CN104435767A - External application powder for treating lumbar disc herniation and preparation method of external application powder - Google Patents

External application powder for treating lumbar disc herniation and preparation method of external application powder Download PDF

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CN104435767A
CN104435767A CN201410436321.6A CN201410436321A CN104435767A CN 104435767 A CN104435767 A CN 104435767A CN 201410436321 A CN201410436321 A CN 201410436321A CN 104435767 A CN104435767 A CN 104435767A
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salviae miltiorrhizae
ophidia
radix salviae
radix
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刘传法
左秀云
杨波
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
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Abstract

The invention discloses external application powder for treating lumbar disc herniation. The external application powder comprises the following crude drugs in parts by weight: 9-30 parts of artemisia anomala, 6-12 parts of fructus leonuri, 5-9 parts of drynaria rhizome, 10-15 parts of daemonorops draco, 1-5 parts of pseudo-ginseng, 9-15 parts of radices sileris, 4-9 parts of salviae miltiorrhizae, 3-12 parts of akebiaquinata, 10-25 parts of flowers carthami, 4-10 parts of ophidia, 3-9 parts of cutch and 3-9 parts of gastrodia elata. The external application powder disclosed by the invention is based on the principle of treatment on the lumbar disc herniation in the traditional Chinese medicine; the selected Chinese medicinal materials have the efficacies of relaxing the muscles and stimulating the blood circulation, and relieving pain, so that the external application powder is low in cost; the economic burden of a patient after long-term use is not caused; and the external application powder is a relatively ideal medicine for treating lumbar disc herniation.

Description

External pulvis for the treatment of prolapse of lumbar intervertebral disc and preparation method thereof
Technical field
The invention belongs to traditional Chinese medicine field, especially relate to a kind of external pulvis for the treatment of prolapse of lumbar intervertebral disc and preparation method thereof.
Background technology
Prolapse of lumbar intervertebral disc is due to lumbar degenerative disc, Anular disruption, a series of clinical symptoms that Nucleus pulposus stimulates or pressuring neural root, cauda equina nerve show and sign.Be clinical commonly encountered diseases and cause the topmost reason of lumbago and skelalgia.Lumbar intervertebral disc is equivalent to an amphiarthrosis, is made up of, is distributed between lumbar vertebra hyaline cartilage plate, fibrous ring and vertebral pulp.Anular disruption caused by lumbar intervertebral disc degenerative change or wound, vertebral pulp is deviate from from rent, and compressing lumbar vertebra is neural, thus occurs waist lower limb radiated pain.
The vertebral pulp that prolapse of lumbar intervertebral disc is given prominence to terminates in posterior longitudinal ligament front and is called " giving prominence to ", and enters intraspinal through posterior longitudinal ligament, is called " deviating from ".3 types are divided into: 1, rear outside protruding type according to vertebral pulp back step position.The most weak position, the rear of fibrous ring is in intervertebral disc center line both sides, and itself is weak herein, and lack the support of the powerful middle part fiber of posterior longitudinal ligament, be therefore the modal position of prolapse of lumbar intervertebral disc simultaneously.The most common clinically, account for about 80%.2, central protruding type.Refer to that vertebral pulp is given prominence to, under reaching posterior longitudinal ligament by fibrous ring posterior central.Except causing sciatic nerve symptom, also can stimulate or oppress cauda equina nerve, showing as perineal position paralysis and defecation obstacle.3, outstanding in intervertebral foramina.Refer to vertebral pulp to after fibrous ring through rear and posterior longitudinal ligament charge into canalis spinalis, enters in intervertebral foramina, easily fail to pinpoint a disease in diagnosis, but fortunately its incidence rate is low, only about 1%.
The pathological change process of prolapse of lumbar intervertebral disc is broadly divided into three phases: 1, outstanding early stage: vertebral pulp becomes chunky shape thing because of regression and damage, or in cicatrix sample connective tissue, and the fibrous ring of degeneration can the thinning deliquescing or produce crack because of damage repeatedly.This phase, patient can have chronic problem or pain, but "dead" leg pain.Also somebody is former in pathological changes, can cause Nucleus pulposus because of once large violence.2, the outstanding phase: when wound or normal activity make dmm increase, vertebral pulp is given prominence to from fibrous ring weakness or rent.Outthrust stimulates or namely radioactivity leg pain occurs pressuring neural root, or compressing cauda equina nerve generation fecal and urinary functions obstacle.Gerontal patient, can because of intervertebral disc degeneration, whole fibrous ring becomes weak lax, and intervertebral disc can be diffusivity bulging towards periphery.3, outstanding late period: after prolapse of lumbar intervertebral disc, the course of disease is elder comparatively, and various Secondary cases pathological change all can occur for intervertebral disc itself and other proximity structures.
The clinical manifestation of prolapse of lumbar intervertebral disc is: 1, flank pain.Lumbago is the symptom that Most patients occurs at first, incidence rate about 91%.A few patients only has skelalgia and without lumbago, is not that each patient is bound to lumbago occurs thus.Also have some patients first to occur lumbago, occur skelalgia after a period of time, lumbago alleviates voluntarily or disappears simultaneously, carrys out medical Shi Jin main suit's skelalgia.Pain mostly is twinge, often with lower limb numbness, sour swollen sensation.2, lower limb radiating pain.Lumbago and skelalgia is in wound, fatigue and easily show effect after catching cold, and about 2 ~ 3 weeks each time, can alleviate gradually.When showing effect as lain up, pain often alleviates.Be engaged in heavy physical labour and especially repeatedly bend over that lumbago and skelalgia probability occurs is high for activist.The people do not got enough athletic exercise in addition, lower back muscular strength is poor, even if bend over once in a while to lift weight or lumbar strain, also easily brings out lumbago and skelalgia.Any factor that abdominal pressure is increased as cough, firmly defecation, laugh, sneeze, praise weight, chronic cough etc., all easily bring out lumbago and skelalgia, or the lumbago and skelalgia occurred increased the weight of.3, waist limitation of activity.The anterior flexion and rear stretching of patients with lumbar disc herniation lumbar vertebra is movable closely related with the degree of intervertebral disk hernia.As fibrous ring is not broken completely, lumbar vertebra gets anteflexion position, after stretch limited.When reason is that lumbar vertebra is anteflexion, the ligamenta flava between vertebral plate is nervous, and add vertebral canal volume and intervertebral space rear space, the increase of corresponding posterior longitudinal ligament tensity makes the nucleus pulposus portion given prominence to also receive, thus alleviates the symptom of nerve root compression.4, skoliosis.This is patients with lumbar disc herniation is the taked Postural compensatory deformity that eases the pain.Performance is lumbar vertebra to the left or right lateral bending, and the spinous process touching center position at back can find that spinous process is partially askew, but this is not the peculiar sign of prolapse of lumbar intervertebral disc, and the normal person of about 50% also has spinous process partially askew.5, intermittent claudication.The limping that prolapse of lumbar intervertebral disc occurs mostly is intermittent, occurs lower limb pain after a segment distance distance of namely walking, unable, bend over or squat down have a rest after symptom can alleviate, still can walk on.As time goes on, symptom slowly increases the weight of gradually, and it is shorter that the stand up time before there is above-mentioned symptom or travel distance shorten travel distance gradually, and the state of an illness is heavier.6, stolidity.In the patient of prolapse of lumbar intervertebral disc, some there will not be the pain of lower limb, and only occurs the feeling of numbness of limbs, and this majority is because the somesthetic sensibility of disc tissue pressuring nerve and sense of touch fiber cause.Large leg outer side is common numb region, can have burn feeling, stand for a long time and can increase the weight of feeling of numbness when trousers of wearing the clothes contact.Prolapse of lumbar intervertebral disc brings many miseries often to the live and work of patient, even causes deformity, disability.Therefore, find that prolapse of lumbar intervertebral disc just should accomplish timely treatment, external application powder can play blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, anti-inflammatory analgetic effect, and then the object reaching treating both the principal and secondary aspects of a disease.And should strenuous exercise be avoided at treatments period, can not sitting, waist can not be made suddenly stressed.
In the method for existing treatment prolapse of lumbar intervertebral disc, Authorization Notice No. CN 102579635 B (application number 201210041534.X) patent discloses a kind of external medicine composition for the treatment of prolapse of lumbar intervertebral disc, it is characterized in that, its formula and quality proportioning are: Flos Caryophylli, Fructus Gardeniae, Flos Carthami, Rhizoma Drynariae, Radix Angelicae Sinensis, Radix Notoginseng, Radix Et Rhizoma Rhei, Semen Persicae, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong=2: 2: 2: 4: 4: 2: 5: 3: 4: 4.Authorization Notice No. CN 102920954 B (application number 201210498050.8) patent discloses a kind of Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc, it is characterized in that, it is be made up of following raw material: Radix Puerariae 10-30 part, Fructus Chaenomelis 15-30 part, Rhizoma Et Radix Notopterygii 15-30 part, Radix Angelicae Pubescentis 10-20 part, Radix Gentianae Macrophyllae 15-30 part, Sanguis Draxonis 10-20 part, Radix Angelicae Sinensis 10-20 part, Rhizoma Chuanxiong 10-25 part, Radix Clematidis 20-35 part, Radix Paeoniae Alba 10-30 part, Pheretima 15-25 part, Herba Taxilli 20-40 part, Radix Saposhnikoviae 10-20 part, Cortex erythrinae 20-40 part, Semen Coicis 10-30 part, Zaocys 10-20 part and Radix Glycyrrhizae 5-10 part.It is desirable that effect for treatment prolapse of lumbar intervertebral disc is also not so good as powder, and so-called " being medicine three points of poison ", takes medicine in a large number, can cause extra burden to the health of patient.
Summary of the invention
For the present situation of existing treatment prolapse of lumbar intervertebral disc deficiency, an object of the present invention is the external pulvis providing treatment prolapse of lumbar intervertebral disc, has easy absorption, the feature that pain relieving is fast, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned external pulvis.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The external pulvis for the treatment of prolapse of lumbar intervertebral disc, each crude drug is as follows, is weight portion: Herba Artemisiae Anomalae 9-30, Fructus Leonuri 6-12, Rhizoma Drynariae 5-9, Sanguis Draxonis 10-15, Radix Notoginseng 1-5, Radix Saposhnikoviae 9-15, Radix Salviae Miltiorrhizae 4-9, Caulis Akebiae 3-12, Flos Carthami 10-25, ophidia 4-10, catechu 3-9, Rhizoma Gastrodiae 3-9.
The external pulvis for the treatment of prolapse of lumbar intervertebral disc, preferred scheme is, each crude drug is as follows, be weight portion: Herba Artemisiae Anomalae 15-25, Fructus Leonuri 7-10, Rhizoma Drynariae 6-8, Sanguis Draxonis 12-14, Radix Notoginseng 2-4, Radix Saposhnikoviae 10-13, Radix Salviae Miltiorrhizae 5-7, Caulis Akebiae 5-10, Flos Carthami 15-20, ophidia 6-9, catechu 5-8, Rhizoma Gastrodiae 5-7.
The external pulvis for the treatment of prolapse of lumbar intervertebral disc, better preferred scheme is that each crude drug is as follows, is weight portion: Herba Artemisiae Anomalae 20, Fructus Leonuri 8, Rhizoma Drynariae 7, Sanguis Draxonis 13, Radix Notoginseng 3, Radix Saposhnikoviae 11, Radix Salviae Miltiorrhizae 6, Caulis Akebiae 7,18 parts, Flos Carthami, ophidia 8, catechu 6, Rhizoma Gastrodiae 6.
The preparation method of above-mentioned external pulvis, preparation process is as follows:
(1) decaptitated by ophidia, the block being cut into 0.5-1.5cm (preferred 1cm) puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, soak 1-3 days, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fry to sliding sharp state, drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry 1-5 minute fast, takes out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 10-20 hour (preferably 15 hours), and taking-up is placed in low baking temperature on tile and is dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Radix Saposhnikoviae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Rhizoma Gastrodiae add in step (1) gained filtrate, and mixing, after slightly vexed 1-5 hour, decoct with water 2 times, intense fire is fried open for the first time, turns 10-30 minute at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 30-50 minute slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 1-3 slowly, namely cool bottling of drying in the air obtains external pulvis.
The preparation method of foregoing external pulvis, the consumption of step (1) jowar wine is that the 2-6 of the total consumption of ophidia and Radix Salviae Miltiorrhizae is doubly (preferred, the consumption of jowar wine is 3-5 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, more preferably good, the consumption of jowar wine is 4 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae).
The preparation method of foregoing external pulvis, step (1) drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, and stir-fry 2-4 minute fast, (preferably drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 3 minutes).
The preparation method of foregoing external pulvis, the consumption of step (2) white vinegar is Herba Artemisiae Anomalae, Fructus Leonuri, doubly (preferred, the consumption of white vinegar is Herba Artemisiae Anomalae to the 1-5 of Rhizoma Drynariae and Sanguis Draxonis gross weight, Fructus Leonuri, doubly, be more added with choosing, the consumption of white vinegar is Herba Artemisiae Anomalae for the 2-4 of Rhizoma Drynariae and Sanguis Draxonis gross weight, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis gross weight 3 times).
The preparation method of foregoing external pulvis, step (3), after slightly vexed 2-4 hour, decocts with water 2 times, intense fire is fried open for the first time, turns and (preferably after slightly vexed 3 hours, decocts with water 2 times in 15-25 at a simmer minute, intense fire is fried open for the first time, turns 20 minutes at a simmer).
The preparation method of foregoing external pulvis, step (3) low baking temperature that again adds water is decocted 35-45 minute (preferred, the low baking temperature that again adds water decocts 40 minutes slowly) slowly.
The preparation method of foregoing external pulvis, step (4) is placed in low baking temperature on clean tile when drying 1.5-2.5 slowly when on clean tile, low baking temperature dries 2 slowly (preferred, be placed in).
Using method: for making the present invention reach optimum therapeuticing effect, during use, gets Chinese powder medicine 40-60g of the present invention, with Ovum Gallus domesticus album mixing, is applied on adhesive plaster, sticks in lumbar vertebra place, within 1 day, changes once, within 10 days, is a course for the treatment of.
This external pulvis, can not only pain relieving to the Be very effective of prolapse of lumbar intervertebral disc, can also relaxing muscles and tendons to promote blood circulation, QI and blood regulating, improves the body constitution of patient's weakness because of chronic pain, and the local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The external pulvis for the treatment of prolapse of lumbar intervertebral disc, the pharmacological effect of each crude drug is respectively:
Herba Artemisiae Anomalae: have another name called Herba Artemisiae Anomalae grass, Herba Senecionis Scandentis is the wounded in the battle herb of Compositae sagebruss artemisia anomalas.The property of medicine: stem is cylindrical, surperficial brown color or brown-green, matter is hard and crisp, frangibility, the integrated spike panicle of head inflorescence, withered yellow, gas fragrance, bitter in the mouth, pungent, warm in nature.Composition: mainly containing arteanoflavone, tricin, apigenin, Palmic acid etc.Find according to modern pharmacological research, this medical instrument has effect of anti-hypoxia, blood circulation promoting and blood stasis dispelling, removing food stagnancy, hemostasia and detumescence, for amenorrhea due to stagnation of blood, and abdominal pain due to retention of food, hematuria, the diseases such as scald.
Fructus Leonuri: be the fruit of Labiatae mother wort plant Herba Leonuri and Herba Leonuri Sibirici.Composition: leonuri,fructus contains allene class fatty acid containing alkaloid, herb containing phenolic glycoside class, Herba Leonuri Sibirici fruit kind oil.Pharmacology: have hypotensive effect, has the effect of stimulon palace excitement.The property of medicine: sweet, pungent, be slightly cold, mild toxicity, return Liver Channel.Function cures mainly: blood circulation promoting and blood stasis dispelling, liver heat removing and eyesight improving.
Rhizoma Drynariae: nature and flavor: bitter, temperature.Gui Jing: return kidney, Liver Channel.Effect: the kidney invigorating bone strengthening, continues and hinders pain relieving.Cure mainly: for lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.
Sanguis Draxonis: nature and flavor: sweet, salty is flat.Gui Jing: GUIXIN, Liver Channel.Effect: removing blood stasis and relieving pain, hemostasia and promoting granulation.Cure mainly: lose for falling to flutter, ecchymoma due to internal injury; Continuous bleeding due to traumatic injury.
Radix Notoginseng: nature and flavor: sweet, micro-hardship, temperature.Gui Jing: return liver, stomach warp.Effect: dissipating blood stasis stops blooding, subduing swelling and relieving pain.Cure mainly: for spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Radix Saposhnikoviae: nature and flavor: pungent, sweet. temperature.Gui Jing: return bladder, liver, spleen channel.Effect: inducing diaphoresis to dispel wind, victory is wet, relieving convulsion.Cure mainly: for headache due to common cold. rheumatic arthralgia, rubella pruritus, tetanus.
Radix Salviae Miltiorrhizae: nature and flavor: bitter, is slightly cold.Gui Jing: GUIXIN, Liver Channel.Effect: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.Cure mainly: for menoxenia, amenorrhea dysmenorrhea ， lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Caulis Akebiae: nature and flavor: bitter, is slightly cold.Gui Jing: GUIXIN, small intestinal, urinary bladder channel.Effect: clearing away heart-fire, diuresis, stimulating milk secretion of stimulating the menstrual flow.Cure mainly: for irritable feverish sensation in the chest, larynx disease pharyngalgia, dark coloured urine, five types of stranguria, edema, whole body spasm and pain, amenorrhea breast is few.
Flos Carthami: nature and flavor: pungent, temperature.Gui Jing: GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Cure mainly: for amenorrhea, dysmenorrhea, lochia ， mass in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Ophidia: Zaocys, is commonly called as Zaocys, zaocys dhumnades, for Colubridae Zaocys belongs to the larger nonpoisonous snake of the bodily form, sweet, flat.Return Liver Channel.Dispel the wind, dredging collateral, relieving convulsion.For rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Catechu: catechu, another name CATECHU, Catechu, gambier are pulse family albizzia plant catechu tree.Bitter, puckery, be slightly cold.Heat clearing away, promotes the production of body fluid, and reduces phlegm, sore, hemopoietic.For watery diarrhea, endo-enteritis, oral cavity ulceration, eczema, cough, knife injury is hemorrhage.
Rhizoma Gastrodiae: having another name called rhizoma gastrodiae, solely shake sesame, from mother, close from grass, SHENCAO, yellow moccasin flower, Mokpo, RHIZONA GASTRODIAE, DINGFENGCAO, Bai Longpi etc., is the orchid family Gastrodia herbaceos perennial.Nature and flavor: sweet are flat.Endogenous wind stopping, arresting convulsion.Control dizzy pupil, wind syndrome of head is had a headache, numb limbs and tense tendons, hemiplegia, aphasia, pediatric epilepsy scared wind symptom.
External pulvis of the present invention is based on the principle of traditional Chinese medical herbal treatment prolapse of lumbar intervertebral disc.The Chinese medicinal material selected all has relaxing muscles and tendons to promote blood circulation, effect of pain relieving, and cheap, and life-time service also can not cause the financial burden of patient, is to treat the ideal medicine of prolapse of lumbar intervertebral disc.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 treats the external pulvis of prolapse of lumbar intervertebral disc, and each crude drug is as follows, is weight portion (getting 10g for every part): Herba Artemisiae Anomalae 9 parts, Fructus Leonuri 6 parts, Rhizoma Drynariae 5 parts, Sanguis Draxonis 10 parts, Radix Notoginseng 1 part, Radix Saposhnikoviae 9 parts, Radix Salviae Miltiorrhizae 4 parts, Caulis Akebiae 3 parts, 10 parts, Flos Carthami, ophidia 4 parts, 3 parts, catechu, 3 parts, Rhizoma Gastrodiae.
The preparation method of the external pulvis of above-mentioned treatment prolapse of lumbar intervertebral disc, step is:
(1) decaptitated by ophidia, the block being cut into 0.5cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 2 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 1 day, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 1 minute, take out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 10 hours, the consumption of white vinegar is Herba Artemisiae Anomalae, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis gross weight 1 times, takes out and is placed in low baking temperature on tile and is dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Radix Saposhnikoviae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Rhizoma Gastrodiae add in step (1) gained filtrate, and mixing, after slightly vexed 1 hour, decoct with water 2 times, intense fire is fried open for the first time, turns 10 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 30 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 1 slowly, namely cool bottling of drying in the air obtains external pulvis.
Model case one Zou XX, man, 40 years old, Harbin, Heilungkiang personage, peasant, started from 2012, waist breakthrough pain also accompanies right lower extremity radiating pain, originally the symptom of cough is also had time, during stool, pain increases the weight of, right crus of diaphragm has feeling of numbness, difficulty in walking, sleeping at night is poor, go to local clinic to check and say the above-mentioned symptom that its fatigue causes, the medicine of some Conventional pain has been opened to it, and enjoin it to have a good rest, eat the medicine of 3 days, also sleep on time, but symptom has no improvement, so detailed inspection of just having gone large hospital to do, be prolapse of lumbar intervertebral disc on inspection after diagnosing, doctor recommends it to use gained powder of the present invention.
Use embodiment 1 gained external pulvis, use 10 days healths pain relief everywhere, feel there is strength; Use 20 days, the pain disappearance that waist etc. are local, can normally walk; Continue use 2 months malaise symptoms to disappear completely; After use again external pulvis plaster of the present invention to consolidate 1 month, drug withdrawal so far without recurrence.
Embodiment 2 treats the external pulvis of prolapse of lumbar intervertebral disc, and each crude drug is as follows, is weight portion (getting 15g for every part): Herba Artemisiae Anomalae 30 parts, Fructus Leonuri 12 parts, Rhizoma Drynariae 9 parts, Sanguis Draxonis 15 parts, Radix Notoginseng 5 parts, Radix Saposhnikoviae 15 parts, Radix Salviae Miltiorrhizae 9 parts, Caulis Akebiae 12 parts, 25 parts, Flos Carthami, ophidia 10 parts, 9 parts, catechu, 9 parts, Rhizoma Gastrodiae.
The preparation method of the external pulvis of above-mentioned treatment prolapse of lumbar intervertebral disc, step is:
(1) decaptitated by ophidia, the block being cut into 1.5cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 6 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 3 days, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 5 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 20 hours, the consumption of white vinegar is Herba Artemisiae Anomalae, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis gross weight 5 times, take out and are placed in low baking temperature on tile and are dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Radix Saposhnikoviae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Rhizoma Gastrodiae add in step (1) gained filtrate, and mixing, after slightly vexed 5 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 30 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 50 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 3 slowly, namely cool bottling of drying in the air obtains external pulvis.
Embodiment 3 treats the external pulvis of prolapse of lumbar intervertebral disc, and each crude drug is as follows, is weight portion (getting 20g for every part): Herba Artemisiae Anomalae 15 parts, Fructus Leonuri 7 parts, Rhizoma Drynariae 6 parts, Sanguis Draxonis 12 parts, Radix Notoginseng 2 parts, Radix Saposhnikoviae 10 parts, Radix Salviae Miltiorrhizae 5 parts, Caulis Akebiae 5 parts, 15 parts, Flos Carthami, ophidia 6 parts, 5 parts, catechu, 5 parts, Rhizoma Gastrodiae.
The preparation method of the external pulvis of above-mentioned treatment prolapse of lumbar intervertebral disc, step is:
(1) decaptitated by ophidia, the block being cut into 0.8cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 3 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 1.5 days, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 2 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 13 hours, the consumption of white vinegar is Herba Artemisiae Anomalae, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis gross weight 2 times, take out and are placed in low baking temperature on tile and are dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Radix Saposhnikoviae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Rhizoma Gastrodiae add in step (1) gained filtrate, and mixing, after slightly vexed 2 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 13 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 35 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 1.5 slowly, namely cool bottling of drying in the air obtains external pulvis.
Model case two Zhu XX, female, 35 years old, Jinan City, Shandong Province personage.Lumbago, pain of buttock, pain on motion aggravates, and can not turn round, bend over, legs become numb, creep as Formica fusca, limbs are blunt to pain, temperature sensing.Walking disorder, even having occurred the symptom of walking lamely, is prolapse of lumbar intervertebral disc after diagnosing.In the past few years, see hospital of a lot of family, massaging and physiotherapeutical shop, clinic, all do not obtain satisfied therapeutic effect.
Use embodiment 3 gained external pulvis, use 5 days, lumbago, lower limb fiber crops symptom is alleviated to some extent; Use 20 days, walking of can having left the bed, limping symptom disappears substantially; Use 1 first quarter moon, every ill symptoms all disappears, and recovers; Consolidate 15 days, appearance without any side effects during using embodiment 3 gained external pulvis.
Embodiment 4 treats the external pulvis of prolapse of lumbar intervertebral disc, and each crude drug is as follows, is weight portion (getting 25g for every part): Herba Artemisiae Anomalae 25 parts, Fructus Leonuri 10 parts, Rhizoma Drynariae 8 parts, Sanguis Draxonis 14 parts, Radix Notoginseng 4 parts, Radix Saposhnikoviae 13 parts, Radix Salviae Miltiorrhizae 7 parts, Caulis Akebiae 10 parts, 20 parts, Flos Carthami, ophidia 9 parts, 8 parts, catechu, 7 parts, Rhizoma Gastrodiae.
The preparation method of the external pulvis of above-mentioned treatment prolapse of lumbar intervertebral disc, step is:
(1) decaptitated by ophidia, the block being cut into 1.3cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 5 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 2.5 days, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 4 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 18 hours, the consumption of white vinegar is Herba Artemisiae Anomalae, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis gross weight 4 times, take out and are placed in low baking temperature on tile and are dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Radix Saposhnikoviae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Rhizoma Gastrodiae add in step (1) gained filtrate, and mixing, after slightly vexed 4 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 25 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 45 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 2.5 slowly, namely cool bottling of drying in the air obtains external pulvis.
Embodiment 5 treats the external pulvis of prolapse of lumbar intervertebral disc, and each crude drug is as follows, is weight portion (getting 30g for every part): Herba Artemisiae Anomalae 20 parts, Fructus Leonuri 8 parts, Rhizoma Drynariae 7 parts, Sanguis Draxonis 13 parts, Radix Notoginseng 3 parts, Radix Saposhnikoviae 11 parts, Radix Salviae Miltiorrhizae 6 parts, Caulis Akebiae 7 parts, 18 parts, Flos Carthami, ophidia 8 parts, 6 parts, catechu, 6 parts, Rhizoma Gastrodiae.
The preparation method of the external pulvis of above-mentioned treatment prolapse of lumbar intervertebral disc, step is:
(1) decaptitated by ophidia, the block being cut into 1cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 4 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 2 days, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 3 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 15 hours, the consumption of white vinegar is Herba Artemisiae Anomalae, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis gross weight 3 times, take out and are placed in low baking temperature on tile and are dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Radix Saposhnikoviae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Rhizoma Gastrodiae add in step (1) gained filtrate, and mixing, after slightly vexed 3 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 20 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 40 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 2 slowly, namely cool bottling of drying in the air obtains external pulvis.
The clinical practice of the external pulvis of test example 1 embodiment 5 gained treatment prolapse of lumbar intervertebral disc: screen 200 routine patients in 4 hospitals, oldest 60 years old, minimal ages 30 years old, 45 years old mean age.Before test 1 week, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group takes embodiment 5 gained external pulvis, and matched group uses other medicine (diclofenac, waist breath aches the medicine of the conventional therapy prolapse of lumbar intervertebral disc such as capsule).Using method is: using method: for making the present invention reach optimum therapeuticing effect, during use, gets Chinese powder medicine 40-60g of the present invention, with Ovum Gallus domesticus album mixing, is applied on adhesive plaster, sticks in lumbar vertebra place, within 1 day, changes once, within 10 days, is a course for the treatment of.Curative effect situation criterion: effectively: after using this product, malaise symptoms alleviates or partial disappearance; Invalid: after using this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1: use embodiment 5 product prolapse of lumbar intervertebral disc patient treatment outcome
Therapeutic effect: clinical effective 145 examples of experimental group, total effective rate 96.7%, experimental group curative effect is apparently higher than matched group.
Alleviate the external pulvis of prolapse of lumbar intervertebral disc, wherein Herba Artemisiae Anomalae Flos Carthami is combined and is done monarch, and ministerial drug is Fructus Leonuri, Sanguis Draxonis, Radix Saposhnikoviae and ophidia, and remaining is adjuvant drug; Monarch drug carries attending effectiveness in the present invention, effect of all having blood blood stasis dispellings; Ministerial drug is the medicine that auxiliary monarch drug strengthens the main disease for the treatment of and main symptom; Adjuvant drug treatment is held concurrently disease, slows down the strong of monarch drug and ministerial drug; Medicine is made to play a part guiding drug.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat the external pulvis of prolapse of lumbar intervertebral disc, it is characterized in that: each crude drug is as follows, is weight portion: Herba Artemisiae Anomalae 9-30, Fructus Leonuri 6-12, Rhizoma Drynariae 5-9, Sanguis Draxonis 10-15, Radix Notoginseng 1-5, Radix Saposhnikoviae 9-15, Radix Salviae Miltiorrhizae 4-9, Caulis Akebiae 3-12, Flos Carthami 10-25, ophidia 4-10, catechu 3-9, Rhizoma Gastrodiae 3-9.
2. the external pulvis for the treatment of prolapse of lumbar intervertebral disc according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Herba Artemisiae Anomalae 15-25, Fructus Leonuri 7-10, Rhizoma Drynariae 6-8, Sanguis Draxonis 12-14, Radix Notoginseng 2-4, Radix Saposhnikoviae 10-13, Radix Salviae Miltiorrhizae 5-7, Caulis Akebiae 5-10, Flos Carthami 15-20, ophidia 6-9, catechu 5-8, Rhizoma Gastrodiae 5-7.
3. the external pulvis for the treatment of prolapse of lumbar intervertebral disc according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Herba Artemisiae Anomalae 20, Fructus Leonuri 8, Rhizoma Drynariae 7, Sanguis Draxonis 13, Radix Notoginseng 3, Radix Saposhnikoviae 11, Radix Salviae Miltiorrhizae 6, Caulis Akebiae 7,18 parts, Flos Carthami, ophidia 8, catechu 6, Rhizoma Gastrodiae 6.
4. the preparation method of the external pulvis of the treatment prolapse of lumbar intervertebral disc according to claim 1-3, is characterized in that: step is as follows:
(1) decaptitated by ophidia, the block being cut into 0.5-1.5cm (preferred 1cm) puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, soak 1-3 days, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fry to sliding sharp state, drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry 1-5 minute fast, takes out, sieve shakeout, spreading for cooling;
(2) by Herba Artemisiae Anomalae, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis white vinegar soak 10-20 hour (preferably 15 hours), and taking-up is placed in low baking temperature on tile and is dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Radix Saposhnikoviae, Radix Salviae Miltiorrhizae, Caulis Akebiae, Flos Carthami, catechu and Rhizoma Gastrodiae add in step (1) gained filtrate, and mixing, after slightly vexed 1-5 hour, decoct with water 2 times, intense fire is fried open for the first time, turns 10-30 minute at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 30-50 minute slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 1-3 slowly, namely cool bottling of drying in the air obtains external pulvis.
5. the preparation method of external pulvis according to claim 4, it is characterized in that: the consumption of step (1) jowar wine is that the 2-6 of the total consumption of ophidia and Radix Salviae Miltiorrhizae is doubly (preferred, the consumption of jowar wine is 3-5 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, more preferably good, the consumption of jowar wine is 4 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae).
6. the preparation method of external pulvis according to claim 4, it is characterized in that: step (1) drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry 2-4 minute fast, (preferably drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 3 minutes).
7. the preparation method of external pulvis according to claim 4, it is characterized in that: the consumption of step (2) white vinegar is Herba Artemisiae Anomalae, Fructus Leonuri, doubly (preferred, the consumption of white vinegar is Herba Artemisiae Anomalae to the 1-5 of Rhizoma Drynariae and Sanguis Draxonis gross weight, Fructus Leonuri, doubly, be more added with choosing, the consumption of white vinegar is Herba Artemisiae Anomalae for the 2-4 of Rhizoma Drynariae and Sanguis Draxonis gross weight, Fructus Leonuri, Rhizoma Drynariae and Sanguis Draxonis gross weight 3 times).
8. the preparation method of external pulvis according to claim 4, it is characterized in that: step (3) is after slightly vexed 2-4 hour, decoct with water 2 times, intense fire is fried open for the first time, turn 15-25 at a simmer minute (preferably after slightly vexed 3 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 20 minutes at a simmer).
9. the preparation method of external pulvis according to claim 4, is characterized in that: step (3) low baking temperature that again adds water is decocted 35-45 minute (preferred, the low baking temperature that again adds water decocts 40 minutes slowly) slowly.
10. the preparation method of external pulvis according to claim 4, is characterized in that: step (4) is placed in low baking temperature on clean tile when drying 1.5-2.5 slowly when on clean tile, low baking temperature dries 2 slowly (preferred, be placed in).
CN201410436321.6A 2014-08-29 2014-08-29 External application powder for treating lumbar disc herniation and preparation method of external application powder Pending CN104435767A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101485836A (en) * 2008-01-16 2009-07-22 孙玉湘 Oral capsule for treating neck, waist and leg pain diseases and preparation method thereof
CN102240391A (en) * 2011-06-30 2011-11-16 孙立军 Traditional Chinese medicine solution for health promotion
CN103006962A (en) * 2013-01-12 2013-04-03 韩洁 Externally used traditional Chinese medicine liquid for treating osteoproliferation and lumbar disc herniation
CN103316105A (en) * 2013-07-10 2013-09-25 孙云霞 Traditional Chinese medicinal plaster for treating lumbar disc herniation and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101485836A (en) * 2008-01-16 2009-07-22 孙玉湘 Oral capsule for treating neck, waist and leg pain diseases and preparation method thereof
CN102240391A (en) * 2011-06-30 2011-11-16 孙立军 Traditional Chinese medicine solution for health promotion
CN103006962A (en) * 2013-01-12 2013-04-03 韩洁 Externally used traditional Chinese medicine liquid for treating osteoproliferation and lumbar disc herniation
CN103316105A (en) * 2013-07-10 2013-09-25 孙云霞 Traditional Chinese medicinal plaster for treating lumbar disc herniation and preparation method thereof

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