CN104488947A - Pharmaceutical composition for preventing and treating thrips palmi - Google Patents
Pharmaceutical composition for preventing and treating thrips palmi Download PDFInfo
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- CN104488947A CN104488947A CN201410701429.3A CN201410701429A CN104488947A CN 104488947 A CN104488947 A CN 104488947A CN 201410701429 A CN201410701429 A CN 201410701429A CN 104488947 A CN104488947 A CN 104488947A
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- imidacloprid
- avermectin
- pharmaceutical composition
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- yellow thrips
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Abstract
The invention belongs to the technical field of pesticides and particularly discloses a pharmaceutical composition for preventing and treating thrips palmi. The pharmaceutical composition comprises abamectin and imidacloprid, wherein the mixing volume rate of crude abamectin to crude imidacloprid is 5:95, 2.5:97.5 or 1.25:98.75. After being mixed at a specific ratio, the two drugs including abamectin and imidacloprid can play a synergistic effect on the toxicity of thrips palmi, so that the effect on efficiently preventing and treating the thrips palmi is achieved. In addition, the two drugs are matched to be used, so that the use concentrations of the drugs can be reduced, furthermore, the cost can be reduced, and most importantly, the hazards to plants can be reduced.
Description
Technical field
The present invention relates to technical field of pesticide, specifically disclose a kind of pharmaceutical composition preventing and treating yellow thrips.
Background technology
Yellow thrips belongs to thrips, Thripidae, and original name, palm thrips, saves melon the most seriously, so also known as yellow thrips, melon thrips because it endangers.In addition, some places are also referred to as pale brown thrips, southern golden thistle horse.Yellow thrips, at south China generation especially severe, if take measures not in time, can cause yield of vegetables to subtract greatly or without results.As in Guangdong Province since the eighties in 20th century, yellow thrips harm increase the weight of year by year; The nineties becomes disastrous insect in Zhejiang, and within 1993,6-9 month yellow thrips breaks out greatly, and the vegetables such as serious harm Solanaceae, Curcurbitaceae, pulse family, cause these vegetables in succession withered; Also there is the report of harm in Guangxi, Hunan, Hubei, Henan, Jiangsu, Shanghai, Shandong etc.In recent years, along with the continuous expansion of greenhouse culture area, the generation of damage by disease and insect in greenhouse is also more and more serious, and yellow thrips has become one of 4 class Main Greenhouse vegetable-crop pest-insects (aphid, aleyrodid, thrips and mite class).The prevention and controls of yellow thrips has cultural control, physical control and chemical control.When population density on blade reaches adult 5.3-10.6 head/sheet, with controls such as 20% imidacloprid soluble dense dose 10-15 gram/acre, Yamanjing 1000 times of liquid or 1500 times of liquid of good winter in year, the precious missible oil of 40% seven-star 500 times of liquid.Because vegetables are to the particular/special requirement of chemical control, the chemical agent being applicable to yellow thrips control is not a lot.Avermectin and Imidacloprid belong to low-residual medicament, and how also rarely known by the people these two kinds of medicaments are to the complex role of yellow thrips.
Summary of the invention
The present invention, in order to overcome in prior art the defect of the medicine lacking effectively control Meloidogyne incognita, provides a kind of pharmaceutical composition of high-efficiency prevention and control yellow thrips.
To achieve these goals, the present invention is achieved by the following technical programs:
Prevent and treat a pharmaceutical composition for yellow thrips, comprise Avermectin and Imidacloprid, the mixture volume ratio of described Avermectin and the former medicine of Imidacloprid is 5:95,2.5:97.5,1.25:98.75.
The present invention found through experiments, Avermectin and Imidacloprid have yellow thrips separately certain murders effect, but if both mixed according to specific ratio, can have the effect of Synergistic, if but mix not in accordance with this special ratios, the effect of superposition can only be had effect.
Preferably, the mixture volume ratio of described Avermectin and the former medicine of Imidacloprid is 2.5:97.5.The present invention studies discovery, and when the mixture volume ratio of Avermectin and Imidacloprid is 2.5:97.5, both Synergistic results are the most remarkable.
Preferably, the weight percentage of described active ingredient is 1 ~ 40%.
More preferably, the weight percentage of described active ingredient is 5 ~ 25%.
Preferably, described combination dosage form comprises missible oil, microemulsion, aqueous emulsion, suspending agent, wetting powder and water dispersible granules.
Compared with prior art, the present invention has following beneficial effect:
Avermectin and Imidacloprid two kinds of medicines, by the mixing of special ratios, the virulence effect to yellow thrips can be played the effect of Synergistic by the present invention, and from realizing the effect of high-efficiency prevention and control yellow thrips.And, by two kinds of medicines with the use of, the working concentration of medicine can be reduced, not only can reduce costs, the more important thing is the harm that can reduce plant.
Embodiment
Further describe invention thinking of the present invention below in conjunction with specific embodiment, but embodiment does not limit in any form to protection scope of the present invention.Unless stated otherwise, the reagent adopted in embodiment, method and apparatus are the art conventional reagent, method and apparatus.
Unless stated otherwise, the feeds utilized raw material of following examples, reagent and material are commercial.
Yellow thrips used in embodiment for the yellow thrips of examination be 3 age nymph.
Described Avermectin and Imidacloprid are common commercially available prod, and described Avermectin is the former medicine of 95% Avermectin.Imidacloprid is the former medicine of 95% Imidacloprid.
embodiment 1
Prevent and treat a pharmaceutical composition for yellow thrips, be made up of Avermectin and Imidacloprid, the mixture volume ratio of described Avermectin and Imidacloprid is 10:90; Avermectin is the former medicine of 95% Avermectin.Imidacloprid is the former medicine of 95% Imidacloprid.
embodiment 2
Prevent and treat a pharmaceutical composition for yellow thrips, be made up of Avermectin and Imidacloprid, the mixture volume ratio of described Avermectin and Imidacloprid is 5:95; Avermectin is the former medicine of 95% Avermectin.Imidacloprid is the former medicine of 95% Imidacloprid.
embodiment 3
Prevent and treat a pharmaceutical composition for yellow thrips, be made up of Avermectin and Imidacloprid, the mixture volume ratio of described Avermectin and Imidacloprid is 2.5:97.5; Avermectin is the former medicine of 95% Avermectin.Imidacloprid is the former medicine of 95% Imidacloprid.
embodiment 4
Prevent and treat a pharmaceutical composition for yellow thrips, be made up of Avermectin and Imidacloprid, the mixture volume ratio of described Avermectin and Imidacloprid is 1.25:98.75; Avermectin is the former medicine of 95% Avermectin.Imidacloprid is the former medicine of 95% Imidacloprid.
embodiment 5
Prevent and treat a pharmaceutical composition for yellow thrips, be made up of Avermectin and Imidacloprid, the mixture volume ratio of described Avermectin and Imidacloprid is 0.625:99.375; Avermectin is the former medicine of 95% Avermectin.Imidacloprid is the former medicine of 95% Imidacloprid.
embodiment 6
Be used for by the pharmaceutical composition of the formula of different proportion shown in embodiment 1-5 killing the test of yellow thrips 3 nymph in age, experiment number of repetition twice, each concentration repeats 4 times, each repetition 30.
According to trial test result, the concentration gradient following (diluting with pure water) of each process is set:
Avermectin: 1ppm, 2ppm, 4ppm, 8ppm, 16ppm, 32ppm;
Imidacloprid: 5ppm, 10 ppm, 20 ppm, 40 ppm, 80 ppm, 160 ppm;
Embodiment 1-5 is totally 5 mixture concentration: 5ppm, 10 ppm, 20 ppm, 40 ppm, 80 ppm, 160 ppm;
Blank: pure water
Respectively the joint melon blade of fresh clean is immersed about 5 seconds in each testing liquid, shake gently after taking out, the beaker of 600ml is put in time not having the unnecessary globule to continue to ooze, often repeat a beaker, each beaker puts a slice blade, access immediately of the same size 3 age yellow thrips nymph, then seal with white gauze and put into artificial incubator breeding observing.Often process and repeat for 4 times, often repeat 30 thrips nymphs.
Data survey and statistical analysis: process latter 48 hours and check and try worm death condition, stiff for death standard with thrips.48 hours remaining borer populations alive of " Invest, Then Investigate ", investigate twice altogether.
Data statistic analysis: adopt probit analysis.By DPS data handling system, concentration, be input to relevant position for examination borer population and dead borer population three item number certificate, and by corresponding operating, DPS software systems can calculate the corrected mortality of each concentration for the treatment of, dead probit value, LC automatically
50, LC
90,the linear regression equation of log concentration (x) and dead probit value (y) and chi-square value, confidence interval etc.
The co-toxicity coefficient (CTC value) of each mixture is calculated according to the abundant method of Sun Yun.
Relative virus force index=
× 100
Co-toxicity coefficient=
× 100
As with the former medicine of 95% Avermectin for standard agent (toxicity index is for 100), then the relative virus force index of other medicament or mixture can correspondingly calculate; Theoretical toxicity index is then the sum of products of each single dose toxicity index and each proportion in mixture in mixture.Refer to table 1.
According to the abundant theory of Sun Yun, after several single dose mixture, if its co-toxicity coefficient is between 80-120, represent that the effect of this built agent is added by each single dose to form; If co-toxicity coefficient is less than 80, then represent there is antagonism between each single dose; If co-toxicity coefficient is greater than 120, then represent that mixed agent has obvious synergistic effect.
Table 1 Avermectin and Imidacloprid are to the Toxicity Determination result of yellow thrips
Avermectin and the Toxicity Determination of Imidacloprid to yellow thrips the results are shown in Table 1, as can be seen from Table 1: by comparing the toxicity test of Avermectin and Imidacloprid 5 different ratio and co-toxicity coefficient in indoor, specify that the optimum proportioning scope of these two medicaments is Avermectin 0.625-2.5, Imidacloprid is 97.5-99.375.Mixed ratio with 2.5:97.5 in this test shows the highest synergistic effect.
Claims (5)
1. prevent and treat a pharmaceutical composition for yellow thrips, it is characterized in that, comprise Avermectin and Imidacloprid, the mixture volume ratio of described Avermectin and the former medicine of Imidacloprid is 5:95,2.5:97.5,1.25:98.75.
2. the pharmaceutical composition of control yellow thrips according to claim 1, is characterized in that, the mixture volume ratio of described Avermectin and the former medicine of Imidacloprid is 2.5:97.5.
3. the pharmaceutical composition of control yellow thrips according to claim 1 and 2, is characterized in that, the weight percentage of described active ingredient is 1 ~ 40%.
4. composition according to claim 3, is characterized in that, the weight percentage of described active ingredient is 5 ~ 25%.
5. composition according to claim 1 and 2, is characterized in that, described combination dosage form comprises missible oil, microemulsion, aqueous emulsion, suspending agent, wetting powder and water dispersible granules.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410701429.3A CN104488947A (en) | 2014-11-28 | 2014-11-28 | Pharmaceutical composition for preventing and treating thrips palmi |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410701429.3A CN104488947A (en) | 2014-11-28 | 2014-11-28 | Pharmaceutical composition for preventing and treating thrips palmi |
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| CN104488947A true CN104488947A (en) | 2015-04-08 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016165641A1 (en) * | 2015-04-16 | 2016-10-20 | Rotam Agrochem International Company Limited | Submicron imidacloprid and abamectin compositions |
| GB2541374A (en) * | 2015-08-11 | 2017-02-22 | Rotam Agrochem Int Co Ltd | Synergistic insecticidal composition |
| CN107771849A (en) * | 2016-08-29 | 2018-03-09 | 四川利尔作物科学有限公司 | Seed treatment composition and its application |
| GB2576125A (en) * | 2015-08-11 | 2020-02-05 | Rotam Agrochem Int Co Ltd | Synergistic insecticidal composition |
| CN112425606A (en) * | 2019-08-26 | 2021-03-02 | 北京市农林科学院 | Insecticidal composition for synergistic control of Aphis vinosa |
-
2014
- 2014-11-28 CN CN201410701429.3A patent/CN104488947A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016165641A1 (en) * | 2015-04-16 | 2016-10-20 | Rotam Agrochem International Company Limited | Submicron imidacloprid and abamectin compositions |
| GB2541374A (en) * | 2015-08-11 | 2017-02-22 | Rotam Agrochem Int Co Ltd | Synergistic insecticidal composition |
| GB2576125A (en) * | 2015-08-11 | 2020-02-05 | Rotam Agrochem Int Co Ltd | Synergistic insecticidal composition |
| GB2541374B (en) * | 2015-08-11 | 2020-04-22 | Rotam Agrochem Int Co Ltd | Synergistic insecticidal composition |
| GB2576125B (en) * | 2015-08-11 | 2020-04-29 | Rotam Agrochem Int Co Ltd | Synergistic insecticidal composition |
| CN107771849A (en) * | 2016-08-29 | 2018-03-09 | 四川利尔作物科学有限公司 | Seed treatment composition and its application |
| CN112425606A (en) * | 2019-08-26 | 2021-03-02 | 北京市农林科学院 | Insecticidal composition for synergistic control of Aphis vinosa |
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Application publication date: 20150408 |