CN104430899A - Hypoallergenic infant formula milk powder and preparation method thereof - Google Patents
Hypoallergenic infant formula milk powder and preparation method thereof Download PDFInfo
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Abstract
The invention discloses hypoallergenic infant formula milk powder and a preparation method of the hypoallergenic infant formula milk powder. The hypoallergenic infant formula milk powder comprises raw milk, part of protein hydrolysate, alpha-lactalbumin, compound fat, lactose, prebiotics, calcium carbonate, decavitamin, composite mineral substances, potassium chloride, magnesium chloride, taurine, choline chloride, unsaturated fatty acid, probiotics and water. The hypoallergenic infant formula milk powder meets the requirement that nutrition needed during healthy growth of an infant is balanced and reasonable and has the hypoallergenic effect, the hypoallergenic infant formula milk powder can be dissolved into uniform liquid at normal temperature, the phenomenon of small particles is avoided during dissolution, and the hypoallergenic infant formula milk powder can be more suitable for industrial production; according to the preparation method, operation is easy and convenient.
Description
Technical field
The present invention relates to field of food, be specifically related to a kind of muting sensitive infant formula and preparation method thereof.
Background technology
0 ~ June is be transitioned into the critical period of living uterus from intrauterine life for baby, this period topmost feature be grow very rapid, need to take in enough energy and nutrition, as do not met, easily cause nutritional deficiency, even impact is grown.But this period, the growth of each organ was not yet ripe, and function does not perfect, to food digest and assimilate and the ability of excrete wastes low, as weak in pepsic vigor, renin and lipase content few, and take in the requirement of high nutrition and produce contradiction, therefore advocate employing breast-feeding.Muting sensitive infant formula can be fed, to meet its demand of growing to breast-fed babies cannot be obtained.But there will be the symptoms such as the bad and allergic reaction of proteopepsis after some muting sensitive infant formula of a part of infants, the incidence of disease is about 2% ~ 6%, seriously affect growing up healthy and sound until adult of infant.Therefore, European PDA and clinical immunology association (ESPACI) and European pediatric gastroenterology, hepatopathy and NI (ESPGHAN) jointly state for excessive risk infant: " within least 4 months, carry out breast-feeding after encouraging baby due.If can not Pure breast feeding, suggestion uses low sensitization formula milk ".Paediatrics association of the U.S. (AAP) also advises: " because obvious family allergies cause the baby that there is high irritated risk, can benefit from Pure breast feeding, low sensitization formula or partial hydrolysis formula milk ".
And it is poor for milk protein enteron aisle tolerance in the market, the prescription emulsifiable powder having the baby of irritated risk to develop usually adopts partially hydrolyzed whey protein as raw material, its target is mainly in the sensitization reducing lactalbumin raw material, it pays close attention to less to the proportioning combination of each nutrient in formula and harmony, products taste often has bitter taste, when reconstituting, dissolution velocity is slow, and occurs small particles phenomenon.
Summary of the invention
Technical problem to be solved by this invention is, overcome muting sensitive infant formula in prior art and be difficult to take into account the proportioning equilibrium of each nutritional labeling in order to reduce sensitization, there is dissolution velocity when reconstituting slow simultaneously, easily there is the defect that small particles and mouthfeel are often bitter, and a kind of muting sensitive infant formula and preparation method thereof is provided, muting sensitive infant formula of the present invention takes into account the balanced of subsensitivety and each nutritional labeling, and dissolution velocity soon, easily reconstitutes without small particles, and taste flavor is pleasant; Preparation method of the present invention is simple and easy to do, is more adapted to suitability for industrialized production.
The present inventor finds in the R&D process of infant formula, and the golden standard of the breast milk that covets easily causes milk powder to part baby sensitization, but in order to reduce sensitization, is then difficult to the overall balance taking into account nutrition.After a large amount of experimental exploring and practical proof repeatedly, inventor finds to carry out meticulously preferably to each raw material of prescription emulsifiable powder, concrete proportioning is more limited to some emphasis components wherein, be aided with special technique again, an aforementioned techniques difficult problem can be solved, obtained infant formula is balanced in nutrition, and muting sensitive, also has excellent brew and excellent mouthfeel.
The invention provides a kind of preparation method of muting sensitive infant formula, the raw material of described muting sensitive infant formula comprises following component, raw milk 57% ~ 62%, partially hydrolysed protein 1.70% ~ 1.87%, alpha lactalbumin 1.6% ~ 2.2%, compound lard 10.9% ~ 13.7%, lactose 20.5% ~ 20.9%, prebiotics 1.66% ~ 2.00%, calcium carbonate 0.11% ~ 0.13%, B B-complex 0.06% ~ 0.075%, composite mineral matter 0.06% ~ 0.075%, potassium chloride 0.22% ~ 0.24%, magnesium chloride 0.09% ~ 0.10%, taurine 0.020% ~ 0.025%, Choline Chloride 0.045% ~ 0.048%, unrighted acid 0.85% ~ 1.84%, probio 0.045% ~ 0.048% and water, described percentage is the mass percent of the gross mass of the raw material accounted for than water, described compound lard contains 15 ~ 16% 1,3 ~ bis-oleic acid 2 ~ palmitic acid three esters, and surplus is the mixed vegetable oil fat of this area routine, and described percentage is the mass percent accounting for compound lard,
Described preparation method comprises the following steps:
(1) raw milk sterilization, obtains the raw milk after sterilization; The pre-molten calcium carbonate of water, composite mineral matter, potassium chloride and magnesium chloride, obtain calcium carbonate molten in advance, composite mineral matter, potassium chloride and magnesium chloride; By a part of lactose and partially hydrolysed protein in (1.5 ~ 2): 1 ratio premix, namely obtains batching 1 with membrane filtration sterilization after dissolving, described ratio is mass ratio;
(2) batching 2 is prepared: remaining lactose and alpha lactalbumin, taurine, B B-complex, Choline Chloride, prebiotics are added in the raw milk after the sterilization of step (1) gained, hydration; Add compound lard, mixing; Then add molten in advance calcium carbonate, composite mineral matter, potassium chloride and the magnesium chloride of step (1) gained, homogeneous, sterilization, obtain batching 2;
(3) concentrate after the batching 1 of blend step (1) gained and the batching 2 of step (2) gained, carry out spraying dry, obtain dry powder A;
(4) by the powder A of the drying of step (3) gained and unrighted acid in (8 ~ 12): the ratio premix of 1 obtains premixing flour A; By the powder A of the drying of step (3) gained and probio in (8 ~ 12): the ratio premix of 1 obtains premixing flour B; Be dry mixed by described premixing flour A and described premixing flour B, obtain final product, described ratio is mass ratio.
Wherein, raw milk of the present invention is the raw milk of this area routine, is preferably fresh milk.Described raw milk is classified according to fat content, is preferably raw milk and/or skimmed milk.In described raw milk, protein >=3.1%, fat >=3.5%, in described skimmed milk, protein >=3.7%, fat≤0.1%, described percentage is mass percent.The content of described raw milk is 57% ~ 62%, is preferably 57.8% ~ 61.8%, is more preferably 57.8% ~ 60.7%, and described percentage is the mass percent accounting for raw material gross mass.
Described partially hydrolysed protein is the partially hydrolysed protein of this area routine, as is known to the person skilled in the art, generally speaking, partially hydrolysed protein is obtained by hydrolyzing lactoalbumins such as protease, wherein reduce beta-lactoglobulin content, muting sensitive albumen can be provided for muting sensitive infant formula.In the present invention, described partially hydrolysed protein is preferably the partially hydrolysed protein that degree of hydrolysis is 4 ~ 15; Be more preferably the partially hydrolysed protein Arla Lacprodan DI-3071 purchased from Arla company.The content of described partially hydrolysed protein is 1.70% ~ 1.87%, is preferably 1.72% ~ 1.86%, is more preferably 1.72% ~ 1.78%, and described percentage is the mass percent accounting for raw material gross mass.
The content of described alpha lactalbumin is 1.6% ~ 2.2%, is preferably 1.69% ~ 2.15%, is more preferably 1.90% ~ 2.15%, and described percentage is the mass percent accounting for raw material gross mass.
Described compound lard contains 15 ~ 16% 1,3 ~ bis-oleic acid 2 ~ palmitic acid three esters (i.e. structured lipid OPO), and surplus is the mixed vegetable oil fat of this area routine; Be preferably the mixed plant grease of 1,3 ~ bis-oleic acid 2 ~ palmitic acid three esters containing 15.6%, described percentage is the mass percent accounting for compound lard.Preferably, described mixed vegetable oil fat be selected from soybean oil, coconut oil, high oleic sunflower oil and Canola Oil one or more; More preferably, described 1,3 ~ bis-oleic acid 2 ~ palmitic acid three esters are the infat OPO structured lipid that leading grease company of Sweden produces.The content of described compound lard is 10.9% ~ 13.7%, is preferably 10.97% ~ 13.6%, is more preferably 11.5% ~ 13.6%, and described percentage is the mass percent accounting for raw material gross mass.
The content of described lactose is 20.5% ~ 20.9%, is preferably 20.58% ~ 20.84%, is more preferably 20.65 ~ 20.8%, and described percentage is the mass percent accounting for raw material gross mass.
Described prebiotics is the prebiotics of this area routine, prebiotics is a kind of dietary supplements, this material by optionally stimulating the growth of the bacterium in a kind of or minority kind bacterium colony with activity thus producing wholesome effect to host, and then improves the health status of host.Preferably, described prebiotics be selected from oligoisomaltose, FOS, galactooligosaccharide, polyfructosan and xylo-oligosaccharide one or more, be more preferably galactooligosaccharide and/or polyfructosan.The content of described prebiotics is 1.66% ~ 2.00%, and preferably, the content of described galactooligosaccharide is 0.34% ~ 0.47%, is more preferably 0.38% ~ 0.47%; Preferably, the content of described polyfructosan is 1.33% ~ 1.53%, is more preferably 1.33% ~ 1.44%, and described percentage is the mass percent accounting for raw material gross mass.
The content of described calcium carbonate is 0.11% ~ 0.13%, is preferably 0.12% ~ 0.13%, and described percentage is the mass percent accounting for raw material gross mass.
The content of described potassium chloride is 0.22% ~ 0.24%, is preferably 0.23% ~ 0.24%, and described percentage is the mass percent accounting for raw material gross mass.
The content of described magnesium chloride is 0.09% ~ 0.10%, is preferably 0.092% ~ 0.095%, and described percentage is the mass percent accounting for raw material gross mass.
Described B B-complex is the B B-complex of this area routine, and described B B-complex is generally by vitamin A, vitamin D, vitamin E, vitamin K
1, Cobastab
1, Cobastab
2, niacinamide, pantothenic acid, Cobastab
6, Cobastab
12, folic acid, composition is composite forms for biotin and vitamin C etc., in infant formula type products, mainly plays the effect of nutrition fortifier.In described B B-complex, the content of each vitamin component meets the respective standard of GB14880-2012, and described muting sensitive infant formula can be made to meet the regulation of GB10765-2010.The content of described B B-complex is 0.06% ~ 0.075%, is preferably 0.068% ~ 0.072%, is more preferably 0.069% ~ 0.072%, and described percentage is the mass percent accounting for raw material gross mass.
Described composite mineral matter is the composite mineral matter of this area routine, generally by ferrous gluconate, manganese sulfate, copper gluconate, zinc sulfate, sodium selenite and KI etc., composition is composite forms for described composite mineral matter, for in infant formula type products, mainly play the effect of fortification.In described composite mineral matter, the content of each mineral component meets the respective standard of GB14880-2012, and described muting sensitive infant formula can be made to meet the regulation of GB10765-2010.The content of described composite mineral matter is 0.06% ~ 0.075%, is preferably 0.068% ~ 0.072%, is more preferably 0.069% ~ 0.072%, and described percentage is the mass percent accounting for raw material gross mass.
The content of described taurine is 0.020% ~ 0.025%, is preferably 0.022% ~ 0.023%, and described percentage is the mass percent accounting for raw material gross mass.
The content of described Choline Chloride is 0.045% ~ 0.048%, is preferably 0.046% ~ 0.047%, and described percentage is the mass percent accounting for raw material gross mass.
Described unrighted acid is the unrighted acid of this area routine, is preferably selected from one or more in linoleic acid, leukotrienes, arachidonic acid and DHA, is more preferably arachidonic acid and/or DHA.The content of described unrighted acid is 0.85% ~ 1.84%, preferably, described arachidonic content is 0.43% ~ 0.55%, be more preferably 0.46% ~ 0.55%, the content of described DHA is 0.42% ~ 0.49%, be more preferably 0.43% ~ 0.44%, described percentage is the mass percent accounting for raw material gross mass.
Described probio is the probio of this area routine, preferably be selected from animal bifidobacteria (Bifidobacterium animalis), bifidobacterium lactis (Bifidobacterium lactis) and Lactobacillus rhamnosus (Lactobacillus rhamnosus) one or more, be more preferably animal bifidobacteria Bifidobacterium animalis Bb-12.As this area is conventional, when preparing milk powder, probio is generally added with the form of probiotic powder.In the present invention, described probio is added with the form of probiotic powder, and the content of described probiotic powder is 0.045% ~ 0.048%, is preferably 0.046% ~ 0.048%, and described percentage is the mass percent accounting for raw material gross mass.The content of the probio in described probiotic powder is the content of this area routine, is preferably containing probio bacterial classification 1 × 10 in every gram of probiotic powder
11cfu ~ 3 × 10
11cfu is more preferably containing probio bacterial classification 3 × 10 in every gram of probiotic powder
10cfu.
Described water is that this area is conventional, described water is used for the pre-molten operation in step (1), with pre-molten described calcium carbonate, composite mineral matter, potassium chloride and magnesium chloride, the use amount of described water is the conventional use amount of required water in pre-molten operation, not special requirement, as long as can make pre-molten calcium carbonate, composite mineral matter, potassium chloride and magnesium chloride reach desirable effect.Also therefore, when calculating the content of each raw material of the present invention, water is not counted gross mass, in the present invention, the content of each raw material is the mass percent of the gross mass of the raw material accounted for than water.
Step (1) is raw milk sterilization, obtains the raw milk after sterilization; The pre-molten calcium carbonate of water, composite mineral matter, potassium chloride and magnesium chloride, obtain calcium carbonate molten in advance, composite mineral matter, potassium chloride and magnesium chloride; By a part of lactose and partially hydrolysed protein in (1.5 ~ 2): the ratio premix of 1, namely obtains batching 1 with membrane filtration sterilization after dissolving, described ratio is mass ratio.Wherein, the temperature of described sterilization is the temperature of this area routine, is preferably 85 ~ 90 DEG C.The time of described sterilization is the time of this area routine, is preferably 15 ~ 30 seconds; Lower the temperature after described sterilization terminates, the temperature of described cooling is the temperature of this area routine, is preferably 30 ~ 35 DEG C, if do not prepared burden immediately to be cooled to 4 DEG C of preservations.Described temperature molten is in advance the temperature of this area routine, is preferably 30 ~ 35 DEG C; Preferably, describedly moltenly in advance also comprise pre-molten calcium phosphate, the content of described calcium phosphate is 0.020% ~ 0.069%, is preferably 0.021% ~ 0.067%, and described percentage is the mass percent accounting for raw material gross mass.The amount of the water of described pre-molten use is this area routine, is not particularly limited, as long as can treat to be beneficial to the even predissolve of each raw material components molten in advance subsequent step and to use.Described membrane filtration sterilization is the membrane filtration sterilization of this area routine, is preferably 1.4 μm of membrane filtration sterilizations.Preferably, a part of lactose of described premix and the ratio of partially hydrolysed protein are 2:1, and described ratio is mass ratio.
Step (2) is: preparation batching 2: remaining lactose and alpha lactalbumin, taurine, B B-complex, Choline Chloride, prebiotics are added in the raw milk after the sterilization of step (1) gained, hydration; Add compound lard, mixing; Then add molten in advance calcium carbonate, composite mineral matter, potassium chloride and the magnesium chloride of step (1) gained, homogeneous, sterilization, obtain batching 2.Wherein, the temperature of described hydration is the temperature of this area routine, is preferably 30 ~ 40 DEG C; The time of described hydration is the time of this area routine, is preferably 15 ~ 20min; The temperature of described mixing is the temperature of this area routine, is preferably 30 ~ 40 DEG C; The time of described mixing is the time of this area routine, is preferably 5 ~ 10min; The temperature of described homogeneous is the temperature of this area routine, is preferably 50 ~ 60 DEG C; The pressure of described homogeneous is the pressure of this area routine, is preferably 18 ~ 20MPa; The temperature of described sterilization is the temperature of this area routine, is preferably 85 ~ 90 DEG C; The time of described sterilization is the time of this area routine, is preferably 15 ~ 30 seconds.
Step (3) is: concentrate after the batching 1 of blend step (1) gained and the batching 2 of step (2) gained, carry out spraying dry, obtain dry powder A.Wherein, concentrating of described simmer down to this area routine, preferably for quadruple effect concentrates, the solid content that described quadruple effect concentrates acquisition is 40 ~ 50%, be more preferably 40 ~ 45%, described percentage is mass percent, and namely solid content accounts for the mass percent of the mixture of batching 1 and batching 2 mixing gained; Described spraying dry is the spraying dry of this area routine, is preferably pressure spray dryer.The feeding temperature of described pressure spray dryer is 60 ~ 65 DEG C, and EAT is 170 ~ 185 DEG C, and temperature of outgoing air is 70 ~ 82 DEG C, and pressure is 230 ~ 300bar.
Step (4) is: by the powder A of the drying of step (3) gained and unrighted acid in (8 ~ 12): the ratio premix of 1 obtains premixing flour A; By the powder A of the drying of step (3) gained and probio in (8 ~ 12): the ratio premix of 1 obtains premixing flour B; Be dry mixed by described premixing flour A and described premixing flour B, obtain final product, described ratio is mass ratio.Wherein, preferably for the powder A of the drying of step (3) gained and unrighted acid are obtained premixing flour A in the ratio premix of 10:1; Preferably for the powder A of the drying of step (3) gained and probio are obtained premixing flour B in the ratio premix of 10:1; Preferably for described premixing flour A and described premixing flour B is carried out being dry mixed in (0.5 ~ 2): the ratio of 1 is dry mixed; More preferably be dry mixed in the ratio of 1:1 for described premixing flour A and described premixing flour B, described ratio is mass ratio.
Preferably, described preparation method also comprises packaging step, and described packaging step can be the conventional packaging step in this area, as adopted composite plastic container, bar shaped dress or iron flask packing and storing.
The present invention also provides a kind of muting sensitive infant formula obtained by described preparation method.
Muting sensitive infant formula of the present invention, meets following content requirement: energy 2066 ~ 2130kJ/100g; Fat 25 ~ 28g/100g, wherein 1,3 ~ bis-oleic acid 2 ~ palmitic acid three ester content 3.2 ~ 4.6g/100g; Be preferably 4.0 ~ 4.6g/100g, wherein alpha lactalbumin 1.8 ~ 2.1g/100g; Carbohydrate 49.3 ~ 51g/100g, wherein polyfructosan 2.8 ~ 3.2g/100g, galactooligosaccharide 270 ~ 420mg/100g; Calcium 320 ~ 350mg/100g; Vitamin D 9 ~ 10.5ug/100g; DHA (DHA) 50 ~ 66mg/100g; Arachidonic acid (ARA) 80 ~ 100mg/100g; Bifidobacterium 3 × 10
7cfu/g; Calcium-phosphorus ratio reaches 2:1, meets the demand of baby.Fragrance nature, has the peculiar fragrance of milk powder.Have good stability, dissolution velocity is fast, and can dissolve formation uniform solution at normal temperature.
α ~ the protein content of whey of muting sensitive infant formula of the present invention reaches 1.8 ~ 2.1g/100g, close with α ~ protein content of whey in breast milk, greatly reduces simultaneously and easily causes irritated beta-lactoglobulin content.1,3 ~ bis-oleic acid 2 ~ palmitic acid three ester contents reach 3.2 ~ 4.6g/100g, optimize fat composition, and make fatty energy supply ratio reach 48 ~ 50%.The calcium-phosphorus ratio of described muting sensitive infant formula is 2:1, and the calcium-phosphorus ratio in breast milk is also 2:1, and this is calcium and the phosphorus optimal proportion at baby's intestinal absorption; In addition, in described muting sensitive infant formula, vitamin D is 9 ~ 10.5ug/100g, and vitamin D can promote the absorption of calcium.And calcium-phosphorus ratio and vitamin D, between (1:1) ~ (1:5), and not to combine by the general calcium-phosphorus ratio of babies ' formula milk powder in the market.Muting sensitive infant formula of the present invention also adds the prebiotics and probio that help intestinal health.Therefore muting sensitive infant formula of the present invention can meet the demand of growing of baby.
The dissolution velocity of muting sensitive infant formula of the present invention is fast, brew is good, only need be complete with regard to solubilized less than the time of 15 seconds under normal temperature, and form homogeneous solution, can not produce " small particles ", therefore edible more convenient, and the dissolution time of general partially hydrolysed protein formula powder needs 30 seconds even more than 1 minute, and easily form " small particles ".
On the basis meeting this area general knowledge, above-mentioned each optimum condition, can be combined, obtain the preferred embodiments of the invention.
Agents useful for same of the present invention and raw material are all commercially.
Positive progressive effect of the present invention is: preparation method of the present invention utilizes special formula Design and raw material to select, and ensure that described muting sensitive infant formula has been taken into account infantile health and grown the requirement of desired nutritional balanced and reasonable and effect of muting sensitive; Described muting sensitive infant formula can form homogeneous solution at normal-temperature dissolution, dissolution velocity only need soon 15 seconds less than time complete with regard to solubilized; And in course of dissolution, no longer there is the phenomenon of " small particles ", be applicable to suitability for industrialized production; Be convenient for carrying and eat; Preparation method of the present invention is easy and simple to handle.
Detailed description of the invention
Mode below by embodiment further illustrates the present invention, but does not therefore limit the present invention among described scope of embodiments.The experimental technique of unreceipted actual conditions in the following example, conventionally and condition, or selects according to catalogue.
In following embodiment, the source of part material is as follows:
Fresh milk: Shanghai Bright Dairy & Food Co., Ltd.'s dairy products two factory, raw material sources are cow's milk.
Compound lard: for containing 1, the mixed plant grease of 3 ~ bis-oleic acid 2 ~ palmitic acid three esters (i.e. structured lipid OPO), except structured lipid OPO, also containing being selected from one or more of soybean oil, coconut oil, high oleic sunflower oil and Canola Oil, wherein 1,3 ~ bis-oleic acid 2 ~ palmitic acid three ester contents are 15.6%, and described percentage is the mass percent accounting for compound lard; Structured lipid OPO is purchased from leading grease company of Sweden, and other plant oil is purchased from grain and oil (Yingkou) Co., Ltd in good.
Lactose: purchased from Tianjin milky way great achievement Import and Export Co., Ltd..
Polyfructosan: purchased from De Biou trade Co., Ltd.
Galactooligosaccharide: purchased from Shanghai Sibei Biological Technology Co., Ltd.
Partially hydrolysed protein powder: purchased from Shanghai Nuoshen Food Trade Co., Ltd..
Alpha lactalbumin powder: purchased from Shanghai Nuoshen Food Trade Co., Ltd..
Baby's B B-complex: food-grade, purchased from Shanghai Li Cheng nutrition product Science and Technology Co., Ltd..
Baby's composite mineral matter: food-grade, purchased from Shanghai Li Cheng nutrition product Science and Technology Co., Ltd..
Choline Chloride, calcium carbonate, potassium chloride, magnesium chloride, calcium phosphate, taurine: be food-grade, purchased from Shanghai Li Cheng nutrition product Science and Technology Co., Ltd..
Arachidonic acid, DHA: purchased from DSM (China) Co., Ltd.
Animal bifidobacteria bacterium powder: Bifidobacterium animalis, Bb-12 are purchased from Ke Hansen (China) Co., Ltd.
Bifidobacterium lactis bacterium powder: purchased from Ke Hansen (China) Co., Ltd.
Vacuum mixer: purchased from Si Bike (Shanghai) FSM Technologies Ltd.
Embodiment 1
1), composition of raw materials
2), preparation method
(1) fresh milk sterilization (85 DEG C, 15s), is cooled to 30 DEG C, obtains the milk after sterilization; 30 DEG C of pre-molten calcium carbonate of water, composite mineral matter, potassium chloride and magnesium chlorides, obtain calcium carbonate molten in advance, composite mineral matter, potassium chloride and magnesium chloride; By a part of lactose and partially hydrolysed protein in 2:1 ratio premix, after dissolving in Vacuum mixer, namely obtain batching 1 with 1.4 μm of membrane filtration sterilizations, described ratio is mass ratio;
(2) batching 2 is prepared: remaining lactose and alpha lactalbumin, taurine, B B-complex, Choline Chloride, polyfructosan are dropped in the milk after the sterilization of step (1) gained together with galactooligosaccharide, 30 DEG C of hydrations 15 minutes; Add compound lard, 35 DEG C mix 5 minutes; Then after molten in advance calcium carbonate, composite mineral matter, potassium chloride and the magnesium chloride that add step (1) gained mix 5 minutes, 60 DEG C, homogeneous under 20MPa, 85 DEG C, 15s sterilization, obtain batching 2;
(3) carry out quadruple effect after mixing the batching 1 of step (1) gained and the batching 2 of step (2) gained to concentrate, obtain 45% solid content, described percentage is the mass percent that solid content accounts for described batching; 60 DEG C are carried out spraying dry, EAT 180 DEG C, temperature of outgoing air 70 DEG C, and pressure 230bar obtains dry powder A;
(4) the powder A of the drying of step (3) gained and unrighted acid (arachidonic acid and DHA) are obtained premixing flour A in the ratio premix of 8:1; The powder A of the drying of step (3) gained and animal bifidobacteria are obtained premixing flour B in the ratio premix of 8:1; Be dry mixed in the ratio of 0.5:1 by described premixing flour A and described premixing flour B, obtain muting sensitive infant formula, described ratio is mass ratio.
(5) the muting sensitive infant formula of step (4) gained is packed by 400g/ bag.
Embodiment 2
1), composition of raw materials
2), preparation method
(1) fresh milk sterilization (90 DEG C, 20s) is cooled to 32 DEG C, obtains the milk after sterilization; 35 DEG C of pre-molten calcium carbonate of water, calcium phosphate, composite mineral matter, potassium chloride and magnesium chlorides, obtain calcium carbonate molten in advance, calcium phosphate, composite mineral matter, potassium chloride and magnesium chloride; By a part of lactose and partially hydrolysed protein in 1.5:1 ratio premix, after dissolving in Vacuum mixer, namely obtain batching 1 with 1.4 μm of membrane filtration sterilizations, described ratio is mass ratio;
(2) batching 2 is prepared: remaining lactose and alpha lactalbumin, taurine, B B-complex, Choline Chloride, polyfructosan are dropped in the milk after the sterilization of step (1) gained together with galactooligosaccharide, 35 DEG C of hydrations 18 minutes; Add compound lard, 40 DEG C mix 10 minutes; Then after molten in advance calcium carbonate, composite mineral matter, potassium chloride and the magnesium chloride that add step (1) gained mix 8 minutes, 55 DEG C, homogeneous under 20MPa, 90 DEG C, 15s sterilization, obtain batching 2;
(3 mix the batching 1 of step (1) gained and the batching 2 of step (2) gained after carry out quadruple effect concentrate, obtain 40% solid content, described percentage is the mass percent that solid content accounts for described batching; 60 DEG C are carried out spraying dry, EAT 185 DEG C, temperature of outgoing air 82 DEG C, and pressure 250bar obtains dry powder A;
(4) the powder A of the drying of step (3) gained and unrighted acid (arachidonic acid and DHA) are obtained premixing flour A in the ratio premix of 10:1; The powder A of the drying of step (3) gained and bifidobacterium lactis are obtained premixing flour B in the ratio premix of 10:1; Be dry mixed in the ratio of 1:1 by described premixing flour A and described premixing flour B, obtain muting sensitive infant formula, described ratio is mass ratio.
(5) the muting sensitive infant formula of step (4) gained is packed by 900g/ tank.
Embodiment 3
1), composition of raw materials
2), preparation method
(1) fresh milk sterilization (85 DEG C, 30s) is cooled to 35 DEG C, obtains the milk after sterilization; 30 DEG C of pre-molten calcium carbonate of water, calcium phosphate, composite mineral matter, potassium chloride and magnesium chlorides, obtain calcium carbonate molten in advance, calcium phosphate, composite mineral matter, potassium chloride and magnesium chloride; By a part of lactose and partially hydrolysed protein in 2:1 ratio premix, after dissolving in Vacuum mixer, namely obtain batching 1 with 1.4 μm of membrane filtration sterilizations, described ratio is mass ratio;
(2) batching 2 is prepared: remaining lactose and alpha lactalbumin, taurine, B B-complex, Choline Chloride, polyfructosan are dropped in the milk after the sterilization of step (1) gained together with galactooligosaccharide, 40 DEG C of hydrations 20 minutes; Add compound lard, 40 DEG C mix 8 minutes; Then after molten in advance calcium carbonate, composite mineral matter, potassium chloride and the magnesium chloride that add step (1) gained mix 10 minutes, 50 DEG C, homogeneous under 18MPa, 87 DEG C, 30s sterilization, obtain batching 2;
(3) carry out quadruple effect after mixing the batching 1 of step (1) gained and the batching 2 of step (2) gained to concentrate, obtain 50% solid content, described percentage is the mass percent that solid content accounts for described batching; 65 DEG C are carried out spraying dry, EAT 170 DEG C, temperature of outgoing air 80 DEG C, and pressure 300bar obtains dry powder A;
(4) the powder A of the drying of step (3) gained and unrighted acid (arachidonic acid and DHA) are obtained premixing flour A in the ratio premix of 12:1; The powder A of the drying of step (3) gained and animal bifidobacteria are obtained premixing flour B in the ratio premix of 12:1; Be dry mixed in the ratio of 2:1 by described premixing flour A and described premixing flour B, obtain muting sensitive infant formula, described ratio is mass ratio.
(5) the muting sensitive infant formula of step (4) gained is packed by 400g/ bag.
Comparative example 1
1), composition of raw materials
Preparation method is all completely the same with embodiment 1 with all the other conditions.
Table 1 calcium-phosphorus ratio testing result
Wherein, the detection method of calcium and phosphorus is respectively according to GB5413.21 and GB5413.22, and calcium-phosphorus ratio obtains by calculating.
From the testing result of table 1, although comparative example 1 fill a prescription in calcium content and embodiment 1 in calcium content indifference, calcium-phosphorus ratio is only 1.2:1, with breast milk calcium-phosphorus ratio 2:1 gap comparatively greatly, be unfavorable for the absorption of calcium and phosphorus.
Comparative example 2
In preparation method's step (1): by a part of lactose and partially hydrolysed protein in the ratio of 2:1, add Vacuum mixer successively respectively, after dissolving, namely obtain batching 1 with 1.4 μm of membrane filtration sterilizations, described ratio is mass ratio.
Composition of raw materials and embodiment 1 completely the same.
The batching 1 that the batching 1 obtain step (1) in embodiment 1 and comparative example 2 obtain is dissolved respectively in the water of abundance, dissolution experiment finds, batching 1 dissolution velocity that comparative example 2 obtains is slow, easy conglomeration in course of dissolution, produce a large amount of white bubbles after stirring, lysate is comparatively muddy; And batching 1 dissolution velocity that embodiment 1 obtains is fast, the lysate of acquisition is homogeneous clean and clear.Composition of raw materials and embodiment 1 completely the same.
Comparative example 3
1) composition of raw materials and embodiment 3 completely the same.
2) preparation method: (1) fresh milk sterilization (85 DEG C, 30s), is cooled to 35 DEG C, obtains the milk after sterilization; 30 DEG C of pre-molten calcium carbonate of water, calcium phosphate, composite mineral matter, potassium chloride and magnesium chlorides, obtain calcium carbonate molten in advance, calcium phosphate, composite mineral matter, potassium chloride and magnesium chloride; By a part of lactose and partially hydrolysed protein in 2:1 ratio premix, namely obtain batching 1 after dissolving in Vacuum mixer, described ratio is mass ratio;
(2) batching 2 is prepared: remaining lactose and alpha lactalbumin, taurine, B B-complex, Choline Chloride, polyfructosan are dropped in the milk after the sterilization of step (1) gained together with galactooligosaccharide, 40 DEG C of hydrations 20 minutes; Add compound lard, 40 DEG C mix 8 minutes; Then, after molten in advance calcium carbonate, composite mineral matter, potassium chloride and the magnesium chloride that add step (1) gained mix 10 minutes, 50 DEG C, homogeneous under 18MPa, obtain batching 2;
(3) latter 87 DEG C of the batching 2 of the batching 1 of step (1) gained and step (2) gained, 30s sterilization is mixed, the solid content that quadruple effect concentrates acquisition is 50%, and described percentage is the mass percent that solid content accounts for described batching; 65 DEG C are carried out spraying dry, EAT 170 DEG C, temperature of outgoing air 80 DEG C, and pressure 300bar obtains dry powder A;
(4) the powder A of the drying of step (3) gained and unrighted acid (arachidonic acid and DHA) are obtained premixing flour A in the ratio premix of 12:1; The powder A of the drying of step (3) gained and animal bifidobacteria are obtained premixing flour B in the ratio premix of 12:1; Be dry mixed in the ratio of 1:1 by described premixing flour A and described premixing flour B, obtain muting sensitive infant formula, described ratio is mass ratio.
(5) the muting sensitive infant formula of step (4) gained is packed by 400g/ bag.
Effect example 1
The muting sensitive infant formula of embodiment 1 ~ 3 and commercially available brand 1 ~ 2 gained is pressed the method detected described in table 2, and record the relevant parameter such as energy, fat in described muting sensitive infant formula respectively, concrete outcome is as shown in table 2:
The Nutrition Examination result of table 2 muting sensitive infant formula
Wherein, "--" of table 2 represents that content is 0.The bibliography of breast milk content is as follows:
[1] Xu Yonghua. breast milk calcium and inquiring into [J] with baby's calcium nutrition relationship. Children in China Health Care, 1999,7 (4): 265-267.
[2] Chang Guifang, Wang Xingguo. China's human milk fat and babies ' formula milk powder grease present Research [J]. Chinese oil, 2010 (4): 1-6.
[3] Liu Yadong, Song Qiu, Zhi Xiao, etc. aliphatic acid composition and distribution [J] in. mare's milk and ripe breast milk triglycerides. food industry science and technology, 2012,33 (18): 171-173.
[4] Liu Cuiping, Su meter Ya, Qi Xiaoyan, etc. China's breast milk Macronutrient advances in analysis [J]. Agriculture of Anhui science, 2013,41 (32): 12610-12613.
[5] Jia Hongxin, Su meter Ya, Chen Wenliang, etc. the progress [J] of breast milk microorganism. food industry science and technology, 2014,35 (4): 350-357.
[6]Shi Y,Sun G,Zhang Z,et al.The chemical composition of human milkfrom Inner Mongolia of China[J].Food Chemistry,2011,127(3):1193-1198.
[7] DRIs (2013 editions) Chinese Soclety of Nutrition writes
The data of table 2 can illustrate, representative brand 1 and brand 2 are all without alpha lactalbumin and 1,3-bis-oleic acid 2-palmitic acid three ester (structured lipid OPO) and Bifidobacterium nutritive index, calcium-phosphorus ratio is also lower, all differ more with the content in breast milk and ratio, fatty energy supply is relatively more on the low side than also, and infant formula of the present invention is closest to the content of breast milk and ratio, balanced in nutritionly more easily to absorb, there is higher nutritive value.
Effect example 2
According to Chinese dairy processing industry industry standard RHB 204-2004 " infant formula sense organ criticism detailed rules and regulations ", carry out sense organ Comprehensive Assessment from the color and luster of milk powder, structural state, brew, flavour and smell four aspects, full marks are 100 points.Have 10 sense organ criticism person compositions, subjective appreciation carried out, shown in result table 3 is shown to embodiment 1 ~ 3, comparative example 1 ~ 3, commercially available brand 1 and commercially available brand 2 babies ' formula milk powder:
The subjective appreciation testing result of table 3 muting sensitive infant formula
As can be seen from Table 3, in embodiment 1 ~ 3, formula milk sample is compared with comparative example 3 and 2 commercially available brand samples, the Analyses Methods for Sensory Evaluation Results of product is better, mark from the flavour of milk powder and smell, brew, structural state, color and luster four aspects, the scoring that gained babies ' formula milk powder of the present invention obtains is higher, and product quality is more stable.
Effect example 3
Embodiment 3 and comparative example 3 are carried out following experiment, and result is as shown in table 4.
The detection method of wetting time: the 100mL distilled water of 55 DEG C puts into 200mL beaker, takes 13.6g muting sensitive infant formula milk to be checked sample, pours muting sensitive infant formula milk sample into beaker rapidly, starts stopwatch simultaneously and starts to clock.Terminate to clock after the muting sensitive infant formula milk on the water surface all sinks, record milk powder sinking time is wetting time.
Small particles: after having inspected " wetting time " of muting sensitive infant formula milk sample, at the uniform velocity stir by the rotation per second speed of two weeks along chamber wall with large size plastic spoon immediately, mixing time is 40 ~ 50 seconds.Then the lysate (2mL) of obtained muting sensitive infant formula milk sample is toppled in black plastic dish and observe small particles situation.
Table 4 wetability and small particles testing result
As shown in Table 4, compared with embodiment 3, comparative example 3 wetting time is long, occurs that small particles number is many, illustrates that its dissolution velocity is slow, dissolves not easily complete.
Effect example 4
Embodiment 1 and comparative example 3 are carried out following experiment, and result is as shown in table 5.
Table 5 microorganism detection result
Table 5 illustrates, pasteurization in comparative example 3 is the sterilizing methods of this area routine, but but embodiment 1 utilizes membrane filtration bactericidal assay to operate more easyly still can be reached the sterilization effect identical with comparative example 3 and meet the requirement of GB 10765 ~ 2010.
The foregoing is only preferred embodiment of the present invention, do not form the restriction to right, other equivalent in fact substituting, all in scope that those skilled in that art can expect.
Claims (10)
1. the preparation method of a muting sensitive infant formula, the raw material of described muting sensitive infant formula comprises following component, raw milk 57% ~ 62%, partially hydrolysed protein 1.70% ~ 1.87%, alpha lactalbumin 1.6% ~ 2.2%, compound lard 10.9% ~ 13.7%, lactose 20.5% ~ 20.9%, prebiotics 1.66% ~ 2.00%, calcium carbonate 0.11% ~ 0.13%, B B-complex 0.06% ~ 0.075%, composite mineral matter 0.06% ~ 0.075%, potassium chloride 0.22% ~ 0.24%, magnesium chloride 0.09% ~ 0.10%, taurine 0.020% ~ 0.025%, Choline Chloride 0.045% ~ 0.048%, unrighted acid 0.85% ~ 1.84%, probio 0.045% ~ 0.048% and water, described percentage is the mass percent accounting for water-free raw material gross mass, described compound lard contains 15 ~ 16% 1,3 ~ bis-oleic acid 2 ~ palmitic acid three esters, and surplus is the mixed vegetable oil fat of this area routine, and described percentage is the mass percent accounting for compound lard,
Described preparation method comprises the following steps:
(1) raw milk sterilization, obtains the raw milk after sterilization; The pre-molten calcium carbonate of water, composite mineral matter, potassium chloride and magnesium chloride, obtain calcium carbonate molten in advance, composite mineral matter, potassium chloride and magnesium chloride; By a part of lactose and partially hydrolysed protein in (2 ~ 1.5): 1 ratio premix, namely obtains batching 1 with membrane filtration sterilization after dissolving, described ratio is mass ratio;
(2) batching 2 is prepared: remaining lactose and alpha lactalbumin, taurine, B B-complex, Choline Chloride, prebiotics are added in the raw milk after the sterilization of step (1) gained, hydration; Add compound lard, mixing; Then add molten in advance calcium carbonate, composite mineral matter, potassium chloride and the magnesium chloride of step (1) gained, homogeneous, sterilization, obtain batching 2;
(3) concentrate after the batching 1 of blend step (1) gained and the batching 2 of step (2) gained, carry out spraying dry, obtain dry powder A;
(4) by the powder A of the drying of step (3) gained and unrighted acid in (8 ~ 12): the ratio premix of 1 obtains premixing flour A; By the powder A of the drying of step (3) gained and probio in (8 ~ 12): the ratio premix of 1 obtains premixing flour B; Be dry mixed by described premixing flour A and described premixing flour B, obtain final product, described ratio is mass ratio.
2. preparation method as claimed in claim 1, it is characterized in that, described raw milk is fresh milk; The content of described raw milk is 57.8% ~ 61.8%, is preferably 57.8% ~ 60.7%; The degree of hydrolysis of described partially hydrolysed protein is 4 ~ 15; Be preferably the Arla LacprodanDI-3071 purchased from Arla company; The content of described partially hydrolysed protein is 1.72% ~ 1.86%; Be preferably 1.72% ~ 1.78%; The content of described alpha lactalbumin is 1.69% ~ 2.15%; Be preferably 1.90% ~ 2.15%; And/or the content of described lactose is 20.58% ~ 20.84%; Be preferably 20.65 ~ 20.8%, described percentage is the mass percent accounting for raw material gross mass.
3. preparation method as claimed in claim 1, it is characterized in that, described compound lard contains 15.6% 1, the mixed plant grease of 3 ~ bis-oleic acid 2 ~ palmitic acid three esters, and described percentage is the mass percent accounting for compound lard; Described mixed vegetable oil fat be selected from soybean oil, coconut oil, high oleic sunflower oil and Canola Oil one or more; The content of described compound lard is 10.97% ~ 13.6%; Be preferably 11.5% ~ 13.6%; Described prebiotics be selected from oligoisomaltose, FOS, galactooligosaccharide, polyfructosan and xylo-oligosaccharide one or more; Be preferably galactooligosaccharide and/or polyfructosan; The content of described galactooligosaccharide is 0.34% ~ 0.47%; Be preferably 0.38% ~ 0.47%; And/or the content of described polyfructosan is 1.33% ~ 1.53%; Be preferably 1.33% ~ 1.44%, described percentage is the mass percent accounting for raw material gross mass.
4. preparation method as claimed in claim 1, it is characterized in that, the content of described calcium carbonate is 0.12% ~ 0.13%; The content of described potassium chloride is 0.23% ~ 0.24%; The content of described magnesium chloride is 0.092% ~ 0.095%; In described B B-complex, the content of each vitamin component meets the respective standard of GB14880-2012; The content of described B B-complex is 0.068% ~ 0.072%; Be preferably 0.069% ~ 0.072%; In described composite mineral matter, the content of each mineral component meets the respective standard of GB14880-2012; And/or the content of described composite mineral matter is 0.068% ~ 0.072%; Be preferably 0.069% ~ 0.072%, described percentage is the mass percent accounting for raw material gross mass.
5. preparation method as claimed in claim 1, it is characterized in that, the content of described taurine is 0.022% ~ 0.023%; The content of described Choline Chloride is 0.046% ~ 0.047%; Described unrighted acid be selected from linoleic acid, leukotrienes, arachidonic acid and DHA one or more, be more preferably arachidonic acid and/or DHA; Described arachidonic content is 0.43% ~ 0.55%; Be preferably 0.46% ~ 0.55%; The content of described DHA is 0.42% ~ 0.49%; Be preferably 0.43% ~ 0.44%; One or more for being selected from animal bifidobacteria (Bifidobacterium animalis), bifidobacterium lactis (Bifidobacterium lactis) and Lactobacillus rhamnosus (Lactobacillus rhamnosus) of described probio; Be preferably animal bifidobacteria Bifidobacterium animalis Bb-12; Described probio is added with the form of probiotic powder, and the content of described probiotic powder is 0.046% ~ 0.048%, and described percentage is the mass percent accounting for raw material gross mass; And/or the content of the probio in described probiotic powder is containing probio bacterial classification 1 × 10 in every gram of probiotic powder
11cfu ~ 3 × 10
11cfu; Be preferably containing probio bacterial classification 3 × 10 in every gram of probiotic powder
10cfu.
6. preparation method as claimed in claim 1, it is characterized in that, in step (1), the temperature of described sterilization is 85 ~ 90 DEG C; The time of described sterilization is 15 ~ 30 seconds; The temperature of described cooling is 30 ~ 35 DEG C; Described temperature molten is in advance 30 ~ 35 DEG C; Describedly moltenly in advance also comprise calcium phosphate, the content of described calcium phosphate is 0.020% ~ 0.069%, is preferably 0.021% ~ 0.067%, and described percentage is the mass percent accounting for raw material gross mass; Described membrane filtration sterilization is 1.4 μm of membrane filtration sterilizations; And/or a part of lactose of described premix and partially hydrolysed protein ratio are 2:1, described ratio is mass ratio.
7. preparation method as claimed in claim 1, it is characterized in that, in step (2), the temperature of described hydration is 30 ~ 40 DEG C; The time of described hydration is 15 ~ 20min; The temperature of described mixing is 30 ~ 40 DEG C; The time of described mixing is 5 ~ 10min; The temperature of described homogeneous is 50 ~ 60 DEG C; The pressure of described homogeneous is 18 ~ 20MPa; The temperature of described sterilization is 85 ~ 90 DEG C; And/or the time of described sterilization is 15 ~ 30 seconds.
8. preparation method as claimed in claim 1, it is characterized in that, in step (3), described simmer down to quadruple effect concentrates, and the solid content that described quadruple effect concentrates acquisition is 40 ~ 50%, is more preferably 40 ~ 45%, and described percentage is mass percent; Described spraying dry is pressure spray dryer; The feeding temperature of described pressure spray dryer is 60 ~ 65 DEG C; EAT is 170 ~ 185 DEG C; Temperature of outgoing air is 70 ~ 82 DEG C; And/or pressure is 230 ~ 300bar.
9. preparation method as claimed in claim 1, is characterized in that, in step (4), the powder A of the drying of step (3) gained and unrighted acid are obtained premixing flour A in the ratio premix of 10:1; And/or, the powder A of the drying of step (3) gained and probio are obtained premixing flour B in the ratio premix of 10:1; Described premixing flour A and described premixing flour B carries out being dry mixed in (0.5 ~ 2): the ratio of 1 is dry mixed; And/or be preferably dry mixed in the ratio of 1:1 for described premixing flour A and described premixing flour B, described ratio is mass ratio.
10. the muting sensitive infant formula obtained by the preparation method described in claim 1 ~ 9 any one.
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| CN106720347A (en) * | 2016-11-15 | 2017-05-31 | 光明乳业股份有限公司 | A kind of neonate's prescription emulsifiable powder containing probiotics and preparation method thereof |
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