CN103610112A - Immunity-enhancing sea cucumber oral liquid and application method thereof - Google Patents
Immunity-enhancing sea cucumber oral liquid and application method thereof Download PDFInfo
- Publication number
- CN103610112A CN103610112A CN201310490940.9A CN201310490940A CN103610112A CN 103610112 A CN103610112 A CN 103610112A CN 201310490940 A CN201310490940 A CN 201310490940A CN 103610112 A CN103610112 A CN 103610112A
- Authority
- CN
- China
- Prior art keywords
- sea cucumber
- oral liquid
- immunity
- parts
- enhancing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000251511 Holothuroidea Species 0.000 title claims abstract description 131
- 239000007788 liquid Substances 0.000 title claims abstract description 64
- 238000000034 method Methods 0.000 title claims abstract description 21
- 230000036039 immunity Effects 0.000 claims abstract description 27
- 244000241838 Lycium barbarum Species 0.000 claims abstract description 20
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 20
- 210000000582 semen Anatomy 0.000 claims abstract description 20
- 241000282458 Ursus sp. Species 0.000 claims abstract description 9
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 8
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 4
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 4
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 4
- 239000011718 vitamin C Substances 0.000 claims abstract description 4
- 240000001398 Typha domingensis Species 0.000 claims abstract 2
- 241000512259 Ascophyllum nodosum Species 0.000 claims description 19
- 244000153955 Reynoutria sachalinensis Species 0.000 claims description 19
- 235000003202 Reynoutria sachalinensis Nutrition 0.000 claims description 19
- 240000007164 Salvia officinalis Species 0.000 claims description 16
- 235000005412 red sage Nutrition 0.000 claims description 16
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 8
- 239000011575 calcium Substances 0.000 claims description 8
- 229910052791 calcium Inorganic materials 0.000 claims description 8
- 210000004369 blood Anatomy 0.000 abstract description 26
- 239000008280 blood Substances 0.000 abstract description 26
- 230000002708 enhancing effect Effects 0.000 abstract description 6
- 230000036772 blood pressure Effects 0.000 abstract description 4
- 244000118350 Andrographis paniculata Species 0.000 abstract 1
- 235000004347 Perilla Nutrition 0.000 abstract 1
- 244000124853 Perilla frutescens Species 0.000 abstract 1
- 244000292697 Polygonum aviculare Species 0.000 abstract 1
- 235000006386 Polygonum aviculare Nutrition 0.000 abstract 1
- 241000015177 Saccharina japonica Species 0.000 abstract 1
- 241000304195 Salvia miltiorrhiza Species 0.000 abstract 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 abstract 1
- 241000222355 Trametes versicolor Species 0.000 abstract 1
- 229960004494 calcium gluconate Drugs 0.000 abstract 1
- 235000013927 calcium gluconate Nutrition 0.000 abstract 1
- 239000004227 calcium gluconate Substances 0.000 abstract 1
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 35
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 30
- 239000004365 Protease Substances 0.000 description 30
- 239000000706 filtrate Substances 0.000 description 30
- 230000001954 sterilising effect Effects 0.000 description 30
- 239000000284 extract Substances 0.000 description 28
- 239000003814 drug Substances 0.000 description 22
- 108091005804 Peptidases Proteins 0.000 description 20
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 20
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 20
- 239000000843 powder Substances 0.000 description 20
- 235000019419 proteases Nutrition 0.000 description 20
- 241000233948 Typha Species 0.000 description 18
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 17
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 16
- 239000000654 additive Substances 0.000 description 15
- 150000001875 compounds Chemical class 0.000 description 15
- 230000002255 enzymatic effect Effects 0.000 description 15
- 238000011049 filling Methods 0.000 description 15
- 238000001914 filtration Methods 0.000 description 15
- 230000000694 effects Effects 0.000 description 11
- 235000013336 milk Nutrition 0.000 description 11
- 239000008267 milk Substances 0.000 description 11
- 210000004080 milk Anatomy 0.000 description 11
- 238000012545 processing Methods 0.000 description 11
- 108010004032 Bromelains Proteins 0.000 description 10
- 102000004190 Enzymes Human genes 0.000 description 10
- 108090000790 Enzymes Proteins 0.000 description 10
- 235000019835 bromelain Nutrition 0.000 description 10
- 238000004140 cleaning Methods 0.000 description 10
- 238000004108 freeze drying Methods 0.000 description 10
- 238000000227 grinding Methods 0.000 description 10
- 238000010438 heat treatment Methods 0.000 description 10
- 239000012535 impurity Substances 0.000 description 10
- 210000003734 kidney Anatomy 0.000 description 10
- 210000004027 cell Anatomy 0.000 description 9
- 239000000203 mixture Substances 0.000 description 8
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 8
- 235000012000 cholesterol Nutrition 0.000 description 7
- 235000013305 food Nutrition 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- 230000008569 process Effects 0.000 description 7
- 208000001953 Hypotension Diseases 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 208000021822 hypotensive Diseases 0.000 description 6
- 230000001077 hypotensive effect Effects 0.000 description 6
- 235000012054 meals Nutrition 0.000 description 6
- 241000965254 Apostichopus japonicus Species 0.000 description 5
- 241000196324 Embryophyta Species 0.000 description 5
- 210000001015 abdomen Anatomy 0.000 description 5
- 239000003963 antioxidant agent Substances 0.000 description 5
- 230000003078 antioxidant effect Effects 0.000 description 5
- 235000006708 antioxidants Nutrition 0.000 description 5
- 239000000022 bacteriostatic agent Substances 0.000 description 5
- 238000009835 boiling Methods 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 238000004040 coloring Methods 0.000 description 5
- 239000012141 concentrate Substances 0.000 description 5
- 238000001816 cooling Methods 0.000 description 5
- 230000009849 deactivation Effects 0.000 description 5
- 230000018044 dehydration Effects 0.000 description 5
- 238000006297 dehydration reaction Methods 0.000 description 5
- 230000000857 drug effect Effects 0.000 description 5
- 235000019197 fats Nutrition 0.000 description 5
- 238000011010 flushing procedure Methods 0.000 description 5
- 238000005213 imbibition Methods 0.000 description 5
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 238000001728 nano-filtration Methods 0.000 description 5
- 238000009928 pasteurization Methods 0.000 description 5
- 102000004169 proteins and genes Human genes 0.000 description 5
- 108090000623 proteins and genes Proteins 0.000 description 5
- 238000010298 pulverizing process Methods 0.000 description 5
- 230000009467 reduction Effects 0.000 description 5
- 230000002000 scavenging effect Effects 0.000 description 5
- 238000004659 sterilization and disinfection Methods 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 238000005406 washing Methods 0.000 description 5
- 229920002683 Glycosaminoglycan Polymers 0.000 description 4
- 229930188089 Holothurin Natural products 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 238000011161 development Methods 0.000 description 4
- 230000018109 developmental process Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000002218 hypoglycaemic effect Effects 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 229960003080 taurine Drugs 0.000 description 4
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 3
- 239000004472 Lysine Substances 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 3
- 208000001132 Osteoporosis Diseases 0.000 description 3
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 3
- 150000001413 amino acids Chemical class 0.000 description 3
- 230000001093 anti-cancer Effects 0.000 description 3
- 230000036760 body temperature Effects 0.000 description 3
- 230000001605 fetal effect Effects 0.000 description 3
- 210000003754 fetus Anatomy 0.000 description 3
- MAWWITJOQDJRJF-ADBICINLSA-M holothurin Chemical compound [Na+].O[C@@H]1[C@@H](OC)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O[C@H]3[C@@H](OC[C@H]([C@@H]3O)OS([O-])(=O)=O)O[C@@H]3C([C@H]4[C@](C=5[C@H]([C@@]6(CC[C@]7(O)[C@](C)([C@H]8OC(C)(C)CC8)OC(=O)[C@@]76[C@@H](O)C=5)C)CC4)(C)CC3)(C)C)O[C@@H]2C)O)O[C@H](C)[C@H]1O MAWWITJOQDJRJF-ADBICINLSA-M 0.000 description 3
- 201000001881 impotence Diseases 0.000 description 3
- 229910052742 iron Inorganic materials 0.000 description 3
- 150000002632 lipids Chemical class 0.000 description 3
- 230000005906 menstruation Effects 0.000 description 3
- 239000011574 phosphorus Substances 0.000 description 3
- 229910052698 phosphorus Inorganic materials 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 235000002020 sage Nutrition 0.000 description 3
- 230000001256 tonic effect Effects 0.000 description 3
- -1 12 milligrams Chemical compound 0.000 description 2
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 description 2
- 239000004475 Arginine Substances 0.000 description 2
- 229920001287 Chondroitin sulfate Polymers 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000011149 active material Substances 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 210000004958 brain cell Anatomy 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 229940059329 chondroitin sulfate Drugs 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000035611 feeding Effects 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 235000004213 low-fat Nutrition 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 2
- 229910052753 mercury Inorganic materials 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 235000001968 nicotinic acid Nutrition 0.000 description 2
- 229960003512 nicotinic acid Drugs 0.000 description 2
- 239000011664 nicotinic acid Substances 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000001766 physiological effect Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 208000007442 rickets Diseases 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 150000003626 triacylglycerols Chemical class 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- 210000001835 viscera Anatomy 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- 239000011701 zinc Substances 0.000 description 2
- 229910052725 zinc Inorganic materials 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 241000186000 Bifidobacterium Species 0.000 description 1
- 208000003174 Brain Neoplasms Diseases 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 206010006242 Breast enlargement Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 229920002567 Chondroitin Polymers 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 description 1
- PNNNRSAQSRJVSB-SLPGGIOYSA-N Fucose Natural products C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C=O PNNNRSAQSRJVSB-SLPGGIOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 1
- SHZGCJCMOBCMKK-DHVFOXMCSA-N L-fucopyranose Chemical compound C[C@@H]1OC(O)[C@@H](O)[C@H](O)[C@@H]1O SHZGCJCMOBCMKK-DHVFOXMCSA-N 0.000 description 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 1
- 208000002454 Nasopharyngeal Carcinoma Diseases 0.000 description 1
- 206010061306 Nasopharyngeal cancer Diseases 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 208000002495 Uterine Neoplasms Diseases 0.000 description 1
- 206010046792 Uterine hypotonus Diseases 0.000 description 1
- 229930003451 Vitamin B1 Natural products 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000022972 amelogenesis Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000000476 body water Anatomy 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 230000011712 cell development Effects 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- DLGJWSVWTWEWBJ-HGGSSLSASA-N chondroitin Chemical compound CC(O)=N[C@@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1OC1[C@H](O)[C@H](O)C=C(C(O)=O)O1 DLGJWSVWTWEWBJ-HGGSSLSASA-N 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 210000004268 dentin Anatomy 0.000 description 1
- 230000013860 dentinogenesis Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000035487 diastolic blood pressure Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 201000010934 exostosis Diseases 0.000 description 1
- 230000001723 fibrinogenic effect Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000021588 free fatty acids Nutrition 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 239000003163 gonadal steroid hormone Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 210000005003 heart tissue Anatomy 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 201000010930 hyperostosis Diseases 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000003832 immune regulation Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 208000032839 leukemia Diseases 0.000 description 1
- 201000007270 liver cancer Diseases 0.000 description 1
- 208000014018 liver neoplasm Diseases 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 208000020816 lung neoplasm Diseases 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- 239000011572 manganese Substances 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 230000007102 metabolic function Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 201000011216 nasopharynx carcinoma Diseases 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 150000005830 nonesterified fatty acids Chemical class 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 235000020660 omega-3 fatty acid Nutrition 0.000 description 1
- 230000002188 osteogenic effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 230000036299 sexual function Effects 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 231100001055 skeletal defect Toxicity 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 201000000498 stomach carcinoma Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000035488 systolic blood pressure Effects 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 206010046766 uterine cancer Diseases 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
A provided immunity-enhancing sea cucumber oral liquid comprises the following active components: polyghaceseche, matrimony vine, laminaria japonica, bear gall, radix bupleuri, salvia miltiorrhiza, rhizoma polygonati, perilla seeds, cattail pollen, semen astragali complanati, coriolus versicolor, rhizome polygoni cuspidate, polygonum aviculare, andrographis paniculata nees and sea cucumber. The application method of the sea cucumber oral liquid comprises that adults take 5 mL of the oral liquid respectively at the morning and at the evening, calcium gluconate is taken when the elderly take the oral liquid, and vitamin C pulvis is taken when children take the oral liquid. The immunity-enhancing sea cucumber oral liquid is simple in ratio and reasonable in formula matching, and is capable of adjusting human body function, reducing blood pressure well, reducing blood sugar well, reducing blood fat well, and enhancing human body immunity.
Description
technical field:
The present invention relates to sea cucumber deep process technology field, relate in particular to a kind of holothurian oral liquid and using method thereof that strengthens immunity.
background technology:
Modern scientific research proves, sea cucumber nutrient is worth very high, in every hectogram, contain 15 grams, protein, 1 gram, fat, 0.4 gram, carbohydrate, 357 milligrams of calcium, 12 milligrams, phosphorus, 2.4 milligrams of iron, and vitamin B1, B2, more than the 50 kind of nutritional labeling useful to human physiological activity such as niacin, wherein protein content is up to more than 55%, it contains 18 seed amino acid taurines, chondroitin sulfate, stichopus japonicus mucopolysaccharide Multiple components, arginine is the main component that forms male sex's spermatid, it is again the primary raw material of synthesized human collagen, reparation after can promoting the regeneration of body cell and body impaired, can also improve the immunologic function of human body, promote longevity, eliminate tired.
Sea cucumber is extremely low containing cholesterol, is a kind of typical high protein, low fat, low cholesterol food.Add its fine and tender taste, be easy to digestion, so, be suitable for very much the elderly, children and the people that has a delicate constitution edible.Sea cucumber, because of extremely low containing cholesterol, is the food of a kind of typical high protein, low fat, low cholesterol.Because of fine and tender taste, be easy to digestion again, thus be applicable to very much the elderly and children, and the person of having a delicate constitution is edible.Taurine in sea cucumber, niacin etc.; there is the nervous system of adjusting, elimination fatigue fast; the effect of prevention skin aging; the taurine containing in sea cucumber in addition, lysine, methionine etc. almost do not have in vegetable food; the chondroitin sulfate containing in stichopus japonicus and stichopus japonicus mucopolysaccharide; by pharmacological evaluation, prove, to the growing of human body, anti-inflammatory skeletonization and prevention failure, promoting wound healing to suppress several cancer cells has special efficacy.Continuity is old and feeble, eliminate tired, improve immunity, the ability sea cucumber that strengthens resist the disease is rich in the natural precious active materials of kind more than 50 such as protein, mineral matter, vitamin, wherein acid mucopolysaccharide and chondroitin can obviously reduce the quantity of lipofuscin and skin proline in heart tissue, play the effect delaying senility.In sea cucumber body, 18 contained seed amino acids can strengthen the metabolic function of tissue, and enhanced machine body cell vigor, is suitable for the teenager in growing.Sea cucumber energy balance the body water balance, is suitable for the Ms of pregnancy period legs and feet edema.Sea cucumber can be eliminated tired, improves body immunity, strengthens the ability of human body resist the disease, is therefore applicable to very much often middle aged Ms and the man in fatigue state, the sub-health populations such as easy catching a cold, the elderly who has a delicate constitution and children.
Sea cucumber is not only delicious food, and is good tonic.Taurine in sea cucumber, lysine etc. almost do not have in vegetable food.The distinctive active material holothurin of sea cucumber, has significant inhibitory action to multiple fungi, has significant anti-inflammatory, osteogenic action, especially hepatitis, tuberculosis, diabetes, cardiovascular disease is had significant therapeutic effect.In brain healthy, practise midwifery lactagogue stichopus japonicus, contain two kinds of omega-3-polyunsaturated fatty acids (EPA and DHA).Wherein DHA plays vital effect to fetal brain cell development.Human brain is grown and is started from pregnant three month, and fetus obtains DHA and EPA from parent by placenta.If parent lacks DHA, can cause the Phospholipids of fetal brain cell not enough, affect the normal development of fetal central nervous system.DHA has significant benifit to strengthening memory and IQ, but also can make pregnant and lying-in women's breast enlargement, and milk is full.
Other functions of sea cucumber, as eliminated tumour, the anticancer heart that protects: contain a large amount of holothurins in the tissues such as body wall, internal organ and body of gland of sea cucumber, be again Sea Cucumber Glycosides.Holothurin is a kind of counterpoison, nontoxic to human-body safety, but growth and the transfer of energy inhibition tumor cell, effectively anti-cancer, anticancer, has been widely used in the treatment of liver cancer, lung cancer, cancer of the stomach, nasopharyngeal carcinoma, osteocarcinoma, lymph cancer, oophoroma, the cancer of the uterus, breast cancer, cancer of the brain leukaemia and hand postoperative patient clinically.Improve the frequent beche-de-mer of osteoporosis and can prevent children's rickets, adult's osteoporosis and hyperostosis.In gold most distinguished sea cucumber, the element such as abundant calcium, phosphorus, manganese, copper, germanium, silicon is to prevention Infant Rickets, adult's osteoporosis and to skeletal abnormality, deformity, and dentine and enamel development be bad special role.Enhancing development beche-de-mer helps lend some impetus to and grows.Abundant arginine, lysine, taurine, calcium, phosphorus, iodine, iron, zinc in sea cucumber; it is the important substance that human development grows up; they participate in the physiological activities such as the growing of human body itself, immune regulation, wound healing, reproductive development directly, in body energy deposit and running, play an important role.
Sea cucumber as in Chinese medicine simply, widely recorded, as, < < new compilation of materia medica > >: tonifying kidney and benefiting sperm, impotence is treated in establishing-Yang.The < < property of medicine is examined > >: fall fiery nourshing kidney, logical intestines are moisturized, except the timid disease of labor.< < food compatibility and incompatibility of drugs > >: kidney tonifying warp, beneficial marrow, dissolving phlegm saliva, takes the photograph urine, and impotence is treated in establishing-Yang, kills sore worm.The < < detailed outline > > that picks up any lost article from the road: raw hundred arteries and veins blood, control recurrent dysentery.< < book on Chinese herbal medicine is asked former > >: moisturizing viscera, grow smart Li Shui.< < occupies diet spectrum > > with breath: enriching yin, to enrich blood, and strong sun, moisturizes, menstruation regulating, nourishing the fetus, profit is produced.All postpartum,, should simmer food with ham or pig mutton.The modern Practical Chinese medicinal > of < < > nature and flavor: cold nature, taste is sweet, salty.Return lung, kidney, large intestine channel.Tonifying kidney and benefiting sperm; Enriching the blood to restore normal menstruation; Hemostasis.Cure mainly: essence and blood loss; Weak labor is timid; Impotence; Nocturnal emission; The dry constipation of intestines; Cough due to deficiency of the lung's spitting of blood, hematochezia, traumatism and bleeding.
Sea cucumber contains outside protein, calcium, potassium, zinc, iron, selenium, manganese isoreactivity material, and other active component is by holothurin and by amidohexose, uronic acid and fucose etc. form Stichopus Japonicus Acidic Mucopolysaccharide, separately containing 18 seed amino acids and do not contain cholesterol in sea cucumber body.Because sea cucumber is warm in nature, there is the strong sun of tonifying kidney and benefiting sperm, enriching yin, nourishing blood for moistening dryness, the menstruation regulating tonifying both YIN and YANG effects such as labor, nourishing the fetus profit product of dispelling.Can improve male endocrine ability, improve women's metabolism, promote sex hormone secretion ability, improve sexual function.From traditional Chinese medical science angle, kidney is basis of human body, as long as kidney goes wrong, be not only the problem that life quality reduces, and other organs can corresponding exhaustion.And palace product sea cucumber is to the main reinforcing kidney and strengthening resistance of the effect of human body, the element culturing fixed folder of namely as the saying goes.As long as human kidney is strong, each organ channels and collaterals all can be corresponding strong, and final people knows from experience more healthy, and the ability of resist the disease strengthens greatly.
The instructions of taking of sea cucumber, still take tonic as main at present, and tonic causes human absorptivity not enough, and the taboo of some culinary arts also usually causes the loss of sea cucumber nutrient composition, as, sea cucumber can not be cooked flavouring with vinegar.Therefore, there are on the market some sea cucumber deep processed products, as oral liquid, tablet, capsule, honey refining pill etc., in the process of deep processing, often adds Chinese patent drug to improve the absorptivity of product or to increase other auxiliary functions, but, some formula is unreasonable, for example, sea cucumber can not with Radix Glycyrrhizae compatibility etc.Therefore, it is simple that the present invention aims to provide a kind of proportioning, and prescription collocation is reasonable, balance the body function, and hypotensive, hypoglycemic, lipid-lowering effect is good, strengthens a kind of holothurian oral liquid and using method thereof that strengthens immunity of body immunity.
summary of the invention:
The object of the invention is to overcome the shortcoming existing in prior art, provide a kind of proportioning simple, prescription collocation rationally, balance the body function, hypotensive, hypoglycemic, lipid-lowering effect is good, strengthens a kind of holothurian oral liquid and using method thereof that strengthens immunity of body immunity.
To achieve these goals, the invention provides a kind of holothurian oral liquid that strengthens immunity, wherein, comprise following active component: radix polygonati officinalis, matrimony vine, kelp, bear gall, radix bupleuri, the red sage root, sealwort, perillaseed, cattail pollen, semen astragali complanati, rainbow conk, giant knotweed ， pivot holds, Herba Andrographitis, sea cucumber.
The using method of the holothurian oral liquid of described enhancing immunity, comprises the steps:
Per day for adults is respectively taken 5ml sooner or later,
When taking, the elderly adds calcium gluconae,
When taking, child adds vitamin C pulvis.
Strengthen the holothurian oral liquid of immunity, wherein, comprise according to the following active component of parts by weight configuration:
Radix polygonati officinalis 30-50 part, matrimony vine 20-40 part, kelp 20-40 part, bear gall 20-40 part, radix bupleuri 10-30 part, red sage root 10-30 part, sealwort 10-30 part, perillaseed 10-30 part, cattail pollen 10-30 part, semen astragali complanati 10-30 part, rainbow conk 10-30 part, giant knotweed 10-30 Fen ， pivot holds 10-30 part, Herba Andrographitis 10-30 part, sea cucumber 300-500 part.
Or, comprise according to the following active component of parts by weight configuration:
Radix polygonati officinalis 30-40 part, matrimony vine 20-30 part, kelp 20-30 part, bear gall 20-30 part, radix bupleuri 10-20 part, red sage root 10-20 part, sealwort 10-20 part, perillaseed 10-20 part, cattail pollen 10-20 part, semen astragali complanati 10-20 part, rainbow conk 10-20 part, giant knotweed 10-20 Fen ， pivot holds 10-20 part, Herba Andrographitis 10-20 part, sea cucumber 300-400 part.
Or, comprise according to the following active component of parts by weight configuration:
Radix polygonati officinalis 40-50 part, matrimony vine 30-40 part, kelp 30-40 part, bear gall 30-40 part, radix bupleuri 20-30 part, red sage root 20-30 part, sealwort 20-30 part, perillaseed 20-30 part, cattail pollen 20-30 part, semen astragali complanati 20-30 part, rainbow conk 20-30 part, giant knotweed 20-30 Fen ， pivot holds 20-30 part, Herba Andrographitis 20-30 part, sea cucumber 400-500 part.
Or, comprise according to the following active component of parts by weight configuration:
Radix polygonati officinalis 35-45 part, matrimony vine 25-35 part, kelp 25-35 part, bear gall 25-35 part, radix bupleuri 15-25 part, red sage root 15-25 part, sealwort 15-25 part, perillaseed 15-25 part, cattail pollen 15-25 part, semen astragali complanati 15-25 part, rainbow conk 15-25 part, giant knotweed 15-25 Fen ， pivot holds 15-25 part, Herba Andrographitis 15-25 part, sea cucumber 350-450 part.
Object to better implement the present invention, the present invention discloses again a kind of preparation method who strengthens the holothurian oral liquid of immunity, wherein, comprises the steps:
The step of A, cleaning: by radix polygonati officinalis, matrimony vine, kelp, bear gall, radix bupleuri, the red sage root, sealwort, perillaseed, cattail pollen, semen astragali complanati, rainbow conk, giant knotweed pivot holds, and Herba Andrographitis, according to medicinal part: root, stem, piece, leaf, sheet are classified, clean respectively, use tumbling-box type medicine-washing machine to clean, the cleaning rotating speed that the root of take is used as medicine is 100 revs/min, stem, piece, leaf, sheet clean successively the rotating speed reduction by 5% of root and clean, and scavenging period is controlled at 3-5 minute, avoid drug effect to run off;
The step of B, demulcen: the traditional Chinese medicinal components that steps A is cleaned up, use water injection type medicine processing device to carry out demulcen operation, demulcen makes the plant cell imbibition of dehydration, for abstraction process creates conditions;
The step of C, decoction: the sufficient traditional Chinese medicinal components of demulcen in step B is placed in to materials decoction device, extracts a not good liquor after heating decocts; Add again water and continue to decoct, extract two not good liquors; Add again water and continue to decoct, extract three not good liquors; By a not good liquor, two not good liquors, three not good liquors merge together, heat and concentrate, and obtain inspissated juice;
D, by step C gained inspissated juice, adding mass percent concentration is 95% ethanol, the amount adding is 10% of inspissated juice weight, to precipitate water-solubility impurity, adds additives, described additives are any one in flavouring, bacteriostatic agent, antioxidant or colouring agent, inspissated juice is uniformly dissolved, filters, use plate and frame filter press, millipore filter to filter, obtain filtrate
E, step D filtrate is heated, according to the different principle of boiling point, from filtrate, filtering ethanol and additives, obtain traditional Chinese medicine liquid, again after centrifugal filtration, embedding in tank body, sterilizing;
The step of F, sea cucumber deep processing: fresh and alive sea cucumbers, along belly from first to last complete section open, gill, impurity is cleaned up; Then carry out freeze drying, cryogenic temperature is-20 ~-25 ℃, and vacuum is 5-15Pa, and snap frozen 2-3h puts into pulverizer by the sea cucumber after freeze drying, pulverizes 10-30min, crosses 60 mesh sieves, obtains thick sea cucumber powder; Sea cucumber meal is carried out to ultramicro grinding by airslide disintegrating mill, and time 2-3h, obtains ultra micro sea cucumber powder; Then ultra micro sea cucumber powder is carried out to nanometer pulverizing by high speed shear ultrafine crusher, grinding time is 3-5h;
In container, add pure water, sea cucumber powder after nanometer is pulverized with water with 1: the dissolving of 5-10 mass ratio, obtain sea cucumber milk, take the compound protease of sea cucumber weight 0.3-0.4%, compound protease is the mixture of pepsic bromelain stomach, protease: the mass ratio=2:1 of bromelain, after using pure water that compound protease is dissolved, together with sea cucumber milk, put into enzymatic vessel, standing 1-2min in the microwave environment that is 500-1000w in intensity, carry out the operation of microwave enzymolysis, after enzymolysis completes, by enzymolysis liquid rapidly degree of intensification to 90 ℃ of enzyme 10-30min that go out, complete after the deactivation of enzyme, enzymatic vessel is stopped to heating, enzymolysis liquid is cooled to rapidly to normal temperature, enzymatic vessel purified rinse water, flushing liquor is put into enzymolysis liquid, enzymolysis liquid after cooling is first used to the centrifugal 20min of generic centrifuge, filter, get filtrate, the centrifugal 20min of low temperature ultrahigh speed, filters, and obtains filtrate, by filtrate by nanofiltration with except freshen, residue is crossed 100 mesh sieves, obtains sea cucumber extract.
G, filling step: step e gained herb liquid is mixed according to mass ratio 1-1.5:1-2 with step F gained sea cucumber extract, centrifugal filtration again, and sterilizing, the method that sterilizing adopts pasteurization to combine with microwave sterilization, filling after sterilizing, after filling and capping, 80-90 degree Celsius of sterilizing shifted out for 15 seconds.
Advantage of the present invention is: proportioning is simple, and prescription collocation is reasonable, balance the body function, and hypotensive, hypoglycemic, lipid-lowering effect is good, strengthens body immunity, is specially:
In sea cucumber extract, mix traditional Chinese medicine liquid and formed oral liquid of the present invention, oral liquid have taking dose little, absorb the advantages such as very fast, steady quality, easy to carry and use, easy preservation, be especially applicable to suitability for industrialized production.The present invention is to hypotensive, reducing blood lipid, and blood sugar decreasing effect is remarkable, can significantly improve body immunity, and by independent beche-de-mer or take more separately herb liquid, effect is all significantly increased.
the specific embodiment:
Strengthen a holothurian oral liquid for immunity, wherein, comprise following active component: radix polygonati officinalis, matrimony vine, kelp, bear gall, radix bupleuri, the red sage root, sealwort, perillaseed, cattail pollen, semen astragali complanati, rainbow conk, giant knotweed ， pivot holds, Herba Andrographitis, sea cucumber.
The using method of the holothurian oral liquid of described enhancing immunity, comprises the steps:
Per day for adults is respectively taken 5ml sooner or later,
When taking, the elderly adds calcium gluconae,
When taking, child adds vitamin C pulvis.
The holothurian oral liquid of enhancing immunity of the present invention, wherein, comprises according to the following active component of parts by weight configuration:
Radix polygonati officinalis 30-50 part, matrimony vine 20-40 part, kelp 20-40 part, bear gall 20-40 part, radix bupleuri 10-30 part, red sage root 10-30 part, sealwort 10-30 part, perillaseed 10-30 part, cattail pollen 10-30 part, semen astragali complanati 10-30 part, rainbow conk 10-30 part, giant knotweed 10-30 Fen ， pivot holds 10-30 part, Herba Andrographitis 10-30 part, sea cucumber 300-500 part.
Or, comprise according to the following active component of parts by weight configuration:
Radix polygonati officinalis 30-40 part, matrimony vine 20-30 part, kelp 20-30 part, bear gall 20-30 part, radix bupleuri 10-20 part, red sage root 10-20 part, sealwort 10-20 part, perillaseed 10-20 part, cattail pollen 10-20 part, semen astragali complanati 10-20 part, rainbow conk 10-20 part, giant knotweed 10-20 Fen ， pivot holds 10-20 part, Herba Andrographitis 10-20 part, sea cucumber 300-400 part.
Or, comprise according to the following active component of parts by weight configuration:
Radix polygonati officinalis 40-50 part, matrimony vine 30-40 part, kelp 30-40 part, bear gall 30-40 part, radix bupleuri 20-30 part, red sage root 20-30 part, sealwort 20-30 part, perillaseed 20-30 part, cattail pollen 20-30 part, semen astragali complanati 20-30 part, rainbow conk 20-30 part, giant knotweed 20-30 Fen ， pivot holds 20-30 part, Herba Andrographitis 20-30 part, sea cucumber 400-500 part.
Or, comprise according to the following active component of parts by weight configuration:
Radix polygonati officinalis 35-45 part, matrimony vine 25-35 part, kelp 25-35 part, bear gall 25-35 part, radix bupleuri 15-25 part, red sage root 15-25 part, sealwort 15-25 part, perillaseed 15-25 part, cattail pollen 15-25 part, semen astragali complanati 15-25 part, rainbow conk 15-25 part, giant knotweed 15-25 Fen ， pivot holds 15-25 part, Herba Andrographitis 15-25 part, sea cucumber 350-450 part.
Object to better implement the present invention, the present invention discloses again a kind of preparation method who strengthens the holothurian oral liquid of immunity, wherein, comprises the steps:
The step of A, cleaning: by radix polygonati officinalis, matrimony vine, kelp, bear gall, radix bupleuri, the red sage root, sealwort, perillaseed, cattail pollen, semen astragali complanati, rainbow conk, giant knotweed pivot holds, and Herba Andrographitis, according to medicinal part: root, stem, piece, leaf, sheet are classified, clean respectively, use tumbling-box type medicine-washing machine to clean, the cleaning rotating speed that the root of take is used as medicine is 100 revs/min, stem, piece, leaf, sheet clean successively the rotating speed reduction by 5% of root and clean, and scavenging period is controlled at 3-5 minute, avoid drug effect to run off;
The step of B, demulcen: the traditional Chinese medicinal components that steps A is cleaned up, use water injection type medicine processing device to carry out demulcen operation, demulcen makes the plant cell imbibition of dehydration, for abstraction process creates conditions;
The step of C, decoction: the sufficient traditional Chinese medicinal components of demulcen in step B is placed in to materials decoction device, extracts a not good liquor after heating decocts; Add again water and continue to decoct, extract two not good liquors; Add again water and continue to decoct, extract three not good liquors; By a not good liquor, two not good liquors, three not good liquors merge together, heat and concentrate, and obtain inspissated juice;
D, by step C gained inspissated juice, adding mass percent concentration is 95% ethanol, the amount adding is 10% of inspissated juice weight, to precipitate water-solubility impurity, adds additives, described additives are any one in flavouring, bacteriostatic agent, antioxidant or colouring agent, inspissated juice is uniformly dissolved, filters, use plate and frame filter press, millipore filter to filter, obtain filtrate
E, step D filtrate is heated, according to the different principle of boiling point, from filtrate, filtering ethanol and additives, obtain traditional Chinese medicine liquid, again after centrifugal filtration, embedding in tank body, sterilizing;
The step of F, sea cucumber deep processing: fresh and alive sea cucumbers, along belly from first to last complete section open, gill, impurity is cleaned up; Then carry out freeze drying, cryogenic temperature is-20 ~-25 ℃, and vacuum is 5-15Pa, and snap frozen 2-3h puts into pulverizer by the sea cucumber after freeze drying, pulverizes 10-30min, crosses 60 mesh sieves, obtains thick sea cucumber powder; Sea cucumber meal is carried out to ultramicro grinding by airslide disintegrating mill, and time 2-3h, obtains ultra micro sea cucumber powder; Then ultra micro sea cucumber powder is carried out to nanometer pulverizing by high speed shear ultrafine crusher, grinding time is 3-5h;
In container, add pure water, sea cucumber powder after nanometer is pulverized with water with 1: the dissolving of 5-10 mass ratio, obtain sea cucumber milk, take the compound protease of sea cucumber weight 0.3-0.4%, compound protease is the mixture of pepsic bromelain stomach, protease: the mass ratio=2:1 of bromelain, after using pure water that compound protease is dissolved, together with sea cucumber milk, put into enzymatic vessel, standing 1-2min in the microwave environment that is 500-1000w in intensity, carry out the operation of microwave enzymolysis, after enzymolysis completes, by enzymolysis liquid rapidly degree of intensification to 90 ℃ of enzyme 10-30min that go out, complete after the deactivation of enzyme, enzymatic vessel is stopped to heating, enzymolysis liquid is cooled to rapidly to normal temperature, enzymatic vessel purified rinse water, flushing liquor is put into enzymolysis liquid, enzymolysis liquid after cooling is first used to the centrifugal 20min of generic centrifuge, filter, get filtrate, the centrifugal 20min of low temperature ultrahigh speed, filters, and obtains filtrate, by filtrate by nanofiltration with except freshen, residue is crossed 100 mesh sieves, obtains sea cucumber extract.
G, filling step: step e gained herb liquid is mixed according to mass ratio 1-1.5:1-2 with step F gained sea cucumber extract, centrifugal filtration again, and sterilizing, the method that sterilizing adopts pasteurization to combine with microwave sterilization, filling after sterilizing, after filling and capping, 80-90 degree Celsius of sterilizing shifted out for 15 seconds.
Object lesson 1
50 parts of radix polygonati officinalis, 40 parts of matrimony vines, 40 parts of kelps, 40 parts of bear galls, 30 parts of radix bupleuri, 30 parts of the reds sage root, 30 parts of sealworts, 30 parts of perillaseeds, 30 parts of cattail pollens, 30 parts of semen astragali complanatis, 30 parts of rainbow conk, giant knotweed 30 Fen ， pivots hold 30 parts, 30 parts of Herba Andrographitis, 500 parts of sea cucumbers.
The step of A, cleaning: by radix polygonati officinalis, matrimony vine, kelp, bear gall, radix bupleuri, the red sage root, sealwort, perillaseed, cattail pollen, semen astragali complanati, rainbow conk, giant knotweed pivot holds, and Herba Andrographitis, according to medicinal part: root, stem, piece, leaf, sheet are classified, clean respectively, use tumbling-box type medicine-washing machine to clean, the cleaning rotating speed that the root of take is used as medicine is 100 revs/min, stem, piece, leaf, sheet clean successively the rotating speed reduction by 5% of root and clean, and scavenging period is controlled at 3-5 minute, avoid drug effect to run off;
The step of B, demulcen: the traditional Chinese medicinal components that steps A is cleaned up, use water injection type medicine processing device to carry out demulcen operation, demulcen makes the plant cell imbibition of dehydration, for abstraction process creates conditions;
The step of C, decoction: the sufficient traditional Chinese medicinal components of demulcen in step B is placed in to materials decoction device, extracts a not good liquor after heating decocts; Add again water and continue to decoct, extract two not good liquors; Add again water and continue to decoct, extract three not good liquors; By a not good liquor, two not good liquors, three not good liquors merge together, heat and concentrate, and obtain inspissated juice;
D, by step C gained inspissated juice, adding mass percent concentration is 95% ethanol, the amount adding is 10% of inspissated juice weight, to precipitate water-solubility impurity, adds additives, described additives are any one in flavouring, bacteriostatic agent, antioxidant or colouring agent, inspissated juice is uniformly dissolved, filters, use plate and frame filter press, millipore filter to filter, obtain filtrate
E, step D filtrate is heated, according to the different principle of boiling point, from filtrate, filtering ethanol and additives, obtain traditional Chinese medicine liquid, again after centrifugal filtration, embedding in tank body, sterilizing;
The step of F, sea cucumber deep processing: fresh and alive sea cucumbers, along belly from first to last complete section open, gill, impurity is cleaned up; Then carry out freeze drying, cryogenic temperature is-20 ~-25 ℃, and vacuum is 5-15Pa, and snap frozen 2-3h puts into pulverizer by the sea cucumber after freeze drying, pulverizes 10-30min, crosses 60 mesh sieves, obtains thick sea cucumber powder; Sea cucumber meal is carried out to ultramicro grinding by airslide disintegrating mill, and time 2-3h, obtains ultra micro sea cucumber powder; Then ultra micro sea cucumber powder is carried out to nanometer pulverizing by high speed shear ultrafine crusher, grinding time is 3-5h;
In container, add pure water, sea cucumber powder after nanometer is pulverized with water with 1: the dissolving of 5-10 mass ratio, obtain sea cucumber milk, take the compound protease of sea cucumber weight 0.3-0.4%, compound protease is the mixture of pepsic bromelain stomach, protease: the mass ratio=2:1 of bromelain, after using pure water that compound protease is dissolved, together with sea cucumber milk, put into enzymatic vessel, standing 1-2min in the microwave environment that is 500-1000w in intensity, carry out the operation of microwave enzymolysis, after enzymolysis completes, by enzymolysis liquid rapidly degree of intensification to 90 ℃ of enzyme 10-30min that go out, complete after the deactivation of enzyme, enzymatic vessel is stopped to heating, enzymolysis liquid is cooled to rapidly to normal temperature, enzymatic vessel purified rinse water, flushing liquor is put into enzymolysis liquid, enzymolysis liquid after cooling is first used to the centrifugal 20min of generic centrifuge, filter, get filtrate, the centrifugal 20min of low temperature ultrahigh speed, filters, and obtains filtrate, by filtrate by nanofiltration with except freshen, residue is crossed 100 mesh sieves, obtains sea cucumber extract.
G, filling step: step e gained herb liquid is mixed according to mass ratio 1-1.5:1-2 with step F gained sea cucumber extract, centrifugal filtration again, and sterilizing, the method that sterilizing adopts pasteurization to combine with microwave sterilization, filling after sterilizing, after filling and capping, 80-90 degree Celsius of sterilizing shifted out for 15 seconds.
Example 2
30 parts of radix polygonati officinalis, 20 parts of matrimony vines, 20 parts of kelps, 20 parts of bear galls, 10 parts of radix bupleuri, 10 parts of the reds sage root, 10 parts of sealworts, 10 parts of perillaseeds, 10 parts of cattail pollens, 10 parts of semen astragali complanatis, 10 parts of rainbow conk, giant knotweed 10 Fen ， pivots hold 10 parts, 10 parts of Herba Andrographitis, 300 parts of sea cucumbers.
The step of A, cleaning: by radix polygonati officinalis, matrimony vine, kelp, bear gall, radix bupleuri, the red sage root, sealwort, perillaseed, cattail pollen, semen astragali complanati, rainbow conk, giant knotweed pivot holds, and Herba Andrographitis, according to medicinal part: root, stem, piece, leaf, sheet are classified, clean respectively, use tumbling-box type medicine-washing machine to clean, the cleaning rotating speed that the root of take is used as medicine is 100 revs/min, stem, piece, leaf, sheet clean successively the rotating speed reduction by 5% of root and clean, and scavenging period is controlled at 3-5 minute, avoid drug effect to run off;
The step of B, demulcen: the traditional Chinese medicinal components that steps A is cleaned up, use water injection type medicine processing device to carry out demulcen operation, demulcen makes the plant cell imbibition of dehydration, for abstraction process creates conditions;
The step of C, decoction: the sufficient traditional Chinese medicinal components of demulcen in step B is placed in to materials decoction device, extracts a not good liquor after heating decocts; Add again water and continue to decoct, extract two not good liquors; Add again water and continue to decoct, extract three not good liquors; By a not good liquor, two not good liquors, three not good liquors merge together, heat and concentrate, and obtain inspissated juice;
D, by step C gained inspissated juice, adding mass percent concentration is 95% ethanol, the amount adding is 10% of inspissated juice weight, to precipitate water-solubility impurity, adds additives, described additives are any one in flavouring, bacteriostatic agent, antioxidant or colouring agent, inspissated juice is uniformly dissolved, filters, use plate and frame filter press, millipore filter to filter, obtain filtrate
E, step D filtrate is heated, according to the different principle of boiling point, from filtrate, filtering ethanol and additives, obtain traditional Chinese medicine liquid, again after centrifugal filtration, embedding in tank body, sterilizing;
The step of F, sea cucumber deep processing: fresh and alive sea cucumbers, along belly from first to last complete section open, gill, impurity is cleaned up; Then carry out freeze drying, cryogenic temperature is-20 ~-25 ℃, and vacuum is 5-15Pa, and snap frozen 2-3h puts into pulverizer by the sea cucumber after freeze drying, pulverizes 10-30min, crosses 60 mesh sieves, obtains thick sea cucumber powder; Sea cucumber meal is carried out to ultramicro grinding by airslide disintegrating mill, and time 2-3h, obtains ultra micro sea cucumber powder; Then ultra micro sea cucumber powder is carried out to nanometer pulverizing by high speed shear ultrafine crusher, grinding time is 3-5h;
In container, add pure water, sea cucumber powder after nanometer is pulverized with water with 1: the dissolving of 5-10 mass ratio, obtain sea cucumber milk, take the compound protease of sea cucumber weight 0.3-0.4%, compound protease is the mixture of pepsic bromelain stomach, protease: the mass ratio=2:1 of bromelain, after using pure water that compound protease is dissolved, together with sea cucumber milk, put into enzymatic vessel, standing 1-2min in the microwave environment that is 500-1000w in intensity, carry out the operation of microwave enzymolysis, after enzymolysis completes, by enzymolysis liquid rapidly degree of intensification to 90 ℃ of enzyme 10-30min that go out, complete after the deactivation of enzyme, enzymatic vessel is stopped to heating, enzymolysis liquid is cooled to rapidly to normal temperature, enzymatic vessel purified rinse water, flushing liquor is put into enzymolysis liquid, enzymolysis liquid after cooling is first used to the centrifugal 20min of generic centrifuge, filter, get filtrate, the centrifugal 20min of low temperature ultrahigh speed, filters, and obtains filtrate, by filtrate by nanofiltration with except freshen, residue is crossed 100 mesh sieves, obtains sea cucumber extract.
G, filling step: step e gained herb liquid is mixed according to mass ratio 1-1.5:1-2 with step F gained sea cucumber extract, centrifugal filtration again, and sterilizing, the method that sterilizing adopts pasteurization to combine with microwave sterilization, filling after sterilizing, after filling and capping, 80-90 degree Celsius of sterilizing shifted out for 15 seconds.
Example 3
40 parts of radix polygonati officinalis, 30 parts of matrimony vines, 30 parts of kelps, 30 parts of bear galls, 20 parts of radix bupleuri, 20 parts of the reds sage root, 20 parts of sealworts, 20 parts of perillaseeds, 20 parts of cattail pollens, 20 parts of semen astragali complanatis, 20 parts of rainbow conk, giant knotweed 20 Fen ， pivots hold 20 parts, 20 parts of Herba Andrographitis, 400 parts of sea cucumbers.
The step of A, cleaning: by radix polygonati officinalis, matrimony vine, kelp, bear gall, radix bupleuri, the red sage root, sealwort, perillaseed, cattail pollen, semen astragali complanati, rainbow conk, giant knotweed pivot holds, and Herba Andrographitis, according to medicinal part: root, stem, piece, leaf, sheet are classified, clean respectively, use tumbling-box type medicine-washing machine to clean, the cleaning rotating speed that the root of take is used as medicine is 100 revs/min, stem, piece, leaf, sheet clean successively the rotating speed reduction by 5% of root and clean, and scavenging period is controlled at 3-5 minute, avoid drug effect to run off;
The step of B, demulcen: the traditional Chinese medicinal components that steps A is cleaned up, use water injection type medicine processing device to carry out demulcen operation, demulcen makes the plant cell imbibition of dehydration, for abstraction process creates conditions;
The step of C, decoction: the sufficient traditional Chinese medicinal components of demulcen in step B is placed in to materials decoction device, extracts a not good liquor after heating decocts; Add again water and continue to decoct, extract two not good liquors; Add again water and continue to decoct, extract three not good liquors; By a not good liquor, two not good liquors, three not good liquors merge together, heat and concentrate, and obtain inspissated juice;
D, by step C gained inspissated juice, adding mass percent concentration is 95% ethanol, the amount adding is 10% of inspissated juice weight, to precipitate water-solubility impurity, adds additives, described additives are any one in flavouring, bacteriostatic agent, antioxidant or colouring agent, inspissated juice is uniformly dissolved, filters, use plate and frame filter press, millipore filter to filter, obtain filtrate
E, step D filtrate is heated, according to the different principle of boiling point, from filtrate, filtering ethanol and additives, obtain traditional Chinese medicine liquid, again after centrifugal filtration, embedding in tank body, sterilizing;
The step of F, sea cucumber deep processing: fresh and alive sea cucumbers, along belly from first to last complete section open, gill, impurity is cleaned up; Then carry out freeze drying, cryogenic temperature is-20 ~-25 ℃, and vacuum is 5-15Pa, and snap frozen 2-3h puts into pulverizer by the sea cucumber after freeze drying, pulverizes 10-30min, crosses 60 mesh sieves, obtains thick sea cucumber powder; Sea cucumber meal is carried out to ultramicro grinding by airslide disintegrating mill, and time 2-3h, obtains ultra micro sea cucumber powder; Then ultra micro sea cucumber powder is carried out to nanometer pulverizing by high speed shear ultrafine crusher, grinding time is 3-5h;
In container, add pure water, sea cucumber powder after nanometer is pulverized with water with 1: the dissolving of 5-10 mass ratio, obtain sea cucumber milk, take the compound protease of sea cucumber weight 0.3-0.4%, compound protease is the mixture of pepsic bromelain stomach, protease: the mass ratio=2:1 of bromelain, after using pure water that compound protease is dissolved, together with sea cucumber milk, put into enzymatic vessel, standing 1-2min in the microwave environment that is 500-1000w in intensity, carry out the operation of microwave enzymolysis, after enzymolysis completes, by enzymolysis liquid rapidly degree of intensification to 90 ℃ of enzyme 10-30min that go out, complete after the deactivation of enzyme, enzymatic vessel is stopped to heating, enzymolysis liquid is cooled to rapidly to normal temperature, enzymatic vessel purified rinse water, flushing liquor is put into enzymolysis liquid, enzymolysis liquid after cooling is first used to the centrifugal 20min of generic centrifuge, filter, get filtrate, the centrifugal 20min of low temperature ultrahigh speed, filters, and obtains filtrate, by filtrate by nanofiltration with except freshen, residue is crossed 100 mesh sieves, obtains sea cucumber extract.
G, filling step: step e gained herb liquid is mixed according to mass ratio 1-1.5:1-2 with step F gained sea cucumber extract, centrifugal filtration again, and sterilizing, the method that sterilizing adopts pasteurization to combine with microwave sterilization, filling after sterilizing, after filling and capping, 80-90 degree Celsius of sterilizing shifted out for 15 seconds.
Data comparison:
By step e gained traditional Chinese medicine liquid, three high crowd 50 people take, as A group,
By step F gained sea cucumber extract, three high crowd 50 people take, as B group
Three high crowd 50 people take the holothurian oral liquid that traditional tradition strengthens immunity, and for example " the disclosed oral liquid of patent application 201210420808.6 " as C group,
Three high crowd's 50 people's beche-de-mers, one for each person every day, as D group.
Embodiment 1 takes for three high crowd 50 people, as E group.
Embodiment 2 takes for three high crowd 50 people, as F group.
Embodiment 3 takes for three high crowd 50 people, as G group.
Take continuously after 50 days, each one body status data is as follows: (people's health index mainly comprises the indexes such as body temperature, blood pressure, blood sugar, blood viscosity, blood fat, heart rate, and normal person's index is:
Body temperature, adult's body temperature temperature is 36.5-37 degree (oxter).
Blood pressure, adult's blood pressure should be systolic pressure 90-140 mercury column, diastolic pressure 60-90 mercury column.
Blood sugar, fasting blood-glucose normal value is below 6.1 or 109 milligrams, the normal value of blood sugar is below 7.8 or 140 milligrams after meal.
Blood viscosity is the abbreviation of blood viscosity, it is one of index of reflection viscosity of blood, the factor that affects blood viscousness mainly contains erythrocyte aggregation and morphotropism, packed cell volume, size and geometric, Blood Cholesterol, triglycerides and fibrinogenic content etc.
Blood fat, the lipid material in blood plasma is called blood fat, comprises triglycerides, phosphatide, cholesterol, cholesteryl ester and non-esterified fatty acid etc.
Heart rate, about 60-80 time of general adult's heartbeat per minute, average out to 75 times, children's heart rate is very fast.Pulse, is grown up 60-70 time per minute.Breathe the breathing per minute 14-18 time of being grown up)
Immunity comparison
Select the holothurian oral liquid of 10 small white mouse feeding tradition enhancing immunity as a control group,
Select 10 small white mouse feedings the present invention group as a comparison.
Be compared as follows:
Wherein, the absorption of comparative group calcium and mineral matter is fast, and propagation Bifidobacterium, lactic acid bacteria number is many, and the index of blood fat, blood sugar, adjusting cholesterol is low compared with control group.3-5 is placed in dark environment and the environment that is exposed to the sun repeatedly in day, the control group probability of catching an illness is large, so comparative group immunity is strong.
So advantage of the present invention is: proportioning is simple, prescription collocation is reasonable, balance the body function, and hypotensive, hypoglycemic, lipid-lowering effect is good, strengthens body immunity, is specially:
In sea cucumber extract, mix traditional Chinese medicine liquid and formed oral liquid of the present invention, oral liquid have taking dose little, absorb the advantages such as very fast, steady quality, easy to carry and use, easy preservation, be especially applicable to suitability for industrialized production.The present invention is to hypotensive, reducing blood lipid, and blood sugar decreasing effect is remarkable, can significantly improve body immunity, and by independent beche-de-mer or take more separately herb liquid, effect is all significantly increased.
Claims (2)
1. a holothurian oral liquid that strengthens immunity, is characterized in that, comprises following active component: radix polygonati officinalis, and matrimony vine, kelp, bear gall, radix bupleuri, the red sage root, sealwort, perillaseed, cattail pollen, semen astragali complanati, rainbow conk, giant knotweed, pivot holds, Herba Andrographitis, sea cucumber.
2. strengthen as claimed in claim 1 a using method for the holothurian oral liquid of immunity, it is characterized in that, comprise the steps:
Per day for adults is respectively taken 5ml sooner or later,
When taking, the elderly adds calcium gluconae,
When taking, child adds vitamin C pulvis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310490940.9A CN103610112A (en) | 2013-10-20 | 2013-10-20 | Immunity-enhancing sea cucumber oral liquid and application method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310490940.9A CN103610112A (en) | 2013-10-20 | 2013-10-20 | Immunity-enhancing sea cucumber oral liquid and application method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103610112A true CN103610112A (en) | 2014-03-05 |
Family
ID=50160848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310490940.9A Pending CN103610112A (en) | 2013-10-20 | 2013-10-20 | Immunity-enhancing sea cucumber oral liquid and application method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103610112A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104643144A (en) * | 2015-03-23 | 2015-05-27 | 万雄集团股份有限公司 | Sea cucumber traditional Chinese medicine decoction for improving male sexual disfunction and preparation method of sea cucumber traditional Chinese medicine decoction |
| CN111820386A (en) * | 2020-06-24 | 2020-10-27 | 青岛越群生物科技有限公司 | Sea cucumber oral liquid and preparation method thereof |
-
2013
- 2013-10-20 CN CN201310490940.9A patent/CN103610112A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104643144A (en) * | 2015-03-23 | 2015-05-27 | 万雄集团股份有限公司 | Sea cucumber traditional Chinese medicine decoction for improving male sexual disfunction and preparation method of sea cucumber traditional Chinese medicine decoction |
| CN111820386A (en) * | 2020-06-24 | 2020-10-27 | 青岛越群生物科技有限公司 | Sea cucumber oral liquid and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103610035A (en) | Preparation method for sea cucumber nutritional oral liquid | |
| CN105296584A (en) | Preparation method of marine biological health care peptide preparation | |
| CN104873763A (en) | Health-care product for conditioning Qi deficiency constitution | |
| CN103610072A (en) | Preparation method for blood-sugar-reducing sea cucumber oral liquid | |
| CN103610077A (en) | Sea cucumber capsule | |
| CN106983073A (en) | A kind of health-maintaining noodles containing astaxanthin and preparation method thereof | |
| CN103610076A (en) | Preparation method for sea cucumber capsule | |
| CN103610112A (en) | Immunity-enhancing sea cucumber oral liquid and application method thereof | |
| CN104856036A (en) | Health care medicated diet for treating iron-deficiency anemia and preparation method of health care medicated diet | |
| CN103610068A (en) | Preparation method for blood-fat-reducing sea cucumber oral liquid | |
| CN103610069A (en) | Blood-sugar-reducing sea cucumber oral liquid | |
| KR101160196B1 (en) | Functional food and method of preparing thereof | |
| CN103610116A (en) | Preparation method for sea cucumber nutritional capsule | |
| CN103610033A (en) | Immunity-enhancing sea cucumber oral liquid | |
| CN103610067A (en) | Preparation method for immunity-enhancing sea cucumber oral liquid | |
| CN103610117A (en) | Sea cucumber nutritional oral liquid | |
| CN103610070A (en) | Blood-fat-reducing sea cucumber oral liquid and application method thereof | |
| CN103610071A (en) | Preparation method for blood-pressure-reducing sea cucumber oral liquid | |
| CN103610073A (en) | Sea cucumber oral liquid and application method thereof | |
| CN103585456A (en) | Sea cucumber chewable tablet | |
| CN103611058A (en) | Sea cucumber capsule and application method thereof | |
| CN103610998A (en) | Sea cucumber nutritional capsule | |
| CN103610118A (en) | Sea cucumber nutritional oral liquid and application method thereof | |
| CN103610113A (en) | Blood-pressure-reducing sea cucumber oral liquid and application method thereof | |
| CN103610953A (en) | Preparation method for yin-nourishing yang-fortifying sea cucumber capsule |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140305 |
|
| WD01 | Invention patent application deemed withdrawn after publication |