CN104524509B - 一种治疗婚久继发不孕的中药组合物 - Google Patents
一种治疗婚久继发不孕的中药组合物 Download PDFInfo
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Abstract
本发明公开了一种治疗婚久继发不孕的中药组合物,其特征在于由艾叶10‑15份,制香附10‑15份,干姜10‑15份,制附子6‑9份,肉桂4‑6份,仙灵脾10‑15份,当归10‑15份,熟地12‑20份,川芎6‑12份,炒白芍10‑15份,紫石英20‑30份,桃仁8‑12份,红花6‑12份,杜仲10‑15份,党参8‑12份,益母草20‑30份,泽兰10‑15份,路路通8‑12份,川牛膝8‑12份,菟丝子10‑15份,神曲15‑20份,桂枝6‑8份,炒白术10‑15份,王不留行10‑15份,巴戟天10‑15份,炙甘草5‑8份,水适量制成。本发明原料来源丰富,成本低廉,制作方法简便易行,使用安全简便,无任何副作用,用于治疗婚久继发不孕疗效明显。
Description
技术领域:
本发明涉及一种中药组方,更确切地说涉及一种治疗多种病因所致的女性婚久不孕的中药组合物。
背景技术:
女性婚久继发不孕是多种病因导致的结果,如宫寒,子宫幼小,多囊卵巢,输卵管不通畅,卵泡发育不良或排卵缓慢等。现有的西药疗效低,副作用大且价格昂贵;手术疗法疗效好,但费用较高。
发明内容:
本发明的目的在于克服现有技术的不足,提供一种治疗多种病因所致婚久继发不孕的中药组合物,原料来源方便,制作加工简便。
本发明所述的中药组合物又名暖宫通孕汤剂,其特征在于按重量计,由下述组分制成:艾叶10-15份,制香附10-15份,干姜10-15份,制附子6-9份,肉桂4-6份,仙灵脾10-15份,当归10-15份,熟地12-20份,川芎6-12份,炒白芍10-15份,紫石英20-30份,桃仁8-12份,红花6-12份,杜仲10-15份,党参8-12份,益母草20-30份,泽兰10-15份,路路通8-12份,川牛膝8-12份,菟丝子10-15份,神曲15-20份,桂枝6-8份,炒白术10-15份,王不留行10-15份,巴戟天10-15份,炙甘草5-8份,水适量。
在一个具体实施例中,按重量计,由下述组分制成:
艾叶12份、制香附12份、干姜12份、制附子8份、肉桂5份、仙灵脾12份、当归12份、熟地15份、川芎10份、炒白芍12份、紫石英25份、桃仁10份、红花10份、杜仲12份、党参10份、益母草20份、泽兰12份、路路通10份、川牛膝10份、菟丝子15份、神曲18份、桂枝7份、炒白术12份、王不留行12份、巴戟天12份、炙甘草6克,水适量。
各种药物的机理:
艾叶:辛温、归脾、肾经。温经止血、散瘀止痛、温固冲任、治月经不调、痛经、心腹疼痛、温肾促孕。
制香附:辛、微苦、平,归肝、三焦经。疏肝理气、调经止痛、月经不调、乳房胀痛、胃疼消化不良等。
干姜:辛、热,归肺、脾、胃经。温中回阳、温肺化饮。治心腹冷痛、呕吐腹泻、肢冷脉微、寒饮咳喘、风寒湿脾、寒性出血等。
制附子:辛、热,有毒,归心、肾、脾经。回阳救逆、补火助阳、散寒止痛。治阳虚厥脱、四肢厥冷,畏寒自汗,脾虚久泻、久痢、脘腹冷痛,脚气水肿,风寒湿痹,肾虚阳痿,阴寒凝滞,一切沉寒痼冷之疾等。
肉桂:辛、甘、热,归肝、心、肾、脾经。补火助阳、散寒止痛、温通经脉。治命门火衰、肢冷脉微、腹痛泄泻、寒疝奔豚、腰膝冷痛,中寒恶食。经闭症瘕,阴疽流注,小便不利,虚阳上浮,上热下寒等。
仙灵脾:辛、温、甘,归肝、肾经。补肾壮阳,祛风除湿、治阳痿不举、小便淋漓不尽,不育不孕,筋骨挛急,有促进精液卵子分泌,扩张周围血液助孕等。
当归:甘、辛、温,归肝、心、脾经。补血,活血,止痛,滑肠。治血虚,月经不调,痛经,闭经,崩漏,风湿痹痛,跌打损伤,痛疽疮疡,症瘕积聚,血虚便闭,脱发等。
熟地:甘、微温,归肝、肾经。养血滋阴、补精益髓。治血虚面色黄、眩晕、心悸、怔忡、失眠、月经不调、崩漏、胎动不安、肝肾阴虚、潮热盗汗、遗精、气喘、消渴腰膝酸软。有强心利尿、降血糖作用。
川芎:辛温、归肝、胆经,心包经。活血行气,祛风止痛,治血瘀气滞所致胸胁及脘腹疼痛,闭经痛经,难产,产后瘀血腹痛,月经不调,半身不遂,外感头痛,风湿痹痛等。
白芍:苦酸、凉、归肝、脾经。养血柔肝,暖中止痛,敛阴止汗,平肝潜阳。治血虚月经不调,胸腹胁肋疼痛,泻痢腹痛,自汗盗汗肝阳眩晕等。
紫石英:甘、温、归心、肾、肝经。镇心安神,降逆暖宫,宫寒不孕等。亦治虚劳惊悸、怔忡、抽搐痉挛,咳逆上气。
桃仁:苦、平、归肝肺、大肠经。活血祛瘀,润肠通便,治血滞经闭,症瘕、热病蓄血、跌打损伤,风痹疼痛,血燥便秘,咳喘痈肿疮毒等。还有抗劳,兴奋子宫作用。
红花:辛、温、归肝、心经。活血散瘀、通经。治闭经、症瘕、痛经、难产、产后血晕、口噤、胎死腹中,产后恶露不净,瘀血心痛,跌打损伤、痈肿等。还有兴奋子宫作用。
杜仲:甘、温、归肝、肾经。补肝肾,健筋骨、安胎。治肝肾亏损,腰脊酸痛,足膝痿弱,小便余沥,阴下湿痒,头晕目眩,胎动不安,胎漏等。
党参:甘、平,归脾、肺经。补中益气,生津养血。治肺脾两虚,食少便溏,四肢乏力,心悸气短、口干、自汗,咳嗽、脱肛,子宫脱垂,血虚萎黄。降低血压,升高血糖,收缩子宫,促进血液凝固,对神经系统兴奋,提高机体抵抗力。有祛痰健胃,加强新陈代谢作用。
益母草:辛、苦、凉、归肝心、膀胱经。活血祛瘀、利水消肿。治月经不调、闭经、产后血晕、瘀阻腹痛、恶露不尽、胎衣不下,跌打瘀痛,水肿、小便不利,痈肿疮毒。还有兴奋子宫、利尿降压,兴奋呼吸中枢作用。
泽兰:苦、辛、微温,归肝、脾经。活血祛瘀,行水消肿。治月经不调,经闭症瘕,产后瘀血腹痛,金疮、痈肿、跌打损伤水肿,小便不利。有强心活血,止痛作用。
路路通:辛、苦、平、归肝、胃、膀胱经。祛风通络,利水除湿。治肢体痹痛,手足拘挛,胃痛,水肿、胀满经闭、乳少、痈疽、痔漏、疥癣、湿疹等。
川牛膝:甘、微苦、平,归肝、肾、膀胱经。活血祛瘀,补肝肾强筋骨,利水通淋,引血下行。治瘀血闭经,症瘕、难产、胎衣不下,风湿痹痛,跌打损伤,腰膝痿软,阴虚火旺之咽喉肿痛,眩晕头痛,吐血、衄血、小便不利,尿淋涩痛。
菟丝子:辛、甘、平归肝、肾经。补阳益阴,固精缩尿,明目止泻。治肾亏阳痿、遗精、尿频、胎动不安,可使子宫收缩等。
神曲:甘、辛、温,归脾、胃经。消食和胃,治饮食积滞,食不消化、脘腹胀满,嗳气泛酸、泻痢、小儿消化不良。
白术:苦、甘、温,归脾、胃经。补气健脾,燥湿利水,止汗安胎。治脾胃气虚,不思饮食,倦怠少气,虚胀泄泻,痰饮水肿,小便不利,黄疸、湿痹、自汗、头晕、胎气不安等。
桂枝:辛、甘、温,归心、肺、膀胱经。发汗解表,温经通阳,治外感风寒,头痛身疼,有汗或无汗,痰饮咳喘,风湿痹痛,跌打损伤,瘀血作痛,经闭腹痛症瘕等。
王不留行:苦、平,归肝、胃经。活血通经,下乳,治妇女血瘀经闭、痛经,乳汁不通,乳房结块,乳痈,小便不利,淋证痈肿,金疮出血等。还能使子宫收缩。
巴戟天:辛、甘、微温,归肾经。补肾助阳祛风除湿。治阳痿早泄,少腹冷痛,腰膝酸软,小便失禁,子宫虚冷,风寒湿痹等。
炙甘草:甘、平、蜜炙变温,归心肺、脾、胃经。补益脾气,润肺止咳,缓急止痛,缓和药性。治脾胃虚弱,食少、自汗,脉结代,腹胀便溏,劳倦发热,肺痿咳嗽,心悸,药物及食物中毒,调和诸药等。
辨证论治:
肾为生胎之元,肾虚则胎孕难成,故治疗女性不孕,从肾入手,《内经》云“冲为血海”“太冲脉盛月事以时下,故有子”说明肾气冲盛是卵巢功能正常的基础,肾与排卵功能及受孕有直接关系。阳虚阴寒之女性,最易形成多囊卵巢及宫寒不孕。阳虚寒凝不孕为本虚标实之证,其本为阳虚,标为阴寒凝滞,经脉不通,故治宜扶阳抑阴,温经通脉。凡属寒邪凝滞,血脉而有寒冷疼痛,月经退后,色淡红质稀,腰膝酸软,怕冷,四肢不温,下腹凉,经来腹痛,肢体虚胖,疲乏无力,面色苍白或晦暗,性欲淡漠,小便清长,夜尿多,大便溏,舌淡嫩,苔白润,脉沉迟或沉细无力,尺脉尤弱。或输卵管不通,盆腔有积液不孕等,上方具有温肾阳补气血,通血脉,促排卵,摄精助孕之作用。
方中:制附子、干姜、肉桂、艾叶温散里寒,温肾暖宫,当归、白芍、熟地、川芎、党参、炙甘草,大补气血而生精;紫石英、巴戟天用以温补肝肾,仙灵脾补肾壮阳;路路通、王不留行、疏通输卵管而利水,据有关资料报道,附子、熟地二药相配,具有促进排卵的作用。通过临床观察,发明人认为补肾药尚有促进内生殖器血液循环的作用。通过丰富血液供应,提高卵巢,子宫的代谢,从而促进卵巢子宫的生长发育,由此可使经脉调和而受孕。
制作方法:
把艾叶、制香附、干姜、制附子、肉桂、仙灵脾、当归、熟地、川芎、炒白芍、紫石英、桃仁、红花、杜仲、党参、益母草、泽兰、路路通、川牛膝、菟丝子、神曲、桂枝、炒白术、王不留行、巴戟天、炙甘草二十六味中药放入砂锅内加水超过药二公分,浸泡三十分钟;上炉煎煮,先武火,煮开后再放入薄荷,继续文火煎至20-30分钟,滤出药汁,再加水煎二次滤汁,合并滤液。
使用方法:每日一剂,得500ml左右药液,分早晚二次分服,每次口服250毫升。十五日为一疗程。
注意事项:服药期间忌生冷凉食,忌喝绿豆稀饭。
有益效果:由上述技术方案可知,本发明原料来源丰富,成本低廉,制作方法简便易行,使用安全简便,无任何副作用,用于治疗多种病因导致的婚久继发不孕症疗效明显。
临床资料:门诊共治疗92例女性婚久继发性不孕患者,年龄最大42岁,最小20岁。其中宫寒伴多囊卵巢,输卵管欠通者24例;宫寒伴输卵管囊肿者56例;宫寒伴子宫小肌瘤者10例;体胖子宫内膜增厚闭经不孕者2例。
治疗结果:92例女性继发性不孕患者中,治疗时间最长半年,最短一个月。治疗后受孕者90例;2例经治疗后整体病情好转暂未受孕。所有病例服药中均未出现任何不良反应。治疗总有效率97.83%,接近100%。
具体实施方式
实施例1
将艾叶15克、制香附15克、干姜12克、制附子8克、肉桂6克、当归12克、仙灵脾12克、熟地15克、川芎10克、炒白芍12克、桃仁10克、紫石英20克、红花10克、杜仲12克、党参10克、益母草20克、泽兰12克、路路通10克、川牛膝10克、菟丝子15克、神曲20克、桂枝6克、炒白术12克、王不留行15克、巴戟天15克、炙甘草6克放入砂锅内加水约350毫升超过药二-五公分,浸泡三十分钟;上炉煎煮,先武火,煮开后继续文火煎20-30分钟,滤出药汁约250毫升,再加水煎二次滤出250毫升,合计得500毫升。
实施例2
取艾叶12克、制香附12克、干姜12克、制附子8克、肉桂5克、仙灵脾12克、当归12克、熟地15克、川芎10克、炒白芍12克、紫石英25克、桃仁10克、红花10克、杜仲12克、党参10克、益母草20克、泽兰12克、路路通10克、川牛膝10克、菟丝子15克、神曲18克、桂枝7克、炒白术12克、王不留行12克、巴戟天12克、炙甘草6克放入砂锅内加水约350毫升超过药二-五公分,浸泡三十分钟;上炉煎煮,先武火,煮开后继续文火煎至20-30分钟,滤出药汁约250毫升,再加水煎二次滤出250毫升,合计得500毫升。
典型病例:
病例1、张某某,女,30岁,2011年12月24日初诊。主诉:婚后二年夫妻同居未孕。B超多囊卵巢,卵胞发育差,左侧输卵管小囊肿欠通,平素怕冷,四肢凉,能夏不能冬,月经推迟量少色淡、伴血块,临经腰腹凉痛,纳差眠差,舌胖淡,脉弦细迟尺弱。
中医诊断:宫寒不孕。
西医诊断:继发性不孕。
辩证:属阳虚寒凝,络脉瘀阻。
给于实施例1方水煎服,早晚二次分服250毫升。五个疗程受孕生一男婴,现已四岁。
病例2、刘某某,女,28岁,2012年2月6日初诊。婚后二年夫妻同居未孕。B超:子宫小肌瘤多囊卵巢,右侧输卵管欠通,平素怕冷,经迟量少色暗淡成块,下腹凉痛,纳差乏力,舌胖暗淡,脉弦迟尺涩。
中医诊断宫寒不孕(多囊卵巢,子宫肌瘤,输卵管欠通)。
西医诊断:继发性不孕。
辨证:属阳虚寒凝,胞脉瘀阻。
给于实施例2方水煎服,早晚二次分服250毫升。四个疗程生一女孩,现已二岁。
Claims (2)
1.一种治疗婚久继发不孕的中药组合物,其特征在于:按重量计,由下述组分制成:
艾叶10-15份,制香附10-15份,干姜10-15份,制附子6-9份,肉桂4-6份,仙灵脾10-15份,当归10-15份,熟地12-20份,川芎6-12份,炒白芍10-15份,紫石英20-30份,桃仁8-12份,红花6-12份,杜仲10-15份,党参8-12份,益母草20-30份,泽兰10-15份,路路通8-12份,川牛膝8-12份,菟丝子10-15份,神曲15-20份,桂枝6-8份,炒白术10-15份,王不留行10-15份,巴戟天10-15份,炙甘草5-8份,水适量。
2.如权利要求1所述的治疗婚久继发不孕的中药组合物,其特征在于:按重量计,由下述组分制成:艾叶12份、制香附12份、干姜12份、制附子8份、肉桂5份、仙灵脾12份、当归12份、熟地15份、川芎10份、炒白芍12份、紫石英25份、桃仁10份、红花10份、杜仲12份、党参10份、益母草20份、泽兰12份、路路通10份、川牛膝10份、菟丝子15份、神曲18份、桂枝7份、炒白术12份、王不留行12份、巴戟天12份、炙甘草6克,水适量。
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