CN104519950B - 使aed更快时间进行电击的方法和装置 - Google Patents

使aed更快时间进行电击的方法和装置 Download PDF

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CN104519950B
CN104519950B CN201280074134.7A CN201280074134A CN104519950B CN 104519950 B CN104519950 B CN 104519950B CN 201280074134 A CN201280074134 A CN 201280074134A CN 104519950 B CN104519950 B CN 104519950B
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费查·阿卜丁
林达·萨玛
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Abstract

除了所公开的其他装置和方法以外，本发明公开了一种用于减少在终止心肺复苏(CPR)和施行除颤电击之间的延迟的自动体外除颤器(AED)及其方法。在一个实施例中，所述AED包括获得与患者的心脏活动相对应的ECG信号的ECG传感器以及提供关于心肺复苏的指令的提示装置。所述AED还具有控制系统，其包括被编程用于在终止CPR的指令后运行两个心律分析算法的微处理器。所述两个心律分析算法分析所述ECG信号的片段以识别可电击心律的存在，其中的一个算法相对于另一个算法具有延迟启动。所述AED还包括治疗生成电路，其用于响应于判断可电击心律的存在的所述控制系统而用除颤脉冲处理所述可电击心律。

Description

使AED更快时间进行电击的方法和装置
技术领域
本发明涉及改进的方法和装置，其涉及自动体外除颤器(AED)和心肺复苏(CPR)的综合使用。具体地，本发明涉及AED和方法，其能快速和可靠地在复苏尝试期间确定在心脏骤停的受害者体内可电击心律的存在，从而使在CPR和传递除颤电击之间的延迟最小化成为可能。
背景技术
心脏骤停被广泛理解为重大的公共健康问题以及在世界上的大部分地区导致死亡的主要原因。每年在美国和加拿大约有350,000人遭遇心脏骤停且接受试图复苏。因此，医学界一直在寻求通过CPR和应用除颤电击以更成功地治疗心脏骤停以使经历该类型事件的人士迅速恢复正常心律的方式。几十年前，首次开发了AED以帮助治疗心脏骤停的事件。自创建以来，AED已在公共区域，如办公室、购物中心、体育场和其他高人流区域中变得流行。AED使市民能在公共场所中在心脏急救期间提供医疗帮助，之前，在这些地方无法得到在心脏突发事件的关键早期阶段的帮助。
能够准确检测室性心律失常和不可电击的室上性心律失常的全自动体外除颤器，如在Payne等的美国专利号5,474,574中描述的那些已被开发出来以治疗无人值守的患者。这些装置治疗遭受室性心律失常的受害者且在实时检测可电击心律失常中具有高敏感性和特异性。进一步地，已开发出AED以作为诊断监控装置，其可自动地在医院环境中提供治疗，如在Lin等的美国专利号6,658,290中所述的。
尽管在AED技术中取得了进步，但当前许多AED在实施当前医学建议的综合CPR和AED的使用中不能够完全发挥作用。当今，大多数可用的AED试图对室性心律进行分类并区分可电击室性心律以及所有其他不可电击的心律。这种室性心律的检测和分析提供了ECG波形的某种实时分析。然而，特定AED的功能、准确性和速度在很大程度上取决于用于分析ECG波形的算法和硬件。在许多实施方案中，在AED中使用的算法取决于心率计算和从ECG波形获得的多种形态特性，如在Payne等的美国专利号5474574和Zhang等的美国专利号6480734中公开的ECG波形因数和不规则性。进一步地，为了提供足够的处理能力，当前的AED通常将算法和控制逻辑嵌入微控制器中。
随着在AED领域中取得的进步，在理解人体生理学以及其是如何与医疗保健相关的方面具有了显著的医学进步。在医学研究中的这些进步已导致在处理身体创伤事件的新协议和标准操作程序中的发展。例如，在用于除颤的公共接入协议中，最近的指南已强调需要同时使用CPR和AED并已建议涉及结合有CPR的除颤的包容性方法。
然而，伴随着优势，结合使用CPR和除颤可对AED的操作产生负面影响，这是因为胸外按压和放松已知会在ECG的记录中引入显著的运动伪影。在CPR期间和其之后，在指导救助者按每分钟约100次的规定速率施加胸外按压和放松的情况下，从患者获得干净的信号数据的能力可能是有挑战性的。
除了难于获得干净的ECG信号外，最近已突出了快速地做这件事的重要性，这是因为当前的AHA指南强调了使在CPR和除颤之间的中断最小化的重要性。指南说明，“如果在胸外按压中的中断(用于心律评估、除颤或高级护理)的保持为最小值，则会改善除颤结果”以及“使在停止胸外按压和传递电击之间的间隔最小化(即，使电击前的停顿最小化)改善了电击成功和患者生存的机会”。见发行2010，122：S678和S641。
过去的一些AED实施一种算法，其在救援期间需要干净的ECG信号数据的延长期以将感测的室性心律分类为可电击的。一些需要干净信号的现有技术的公开也讨论了当进行CPR且在依托CPR中的临时中止以获得并进行ECG分析前进行ECG的初步评估。此外，在该领域中最近的学术研究中的大多数均涉及使用能使ECG的整个分析在CPR进行时发生的工具，从而很少需要或不需要中止CPR。因此，已经提出为了进行ECG信号分析的用于识别和过滤CPR伪影的多种技术。然而，这些方法和分析技术中的许多都具有局限性或增加了与提供适当的护理相关的考虑，特别是在最新的AHA指南中。
因此，需要用于快速地评估可电击心律的改进的方法和装置，其使使在CPR和用AED传递除颤电击之间的任何时间段最小化。
发明内容
本发明的各种实施例能够通过提供一种方法和装置，以快速但却准确地判断和验证可电击心律的存在以使CPR和通过救助者传递除颤电击之间的延迟最小化而克服现有技术的问题。
在一个实施例中，提供了一种自动体外除颤器(AED)。该AED包括获得与患者的心脏活动相对应的ECG信号的ECG传感器以及提供关于心肺复苏(CPR)指令的提示装置。进一步地，该AED还具有控制系统，其包括被编程用于在终止CPR的指令后运行两个心律分析算法的微处理器。这两个心律分析算法分析ECG信号的片段以识别可电击心律的存在。两个心律分析算法中的一个提供了延迟启动的可电击心律验证算法。该AED还包括治疗生成电路，其用于响应于判断可电击心律的存在的控制系统而用除颤脉冲处理可电击心律。
在根据本发明的另一个实施例中，公开了一种AED。AED包括获得与患者的心脏活动相应的ECG信号的ECG传感器。AED还包括用于提供CPR指令的指示装置。AED还包括具有微处理器的控制系统，其中控制系统适于使用第一算法在ECG信号的第一片段中确定可电击心律的存在。控制系统还适于使用第二验证算法在ECG信号的第二片段中确定可电击心律的存在。第一算法和第二验证算法并行运行并分析ECG信号的片段。在该实施例中，第一片段在给出停止CPR的指令时开始。之后，第二片段在短短几秒后开始。该实施例中的AED还包括发电电路，其用于为可用于处理可电击心律的除颤脉冲提供电力；以及脉冲传递电路。
根据本发明的一个实施例，提供了一种用于减少在终止心肺复苏和施行除颤电击之间的延迟的自动体外除颤器。AED包括获得与患者的心脏活动相应的ECG信号的ECG传感器以及处理器。处理器运行多个心律分析算法，其中每个算法基于在心肺复苏后具有不同的启动时间的所述ECG信号的片段而独立地确定可电击心律的存在以验证可电击心律的存在。
根据本发明的另一个实施例包括一种用自动体外除颤器传递除颤电击的方法。该方法包括在心肺复苏(CPR)期间给AED充电；用AED的提示装置提示在CPR的中断；以及用第一算法分析在CPR后立即收到的患者的ECG数据的第一片段以确定ECG数据是否具有初始可电击分类。该方法还包括在初始可电击分类后用第一算法监控ECG数据以验证可电击分类保持一致。该方法还包括在第一算法分析和监控ECG数据以获得独立的心律分类的同时，以第二验证算法分析相对于ECG数据的第一片段具有延迟启动时间的ECG数据的第二片段。该方法还包括使用第二算法的心律分类与第一算法的分类进行比较以提供复苏建议的步骤。
另一个实施例包括一种用AED减少在终止心肺复苏和施行除颤电击之间的延迟的方法。这种方法包括发起CPR、给AED充电、提示CPR的中断以及用第一算法分析在CPR后立即收到的第一组ECG数据以确定ECG数据是否具有可电击心律分类的步骤。该方法还包括分析相对于ECG数据的第一组具有延迟启动而获得的第二组ECG数据以确定ECG数据是否具有可电击心律分类以及将第一组ECG数据的分类与第二组ECG数据进行比较以确定是否应通过AED传递除颤电击的步骤。
附图说明
可通过考虑本发明的各实施例的下列详细描述并结合附图更完全地理解本发明，其中：
图1大致示出根据本发明的一个实施例的用CPR和AED治疗心脏骤停受害者的一个实例。
图2大致示出根据本发明的一个实施例的AED硬件的示意图的一个实例。
图3大概示出根据本发明的一个实施例的AED心律分析的操作步骤的流程图。
图4大致示出说明心律评估和AED操作的实例时间线的图，其具有在基本并行运行的算法中的心律评估的成功匹配。
图5大致示出说明心律评估和AED操作的实例时间线的图，其不包括基本并行算法中的心律评估的成功匹配。
具体实施方式
本发明可在不脱离其的本质属性的前提下以其他具体形式实施，因此，所示的实施例应在所有方面中被认为是说明性的而非限制性的。
在本发明的各实施例中，公开了一种装置和方法以快速和可靠地评价从患者获得的ECG信号，从而可使在CRP和传递除颤电击之间的延迟最小化。图1示出正在经历复苏尝试并正接受AED和CPR治疗的心脏骤停的受害者。
所示的AED 100具有被联接至患者胸部的电极片104和106，且所示的救助者108位于能快速对患者110提供胸外按压的位置中。
AHA当前建议所有的救助者(无论是否接受过训练)都应对所有心脏骤停的受害者提供胸外按压，且胸外按压应是对所有的受害者(不论其年龄如何)的最初采取的CPR行动。通常，CPR通过在心脏和大脑中提供关键的血液循环而提高受害者的存活机会。
通常，单独使用CPR将不足以逆转患者的心跳骤停的情况。在这些情况下，AED 100可用于将高振幅电流的脉冲传递至患者的心脏以将其恢复至正常的心律。然而，有许多不同类型的心律，且其中仅有一些被认为是可电击的。主要的可电击心律为心室颤动(VF)、室性心动过速(VT)和心室扑动。非可电击心律可包括心动过缓、电机械分离、室性自主心律和正常的心律。
为了确定心律是否为可电击的，AED分析ECG数据以对患者正在经历的心律的类型进行分类。特别地，一对AED电极104和106位于患者的胸部上，如在图1中所示以获得ECG信号。接下来，通过AED分析ECG信号且如果心律被认为是可电击的，则将除颤脉冲传递至患者。
依赖于ECG分析的AED可被认为是半自动的或全自动的。通常，半自动除颤器要求用户按下按钮以传递实际的除颤电击，相比较，全自动除颤器能在不具有用户的这种输入的情况下传递治疗。本发明的各实施例能用自动和/或半自动AED工作。
在图1中，所示的AED 100被联接至位于患者胸部110上的一对电极104和106。AED100配备有的中央室，其具有铰链盖112以当不使用除颤器时容纳电极片104和106。所示的盖112处于图1中的开放配置中且因此已准备开始使用。在一个实施例中，打开这个盖112启动AED 100并开始将提示发送至用户。提示可包括源自扬声器114的语音提示以及源自显示器116的视觉提示。
图2大致示出根据本发明的一个实施例、实施改进的电击算法的AED 200的硬件的方框图。基于数字微处理器的控制系统202用于控制AED 200的整体操作。电气控制系统202还包括用于测试电极204和206的互联性和可操作性的阻抗测量电路。控制系统202包括接口连接至程序存储器210、数据存储器212、事件存储器214和实时时钟216的处理器208。通过处理器208执行的操作程序被存储在程序存储器210中。电力是通过电池218提供的且被连接至发电电路220。
发电电路220还被连接至功率控制单元222、盖开关224、看门狗定时器226、实时时钟216和处理器208。数据通信端口228被联接至处理器208以进行数据传输。在某些实施例中，可利用串行端口、usb端口、火线、无线，如802.11x或3G、无线电等进行数据传输。救援开关230、维护指示器232、诊断显示面板234、语音电路236和声音报警238也被连接至处理器208。语音电路236被连接至扬声器240。在各种实施例中，救援开关灯242和视觉显示器244被连接至处理器208以提供额外的操作信息。
在某些实施例中，AED将具有处理器208和协处理器246。协处理器246可以是在硬件中实施的心律分析算法并通过高速数据总线被可操作性地连接至处理器。在各种实施例中，处理器208和协处理器246在相同的硅片上且可在多核处理器中予以实施。可替代地，处理器208和协处理器可被实现为多处理器甚或联网处理器布置的一部分。在这些实施例中，处理器208将计算中的一些卸至协处理器，从而优化对从电极204和206感测的信号的处理。在其他实施例中，用具体的指令或用于执行计算的优化对处理器208进行优化。因此，处理器208可在更少的时钟周期内执行计算且同时命令更少的硬件资源。在其他的实施例中，控制系统202的逻辑和算法可在逻辑、以ASIC为形式的硬件或以FPGA为形式的组合等中实施。
高电压生成电路248也被连接至处理器208且通过处理器208进行控制。高电压生成电路248可含有半导体开关(未示出)以及多个电容器(未示出)。在各种实施例中，连接器250和252将高电压生成电路248连接至电极204和206。要注意的是，这里的高电压电路是通过电池提供电力的且具有高功率。
阻抗测量电路254被连接至连接器250和实时时钟216。阻抗测量电路254通过模拟-数字(A/D)转换器256被连接至实时时钟。另一个阻抗测量电路258可被连接至连接器250和实时时钟216且通过模拟-数字(A/D)转换器256被连接至处理器208。可选地，CPR装置260可通过连接器252和A/D转换器256而被连接至处理器208和实时时钟216。CPR装置260可以是胸外按压检测装置或手动、自动或半自动机械胸外按压装置。一些AED设计的额外详细的讨论可在美国专利公开号2011/0105930和美国专利号5474574、5645571、5749902、5792190、5797969、5919212、5999493、6083246、6246907、6263238、6289243、6658290和6993386中找到，其中的每一个均以引用方式并入本文。
通过本发明的实施例所利用的方法和系统一般是由心律分析算法300和301的两个实例所组成，两个算法平行操作以在AED或类似的心肺复苏装置(例如，与在图2中所示的相类似的装置)中进行评估和验证，从而改善用于传递治疗的时间。第一心律分析算法300从接收到AED停止CPR的指令后立即以很少的释抑期或不具有释抑期的方式运行。第二算法为验证算法以及默认的治疗推荐算法。第二心律分析验证算法301在延迟启动后运行以作为验证算法。具体地，第二心律分析验证算法301在被设计为减少CPR伪影对心律分析的影响的释抑期后开始运行。如果在初始学习期后，心律分析300的第一实例指示相同的可电击心律自始自终存在且源自第二心律分析验证算法301的心律分类与源自第一心律分析算法300的第一分类相一致时，除颤器则将建议电击。如果心律分类不匹配，第二心律分类验证算法301则被允许完成整个分析和监控期，且第二算法301所产生的分类被用于确定分类以及用于救援的任何后续协议建议。
图3表明了更详细的流程图，其描述了利用心律分析的AED的操作步骤，该心律分析协调针对具有不同启动点的片段的两个算法以分析ECG信号，从而快速得到心律分类并验证可电击状态的评估。
具体地，采用心律分类算法的一个实施例的AED 100的操作为首先在CPR期间用内部电池给AED电容器充电，如数字302所示。该充电可通过各种方式进行触发。在一些实施例中，充电可简单地通过打开其盖子、将其接通或以其他类似的方法启动AED 100的方式而发生。在其他优选实施例中，只有之前的分析已发现可电击心律时才会发生充电，从而不会以实质性的方式因预充电等对电池的使用寿命产生负面影响。接下来，在CPR期间的合适的点上，AED 100提供表示用户108应停止CPR的语音提示，如数字304所示。紧接着语音提示后为瞬时分析的释抑期或一点也没提供释抑期，如306所表示的。在各种实施例中，该初步分析释抑期仅持续约一秒钟。接下来，第一(或一级)心律分析算法(RAA)引擎(第一心律分析算法300引擎)在308开始并在310进行分析。在一些实施例中，用于该算法的分析期可能会持续约4秒钟。第一心律分析算法300在分析期后进行在312的操作，其中达到可电击决策并在很短的时间内对其进行监控。在一些实施例中，该可电击决策和监控阶段持续大约5秒钟。如果在整个监控阶段保持可电击心律的一致分类，则在314进行确定。在进行第一心律分析算法300的同时，第二心律分析验证算法301以平行评估ECG心律数据的方式同时运行。该第二(或二级)心律分析验证算法301开始于随第一心律分析操作310开始而开始的分析释抑期316。接下来，第二心律分析验证算法301在318即释抑期完成时开始。通过延迟启动第二心律分析验证算法301，可能影响信号完整性的数据伪影和干扰或获得干净信号的能力被大大降低，但这并不依赖于对ECG信号的任何过滤。第二心律分析算法301然后进入分析阶段320。例如，在一些实施例中，该分析期320可持续5秒钟。在该期间的最后，在322作出判断该心律为可电击的还是不可电击的。
接下来，如果第二算法301认为心律是可电击的且第一算法300给出在整个监控期指示可电击心律的一致分类，则在步骤324中发出电击。当在整个监控期的第一算法300不是一致地被分类为可电击的或第二算法301分类不是可电击的，第二算法分类则在326继续进行。然后，在328的整个连续的监控和分析期将第二算法分类为可电击的或不可电击的。如果分类为可电击的，则在330发出除颤电击。如果心律未被分类为可电击的，则在332不传递电击且提供进一步的CPR或救援协议提示或建议。
为了本发明的目的，在各种实施例中，第一心律分析算法也可被理解为一级的心律分析算法且第二心律分析验证算法也可被理解为二级心律分析算法或第二心律分析算法。在某些实施例中，心律分析算法中的每一个可被理解为心脏科学公司的软件算法的修改版本。要注意的是，在各种实施例中，该方法可利用在当前AED中现有的心律分析算法或为用于控制AED操作的完全更新的算法的一部分。
与过去的现有技术相比，使用两个独立的心律分析算法以用于可电击评估和验证的过程为有用的和有利的替代。例如，替代的窗口化技术已被用于整个现有技术中，其限制治疗的决策为进一步进行投票过程以加强一致性的相邻窗口的评估。在其他发明中已对该窗口技术稍做修改以使用数据的重叠窗口加快该评估。一种对重叠的窗口进行建模且已知使用几十年的一种信号分析技术被称之为Welch方法，然而其他类似的技术也是存在的。Welch方法主要是使用谱密度估计教导减少噪声信号，如ECG信号。该方法是基于使用作为将信号从时域转换为频域的结果的周期图频谱估计的概念。基本上，信号被分成窗口化的重叠段且使用傅立叶变换操作以提供对频点的功率测量数组。在Welch方法中的该重叠被认为是有用的，这是因为其减少了在窗口之间的边界上的问题但却提供了用于处理加速心律评估的问题并具体地处理有问题的CPR后的信号的不同的计算方法。见美国专利号7,463,922。
本专利未使用这种窗口化技术，反而使用有针对性的评估和验证过程以不同的方式处理该问题。已发现使用当前公开的利用两个完全独立的算法和验证过程的非窗口化的过程允许来更快地评估和验证电击评估。在本申请中所讨论的方法均利用了紧随在CPR之后的期间且还考虑了在该期间中潜在的噪声不准确性，其方式为过去的技术窗口化数据所未考虑的的方式。
图4示出了在替代的时间线格式中的心律分析过程。具体地，图4为说明心律评估和AED操作的实例时间线的图400，该图在大致平行的心律分析算法300和心律分析验证算法301中的心律评估初步匹配。在该实例中，分析ECG信号并在CPR的十秒内传递除颤电击。
第一时间线部分402表示在进行CPR的同时发生的进行充电的十秒时间。第一时间线片段402的结束对应于在404发生的AED的语音提示的开始。在404的该语音提示指导救助者停止CPR且不要触碰受害者。具体地，语音提示表示“不要触碰患者！分析心律。”
停止CPR的提示也与第一心律分析算法300所进行的分析期406的开始相重合。该分析期406可持续5秒，如在图中所示，或持续另外合适的替代时期。该分析期406的第一秒可包括简短的释抑期，如在一些实施例中的一秒延迟。在分析期406内，获得ECG数据并相对于出现的心脏活动数据的可电击性进行分析。紧随其后的是分析和监控期408。该期间开始于ECG数据的心脏状况的评估，其表示存在有可电击或不可电击的心律。然后，在该期间408内继续对该评估进行分析和监控，从而确保在整个该期间内进行了一致的可电击或不可电击的评估。
在该分析期406发生的同时，第二心律分析验证算法301进行初始的释抑期410。例如，在一些实施例中，该释抑期410可持续4至5秒。释抑期410是有用的，这是因为其避免在CPR后立即收到的信号以及任何潜在的数据伪影和干扰对信号完整性的影响或对获得干净信号的能力的影响。在一些实施例中，释抑期410可在很短的学习期间412内结束，其中获得了ECG数据。一旦释抑期410结束，则在分析期414内通过第二心律分析验证算法301评估所获得的ECG数据以确定可电击或不可电击的心律是否存在。在分析期414内的很短时间后(在一些实施例中为5秒)，与在同时期408内通过第一心律分析算法300所做出的和监控的判断相比，做出可电击心律的判断。
图4示出在分析和监控期408内分类为“可电击”且在分析期414的第一秒后评估也是“可电击”的一种实例。由于这些分类是匹配的，用于传递电击的指令是通过AED控制电路立即提供的。因此，则可能做出这种快速的电击决定，这是因为该方法增加了可在CPR后很快确定的早期心律分类中的置信度。
图5为说明心律评估和AED操作的实例时间线的图500，该图不包括对在平行的算法中的心律评估的初始匹配。在这里，期间508不保持一致的“可电击”分类或第二心律分析验证算法301显示不可电击的心律。在这种情况下，心律分析算法301完成分析期514并基于仅通过心律分析算法301判断的分类而请求治疗。
在图4和5中描绘了另一组原自AED的语音提示。这些进一步的语音提示紧接在404的给出不触碰患者的指令后发生。具体地，接下来的语音提示416将宣布“准备电击。请离开患者！”
相对于电池充电，该充电被设计成由与分析和释抑期406、408、410、412和414部分共有的期间418内继续。然而，电池充电时间短的足以在做出早期电击决策之前为传递除颤脉冲做好准备。在一些实施例中，快充电池也是可能的，其可在比图4和5所示的短的多的时间内完成充电。
还应理解的是，示例性实施例或示例性实施例仅是实例且并不旨在以任何方式限制本发明的范围、适用性或配置。相反地，前面的详细描述将使本领域的技术人员了解本发明以实施(多个)示例性实施例。应理解的是，在不脱离如在所附权利要求和其法律等同物中设置的本发明的范围的前提下可对元件的功能和布置进行各种变化。
上面的实施例均是说明性的而非限制性的。额外的实施例均在权利要求中。虽然已参照特定实施例描述了本发明，但本领域的技术人员将认识到可在不脱离本发明的精神和范围的前提下在形式和细节上进行改变。
在阅读本发明后，对于本领域的技术人员来说，本发明的各种修改可变得显而易见。例如，在相关领域中的普通技术人员将认识到，在本发明的精神内，所描述的用于本发明的不同实施例的各种特性可适当地进行组合、取消组合并单独或以不同的组合方式与其他特性再组合。同样地，上述各种特性应全部被认为是实例实施例而不是用于限制本发明的范围或精神。因此，上述内容不得被考虑为用于限制本发明的范围。
为了解释本发明的权利要求，其明确的意图是除非在权利要求中引用了具体的术语“用于……的方式”或“用于……的步骤”外，均不会调用美国法典第35编的第六段第112条的规定。

Claims (13)

1.一种自动体外除颤器，其包括：
ECG传感器，其获得与患者的心脏活动相对应的ECG信号；
提示装置，其提供心肺复苏(CPR)指令；
控制系统，其包括微处理器，所述微处理器被编程用于在终止CPR的指令后运行两个心律分析算法，所述两个心律分析算法分析所述ECG信号的片段以判断可电击心律的存在，且所述两个心律分析算法中的一个提供延迟启动的可电击心律验证算法；以及
治疗生成电路，其用于响应于判断可电击心律的存在的所述控制系统而用除颤脉冲处理所述可电击心律。
2.根据权利要求1所述的自动体外除颤器，其中所述两个心律分析算法中的第一个包括分析在所述提示装置给出停止CPR的通知后立即接收到的所述ECG信号。
3.根据权利要求2所述的自动体外除颤器，其中所述心律分析算法中的第二个为延迟启动的可电击心律验证算法且包括分析在所述提示装置给出停止CPR的所述通知后有数秒延迟后获得的ECG信号。
4.根据权利要求1所述的自动体外除颤器，其中所述ECG传感器包括一对电极。
5.根据权利要求1所述的自动体外除颤器，其中所述心律分析算法为基本上相同的算法。
6.一种自动体外除颤器，其包括：
ECG传感器，其获得与患者的心脏活动相对应的ECG信号；
提示装置，其用于提供CPR指令；
控制系统，其包括微处理器，所述微处理器适于使用第一算法在所述ECG信号的第一片段中判断可电击心律的存在且使用第二验证算法在所述ECG信号的第二片段中判断可电击心律的存在，其中所述第一算法和所述第二验证算法平行运行并分析所述ECG信号的至少一些共同的片段，且其中所述第一片段在给出停止CPR的指令时开始，所述第二片段在所述第一片段开始后的短短几秒后开始；以及
发电电路，其提供除颤脉冲，所述除颤脉冲被选择性用于当所述控制系统判断可电击心律的存在时处理所述可电击心律；以及
脉冲传递电路，其传递所述除颤脉冲。
7.根据权利要求6所述的自动体外除颤器，其中所述ECG传感器包括一对电极。
8.根据权利要求6所述的自动体外除颤器，其中所述提示装置提供语音提示。
9.根据权利要求6所述的自动体外除颤器，其中配备所述自动体外除颤器以在判断可电击心律存在的情况下，在收到停止CPR的所述自动体外除颤器的指令后少于10秒的时间内提供一次除颤电击。
10.一种自动体外除颤器，适于减少在终止心肺复苏和施行除颤电击之间的延迟，其包括：
ECG传感器，其获得与患者的心脏活动相对应的ECG信号；
处理器，其运行多个心律分析算法，其中每个算法在心肺复苏后以不同的启动时间基于所述ECG信号的片段而独立地确定可电击心律的存在以验证可电击心律的存在。
11.根据权利要求10所述的自动体外除颤器，其中所述心律分析算法中的一个包括分析在提示装置给出停止CPR的通知后立即接收到的所述ECG信号。
12.根据权利要求11所述的自动体外除颤器，其中所述心律分析算法中的不同的一个为延迟启动的验证算法且包括分析在所述提示装置给出停止CPR的所述通知后的数秒延迟后获得的ECG信号。
13.根据权利要求11所述的自动体外除颤器，其中所述ECG传感器包括一对电极。
CN201280074134.7A 2012-04-20 2012-06-15 使aed更快时间进行电击的方法和装置 Active CN104519950B (zh)

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Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10490308B2 (en) 2013-02-20 2019-11-26 Physio-Control, Inc. Context-sensitive chest compression fraction measurement for CPR quality assessment
US10420702B2 (en) 2013-02-20 2019-09-24 Physio-Control, Inc. CPR quality assessment accounting for pause aspect
EP2815749A1 (en) 2013-06-20 2014-12-24 IP Gesellschaft für Management mbH Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern
US10076670B2 (en) * 2014-01-02 2018-09-18 Koninklijke Philips N.V. Consistency monitoring for ECG shock advisory decisions
US9808640B2 (en) * 2014-04-10 2017-11-07 Medtronic, Inc. Method and apparatus for discriminating tachycardia events in a medical device using two sensing vectors
EP3229895B8 (en) * 2014-12-12 2020-04-01 Koninklijke Philips N.V. Analyze option button for an automated external defibrillator (aed) with dual ecg analysis algorithms
JP6776239B2 (ja) 2014-12-12 2020-10-28 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． デュアルｅｃｇ解析アルゴリズムを用いた自動体外式除細動器（ａｅｄ）
JP6464267B2 (ja) * 2014-12-12 2019-02-06 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 二つのｅｃｇ解析アルゴリズムを備えた自動体外式除細動器（ａｅｄ）のための信頼度解析器
US10335604B2 (en) 2014-12-18 2019-07-02 Koninklijke Philips N.V. Apparatus for monitoring a cardiac rhythm during CPR
JP6633635B2 (ja) * 2014-12-18 2020-01-22 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． スケジューリングされた動作モード及び連続的な動作モードを有する除細動器
US11076795B2 (en) 2015-06-30 2021-08-03 Koninklijke Philips N.V. Apparatus for reversing a shock decision in an automated external defibrillator
CN115153574A (zh) * 2016-01-16 2022-10-11 Zoll医疗公司 除颤器
US11058486B2 (en) 2016-02-11 2021-07-13 Covidien Lp Systems and methods for percutaneous microwave ablation
US10894168B2 (en) * 2016-03-30 2021-01-19 Koninklijke Philips N.V. Automated external defibrillator with shortened pause for rhythm analysis
US10940323B2 (en) * 2016-10-04 2021-03-09 West Affum Holdings Corp. Wearable cardioverter defibrillator (WCD) with power-saving function
US11235143B2 (en) 2017-02-03 2022-02-01 West Affum Holdings Corp. Wearable cardiac defibrillator systems and methods and software for contacting non-witnessing responders
US10555679B2 (en) * 2017-06-20 2020-02-11 General Electric Company Non-contact heart rate monitoring
US11179293B2 (en) 2017-07-28 2021-11-23 Stryker Corporation Patient support system with chest compression system and harness assembly with sensor system
WO2020056028A1 (en) 2018-09-14 2020-03-19 Avive Solutions, Inc. Shockable heart rhythm classifier for defibrillators
CN112714663A (zh) * 2018-12-29 2021-04-27 深圳迈瑞生物医疗电子股份有限公司 除颤方法、自动体外除颤仪及计算机可读取介质
CN116801944A (zh) * 2021-12-23 2023-09-22 深圳迈瑞生物医疗电子股份有限公司 用于除颤仪的节律分析和决策方法、装置以及存储介质
US11794025B1 (en) 2022-04-04 2023-10-24 Altrix Medical, Inc. Compact AED with integrated CPR coaching
US11633613B1 (en) 2022-04-04 2023-04-25 Altrix Medical, Inc. Compact AED with external electrocardiogram

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006016289A2 (en) * 2004-08-09 2006-02-16 Koninklijke Philips Electronics, N.V. External defibrillator with pre-cpr-ecg based defibrillating shock
WO2007069162A1 (en) * 2005-12-16 2007-06-21 Koninklijke Philips Electronics, N.V. Automatic external defibrillator with increased cpr administration time

Family Cites Families (337)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2943628A (en) 1957-02-27 1960-07-05 William L Howell Electrode assembly
US3093136A (en) 1960-05-25 1963-06-11 Mine Safety Appliances Co Ventricular defibrillator
BE632412A (zh) 1962-05-17
US3138151A (en) 1962-06-11 1964-06-23 Robert L Chapman Detector and alarm ventricular impulses
US3409007A (en) 1965-11-26 1968-11-05 Lockheed Aircraft Corp Body electrode support garment
DE1282802B (de) 1966-02-09 1968-11-14 Fritz Hellige & Co G M B H Fab Geraet zur elektrischen Stimulierung des Herzens
US3464404A (en) 1966-06-17 1969-09-02 Univ Johns Hopkins Bio-medical instrumentation electrode
US3426746A (en) 1966-10-10 1969-02-11 Seamans Jr Robert C Method and apparatus for attaching physiological monitoring electrodes
US3580243A (en) 1968-10-21 1971-05-25 Marquette Electronics Inc Means and method for subtracting dc noise from electrocardiographic signals
US3569852A (en) 1969-01-23 1971-03-09 American Optical Corp Frequency selective variable gain amplifier
US3703900A (en) 1969-12-02 1972-11-28 Cardiac Resuscitator Corp Cardiac resuscitator
US3606881A (en) 1970-02-20 1971-09-21 Riley D Woodson Conductive rubber electrode
US3654537A (en) 1970-04-29 1972-04-04 Westinghouse Electric Corp High efficiency power supply for charging capacitors in steps
US3727190A (en) 1970-11-09 1973-04-10 Chromalloy American Corp Patient signal dispatcher
US3706313A (en) 1971-02-04 1972-12-19 Medical Research Lab Trapezoidal waveshape defibrillator
US3702613A (en) 1971-03-04 1972-11-14 Health Systems Inc Electrolyte envelope for use on the active surface of a defibrillator paddle
US3942536A (en) 1971-03-15 1976-03-09 Mieczyslaw Mirowski Cardioverting device having single intravascular catheter electrode system and method for its use
US3857398A (en) 1971-12-13 1974-12-31 L Rubin Electrical cardiac defibrillator
US3805795A (en) 1972-03-17 1974-04-23 Medtronic Inc Automatic cardioverting circuit
US3810102A (en) 1972-03-31 1974-05-07 Telserv Inc System for transmission and analysis of biomedical data
US4088138A (en) 1974-01-02 1978-05-09 Cardiac Resuscitator Corp. Cardiac resuscitator and monitoring apparatus
US3826245A (en) 1973-02-09 1974-07-30 Statham Instrument Inc Electrodes employing disposable electropods for cardiac instruments
US3882853A (en) 1973-02-15 1975-05-13 Cardiodynamics Biomedical electrode
JPS5335422B2 (zh) 1973-02-28 1978-09-27
US3903874A (en) 1973-08-27 1975-09-09 Mediscience Technology Corp Cardiographic signal processing means and method
US3886950A (en) 1973-10-01 1975-06-03 Spacelabs Inc Defibrillator
US4058127A (en) 1973-11-15 1977-11-15 Gilbert Buchalter Method of applying viscous fluid to a surface
US4002239A (en) 1973-11-15 1977-01-11 Gilbert Buchalter Cardiac defibrillator cup
US3860009A (en) 1973-11-29 1975-01-14 David Bell Computer controlled defibrillator
US3927663A (en) 1974-05-02 1975-12-23 Phsiological Electronics Corp Method and apparatus for detecting cardiac arrhythmias
US3972320A (en) 1974-08-12 1976-08-03 Gabor Ujhelyi Kalman Patient monitoring system
US3942533A (en) 1974-10-17 1976-03-09 Cannon Robert L Iii Cardiac defibrillator depolarizing paddle arrangement
GB1481469A (en) 1974-10-28 1977-07-27 Anderson J Defibrillator
US3961623A (en) 1975-01-17 1976-06-08 Medical Research Laboratories, Inc. Method of using a disposable electrode pad
US3989036A (en) 1975-04-02 1976-11-02 Dia Medical System Co., Ltd. Biophysical electrode
US3998213A (en) 1975-04-08 1976-12-21 Bio-Volt Corporation Self-adjustable holder for automatically positioning electroencephalographic electrodes
US4202340A (en) 1975-09-30 1980-05-13 Mieczyslaw Mirowski Method and apparatus for monitoring heart activity, detecting abnormalities, and cardioverting a malfunctioning heart
US4096856A (en) 1976-09-03 1978-06-27 Physio-Control Corporation Portable electronic physiological instrument having separable first and second components, and improved mechanical connector therefor
US4129125A (en) 1976-12-27 1978-12-12 Camin Research Corp. Patient monitoring system
US4369284A (en) 1977-03-17 1983-01-18 Applied Elastomerics, Incorporated Thermoplastic elastomer gelatinous compositions
US4618213A (en) 1977-03-17 1986-10-21 Applied Elastomerics, Incorporated Gelatinous elastomeric optical lens, light pipe, comprising a specific block copolymer and an oil plasticizer
US4173971A (en) 1977-08-29 1979-11-13 Karz Allen E Continuous electrocardiogram monitoring method and system for cardiac patients
US4177817A (en) 1978-02-01 1979-12-11 C. R. Bard, Inc. Dual terminal transcutaneous electrode
US4216462A (en) 1978-03-06 1980-08-05 General Electric Company Patient monitoring and data processing system
US4243051A (en) 1979-01-08 1981-01-06 Johnson & Johnson Disposable electrode
US4365634A (en) 1979-12-06 1982-12-28 C. R. Bard, Inc. Medical electrode construction
JPS5933361Y2 (ja) 1980-03-14 1984-09-18 日東電工株式会社 電極パッド
US4296755A (en) 1980-03-19 1981-10-27 Datamedix Inc. Method and apparatus for determining ventricular fibrillation
US4576170A (en) 1980-07-09 1986-03-18 Micro-Circuits Company Heart monitor and defibrillator device
US4494552A (en) 1980-08-08 1985-01-22 R2 Corporation Physiological monitoring electrode system
US4381012A (en) 1980-09-24 1983-04-26 Wallant International Trade, Inc. Electrode placement device
US4408615A (en) 1981-03-02 1983-10-11 Cambridge Instruments, Inc. Interference filter
US4420815A (en) 1981-05-18 1983-12-13 International Business Machines Corporation Apparatus and method for removal of sinusoidal noise from a sampled signal
JPS5843615A (ja) 1981-09-10 1983-03-14 Kureha Chem Ind Co Ltd コンデンサ−出力回路
NL193256C (nl) 1981-11-10 1999-04-02 Cordis Europ Sensorsysteem.
US4523595A (en) 1981-11-25 1985-06-18 Zibell J Scott Method and apparatus for automatic detection and treatment of ventricular fibrillation
US4475208A (en) 1982-01-18 1984-10-02 Ricketts James A Wired spread spectrum data communication system
US4531527A (en) 1982-04-23 1985-07-30 Survival Technology, Inc. Ambulatory monitoring system with real time analysis and telephone transmission
DE3229134A1 (de) 1982-08-04 1984-02-09 GS Elektromed. Geräte Günter Stemple, 8912 Kaufering Elektrische schaltung zur erzeugung von energieimpulsen an zwei schockelektroden eines defibrillators
US4494551A (en) 1982-11-12 1985-01-22 Medicomp, Inc. Alterable frequency response electrocardiographic amplifier
US4729377A (en) 1983-06-01 1988-03-08 Bio-Stimu Trend Corporation Garment apparatus for delivering or receiving electric impulses
US4537200A (en) 1983-07-07 1985-08-27 The Board Of Trustees Of The Leland Stanford Junior University ECG enhancement by adaptive cancellation of electrosurgical interference
US4619265A (en) 1984-03-08 1986-10-28 Physio-Control Corporation Interactive portable defibrillator including ECG detection circuit
US4610254A (en) 1984-03-08 1986-09-09 Physio-Control Corporation Interactive portable defibrillator
US6075342A (en) 1989-12-05 2000-06-13 Intermec Ip Corp. Fast battery charging system and method
US4574810A (en) 1984-10-05 1986-03-11 Lerman Bruce B Automatic threshold defibrillator
US4637397A (en) 1985-05-30 1987-01-20 Case Western Reserve University Triphasic wave defibrillation
US5179569A (en) 1985-07-19 1993-01-12 Clinicom, Incorporated Spread spectrum radio communication system
US4835372A (en) 1985-07-19 1989-05-30 Clincom Incorporated Patient care system
US5002064A (en) 1985-08-09 1991-03-26 Allain Joseph L Portable life detection monitor including lead fail detector and unique signal processing system
US4724435A (en) 1985-11-06 1988-02-09 Applied Spectrum Technologies, Inc. Bi-directional data telemetry system
US4745923A (en) 1985-11-20 1988-05-24 Intermedics, Inc. Protection apparatus for patient-implantable device
US4763660A (en) 1985-12-10 1988-08-16 Cherne Industries, Inc. Flexible and disposable electrode belt device
US4800883A (en) 1986-04-02 1989-01-31 Intermedics, Inc. Apparatus for generating multiphasic defibrillation pulse waveform
US4850009A (en) 1986-05-12 1989-07-18 Clinicom Incorporated Portable handheld terminal including optical bar code reader and electromagnetic transceiver means for interactive wireless communication with a base communications station
US4768512A (en) 1986-05-13 1988-09-06 Mieczyslaw Mirowski Cardioverting system and method with high-frequency pulse delivery
US4796620A (en) 1986-05-13 1989-01-10 Mieczyslaw Mirowski System for sensing abnormal heart activity by means of heart rate acceleration and deceleration detection
US5014697A (en) 1986-05-14 1991-05-14 Ventritex Programmable defibrillator
US4803625A (en) 1986-06-30 1989-02-07 Buddy Systems, Inc. Personal health monitor
US4802491A (en) 1986-07-30 1989-02-07 Massachusetts Institute Of Technology Method and apparatus for assessing myocardial electrical stability
US4860758A (en) 1986-08-14 1989-08-29 Olympus Optical Co. Ltd. Multiple diagnosable distance range ultrasonic diagnostic apparatus
US4732157A (en) 1986-08-18 1988-03-22 Massachusetts Institute Of Technology Method and apparatus for quantifying beat-to-beat variability in physiologic waveforms
US4784162A (en) 1986-09-23 1988-11-15 Advanced Medical Technologies Portable, multi-channel, physiological data monitoring system
US4827943A (en) 1986-09-23 1989-05-09 Advanced Medical Technologies, Inc. Portable, multi-channel, physiological data monitoring system
US4889132A (en) 1986-09-26 1989-12-26 The University Of North Carolina At Chapel Hill Portable automated blood pressure monitoring apparatus and method
US4839806A (en) 1986-09-30 1989-06-13 Goldfischer Jerome D Computerized dispensing of medication
US5088489A (en) 1986-10-03 1992-02-18 Lerman Bruce B Current-based defibrillating method
GB8626601D0 (en) 1986-11-07 1986-12-10 Pa Consulting Services Testing apparatus
US4953551A (en) 1987-01-14 1990-09-04 Medtronic, Inc. Method of defibrillating a heart
US4821723A (en) 1987-02-27 1989-04-18 Intermedics Inc. Biphasic waveforms for defibrillation
US4823796A (en) 1987-04-03 1989-04-25 Laerdal Manufacturing Corp. Defibrillator circuit for producing a trapezoidal defibrillation pulse
US4887609A (en) 1987-05-13 1989-12-19 The Methodist Hospital System Apparatus and method for filtering electrocardiograph signals
EP0309627B1 (en) 1987-09-30 1993-06-16 International Business Machines Corporation Apparatus for connecting data processing equipment to a telephone network
US5014698A (en) 1987-10-06 1991-05-14 Leonard Bloom Method of and system for monitoring and treating a malfunctioning heart
US5156148A (en) 1987-10-06 1992-10-20 Leonard Bloom System for treating a malfunctioning heart
GB8726933D0 (en) 1987-11-18 1987-12-23 Cadell T E Telemetry system
US4889131A (en) 1987-12-03 1989-12-26 American Health Products, Inc. Portable belt monitor of physiological functions and sensors therefor
US4909260A (en) 1987-12-03 1990-03-20 American Health Products, Inc. Portable belt monitor of physiological functions and sensors therefor
US4850357A (en) 1988-01-12 1989-07-25 Cardiac Pacemakers, Inc. Biphasic pulse generator for an implantable defibrillator
US5083562A (en) 1988-01-19 1992-01-28 Telectronics Pacing Systems, Inc. Method and apparatus for applying asymmetric biphasic truncated exponential countershocks
US4966154A (en) 1988-02-04 1990-10-30 Jonni Cooper Multiple parameter monitoring system for hospital patients
US4928690A (en) 1988-04-25 1990-05-29 Lifecor, Inc. Portable device for sensing cardiac function and automatically delivering electrical therapy
US4955381A (en) 1988-08-26 1990-09-11 Cardiotronics, Inc. Multi-pad, multi-function electrode
US4952928A (en) 1988-08-29 1990-08-28 B. I. Incorporated Adaptable electronic monitoring and identification system
US4916441A (en) 1988-09-19 1990-04-10 Clinicom Incorporated Portable handheld terminal
US5042499A (en) 1988-09-30 1991-08-27 Frank Thomas H Noninvasive electrocardiographic method of real time signal processing for obtaining and displaying instantaneous fetal heart rate and fetal heart rate beat-to-beat variability
US5072383A (en) 1988-11-19 1991-12-10 Emtek Health Care Systems, Inc. Medical information system with automatic updating of task list in response to entering orders and charting interventions on associated forms
FR2641093B1 (zh) 1988-12-23 1994-04-29 Alcatel Business Systems
US4911169A (en) 1989-03-13 1990-03-27 Ferrari Robert K Biomedical electrode with limb band
JPH0336328Y2 (zh) 1989-03-30 1991-08-01
US4969465A (en) 1989-05-19 1990-11-13 Ventritex, Inc. Cardiac therapy method
US5050612A (en) 1989-09-12 1991-09-24 Matsumura Kenneth N Device for computer-assisted monitoring of the body
US4996984A (en) 1989-09-26 1991-03-05 Eli Lilly And Company Defibrillation method
US5036462A (en) 1989-09-29 1991-07-30 Healthtech Services Corp. Interactive patient assistance and medication delivery systems responsive to the physical environment of the patient
US5022404A (en) 1989-10-16 1991-06-11 Marquette Electronics. Inc. Cardiac monitoring method and apparatus
US5333617A (en) 1989-10-16 1994-08-02 Marquette Electronics, Inc. Cardiac monitoring method and apparatus
US5010887A (en) 1989-11-17 1991-04-30 Siemens-Pacesetter, Inc. Noise discrimination in implantable pacemakers
CA2022802A1 (en) 1989-12-05 1991-06-06 Steven E. Koenck Fast battery charging system and method
US5025452A (en) 1990-03-20 1991-06-18 Andrew Corporation Full-duplex, sub-band spread spectrum communications system
US4998531A (en) 1990-03-28 1991-03-12 Cardiac Pacemakers, Inc. Implantable N-phasic defibrillator output bridge circuit
US5097830A (en) 1990-03-30 1992-03-24 Laerdal Manufacturing Corporation Defibrillator with reliability verification
US5077753A (en) 1990-04-09 1991-12-31 Proxim, Inc. Radio communication system using spread spectrum techniques
US4995398A (en) 1990-04-30 1991-02-26 Turnidge Patrick A Coronary angiography imaging system
US5171977A (en) 1990-05-14 1992-12-15 Sunquest Information Systems, Inc. Portable medical specimen data collection system
US5111813A (en) 1990-05-18 1992-05-12 Hewlett-Packard Company Defibrillation employing an impedance-corrected delivered energy
US5166952A (en) 1990-05-24 1992-11-24 Cylink Corporation Method and apparatus for the reception and demodulation of spread spectrum radio signals
US5100624A (en) 1990-06-04 1992-03-31 Fmc Corporation Apparatus for determining the stability of a peroxygen
US5036856A (en) 1990-07-19 1991-08-06 Thornton William E Cardiovascular monitoring system
US4993421A (en) 1990-07-20 1991-02-19 Thornton William E Cardiac monitoring system
US5086772A (en) 1990-07-30 1992-02-11 Telectronics Pacing Systems, Inc. Arrhythmia control system employing arrhythmia recognition algorithm
ATE143280T1 (de) 1990-12-18 1996-10-15 Ventritex Inc Gerät zur herstellung konfigurierbarer, zweiphasiger entflimmerungswellenformen
US5108466A (en) 1990-12-21 1992-04-28 Hewlett-Packard Company Apparatus and methods for controlling fluids provided to a chromatographic detector
US5212715A (en) 1991-01-25 1993-05-18 Motorola, Inc. Digital communication signalling system
US5205294A (en) 1991-02-19 1993-04-27 Pacific Communications, Inc. Apparatus and methodology for digital telemetry of biomedical signals
US5842997A (en) 1991-02-20 1998-12-01 Georgetown University Non-invasive, dynamic tracking of cardiac vulnerability by simultaneous analysis of heart rate variability and T-wave alternans
US5437285A (en) 1991-02-20 1995-08-01 Georgetown University Method and apparatus for prediction of sudden cardiac death by simultaneous assessment of autonomic function and cardiac electrical stability
US5148812A (en) 1991-02-20 1992-09-22 Georgetown University Non-invasive dynamic tracking of cardiac vulnerability by analysis of t-wave alternans
US5265617A (en) 1991-02-20 1993-11-30 Georgetown University Methods and means for non-invasive, dynamic tracking of cardiac vulnerability by simultaneous analysis of heart rate variability and T-wave alternans
DE4106858A1 (de) 1991-03-04 1992-09-10 Siemens Ag Anordnung zum herausfiltern von grundlinienschwankungen aus physiologischen messsignalen
US5431686A (en) 1992-02-18 1995-07-11 Angeion Corporation Method for optimal pulse defibrillation using an implantable defibrillator
US5199429A (en) 1991-05-23 1993-04-06 Angemed, Inc. Implantable defibrillator system employing capacitor switching networks
US5179571A (en) 1991-07-10 1993-01-12 Scs Mobilecom, Inc. Spread spectrum cellular handoff apparatus and method
US5230336A (en) 1991-08-16 1993-07-27 Ventritex, Inc. Method and apparatus for impedance based automatic pulse duration adjustment for defibrillation shock delivery
US5269313A (en) 1991-09-09 1993-12-14 Sherwood Medical Company Filter and method for filtering baseline wander
US5259387A (en) 1991-09-09 1993-11-09 Quinton Instrument Company ECG muscle artifact filter system
US5353793A (en) 1991-11-25 1994-10-11 Oishi-Kogyo Company Sensor apparatus
US5411525A (en) 1992-01-30 1995-05-02 Cardiac Pacemakers, Inc. Dual capacitor biphasic defibrillator waveform generator employing selective connection of capacitors for each phase
US5534015A (en) 1992-02-18 1996-07-09 Angeion Corporation Method and apparatus for generating biphasic waveforms in an implantable defibrillator
US5306291A (en) 1992-02-26 1994-04-26 Angeion Corporation Optimal energy steering for an implantable defibrillator
US5318036A (en) 1992-03-17 1994-06-07 Hewlett-Packard Company Method and apparatus for removing baseline wander from an ECG signal
US5385575A (en) 1992-03-24 1995-01-31 Angeion Corporation Implantable cardioverter defibrillator having variable output capacitance
US5411526A (en) 1992-03-24 1995-05-02 Angeion Corporation Improved implantable defibrillator system for producing true-voltage-pulse waveforms
US5474574A (en) 1992-06-24 1995-12-12 Cardiac Science, Inc. Automatic external cardioverter/defibrillator
SE9202666D0 (sv) 1992-09-16 1992-09-16 Siemens Elema Ab Foerfarande och anordning foer att oeka energiuttaget ur kondensatorer
US5402884A (en) 1992-09-24 1995-04-04 Surviva Link Corporation Medical electrode packaging technology
US5207219A (en) 1992-10-23 1993-05-04 Incontrol, Inc. Atrial defibrillator and method for providing interval timing prior to cardioversion
DE69329816T2 (de) 1992-11-19 2001-04-19 Cardiac Pacemakers, Inc. System zur Ladung von Defibrillatorskondensatoren in einer konstanten Zeitperiode und zu deren Entladung
US5342402A (en) 1993-01-29 1994-08-30 Medtronic, Inc. Method and apparatus for detection and treatment of tachycardia and fibrillation
US5405361A (en) 1993-03-15 1995-04-11 Surviva Link Corporation External defibrillator circuit
US5879374A (en) 1993-05-18 1999-03-09 Heartstream, Inc. External defibrillator with automatic self-testing prior to use
US5468254A (en) 1993-07-26 1995-11-21 Cardiac Pacemakers, Inc. Method and apparatus for defibrillation using a multiphasic truncated exponential waveform
US5607454A (en) 1993-08-06 1997-03-04 Heartstream, Inc. Electrotherapy method and apparatus
US5601612A (en) 1993-08-06 1997-02-11 Heartstream, Inc. Method for applying a multiphasic waveform
US5540723A (en) 1993-10-06 1996-07-30 Duke University Method and apparatus for delivering an optimum shock duration in treating cardiac arrhythmias
US5372606A (en) 1993-10-07 1994-12-13 Cardiac Pacemakers, Inc. Method and apparatus for generating adaptive n-phasic defibrillation waveforms
US5462157A (en) 1993-10-28 1995-10-31 Zmd Corporation Electrode package
US5381798A (en) 1993-11-02 1995-01-17 Quinton Instrument Company Spread spectrum telemetry of physiological signals
US5391186A (en) 1993-12-13 1995-02-21 Angeion Corporation Method and apparatus for utilizing short tau capacitors in an implantable cardioverter defibrillator
US5713367A (en) 1994-01-26 1998-02-03 Cambridge Heart, Inc. Measuring and assessing cardiac electrical stability
US5570696A (en) 1994-01-26 1996-11-05 Cambridge Heart, Inc. Method and apparatus for assessing myocardial electrical stability
US5391187A (en) 1994-02-22 1995-02-21 Zmd Corporation Semiautomatic defibrillator with heart rate alarm driven by shock advisory algorithm
US5496349A (en) 1994-03-11 1996-03-05 Physio-Control Corporation Method and system for automatic or semi-automatic defilbrillation using redundant processing
US5447519A (en) 1994-03-19 1995-09-05 Medtronic, Inc. Method and apparatus for discrimination of monomorphic and polymorphic arrhythmias and for treatment thereof
US7930782B2 (en) 1994-04-19 2011-04-26 Applied Elastomerics, Inc. Gels, gel composites, and gel articles
US7661164B2 (en) 1997-05-27 2010-02-16 Applied Elastomerics, Inc. Collapsible gel articles
US6185457B1 (en) 1994-05-31 2001-02-06 Galvani, Ltd. Method and apparatus for electrically forcing cardiac output in an arrhythmia patient
US5470343A (en) 1994-06-10 1995-11-28 Zmd Corporation Detachable power supply for supplying external power to a portable defibrillator
US5529686A (en) 1994-07-15 1996-06-25 Minnesota Mining And Manufacturing Company Composite membranes for solid phase extractions and reactions
US5683424A (en) 1994-08-30 1997-11-04 The Ohio State University Research Foundation Non-invasive monitoring and treatment of subjects in cardiac arrest using ECG parameters predictive of outcome
US5571142A (en) 1994-08-30 1996-11-05 The Ohio State University Research Foundation Non-invasive monitoring and treatment of subjects in cardiac arrest using ECG parameters predictive of outcome
US5935082A (en) 1995-01-26 1999-08-10 Cambridge Heart, Inc. Assessing cardiac electrical stability
US5555888A (en) 1995-02-27 1996-09-17 Brewer; James E. Method for automatic, adaptive, active facilitation to access myocardial electrical instability
JP4151766B2 (ja) 1995-03-03 2008-09-17 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 差動信号検出器において同相モード信号を用いてアーティファクトを検出する方法および装置
US5545186A (en) 1995-03-30 1996-08-13 Medtronic, Inc. Prioritized rule based method and apparatus for diagnosis and treatment of arrhythmias
US5697958A (en) 1995-06-07 1997-12-16 Intermedics, Inc. Electromagnetic noise detector for implantable medical devices
US5620465A (en) 1995-06-08 1997-04-15 Survivalink Corporation External defibrillator for producing and testing biphasic waveforms
US5645571B1 (en) 1995-08-01 1999-08-24 Surviva Link Corp Automated external defibrillator with lid activated self-test system
US5797969A (en) 1995-08-01 1998-08-25 Survivalink Corporation One button lid activated automatic external defibrillator
US5558098A (en) 1995-11-02 1996-09-24 Ventritex, Inc. Method and apparatus for detecting lead sensing artifacts in cardiac electrograms
US5762068A (en) 1995-11-27 1998-06-09 Quinton Instrument Company ECG filter and slew rate limiter for filtering an ECG signal
US5687735A (en) 1996-03-28 1997-11-18 Hewlett-Packard Company Robust time-diversity filter and method for removing electromagnetic interference
US5700281A (en) 1996-06-04 1997-12-23 Survivalink Corporation Stage and state monitoring automated external defibrillator
US5697955A (en) 1996-05-10 1997-12-16 Survivalink Corporation Defibrillator electrodes and date code detector circuit
US5817151A (en) 1996-06-04 1998-10-06 Survivalink Corporation Circuit detectable packaged medical electrodes
US5999493A (en) 1996-05-13 1999-12-07 Survivalink Corporation Synchronization method and apparatus for isolated clock system
US5836993A (en) 1996-05-16 1998-11-17 Heartstream, Inc. Electrotherapy device control system and method
US5749902A (en) 1996-05-22 1998-05-12 Survivalink Corporation Recorded data correction method and apparatus for isolated clock systems
US6101413A (en) 1996-06-04 2000-08-08 Survivalink Corporation Circuit detectable pediatric defibrillation electrodes
US5773961A (en) 1996-06-06 1998-06-30 Heartstream, Inc. Dynamic load controller for a battery
US5991658A (en) 1996-07-01 1999-11-23 Survivalink Corporation Continual waveform shape reforming method and apparatus for transchest resistance dynamics
US5803084A (en) 1996-12-05 1998-09-08 Olson; Charles Three dimensional vector cardiographic display and method for displaying same
US5733310A (en) 1996-12-18 1998-03-31 Zmd Corporation Electrotherapy circuit and method for producing therapeutic discharge waveform immediately following sensing pulse
US5792065A (en) 1997-03-18 1998-08-11 Marquette Medical Systems, Inc. Method and apparatus for determining T-wave marker points during QT dispersion analysis
US6029085A (en) 1997-04-09 2000-02-22 Survivalink Corporation Charging and safety control for automated external defibrillator and method
US5978707A (en) 1997-04-30 1999-11-02 Cardiac Pacemakers, Inc. Apparatus and method for treating ventricular tachyarrhythmias
US5827195A (en) 1997-05-09 1998-10-27 Cambridge Heart, Inc. Electrocardiogram noise reduction using multi-dimensional filtering
US5817132A (en) 1997-05-09 1998-10-06 Cedars-Sinai Medical Center Defibrillation apparatus and method
US5999845A (en) 1997-05-21 1999-12-07 Quinton Instrument Company Muscle artifact noise detector for ECG signals
EP0948374B1 (en) 1997-11-06 2005-03-16 Koninklijke Philips Electronics N.V. External defibrillator with cpr prompts and acls prompts
US6169387B1 (en) 1997-12-22 2001-01-02 Lifecor, Inc. Battery management apparatus for portable electronic devices
US6005370A (en) 1998-01-26 1999-12-21 Physio-Control Manufacturing Corporation Automatic rate control for defibrillator capacitor charging
US5871509A (en) 1998-04-02 1999-02-16 Pacesetter Ab Method and apparatus to remove data outliers, produced by external disturbance, in internally measured signals in an implantable cardiac stimulator
US6083246A (en) 1998-04-08 2000-07-04 Survivalink Corporation Lid open detection circuit for automated external defibrillators
US6263238B1 (en) 1998-04-16 2001-07-17 Survivalink Corporation Automatic external defibrillator having a ventricular fibrillation detector
EA200001257A1 (ru) 1998-06-09 2001-08-27 ФАРНОУ ТЕКНОЛОДЖИЗ ПиТиВай. ЛТД. Система аккумулирования энергии
US6108578A (en) 1998-09-02 2000-08-22 Heartstream, Inc. Configurable arrhythmia analysis algorithm
US5957856A (en) 1998-09-25 1999-09-28 Institute Of Critical Care Medicine Method and system for predicting the immediate success of a defibrillatory shock during cardiac arrest
US6370423B1 (en) 1998-10-05 2002-04-09 Juan R. Guerrero Method for analysis of biological voltage signals
US6125299A (en) 1998-10-29 2000-09-26 Survivalink Corporation AED with force sensor
US6409659B1 (en) 1998-11-04 2002-06-25 Ge Medical Systems Information Technologies, Inc. Method and apparatus for displaying physiological patient data
US6390996B1 (en) 1998-11-09 2002-05-21 The Johns Hopkins University CPR chest compression monitor
US6334070B1 (en) 1998-11-20 2001-12-25 Medtronic Physio-Control Manufacturing Corp. Visual and aural user interface for an automated external defibrillator
NO310137B1 (no) 1998-12-11 2001-05-28 Laerdal Medical As System for å måle og analysere HLR parametere for anvendelse med og av en ekstern defibrillator
US6243604B1 (en) 1999-02-26 2001-06-05 Medical Research Laboratories, Inc. Apparatus for charging defibrillator capacitors
US6292692B1 (en) 1999-04-30 2001-09-18 Medical Research Laboratories, Inc. Medical treatment device with functions, operated under passcode control
US6169919B1 (en) 1999-05-06 2001-01-02 Beth Israel Deaconess Medical Center, Inc. System and method for quantifying alternation in an electrocardiogram signal
US6298266B1 (en) 1999-08-10 2001-10-02 Intermedics Inc. Methods and apparatus for treating fibrillation and creating defibrillation waveforms
NO311746B1 (no) 1999-08-27 2002-01-21 Laerdal Medical As System for å redusere signalforstyrrelser i EKG forårsaket av hjerte-lunge-redning
US6735466B1 (en) 1999-09-29 2004-05-11 Cambridge Heart, Inc. Analytical signal method for analysis of T-wave alternans
US6440082B1 (en) 1999-09-30 2002-08-27 Medtronic Physio-Control Manufacturing Corp. Method and apparatus for using heart sounds to determine the presence of a pulse
US20030109790A1 (en) 2001-12-06 2003-06-12 Medtronic Physio-Control Manufacturing Corp. Pulse detection method and apparatus using patient impedance
US7027863B1 (en) 1999-10-25 2006-04-11 Impulse Dynamics N.V. Device for cardiac therapy
US7085601B1 (en) 1999-11-17 2006-08-01 Koninklijke Philips Electronics N.V. External atrial defibrillator and method for personal termination of atrial fibrillation
US6246907B1 (en) 1999-12-01 2001-06-12 Cardiacscience, Inc. Automatic external cardioverter/defibrillator with cardiac rate detector and method of operating the same
US6289243B1 (en) 1999-12-01 2001-09-11 Cardiac Science, Inc. Automatic external cardioverter/defibrillator with tachyarrhythmia detector using a modulation (amplitude and frequency) domain function
US6647290B2 (en) 2000-01-18 2003-11-11 Koninklijke Philips Electronics N.V. Charge-based defibrillation method and apparatus
US6885888B2 (en) 2000-01-20 2005-04-26 The Cleveland Clinic Foundation Electrical stimulation of the sympathetic nerve chain
US6356786B1 (en) 2000-01-20 2002-03-12 Electrocore Techniques, Llc Method of treating palmar hyperhydrosis by electrical stimulation of the sympathetic nervous chain
US7164945B2 (en) 2001-09-14 2007-01-16 Zoll Medical Corporation Defibrillators
JP2003521355A (ja) 2000-02-04 2003-07-15 ゼットエムデー コーポレイション 統合された救急蘇生法
US6453191B2 (en) 2000-02-18 2002-09-17 Cambridge Heart, Inc. Automated interpretation of T-wave alternans results
US6823213B1 (en) 2000-04-28 2004-11-23 Medtronic, Inc. Implantable medical device and method using integrated T-wave alternans analyzer
US6658290B1 (en) 2000-06-12 2003-12-02 Cardiac Science, Inc. Public access defibrillator
US6694187B1 (en) 2000-06-23 2004-02-17 Koninklijke Philips Electronics N.V. External defibrillator instruction system and method
US6480734B1 (en) 2000-06-30 2002-11-12 Cardiac Science Inc. Cardiac arrhythmia detector using ECG waveform-factor and its irregularity
US7463922B1 (en) 2000-07-13 2008-12-09 Koninklijke Philips Electronics, N.V. Circuit and method for analyzing a patient's heart function using overlapping analysis windows
US6490478B1 (en) 2000-09-25 2002-12-03 Cardiac Science Inc. System and method for complexity analysis-based cardiac tachyarrhythmia detection
US6438419B1 (en) 2000-09-28 2002-08-20 The University Of Pittsburgh Method and apparatus employing a scaling exponent for selectively defibrillating a patient
US6741887B1 (en) 2000-12-01 2004-05-25 Ge Medical Systems Information Technologies, Inc. Apparatus and method for presenting periodic data
US6553257B2 (en) 2001-03-13 2003-04-22 Koninklijke Philips Electronics N.V. Interactive method of performing cardipulmonary resuscitation with minimal delay to defibrillation shocks
US20020165585A1 (en) 2001-05-01 2002-11-07 Dupelle Michael R. Pulse sensors
US6688303B2 (en) 2001-06-22 2004-02-10 Science Applications International Corporation Method and system for controlling operation of an energy conversion device
US6983183B2 (en) 2001-07-13 2006-01-03 Cardiac Science, Inc. Method and apparatus for monitoring cardiac patients for T-wave alternans
US6782293B2 (en) 2001-09-14 2004-08-24 Zoll Medical Corporation Defibrillation electrode assembly including CPR pad
GB0122746D0 (en) 2001-09-21 2001-11-14 Mills Desmond B Defibrillator
US6691053B2 (en) 2001-11-30 2004-02-10 Agilent Technologies, Inc. Method of matching retention times among multiple chromatographic system
US6778852B2 (en) 2002-03-14 2004-08-17 Inovise Medical, Inc. Color-coded ECG
US7027864B2 (en) 2002-04-17 2006-04-11 Koninklijke Philips Electronics N.V. Defibrillation system and method designed for rapid attachment
US7162298B2 (en) 2002-09-10 2007-01-09 Uab Research Foundation Devices for detecting the presence of cardiac activity following administration of defibrillation therapy
US6873133B1 (en) 2002-09-11 2005-03-29 Medtronic Physio-Control Manufacturing Corporation Defibrillator with a reconfigurable battery module
US7920917B2 (en) 2003-07-17 2011-04-05 Physio-Control, Inc. External defibrillator and methods for operating the external defibrillator
US7242979B1 (en) 2002-09-20 2007-07-10 Medtronic Physio-Control Manufacturing Corporation External defibrillator and methods for operating the external defibrillator
US7530257B2 (en) 2002-09-27 2009-05-12 Honeywell International Inc. Phased micro analyzer VIII
US7104112B2 (en) 2002-09-27 2006-09-12 Honeywell International Inc. Phased micro analyzer IV
US6827695B2 (en) 2002-10-25 2004-12-07 Revivant Corporation Method of determining depth of compressions during cardio-pulmonary resuscitation
US7031764B2 (en) 2002-11-08 2006-04-18 Cardiac Pacemakers, Inc. Cardiac rhythm management systems and methods using multiple morphology templates for discriminating between rhythms
US7970464B2 (en) 2002-11-13 2011-06-28 Physio-Control, Inc. Method and system for responding to non-perfusing and non-shockable heart rhythms
US7272441B1 (en) 2002-11-13 2007-09-18 Medtronic Physio-Control Manufacturing Corp. External defibrillator and methods for operating the external defibrillator
US9168385B2 (en) 2002-12-13 2015-10-27 Koninklijke Philips N.V. External defibrillator with shock activated by cessation of precordial compressions
US8036742B2 (en) 2003-01-31 2011-10-11 Physio-Control, Inc. Apparatus and methods for fibrillation and defibrillation
US7308304B2 (en) 2003-02-14 2007-12-11 Medtronic Physio-Control Corp. Cooperating defibrillators and external chest compression devices
US7569018B1 (en) 2003-02-18 2009-08-04 Purdue Research Foundation Apparatus and method for noninvasively detecting the quality of cardiac pumping
US6961612B2 (en) 2003-02-19 2005-11-01 Zoll Medical Corporation CPR sensitive ECG analysis in an automatic external defibrillator
US7522958B2 (en) 2003-03-13 2009-04-21 Uab Research Foundation Methods and systems for reducing discomfort from cardiac defibrillation shocks
US7079887B2 (en) 2003-03-20 2006-07-18 Medtronic, Inc. Method and apparatus for gauging cardiac status using post premature heart rate turbulence
US7805190B2 (en) 2003-04-02 2010-09-28 Physio-Control, Inc. Defibrillators customized for anticipated patients
US20040215244A1 (en) 2003-04-23 2004-10-28 Marcovecchio Alan F. Processing pulse signal in conjunction with ECG signal to detect pulse in external defibrillation
US7444179B2 (en) 2003-04-29 2008-10-28 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Devices, systems and methods for characterization of ventricular fibrillation and for treatment of ventricular fibrillation
US7680533B2 (en) 2003-06-25 2010-03-16 Zoll Medical Corporation Energy delivery apparatus and method
US7220235B2 (en) 2003-06-27 2007-05-22 Zoll Medical Corporation Method and apparatus for enhancement of chest compressions during CPR
US7190999B2 (en) 2003-06-27 2007-03-13 Zoll Medical Corporation Cardio-pulmonary resuscitation device with feedback from measurement of pulse and/or blood oxygenation
US7388459B2 (en) 2003-10-28 2008-06-17 Medtronic, Inc. MEMs switching circuit and method for an implantable medical device
US20050101889A1 (en) 2003-11-06 2005-05-12 Freeman Gary A. Using chest velocity to process physiological signals to remove chest compression artifacts
US7734344B2 (en) 2003-12-02 2010-06-08 Uab Research Foundation Methods, systems and computer program products to inhibit ventricular fibrillation during cardiopulmonary resuscitation
US7039457B2 (en) 2003-12-19 2006-05-02 Institute Of Critical Care Medicine Rhythm identification in compression corrupted ECG signal
US7567837B2 (en) 2003-12-19 2009-07-28 Institute Of Critical Care Medicine Enhanced rhythm identification in compression corrupted ECG
US7136694B2 (en) 2004-03-30 2006-11-14 Cardiac Science Corporation Methods for quantifying the morphology and amplitude of cardiac action potential alternans
EP1735052B1 (en) 2004-04-12 2015-03-04 Zoll Medical Corporation Automated pediatric defibrillator
US7593772B2 (en) 2004-04-30 2009-09-22 Lawrence Duane Sherman Methods and devices to characterize the probability of successful defibrillation and determine treatments for ventricular fibrillation
US7269454B2 (en) 2004-04-30 2007-09-11 Lawrence Duane Sherman Methods and devices to guide therapy for ventricular fibrillation based on waveform analysis and survival benefit analysis
WO2005107856A2 (en) 2004-05-04 2005-11-17 The Cleveland Clinic Foundation Methods of treating neurological conditions by neuromodulation of interhemispheric fibers
WO2006007048A2 (en) 2004-05-04 2006-01-19 The Cleveland Clinic Foundation Methods of treating medical conditions by neuromodulation of the sympathetic nervous system
EP1747041A4 (en) 2004-05-04 2008-06-18 Cleveland Clinic Foundation METHOD FOR THE TREATMENT OF MEDICAL CONDITIONS BY NEUROMODULATION OF THE CEREBELLAR PATHS
WO2005107854A2 (en) 2004-05-04 2005-11-17 The Cleveland Clinic Foundation Corpus callosum neuromodulation assembly
US7706878B2 (en) 2004-05-07 2010-04-27 Zoll Medical Corporation Automated caregiving device with prompting based on caregiver progress
US7565194B2 (en) 2004-05-12 2009-07-21 Zoll Medical Corporation ECG rhythm advisory method
WO2005112749A1 (en) 2004-05-12 2005-12-01 Zoll Medical Corporation Ecg rhythm advisory method
US7525279B2 (en) 2004-07-16 2009-04-28 General Electric Company System and method for minimizing the charge time of a battery
CN101232844A (zh) 2004-07-30 2008-07-30 捷通心脏系统公司 检测由cpr或患者动作引起的人为信号
ATE470271T1 (de) * 2004-09-09 2010-06-15 Epcos Ag Verbesserungen der oder in bezug auf antennenanpassung in videoempfängern
EP1804902A4 (en) 2004-09-10 2008-04-16 Cleveland Clinic Foundation INTRALUMINAL ELECTRODE ASSEMBLY
EP1804916A2 (en) 2004-09-24 2007-07-11 Roger Lee Heath Resuscitation and life support system, method and apparatus
JP2008514331A (ja) 2004-09-29 2008-05-08 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 経皮ペーシングのためのスイッチモード電源を有する除細動器
US7645247B2 (en) 2004-10-25 2010-01-12 Norman A. Paradis Non-invasive device for synchronizing chest compression and ventilation parameters to residual myocardial activity during cardiopulmonary resuscitation
US7904152B2 (en) 2004-12-09 2011-03-08 Physio-Control, Inc. External defibrillator with charge advisory algorithm
US7630762B2 (en) 2004-12-15 2009-12-08 Medtronic Emergency Response Systems, Inc. Medical device with resuscitation prompts depending on elapsed time
US7937146B2 (en) 2005-01-26 2011-05-03 Physio-Control, Inc. Defibrillator with overridable CPR-first protocol
US7805191B2 (en) 2005-01-31 2010-09-28 Physio-Control, Inc. CPR time indicator for a defibrillator data management system
US20060229679A1 (en) 2005-03-31 2006-10-12 Joo Tae H External defibrillator and a method of determining when to use the external defibrillator
US7559900B2 (en) 2005-04-22 2009-07-14 Medtronic, Inc. Cardiac sensing and detection using subcutaneous ECG signals and heart sounds
US7389147B2 (en) 2005-04-29 2008-06-17 Medtronic, Inc. Therapy delivery mode selection
JP2008543479A (ja) 2005-06-23 2008-12-04 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 自動ショックファースト／ｃｐｒファーストアルゴリズムを有する除細動器
EP1907051B1 (en) 2005-06-24 2017-09-13 Koninklijke Philips N.V. Aed having mandatory pause for administrating cpr
US20070213775A1 (en) 2005-07-19 2007-09-13 Koninklijke Philips Electronics N.V. External Defibrillator With Pre-Cpr-Ecg Based Defibrillating Shock
US7650181B2 (en) 2005-09-14 2010-01-19 Zoll Medical Corporation Synchronization of repetitive therapeutic interventions
US7657307B2 (en) 2005-10-31 2010-02-02 Medtronic, Inc. Method of and apparatus for classifying arrhythmias using scatter plot analysis
CN1989897A (zh) 2005-12-29 2007-07-04 深圳迈瑞生物医疗电子股份有限公司 基于复杂度的心室纤颤综合检测方法
US8105249B2 (en) 2006-02-16 2012-01-31 Zoll Medical Corporation Synchronizing chest compression and ventilation in cardiac resuscitation
US7697982B2 (en) 2006-04-27 2010-04-13 General Electric Company Synchronization to a heartbeat
CN101472648A (zh) * 2006-06-19 2009-07-01 皇家飞利浦电子股份有限公司 具有自动操作超驰控制的外部除颤器
US7738948B2 (en) 2006-10-31 2010-06-15 Medtronic, Inc. Form parameter forecaster for analyzing signals distorted by noise
EP2091610A1 (en) 2006-12-07 2009-08-26 Koninklijke Philips Electronics N.V. Aed having cpr period with pause for ecg acquisition
US7391257B1 (en) 2007-01-31 2008-06-24 Medtronic, Inc. Chopper-stabilized instrumentation amplifier for impedance measurement
US9986926B2 (en) 2007-10-26 2018-06-05 Inovise Medical, Inc. Q-onset ventricular depolarization detection in the presence of a pacemaker
US7986992B2 (en) 2007-11-16 2011-07-26 Ruse Technologies, Llc Apparatus and method for treating atrial fibrillation and atrial tachycardia
US7920918B2 (en) 2007-11-16 2011-04-05 Ruse Technologies, Llc Apparatus and method for treating ventricular fibrillation and ventricular tachycardia
US20090144903A1 (en) 2007-12-06 2009-06-11 Delvaux Andrew B Cpr facilitating mattress
US7783341B2 (en) 2008-01-07 2010-08-24 General Electric Company Method and apparatus for discerning therapeutic signals from noise in physiological data
RU2496413C2 (ru) 2008-01-14 2013-10-27 Конинклейке Филипс Электроникс Н.В. Мониторинг мерцательной аритмии
US20090270930A1 (en) 2008-04-25 2009-10-29 Physio-Control, Inc. External Defibrillator With Adaptive Protocols
EP2172245B1 (en) 2008-10-03 2017-04-12 Schiller Medical S.A.S. Apparatus for defibrillation delivery decision
US9539434B2 (en) 2009-10-02 2017-01-10 Physio-Control, Inc. Deciding on patient electric shock therapy
US9770183B2 (en) 2009-10-02 2017-09-26 Physio-Control, Inc. Analyzing ECG data in deciding on patient chest compression treatment
US8509881B2 (en) 2009-11-03 2013-08-13 Cardiac Science Corporation True ECG measurement during cardio pulmonary resuscitation by adaptive piecewise stitching algorithm
CN106310522A (zh) * 2010-02-12 2017-01-11 Zoll医疗公司 除颤器充电
US8725253B2 (en) * 2010-02-12 2014-05-13 Zoll Medical Corporation Defibrillator display including CPR depth information
JP6559954B2 (ja) * 2011-03-23 2019-08-14 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 選択的にｃｐｒを中断するためのプロトコルを伴なう除細動器

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006016289A2 (en) * 2004-08-09 2006-02-16 Koninklijke Philips Electronics, N.V. External defibrillator with pre-cpr-ecg based defibrillating shock
WO2007069162A1 (en) * 2005-12-16 2007-06-21 Koninklijke Philips Electronics, N.V. Automatic external defibrillator with increased cpr administration time

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