CN104524178A - 一种治疗面瘫的中药组合物 - Google Patents

一种治疗面瘫的中药组合物 Download PDF

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CN104524178A
CN104524178A CN201510051276.7A CN201510051276A CN104524178A CN 104524178 A CN104524178 A CN 104524178A CN 201510051276 A CN201510051276 A CN 201510051276A CN 104524178 A CN104524178 A CN 104524178A
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郎波
张禄
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LANG WENYI
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Abstract

本发明涉及一种治疗面瘫的中药组合物，它包含下列重量份的物质：防风20-30份、荆芥15-30份、秦艽20-30份、白芷20-30份、菊花20-40份、金银花20-40份、僵虫20-30份、白附子10-20份、全蝎20-30份、蜈蚣30-60份、柴胡20-30份、红花20-30份、桃仁20-30份、当归20-30份、丹参30-40份、麦冬20-30份和赤芍20-30份。本发明所述的中药组合物互相影响，协同作用，疗效显著，非常值得大力推广。

Description

一种治疗面瘫的中药组合物
技术领域
本发明涉及医药领域，具体来说涉及一种护理治疗面瘫的中药组合物。
背景技术
周围性面瘫又称贝耳麻痹，是指原因不明、急性发病的单侧周围性面神经麻痹、夏、秋两季发病率较高，系常见病、中医学称为″口眼歪斜″，任何年龄均可发病，男性略多，多数患者为20-40岁、通常急性起病，于数小时或1-2d内达高峰、病初可有下颚角或耳后疼痛，主要症状为一侧面部表情肌瘫痪，额纹消失，不能皱眉，眼裂闭合不全，病侧鼻唇沟变浅、嘴角歪向健侧。
发明内容
本发明的目的是提供一种治疗面瘫的中药组合物。
为了实现本发明的目的，本发明提供一种治疗面瘫的中药组合物，它包含下列重量份的物质：防风20-30份、荆芥15-30份、秦艽20-30份、白芷20-30份、菊花20-40份、金银花20-40份、僵虫20-30份、白附子10-20份、全蝎20-30份、蜈蚣30-60份、柴胡20-30份、红花20-30份、桃仁20-30份、当归20-30份、丹参30-40份、麦冬20-30份和赤芍20-30份。
优选地，所述的治疗面瘫的中药组合物包含下列重量份的物质：防风25份、荆芥20份、秦艽25份、白芷25份、菊花30份、金银花30份、僵虫25份、白附子15份、全蝎25份、蜈蚣35份、柴胡25份、红花25份、桃仁25份、当归25份、丹参35份、麦冬25份和赤芍25份。
优选地，所述的治疗面瘫的中药组合物还包含下列重量份的物质：凤眼果15份、狗牙根13份、鸭脚艾10份、铁马鞭12份、梅花草8份、杜仲20份、蛇藤12份、桑寄生12份、散血莲10份、荷叶15份、葫芦藓12份、花酸苔15份、水珠草12份、云苔草10份和罗布麻叶10份。
优选地，所述中药组合物可以是片剂、分散片、胶囊剂、丸剂或软膏剂。
本发明还提供组合物在制备治疗面瘫的中药中的用途，所述组合物包含下列重量份的物质：防风20-30份、荆芥15-30份、秦艽20-30份、白芷20-30份、菊花20-40份、金银花20-40份、僵虫20-30份、白附子10-20份、全蝎20-30份、蜈蚣30-60份、柴胡20-30份、红花20-30份、桃仁20-30份、当归20-30份、丹参30-40份、麦冬20-30份和赤芍20-30份。
优选地，所述组合物包含下列重量份的物质：防风25份、荆芥20份、秦艽25份、白芷25份、菊花30份、金银花30份、僵虫25份、白附子15份、全蝎25份、蜈蚣35份、柴胡25份、红花25份、桃仁25份、当归25份、丹参35份、麦冬25份和赤芍25份。
优选地，所述组合物还包含下列重量份的物质：凤眼果15份、狗牙根13份、鸭脚艾10份、铁马鞭12份、梅花草8份、杜仲20份、蛇藤12份、桑寄生12份、散血莲10份、荷叶15份、葫芦藓12份、花酸苔15份、水珠草12份、云苔草10份和罗布麻叶10份。
优选地，所述中药可以是片剂、分散片、胶囊剂、丸剂或软膏剂。
本发明所述的中药组合物互相影响，协同作用，疗效显著，非常值得大力推广。
具体实施方式
下面通过实施例进一步说明本发明。应该理解的是，本发明的实施例是用于说明本发明而不是对本发明的限制。根据本发明的实质对本发明进行的简单改进都属于本发明要求保护的范围。除非另有说明，否则本发明中的百分数是重量百分数。
实施例1本发明的软膏剂
称取防风25克、荆芥20克、秦艽25克、白芷25克、菊花30克、金银花30克、僵虫25克、白附子15克、全蝎25克、蜈蚣35克、柴胡25克、红花25克、桃仁25克、当归25克、丹参35克、麦冬25克和赤芍25克，加入6500毫升水，在回流的条件下加热5小时，过滤，使滤液冷却至室温，加入无水乙醇至醇含量为85体积％，静置过夜，过滤，将滤液蒸干，粉碎，加入凡士林250克，混合均匀，即得。
实施例2本发明的软膏剂
称取防风25克、荆芥20克、秦艽25克、白芷25克、菊花30克、金银花30克、僵虫25克、白附子15克、全蝎25克、蜈蚣35克、柴胡25克、红花25克、桃仁25克、当归25克、丹参35克、麦冬25克、赤芍25克、凤眼果15克、狗牙根13克、鸭脚艾10克、铁马鞭12克、梅花草8克、杜仲20克、蛇藤12克、桑寄生12克、散血莲10克、荷叶15克、葫芦藓12克、花酸苔15克、水珠草12克、云苔草10克和罗布麻叶10克，加入6500毫升水，在回流的条件下加热5小时，过滤，使滤液冷却至室温，加入无水乙醇至醇含量为85体积％，静置过夜，过滤，将滤液蒸干，粉碎，加入凡士林250克，混合均匀，即得。
实验例
诊断标准
参照《临床常见疾病诊疗标准》(陶天遵.临床常见疾病的诊疗标准[M].北京：北京医科大学中国协和医科大学联合出版社，1995：98-99)拟定：(1)发病年龄不定，急性起病，1-5天内达到高峰。(2)临床表现主要为病侧表情肌瘫痪，即额纹消失，眼裂扩大，闭目不严，鼻唇沟变浅，口角下垂，示齿、鼓腮动作不能完成。(3)排除外伤、耳科及桥小脑角部位病变等所致的周围面神经损伤。
根据上述标准，选择100例面瘫患者，其中男58例，女42例，年龄19-63岁，平均33岁；病程最短1天，最长1个月，平均发病时间5天，急性发作期44例，慢性缓解期56例。将患者为两组，分别为治疗组1和治疗组2，每组有50例患者。两组患者性别、年龄、病程、症状均无显著性差异，具有可比性(P＞0.05)。
治疗组1使用实施例1中制备的软膏剂来治疗，每日两次，每次使用20克软膏剂均匀涂抹在双侧太阳穴部，连续治疗10天。
治疗组2使用实施例2中制备的软膏剂来治疗，每日两次，每次使用20克软膏剂均匀涂抹在双侧太阳穴部，连续治疗10天。
疗效标准
治愈：临床症状和体征全部消失，即面肌功能恢复正常，口眼歪斜症状消失，眼睑闭合良好。显效：面肌功能基本恢复，口眼歪斜基本消失，但患侧尚有轻度麻木感觉或说笑时略有口歪。好转：面肌功能部分恢复，口眼歪斜症状减轻，其他症状改善。无效：治疗前后无明显改善。
统计学方法
对实验数据利用SPSS 13.0软件进行处理和分析，计量资料以均数±标准差表示，采用t检验，计数资料采用x2检验，P＜0.05表示差异具有统计学意义。
结果
经过治疗，对于治疗组1，治愈19例，显效12例，好转13例，无效6例，总有效率为88％，对于治疗组2，治愈26例，显效15例，好转9例，总有效率为100％。两组总有效率比较差异有统计学意义(P＜0.05)。并且在治疗过程中两组患者均未发现明显的不良反应。

Claims (8)

1.一种治疗面瘫的中药组合物，其特征在于，它包含下列重量份的物质：防风20-30份、荆芥15-30份、秦艽20-30份、白芷20-30份、菊花20-40份、金银花20-40份、僵虫20-30份、白附子10-20份、全蝎20-30份、蜈蚣30-60份、柴胡20-30份、红花20-30份、桃仁20-30份、当归20-30份、丹参30-40份、麦冬20-30份和赤芍20-30份。
2.根据权利要求1所述的治疗面瘫的中药组合物，其特征在于，它包含下列重量份的物质：防风25份、荆芥20份、秦艽25份、白芷25份、菊花30份、金银花30份、僵虫25份、白附子15份、全蝎25份、蜈蚣35份、柴胡25份、红花25份、桃仁25份、当归25份、丹参35份、麦冬25份和赤芍25份。
3.根据权利要求1或2所述的治疗面瘫的中药组合物，其特征在于，它还包含下列重量份的物质：凤眼果15份、狗牙根13份、鸭脚艾10份、铁马鞭12份、梅花草8份、杜仲20份、蛇藤12份、桑寄生12份、散血莲10份、荷叶15份、葫芦藓12份、花酸苔15份、水珠草12份、云苔草10份和罗布麻叶10份。
4.根据权利要求3所述的治疗面瘫的中药组合物，其特征在于，所述中药组合物可以是片剂、分散片、胶囊剂、丸剂或软膏剂。
5.组合物在制备治疗面瘫的中药中的用途，其特征在于，所述组合物包含下列重量份的物质：防风20-30份、荆芥15-30份、秦艽20-30份、白芷20-30份、菊花20-40份、金银花20-40份、僵虫20-30份、白附子10-20份、全蝎20-30份、蜈蚣30-60份、柴胡20-30份、红花20-30份、桃仁20-30份、当归20-30份、丹参30-40份、麦冬20-30份和赤芍20-30份。
6.根据权利要求5所述的用途，其特征在于，所述组合物包含下列重量份的物质：防风25份、荆芥20份、秦艽25份、白芷25份、菊花30份、金银花30份、僵虫25份、白附子15份、全蝎25份、蜈蚣35份、柴胡25份、红花25份、桃仁25份、当归25份、丹参35份、麦冬25份和赤芍25份。
7.根据权利要求5或6所述的用途，其特征在于，所述组合物还包含下列重量份的物质：凤眼果15份、狗牙根13份、鸭脚艾10份、铁马鞭12份、梅花草8份、杜仲20份、蛇藤12份、桑寄生12份、散血莲10份、荷叶15份、葫芦藓12份、花酸苔15份、水珠草12份、云苔草10份和罗布麻叶10份。
8.根据权利要求7所述的用途，其特征在于，所述中药可以是片剂、分散片、胶囊剂、丸剂或软膏剂。
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CN107582870A (zh) * 2017-10-26 2018-01-16 北京煜煌科技有限公司 一种治疗面瘫的组合物及其制备方法
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CN105125682A (zh) * 2015-09-28 2015-12-09 卞文青 一种用于治疗面瘫的药物制剂
CN107582870A (zh) * 2017-10-26 2018-01-16 北京煜煌科技有限公司 一种治疗面瘫的组合物及其制备方法
CN110787257A (zh) * 2018-07-17 2020-02-14 郎文义 一种治疗面瘫的中药组合物
CN113694145A (zh) * 2021-08-16 2021-11-26 郎文义 一种治疗面瘫的中药组合物

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