luster weight coefficient is 0.2, and local flavor weight coefficient is 0.3, mouthfeel weight coefficient, and 0.3, the results are shown in Table 3.
Table 3 buccal tablet results of sensory evaluation table
Above-mentioned result of the test shows, 5 embodiment samples that the present invention prepares, and subjective appreciation is effective, and weight score is more than 7 points.Illustrate that the present invention can retain the distinctive active ingredient of orange, fragrance and color and luster, and pomace add isomaltoketose drying after adopt micronizer to pulverize, and add honey softwood, the products taste of preparation is fine and smooth, fresh and sweet, retaining orange genuineness and enhance vitamine C sodium function, is a kind of good vitamin replenisher and health products; Adopt orange normal juice multi granulating, and particle drying adopts vacuum drying method, the buccal tablet fragrance obtained is stronger, and rate of drying is also very fast.Production technology of the present invention is unique, and formed product is good, and technique is simple, easy to operate, can be applicable to suitability for industrialized production.

Claims (6)

1. a former orange taste vitamine C sodium buccal tablet, it is characterized in that, raw material is made up of the component of following weight portion: the sub-500-1500 part of orange, vitamine C sodium 100-300 part, isomaltoketose 150-350 part, Arabic gum 100-250 part, honey 40-150 part, dolomol 0.5-2 part.
2. former orange taste vitamine C sodium buccal tablet according to claim 1, it is characterized in that, raw material is made up of the component of following weight portion: the sub-800-1200 part of orange, vitamine C sodium 150-250 part, isomaltoketose 200-300 part, Arabic gum 150-200 part, honey 70-120 part, dolomol 1-1.5 part.
3. former orange taste vitamine C sodium buccal tablet according to claim 1, it is characterized in that, raw material is made up of the component of following weight portion: orange 1000 parts, vitamine C sodium 200 parts, isomaltoketose 150 parts, Arabic gum 175 parts, honey 95 parts, dolomol 1.0 parts.
4. a preparation method for former orange taste vitamine C sodium buccal tablet as claimed in claim 1, is characterized in that, comprise the following steps:
(1) raw material is taken by following weight portion: the sub-500-1500 part of orange, vitamine C sodium 100-300 part, isomaltoketose 150-350 part, Arabic gum 100-250 part, honey 40-150 part, dolomol 0.5-2 part.
(2) get orange, clean, remove the peel, remove seed, put in juice extractor and squeeze Normal juice, fruit juice centrifuge or 200-300 mesh filter screen divide gets normal juice, for subsequent use;
(3) get above-mentioned orange pomace, add isomaltoketose, mix, be dried to moisture content 3-10%, be ground into compound pomace fine powder, cross 200-300 mesh sieve, obtain compound orange powder;
(4) get above-mentioned compound orange powder, add Arabic gum, mix, then add the orange normal juice that honey and step (2) obtain, softwood processed, granulates, dry, whole grain, particle adds vitamine C sodium, dolomol, mixes, and compressing tablet to obtain final product.
5. the preparation method of former orange taste vitamine C sodium buccal tablet according to claim 4, it is characterized in that, granulation step in described step (4) adopts multi granulating method: pulverize after making particle drying for the first time, then adopt orange normal juice multi granulating; And particle drying adopts vacuum drying method, and baking temperature is 40 DEG C-60 DEG C.
6. the preparation method of former orange taste vitamine C sodium buccal tablet according to claim 4, is characterized in that, described step (3) drying steps adopts vacuum drying method, and baking temperature is 40 DEG C-60 DEG C.
CN201410764281.8A 2014-12-11 2014-12-11 A kind of former orange taste sodium ascorbate buccal tablet and preparation technology thereof Expired - Fee Related CN104544047B (en)

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CN107496645A (en) * 2017-08-11 2017-12-22 防城港圣保堂制药有限公司 A kind of ion Vc composition containing Chinese yam and preparation method thereof
CN108175104A (en) * 2018-01-18 2018-06-19 广东健林生物科技有限公司 A kind of homovitamin C content chewable tablets and preparation method thereof

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