CN104473169B - A kind of health product containing fish glue and preparation method thereof - Google Patents
A kind of health product containing fish glue and preparation method thereof Download PDFInfo
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- CN104473169B CN104473169B CN201410829738.9A CN201410829738A CN104473169B CN 104473169 B CN104473169 B CN 104473169B CN 201410829738 A CN201410829738 A CN 201410829738A CN 104473169 B CN104473169 B CN 104473169B
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention provides a kind of health product containing fish glue and preparation method thereof.Method is: takes Radix Ginseng, Ganoderma, adds purified water respectively, by heating, boils extraction, filters, with macromolecule reverse osmosis membrane carry out separating, eluting, concentrating under reduced pressure, obtain Radix Ginseng and Ganoderma extracting solution；After adding 2 times of purified water in fish glue, change glue 30min at 70 80 DEG C, add purified water afterwards, crack protein 30min at 90 100 DEG C, afterwards crack protein 30min at 100 110 DEG C, obtain cracking extracting solution and residue；By residue crack protein 30min at 90 100 DEG C, crack protein 30min at 100 110 DEG C afterwards；Merge twice lysate, then concentrating under reduced pressure, concentrated solution is centrifuged, filter, obtain fish glue extracting solution；Above-mentioned each solution and crystal sugar solution are mixed.Active component in medical material can fully be extracted by the present invention, and beneficially human body quickly absorbs, and improves nutrition absorption rate.
Description
Technical field
The present invention relates to field of health care products, in particular to a kind of health product containing fish glue
And preparation method thereof.
Background technology
The dry products of fish glue i.e. Air Bladder pseudosciaenae seu Acipenser (assisted respiartion organ), rich colloid, therefore named fish glue,
Also referred to as fish maw, Air Bladder pseudosciaenae seu Acipenser.Fish glue and Nidus collocaliae, Fin Mustetus manazo are equally celebrated for their achievements, are one of " eight delicacies ", have " sea
Foreigner join " reputation.It is mainly composed of senior collagen protein, multivitamin and calcium, zinc,
The various trace elements such as ferrum, selenium.Its protein content is up to 84.2%, and fat is only 0.2%,
It is preferable high protein and low fat food.Be human body supplement, the raw material of synthetic protein, and
It is prone to absorb and utilize.
Fish glue can strengthen the digestive and absorptive functions of gastrointestinal, improves appetite, is conducive to preventing and treating appetite
The diseases such as depressed, dyspepsia, constipation；Toughness and the elastic force of muscular tissue can be strengthened, increase
Strong muscle power, allaying tiredness；Cranial nerve function, enhancing development can be strengthened, improve thinking
And intelligence, maintain body of gland normal secretions；Bradykinesia, dysplasia of children, product can be prevented and treated
Woman's galactopoiesis is not enough, old forgetful insomnia etc..Owing to fish glue contains a large amount of glue juice, have again
Invigorate blood circulation, enrich blood, stop blooding, effects such as damp eliminating of keeping out the cold, so immunity can be improved, for
Have a delicate constitution, Kidney-Yin loss, the personage of psychentonia, more particularly suitable as nourishing.Except this
In addition, fish glue or the optimum selection of women replenishing collagen.Albumen in human body skin
Matter has 70% to be collagen protein, and the network structure formed supports skin, makes skin see
Come smooth full, softness high resilience again.With advancing age, the glue in skin histology
The speed of former protein loss has exceeded the speed generated gradually, and then skin follows the string thinning
Aging, lax, wrinkle, the phenomenon such as dry and astringent occur, so replenishing collagen in good time, can
Skin is made to renew one's youth vigor.
At present, the health product containing fish glue are varied, mainly have two classes: one is only fish
The health product of glue single component, a kind of combined health being fish glue and mixing with other medical material
Product.Wherein, combined health care products is nutritious the most more favourable with it.
The existing combined health care products containing fish glue mainly uses following two method to make: one,
Powder will be obtained after mixing after all the components pulverizing；Two, all the components is dissolved in a certain molten
Agent is formed oral liquid.Both approaches all there is problems in that in fish glue and other medical material
Effective ingredient the most fully discharge, cause taking rear nutrition absorption rate low.
In view of this, the special proposition present invention.
Summary of the invention
The first object of the present invention is to provide the preparation method of a kind of health product containing fish glue,
Active component in fish glue and Radix Ginseng, Ganoderma can fully be extracted by described preparation method,
It is beneficial to human body quickly absorb, improves nutrition absorption rate.
The second object of the present invention is to provide a kind of described health product containing fish glue, this guarantor
Strong product have the purposes of enhancing human body immunity function and alleviating physical fatigue, and which are added
Crystal sugar, sweet taste improves, more favourable.
In order to realize the above-mentioned purpose of the present invention, spy by the following technical solutions:
The preparation method of a kind of health product containing fish glue, comprises the steps of:
Step A: by weight, takes 1500-2500 part Radix Ginseng, adds the purified water of 12 times amount,
By heating, boil extraction 2 times, refilter, merging filtrate, then use macromolecule reverse osmosis
Film carries out separating, eluting, then to be evaporated to relative density be 1.05-1.10, obtains Radix Ginseng
Extracting solution；
Step B: take 2500-3500 part Ganoderma, is carried out and the people in described step A it
Join identical process, obtain Ganoderma extracting solution；
Step C: take 2500-3500 part fish glue, after adding the purified water of 2 times amount, at 70-80 DEG C
Change glue 30min, add to the purified water of 6 times amount afterwards, crack protein at 90-100 DEG C
30min, crack protein 30min at 100-110 DEG C, is once cracked extracting solution afterwards
And residue；
Step D: by described residue crack protein 30min at 90-100 DEG C, exist afterwards
Crack protein 30min at 100-110 DEG C, obtains second pyrolysis extracting solution；
Step E: once crack extracting solution and described second pyrolysis extracting solution described in merging, then
Concentrating under reduced pressure, obtains concentrated solution；
Step F: be centrifuged under 12000rpm by described concentrated solution, uses ceramic membrane filter,
The molecular cut off effective protein ingredient of little molecule less than 6000, obtains fish glue extracting solution；
Step G: take 1500-2500 part crystal sugar, be added thereto to the water of 4 times amount, make ice
Sugar dissolves, and obtains crystal sugar solution；
Step H: described Radix Ginseng extractive solution, described Ganoderma extracting solution, described fish glue are extracted
Liquid and the mixing of described crystal sugar solution, filtration, obtain product.
In above-mentioned preparation method, by heating, filtration and macromolecule reverse osmosis membrane separation, wash
Active component in Radix Ginseng and Ganoderma fully is extracted out by de-mode；Also by cracking
Active component in fish glue fully is extracted out by the mode of albumen, thus obtains a kind of battalion
Support the health product that absorbance is high.Wherein, when preparing fish glue extracting solution, first at 90-100 DEG C
Lower crack protein, cracking fish glue at 100-110 DEG C twice could be fully by effective ingredient again
Extract, and protein ingredient is cracked into the absorbable albumen of human body.
Further, in described step A and B, with macromolecule reverse osmosis membrane carry out separating,
Afford the nutritional labeling that molecular weight is less than 4000.
Effective ingredient in the following Radix Ginseng of this molecular weight and Ganoderma is all collected.
Further, in described step A and B, the time of each heating extraction is 1.5h.
Being found by research, at this time point, extraction ratio is to peak.
Further, in described step A and B, the most also include: with 200
Purpose sieves filters.Invalid components in solution can be crossed by the filtration of this particle diameter and filter
Go.
Further, in described step G, also include after crystal sugar melts: use 120 purposes
Sieves filters.Contaminant filter in crystal sugar can be removed by the filtration of this particle diameter.
Further, in described step H, it is filtered into: filter with the sieves of 180 mesh.
Invalid components in solution can be filtered to remove by the filtration of this particle diameter.
Further, described step A takes Radix Ginseng 2000 parts；Described step B takes spirit
Sesame 3000 parts；Described step C takes 3000 parts of fish glue；Described step H takes crystal sugar
2000 parts.
Further, in described step A and B, the condition of described concentrating under reduced pressure is:
0.07MPa、75-85℃.Use this condition thickening efficiency high, and can ensure that the most molten
The effective ingredient gone out is not destroyed.
Further, in described step G, the method making crystal sugar dissolve is: heating.To add
Speed crystal sugar fusing.
A kind of health product containing fish glue, it uses arbitrary preparation method above to prepare.
Compared with prior art, the invention have the benefit that
(1) effective ingredient in fish glue, Radix Ginseng and Ganoderma fully it is extracted.
(2) nutrition absorption rate is high.
(3) health product is in good taste.
(4) the enhancing human body immunity function of health product and the effect of alleviating physical fatigue are brighter
Aobvious.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but this
Skilled person is it will be appreciated that the following example is merely to illustrate the present invention, and should not regard
For limiting the scope of the present invention.Unreceipted actual conditions person in embodiment, according to normal condition
Or the condition of manufacturer's suggestion is carried out.Agents useful for same or instrument unreceipted production firm person, all
For the conventional products that can be obtained by commercially available purchase.
Embodiment 1
A kind of health product containing fish glue, consist of the following composition: Radix Ginseng 2000 parts, Ganoderma
3000 parts, 3000 parts of fish glue, 2000 parts of crystal sugar.
Embodiment 2
A kind of health product containing fish glue, consist of the following composition: Radix Ginseng 1500 parts, Ganoderma
2500 parts, 2500 parts of fish glue, 1500 parts of crystal sugar.
Embodiment 3
A kind of health product containing fish glue, consist of the following composition: Radix Ginseng 1600 parts, Ganoderma
2600 parts, 2600 parts of fish glue, 1600 parts of crystal sugar.
Embodiment 4
A kind of health product containing fish glue, consist of the following composition: Radix Ginseng 1700 parts, Ganoderma
2700 parts, 2700 parts of fish glue, 1700 parts of crystal sugar.
Embodiment 5
A kind of health product containing fish glue, consist of the following composition: Radix Ginseng 1800 parts, Ganoderma
2800 parts, 2800 parts of fish glue, 1800 parts of crystal sugar.
Embodiment 6
A kind of health product containing fish glue, consist of the following composition: Radix Ginseng 1900 parts, Ganoderma
2900 parts, 2900 parts of fish glue, 1900 parts of crystal sugar.
Embodiment 7
A kind of health product containing fish glue, consist of the following composition: Radix Ginseng 2100 parts, Ganoderma
3100 parts, 3100 parts of fish glue, 2100 parts of crystal sugar.
Embodiment 8
A kind of health product containing fish glue, consist of the following composition: Radix Ginseng 2200 parts, Ganoderma
3200 parts, 3200 parts of fish glue, 2200 parts of crystal sugar.
Embodiment 9
A kind of health product containing fish glue, consist of the following composition: Radix Ginseng 2300 parts, Ganoderma
3300 parts, 3300 parts of fish glue, 2300 parts of crystal sugar.
Embodiment 10
A kind of health product containing fish glue, consist of the following composition: Radix Ginseng 2400 parts, Ganoderma
3400 parts, 3400 parts of fish glue, 2400 parts of crystal sugar.
Embodiment 11
A kind of health product containing fish glue, consist of the following composition: Radix Ginseng 2500 parts, Ganoderma
3500 parts, 3500 parts of fish glue, 2500 parts of crystal sugar.
Above example 1-11 can use the method for embodiment 12 or 13 to prepare.
Embodiment 12
The preparation method of a kind of health product containing fish glue, comprises the steps of:
Step A: take Radix Ginseng, adds the purified water of 12 times amount, by heating extraction 2 times, then
Filter, merging filtrate, then with macromolecule reverse osmosis membrane carry out separating, eluting, then it is dense to reduce pressure
Being reduced to relative density is 1.05-1.10, obtains Radix Ginseng extractive solution；
Step B: take Ganoderma, carries out the process identical with the Radix Ginseng in described step A to it,
Obtain Ganoderma extracting solution；
Step C: take fish glue, after adding the purified water of 2 times amount, changes glue 30min at 70-80 DEG C,
Add to the purified water (referring on the basis of the water yield added for the first time) of 6 times amount afterwards,
Crack protein 30min at 90-100 DEG C, afterwards crack protein 30min at 100-110 DEG C,
Once cracked extracting solution and residue；
Step D: by described residue crack protein 30min at 90-100 DEG C, exist afterwards
Crack protein 30min at 100-110 DEG C, obtains second pyrolysis extracting solution；
Step E: once crack extracting solution and described second pyrolysis extracting solution described in merging, then
Concentrating under reduced pressure, obtains concentrated solution；
Step F: be centrifuged under 12000rpm by described concentrated solution, uses ceramic membrane filter,
The molecular cut off effective protein ingredient of little molecule less than 6000, obtains fish glue extracting solution；
Step G: take crystal sugar, is added thereto to the water of 4 times amount, makes crystal sugar dissolve, obtains ice
Sugar juice；
Step H: described Radix Ginseng extractive solution, described Ganoderma extracting solution, described fish glue are extracted
Liquid and the mixing of described crystal sugar solution, filtration, obtain product.
Embodiment 13
Take Radix Ginseng slice, Ganoderma tablet, after correct amount, add the purified water of 12 times amount, heating,
Boil, extract 2 times, 1.5h/ time, plate-and-frame filtration (200 mesh), merging filtrate, use high score
Sub-reverse osmosis membrane carries out separating, eluting, it is thus achieved that less than the ganoderan below 4000 dalton
With effective active compositions such as ginsenosides, concentrating under reduced pressure (0.07MPa, 75-85 DEG C) is to phase
To density 1.05-1.10 (60 DEG C), obtain concentrated solution, standby.
The preparation of described fish glue extracting solution: take fish glue, after correct amount, adds 2 times amount
Purified water, at 70-80 DEG C of carrying out glue 30min, adds to the purified water of 6 times amount afterwards, uses
Secondary cycle mode cracks 2 times, crack protein 30min, electrical heating at i.e. 90-100 DEG C
100-110 DEG C of crack protein 30min, 90-100 DEG C of cracking 30min, and electrical heating
100-110 DEG C of cracking 30min.Merge cracking extracting solution, concentrating under reduced pressure.Concentrated solution exists
Being centrifuged under 12000rpm, use ceramic membrane filter, molecular cut off is less than little point of 6000
Son effectively protein ingredient, stored refrigerated, prepare the fish glue extracting solution without precipitation, standby.
By ginseng and lucid ganoderma extracting solution, fish glue extracting solution, three kinds of solution of crystal sugar solution, mix
Close, stir, by amount of calculation addition purified water to the most enough, place, filter (180 mesh),
Liquid must be prepared, through canned, sterilizing, thus obtaining the product oral liquid.
Experimental example 1
Safety according to " health food inspection and assessment technique specification " (version in 2003)
The program evaluated with functional trial and method, the oral liquid mainly present invention prepared
Significant composition, hygiology, stability, toxicology, function assessment (enhancing immunity are carried out
Power function, function of physical fatigue alleviation).Experimental technique is as follows, and experimental result refers to table.
Note: the oral liquid of the present invention uses formula and the method system of embodiment 13 of embodiment 1
?.
1, toxicological experiment
1.1 acute oral toxicity tests:
Laboratory animal: Kunming kind mice female, male (SPF level).
Experimental technique: use maximum tolerated dose method, Kunming mouse is weighed, and at random
Packet, gastric infusion, observe and record animal state.
1.2 three genetic toxicity tests
1.2.1Ames test:
Experimental strain: Salmonella typhimurium histidine deficient
TA97\TA98\TA100\TA102。
Experimental technique: use the rat liver microsomes enzyme (S-9) of Polychlorinated biphenyls PCB induction to make
For In vitro metabolism active system.It is divided into 5 dosage, if certainly beaming back change, solvent control and sun
Property mutagens comparison.
1.2.2 mice bone marrow micronucleus:
Laboratory animal: use Kunming mouse.
Experimental technique: random point 5 groups, male and female half and half.With cyclophosphamide as positive control,
Distilled water is negative control, if senior middle school's low dose group.
1.2.3 mouse inbred strain:
Laboratory animal: male mice in kunming；
Experimental technique and step: be randomly divided into 5 groups, with cyclophosphamide as positive control, steam
Distilled water is negative control, if senior middle school's low dose group.
1.330 it feeding trial
Laboratory animal: SD rat, male and female half and half.
Experimental technique and step: matched group, senior middle school's low dose group, 6.25 that the present invention is prepared
Times oral liquid gavage.
Overall toxicological experiment result shows, 6.25 times of these concentrated solutions maximum to experimental animal
Dosis tolerata is more than 21.07g/kg bw, belongs to nontoxic level.Salmonella reversion test, mouse bone marrow cells are addicted to polychromatophilia
Micronucleus in erythrocytes test, mouse inbred strain result are feminine gender.30 days feeding trials
Result shows rat is had no obvious toxic-side effects.
Above-mentioned experimental result such as following table 1-6
Table 1 sample acute toxicity test in mice result
Table 2 sample Salmonella reversion test result (for the second time)
Table 3 sample Salmonella reversion test result (for the second time) continues
The impact on Micronuclei In The Mouse Bone Marrow incidence rate of table 4 sample
Note: * compares with negative control group, P < 0.01.
The impact on Sperm Abnormalities of Mice of table 5 sample
Note: * compares with negative control group, P < 0.01.
30 days feeding trial biochemical investigation in latter stage results of table 6 sample
2 function assessment tests
2.1 enhancing immunity functions
Per os gavage gives this concentrated solution 30 days of the high, normal, basic dosage of mice, with matched group ratio
Relatively, middle and high dosage group can significantly improve mice delayed allergy ability, antibody tormation
Cell number, NK cytoactive, high dose energy consummate raising mice carbonic clearance phagocytic index,
Half hemolysis value (P < 0.05), each dosage to Mouse Weight growth, thymus/body weight ratio,
Spleen/body weight ratio, lymphocyte transformation ability and the ability of macrophage phagocytic chicken red blood cell
All do not make significant difference (P > 0.05).Result shows, the oral liquid of the present invention has enhancing immunity
Power function.
2.2 function of physical fatigue alleviation zooperies
Per os gives the oral liquid 30 days of the high, normal, basic dosage of mice, and high dose can be obviously prolonged little
Serum after the heavy burden playtime of Mus, increase Mouse Liver glycogen storage level, reduction mouse movement
Urea level, has significance (P < 0.05) with matched group comparing difference.Each dosage is to Mouse Blood
Lactic acid area under curve has no and significantly affects (P > 0.05).Result shows, the present invention's is oral
Liquid has function of physical fatigue alleviation.
In summary, compared with prior art, a kind of group containing fish glue that the present invention provides
Having the beneficial effect that of compound:
1) there is enhancing immunity through Chinese medicine and modern pharmacology research theoretical proof
Be primary raw material with Radix Ginseng, the Ganoderma of alleviating physical fatigue, can vigorate qi and replenish the blood, the kidney invigorating lung benefiting,
Integrally-regulated, strengthening vital QI to eliminate pathogenic factors, reaches the health-care effect of enhancing immunity and alleviating physical fatigue.
And persistent, raw material sources are extensive, the material benefit of reliable in quality, price.
2) the fish glue raw material used by, has the merit of the liver and the kidney tonifying, nourishing blood and hemoslasis, dissipating blood stasis for subsidence of swelling
Effect, containing abundant nutritional labeling, Air Bladder pseudosciaenae seu Acipenser has colloid, is enriched in high protein, low fat
With the important aquatic food resource of mineral, have the reputation of " ocean Radix Ginseng ", there is nourishing and make
With and medical value.
3) raw materials used being safe healthy food material, adjuvant used is few, prohibits without compatibility
Avoiding, in formula, the consumption of raw material is all in the range of safety using amount, and production technology meets food and defends
Raw related request, therefore this product edible safety, without any side effects, can be eaten for a long time.
4) selecting Radix Ginseng, Ganoderma is conventional Chinese medicine, in ginsenoside in Radix Ginseng, Ganoderma
Polysaccharide components etc. all have good water solublity.Fish glue is conventional nutraceutical, among the people mostly
Take to stew.Therefore, according to being conducive to keeping and developing the spy of Chinese medicine traditional decoction
Point and advantage, this product selects oral liquid formulation, has and is easy to take, absorb soon, Yi Jigong
Skill is simple, sterilization preparation easily reaches sanitary standard, steady quality, with low cost etc. excellent
Point, it is adaptable to vast need crowd.
5) use unique extraction conditions, both improve the extraction ratio of effective ingredient, and improved again
The molecular weight of nutritional labeling so that it is be more easy to absorb.
Although illustrate and describing the present invention with specific embodiment, but it will be appreciated that
May be made that without departing from the spirit and scope of the present invention many other change and
Amendment.It is, therefore, intended that include in the following claims belonging in the scope of the invention
All such changes and modifications.
Claims (10)
1. the preparation method of the health product containing fish glue, it is characterised in that by following steps
Composition:
Step A: by weight, takes 1500-2500 part Radix Ginseng, adds the purified water of 12 times amount,
By heating extraction 2 times, refilter, merging filtrate, then carry out point with macromolecule reverse osmosis membrane
From, eluting, then to be evaporated to relative density be 1.05-1.10, obtains Radix Ginseng extractive solution；
Step B: take 2500-3500 part Ganoderma, add the purified water of 12 times amount, by heating
Extract 2 times, refilter, merging filtrate, then with macromolecule reverse osmosis membrane carry out separating, eluting,
Being evaporated to relative density again is 1.05-1.10, obtains Ganoderma extracting solution；
Step C: take 2500-3500 part fish glue, after adding the purified water of 2 times amount, at 70-80 DEG C
Change glue 30min, add to the purified water of 6 times amount afterwards, crack protein at 90-100 DEG C
30min, afterwards crack protein 30min at 100-110 DEG C, once cracked extracting solution and
Residue；
Step D: by described residue crack protein 30min at 90-100 DEG C, exist afterwards
Crack protein 30min at 100-110 DEG C, obtains second pyrolysis extracting solution；
Step E: once crack extracting solution and described second pyrolysis extracting solution described in merging, then subtract
Pressure concentrates, and obtains concentrated solution；
Step F: be centrifuged under 12000rpm by described concentrated solution, uses ceramic membrane filter,
The molecular cut off effective protein ingredient of little molecule less than 6000, obtains fish glue extracting solution；
Step G: take 1500-2500 part crystal sugar, be added thereto to the water of 4 times amount, make crystal sugar
Dissolve, obtain crystal sugar solution；
Step H: by described Radix Ginseng extractive solution, described Ganoderma extracting solution, described fish glue extracting solution
With the mixing of described crystal sugar solution, filtration, obtain product.
The preparation method of the health product containing fish glue the most according to claim 1, its feature
It is, in described step A and B, carries out separating with macromolecule reverse osmosis membrane, afford point
Son amount is the nutritional labeling of less than 4000.
The preparation method of the health product containing fish glue the most according to claim 1, its feature
Being, in described step A and B, the time of each heating extraction is 1.5h.
The preparation method of the health product containing fish glue the most according to claim 1, its feature
It is, in described step H, is filtered into: filter with the sieves of 180 mesh.
The preparation method of the health product containing fish glue the most according to claim 1, its feature
It is, described step A takes Radix Ginseng 2000 parts；Described step B takes Ganoderma 3000 parts；
Described step C takes 3000 parts of fish glue；Described step G takes 2000 parts of crystal sugar.
The preparation method of the health product containing fish glue the most according to claim 1, its feature
Being, in described step A and B, the condition of described concentrating under reduced pressure is: 0.07MPa, 75-85 DEG C.
The preparation method of the health product containing fish glue the most according to claim 1, its feature
Being, in described step G, the method making crystal sugar dissolve is: heating.
8. the preparation method of the health product containing fish glue, it is characterised in that by following steps
Composition:
Step A: by weight, takes 1500-2500 part Radix Ginseng, adds the purified water of 12 times amount,
By heating extraction 2 times, refilter, merging filtrate, then carry out point with macromolecule reverse osmosis membrane
From, eluting, then to be evaporated to relative density be 1.05-1.10, with the sieves of 200 mesh
Filter, obtain Radix Ginseng extractive solution；
Step B: take 2500-3500 part Ganoderma, add the purified water of 12 times amount, by heating
Extract 2 times, refilter, merging filtrate, then with macromolecule reverse osmosis membrane carry out separating, eluting,
Being evaporated to relative density again is 1.05-1.10, filters with the sieves of 200 mesh, obtains
Ganoderma extracting solution；
Step C: take 2500-3500 part fish glue, after adding the purified water of 2 times amount, at 70-80 DEG C
Change glue 30min, add to the purified water of 6 times amount afterwards, crack protein at 90-100 DEG C
30min, afterwards crack protein 30min at 100-110 DEG C, once cracked extracting solution and
Residue；
Step D: by described residue crack protein 30min at 90-100 DEG C, exist afterwards
Crack protein 30min at 100-110 DEG C, obtains second pyrolysis extracting solution；
Step E: once crack extracting solution and described second pyrolysis extracting solution described in merging, then subtract
Pressure concentrates, and obtains concentrated solution；
Step F: be centrifuged under 12000rpm by described concentrated solution, uses ceramic membrane filter,
The molecular cut off effective protein ingredient of little molecule less than 6000, obtains fish glue extracting solution；
Step G: take 1500-2500 part crystal sugar, be added thereto to the water of 4 times amount, make crystal sugar
Dissolve, obtain crystal sugar solution；
Step H: by described Radix Ginseng extractive solution, described Ganoderma extracting solution, described fish glue extracting solution
With the mixing of described crystal sugar solution, filtration, obtain product.
9. the preparation method of the health product containing fish glue, it is characterised in that by following steps
Composition:
Step A: by weight, takes 1500-2500 part Radix Ginseng, adds the purified water of 12 times amount,
By heating extraction 2 times, refilter, merging filtrate, then carry out point with macromolecule reverse osmosis membrane
From, eluting, then to be evaporated to relative density be 1.05-1.10, obtains Radix Ginseng extractive solution；
Step B: take 2500-3500 part Ganoderma, add the purified water of 12 times amount, by heating
Extract 2 times, refilter, merging filtrate, then with macromolecule reverse osmosis membrane carry out separating, eluting,
Being evaporated to relative density again is 1.05-1.10, obtains Ganoderma extracting solution；
Step C: take 2500-3500 part fish glue, after adding the purified water of 2 times amount, at 70-80 DEG C
Change glue 30min, add to the purified water of 6 times amount afterwards, crack protein at 90-100 DEG C
30min, afterwards crack protein 30min at 100-110 DEG C, once cracked extracting solution and
Residue；
Step D: by described residue crack protein 30min at 90-100 DEG C, exist afterwards
Crack protein 30min at 100-110 DEG C, obtains second pyrolysis extracting solution；
Step E: once crack extracting solution and described second pyrolysis extracting solution described in merging, then subtract
Pressure concentrates, and obtains concentrated solution；
Step F: be centrifuged under 12000rpm by described concentrated solution, uses ceramic membrane filter,
The molecular cut off effective protein ingredient of little molecule less than 6000, obtains fish glue extracting solution；
Step G: take 1500-2500 part crystal sugar, be added thereto to the water of 4 times amount, make crystal sugar
Dissolve, filter with the sieves of 120 mesh, obtain crystal sugar solution；
Step H: by described Radix Ginseng extractive solution, described Ganoderma extracting solution, described fish glue extracting solution
With the mixing of described crystal sugar solution, filtration, obtain product.
10. the health product containing fish glue, it is characterised in that use claim 1-9 arbitrary
The preparation method of the health product containing fish glue described in Xiang is made.
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| CN109045101A (en) * | 2018-09-26 | 2018-12-21 | 北京维特百草健康科技有限公司 | Chinese medicine composition and its application containing Chinese medical extract |
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| CN107397208B (en) * | 2016-07-20 | 2021-05-07 | 吴登成 | Functional food containing fish glue as main component and its use |
| CN107259561A (en) * | 2017-05-12 | 2017-10-20 | 广东利泰大健康产业股份有限公司 | Flower of Panax ginseng glue drink and preparation method thereof |
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| CN1557207A (en) * | 2004-01-21 | 2004-12-29 | 雨田集团有限公司 | Swimming bladder glue product and its making process |
| CN1919077A (en) * | 2006-09-15 | 2007-02-28 | 孙庆海 | Fish maw glue powder and its processing method |
| CN101647562A (en) * | 2009-07-23 | 2010-02-17 | 杭州六易科技有限公司 | Preparation method of lady beauty and healthcare beverage |
| CN101999582A (en) * | 2010-12-25 | 2011-04-06 | 河南科技大学 | Yam-swimming bladder collagen chewable tabs and preparation method thereof |
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|---|---|---|---|---|
| CN1557207A (en) * | 2004-01-21 | 2004-12-29 | 雨田集团有限公司 | Swimming bladder glue product and its making process |
| CN1919077A (en) * | 2006-09-15 | 2007-02-28 | 孙庆海 | Fish maw glue powder and its processing method |
| CN101647562A (en) * | 2009-07-23 | 2010-02-17 | 杭州六易科技有限公司 | Preparation method of lady beauty and healthcare beverage |
| CN101999582A (en) * | 2010-12-25 | 2011-04-06 | 河南科技大学 | Yam-swimming bladder collagen chewable tabs and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109045101A (en) * | 2018-09-26 | 2018-12-21 | 北京维特百草健康科技有限公司 | Chinese medicine composition and its application containing Chinese medical extract |
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