CN104474257A - Preparation for treating acnes - Google Patents
Preparation for treating acnes Download PDFInfo
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- CN104474257A CN104474257A CN201410793409.3A CN201410793409A CN104474257A CN 104474257 A CN104474257 A CN 104474257A CN 201410793409 A CN201410793409 A CN 201410793409A CN 104474257 A CN104474257 A CN 104474257A
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- comedo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
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- Biotechnology (AREA)
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Abstract
The invention discloses a preparation for treating acnes. The preparation is prepared from the following raw materials: 10-20 parts of wild chrysanthemum flower, 10-20 parts of radix ophiopogonis, 10-20 parts of lotus leaves, 10-20 parts of cortex phellodendri, 10-20 parts of scutellaria baicalensis, 20-30 parts of salviae miltiorrhizae, 25-35 parts of sow thistle, 25-35 parts of honeysuckle and 2-4 parts of borneol. The preparation is prepared by the following steps: respectively crushing the dried components with a crusher, and screening by virtue of a sieve of which the sieve pore diameter is 1mm; collecting powder of which the diameter is smaller than 1mm; mixing and enclosing into a sealed glass or stainless steel container; adding 50%-90% ethanol solution according to the ratio of ethanol solution to mixed powder being 1L to (0.1-2)kg; and hermetically soaking for 3-15 days, and filtering with cloth or filter paper, so as to obtain filtrate, namely the preparation for treating acnes. The preparation disclosed by the invention is directly applied on the affected parts of the acnes.
Description
Technical field
The invention belongs to Chinese medicine extract and preparation technique field thereof, relate to a kind of Chinese medicine formula extract---a kind of preparation for the treatment of comedo.
Background technology
Comedo, skin ulcer of drawing well again, is a kind of pilosebaceous chronic inflammatory disease, is apt to occur in face, chest and back, show as blackhead, pimple, pustule, the infringements such as cyst.Primary disease is a kind of multi-pathogenesis disease, often think increasing due to androgen and metabolite thereof, sebaceous gland activity is strengthened, or hair follicle leaks the enhancing of head keratinization process, or its cell membrane densification thickens difficult drop-off, or the rising of sebum Free Fat, or hair follicle endoparasitism seat skin ulcer bacterium acidi propionici, or trace element deficiency etc. in inherited genetic factors and body.
The traditional Chinese medical science is recorded very early to acne, as " case gold mirror surgery heart method " on the books in " disorderly ask vital QI of the body connecting with natural QI opinion " claims primary disease to be " rosacea caused by lung-wind ", this card is formed by lung meridian heat in blood, be apt to occur in face nose, play broken pimple, shape such as broomcorn millet bits red complexion swells and ache, break out white lead juice, the traditional Chinese medical science also has title primary disease to be " acne vulgaris ", " acne vulgaris " or " whelk ", the primary disease cause of disease is that lung qi is unclear outer by wind heat, or eating and drinking without temperance surfeit delicious food savoury, upward steaming of stomach-heat, also can be menoxenia, stasis of blood stagnation-derived fever etc., the traditional Chinese medical science thinks that acne is that interior-heat is flourishing and is subject to caused by ailment said due to cold or exposure outward.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of preparation for the treatment of comedo.
For solving the problems of the technologies described above, the invention provides a kind of preparation for the treatment of comedo, the preparation of described treatment comedo by weight, containing Flos Chrysanthemi Indici 10-20, Radix Ophiopogonis 10-20, Folium Nelumbinis 10-20, Cortex Phellodendri 10-20, Radix Scutellariae 10-20, Radix Salviae Miltiorrhizae 20-30, Herba Sonchi Oleracei 25-35, Flos Lonicerae 25-35, Borneolum Syntheticum 2-4.
The preparation method of the preparation of described treatment comedo comprises the following steps:
1) by weight, by the Flos Chrysanthemi Indici of drying, Radix Ophiopogonis, Folium Nelumbinis, Cortex Phellodendri, Radix Scutellariae, Radix Salviae Miltiorrhizae, Herba Sonchi Oleracei, Flos Lonicerae, Borneolum Syntheticum sieves with sieve diameter 1mm after pulverizing respectively at pulverizer, and raw material diameter being greater than 1mm pulverizes and sieves again, collects the powder that diameter is less than 1mm;
2) sealable glass or rustless steel container is loaded after the diameter of above-mentioned whole component being less than the powder mixing of 1mm, the alcoholic solution that concentration is 50-90% is added according to the ratio of often liter of alcoholic solution 0.1-2 kilograms of mixed-powders, sealing immersion is after 10-15 days, with cloth or filter paper filtering, obtain the preparation that filtrate is treatment comedo.
Said process is summarised as:
L, raw material pulverizing: by the dry Chinese medicine of above-mentioned whole component respectively at pulverizer grinding and sieving (sieve diameter 1mm), collect the powder that diameter is less than 1mm; Raw material diameter being greater than 1mm is again pulverized 1 time and sieves equally, for soaking or extracting;
2, extract: the important mixing of above-mentioned pulverizing is loaded sealable glass or rustless steel container, the alcoholic solution that concentration is 50-90% is added according to the ratio of often liter of alcoholic solution 0.1-2 kilograms of mixed-powders, sealing immersion is after 10-15 days, with cloth or filter paper filtering, obtain the preparation that filtrate is treatment comedo;
The present invention treats the treatment processing method of the preparation of comedo: with cotton swab, said extracted liquid is directly coated in affected part, every day is coated with 1-3 times.3 days 1 courses for the treatment of.
The present invention is from the feature of above-mentioned Chinese medicine extract treatment comedo, and one is that curative effect is fast, processes latter 12 hours visual effects; Two is that therapeutic effect is remarkable, the treated effect (naked eyes can find out that affected part swelling obviously reduces, and the process pox that the pain of patient, gargalesthesia obviously reduce is counted and accounted for total ratio processing pox and count) 67-94% of 1 course for the treatment of; Three is have no side effect.
Flos Chrysanthemi Indici: bitter in the mouth, pungent, is slightly cold; Return lung, Liver Channel.There is effect of heat-clearing and toxic substances removing; For the card of carbuncle, furunculosis, laryngopharynx swelling and pain, wind-fire acute conjunctivitis, skin pruritus.
Radix Ophiopogonis: sweet in the mouth, micro-hardship, be slightly cold; GUIXIN, lung, stomach warp.There is YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire; For dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.
Folium Nelumbinis: bitter in the mouth, puckery, property is put down; GUIXIN, liver, spleen channel.There is clearing away summer-heat and eliminating dampness, effect of hemostasis; For heatstroke, hemoptysis, metrorrhagia.
Cortex Phellodendri: bitter in the mouth, cold; Return kidney, bladder, large intestine channel.There is heat clearing and damp drying.Eliminating fire and detoxication, effect of reducing the asthenic fever; For damp-heat dysentery, jaundice, leukorrhagia, pathopyretic ulcer, eczema, fever due to yin deficiency.
Radix Scutellariae: bitter in the mouth, cold; Return lung, gallbladder, spleen, large intestine, small intestine meridian.There is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive effect; For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Radix Salviae Miltiorrhizae: bitter in the mouth, is slightly cold; GUIXIN, pericardium, Liver Channel.There is blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle, effect of nourishing blood to tranquillize the mind; For menoxenia, trusted subordinate pain , lumps in the chest and abdomen, beriberoid pyretic arthralgia, skin infection swells and ache, and agitation is insomnia, cardiopalmus, insomnia.
Herba Sonchi Oleracei: bitter in the mouth, cold in nature; GUIXIN, spleen, stomach, large intestine channel; There is heat-clearing and toxic substances removing; Effect of cooling blood for hemostasis; Scorching for intestinal; Dysentery; Jaundice; Stranguria; Laryngopharynx swelling and pain; Carbuncle pyogenic infections from tumour or sore; Mastitis; Hemorrhoid complicated by anal fistula; Spit blood; Epistaxis; Spitting of blood; Hematuria; Have blood in stool; Metrorrhagia.
Flos Lonicerae: sweet in the mouth, cold; Return lung, the heart, stomach, large intestine channel.There is heat-clearing and toxic substances removing, effect of dispelling wind and heat pathogens; For affection due to external wind and heat, epidemic febrile disease is generated heat, carbuncle skin infection, laryngopharynx swelling and pain, pyretic toxicity dysentery.
Borneolum Syntheticum: acrid in the mouth, hardship, be slightly cold; GUIXIN, spleen, lung hydrocarbon.There is refreshment of having one's ideas straightened out, effect of clearing away heat to alleviate pain; For closing coma for key, skin infection, laryngopharynx swelling and pain, aphtha of the mouth and tongue.
Detailed description of the invention
Treat a preparation for comedo, Chinese medicinal components proportioning and operating procedure as follows:
1), Chinese medicinal components and proportioning (weight portion) are: Flos Chrysanthemi Indici 15, Radix Ophiopogonis 15, Folium Nelumbinis 15, Cortex Phellodendri 15, Radix Scutellariae 15; Radix Salviae Miltiorrhizae 25, Herba Sonchi Oleracei 30, Flos Lonicerae 30, Borneolum Syntheticum 3;
2), raw material pulverizing: by the Chinese medicine of above-mentioned drying respectively at pulverizer grinding and sieving (sieve diameter 1mm), collect the powder that diameter is less than 1mm; Raw material diameter being greater than 1mm is again pulverized 1 time and sieves equally, for soaking or extracting;
3), extract: the Traditional Chinese drug mixture of above-mentioned pulverizing is loaded sealable glass or rustless steel container, add with the ratio (namely often liter of alcoholic solution adds 0.3 kilogram and mixes Chinese medicinal powder) of alcoholic solution 1/3 kg/liter the alcoholic solution that concentration is 60-70% (v/v), sealing immersion 10 days according to powder.Filter with cloth, collect filtrate as preparation;
4), compliance test result: with cotton swab, said extracted liquid formulation is directly coated in affected part, is coated with 2 every day, for three days on end.Therapeutic effect: trier 10 people (man, each 5 people of female, age 16-24 year) coprocessing affected part 40 place, after 1 course for the treatment of, 36 affected part, place swelling obviously reduce, and wherein 30 place's symptoms disappear completely, and pain, the gargalesthesia of patient obviously reduce, treated effect 92.5%.
What more than enumerate is only a specific embodiment of the present invention.Obviously, the invention is not restricted to above embodiment, many distortion can also be had.All distortion that those of ordinary skill in the art can directly derive from content disclosed by the invention or associate, all should think protection scope of the present invention.
Claims (1)
1. treat a preparation for comedo, it is characterized in that: described treatment comedo preparation by weight, containing Flos Chrysanthemi Indici 10-20, Radix Ophiopogonis 10-20, Folium Nelumbinis 10-20, Cortex Phellodendri 10-20, Radix Scutellariae 10-20, Radix Salviae Miltiorrhizae 20-30, Herba Sonchi Oleracei 25-35, Flos Lonicerae 25-35, Borneolum Syntheticum 2-4.
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CN201410793409.3A CN104474257A (en) | 2014-12-20 | 2014-12-20 | Preparation for treating acnes |
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CN201410793409.3A CN104474257A (en) | 2014-12-20 | 2014-12-20 | Preparation for treating acnes |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107529438A (en) * | 2017-08-30 | 2018-01-02 | 王继跃 | A kind of Chinese medicine preparation for treating acne and preparation method thereof |
Citations (4)
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US20050037098A1 (en) * | 2003-08-11 | 2005-02-17 | I-Hung Chu | Vapor fraction from seeds of glycine max (L.)Merr. and composition thereof |
CN1911331A (en) * | 2006-08-29 | 2007-02-14 | 浙江大学 | Medicine prepn. for treating acne, and its prepn. method |
CN102416065A (en) * | 2011-12-14 | 2012-04-18 | 曹莹莹 | Chinese medicinal embrocation for treating acnes |
CN102793785A (en) * | 2011-07-19 | 2012-11-28 | 上海市中医医院 | Chinese rhubarb-baical skullcap root-amur corktree bark itching-relieving liniment and preparation method thereof |
-
2014
- 2014-12-20 CN CN201410793409.3A patent/CN104474257A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050037098A1 (en) * | 2003-08-11 | 2005-02-17 | I-Hung Chu | Vapor fraction from seeds of glycine max (L.)Merr. and composition thereof |
CN1911331A (en) * | 2006-08-29 | 2007-02-14 | 浙江大学 | Medicine prepn. for treating acne, and its prepn. method |
CN102793785A (en) * | 2011-07-19 | 2012-11-28 | 上海市中医医院 | Chinese rhubarb-baical skullcap root-amur corktree bark itching-relieving liniment and preparation method thereof |
CN102416065A (en) * | 2011-12-14 | 2012-04-18 | 曹莹莹 | Chinese medicinal embrocation for treating acnes |
Non-Patent Citations (2)
Title |
---|
刘刚: "《常见皮肤病的中西医结合治疗学》", 31 March 2014 * |
徐明等: "五味消毒饮加减配合颠倒散外用治疗脓疱性痤疮", 《中国中西医结合皮肤性病学杂志》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107529438A (en) * | 2017-08-30 | 2018-01-02 | 王继跃 | A kind of Chinese medicine preparation for treating acne and preparation method thereof |
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