CN106172794A - A kind of baby formula milk powder product for regulating intestinal canal function - Google Patents

A kind of baby formula milk powder product for regulating intestinal canal function Download PDF

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Publication number
CN106172794A
CN106172794A CN201510219569.1A CN201510219569A CN106172794A CN 106172794 A CN106172794 A CN 106172794A CN 201510219569 A CN201510219569 A CN 201510219569A CN 106172794 A CN106172794 A CN 106172794A
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China
Prior art keywords
milk powder
powder product
milk
gos
fos
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CN201510219569.1A
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Chinese (zh)
Inventor
于伟
杨天才
吴登国
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Kai Fu Zi (shanghai) Industrial Co Ltd
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Kai Fu Zi (shanghai) Industrial Co Ltd
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Priority to CN201510219569.1A priority Critical patent/CN106172794A/en
Publication of CN106172794A publication Critical patent/CN106172794A/en
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Abstract

The invention discloses a kind of formula milk product for regulating infant function of intestinal canal, specifically, this milk powder product contains the active component of following weight portion: milk 150-450, Vegetable oil lipoprotein 15-50, prebiotics 1-12, and, being also added with profitable probliotics, its addition is 105CFU/g-1010CFU/g, described addition (CFU/g) is the amount of the probiotic bacteria added in every gram of milk powder product.The formula milk product of the present invention can improve the diarrhoea that infant antibiotic causes.

Description

A kind of baby formula milk powder product for regulating intestinal canal function
Technical field
The present invention relates to a kind of function milk powder, in particular it relates to a kind of infant for regulating intestinal canal function Formula milk product.
Background technology
Infant (0-3 year) is the period that baby grows most critical.Generally, the nutrition in this stage and nursing Mode is extremely important, needs substantial amounts of nutrient substance support, and nutrient substance digest and assimilate all rely on strong The function of intestinal canal of health, and, intestinal, in addition to administering digestion, absorption, secretory function, is also born quite Completing greatly the important task of the human immunity matter of fundamental importance, therefore, intestinal such as He Jiankang, benefited is not only intestinal, more can Benefit whole body.
But, for without breastfeeding baby, owing to lacking distinctive beneficially baby intestinal in breast milk Prebiotics and probiotic bacteria, therefore, without the more breastfeeding baby of breastfeeding baby be more easy to occur constipation, Get angry phenomenon.
Therefore, this area is in the urgent need to developing a kind of baby formula milk powder product for regulating intestinal canal function.
Summary of the invention
It is an object of the invention to provide a kind of baby formula milk powder product for regulating intestinal canal function.
A first aspect of the present invention provides a kind of baby formula milk powder product for regulating intestinal canal function, institute State milk powder product and contain the active component of following weight portion:
Milk 150-450
Vegetable oil lipoprotein 15-50
Prebiotics 1-12
Further, being also added with profitable probliotics, its addition is 105CFU/g-1010CFU/g, described addition (CFU/g) The amount of the probiotic bacteria for adding in every gram of milk powder product;
Wherein, described milk is 150-450:1-12:15-50 with prebiotics, the mass ratio of described Vegetable oil lipoprotein, It is preferred that 200-300:2-8:25-35, more preferably, 250:5:30;Vegetable oil lipoprotein+prebiotics+probiotic bacteria Weight account for the 2-30% of described milk powder product gross weight, it is preferred that 16-24%, more preferably 18-20%; And the weight portion of described milk and described milk are all former with milk with the mass ratio of prebiotics, described Vegetable oil lipoprotein The weight in wet base meter of material.
In another preference, in described milk powder product, water content is less than 5%, preferably 3%, more preferably, 1%.
In another preference, described Vegetable oil lipoprotein accounts for the 15-50% of described milk powder product gross weight, it is preferred that 20-50%, more preferably, 20-45%.
In another preference, described prebiotics accounts for the 1-10% of described milk powder product gross weight, it is preferred that 2-9%, More preferably, 4-8%.
In another preference, described probiotic bacteria accounts for the 0.05-5% of described milk powder product gross weight, it is preferred that 0.1-2%, more preferably, 0.2-1%.
In another preference, described milk is skim milk.
In another preference, the source of described milk is selected from lower group: cattle, sheep or a combination thereof.
In another preference, the addition of described prebiotics is 2-8g, it is preferred that 4-8g, more preferably, 5.5g.
In another preference, described prebiotics be selected from lower group: oligofructose (FOS), oligomeric galactose (GOS), Oligomeric xylose (XOS), oligomeric lactulose (LACT), soybean oligo saccharide (SOS), inulin (Inulin) or a combination thereof.
In another preference, described prebiotics is oligofructose (FOS) and oligomeric galactose (GOS).
In another preference, the mass ratio of described oligofructose (FOS) and oligomeric galactose (GOS) is 1-50: 0.1-5, it is preferred that 10-30:0.5-2, more preferably, 10:1.
In another preference, described Vegetable oil lipoprotein addition is 18-48g, it is preferred that 20-45g.
In another preference, described Vegetable oil lipoprotein is selected from lower group: Oleum Helianthi, Semen Maydis oil, soybean oil, core Fructus Persicae oil, Oleum Arachidis hypogaeae semen, OPO (OPO) or a combination thereof.
In another preference, described Vegetable oil lipoprotein is OPO (OPO).
In another preference, the addition of described probiotic bacteria is 106CFU/g-108CFU/g, it is preferred that 107CFU/g。
In another preference, described probiotic bacteria be selected from lower group: lactic acid bacteria, bacillus bifidus, bacillus acidophilus, Or a combination thereof.
In another preference, described probiotic bacteria is bacillus bifidus BB12
In another preference, described milk powder product contains the active component of following weight portion:
Wherein, described oligofructose (FOS) is 1-50:0.1-5 with the mass ratio of described oligomeric galactose (GOS); Described milk, oligofructose (FOS), oligomeric galactose (GOS) and described 1,3-bis-oleic acid 2-Palmic acid is sweet The mass ratio of oil three esters (OPO) is 150-450:0.8-8:0.2-2:4-12.
In another preference, described milk powder product contains the active component of following weight portion:
Wherein, described oligofructose (FOS) is 10-30:0.5-2 with the mass ratio of described oligomeric galactose (GOS); Described milk powder, oligofructose (FOS), oligomeric galactose (GOS) and described 1,3-bis-oleic acid 2-Palmic acid is sweet The mass ratio of oil three esters (OPO) is 200-400:1.5-7:0.4-1:5-10.
In another preference, described milk powder product contains the active component of following weight portion:
Wherein, described oligofructose (FOS) is 10:1 with the mass ratio of described oligomeric galactose (GOS);Institute State milk, oligofructose (FOS), oligomeric galactose (GOS) and described 1,3-bis-oleic acid 2-palmitic acid The mass ratio of three esters (OPO) is 250:5:0.5:9.
Second aspect present invention provides a kind of baby formula milk powder product for regulating intestinal canal, described milk powder Product contains the active component of following weight portion:
Wherein, described oligofructose (FOS) is 1-50:0.1-5 with the mass ratio of described oligomeric galactose (GOS); Described milk powder, oligofructose (FOS), oligomeric galactose (GOS) and described 1,3-bis-oleic acid 2-Palmic acid is sweet The mass ratio of oil three esters (OPO) is 150-450:0.8-8:0.2-2:4-12.
In another preference, described milk powder product contains the active component of following weight portion:
Wherein, described oligofructose (FOS) is 10-30:0.5-2 with the mass ratio of described oligomeric galactose (GOS); Described milk powder, oligofructose (FOS), oligomeric galactose (GOS) and described 1,3-bis-oleic acid 2-Palmic acid is sweet The mass ratio of oil three esters is 200-400:1.5-7:0.4-1:5-10.
In another preference, described milk powder product contains the active component of following weight portion:
Wherein, described oligofructose (FOS) is 10:1 with the mass ratio of described oligomeric galactose (GOS);Described milk Powder, oligofructose (FOS), oligomeric galactose (GOS) and described OPO (OPO) mass ratio is 250:5:0.5:9.
In another preference, described milk powder product contains the concrete component of following weight portion:
Skim milk 200~350
Lactose 10~35
Vegetable oil 20~45
Concentrated lactoalbumin 10~20
Vitamin 0.5~5
Mineral 0.8~6
Fos+Gos 4~8
OPO 5~10
BB12 0.2~1
Nucleotide 0.05~1
DHA 0.02~0.5
ARA 0.02~0.8
Taurine 0.01~0.5
L-carnitine 0.001~0.1
Third aspect present invention provides the purposes of milk powder product described in a kind of first aspect present invention, second aspect, Described milk powder product alleviates, for non-therapeutic, the diarrhoea that antibiotic causes.
In another preference, described antibiotic is selected from: cephalosporins, Penicillin antibiotics or its Combination.
In another preference, described milk powder product can be also used for (i) balance intestinal flora;(ii) improve Infant constipation;(iii) side effect that vitamin causes is alleviated.
Fourth aspect present invention provides the preparation of milk powder product described in a kind of first aspect present invention, second aspect Method, comprises the following steps:
The inspection of (a) starting milk, clean breast, advance heat-sterilization, defat;
B () mixing FOS, GOS, obtain prebiotics mixed liquor;
C above-mentioned mixed liquor is mixed by () with other nutrients, form liquid phase A;
D OPO is mixed by () with remaining oils and fats, form oil phase B;
E the oil phase B of liquid phase A of step (c) and step (d) is added in skimmed milk by (), homogenizing, cold But;
F () adds vitamin, mineral in step (e), carry out multiple-effect evaporation;
(g) homogenizing, it is spray-dried, cools down;
H () adds bacillus bifidus BB12Lyophilized powder, obtains described milk powder product.
In another preference, described step is carried out by the order of (a)-(h).
In another preference, described Vegetable oil lipoprotein is selected from lower group: Oleum Helianthi, Semen Maydis oil, soybean oil, core Fructus Persicae oil, Oleum Arachidis hypogaeae semen or a combination thereof.
In another preference, other nutrients described are selected from lower group: protide, carbohydrate or a combination thereof.
In should be understood that within the scope of the present invention, above-mentioned each technical characteristic of the present invention and below (as implemented Example) in can be combined with each other between each technical characteristic of specifically describing, thus constitute new or preferred skill Art scheme.As space is limited, the most tired at this state.
Accompanying drawing explanation
Fig. 1 shows the improvement effect of the diarrhoea that antibiotic side effect causes by the milk powder of embodiment 1 component proportion Really.
Fig. 2 shows the impact that baby intestinal flora is balanced by the milk powder of embodiment 1 component proportion.
Fig. 3 shows the milk powder improvement effect to infant constipation of embodiment 1 component proportion.
Detailed description of the invention
The present inventor, through in-depth study for a long time, unexpectedly designs and have developed a kind of energy active balance baby Child's intestinal microbial population, regulation infant function of intestinal canal baby formula milk powder product, this milk powder product by with Lower active component is constituted: milk powder, OPO, FOS, GOS and bacillus bifidus BB12.By FOS, GOS and/ Or OPO and BB12Between carry out proportioning with certain proportion, it is possible to significantly improve what antibiotic side effect brought Diarrhoea.The milk powder product of the present invention can also improve the bowel problems such as infant constipation, flora is unbalance, and Clinical trial shows that this is not only a science but also effective formula.
Active component
As used herein, term " active component " refers to add the necessary change as active component in milk powder Learn material, i.e. Vegetable oil lipoprotein (such as OPO (OPO)), probiotic bacteria (such as Bifidobacterium BB12), prebiotics (such as oligofructose (FOS) and oligomeric galactose (GOS)).
The research of the present invention shows, uses the active component of specific active component and specific proportioning to have The regulation infant function of intestinal canal of effect, improves the side effect that the diarrhoea of infant, constipation and antibiotic cause Etc. problem.Specifically, in the present invention, to account for milk powder product total for the weight of Vegetable oil lipoprotein+prebiotics+probiotic bacteria The 2-30% of weight, it is preferred that 16-24%, more preferably 18-20%, and milk and described oligofructose (FOS), the mass ratio of described oligomeric galactose (GOS) be 150-450:0.8-8:0.2-2, preferably Ground, 200-350:1.5-7:0.5-1, more preferably, 250:5:0.5;Add oligofructose (FOS), Oligomeric galactose (GOS) with the mass ratio of described OPO (OPO) is 0.8-8:0.2-2:1-18, it is preferred that 1.5-7:0.4-1:4-12;More preferably, 100:10:90; Bacillus bifidus BB in every gram of milk powder12Addition be 105CFU/g-1010CFU/g, it is preferred that 106CFU/g -108CFU/g, more preferably, 107CFU/g。
OPO
As used herein, term " OPO " is also called " breast milkization knot Structure fat ", it is called for short OPO.Human milk fat contains a series of fatty acid, the most most is oleic acid (C18: 1) and Palmic acid (C16:0), the 40% and 24% of total fatty acids is accounted for the most respectively.Master in the milk of people The triglyceride wanted is OPO (OPO).
By enzyme process Ester exchange technical modelling breast milk lipid molecular structure, 2 palmitate ratio are made to be up to 40% Above, closer to breast milk level.In breast milk, major part energy exists with fat form, fat in breast milk The Palmic acid of up to 70% is connected on 2, and unsaturated fatty acid is mainly connected on 1,3, i.e. O-P-O Structure, this structural fatty, after digesting and assimilating, preferentially discharge the unsaturated lipid on 1,3 Fat acid is easy to be entered in blood by intestinal absorption, and the Palmic acid on 2 is also easy to be absorbed by intestinal.
The present invention adds " OPO " in baby milk powder, has as follows Effect: (i) effectively reduces the probability producing calcium soap, thus softens baby the most just, reduces baby's intestinal The occurrence probability of obstructed even constipation, it is to avoid baby gets angry;(ii) baby it is effectively increased for energy The absorption of the mineral such as amount and calcium and utilization, reduce nutrient loss;(iii) calcium soap shape is effectively reduced Become, do not affect the absorption of calcium, make calcium fully precipitate in skeleton, thus more preferably support baby's physique and skeleton Naturally grow up.
Generally, OPO addition in baby milk powder is 4-5g, and in the present invention, OPO is at infant Addition in milk powder is 1-18g, it is preferred that 2-10g, more preferably, 9g.
Prebiotics
As used herein, term " prebiotics " includes but not limited to: oligofructose (FOS), oligomeric galactose (GOS), oligomeric xylose (XOS), oligomeric lactulose (LACT), soybean oligo saccharide (SOS), inulin (Inulin), Or a combination thereof.Prebiotics, by regulating internal microecological environment, as reduced intestinal pH value, strengthens beneficial bacteria of intestinal tract Function, play alleviate constipation, recover intestinal bacteria balance, reduce rectal cancer sickness rate, improve baby's intestinal Effect of bacterium colony.
The present invention adds oligofructose (FOS) and oligomeric galactose (GOS) two in baby milk powder by a certain percentage Plant prebiotics.Wherein, FOS have activation intestinal in bacillus bifidus, promote they growth and breedings, simultaneously The effect of suppression pathogenic bacterium;GOS has the effect of the anti-immunity that treats constipation, improves.
In the present invention, the described oligofructose (FOS) of interpolation and the matter of described oligomeric galactose (GOS) Amount ratio is 1-50:0.1-5, it is preferred that 10-30:0.5-2, more preferably, 10:1.
Probiotic bacteria
As used herein, term " probiotic bacteria " refers to the active microorganism that a class is useful to host, is to be colonizated in human body In intestinal, reproductive system, definite health efficacy can be produced thus improve host's microecological balance, play beneficial effect Active beneficial microorganism general name." probiotic bacteria " includes but not limited to: lactobacillus class (as bacillus acidophilus, Lactobacillus casei, Lactobacillus Jensenii, Raman lactobacillus), bacillus bifidus class is (such as bifidobacterium longum, short bifid bar Bacterium, avette bacillus bifidus, bifidobacterium thermophilum), gram-positive cocci (as streptococcus faecalis, Lactococcus, in Jie streptococcus).
The present invention adds bacillus bifidus in baby milk powder, and it is present in breast-fed babies' intestinal in a large number In, infant there are many benefits, such as nutrition, immunity and anti-infectious function, and also there is antiallergic, resist and swell Tumor, adjust function of intestinal canal and improve the effect of nutrition.Specifically, the present invention adds bifid bar in baby milk powder Bacterium BB12, Bifidobacterium BB12 the most also has following function: (i) is high by gastrointestinal tract survival rate; (ii) side effect (such as antibiotic-associated diarrhea) of antibiotic therapy is reduced;(iii) body is improved to often See the resistance of respiratory tract infection, reduce the sickness rate of acute respiratory infection simultaneously;And also there is fabulous acid Bile tolerance and the strongest adhesiveness.
Generally, probiotic bacteria addition in baby milk powder is 106CFU/g, in the present invention, bifid bar Bacterium BB12Addition in baby milk powder is 105CFU/g-1010CFU/g, it is preferred that 106CFU/g- 108CFU/g, more preferably, 107CFU/g.
Main advantages of the present invention include:
(1) add in skim milk certain proportioning the prebiotics to infant intestinal beneficial (as FOS, GOS), OPO (OPO) and probiotic bacteria are (such as bacillus bifidus BB12), Can the bowel problems that improve infant of high degree (as colony balance, diarrhoea, constipation, antibiotic draw The side effect etc. risen).
(2) the bacillus bifidus BB added in baby milk powder product is disclosed first12It it is a kind of adhesive capacity By force, and have the probiotic bacteria slowing down antibiotic side effect.
Below in conjunction with specific embodiment, the present invention is expanded on further.Should be understood that these embodiments are merely to illustrate The present invention rather than restriction the scope of the present invention.The experiment side of unreceipted actual conditions in the following example Method, generally according to normal condition, or according to the condition proposed by manufacturer.Unless otherwise indicated, otherwise Percentage ratio and number are calculated by weight.
The Proportion of the active componend of the baby formula milk powder of embodiment 1 regulating intestinal canal function
The milk powder product of following proportioning is formed after with the addition of 4 kinds of active components in milk powder:
Skim milk 200-350ml
OPO (OPO) 9g
Oligofructose (FOS) 5g
Oligomeric galactose (GOS). 0.5g
Bifidobacterium BB12 107CFU/g
Embodiment 2 causes the effect of diarrhoea to improving infant antibiotic
Experimental technique:
167 childs (1-3 year) that antibiotic (such as cephalo) will be used to treat are randomly divided into A, B, C tri- Group.
A group: the milk powder product (Fos+Gos+BB of 42 people's embodiment 1 component proportions12+ OPO:5g+0.5g+1 ×107CFU/g+9g)
B group: 40 people Fos+Gos+BB12+ OPO:4g+0.5g+1 × 106CFU/g+9g
C group: 43 people Fos+Gos+OPO:5g+0.5g+9g
D group: 42 people FOS+GOS+BB12: 5g+0.5g+1 × 107CFU/g
Experimental period is 10 days, researchs and analyses 167 infantile diarrhea situations.The dilutest watery stool is abdomen Rushing down, yellow soft sample is just normal.
Experimental result (as shown in Figure 1): in 167 childs, A group diarrhoea number 2 people (4.8%), B group Diarrhoea number 6 people (15%), C group diarrhoea number 12 people (28.6%), D group diarrhoea number 5 people (11.9%)
Result shows, D group diarrhea rate is 2.5 times of A group;C group diarrhoea number is 6 times of A group, for B group 2 times;The diarrhea rate of B group is 3 times of A group.Therefore, the diarrhea rate of A group is minimum, and embodiment 1 component is joined The milk powder product of ratio can prevent or reduce the diarrhoea that antibiotic side effect produces.
The impact that baby intestinal flora is balanced by embodiment 3
Experimental technique:
With 68 childs as object of study, it is randomly divided into two groups:
Experimental group (36 people): the milk powder (Fos+Gos+BB of embodiment 1 component proportion12+OPO);
Matched group (32 people), this formula milk non-.
20 days were continued, by bifidobacteria viable bacteria in the method detection stool such as fluorescence in situ hybridization from the same day of being born Number change.
Experimental result (as shown in Figure 2):
Compared with matched group, in experimental group, bifidobacteria viable bacteria sum exceeds about 1 order of magnitude.
Result shows, the formula milk product of experimental group can effectively facilitate the bacillus bifidus propagation of intestinal, thus has Effect ground promotes intestinal microbial population balance.
The embodiment 4 effect to improving infant constipation
Experimental technique:
With 143 infant as object of study, it is randomly divided into three groups:
A group: the milk powder product (Fos+Gos+BB of 48 people's embodiment 1 component proportions12+OPO)
B group: 40 people Fos+Gos+BB12
C group: 43 people's brand milk powder, without above composition
Experimental period is 45 days, record defecation situation (normal defecation is a day 1-3 time, yellow soft shape of defecating).
Experimental result (as shown in Figure 3):
It is 83% that the natural law of A group infant normal defecation accounts for the ratio of total natural law, and stool is normal;B group is normal Defecation natural law accounts for total natural law 65%;C group normal defecation natural law accounts for total natural law 32%.
Result shows, A group can substantially reduce the constipation time, has remarkable result to improving constipation.
Embodiment 5 preparation technology
The present invention uses dry and wet hybrid technique to produce milk powder, and based on 100g baby formula milk powder, concrete steps are such as Under (carrying out the most successively):
Step one: dispensing, by fresh cow milk pasteurize 20 seconds under conditions of temperature is 72 DEG C, then sloughs fat Prepare skim milk, weigh the skim milk of the equal total dry solids weight of formula milk product.
Step 2: Fos with Gos weighed by predetermined ratio respectively mixes, is dissolved in pure water, stirs, And mix with other protides, carbohydrate as prebiotics mixed liquor, as liquid phase A.
Step 3: weigh OPO by predetermined ratio and mix with remaining vegetable oils and fats, as oil phase B.
Step 3: liquid phase A and oil phase B are added in the skimmed milk of pasteurize, temperature be 60 DEG C, Pressure is to carry out homogenizing under conditions of 20Mpa, cools down to room temperature afterwards.
Step 4: add vitamin, mineral successively, adjusts pH and Vc, and carries out multiple-effect evaporation operation.
Step 5: carry out homogenizing under conditions of pressure is 19Mpa, pressure be 18Mpa, temperature be 80-175 Carry out being spray-dried, cooling down to afterwards room temperature under conditions of DEG C, then carry out detection operation.
Step 6: add BB by predetermined ratio in intermediate store12Lyophilized powder, is stirred mixing operation, Make BB12Concentration in dry powder is 1 × 108CFU/g。
Step 7: packaging, uses vacuum nitrogen to carry out controlled atmospheric packing, joining of adjusted infant function of intestinal canal Side's milk powder product.
Step 8: detection.
The all documents mentioned in the present invention are incorporated as reference the most in this application, just as each document It is individually recited as with reference to like that.In addition, it is to be understood that after the above-mentioned teachings having read the present invention, The present invention can be made various changes or modifications by those skilled in the art, and these equivalent form of values fall within this Shen equally Please appended claims limited range.

Claims (10)

1. the baby formula milk powder product for regulating intestinal canal function, it is characterised in that containing following heavy The active component of amount part:
Milk 150-450
Vegetable oil lipoprotein 15-50
Prebiotics 1-12
Further, being also added with profitable probliotics, its addition is 105CFU/g-1010CFU/g, described addition (CFU/g) The amount of the probiotic bacteria for adding in every gram of milk powder product;
Wherein, described milk is 150-450:1-12:15-50 with prebiotics, the mass ratio of described Vegetable oil lipoprotein, The weight of Vegetable oil lipoprotein+prebiotics+probiotic bacteria accounts for the 2-30% of described milk powder product gross weight, and described cattle The weight portion of milk and described milk and prebiotics, described Vegetable oil lipoprotein mass ratio all with the weight in wet base of milk raw material Meter.
2. milk powder product as claimed in claim 1, it is characterised in that described prebiotics is selected from lower group: oligomeric Fructose (FOS), oligomeric galactose (GOS), oligomeric xylose (XOS), oligomeric lactulose (LACT), soybean oligo saccharide (SOS), inulin (Inulin) or a combination thereof.
3. milk powder product as claimed in claim 1, it is characterised in that described Vegetable oil lipoprotein is selected from lower group: certain herbaceous plants with big flowers Flower seed oil, Semen Maydis oil, soybean oil, walnut oil, Oleum Arachidis hypogaeae semen, OPO (OPO), Or a combination thereof.
4. milk powder product as claimed in claim 1, it is characterised in that described probiotic bacteria is selected from lower group: lactic acid Bacterium, bacillus bifidus, bacillus acidophilus or a combination thereof.
5. milk powder product as claimed in claim 1, it is characterised in that described milk powder product contains following weight The active component of part:
Wherein, described oligofructose (FOS) is 1-50:0.1-5 with the mass ratio of described oligomeric galactose (GOS); Described milk, oligofructose (FOS), oligomeric galactose (GOS) and described 1,3-bis-oleic acid 2-Palmic acid is sweet The mass ratio of oil three esters (OPO) is 150-450:0.8-8:0.2-2:4-12.
6. milk powder product as claimed in claim 5, it is characterised in that described milk powder product contains following weight The active component of part:
Wherein, described oligofructose (FOS) is 10-30:0.5-2 with the mass ratio of described oligomeric galactose (GOS); Described milk powder, oligofructose (FOS), oligomeric galactose (GOS) and described 1,3-bis-oleic acid 2-Palmic acid is sweet The mass ratio of oil three esters (OPO) is 200-400:1.5-7:0.4-1:5-10.
7. the baby formula milk powder product for regulating intestinal canal, it is characterised in that containing following weight portion Active component:
Wherein, described oligofructose (FOS) is 1-50:0.1-5 with the mass ratio of described oligomeric galactose (GOS); Described milk powder, oligofructose (FOS), oligomeric galactose (GOS) and described 1,3-bis-oleic acid 2-Palmic acid is sweet The mass ratio of oil three esters (OPO) is 150-450:0.8-8:0.2-2:4-12.
8. the milk powder product as described in claim 1-7 is arbitrary, it is characterised in that described milk powder product contains The concrete component of following weight portion:
Skim milk 200~350 Lactose 10~35 Vegetable oil 20~45 Concentrated lactoalbumin 10~20 Vitamin 0.5~5 Mineral 0.8~6 Fos+Gos 4~8 OPO 5~10
BB12 0.2~1 Nucleotide 0.05~1 DHA 0.02~0.5 ARA 0.02~0.8 Taurine 0.01~0.5 L-carnitine 0.001~0.1
9. the purposes of milk powder product as described in claim 1-8 is arbitrary, it is characterised in that described milk powder produces Product alleviate, for non-therapeutic, the diarrhoea that antibiotic causes.
10. the preparation method of milk powder product as described in claim 1-8 is arbitrary, it is characterised in that include following Step:
The inspection of (a) starting milk, clean breast, advance heat-sterilization, defat;
B () mixing FOS, GOS, obtain prebiotics mixed liquor;
C above-mentioned mixed liquor is mixed by () with other nutrients, form liquid phase A;
D OPO is mixed by () with remaining oils and fats, form oil phase B;
E the oil phase B of liquid phase A of step (c) and step (d) is added in skimmed milk by (), homogenizing, cold But;
F () adds vitamin, mineral in step (e), carry out multiple-effect evaporation;
(g) homogenizing, it is spray-dried, cools down;
H () adds bacillus bifidus BB12Lyophilized powder, obtains described milk powder product.
CN201510219569.1A 2015-04-30 2015-04-30 A kind of baby formula milk powder product for regulating intestinal canal function Pending CN106172794A (en)

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Cited By (4)

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CN106974267A (en) * 2017-04-10 2017-07-25 南昌大学 A kind of breast milk nutrition oil microcapsule powder preparation method
CN107197945A (en) * 2017-04-10 2017-09-26 南昌大学 A kind of allotment of breast milk nutrition oil and microcapsule preparation method
CN108467846A (en) * 2018-07-04 2018-08-31 中科宜康(北京)生物科技有限公司 The cultural method of lactobacillus acidophilus and its application
CN108782758A (en) * 2018-06-22 2018-11-13 陕西师范大学 A kind of fermented type synbiotic goat milk powder and preparation method thereof

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CN103621633A (en) * 2013-12-05 2014-03-12 刘保惠 Infant series yak milk formula milk powder and preparation method thereof
CN104430899A (en) * 2015-01-13 2015-03-25 光明乳业股份有限公司 Hypoallergenic infant formula milk powder and preparation method thereof

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CN101779703A (en) * 2010-04-09 2010-07-21 黑龙江省完达山乳业股份有限公司 Low-lactose milk powder and preparation method thereof
CN103621633A (en) * 2013-12-05 2014-03-12 刘保惠 Infant series yak milk formula milk powder and preparation method thereof
CN104430899A (en) * 2015-01-13 2015-03-25 光明乳业股份有限公司 Hypoallergenic infant formula milk powder and preparation method thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106974267A (en) * 2017-04-10 2017-07-25 南昌大学 A kind of breast milk nutrition oil microcapsule powder preparation method
CN107197945A (en) * 2017-04-10 2017-09-26 南昌大学 A kind of allotment of breast milk nutrition oil and microcapsule preparation method
CN108782758A (en) * 2018-06-22 2018-11-13 陕西师范大学 A kind of fermented type synbiotic goat milk powder and preparation method thereof
CN108782758B (en) * 2018-06-22 2022-03-08 浙江忠梦昌健康科技有限公司 Fermented synbiotic goat milk powder and preparation method thereof
CN108467846A (en) * 2018-07-04 2018-08-31 中科宜康(北京)生物科技有限公司 The cultural method of lactobacillus acidophilus and its application
CN108467846B (en) * 2018-07-04 2019-02-15 中科宜康(北京)生物科技有限公司 Probiotics solid beverage

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