CN104491368A - Traditional Chinese medicine for treating phlegmy turbidity stagnation type hyperlipidaemia - Google Patents
Traditional Chinese medicine for treating phlegmy turbidity stagnation type hyperlipidaemia Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating phlegmy turbidity stagnation type hyperlipidaemia. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 12 parts of pine nodular branch, 8 parts of the bark of ash, 3 parts of brucea javanica, 5 parts of grass of meadow rue, 2 parts of sunglow, 4 parts of fritillaria cirrhosa, 6 parts of silkworm excrement, 10 parts of folium eriobotryae, 2 parts of tamarind fruit, 5 parts of pig pancreas, 3 parts of rhizoma nardostachyos, 7 parts of textile screw pine seed, 2 parts of polygonum taipaishanense and 5 parts of perilla leaf. Clinical experiments prove that the traditional Chinese medicine can be used for safely and effectively treating phlegmy turbidity stagnation type hyperlipidaemia.
Description
Technical field
The present invention relates to a kind of Chinese medicine, especially relate to a kind of Chinese medicine for the treatment of stagnation of turbid phlegm in middle-JIAO type hyperlipemia.
Background technology
Hyperlipemia refers to that the content of one or several lipid components of human plasma exceedes normal peak limit.Primary disease occupies very consequence in Nutrition and Metabolism illness, is to cause one of atherosclerotic principal element, close with being related of hypertension, coronary heart disease and cerebrovascular, one of three large factors being regarded as coronary heart disease.In China, this disease is unrare, in recent years the trend that increases year by year in addition of its prevalence and mortality rate, in being especially more common in, old people.Primary disease primary disease, because of not bright, has family history and Genetic history more.Though modern medicine has multiple fat-reducing medicament, there is side effect and curative effect is unstable more.
For its common dyslipidemia in clinical manifestation of hyperlipemia people-as do not have too many sensation, unless when the blood lipid level in blood is higher, because blood viscosity increases sight-a little relevant symptom, as dizziness, blurred vision, uncomfortable in chest, numb limbs and tense tendons, hepatalgia etc.Some hyperlipidemia patient also has following performance:
1. dizzy is one of common early symptom of various hyperlipemia.Main cause is that long-term cerebral arteriosclerosis and blood viscosity increase and cause cerebral ischemia, anoxia.
2. the people of condition of being obese not only body fat tissue increase, and in blood, lipid also obviously increases, and especially triglyceride, free fatty and cholesterol levels exceed normally more.
3. suffer from abdominal pain recurrent exerbation heavy meal after of short duration stomachache be found in the Mesenteric artery hardening gastrointestinal ischemia that hyperlipemia causes; In the persistence of acute attack after high fat diet, upper abdominal pain mostly is acute pancreatitis.
4. limbs weak blood fat raise early stage, patient just can have the weak or movable rear pain of companion of limbs, may be relevant with fat metabolic disturbance and circulatory disturbance.
5. eye pouch remarkable " eye pouch " is that significant quantities of fat is deposited in the palpebra inferior subcutaneous tissue of people, defines a semicircular satchel in the course of time.
6. liver injury can cause fatty liver due to hyperlipidemia, thus causes liver enlargement, there will be the change of hepatic disease and liver function, also there will be inappetence etc. to a certain extent.Can find during health check-up that liver increases, can also occur that transaminase raises.
7. the patient that tendon infringement suffers from familial hypercholesterolemia be everlasting elbow, knee joint, ankle, finger-joint stretch surface skin generation lipid dystopy deposition.Heel string is the predilection site of lipidosis.Sometimes Spontaneous Achilles ' Tendon Ruptures is the onset symptom of familial hypercholesterolemia.
At present the effective medicine of generally recognized as safe is still lacked at present for stagnation of turbid phlegm in middle-JIAO type hyperlipemia.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Lignum Pini Nodi
[source] medical material Ji Yuan: be the tuberosity of the branchs such as pinaceae plant Pinus tabuliformis, Pinus massoniana Lamb, Pinus densiflora, pinus yunnanensis faranch.
[function cures mainly] dispeiling pathogenic wind and removing dampness; Channels sootheing and network vessel quickening; Promoting blood circulation and stopping pain.
[usage and dosage] takes orally: decoct soup, 10-15g
Cortex Fraxini
[source] is Oleaceae plants fraxinus rhynchophylla Hance, the bark of Fraxinus bungeana or Qinling Mountains Chinese ash.
[function cures mainly] heat clearing and damp drying, antiasthmatic-antitussive, improving eyesight.
[usage and dosage] 6 ~ 12g.Suitable amount used externally, decocts and washes affected part.
Fructus Bruceae
[source] is the fruit of quassia Fructus Bruceae.
[function cures mainly] heat clearing away, dampness, parasite killing, removing toxic substances.
[usage and dosage] takes orally: with Arillus Longan or capsule parcel, swallow after meal, each 5 ~ 20,3 times on the 1st.
Thalictrum aquilegifolium L. var. sibiricum Regel
[source] medical material Ji Yuan: be the root and rhizome of ranunculaceae plant Thalictrum aquilegifolium L. var. sibiricum Regel.
[function cures mainly] clearing away heat-fire; Dampness is detoxified.
[usage and dosage] takes orally: decoct soup, 5-10g
Usnea
[source] is Usneaceae plant Usnea Longissima, the filamentous of broken stem Usnea.
[function cures mainly] liver heat removing, reduces phlegm, hemostasis, removing toxic substances.
[usage and dosage] takes orally: decoct soup, 2 ~ 3 money.
Bulbus Fritillariae Cirrhosae
[source] is liliaceous plant Fritillaria Cirrhosa D. Don, the bulb of crow flower Bulbus Fritillariae Uninbracteatae or rib sand Bulbus Fritillariae Uninbracteatae etc.
[function cures mainly] clearing heat and moistening lung, preventing phlegm from forming and stopping coughing.For lung-heat type cough, the few expectorant of dry cough, deficiency of YIN chronic cough, sputum with blood.
[usage and dosage] 3 ~ 9g; Levigation is taken after mixing it with water, a 1 ~ 2g.
Bombyx mori L.
[source] medical material Ji Yuan: be the dry feces of Bombycidae animal bombyx mori larva.
[function cures mainly] expelling wind and removing dampness; Regulating the function of the stomach to resolve the turbidity; Promoting blood circulation to restore menstrual flow.
[usage and dosage] takes orally: decoct soup, 10-15g
Folium Eriobotryae
[source] medical material Ji Yuan: be the leaf of rosaceous plant Folium Eriobotryae.
[function cures mainly] clearing away lung-heat to relieve cough, regulating the stomach and sending down the abnormal ascending QI, quenches the thirst.
[usage and dosage] takes orally: decoct soup, 9-15g, heavy dose of available to 30g, fresh goods 15-30g; Or endure cream, or enter ball, loose.
Fructus Tamarindi Indicae
[source] is the fruit of leguminous plant tamarind.
[function cures mainly] clearing away summer-heat heat, eliminate indigestion is stagnant.
[usage and dosage] takes orally: decoct soup, 0.5 ~ 1 liang; Or endure cream.
Pancreas Sus domestica
[source] is the pancreas of porcine animals pig.
[function cures mainly] lung benefiting, spleen reinforcing, moisturizes.
[usage and dosage] takes orally: cook or decoct soup.
Radix Et Rhizoma Nardostachyos
The rhizome that [source] is Valerianaceae plant Nardostachys chinensis Batal. or jatamansi and root.
[function cures mainly] regulating QI to relieve pain, relieving stagnation and activating the spleen.
[usage and dosage] 3 ~ 6g.
Fructus Pandani tectorii
[source] medical material Ji Yuan: be the drupe of Pandanaceae plant Pandanus tectorius.
[function cures mainly] spleen reinforcing benefit blood; Promoting the circulation of QI to relieve pain; Reduce phlegm dampness removing; Improving eyesight.
[usage and dosage] takes orally: decoct soup, 10-30g
Rhizoma Bergeniae scopulosae
[source] medical material Ji Yuan: be the rhizome of saxifragaceae plant Qinling Mountains Rhizoma Seu Herba Bergeniae.
[function cures mainly] spleen reinforcing stomach invigorating, the solid intestinal of astringent therapy, eliminating dampness and promoting diuresis, invigorates blood circulation.
[usage and dosage] takes orally: decoct soup 2 ~ 3 money.External: grind into powder and dress.
Folium Perillae
[source] medical material Ji Yuan: be leaf or the little switch of band leaf of labiate Folium Perillae and wild Folium Perillae.
[function cures mainly] expelling cold and relieving exterior syndrome; Dispersing lung-QI and dissipating phlegm; Circulation of qi promoting and in.
[usage and dosage] takes orally: decoct soup, 5-10g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of stagnation of turbid phlegm in middle-JIAO type hyperlipemia, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing stagnation of turbid phlegm in middle-JIAO type hyperlipemia.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of stagnation of turbid phlegm in middle-JIAO type hyperlipemia, it is characterized in that, be prepared from by the medical material of following weight proportion: Lignum Pini Nodi 12 parts, Cortex Fraxini 8 parts, Fructus Bruceae 3 parts, Thalictrum aquilegifolium L. var. sibiricum Regel 5 parts, Usnea 2 parts, Bulbus Fritillariae Cirrhosae 4 parts, Bombyx mori L. 6 parts, Folium Eriobotryae 10 parts, Fructus Tamarindi Indicae 2 parts, Pancreas Sus domestica 5 parts, Radix Et Rhizoma Nardostachyos 3 parts, Fructus Pandani tectorii 7 parts, 2 parts, Rhizoma Bergeniae scopulosae, Folium Perillae 5 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects the out-patient of 100 routine stagnation of turbid phlegm in middle-JIAO type hyperlipemias altogether between in June ,-2014 in January, 2011, age 32-61 year, course of disease 1-3.Be divided at random: treatment group 70 example, blank group 30 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, diagnosis basis
With reference to the traditional Chinese medical science for stagnation of turbid phlegm in middle-JIAO type hyperlipemia Standardization of diagnosis and curative effect be:
Stagnation of turbid phlegm in middle-JIAO:
Syndrome: obesity, palpitation and dizziness, feeling of oppression and fullness in the chest and epigastrium, abdominal distension and anorexia, weak asthenia, nausea and salivation, feeling thirst but no desire to drink water, pale and corpulent tongue with indented margin, greasy fur, soft pulse.
Syndrome analysis: fertile people's excessive phlegm wets, stagnation of turbid phlegm in middle-JIAO, and clear YANG failing to ascend is then dizzy; Turbid YIN failing to descend event nausea and salivation, middle burnt mechanism of qi does not fall therefore has the disease such as feeling of oppression and fullness in the chest and epigastrium, abdominal distention; The then thirsty and not tending to drink water of body fluid cannot flow upwards; The disease such as phlegm-damp is stranded spleen, dysfunction of the spleen in transportation there will be indigestion and loss of appetite, weak, asthenia.Pale and corpulent tongue with indented margin, greasy fur, soft pulse is resembling of stagnation of turbid phlegm in middle-JIAO.
3, test method
The capsule that the oral the present invention of 3.1 treatment group obtains according to specific embodiment 1, sooner or later respectively once, 15 days courses for the treatment of.
3.2 blank group oral placebo capsules, sooner or later respectively once.15 days courses for the treatment of.
4, criterion of therapeutical effect and therapeutic outcome
4.1 criterion of therapeutical effect
With reference to the industry standard " Chinese medical disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine promulgates, for stagnation of turbid phlegm in middle-JIAO type hyperlipemia efficacy evaluation:
4.1.1 effective: clinical symptoms, sign disappear substantially, lipids detection reaches following any one person.
TC decline >=20%, TG decline >=40%, HDL-C rising >=0.26mmol/L(10mg/d1), TC-HDL-C/HDL-C declines >=20%.
4.1.2 effective: lipids detection reaches following any one person.
TC declines >=10% but < 20%, TG declines >=20% but < 40%, HDL-C rising >=0.104mmol/L (4mg/dl) but < 0. 26mmol/L(10mg/dl), TC-HDL-C/HDL-C declines >=10% but < 20%.
4.1.3 invalid: symptom, sign and the lipids detection person of being not improved after treatment.
4.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) | Untoward reaction example |
Treatment group | 70 | 27(38.6%) | 33(47.1%) | 10(14.3%) | 85.7% | 0 |
Blank group | 30 | 0(0%) | 4(13.3%) | 26(86.6%) | 13.3% | 0 |
For proving that the present invention has good curative effect, enumerate model case as follows:
1, Lee, man, 39 years old, workman, this human body type is comparatively fat, and telling the nearly section time has dizziness, cardiopalmus, situation uncomfortable in chest, and affects daily life, work with limbs are weak, simultaneously, in mouthful, damp-phlegm is more, goes to local hospital medical by the detection such as empty stomach TC, TG, LDL-C, HDL-C subsequently, is diagnosed as stagnation of turbid phlegm in middle-JIAO type hyperlipemia disease, rear hospital adopts doctor trained in Western medicine routine medication one week rear poor effect, and with exacerbation of symptoms trend.After give treatment by Chinese herbs of the present invention, after taking one week, dizzy, uncomfortable in chest, damp-phlegm etc. obviously reduce, and continuous with after one month, the state of an illness is clearly better, and there is no recurrence so far.
2, Cai, female, 51 years old, first visit on February 2 in 2014.I am fat; body weight is up to more than 200 jin; its main suit: dizziness in the recent period obviously has hypoxic conditions; numb limbs and tense tendons, blurred vision, usually have the performance of middle upper abdominal pain, and go to local hospital subsequently in time after diet; hospital is by TC, TG, LDL-C, HDL-C, the inspection of plasma low density lipoprotein (LDL-C) concentration etc. diagnosis on an empty stomach; be diagnosed as stagnation of turbid phlegm in middle-JIAO type hyperlipemia disease subsequently, hospital adopts western medical treatment immediately, loses symptom take a turn for the better to some extent through treatment in 4 days.After give treatment by Chinese herbs of the present invention, after taking 3 days, complexion, dizziness, vision etc. are progressively recovered normally, and stomachache situation obviously reduces, and after continuing to take one month, state of an illness rehabilitation is complete, and so far without recurring.
3, money, man, 32 years old, suffer from hyperlipemia 2 years, took place frequently dizziness recently, tinnitus, and conscious order is puckery dim-sighted, dry mouth and throat, in pharynx sticky expectorant cough up tell not well, susceptible to lose temper due to restlessness, soreness of the waist and knees, lassitude of the limbs and weakness, afternoon flushed cheeks, red tongue with a little fluid, thready pulse stringy and rapid pulse.Eyelet has the xanthelasma of multiple Semen Sesami size.Middle triglyceride of closely having a blood test reaches 300mg%.Comprehensive analysis to both pulse manifestation and symptoms is by the hepatic and renal YIN deficiency, and asthenic fire refining liquid becomes caused by expectorant, should nourishing the liver and kidney be main.Classified by tcm syndrome and be diagnosed as it and belong to stagnation of turbid phlegm in middle-JIAO type hyperlipemia, adopt traditional Chinese medical science conventional therapy after hospital, after one week, symptom is not felt any better.Give treatment by Chinese herbs of the present invention subsequently, after taking one week, make coherence check and be all tending towards normalization, sudden colic symptoms obviously alleviates, and takes so far always, and the reaction of patient's each side is good, there is no recurrence, and normally can work, lives.
Visible, the present invention adopts the formula of science and suitable proportioning, cooperatively interacts between each medicine, synergism, and adopt the spleen strengthening and damp drying, the principle for the treatment of of the stomach function regulating that reduces phlegm, made Chinese medicine can safe and effective treatment stagnation of turbid phlegm in middle-JIAO type hyperlipemia.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Lignum Pini Nodi 12 grams, Cortex Fraxini 8 grams, Fructus Bruceae 3 grams, Thalictrum aquilegifolium L. var. sibiricum Regel 5 grams, Usnea 2 grams, Bulbus Fritillariae Cirrhosae 4 grams, Bombyx mori L. 6 grams, Folium Eriobotryae 10 grams, Fructus Tamarindi Indicae 2 grams, Pancreas Sus domestica 5 grams, Radix Et Rhizoma Nardostachyos 3 grams, Fructus Pandani tectorii 7 grams, 2 grams, Rhizoma Bergeniae scopulosae, Folium Perillae 5 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of stagnation of turbid phlegm in middle-JIAO type hyperlipemia.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: Lignum Pini Nodi 12 grams, Cortex Fraxini 8 grams, Fructus Bruceae 3 grams, Thalictrum aquilegifolium L. var. sibiricum Regel 5 grams, Usnea 2 grams, Bulbus Fritillariae Cirrhosae 4 grams, Bombyx mori L. 6 grams, Folium Eriobotryae 10 grams, Fructus Tamarindi Indicae 2 grams, Pancreas Sus domestica 5 grams, Radix Et Rhizoma Nardostachyos 3 grams, Fructus Pandani tectorii 7 grams, 2 grams, Rhizoma Bergeniae scopulosae, Folium Perillae 5 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, the powder of adult normal's 1 day consumption must be met.
Be used for the treatment of stagnation of turbid phlegm in middle-JIAO type hyperlipemia.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: Lignum Pini Nodi 12 grams, Cortex Fraxini 8 grams, Fructus Bruceae 3 grams, Thalictrum aquilegifolium L. var. sibiricum Regel 5 grams, Usnea 2 grams, Bulbus Fritillariae Cirrhosae 4 grams, Bombyx mori L. 6 grams, Folium Eriobotryae 10 grams, Fructus Tamarindi Indicae 2 grams, Pancreas Sus domestica 5 grams, Radix Et Rhizoma Nardostachyos 3 grams, Fructus Pandani tectorii 7 grams, 2 grams, Rhizoma Bergeniae scopulosae, Folium Perillae 5 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, can obtain the granule meeting adult normal's 1 day consumption.
Be used for the treatment of stagnation of turbid phlegm in middle-JIAO type hyperlipemia.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. treat the Chinese medicine of stagnation of turbid phlegm in middle-JIAO type hyperlipemia for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: Lignum Pini Nodi 12 parts, Cortex Fraxini 8 parts, Fructus Bruceae 3 parts, Thalictrum aquilegifolium L. var. sibiricum Regel 5 parts, Usnea 2 parts, Bulbus Fritillariae Cirrhosae 4 parts, Bombyx mori L. 6 parts, Folium Eriobotryae 10 parts, Fructus Tamarindi Indicae 2 parts, Pancreas Sus domestica 5 parts, Radix Et Rhizoma Nardostachyos 3 parts, Fructus Pandani tectorii 7 parts, 2 parts, Rhizoma Bergeniae scopulosae, Folium Perillae 5 parts.
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CN201510000879.4A Pending CN104491368A (en) | 2015-01-04 | 2015-01-04 | Traditional Chinese medicine for treating phlegmy turbidity stagnation type hyperlipidaemia |
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Citations (5)
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CN1304769A (en) * | 2001-01-21 | 2001-07-25 | 白玛加措 | Blood-cleaning pill |
KR20070038487A (en) * | 2007-03-21 | 2007-04-10 | 박선동 | Extracted admixtures for cerebral thrombosis and coronary thrombosis and for prophylax of glycosuria |
CN101559181A (en) * | 2009-05-25 | 2009-10-21 | 吴清玲 | Medicine for treating hyperlipidemia and preparation method thereof |
CN103751742A (en) * | 2014-01-05 | 2014-04-30 | 吴红英 | Preparation method of traditional Chinese medicine for treating wind-cold-headache-type hyperlipemia |
CN103751496A (en) * | 2014-01-05 | 2014-04-30 | 董帅 | Preparation method of traditional Chinese medicine for treating cold-dampness-disturbing-spleen-type hyperlipemia |
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CN1304769A (en) * | 2001-01-21 | 2001-07-25 | 白玛加措 | Blood-cleaning pill |
KR20070038487A (en) * | 2007-03-21 | 2007-04-10 | 박선동 | Extracted admixtures for cerebral thrombosis and coronary thrombosis and for prophylax of glycosuria |
CN101559181A (en) * | 2009-05-25 | 2009-10-21 | 吴清玲 | Medicine for treating hyperlipidemia and preparation method thereof |
CN103751742A (en) * | 2014-01-05 | 2014-04-30 | 吴红英 | Preparation method of traditional Chinese medicine for treating wind-cold-headache-type hyperlipemia |
CN103751496A (en) * | 2014-01-05 | 2014-04-30 | 董帅 | Preparation method of traditional Chinese medicine for treating cold-dampness-disturbing-spleen-type hyperlipemia |
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Application publication date: 20150408 |