CN104491145B - A kind of acne cream - Google Patents
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- CN104491145B CN104491145B CN201410766328.4A CN201410766328A CN104491145B CN 104491145 B CN104491145 B CN 104491145B CN 201410766328 A CN201410766328 A CN 201410766328A CN 104491145 B CN104491145 B CN 104491145B
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/614—Cnidaria, e.g. sea anemones, corals, coral animals or jellyfish
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/734—Alginic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
The invention provides a kind of acne cream, is made up of yellow sea anemone, sodium alginate, borneol, frankincense, myrrh, garden burnet, dandelion, glutinous rehmannia, semen armeniacae amarae, vaseline.Acne cream of the present invention, there is short treating period, it is quick, it is uneasy to recur the characteristics of, while hemorrhoid are treated, prevent wound infection, while recover the elasticity of patient's anus portion skin.
Description
Technical field
The present invention relates to field of medicaments, more particularly to a kind of acne cream.
Background technology
The soft venous group that expansion and flexing are formed occurs for veniplex under the mucous membrane of human rectum end and under anal canal skin,
Referred to as hemorrhoid, also known as hemorrhoid, haemorrhoids, hemorrhoid disease, haemorrhoids etc..Medical science meaning hemorrhoid include internal piles, external piles, mixed hemorrhoid, are anal orifice and rectal intestines
A kind of chronic disease of the venous group for the one or more softness that the veniplex of bottom and anal mucosa occurs varicose and formed.Mesh
Before, in China, the incidence of disease of recial disease is 59.1%, and hemorrhoid account for all anorectal diseases 87.25%, and wherein with internal piles the most
It is common, account for the 52.19% of all anorectal diseases.Men and women can fall ill, and the incidence of disease of women is 67%, and the incidence of disease of male is
53.9%；Any age can all fall ill, and the wherein people of 20-40 year is more common, and aggravates with advancing age and gradually, therefore
It is said that nine out ten suffer from hemorrhoids.
At present, treating the medicine of hemorrhoid has external application, takes two kinds orally, such as the Suppository for treatment of pile of external application, acne cream, local injection medication
Deng taking orally as Chinese medicine, Western medicine etc..Present medicine either externally applied drug or innerlich anwenden, all can only pain of alleviation, it is impossible to thoroughly control
More, easily recur, the great pains such as obstinate brings swelling and pain to patient, had blood in stool.Simultaneously because anus part skin is repeatedly
Breakage, easily cause infection.
The content of the invention
To obtain new and effective safe medicine for being applicable to treat hemorrhoid and preparation method thereof, the present inventor passes through to this
Substantial amounts of further investigation is crossed, after sufficient creative work has been paid, completes the present invention.
For the etiology and pathogenesis of hemorrhoid, the present invention is rotten using removing pattogenic heat from the blood and toxic material from the body, anti-inflammatory analgesic, promoting blood circulation and removing blood stasis, convergence clearing damp, change
The medicine of myogenic carries out diagnosis and treatment.
The present invention relates to a kind of acne cream, by yellow sea anemone, sodium alginate, borneol, frankincense, myrrh, garden burnet, dandelion,
Huang, semen armeniacae amarae, vaseline composition.
As it is a kind of it is exemplary enumerate, in described pharmaceutical composition, in parts by weight, its concrete component content is as follows：
Yellow sea anemone 5-10 parts, sodium alginate 15-20 parts, borneol 5-10 parts, frankincense 10-15 parts, myrrh 5-10 parts, garden burnet 8-
12 parts, dandelion 5-15 parts, glutinous rehmannia 8-12 parts, semen armeniacae amarae 5-10 parts, 100 parts of vaseline.
Preferably, 8 parts of yellow sea anemone, 18 parts of sodium alginate, 7 parts of borneol, 12 parts of frankincense, 8 parts of myrrh, 10 parts of garden burnet, Pu Gong
12 parts of English, 10 parts of glutinous rehmannia, 8 parts of semen armeniacae amarae, 100 parts of vaseline.
A kind of acne cream as described above, its preparation method are：1) yellow sea anemone, borneol, breast, are weighed according to the parts by weight
Perfume, myrrh, garden burnet, dandelion, glutinous rehmannia, semen armeniacae amarae, after clear water soaks 2 hours, add the decocting 2.5~3.5 of 13~17 times of weight
Hour, filter centrifugation removes slag, and concentrates, and is cooled to room temperature and adds sodium alginate, is prepared into clear cream；2), by clear cream obtained by step 1)
Be heated to 50-80 DEG C 100 parts of vaseline it is well mixed ointment is made, produce the acne cream.
Preferably, in step 1) for plus 15 times of weight decocting 3 hours.
Taboo：During medication, prohibit pungent, wine, life, cool, food really up to the mark, fried food, beverage.
The effectiveness of each composition in above-mentioned formula：
Yellow sea anemone：《Medical Animals In China will》：There is the effect of astringent or styptic treatment for spontaneous sweating convergence, removing dampness and destroying parasites.Control hemorrhoid, prolapse of the anus, leukorrhea mistake
More, pinworm etc..
Sodium alginate：Hemostasis and anti-inflammation, myogenic.Thickener as the present invention simultaneously.
Borneol：Radiating analgesic, is used for the treatment of sore mange.
Frankincense：Activate blood and relax tendons, promoting qi circulation and relieving pain.
Myrrh：The promoting flow of qi and blood circulation, swelling and pain relieving.
Garden burnet：Clearing heat and cooling blood, astringing to arrest bleeding, effective anti-inflammatory are antibacterial.
Dandelion：It is clearing heat and detoxicating, dispersing swelling and dissipating binds, anti-inflammation.
Glutinous rehmannia：Clearing heat and promoting fluid, after cool, hemostasis.
Semen armeniacae amarae：Anti-inflammatory, analgesia.
Wherein, the present invention is by refrigerant hemostasis, the medicine mating reaction of anti-inflammatory analgesic, removing necrosis, promoting granulation, by marine drug and in
Herbal medicine reasonable combination, while hemostasis by sodium alginate, thickening, clear cream is prepared, sodium alginate can be by the medicine of other components
Rationally uniform absorption, can make lasting medicine.Meanwhile medicine of the present invention, it can effectively maintain patient's anus portion skin
Elasticity, it can also prevent and treat the infection in patient's anus portion.
Beneficial effects of the present invention：
Acne cream of the present invention, there is short treating period, it is quick, it is uneasy to recur the characteristics of, while hemorrhoid are treated,
Wound infection is prevented, while recovers the elasticity of patient's anus portion skin.
Embodiment
Below by specific embodiment, the present invention is described in detail, but the purposes of these exemplary embodiments and
Purpose is only used for enumerating the present invention, not forms any type of any restriction to the real protection scope of the present invention, more non-to incite somebody to action
Protection scope of the present invention is confined to this.
Embodiment 1
A kind of acne cream, in parts by weight, its concrete component content are as follows：
5 parts of yellow sea anemone, 15 parts of sodium alginate, 5 parts of borneol, 10 parts of frankincense, 5 parts of myrrh, 8 parts of garden burnet, 5 parts of dandelion,
Yellow 8 parts, 5 parts of semen armeniacae amarae, 100 parts of vaseline.
Specific preparation method is as follows：
1), according to the parts by weight weigh yellow sea anemone, sodium alginate, borneol, frankincense, myrrh, garden burnet, dandelion, glutinous rehmannia,
Semen armeniacae amarae, after clear water soaks 2 hours, add the decocting of 13~17 times of weight 2.5~3.5 hours, filter centrifugation removes slag, and concentrates, drop
Warm to room temperature addition sodium alginate and be prepared into clear cream；2) clear cream obtained by step 1), is heated to 50-80 DEG C of vaseline
100 parts well mixed to be made ointment, produces the acne cream.
Embodiment 2
A kind of acne cream, in described pharmaceutical composition, in parts by weight, its concrete component content is as follows：
10 parts of yellow sea anemone, 20 parts of sodium alginate, 10 parts of borneol, 15 parts of frankincense, 10 parts of myrrh, 12 parts of garden burnet, dandelion 15
Part, 12 parts of glutinous rehmannia, 10 parts of semen armeniacae amarae, 100 parts of vaseline.Specific preparation method is as follows：
With embodiment 1.
Embodiment 3
A kind of acne cream, in described pharmaceutical composition, in parts by weight, its concrete component content is as follows：
8 parts of yellow sea anemone, 18 parts of sodium alginate, 7 parts of borneol, 12 parts of frankincense, 8 parts of myrrh, 10 parts of garden burnet, 12 parts of dandelion,
10 parts of glutinous rehmannia, 8 parts of semen armeniacae amarae, 100 parts of vaseline.
Specific preparation method is as follows：
With embodiment 1.
Case and clinical effectiveness：
Case 1：Liu, man, 31 years old, constipation, there is blood during stool, post-defecatory pain, be diagnosed as anal fissure bleeding on inspection, use
Acne cream of the present invention, fully recover within 6 days.
Case 2：Poplar, female, 23 years old, perianal abscess, using acne cream of the present invention, fully recover within 3 days.
Case 3：Zhang, man, 43 years old, crissum swelling and pain, fecal blood, using acne cream of the present invention, symptom disappeared after 3 days
Lose.
Case 4：Mr. Wang, male 55 years old, hemorrhoid cutting operation postoperative infection, using acne cream of the present invention, fully recover within 7 days.
Case 5：Is sought, man, 39 years old, anal fistula post-operative wound disunion, and using acne cream of the present invention, 15 days more
Close.
Hemorrhoid diagnosis and treatment standard：The I phases, no pain, mainly to have blood in stool, secretion is more, itch based on；The II phases, have blood in stool, hemorrhoid are with row
Just prolapse, but voluntarily can also receive；The III phases (also known as late period), interior prolapse of hemorrhoid is in outside anal orifice, or defecation abjection anal orifice every time
Outside, it is impossible to voluntarily also receive, it is necessary to returned with hand rest.
It is effective：Above clinical symptoms all disappear；
Effectively：Above clinical symptoms partial disappearance；
It is invalid：Effective and effective evaluation criteria person is not reached.
Choose 150 hemorrhoid patients, the wherein people of I phases 80, the people of II phases 55, the people of III phases 15.
By accumulative 150 hemorrhoid patients using the treatment effect after piles medicine of the present invention 7 days, after 15 days, and in 1 year
After carry out paying a return visit recovery from illness patient, count recurrence rate, it is daily to smear 2 times.Statistical result is shown in Table 1~3.
Treatment results see the table below (table 1, table 2)：
Table 1. is to I phase patient treatment outcome examples (%)
Table 2. is to II phase patient treatment outcome examples (%)
Table 3. is to III phase patient treatment outcome examples (%)
Above-mentioned clinical research shows：Acne cream of the present invention has significant therapeutic effect to I phase patients, short treating period,
And without recurrence, to II, III patient, it may have it is notable the effect of, after treatment 15 days, obvious effective rate can respectively reach 96.37%,
80%, and low recurrence rate.Through treating patient's items clinical symptom disappearance, quality of life improves, and does not occur symptom deterioration person.
It should be appreciated that the purposes of these embodiments is merely to illustrate the present invention and is not intended to the protection model of the limitation present invention
Enclose.In addition, it should also be understood that, after the technology contents of the present invention have been read, those skilled in the art can make each to the present invention
Kind change, modification and/or variation, all these equivalent form of values equally fall within the guarantor that the application appended claims are limited
Within the scope of shield.
Claims (2)
- A kind of 1. acne cream, it is characterised in that：The acne cream by yellow sea anemone, sodium alginate, borneol, frankincense, myrrh, garden burnet, Dandelion, glutinous rehmannia, semen armeniacae amarae, vaseline, the acne cream each component are in parts by weight：Yellow sea anemone 5-10 parts, alginic acid Sodium 15-20 parts, borneol 5-10 parts, frankincense 10-15 parts, myrrh 5-10 parts, garden burnet 8-12 parts, dandelion 5-15 parts, glutinous rehmannia 8-12 Part, semen armeniacae amarae 5-10 parts, 100 parts of vaseline.
- 2. a kind of acne cream as claimed in claim 1, it is characterised in that the acne cream each component is in parts by weight： 8 parts of yellow sea anemone, 18 parts of sodium alginate, 7 parts of borneol, 12 parts of frankincense, 8 parts of myrrh, 10 parts of garden burnet, 12 parts of dandelion, 10 parts of glutinous rehmannia, 8 parts of semen armeniacae amarae, 100 parts of vaseline.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410766328.4A CN104491145B (en) | 2014-12-04 | 2014-12-04 | A kind of acne cream |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410766328.4A CN104491145B (en) | 2014-12-04 | 2014-12-04 | A kind of acne cream |
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| Publication Number | Publication Date |
|---|---|
| CN104491145A CN104491145A (en) | 2015-04-08 |
| CN104491145B true CN104491145B (en) | 2018-03-13 |
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| CN201410766328.4A Expired - Fee Related CN104491145B (en) | 2014-12-04 | 2014-12-04 | A kind of acne cream |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113750040A (en) * | 2021-10-30 | 2021-12-07 | 贵州中医药大学 | Traditional Chinese medicine hemorrhoid ointment and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1327833A (en) * | 2001-06-15 | 2001-12-26 | 姜莉蔚 | Exterior-applied ointment for treating piles |
| CN1546160A (en) * | 2003-12-09 | 2004-11-17 | 鲁汝协 | Externally applied medicine for treating hemorrhoids and its preparation |
| CN101219179A (en) * | 2007-12-10 | 2008-07-16 | 北京中科雍和医药技术有限公司 | Chinese composition medicine for treating piles and method of preparing the same |
| CN101698036A (en) * | 2009-11-10 | 2010-04-28 | 南京中医药大学 | Traditional Chinese medicine for treating haemorrhoids, traditional Chinese medicine cataplasm and preparation method thereof |
| CN102119975A (en) * | 2011-03-07 | 2011-07-13 | 李仲甫 | Chinese herbal medicine ointment for treating ulcer, bedsore, vasculitic dermatosis and infectious dermatosis |
| CN102552611A (en) * | 2012-02-24 | 2012-07-11 | 北京市肛肠医院 | Traditional Chinese medicine combination for treating haemorrhoids |
-
2014
- 2014-12-04 CN CN201410766328.4A patent/CN104491145B/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1327833A (en) * | 2001-06-15 | 2001-12-26 | 姜莉蔚 | Exterior-applied ointment for treating piles |
| CN1546160A (en) * | 2003-12-09 | 2004-11-17 | 鲁汝协 | Externally applied medicine for treating hemorrhoids and its preparation |
| CN101219179A (en) * | 2007-12-10 | 2008-07-16 | 北京中科雍和医药技术有限公司 | Chinese composition medicine for treating piles and method of preparing the same |
| CN101698036A (en) * | 2009-11-10 | 2010-04-28 | 南京中医药大学 | Traditional Chinese medicine for treating haemorrhoids, traditional Chinese medicine cataplasm and preparation method thereof |
| CN102119975A (en) * | 2011-03-07 | 2011-07-13 | 李仲甫 | Chinese herbal medicine ointment for treating ulcer, bedsore, vasculitic dermatosis and infectious dermatosis |
| CN102552611A (en) * | 2012-02-24 | 2012-07-11 | 北京市肛肠医院 | Traditional Chinese medicine combination for treating haemorrhoids |
Non-Patent Citations (1)
| Title |
|---|
| 中医对痔的研究概况;席作武;《中医对痔的研究概况》;20140628;第20卷(第6期);第862-863页 * |
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