CN104491829A - 一种治疗月经过少的中药组合物及制备方法和应用 - Google Patents

一种治疗月经过少的中药组合物及制备方法和应用 Download PDF

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CN104491829A
CN104491829A CN201510023585.3A CN201510023585A CN104491829A CN 104491829 A CN104491829 A CN 104491829A CN 201510023585 A CN201510023585 A CN 201510023585A CN 104491829 A CN104491829 A CN 104491829A
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孙振双
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Abstract

本发明提供了一种治疗月经过少的中药组合物，它由如下重量份数的原料制备得到：鸡肫草、刺苋菜、柴胡、茯神等，本发明能治疗月经过少。

Description

一种治疗月经过少的中药组合物及制备方法和应用
技术领域
本发明涉及中药技术领域，具体涉及一种治疗月经过少的中药组合物及制备方法和应用。
背景技术
月经过少系由精血衰少，血海不盈，或痰阻瘀滞，血行不畅，致使经期虽准，但经量较正常明显减少，或经期不足2天经量少的月经病。目前缺少有效的治疗药物。
发明内容
发明目的：为了解决上述问题，本发明的目的在于提供一种治疗月经过少的中药组合物及制备方法和应用。
技术方案：本发明的目的是通过如下的方案实现的：
一种治疗月经过少的中药组合物，它由如下重量份数的原料制备得到：鸡肫草15份、刺苋菜12份、柴胡10份、茯神15份、白扁豆12份、女贞子15份、甘草6份、大枣12份、当归12份、白芍15份、桔梗10份、墨旱莲15份、薄荷10份、丹皮10份、山药30份、酸枣仁20份、枳实10份、鳖甲15份、生姜10份。
所述治疗月经过少的中药组合物在制备治疗月经过少的药物中的应用。
本发明中鸡肫草为虎耳科梅花草属植物鸡眼梅花草Parnassia wightiana Wall.以全草入药。夏秋采集全草，洗净晒干。刺苋菜为苋科植物刺苋Amaranthus spinosus L.的干燥全草或根。夏、秋季采收，除去泥沙，晒干或趁鲜切段，晒干。其余药物均符合药典标准或记载在中药大辞典中。
有益效果：本发明制得的药物能够安全有效治疗月经过少。
具体实施方式
以下通过实施例形式，对本发明的上述内容再作进一步的详细说明，但不应将此理解为本发明上述主题的范围仅限于以下的实例，凡基于本发明上述内容所实现的技术均属于本发明的范围。
1.制备实施例
1.1称取鸡肫草15g、刺苋菜12g、柴胡10g、茯神15g、白扁豆12g、女贞子15g、甘草6g、大枣12g、当归12g、白芍15g、桔梗10g、墨旱莲15g、薄荷10g、丹皮10g、山药30g、酸枣仁20g、枳实10g、鳖甲15g、生姜10g，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。用于治疗月经过少。口服，每日分早晚两次服用。
1.2称取鸡肫草15g、刺苋菜12g、柴胡10g、茯神15g、白扁豆12g、女贞子15g、甘草6g、大枣12g、当归12g、白芍15g、桔梗10g、墨旱莲15g、薄荷10g、丹皮10g、山药30g、酸枣仁20g、枳实10g、鳖甲15g、生姜10g，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，加淀粉，按常规工艺制粒，即得符合正常成人1天用量的颗粒剂。用于治疗月经过少。口服，每日分早晚两次服用。
1.3称取鸡肫草15g、刺苋菜12g、柴胡10g、茯神15g、白扁豆12g、女贞子15g、甘草6g、大枣12g、当归12g、白芍15g、桔梗10g、墨旱莲15g、薄荷10g、丹皮10g、山药30g、酸枣仁20g、枳实10g、鳖甲15g、生姜10g，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，加淀粉，按常规工艺制粒，压片，即可制得符合正常成人1天用量的片剂。用于治疗月经过少。口服，每日分早晚两次服用。
2.本发明对月经过少的临床研究
2.1一般资料：发明人2011年3月-2012年11月间共收集50例月经过少的门诊患者，年龄18-35岁，随机分为：治疗组30例，空白组20例。两组年龄、病情等资料无显著性差异，具有可比性。
2.2诊断标准：
2.2.1月经周期基本正常，经量很少，不足20ml，甚或点滴即净。
2.2.2本病应与早孕激经相鉴别。
2.2.3排除因结核病引起的月经过少。
2.2.4证候分类
2.2.4.1肝血亏虚：月经量少或点滴即净，色淡无块，或伴头晕眼花，心悸怔忡，面色萎黄，小腹空坠，舌质淡红，脉细。
2.2.4.2肾阳亏虚：月经量少，色淡红或黯红，质稀，腰脊酸软，头晕耳鸣，或小腹冷，夜尿多。舌质淡，脉弱或沉迟。
2.2.4.3瘀滞胞宫：月经量少，色紫黑，有血块，小腹胀痛，拒按，血块排出后胀痛减轻。舌正常或紫黯，或有瘀点，脉细弦涩。
2.2.4.4痰湿阻滞：月经量少，色淡红，质粘腻，形体肥胖，胸闷呕恶，或带多粘稠。苔白腻，脉滑。
2.3试验方法
2.3.1治疗组口服本发明按照具体实施例1.1制得的胶囊，早晚各一次。疗程15天。
2.3.2空白组口服安慰剂胶囊，早晚各一次。疗程15天。
2.4疗效标准与治疗结果
2.4.1疗效标准
痊愈：经量恢复正常，维持3个月以上。好转：经量明显增多。或经量恢复正常，但不能维持3个月以上。无效：经周期、经量无变化。
2.4.2治疗统计结果见表1。
表1两组疗效比较
组别 n 痊愈 好转 无效 总有效率(％)
治疗组 30 15 13 2 93.3
空白组 20 1 2 17 15
可见，本发明制得的药物能够安全有效治疗月经过少。

Claims (2)

1.一种治疗月经过少的中药组合物，其特征在于，它由如下重量份数的原料制备得到：鸡肫草15份、刺苋菜12份、柴胡10份、茯神15份、白扁豆12份、女贞子15份、甘草6份、大枣12份、当归12份、白芍15份、桔梗10份、墨旱莲15份、薄荷10份、丹皮10份、山药30份、酸枣仁20份、枳实10份、鳖甲15份、生姜10份。
2.如权利要求1所述治疗月经过少的中药组合物在治疗月经过少的药物中的应用。
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CN104906424A (zh) * 2015-06-25 2015-09-16 肖荣叶 一种治疗月经先期的中药组合物及其制备方法

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