CN104474429B - It is a kind of that there is the Chinese medicine preparation for improving failure of memory function - Google Patents

It is a kind of that there is the Chinese medicine preparation for improving failure of memory function Download PDF

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CN104474429B
CN104474429B CN201410838890.3A CN201410838890A CN104474429B CN 104474429 B CN104474429 B CN 104474429B CN 201410838890 A CN201410838890 A CN 201410838890A CN 104474429 B CN104474429 B CN 104474429B
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jujube
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kernel
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CN104474429A (en
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贾孝荣
王新本
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LANZHOU GUCHI BIOLOGICAL TECHNOLOGY Co Ltd
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Abstract

The invention provides a kind of traditional Chinese medicine health care preparation for having and improving failure of memory function, is mainly used in the improvement and medical treatment of senile dementia, belongs to Chinese medicine health-care field.The present invention is using rose, light wheat, sealwort, Chinese yam, fructus alpiniae oxyphyllae, PORIA ALBA, jujube, jujube kernel, arillus longan, the fruit of Chinese wolfberry, mulberry fruit, walnut kernel, lotus seeds as raw material, and by promoting qi circulation and removing obstruction in the collateral, yin-nourishing is with all worries set aside, Qi-benefiting and heart-nourishing, enriches blood nourshing kidney to realize the improvement to human body failure of memory.Clinical test shows that senile dementia tool is improved significantly Chinese medicine preparation of the present invention and medical treatment acts on.Clinical data also confirms that medicine of the present invention also has good opsonic action for the memory of a middle-aged person, study idea, the decline of intention power.In addition, each bulk drug uses the Chinese medicine of integration of drinking and medicinal herbs in pharmaceutical preparation of the present invention, thus have health care function concurrently.

Description

It is a kind of that there is the Chinese medicine preparation for improving failure of memory function
Technical field
The invention belongs to Chinese medicine health-care technical field, is related to a kind of Chinese medicine system for having and improving human body failure of memory function Agent, it is mainly used in the improvement and medical treatment of senile dementia.
Background technology
Senile dementia, it is called Alzheimer disease(AD), it is a kind of nervous system of the progress sexual development of onset concealment Degenerative disease.Clinically with memory disorders, aphasia, appraxia, agnosia, the infringement of visual space technical ability, perform function obstacle and people The performance of the generalized dementia such as lattice and behavior change is characterized, and the cause of disease is unknown so far.It is mainly shown as decrease of cognitive function, psychosis Shape and behavior disorder, activity of daily living are gradually reduced.It is divided into three according to the deterioration degree of cognitive ability and physical function Period:First stage, it is the mild dementia phase, shows as hypomnesia, ecmnesia is protruded;Judgement declines, and patient is not Event can be analyzed, thought deeply, be judged, it is difficult to handle the problem of complicated;Although remaining to do a little known routine works, New things is but shown ignorantly to be difficult to resolve, apathy, excitation, often has suspicious once in a while;Time of occurrence disorientation, to residing Place and personage can make orientation, difficult, the visual space ability of labyrinth is oriented to residing geographical position;Speech vocabulary Few, name is difficult.Second stage, it is the moderate dementia phase, shows as far and near memory and be badly damaged, the visual space ability of simple structure Decline, time, disturbance of orientation to place;Process problem, distinguish things similitude and discrepancy in terms of have serious infringement;Can not It is independent to carry out outdoor activity, wearing the clothes, personal hygiene and want help in terms of keeping personal appearance;Calculating can not;Occur each Kind nervous symptoms, it is seen that aphasia, appraxia and agnosia;Emotion is changed into irritable uneasy from indifferent, often walks about and does not stop, it is seen that the urinary incontinence. Phase III, is severe dementia phase, and patient has been completely dependent on caregiver, serious memory loss, only deposits the memory of fragment;Day Often it can't take care of oneself, gatism, presentation is kept silent, rigid limbs, and visible pyramidal sign of having a medical check-up is positive, has and holds by force, gropes With the primary reflection such as suck.
At present, the inferior health problem such as senile dementia is increasingly annoying the people of modern society, on such issues that It is individually more using kidney-nourishing mends marrow medicine generally to administer, and the present invention is quite different, by using integration of drinking and medicinal herbs raw material and has Promoting qi circulation and removing obstruction in the collateral, yin-nourishing are with all worries set aside, Qi-benefiting and heart-nourishing, enrich blood and contain the prescription of heart function to realize that comprehensive improvement to senile dementia is made With.
The content of the invention
The purpose of the present invention is the problem of being directed to senile dementia, there is provided one kind has improvement human body failure of memory function Chinese medicine preparation.
The Chinese medicine preparation of the present invention is with rose, light wheat, sealwort, Chinese yam, fructus alpiniae oxyphyllae, PORIA ALBA, jujube, jujube kernel, dragon Eye meat, the fruit of Chinese wolfberry, mulberry fruit, walnut kernel, lotus seeds are that raw material carries out compatibility, and the effect of making each medicine produces collaboration, gather promoting the circulation of qi solution altogether Strongly fragrant, yin-nourishing is set aside all worries, Qi-benefiting and heart-nourishing, the function for the culvert heart of enriching blood, so as to realize the improvement and medical treatment effect to human body failure of memory.
Rose, sweet and slightly bitter taste, slightly warm in nature, Return liver, spleen, stomach;Function:Regulating the flow of vital energy Xie Yu, and blood dissipate the stasis of blood.The present invention is with rose Rare flower is monarch drug in a prescription, and promoting the circulation of qi is with intelligence development, Xie Yu with intelligence development, promoting blood circulation with intelligence development.
Light wheat, it is sweet, it is cool;Effect:Only abnormal sweating, mental-tranquilization.The present invention is using light wheat as ministerial drug, by holding back the moon with benefit Intelligence, nourishing heart with intelligence development, calm the nerves with intelligence development.
Sealwort, it is sweet, put down;Returns spleen, lung, kidney channel;Boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney-nourishing.Chinese yam, it is sweet, flat;Returns spleen, lung, kidney Through;Function:Tonifying spleen nourishing the stomach, engender liquid and benefic lung, the puckery essence of kidney tonifying.For the present invention using sealwort, Chinese yam as adjutant, logical upper, middle and lower three of controlling is burnt, makes Monarch-minister drug intelligence development ability is ensured.
Fructus alpiniae oxyphyllae, pungent, temperature;Enter spleen, kidney channel;Warm spleen, warm up kidney, solid and gas, puckery essence.PORIA ALBA, it is sweet, light, it is mild-natured;The thoughts of returning home, spleen, Lung, kidney channel;Eliminating dampness and diuresis, strengthening the spleen and stomach, antitoxic heart-soothing and sedative.Jujube, sweet, temperature;Returns spleen, stomach;Tonifying middle-Jiao and Qi, nourishing blood and tranquilization.Jujube Benevolence, it is sweet, sour, put down;Return liver, courage, the heart channel of Hang-Shaoyin;Effect:Tonifying liver, calming heart, arrest sweating, promote the production of body fluid.Arillus longan, sweet, temperature;The thoughts of returning home, the spleen channel;Work( Effect:Tonifying heart and spleen, nourishing blood and tranquilization.The fruit of Chinese wolfberry, it is sweet, put down;Enter liver and kidney channel;Effect:Nourshing kidney, moistening lung, tonifying liver, improving eyesight.Mulberry fruit, sweet, Acid, tremble with fear;The thoughts of returning home, liver and kidney channel;Effect:Enrich blood enriching yin, fluid dryness.Walnut kernel, sweet, temperature;Return kidney channel, lung, large intestine channel;Effect: Kidney tonifying warm lung, relaxes bowel.Lotus seeds, it is sweet, puckery, put down;Returns spleen, kidney, the heart channel of Hang-Shaoyin;Function:Tonifying spleen and stopping diarrhea, the puckery essence of kidney-nourishing, mental-tranquilization. The present invention uses tradition using fructus alpiniae oxyphyllae, PORIA ALBA, jujube, jujube kernel, arillus longan, the fruit of Chinese wolfberry, mulberry fruit, walnut kernel, lotus seeds as medicine is made Intelligence development Chinese herbal medicine strengthen intelligence development functions, and improve supplementing qi and nourishing yin, enrich blood nourshing kidney to realize.
Each raw material of Chinese medicine preparation of the present invention is matched by following parts by weight:Rose 25-40 parts, light wheat 18-25 Part, sealwort 10-18 parts, Chinese yam 10-18 parts, fructus alpiniae oxyphyllae 4-10 parts, PORIA ALBA 4-10 parts, jujube 4-10 parts, jujube kernel 4-10 parts, dragon Eye meat 4-10 parts, fruit of Chinese wolfberry 4-10 parts, mulberry fruit 4-10 parts, walnut kernel 4-10 parts, lotus seeds 4-10 parts.
Optimum ratio:Rose 30-35 parts, light wheat 20-24 parts, sealwort 13-16 parts, Chinese yam 13-16 parts, fructus alpiniae oxyphyllae 6- 8 parts, PORIA ALBA 6-8 parts, jujube 6-8 parts, jujube kernel 6-8 parts, arillus longan 6-8 parts, fruit of Chinese wolfberry 6-8 parts, mulberry fruit 6-8 parts, walnut kernel 6-8 parts, lotus seeds 6-8 parts.
Optimum proportioning:30 parts of rose, 23 parts of light wheat, 15 parts of sealwort, 15 parts of Chinese yam, 7.5 parts of fructus alpiniae oxyphyllae, PORIA ALBA 7.5 parts, 7.5 parts of jujube, 7.5 parts of jujube kernel, 7.5 parts of arillus longan, 7.5 parts of the fruit of Chinese wolfberry, 7.5 parts of mulberry fruit, 7.5 parts of walnut kernel, lotus seeds 7.5 part.
The Chinese medicine preparation of the present invention can be prepared into various oral preparations by the common process and auxiliary material of pharmacy.Such as capsule Agent, tablet, granule, powder, pill(Including the water-bindered pill, honeyed bolus, dragee, capsule and pill, enteric coated pill or dripping pill)Or oral liquid.
Below by taking senile dementia as an example, the effect for improving failure of memory to medicine of the present invention by clinical data is carried out Explanation.
1st, the object of observation:It is diagnosed as patients of senile dementia function 120, wherein first stage, second stage, the 3rd rank Each 40 of patient of section.Men and women has, and the age is 70-88 year.
2nd, treatment method:Granules medicine of the present invention(13 fructus alpiniae oxyphyllae tea).Specification:6g/ bags, 30 bags/box.Usage is used Amount:Sooner or later each one bag, warm water is directly taken after mixing it with water.The course for the treatment of:Cycle in March 1, the cycle of overview 3.
3rd, therapeutic effect criterion:
First stage:Recovery from illness:Memory, judgement and the normal person of same age level approach.Effectively:Memory, sentence Cutting capacity has obvious improvement, has the ability lived on one's own life and taken action.It is invalid:Memory, judgement and ability to act Do not improve significantly than before.
Second stage:Recovery from illness:Memory, judgement and the normal person of same age level approach.Effectively:Symptom is by moderate It is effective that dementia, which is changed into mild dementia,.It is invalid:Memory, judgement and ability to act do not improve significantly.
Phase III:Recovery from illness:Memory, judgement and the normal person of same age level approach.Effectively:Symptom is by severe Dementia is changed into moderate dementia.It is invalid:Memory, judgement and ability to act do not improve significantly than before.
4th, result is observed:Clinical observation, which is shown, is shown in Table 1.Wherein, the effective percentage of mild dementia is 95%, and moderate dementia has Efficiency is 77.5%, and the effective percentage of severe dementia is 57.5%.
Clinical test shows that senile dementia tool is improved significantly Chinese medicine preparation of the present invention and medical treatment acts on.It is clinical Data also confirms that medicine of the present invention also has good opsonic action for the memory of a middle-aged person, study idea, the decline of intention power. In addition, each bulk drug uses the Chinese medicine of integration of drinking and medicinal herbs in pharmaceutical preparation of the present invention, thus have the effect of health concurrently.
Embodiment
The prescription of medicine of the present invention and its preparation are described further below by specific embodiment.
The preparation of embodiment 1, granules medicine
Raw material proportioning:30 parts of rose, 23 parts of light wheat, 15 parts of sealwort, 15 parts of Chinese yam, 7.5 parts of fructus alpiniae oxyphyllae, PORIA ALBA 7.5 parts, 7.5 parts of jujube, 7.5 parts of jujube kernel, 7.5 parts of arillus longan, 7.5 parts of the fruit of Chinese wolfberry, 7.5 parts of mulberry fruit, 7.5 parts of walnut kernel, lotus seeds 7.5 part.
Preparation technology:The common process of granule is prepared by pharmacy and auxiliary material is prepared;Specification:6g/ bags.
Usage and dosage:Sooner or later each one bag, warm water is directly taken after mixing it with water;The course for the treatment of:Cycle in March 1, the cycle of overview 3.
The preparation of embodiment 2, capsule medicine
Raw material proportioning:35 parts of rose, 24 parts of light wheat, 16 parts of sealwort, 16 parts of Chinese yam, 8 parts of fructus alpiniae oxyphyllae, 8 parts of PORIA ALBA, 8 parts of jujube, 8 parts of jujube kernel, 8 parts of arillus longan, 8 parts of the fruit of Chinese wolfberry, 8 parts of mulberry fruit, 8 parts of walnut, 8 parts of lotus seeds.
Preparation technology:The common process of capsule is prepared by pharmacy and auxiliary material is prepared;Specification:0.3g/ grains.
Usage and dosage:Sooner or later each 0.9g, warm water are directly taken after mixing it with water;The course for the treatment of:Cycle in March 1, the cycle of overview 3.
The preparation of embodiment 3, tablet medicine
Raw material proportioning:30 parts of rose, 20 parts of light wheat, 13 parts of sealwort, 13 parts of Chinese yam, 6 parts of fructus alpiniae oxyphyllae, 6 parts of PORIA ALBA, 6 parts of jujube, 6 parts of jujube kernel, 6 parts of arillus longan, 6 parts of the fruit of Chinese wolfberry, 6 parts of mulberry fruit, 6 parts of walnut kernel, 6 parts of lotus seeds.
Preparation technology:The common process of tablet is prepared by pharmacy and auxiliary material is prepared;Specification:1.0g/ grain.
Usage and dosage:Sooner or later each 3.0g, warm water are directly taken after mixing it with water;The course for the treatment of:Cycle in March 1, the cycle of overview 3.
The preparation of embodiment 4, pill medicine
Raw material proportioning:25 parts of rose, 18 parts of light wheat, 10 parts of sealwort, 10 parts of Chinese yam, 4 parts of fructus alpiniae oxyphyllae, 4 parts of PORIA ALBA, 4 parts of jujube, 4 parts of jujube kernel, 4 parts of arillus longan, 4 parts of the fruit of Chinese wolfberry, 4 parts of mulberry fruit, 4 parts of walnut kernel, 4 parts of lotus seeds.
Preparation technology:The common process of pill is prepared by pharmacy and auxiliary material is prepared;Specification:0.05g/ bags.
Usage and dosage:Sooner or later each 6.0g, warm water are directly taken after mixing it with water;The course for the treatment of:Cycle in March 1, the cycle of overview 3.
The preparation of embodiment 5, oral medicine liquid of the present invention
Raw material proportioning:40 parts of rose, 25 parts of light wheat, 18 parts of sealwort, 18 parts of Chinese yam, 10 parts of fructus alpiniae oxyphyllae, PORIA ALBA 10 Part, 10 parts of jujube, 10 parts of jujube kernel, 4 parts of arillus longan, 10 parts of the fruit of Chinese wolfberry, 10 parts of mulberry fruit, 10 parts of walnut kernel, 10 parts of lotus seeds.
Preparation technology:The common process of oral liquid is prepared by pharmacy and auxiliary material is prepared.Specification:10ml/ bottles.
Usage and dosage:Sooner or later each 20ml, warm water are directly taken after mixing it with water or directly swallowed;The course for the treatment of:Cycle in March 1, overview 3 Cycle.
In the various embodiments described above, each raw material proportioning is in parts by weight.

Claims (4)

  1. It is with rose, light wheat, sealwort, Chinese yam, benefit 1. a kind of have the traditional Chinese medicine health care preparation for improving failure of memory function Intelligence benevolence, PORIA ALBA, jujube, jujube kernel, arillus longan, the fruit of Chinese wolfberry, mulberry fruit, walnut kernel, lotus seeds are raw material, by the customary adjuvant of pharmacy The oral preparations being prepared into technique;Each raw material is matched by following parts by weight:
    Rose 25-40 parts, light wheat 18-25 parts, sealwort 10-18 parts, Chinese yam 10-18 parts, fructus alpiniae oxyphyllae 4-10 parts, PORIA ALBA 4- 10 parts, jujube 4-10 parts, jujube kernel 4-10 parts, arillus longan 4-10 parts, fruit of Chinese wolfberry 4-10 parts, mulberry fruit 4-10 parts, walnut kernel 4-10 parts, Lotus seeds 4-10 parts.
  2. 2. there is the traditional Chinese medicine health care preparation for improving failure of memory function as claimed in claim 1, it is characterised in that:Each original Material is matched by following parts by weight:
    Rose 30-35 parts, light wheat 20-24 parts, sealwort 13-16 parts, Chinese yam 13-16 parts, fructus alpiniae oxyphyllae 6-8 parts, PORIA ALBA 6-8 Part, jujube 6-8 parts, jujube kernel 6-8 parts, arillus longan 6-8 parts, fruit of Chinese wolfberry 6-8 parts, mulberry fruit 6-8 parts, walnut kernel 6-8 parts, lotus seeds 6-8 Part.
  3. 3. there is the traditional Chinese medicine health care preparation for improving failure of memory function as claimed in claim 1, it is characterised in that:Each original Material is matched by following parts by weight:
    30 parts of rose, 23 parts of light wheat, 15 parts of sealwort, 15 parts of Chinese yam, 7.5 parts of fructus alpiniae oxyphyllae, 7.5 parts of PORIA ALBA, jujube 7.5 Part, 7.5 parts of jujube kernel, 7.5 parts of arillus longan, 7.5 parts of the fruit of Chinese wolfberry, 7.5 parts of mulberry fruit, 7.5 parts of walnut kernel, 7.5 parts of lotus seeds.
  4. 4. there is the traditional Chinese medicine health care preparation for improving failure of memory function as claimed in claim 1, it is characterised in that:It is described for oral administration Preparation is capsule, tablet, granule, pill or oral liquid.
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CN106974285A (en) * 2017-03-31 2017-07-25 江苏康缘药业股份有限公司 A kind of Chinese medicine composition and its application

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