CN104436009B - Liver cancer medicine - Google Patents

Liver cancer medicine Download PDF

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Publication number
CN104436009B
CN104436009B CN201410579022.8A CN201410579022A CN104436009B CN 104436009 B CN104436009 B CN 104436009B CN 201410579022 A CN201410579022 A CN 201410579022A CN 104436009 B CN104436009 B CN 104436009B
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radix
liver cancer
chinese
root
liver
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CN104436009A (en
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喻可安
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/902Sparganiaceae (Bur-reed family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The present invention is a kind of Chinese medicine preparation for treating liver cancer, its bulk drug be by:The taste Chinese medicine of inular flower, marine alga, kelp, Chinese violet, dandelion, day fourth, Rhizoma Sparganii, oldenlandia diffusa, edible tulip, vomiting nut, air potato, oyster, the red sage root, the radix paeoniae rubrathe, stringy stonecrop, felwort, radix scutellariae, radix bupleuri, the Radix Codonopsis fruit of Chinese magnoliavine, ginseng, the tuber of pinellia, honey-fried licorice root, Radix Isatidis, honeysuckle stem, root of herbaceous peony etc. 50 forms.Liver cancer early stage non-evident sympton, therefore easy delay diagnosis, it is when there is symptom to belong to late periods more, common clinical manifestation is hepatalgia, liver progressive enlargement, low-heat, jaundice, abdominal distension, anorexia, nausea and vomiting, become thin weak, oedema and progressive anaemia etc., because it is found that rear progress is rapid, the death rate is high, therefore seriously endangers the life and health of people.Liver cancer, which is liver blood stasis, the stagnation of the circulation of vital energy, phlegm is solidifying, evil poison knot is poly- forms.The present invention has the function that clearing heat and detoxicating, promoting blood circulation and removing blood stasis, promoting the circulation of qi resolving sputum, softening and resolving hard mass, righting, invigorating spleen and reinforcing stomach, anticancer and kills cancer cell, is protruded for treating liver cancer efficacy.

Description

Liver cancer medicine
(1) the technical field present invention is a kind of Chinese medicine preparation for treating liver cancer.
(2) background technology liver cancer is one of common malignant tumour in China, liver cancer early stage non-evident sympton, therefore easily delay Diagnosis, more category late periods when there is symptom, common clinical manifestation are hepatalgia, liver progressive enlargement, low-heat, jaundice, Abdominal distension, anorexia, nausea and vomiting, become thin weak, oedema and progressive anaemia etc., because it is found that rear progress is rapid, the death rate Height, therefore seriously endanger the life and health of people.The pathogenic factor of liver cancer:From the viewpoint of doctor trained in Western medicine, pathogenic factor is not yet Clearly, it is now recognized that the morbidity of fall ill closely related 1, chronic hepatic diseases virus hepatitis and the liver cancer of following factor and liver cancer It is relevant, it is B-mode in hepatitis, it is the main Types of induced hepatocellular carcinoma.The morbidity of cirrhosis and liver cancer is also closely related, shows hepatitis The liver cancer of one cirrhosis one has a close contact in path, and mainly relevant with hepatitis B 2, chemical pathogenic material is as yellow bent The chemical substances such as mycin, nitrous acid amine, carbon tetrachloride, azobenzene can induced hepatocellular carcinoma.3rd, other malnutritive, heredity, certain A little liver parasites also can induced hepatocellular carcinoma;Liver cancer that therefrom medical science viewpoint thinks that pathogenesis of cancer reason is complex ... is liver blood Silt, the stagnation of the circulation of vital energy, phlegm is solidifying, evil poison knot is poly- forms.
(3) content of the invention present invention is by bulk drug:The 30 portions of stir-fry Fructus Sophorae 10 portions of (grinding) 15 portions of inular flower marine algas of oriental wormwood 20 parts of 20 parts of kelp, 15 parts of turtle shell (vinegar system), 60 parts of selfheal, 30 parts of Chinese violet, 30 parts of dandelion, 20 parts of day fourth, 20 parts of Rhizoma Sparganiis 20 parts of curcuma zedoary, 60 parts of oldenlandia diffusa, 30 parts of field pennycress, 6 parts of edible tulip, 4 parts of vomiting nut, 0.3 part of Chinese blister beetle, 30 parts of nidus vespae 30 portions of sarcandra, 30 portions of air potato, 15 portions of semiaquilegia adoxoides, 30 portions of oyster, 20 portions of root tuber of aromatic turmeric, 20 portions of the red sage root, 20 portions of the radix paeoniae rubrathe, 15 parts of ground bettle 0.04 part of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), 40 parts of stringy stonecrop, 40 parts of hypericum japonicum, 12 parts of felwort, 15 parts of radix scutellariae, 15 parts of radix bupleuri, 30 parts of Radix Codonopsis 30 parts of the Radix Astragali, 30 parts of the fruit of glossy privet, 10 parts of the fruit of Chinese magnoliavine, 20 parts of ginseng, 20 parts of the bighead atractylodes rhizome, 20 parts of barrenwort, 20 parts of Poria cocos, 20 parts of the tuber of pinellia 20 parts of dried orange peel, 15 parts of honey-fried licorice root, 20 parts of folium isatidis, 20 parts of Sagina subulata, 30 parts of Radix Isatidis, 30 parts of honeysuckle stem, 18 parts of Ligusticum wallichiis of Radix Angelicae Sinensis 18 portions of 24 parts of root of herbaceous peonys are by weight composition.Liver cancer, which is liver blood stasis, the stagnation of the circulation of vital energy, phlegm is solidifying, evil poison knot is poly- forms.
Wherein:Oldenlandia diffusa Radix Isatidis honeysuckle stem selfheal day fourth Chinese violet dandelion field pennycress semiaquilegia adoxoides horse Money Chinese blister beetle nidus vespae sarcandra air potato felwort radix scutellariae folium isatidis Sagina subulata stringy stonecrop hypericum japonicum is clearing heat and detoxicating, Attack poison and reached the purpose for mitigating symptom, while oldenlandia diffusa vomiting nut nidus vespae sarcandra air potato semiaquilegia adoxoides Chinese blister beetle has The effect of anticancer, folium isatidis Sagina subulata play the role of to make HBsAg turn out cloudy, and oriental wormwood, which fries the Fructus Sophorae and controls hepatitis, to disappear jaundice, Felwort radix bupleuri radix scutellariae stringy stonecrop hypericum japonicum plays the role of transaminase lowering, and turtle shell red sage root root tuber of aromatic turmeric oyster is swollen for liver and spleen Have the effect of soft contracting liver and spleen greatly, Rhizoma Sparganii curcuma zedoary radix paeoniae rubrathe red sage and chuanxiong rhizome Radix Angelicae Sinensis ground bettle Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) it is promoting blood circulation and removing blood stasis from And play a part of eliminating lump and relieve pain, especially Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) gathers to Post operation and late tumor pain imitates fast and continues Time is grown, and Rhizoma Sparganii, curcuma zedoary play the role of directly to kill to cancer cell and therefore to cancer inhibitting and killing cell and prevent that it from spreading and transfer is equal Play the role of important, marine alga kelp tuber of pinellia oyster edible tulip inular flower reducing phlegm and resolving masses has been subsided a swelling block, and turtle shell enriching yin softening hard masses dissipate Knot, root tuber of aromatic turmeric radix bupleuri dispersing stagnated hepatoqi can reach the purpose of promoting flow of qi and blood circulation eliminating stagnation to stop pain, the ginseng Radix Astragali barrenwort fruit of glossy privet bighead atractylodes rhizome Radix Angelicae Sinensis righting qi-restoratives is the important method for the treatment of cancer, while the ginseng fruit of glossy privet is for white caused by chemotherapy and radiotherapy Blood cell, which declines, its elevated effect that makes, and bighead atractylodes rhizome Radix Astragali fruit of Chinese magnoliavine Radix Angelicae Sinensis can protect liver to improve resistance against diseases.Ginseng Fu Siberian cocklebur bighead atractylodes rhizome honey-fried licorice root tangerine peel, pinellia ternate replenishes qi to invigorate the spleen, and only stomach is received vigorous, and the middle strong fortune of soil is normal, make " biochemistry " it Source is inexhaustible, and nutrition is abundant, is just resistant to the injury of cancer evil poison, while is also beneficial to sending an expedition against for eliminating evil medicine.
The Chinese medicine preparation of the present invention can effectively treat liver cancer, and the treatment of brilliance is achieved through clinical practice application for many years Its cure rate is imitated up to more than 90%.Now with the relevant clinical treatment situation of 100 liver cancer, details are as follows:
1st, patient profile:Select the projects such as medical history, the state of an illness, age, sex and original therapy method
2nd, patient source:Out-patient.
3rd, patient's inclusion criteria:Liver cancer is diagnosed as standard to take the photograph piece B ultrasound or biopsy without exception.
4th, method of administration:Take the Chinese medicine preparation of the present invention:Water decoction, 3 times a day, early, middle and late meal previous hour are each Take once and swallow the capsule 3 equipped with medicinal powder every time.With 3 for a course for the treatment of
5th, medication taboo:Chicken, dove, pig's head, pig's feet, beef, mutton, dog meats, fish, shrimp, crab, pungent, peppery etc. and its all hairs The thing that sore is got angry particularly cigarette, drinks, should more wipe out sexual intercourse
6th, efficacy evaluation:
(1) fully recover:Symptom is wholly absent, and takes the photograph piece or ultrasound diagnosis cancerous swelling disappears.
(2) it is effective:Symptom largely disappears, and takes the photograph piece or ultrasound diagnosis cancerous swelling is reduced significantly
(3) effectively:Symptom substantially mitigates, and takes the photograph piece or ultrasound diagnosis cancerous swelling has reduced.
(4) it is invalid:Symptom improves unobvious, takes the photograph piece or ultrasound diagnosis cancerous swelling does not reduce.
6th, efficacy analysis:
(1) sex:By inclusion criteria, 60 (60%) women of male 40 (40%)
(2) course of disease:3-6 months 50.More than 7 months 50.
(3) age:30-40 year 20 41-60 year 50 more than 60 years old 30
(4) curative effect:Cure rate more than 90%, effective percentage 100%
The effect of feeling quite pleased is have received by using the Chinese medicine preparation treatment liver cancer of the present invention.Clinical treatment is entered in outpatient service Capable.
Before the treatment of this group of case, chemotherapy of the most of patients all Jing Guo doctor trained in Western medicine, radiotherapy, intervention, operative treatment, because of curative effect not It is good, and diagnosis and treatment of coming.
It is simultaneously relevant with diet feelings will more than this disease that other drugs must not be taken during taking.As for spirit comfort with Diet is taken good care of oneself, and for partner treatment, raising curative effect is necessary, clinical also very important.
The Chinese medicine preparation of the present invention has selected clearing heat and detoxicating, promoting blood circulation and removing blood stasis, promoting the circulation of qi resolving sputum, softening and resolving hard mass, righting, invigorating the spleen benefit Stomach, anticancer and the medicine for killing cancer cell, after patient uses, without it is any how toxicity, and curative effect is rather notable.Cure rate reaches More than 90%, effective percentage 100%
The therapeutic effect observation for now lifting 2 typical patients is as follows
Case 1:Yang, man, 56 years old, firmly Chongqing City Changshou District Fu Hegaofeng villages, swelled on June 11st, 2004 from Chongqing The discharge of knurl hospital carrys out here diagnosis and treatment, and patient master states:" in Chongqing, tumour hospital is diagnosed as the pancreas metastasis of cancer of liver cancer system through CT scan. The wheat harvesting period of hospitalization 3 is invalid, and the state of an illness aggravates on the contrary, and last hospital can apply without medicine and advise its discharge." show headache, distending pain in the chest and hypochondrium, food Subtract, waist distending pain, gastral cavilty turgor, spiritlessness and weakness, mesh is yellow, and urine is yellow, and pale tongue is purple, middle part yellow and greasy fur, veins string, and patient takes this hair After 3 doses bright of Chinese medicine preparation, the state of an illness has taken a turn for the better, and continues to take 6 months and fully recover.
Case 2:Slowly so-and-so, male, 65 years old, firmly Chongqing City Changshou District Fengcheng City town Feng Yuan roads 6, at the beginning of 3 days April in 2014 Examine, patient master states:" there is hepatitis B medical history, the conscious frequent pain in upper right abdomen hepatic region portion, diet are reduced afterwards, and body is significantly become thin." warp Multiple hospitals CT scan, nuclear magnetic resonance and B ultrasound, the liver power checkings such as Xinan Hospital, Chongqing, new bridge hospital of Third Military Medical University are made a definite diagnosis Right lobe of liver 15.3cmX15.4cmX15.1cm lumps, ACT 110.8AST 234.6ALT 221CCT 607AFP 295 are diagnosed as Liver cancer makees interventional therapy in new bridge hospital of Third Military Medical University, is looked into after having made 3 interventional therapies, and not only right lobe of the liver cancerous swelling does not contract It is small, 3.1cmX2.4cm, 2.7cmX2.4cm cancerous swelling is seen respectively and makees interventional therapy every time all in left liver and outside left liver on the contrary It can't stand, or even words all be could not explain and, because going to a doctor.During first visit, strong 82 beats/min of patient's veins string length, purplish tongue side has Indentation, thick,yellow and greasy fur, it is that liver blood stasis, the stagnation of the circulation of vital energy, phlegm is solidifying, evil poison according to the diagnosis of the case history of doctor trained in Western medicine and arteries and veins ligulate matter symptom to see Lump formation due to accumulation of pathogens, method when open strongly fragrant, promoting the circulation of qi, promoting blood circulation, resolving sputum, the silt that disappears, softening and resolving hard mass, clearing heat and detoxicating, analgesic, anticancer, righting, QI invigorating are good for The Chinese medicine of spleen, patient takes the Chinese medicine preparation of the present invention, after 4 doses, does the 4th interventional therapy and is said when May 1 is to go to a doctor: " take that to do the 4th interventional therapy after your 4 doses of medicines secondary more quite a lot of than first three, can say words and come, illustrate that your Chinese medicine is effective.From I is not going to make interventional therapy for this, just takes your Chinese medicine." take 15 doses bright of Chinese medicine preparation of this law (2 days one) and arrive afterwards The left liver cancer of hospital's ultrasound diagnosis is swollen to disappear, and diet increase, spirit takes a turn for the better, and language is strong, weak mitigation, continues to arrive after taking 2 courses for the treatment of Examination in hospital cancerous swelling disappear, liver function is normal, clinical symptom disappearance and fully recover
(4) embodiment is by bulk drug:Oriental wormwood 30g fries the Fructus Sophorae and (grinds) 10g inular flower 15g marine alga 20g kelp 20g soft-shelled turtles 30g days fourth 20g Rhizoma Sparganii 20g curcuma zedoary 20g oldenlandia diffusas 60g of first (vinegar system) 15g selfheal 60g Chinese violet 30g dandelions Field pennycress 30g edible tulip 6g vomiting nut 4g Chinese blister beetle 0.3g nidus vespae 30g sarcandra 30g air potato 30g semiaquilegia adoxoides 15g oysters 30g root tuber of aromatic turmeric 20g red sage root 20g radix paeoniae rubrathe 20g ground bettle 15g Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 0.04g stringy stonecrop 40g hypericum japonicum 40g dragons Courage grass 12g radix scutellariae 15g radix bupleuri 15g Radix Codonopsis 30g Radix Astragali 30g fruit of glossy privet 30g fruit of Chinese magnoliavine 10g ginseng 20g bighead atractylodes rhizomes 20g Barrenwort 20g Poria cocos 20g tuber of pinellia 20g dried orange peel 20g honey-fried licorice root 15g folium isatidis 20g Sagina subulata 20g Radix Isatidis 30g silver Flower rattan 30g Radix Angelicae Sinensis 18g Ligusticum wallichiis 18g removes from Chinese herbaceous peony 24g:Edible tulip, Chinese blister beetle, vomiting nut.Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) beats powder and loads 18 altogether Outside capsule, remaining medicine is put into ceramic pot, after adding cold water to cover powder immersion thoroughly, capping, after being first fried boiling with high heat, is changed to text Fire, decoction 900ml is taken, filter, produce, for oral, take within 2nd.It is daily take 3 times it is early, middle and late once a dose before meals, every time Swallow the capsule 3 equipped with medicine.

Claims (2)

  1. A kind of 1. Chinese medicine preparation for treating liver cancer, it is characterised in that:Bulk drug grinds 10g, inular flower by oriental wormwood 30g, the stir-fry Fructus Sophorae 15g, marine alga 20g, kelp 20g, turtle shell vinegar 15g, selfheal 60g, Chinese violet 30g, dandelion 30g, day fourth 20g, Rhizoma Sparganii 20g, Curcuma zedoary 20g, oldenlandia diffusa 60g, field pennycress 30g, edible tulip 6g, vomiting nut 4g, Chinese blister beetle 0.3g, nidus vespae 30g, sarcandra 30g, air potato 30g, semiaquilegia adoxoides 15g, oyster 30g, root tuber of aromatic turmeric 20g, red sage root 20g, radix paeoniae rubrathe 20g, ground bettle 15g, the upper punt-pole of snow 0.04g, stringy stonecrop 40g, hypericum japonicum 40g, felwort 12g, radix scutellariae 15g, radix bupleuri 15g, Radix Codonopsis 30g, Radix Astragali 30g, the fruit of glossy privet It is 30g, fruit of Chinese magnoliavine 10g, ginseng 20g, bighead atractylodes rhizome 20g, barrenwort 20g, Poria cocos 20g, tuber of pinellia 20g, dried orange peel 20g, honey-fried licorice root 15g, big Leafiness 20g, Sagina subulata 20g, Radix Isatidis 30g, honeysuckle stem 30g, Radix Angelicae Sinensis 18g, Ligusticum wallichii 18g, root of herbaceous peony 24g compositions.
  2. 2. a kind of Chinese medicine preparation for treating liver cancer according to claim 1, it is characterised in that remove bulk drug:Edible tulip, Chinese blister beetle, vomiting nut, avenge a upper punt-pole and beat altogether outside powder 18 capsules of loading, remaining medicine is put into ceramic pot, adds cold water to cover medicine After the immersion thoroughly of face, capping, after being first fried boiling with high heat, slow fire is changed to, takes decoction 900ml, filtered, produce, for oral, taken within 2nd It is complete.
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