CN104524305A - Mouth wash relieving toothache and preparation method thereof - Google Patents
Mouth wash relieving toothache and preparation method thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/536—Prunella or Brunella (selfheal)
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- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses mouth wash relieving toothache. The mouth wash comprises, by weight, 8-12 parts of asarum (added at end), 10-20 parts of radix angelicae, 9-16 parts of gallnuts, 10-15 parts of halite, 8-15 parts of burdock, 6-12 parts of semen oroxyli, 10-16 parts of manyleaf paris rhizome, 5-10 parts of selfheal, 4-9 parts of caltrop, 8-12 parts of rhizoma anemarrhenae, 5-10 parts of seeds of feather cockscomb and 8-15 parts of lalang grass rhizome. The mouth wash is prepared by traditional Chinese medicine materials in a traditional extraction method, and stability of effective constituents is ensured. According to the traditional Chinese medicine principle and toothache pathology and etiology, compatibility of medicines is precise, the mouth wash has the effects of clearing heat-fire, relieving pain, diminishing inflammation, removing stasis, reducing swellings and the like. According to clinic trial verification results, the prepared mouth wash operates quickly, is good in treatment effect, and can achieve the treatment effect of treating both principal and secondary aspect of disease.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of collutory and the preparation method of alleviating toothache.
Background technology
Toothache refers to the pain that tooth causes because of a variety of causes, is one of symptom common in oral disease, is found in the dental caries of western medicine, pulpitis, apical periodontitis and dentin hypersensitiveness etc.Toothache outbreak or increase the weight of when meeting hot and cold, sour, sweet etc. stimulation, belongs to " gingival atrophy ", " osteomyelitis of the maxillary bone " category of the traditional Chinese medical science.That has a toothache shows as red swelling of gingiva, chance caloric stimulation pain, buccal swelling etc.Toothache is caused by gingivitis, periodontitis, decayed tooth or Fractured teeth caused by dental pulp (dental nerve) infection mostly.Toothache belongs to the external reaction of tooth defect, and be likely that the gingiva around dental caries, dental pulp or canine tooth is infected, premolar teeth occurs that slight crack also can cause toothache, is only sometimes that dish bits are stuck in teeth space and cause discomfort.The traditional Chinese medical science is thought: the evil poison of wind heat invasion and attack wind-fire is invaded, and injures tooth body and gingiva meat, evilly poly-ly not to fall apart, and QI and blood is detained, and air pocket is obstructed, stasis blocking venation and be disease.Further, hands, Foot yangming Channel arteries and veins are respectively lower tooth, upper tooth, attack meridians outside large intestine, stomach internal organs accumulated heat or ailment said due to cold or exposure, strongly fragrant in Yang Ming fire-transformation, pathogenic fire follow through upper inflammation send out toothache.Kidney governing bones, tooth being the surplus of the bone, deficiency of kidney yin, hyperactivity of deficient fire also can cause toothache.Also have the thing of the sweet acid of polyphagia, ability to speak is unclean, dirty dirty erosion tooth and the person of having a pain.Therefore, the traditional Chinese medical science thinks that toothache is caused by the reasons such as diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, excessiveness of stomach-fire, hyperactivity of fire of suffering from a deficiency of the kidney, worm-eaten tooth.The Therapeutic Method of having a toothache has many kinds, generally adopts Drug therapy.A lot of people commonly uses metronidazole, ibuprofen Western medicine etc. and relieves the pain.The Chinese patent literature of publication number CN104107277 A (application number 201410313459.7) discloses a kind of collutory alleviating toothache and preparation method thereof, and it is made up of tcm components concentrated solution I 20-30%, the concentrated liquid of tradition Chinese medicine II 10-20%, MAJIAO liquid 3-10%, ibuprofen 2-8%, aspirin 2-8%, metronidazole 5-10%, chlorphenamine 2-5%, Borneolum Syntheticum 1-5% and water 20-40%; Described the concentrated liquid of tradition Chinese medicine I is extracted by following raw material, concentrated make: Zaocys, Rhizoma Typhonii, Rhizoma alpiniae chinensis, Radix Angelicae Pubescentis, Herba Taraxaci, Radix Actinidiae Chinensis, Myrrha, Calculus Bovis, Radix Sophorae Tonkinensis, Radix Sophorae Flavescentis, Scorpio, Fructus Viticis, Rhizoma Panacis Majoris and moisture content; Described the concentrated liquid of tradition Chinese medicine II is extracted by following raw material, concentrated make: careless Radix Clematidis, Flos Carthami part, catechu, Radix Notoginseng and water; Described MAJIAO liquid by MAJIAO raw material extracting in water, concentrated to make.The Chinese patent literature of publication number CN 103735750 A (application number 201410027572.9) discloses a kind of bag bubble collutory for the treatment of toothache, main Chinese medicinal materials has: Ampelopsis grossedentata 5-20%, Folium Polygoni Cuspidati 10-30%, Fructus Zanthoxyli 10-30%, Herba Asari 5-10%, Sal 5-30%.The Chinese patent literature of publication number CN 104069012 A (application number 201310105244.1) discloses tooth pain relieving Anti-caries mouthwash, is made up of sodium carbonate, sodium bicarbonate and water.
Western medicine toothache is cured the symptoms, not the disease, and long-term taking has side effect, large to human injury, treatment by Chinese herbs side effect is little, can not develop immunity to drugs, the case utilizing active ingredient of Chinese herbs to be developed into collutory in recent years gets more and more, but still little for the collutory kind alleviating toothache, therefore necessaryly works out a kind of collutory effectively alleviating toothache fast.
Summary of the invention
For the defect of prior art, the object of this invention is to provide and a kind ofly prepare the collutory and preparation method of alleviating toothache simply, safely and effectively.
Technical scheme of the present invention is:
Alleviate the collutory of toothache, be prepared from primarily of following bulk drugs, be weight portion: Herba Asari (entering afterwards) 8-12, Radix Angelicae Dahuricae 10-20, Galla Chinensis 9-16, halite 10-15, Fructus Arctii 8-15, Semen Oroxyli 6-12, Rhizoma Paridis 10-16, Spica Prunellae 5-10, Fructus Tribuli 4-9, Rhizoma Anemarrhenae 8-12, Semen Celosiae 5-10, Rhizoma Imperatae 8-15.
In preferred scheme, Herba Asari (entering afterwards) 9-11, Radix Angelicae Dahuricae 12-18, Galla Chinensis 10-15, halite 11-14, Fructus Arctii 10-13, Semen Oroxyli 8-10, Rhizoma Paridis 12-14, Spica Prunellae 6-9, Fructus Tribuli 5-8, Rhizoma Anemarrhenae 9-11, Semen Celosiae 6-9, Rhizoma Imperatae 10-13.
Be more preferably, Herba Asari (entering afterwards) 10, the Radix Angelicae Dahuricae 15, Galla Chinensis 12.5, halite 12.5, Fructus Arctii 11.5, Semen Oroxyli 9, Rhizoma Paridis 13, Spica Prunellae 7.5, Fructus Tribuli 6.5, the Rhizoma Anemarrhenae 10, Semen Celosiae 7.5, Rhizoma Imperatae 11.5.
The described preparation method alleviating the collutory of toothache is:
(1) get Fructus Arctii decontamination, clean, be placed in pot and boil together with Oryza glutinosa, boil to Oryza glutinosa ripe, remove Oryza glutinosa, dry in the air cool;
(2) getting Testa Tritici to fry to smoldering, adding and picking the clean Rhizoma Anemarrhenae, fry to yellow, sieve removes Testa Tritici, then it is vexed to add saline, rear taking-up, and section, dries;
(3) other medical materials (except Herba Asari, halite) are got, cleaning, drying, pulverize, load in penetrating bag together with step (1) (2) made medical material, then be placed in non iron container, after soaking, ebuillition of heated, after 10 minutes, adds the Herba Asari of pulverizing, continues to decoct, Guan Huo, filter, leave standstill 8 hours, again filter;
(4) halite is ground into medicated powder, add in step (3) made filtrate, stir while adding, carry out homogenizing after stirring, finally namely obtain collutory.
The preparation method of the collutory of described alleviation toothache, the mass ratio of step (1) Oryza glutinosa and Fructus Arctii is 2: 1.
The preparation method of the collutory of described alleviation toothache, and step (2) saline vexed 2-4 hour (preferred, then add saline vexed 2.2 hours-3.8 hours; Be more preferably, then add saline vexed 3 hours).
The preparation method of the collutory of described alleviation toothache, step (3) is soaked and (preferably, is soaked 30-40 minute in 20-50 minute; Be more preferably, soak 35 minutes).
The preparation method of the collutory of described alleviation toothache, step (3) adds the Herba Asari of pulverizing, and (preferred, continuation decocts 16-19 minute to continue to decoct 15-20 minute; Be more preferably, continue decoction 17 minutes).
The preparation method of the collutory of described alleviation toothache, step (3) is filtered and is adopted sieve aperture 80 object nylon silk.
Present invention also offers the application of collutory when preparing the medicine alleviating toothache of described alleviation toothache.
The collutory of alleviation toothache provided by the invention is through putting into practice for many years, and clinical research obtains, scientific formula, easy to use.In addition, excellent results of the present invention also shows:
1, the present invention uses Chinese medicine material, adopts traditional extraction process to obtain, and ensures the stable of effective ingredient;
2, this prescription is according to Chinese medicine principle and the toothache pathology cause of disease, and rigorous compatibility, has the effects such as clearing away heat-fire, analgesic antiphlogistic, mass dissipating and swelling eliminating;
3, the made collutory of the present invention is verified through clinical trial, instant effect, and good effect can reach the therapeutic effect for the treatment of both the principal and secondary aspects of a disease.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
Embodiment 1 alleviates the collutory of toothache, is prepared from, every part of 5g: Herba Asari (entering afterwards) 8 parts primarily of following bulk drugs, the Radix Angelicae Dahuricae 10 parts, Galla Chinensis 9 parts, halite 10 parts, Fructus Arctii 8 parts, Semen Oroxyli 6 parts, Rhizoma Paridis 10 parts, Spica Prunellae 5 parts, Fructus Tribuli 4 parts, the Rhizoma Anemarrhenae 8 parts, Semen Celosiae 5 parts, Rhizoma Imperatae 8 parts.
The preparation method of the collutory of above-mentioned alleviation toothache is:
(1) get Fructus Arctii decontamination, clean, be placed in pot and boil together with Oryza glutinosa (Oryza glutinosa is 2: 1 with the mass ratio of Fructus Arctii), boil to Oryza glutinosa ripe, remove Oryza glutinosa, dry in the air cool;
(2) getting Testa Tritici to fry to smoldering, adding and picking the clean Rhizoma Anemarrhenae, fry to yellow, sieve removes Testa Tritici, then adds saline vexed 2 hours, rear taking-up, and section, dries;
(3) other medical materials (except Herba Asari, halite) are got, cleaning, drying, pulverize, load in penetrating bag together with step (1) (2) made medical material, then be placed in non iron container, after soaking 20 minutes, ebuillition of heated, after 10 minutes, adds the Herba Asari of pulverizing, continues decoction 15 minutes, Guan Huo, adopt sieve aperture 80 object nylon silk to filter, leave standstill 8 hours, again filter;
(4) halite is ground into medicated powder, add in step (3) made filtrate, stir while adding, carry out homogenizing after stirring, finally namely obtain collutory.
The instructions of taking of the collutory of toothache is alleviated in the present invention: after gargling with clear water, collutory is contained in mouth 2-5 minute and spues, and continuously containing 2-3 time, does not drink water, takes food or gargles in 30 minutes afterwards.Taken three times a day, 5 days courses for the treatment of.
Embodiment 2 alleviates the collutory of toothache, is prepared from, every part of 5g: Herba Asari (entering afterwards) 12 parts primarily of following bulk drugs, the Radix Angelicae Dahuricae 20 parts, Galla Chinensis 16 parts, halite 15 parts, Fructus Arctii 15 parts, Semen Oroxyli 12 parts, Rhizoma Paridis 16 parts, Spica Prunellae 10 parts, Fructus Tribuli 9 parts, the Rhizoma Anemarrhenae 12 parts, Semen Celosiae 10 parts, Rhizoma Imperatae 15 parts.
The preparation method alleviating the collutory of toothache is:
(1) get Fructus Arctii decontamination, clean, be placed in pot and boil together with Oryza glutinosa (Oryza glutinosa is 2: 1 with the mass ratio of Fructus Arctii), boil to Oryza glutinosa ripe, remove Oryza glutinosa, dry in the air cool;
(2) getting Testa Tritici to fry to smoldering, adding and picking the clean Rhizoma Anemarrhenae, fry to yellow, sieve removes Testa Tritici, then adds saline vexed 4 hours, rear taking-up, and section, dries;
(3) other medical materials (except Herba Asari, halite) are got, cleaning, drying, pulverize, load in penetrating bag together with step (1) (2) made medical material, then be placed in non iron container, after soaking 50 minutes, ebuillition of heated, after 10 minutes, adds the Herba Asari of pulverizing, continues decoction 20 minutes, Guan Huo, adopt sieve aperture 80 object nylon silk to filter, leave standstill 8 hours, again filter;
(4) halite is ground into medicated powder, add in step (3) made filtrate, stir while adding, carry out homogenizing after stirring, finally namely obtain collutory.
Model case: xxx, man, 10 years old.Happiness is had a sweet tooth, after eating up sweet food evening, and the custom of not brushing teeth, there is toothache in nearly first quarter moon, when eating the food of hard food or sour-sweet, caloric stimulation, pain symptom increases the weight of, and the state of an illness is day by day serious, even affect diet, be difficult to chew, be in and take amoxicillin, antibiotic medicine, have no improvement, occur hurt like hell, father and mother bring and seek medical advice, and are diagnosed as decayed tooth toothache on inspection.
After carrying out artificial crown repairing and treating, use the present embodiment gained to alleviate the collutory of toothache, use after one day, toothache alleviates to some extent, redness has and slightly disappears, and uses two days later, red and swollenly disappears, pain obviously alleviates, can normally take food, use after three days, pain is also vanished from sight, patient feels good, recovery from illness.
Embodiment 3 alleviates the collutory of toothache, is prepared from, every part of 5g: Herba Asari (entering afterwards) 9 parts primarily of following bulk drugs, the Radix Angelicae Dahuricae 12 parts, Galla Chinensis 10 parts, halite 11 parts, Fructus Arctii 10 parts, Semen Oroxyli 8 parts, Rhizoma Paridis 12 parts, Spica Prunellae 6 parts, Fructus Tribuli 5 parts, the Rhizoma Anemarrhenae 9 parts, Semen Celosiae 6 parts, Rhizoma Imperatae 10 parts.
The preparation method alleviating the collutory of toothache is:
(1) get Fructus Arctii decontamination, clean, be placed in pot and boil together with Oryza glutinosa (Oryza glutinosa is 2: 1 with the mass ratio of Fructus Arctii), boil to Oryza glutinosa ripe, remove Oryza glutinosa, dry in the air cool;
(2) getting Testa Tritici to fry to smoldering, adding and picking the clean Rhizoma Anemarrhenae, fry to yellow, sieve removes Testa Tritici, then adds saline vexed 2.2 hours, rear taking-up, and section, dries;
(3) other medical materials (except Herba Asari, halite) are got, cleaning, drying, pulverize, load in penetrating bag together with step (1) (2) made medical material, then be placed in non iron container, after soaking 30 minutes, ebuillition of heated, after 10 minutes, adds the Herba Asari of pulverizing, continues decoction 16 minutes, Guan Huo, adopt sieve aperture 80 object nylon silk to filter, leave standstill 8 hours, again filter;
(4) halite is ground into medicated powder, add in step (3) made filtrate, stir while adding, carry out homogenizing after stirring, finally namely obtain collutory.
Embodiment 4 alleviates the collutory of toothache, is prepared from, every part of 5g: Herba Asari (entering afterwards) 11 parts primarily of following bulk drugs, the Radix Angelicae Dahuricae 18 parts, Galla Chinensis 15 parts, halite 14 parts, Fructus Arctii 13 parts, Semen Oroxyli 10 parts, Rhizoma Paridis 14 parts, Spica Prunellae 9 parts, Fructus Tribuli 8 parts, the Rhizoma Anemarrhenae 11 parts, Semen Celosiae 9 parts, Rhizoma Imperatae 13 parts.
The preparation method alleviating the collutory of toothache is:
(1) get Fructus Arctii decontamination, clean, be placed in pot and boil together with Oryza glutinosa (Oryza glutinosa is 2: 1 with the mass ratio of Fructus Arctii), boil to Oryza glutinosa ripe, remove Oryza glutinosa, dry in the air cool;
(2) getting Testa Tritici to fry to smoldering, adding and picking the clean Rhizoma Anemarrhenae, fry to yellow, sieve removes Testa Tritici, then adds saline vexed 3.8 hours, rear taking-up, and section, dries;
(3) other medical materials (except Herba Asari, halite) are got, cleaning, drying, pulverize, load in penetrating bag together with step (1) (2) made medical material, then be placed in non iron container, after soaking 40 minutes, ebuillition of heated, after 10 minutes, adds the Herba Asari of pulverizing, continues decoction 19 minutes, Guan Huo, adopt sieve aperture 80 object nylon silk to filter, leave standstill 8 hours, again filter;
(4) halite is ground into medicated powder, add in step (3) made filtrate, stir while adding, carry out homogenizing after stirring, finally namely obtain collutory.
Model case: xxx, female, 45 years old.Main suit: when nearly first quarter moon is brushed teeth, have hemorrhage during gingiva, rear appearance redness, distending pain, gum edge is thickening, is no longer close to facing, and appetite declines, and because work has some setbacks, mood is irritated, in a few days ago evening, occurs toothache in bed, medical check, is diagnosed as toothache caused by gingivitis.
Patient does not like taking medicine, and thus use the present embodiment gained to alleviate the collutory of toothache, after using twice, tenderness alleviates, and redness obviously disappears, and uses after three days, and patient's toothache and red swelling of gingiva disappear, mood improvement, appetite recovery, can normal diet, self-induction recovery from illness.
Embodiment 5 alleviates the collutory of toothache, is prepared from, every part of 6g: Herba Asari (entering afterwards) 10 parts primarily of following bulk drugs, the Radix Angelicae Dahuricae 15 parts, Galla Chinensis 12.5 parts, halite 12.5 parts, Fructus Arctii 11.5 parts, Semen Oroxyli 9 parts, Rhizoma Paridis 13 parts, Spica Prunellae 7.5 parts, Fructus Tribuli 6.5 parts, the Rhizoma Anemarrhenae 10 parts, Semen Celosiae 7.5 parts, Rhizoma Imperatae 11.5 parts.
The preparation method alleviating the collutory of toothache is:
(1) get Fructus Arctii decontamination, clean, be placed in pot and boil together with Oryza glutinosa (Oryza glutinosa is 2: 1 with the mass ratio of Fructus Arctii), boil to Oryza glutinosa ripe, remove Oryza glutinosa, dry in the air cool;
(2) getting Testa Tritici to fry to smoldering, adding and picking the clean Rhizoma Anemarrhenae, fry to yellow, sieve removes Testa Tritici, then adds saline vexed 3 hours, rear taking-up, and section, dries;
(3) other medical materials (except Herba Asari, halite) are got, cleaning, drying, pulverize, load in penetrating bag together with step (1) (2) made medical material, then be placed in non iron container, after soaking 35 minutes, ebuillition of heated, after 10 minutes, adds the Herba Asari of pulverizing, continues decoction 17 minutes, Guan Huo, adopt sieve aperture 80 object nylon silk to filter, leave standstill 8 hours, again filter;
(4) halite is ground into medicated powder, add in step (3) made filtrate, stir while adding, carry out homogenizing after stirring, finally namely obtain collutory.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Asari: base is former: be the dry herb of aristolochiaceae plant Herba Asari, Seoul Herba Asari or magnificent Herba Asari.Nature and flavor: pungent, temperature.Gui Jing: GUIXIN, lung, kidney channel.Function cures mainly: expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.
The Radix Angelicae Dahuricae: base is former: be the dry root of the umbellate form section plant Radix Angelicae Dahuricae or Radix angelicae dahuricae.Nature and flavor: pungent, temperature.Gui Jing: return stomach, large intestine, lung meridian.Function cures mainly: loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.
Galla Chinensis: base is former: be the insect gall of doubly Aphidiadae insecticide horned gall aphid or melaphis peitan Tsai et Tang formation on the trees such as its host's Fructus rhois chinensis, potanin sumac or Radix Rhois Sinicae.Nature and flavor: sour, puckery, cold.Gui Jing: return lung, large intestine, kidney channel.Function cures mainly: pathogenic fire reducing of astringing the lung, relieving diarrhea with astringents, and arresting sweating stops blooding, removing dampness sore.For chronic cough of deficiency lung, lung-heat phlegmatic cough, chronic diarrhea chronic dysentery, night sweat, quenches one's thirst, hemorrhoidal bleeding of having blood in stool, traumatic hemorrhage, carbuncle sore tumefacting virus, Skin wet and rotten.
Halite: base is former: be the crystalline solid of chloride-based halite race mineral halite.Nature and flavor: salty, cold.Gui Jing: GUIXIN, kidney, urinary bladder channel.Function cures mainly: purge heat, removing heat from blood, and improving eyesight is moisturized, and cures mainly hematuria, and spit blood, radula is hemorrhage, conjunctival congestion and swelling pain, the rotten string of wind-eye, toothache, constipation.
Fructus Arctii: base is former: be the dry mature fruit of feverfew Fructus Arctii.Nature and flavor: pungent, bitter, cold.Gui Jing: attach to the lung and stomach meridians.Function cures mainly: dispelling wind and heat pathogens, lung qi dispersing rash, resolving toxin and disinhibiting the throat.For anemopyretic cold, cough with copious phlegm, measles, rubella, laryngopharynx swelling and pain, mumps erysipelas, carbuncle sore tumefacting virus.
Semen Oroxyli: base is former: be the dry mature seed of Bignoniaceae plant oroxylum indicum.Nature and flavor: bitter, sweet, cool.Gui Jing: return lung, liver, stomach warp.Function cures mainly: removing heat from the lung and relieving sorethroat, dispersing the stagnated liver-QI for regulating the stomach.For cough due to lung-heat, sore throat, hoarseness, stomachache due to hyperactive liver-QI attacking the stomach.
Rhizoma Paridis: base is former: be the rhizome of liliaceous plant Rhizoma Paridis, RHIZOMA PARIDIS and several congeners thereof.Nature and flavor: toil, cold, poisonous.Gui Jing: enter the heart, Liver Channel.Function cures mainly: heat-clearing and toxic substances removing, antiasthmatic-antitussive, and relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion.Control carbuncle, furuncle, scrofula, sore throat, chronic tracheitis, infantile convulsion is twitched, snake bite and insect sting.
Spica Prunellae: base is former: be the dry fruit ear of labiate Spica Prunellae.Nature and flavor: pungent, bitter, cold.Gui Jing: return liver, gallbladder meridian.Function cures mainly: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Fructus Tribuli: base is former: be the fruit of zygophyllaceae plant Fructus Tribuli.Nature and flavor: pungent, bitter, tepor; Slightly poisonous.Gui Jing: return Liver Channel.Function cures mainly: suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, and improving eyesight is antipruritic.Dizzy for having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus.
The Rhizoma Anemarrhenae: base is former: be the dry rhizome of the liliaceous plant Rhizoma Anemarrhenae.Nature and flavor: bitter, sweet, cold.Gui Jing: return lung, stomach, kidney channel.Function cures mainly: clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Semen Celosiae: base is former: be the dry mature seed of amaranthaceous plant Herba Celosiae argenteae.Nature and flavor: bitter, are slightly cold.Gui Jing: return Liver Channel.Function cures mainly: liver heat removing, improving eyesight, nebula removing.For liver-heat conjunctival congestion, nebula of looking unfamiliar film, blurring of vision, dizziness due to liver-fire.
Rhizoma Imperatae: base is former: be the dry rhizome of grass Herba Imperatae.Nature and flavor: sweet, cold.Gui Jing: return lung, stomach, urinary bladder channel.Function cures mainly: cooling blood for hemostasis, clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria; Acute nephritis edema.
Test example 1 gained of the present invention alleviates the clinical practice of the collutory (embodiment 5) of toothache:
The patient that 387 examples are diagnosed as infections of dental pulp appearance toothache caused by gingivitis, periodontitis, dental caries or Fractured teeth is filtered out, wherein women 176 example, male 211 example, oldest 56 years old, minimal ages 20 years old, 38.4 years old mean age from hospital-based outpatient dental clinic.All patients, all without severe systemic infection and systemic disease, test and within first 3 months, do not take antibiotic and use collutory, without smoking and excessive drinking custom, do not participate in other similar experimental studies simultaneously.
Patient is divided into two groups at random, experimental group 237 example and matched group 150 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (P > 0.05), there is comparability.Experimental group takes the made collutory alleviating toothache of the present invention, and using method: after gargling with clear water, is contained in mouth 2-5 minute and spues by collutory, continuously containing 2-3 time, do not drink water, take food or gargle in 30 minutes afterwards.Use three every day, 5 days courses for the treatment of.Matched group take other medicament or collutory as artificial Calculus Bovis's metronidazole, clean plain collutory, clean must conventional dose or the collutory such as safe collutory.Treatments period carries out Continuous Observation to two groups of patients, and record symptom and change, added up therapeutic outcome after one week.
Curative effect situation criterion: effective: the clinical symptom disappearance such as toothache, red swelling of gingiva, chance caloric stimulation is without exception; Effective: the clinical symptoms such as toothache, red swelling of gingiva obviously alleviate, the pain of answering thing to still have acid swollen with caloric stimulation or chew; Invalid: the symptoms such as toothache, redness are unchanged or increase the weight of.
Result of the test: in experimental group, cures 133 examples (56.1%), effective 95 examples (40.1%), and no effect 9 (3.8%), experimental group total effective rate is 96.2%.
In matched group, cure 54 examples (36.0%), effective 73 examples (48.7%), invalid 23 examples (15.3%), the total effective rate of matched group is 84.7%.
A table 1 liang group patient has a toothache alleviation situation
In process of the test, experimental group patients symptomatic is eased required time short compared with matched group (the results are shown in Table 1), and also all comparatively matched group patient is good for experimental group patient diet and Health restoration situation.Known in conjunction with the treatment statistical result of two groups: the treatment of experimental group toothache successful is better than matched group, the present invention is made alleviate the collutory of toothache can the toothache malaise symptoms of effective reduction of patient rapidly.And in therapeutic process, untoward reaction does not appear in experimental group patient, and products made thereby of the present invention is described, safety has no side effect.
In the medical material that formula of the present invention is selected, Herba Asari, Radix Angelicae Dahuricae expelling wind and cold, understand things pain-stopping; Galla Chinensis is astringed the lung pathogenic fire reducing, astringing intestine to stop diarrhea pathogenic fire purging; Purge heat removing heat from blood, improving eyesight of halite is moisturized; Fructus Arctii and Semen Oroxyli dispelling wind and heat pathogens, resolving toxin and disinhibiting the throat; Rhizoma Paridis heat-clearing and toxic substances removing; Spica Prunellae relieves inflammation or internal heat, eliminating stagnation, detumescence; Fructus Tribuli suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind; Rhizoma Anemarrhenae clearing away heat-fire, promote the production of body fluid and moisturize; Semen Celosiae liver heat removing and eyesight improving, nebula removing; Rhizoma Imperatae cooling blood for hemostasis, clearing away heat and promoting diuresis, multiple effective medical material share, the effects such as common performance clearing away heat-fire, analgesic antiphlogistic, mass dissipating and swelling eliminating, thus have good anti-inflammatory analgetic effect for the toothache caused by gingivitis, periodontitis, dental caries, decayed tooth and other odontopathies.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. alleviate the collutory of toothache, it is characterized in that, be prepared from primarily of following bulk drugs, be weight portion: Herba Asari (entering afterwards) 8-12, Radix Angelicae Dahuricae 10-20, Galla Chinensis 9-16, halite 10-15, Fructus Arctii 8-15, Semen Oroxyli 6-12, Rhizoma Paridis 10-16, Spica Prunellae 5-10, Fructus Tribuli 4-9, Rhizoma Anemarrhenae 8-12, Semen Celosiae 5-10, Rhizoma Imperatae 8-15.
2. the collutory alleviating toothache as claimed in claim 1, is characterized in that, Herba Asari (entering afterwards) 9-11, Radix Angelicae Dahuricae 12-18, Galla Chinensis 10-15, halite 11-14, Fructus Arctii 10-13, Semen Oroxyli 8-10, Rhizoma Paridis 12-14, Spica Prunellae 6-9, Fructus Tribuli 5-8, Rhizoma Anemarrhenae 9-11, Semen Celosiae 6-9, Rhizoma Imperatae 10-13.
3. the collutory alleviating toothache as claimed in claim 1, is characterized in that, Herba Asari (entering afterwards) 10, the Radix Angelicae Dahuricae 15, Galla Chinensis 12.5, halite 12.5, Fructus Arctii 11.5, Semen Oroxyli 9, Rhizoma Paridis 13, Spica Prunellae 7.5, Fructus Tribuli 6.5, the Rhizoma Anemarrhenae 10, Semen Celosiae 7.5, Rhizoma Imperatae 11.5.
4. the preparation method of the collutory of the alleviation toothache as described in as arbitrary in claim 1-3, it is characterized in that, step is:
(1) get Fructus Arctii decontamination, clean, be placed in pot and boil together with Oryza glutinosa, boil to Oryza glutinosa ripe, remove Oryza glutinosa, dry in the air cool;
(2) getting Testa Tritici to fry to smoldering, adding and picking the clean Rhizoma Anemarrhenae, fry to yellow, sieve removes Testa Tritici, then it is vexed to add saline, rear taking-up, and section, dries;
(3) other medical materials (except Herba Asari, halite) are got, cleaning, drying, pulverize, load in penetrating bag together with step (1) (2) made medical material, then be placed in non iron container, after soaking, ebuillition of heated, after 10 minutes, adds the Herba Asari of pulverizing, continues to decoct, Guan Huo, filter, leave standstill 8 hours, again filter;
(4) halite is ground into medicated powder, add in step (3) made filtrate, stir while adding, carry out homogenizing after stirring, finally namely obtain collutory.
5. the preparation method alleviating the collutory of toothache as claimed in claim 4, it is characterized in that, the mass ratio of step (1) Oryza glutinosa and Fructus Arctii is 2: 1.
6. the as claimed in claim 4 preparation method alleviating the collutory of toothache, is characterized in that, and step (2) saline vexed 2-4 hour (preferred, then add saline vexed 2.2 hours-3.8 hours; Be more preferably, then add saline vexed 3 hours).
7. the preparation method alleviating the collutory of toothache as claimed in claim 4, is characterized in that, step (3) is soaked and (preferably, soaked 30-40 minute in 20-50 minute; Be more preferably, soak 35 minutes).
8. the preparation method of the collutory of alleviation toothache as claimed in claim 4, it is characterized in that, step (3) adds the Herba Asari of pulverizing, and (preferred, continuation decocts 16-19 minute to continue to decoct 15-20 minute; Be more preferably, continue decoction 17 minutes).
9. the preparation method alleviating the collutory of toothache as claimed in claim 4, is characterized in that, what adopt when step (3) is filtered is sieve aperture 80 object nylon silk.
10. the application of collutory when preparing the medicine alleviating toothache of the alleviation toothache as described in as arbitrary in claim 1-3.
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| CN105796843A (en) * | 2016-03-14 | 2016-07-27 | 薛之渊 | External medicament for treating toothaches |
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| CN102920942A (en) * | 2012-11-20 | 2013-02-13 | 周少勇 | Medicine for treating acute toothache |
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Application publication date: 20150422 |