CN104474175A - TCM (traditional Chinese medicine) preparation for treatment of red-head diseases of loaches - Google Patents

TCM (traditional Chinese medicine) preparation for treatment of red-head diseases of loaches Download PDF

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Publication number
CN104474175A
CN104474175A CN201410700848.5A CN201410700848A CN104474175A CN 104474175 A CN104474175 A CN 104474175A CN 201410700848 A CN201410700848 A CN 201410700848A CN 104474175 A CN104474175 A CN 104474175A
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gram
grams
chinese medicine
preparation
tcm
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李锡欢
董学龙
李志见
崔红伟
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SHANDONG JIASHUO AGRICULTURAL DEVELOPMENT Co Ltd
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SHANDONG JIASHUO AGRICULTURAL DEVELOPMENT Co Ltd
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Priority to CN201410700848.5A priority Critical patent/CN104474175A/en
Publication of CN104474175A publication Critical patent/CN104474175A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
    • A61K36/515—Gentiana
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/754—Evodia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage

Abstract

The invention relates to a TCM (traditional Chinese medicine) preparation for the treatment of loaches, and particularly relates to a TCM (traditional Chinese medicine) preparation for the treatment of red-head diseases of loaches. The TCM preparation is prepared from the following traditional Chinese medicines in parts by weight: fructus forsythiae, lonicera japonica, fructus gardeniae, rhizoma belamcandae, evodia rutaecarpa, pericarpium granati, calamendiol, gallnut, humifuse euphorbia herb, juncus pith, and gentiana scabra bge. The TCM preparation disclosed by the invention has the beneficial effects that Chinese herbal medicines have the characteristics of wide sources, low toxicity, small side effect, difficult production of drug resistance, and the like, and in recent years, Chinese herbal medicines are more applied in aquaculture; and active ingredients such as various alkaloids, volatile oil and organic acids in Chinese herbal medicines both have a bactericidal effect and an immune function, so that the TCM preparation can improve the immunity of aquatic animals.

Description

The Chinese medicine for the treatment of Misgurni anguillicaudati red head disease of Pseudobagrus
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of Misgurni anguillicaudati, particularly a kind of Chinese medicine for the treatment of Misgurni anguillicaudati red head disease of Pseudobagrus.
Background technology
Misgurni anguillicaudati " red head disease of Pseudobagrus " is common disease in loach breeding process in recent years.This sick mortality rate is high, and treatment difficulty is large." red head disease of Pseudobagrus " of Lianyungang of Jiangsu Misgurni anguillicaudati in this year is much harder than ever, and raiser but can only have no way out to this.Misgurni anguillicaudati red head disease of Pseudobagrus main manifestations is the crown " Herba Duchesneae Indicae " (congestive symptom).Their early stage, sick fish body surface, without obvious clinical manifestation, examines visible sick fish body colour thin out.Morbidity middle and late stage, sick fish head top is congested, hemorrhage, the crown upwards swell form pustule, skin of head festers, time serious, crown perforation, splits, is even eaten hollow by skull, forms a long and narrow cavity, exposes cerebral tissue.The serious symptom also having fin rubescent.Dissect visible abdominal cavity and have pale yellow transparent shape liquid, occur haemolysis individually; Liver enlargement, congested degeneration, liver khaki is matt, has petechia or ecchymosis; Bile color is thin out or become blue; Spleen and renomegaly hyperemia; Stomach expands, and coat of the stomach hyperemia is heavier, and gastric is without food or have a small amount of food, has individually stomach seeping phenomenon; Intestinal walls is rubescent, and intestinal mucosa comes off, and cuts off intestinal visible yellow color extract shape liquid.It is the principal character of red head disease of Pseudobagrus that head " splits "." split head " and be the symptom in latter stage of morbidity, but be not that " splitting head " symptom all can appear in the Misgurni anguillicaudati that red head disease of Pseudobagrus occurs, majority does not develop into " splitting head " stage is with regard to dead.Through observing, when red head disease of Pseudobagrus symptom not yet occurs, the internal organs checking normal Misgurni anguillicaudati particularly liver have slight damage in various degree and characteristic of disease, and main manifestations is that the quality of liver becomes fragile, nonelastic, has slight variable color.Along with disease, sick fish appetite subtracts lower limb, and peel off solely trip, have the water surface do intermittent mad trip or long period head-up, tail is vertically suspended from water down, and carrys out back rotation.
Summary of the invention
Object of the present invention is exactly in view of the foregoing defects the prior art has, provides a kind of Chinese medicine for the treatment of Misgurni anguillicaudati red head disease of Pseudobagrus, and formula is reasonable, and preparation method is simple, and expense is low, has no side effect, and Therapeutic Method is convenient; Chinese herbal medicine has the features such as source is wide, toxicity is low, side effect is little, not easily develop immunity to drugs.
Its technical scheme is made up of the Chinese medicine of following weight portion:
Fructus Forsythiae 450-550 gram, Flos Lonicerae 450-550 gram, Fructus Gardeniae 450-550 gram, Rhizoma Belamcandae 450-550 gram, Fructus Evodiae 450-550 gram, Pericarpium Granati 450-550 gram, Rhizoma Acori Graminei 450-550 gram, Galla Chinensis 450-550 gram, Herba Euphorbiae Humifusae 450-550 gram, Medulla Junci 450-550 gram, Radix Gentianae 450-550 gram.
Preferably, be made up of the Chinese medicine of following weight portion:
Fructus Forsythiae 425-525 gram, Flos Lonicerae 425-525 gram, Fructus Gardeniae 425-525 gram, Rhizoma Belamcandae 425-525 gram, Fructus Evodiae 425-525 gram, Pericarpium Granati 425-525 gram, Rhizoma Acori Graminei 425-525 gram, Galla Chinensis 425-525 gram, Herba Euphorbiae Humifusae 425-525 gram, Medulla Junci 425-525 gram, Radix Gentianae 425-525 gram.
Preferably, be made up of the Chinese medicine of following weight portion:
Fructus Forsythiae 500 grams, Flos Lonicerae 500 grams, Fructus Gardeniae 500 grams, Rhizoma Belamcandae 500 grams, Fructus Evodiae 500 grams, Pericarpium Granati 500 grams, Rhizoma Acori Graminei 500 grams, Galla Chinensis 500 grams, Herba Euphorbiae Humifusae 500 grams, Medulla Junci 500 grams, Radix Gentianae 500 grams.
Mechanism of the present invention is as follows:
Fructus Forsythiae: Fructus Forsythiae, another name: Hemerocallis citrina Baroni bar, Huang Shoudan, green grass or young crops stick up, fall to sticking up, Huang Qidan, Hemerocallis citrina Baroni bar; Nature and flavor are bitter, cool, nontoxic.Enter the heart, liver, gallbladder meridian.Effect: heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Flos Lonicerae: another name: Caulis Lonicerae, silvernine, two color flower rattans, two precious rattans, right-hand rotation rattan, sub-Radix seu Caulis fici Martinii, Aicis galericulata rattan, Flos Lonicerae.Cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.
Fructus Gardeniae: another name: Yellow Fructus Gardeniae, Fructus Gardeniae, white toad are the fruits of Maguireothamnus speciosus Fructus Gardeniae.Function cures mainly: heat clearing away, pathogenic fire purging, removing heat from blood.Control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.
Rhizoma Belamcandae: Rhizoma Belamcandae, Chinese medicine name.For the dry rhizome of irides Rhizoma Belamcandae.Its bitter in the mouth, cold in nature.There is heat-clearing and toxic substances removing, expectorant, effect of sore-throat relieving, be usually used in pyretic toxicity phlegm-fire Tai and tie, laryngopharynx swelling and pain, accumulation and obstruction of sputum, cough and asthma.
Fructus Evodiae: another name Fructus Evodiae, tea is peppery, paint spicy, smelly spicy tree, Zuo Lichun deep and remote son, rice spicy etc.Function cures mainly:
Warming middle-JIAO, pain relieving, regulates the flow of vital energy, dampness, headache due to JUE YIN disorder, and the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, abdominal pain during menstruation, Diarrhoea, vascular hypertension, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.
Pericarpium Granati: sour and astringent, temperature, poisonous.Enter large intestine, lung, kidney channel.Function cures mainly: astringing intestine to stop diarrhea, hemostasis, anthelmintic.Control chronic diarrhea, chronic dysentery, have blood in stool, proctoptosis, spermatorrhea, metrorrhagia, leukorrhagia, abdominal pain due to worm stagnation, scabies.
Rhizoma Acori Graminei: root stock: bitter, pungent, temperature.Reduce phlegm, have one's ideas straightened out, spleen invigorating, dampness removing.For epilepsy, palpitate with fear forgetful, obnubilation, humidity hysteresis painful abdominal mass is swollen, dysentery, rheumatalgia, carbuncle scabies.
Galla Chinensis: have another name called hundred worm storehouses, Mass Galla chinesis et camelliae Fermentata, gall, meridian distribution of property and flavor: sour in the mouth is puckery, cold in nature.Return lung, large intestine, kidney channel.
Effect: astringe the lung; Hidroschesis; Astringing intestine to stop diarrhea; Controlling nocturnal emission with astringent drugs; Hemostasis; Removing toxic substances.Cure mainly: chronic cough of deficiency lung; Spontaneous sweating; Chronic dysentery chronic diarrhea; Proctoptosis; Seminal emission; Nebulousurine; Various hemorrhage; Carbuncle furuncle.
Herba Euphorbiae Humifusae: meridian distribution of property and flavor: pungent, flat; Lung, liver; Return stomach, large intestine, bladder.Can heat-clearing and toxic substances removing; Dampness removing jaundice eliminating; Promoting blood circulation and hemostasis.Main dysentery, have loose bowels, jaundice; Hemoptysis; Spit blood; Hematuria; Have blood in stool; Metrorrhagia; Agalactia; Treating swelling and pain by traumatic injury and pathopyretic ulcer etc.
Medulla Junci: function cures mainly: clearing heart fire, inducing diuresis for treating stranguria syndrome.Control gonorrhea, edema, dysuria, jaundice due to damp-heat, dysphoria and insomnia, the nocturnal fretfulness in infants, sore throat, wound.
Radix Gentianae: another name: Radix Gentianae, careless Radix Gentianae, Eumeces Chinensis gallbladder, meridian distribution of property and flavor: bitter in the mouth, cold in nature.Return liver, gallbladder meridian.Effect: heat clearing and damp drying; Eliminating pathogen in the liver is calmed the frightened.Jaundice due to damp-heat; Urine leaching pain; Swelling of the vulva pudendal pruritus; Damp-heat vaginal discharge; The feeling of fullness in the head headache of liver and gall excess-fire; Conjunctival congestion and swelling pain; Deaf ear swells; Hypochondriac pain bitter taste; Calentura convulsion with spasms.
The present invention's every mu of water surface use amount: 500 grams of pulverizes got by above Chinese medicine, adds 5 premium on currency and invades bubble 30 minutes, is then heated to boiling, micro-decoction 30 minutes of boiling, filtering extracting liquid.Three times repeatedly, merge three medicinal liquids.
The invention has the beneficial effects as follows: formula of the present invention is reasonable, preparation method is simple, and expense is low, has no side effect, and Therapeutic Method is convenient; Chinese herbal medicine has the features such as source is wide, toxicity is low, side effect is little, not easily develop immunity to drugs, and the application of Chinese herbal medicine in culture fishery in recent years gets more and more.The effective ingredient such as multiple alkaloid, volatile oil, organic acid in Chinese herbal medicine not only has bactericidal action but also have immunization, can improve the immunity of aquatic animal.
Detailed description of the invention
Embodiment 1, the present invention is made up of the Chinese medicine preparation of following weight portion:
Fructus Forsythiae 450 grams, Flos Lonicerae 450 grams, Fructus Gardeniae 550 grams, Rhizoma Belamcandae 450 grams, Fructus Evodiae 450 grams, Pericarpium Granati 550 grams, Rhizoma Acori Graminei 450 grams, Galla Chinensis 450 grams, Herba Euphorbiae Humifusae 450 grams, Medulla Junci 450 grams, Radix Gentianae 450 grams.
Usage of the present invention and consumption: every mu of water surface use amount: 500 grams of pulverizes got by above Chinese medicine, add 5 premium on currency and invade bubble 30 minutes, is then heated to boiling, micro-decoction 30 minutes of boiling, filtering extracting liquid.Three times repeatedly, merge three medicinal liquids.Get to decoct well-done medicinal liquid, thin up 50 times, evenly splash immediately to Misgurni anguillicaudati pond.Be used in conjunction 7 days, Misgurni anguillicaudati red head disease of Pseudobagrus can be treated, Be very effective.During prevention, consumption reduces by half.
Embodiment 2, the present invention is made up of the Chinese medicine preparation of following weight portion: Fructus Forsythiae 525 grams, Flos Lonicerae 425 grams, Fructus Gardeniae 425 grams, Rhizoma Belamcandae 525 grams, Fructus Evodiae 525 grams, Pericarpium Granati 525 grams, Rhizoma Acori Graminei 425 grams, Galla Chinensis 525 grams, Herba Euphorbiae Humifusae 525 grams, Medulla Junci 500 grams, Radix Gentianae 500 grams.The preparation method of the present embodiment and instructions of taking are with reference to embodiment 1.
Embodiment 3, the present invention is made up of the Chinese medicine preparation of following weight portion: Fructus Forsythiae 500 grams, Flos Lonicerae 525 grams, Fructus Gardeniae 500 grams, Rhizoma Belamcandae 500 grams, Fructus Evodiae 460 grams, Pericarpium Granati 500 grams, Rhizoma Acori Graminei 480 grams, Galla Chinensis 500 grams, Herba Euphorbiae Humifusae 500 grams, Medulla Junci 500 grams, Radix Gentianae 500 grams.The preparation method of the present embodiment and instructions of taking are with reference to embodiment 1.
Below by concrete performance, the present invention will be further described.
Certain loach breeding pond, area 1.2 mu, the depth of water 0.6 meter, 1200 kilograms, the pool was deposited in pond, through visual inspection August
After microscopy, be defined as Misgurni anguillicaudati red head disease of Pseudobagrus, 500 grams of pulverizes respectively got by above Chinese medicine, add 5 premium on currency and invade bubble 30 minutes, are then heated to boiling, micro-decoction 30 minutes of boiling, filtering extracting liquid.Three times repeatedly, merge three medicinal liquids.Get to decoct well-done medicinal liquid, thin up 50 times, evenly splash immediately to Misgurni anguillicaudati pond.Be used in conjunction 7 days, this sick curative effect is obvious.
Especially by experiment pool with contrast pond contrast distinguish as follows:
The treatment by Chinese herbs of No. 1 pond above-described embodiment, No. 2 general antibacterial drug therapies in pond, comparing result is as follows:

Claims (3)

1. treat a Chinese medicine for Misgurni anguillicaudati red head disease of Pseudobagrus, it is characterized in that being made up of the Chinese medicine component of following weight portion: Fructus Forsythiae 450-550 gram, Flos Lonicerae 450-550 gram, Fructus Gardeniae 450-550 gram, Rhizoma Belamcandae 450-550 gram, Fructus Evodiae 450-550 gram, Pericarpium Granati 450-550 gram, Rhizoma Acori Graminei 450-550 gram, Galla Chinensis 450-550 gram, Herba Euphorbiae Humifusae 450-550 gram, Medulla Junci 450-550 gram, Radix Gentianae 450-550 gram.
2. the Chinese medicine for the treatment of Misgurni anguillicaudati red head disease of Pseudobagrus according to claim 1, is characterized in that being made up of the Chinese medicine component of following weight portion: Fructus Forsythiae 425-525 gram, Flos Lonicerae 425-525 gram, Fructus Gardeniae 425-525 gram, Rhizoma Belamcandae 425-525 gram, Fructus Evodiae 425-525 gram, Pericarpium Granati 425-525 gram, Rhizoma Acori Graminei 425-525 gram, Galla Chinensis 425-525 gram, Herba Euphorbiae Humifusae 425-525 gram, Medulla Junci 425-525 gram, Radix Gentianae 425-525 gram.
3. the Chinese medicine for the treatment of Misgurni anguillicaudati red head disease of Pseudobagrus according to claim 1, is characterized in that being made up of the Chinese medicine of following weight portion: Fructus Forsythiae 500 grams, Flos Lonicerae 500 grams, Fructus Gardeniae 500 grams, Rhizoma Belamcandae 500 grams, Fructus Evodiae 500 grams, Pericarpium Granati 500 grams, Rhizoma Acori Graminei 500 grams, Galla Chinensis 500 grams, Herba Euphorbiae Humifusae 500 grams, Medulla Junci 500 grams, Radix Gentianae 500 grams.
CN201410700848.5A 2014-11-28 2014-11-28 TCM (traditional Chinese medicine) preparation for treatment of red-head diseases of loaches Pending CN104474175A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108783115A (en) * 2018-07-12 2018-11-13 漳州傲农牧业科技有限公司 A kind of immunopotentiator and the preparation method and application thereof preventing red head disease of Pseudobagrus fulvidraco

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108783115A (en) * 2018-07-12 2018-11-13 漳州傲农牧业科技有限公司 A kind of immunopotentiator and the preparation method and application thereof preventing red head disease of Pseudobagrus fulvidraco

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Application publication date: 20150401