CN104412075B - 用于分配流体的盒 - Google Patents

用于分配流体的盒 Download PDF

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Publication number
CN104412075B
CN104412075B CN201280074531.4A CN201280074531A CN104412075B CN 104412075 B CN104412075 B CN 104412075B CN 201280074531 A CN201280074531 A CN 201280074531A CN 104412075 B CN104412075 B CN 104412075B
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CN
China
Prior art keywords
pumping chamber
fluid
plunger
container
valve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201280074531.4A
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English (en)
Chinese (zh)
Other versions
CN104412075A (zh
Inventor
C·贝姆
P·库普泽
N·奥兰特
J·施品克
T·布吕克纳
T·克莱因
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
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F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CN104412075A publication Critical patent/CN104412075A/zh
Application granted granted Critical
Publication of CN104412075B publication Critical patent/CN104412075B/zh
Active legal-status Critical Current
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002—Reagent dispensers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0224—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
    • G01F11/021—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00871—Communications between instruments or with remote terminals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14216—Reciprocating piston type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16809—Flow controllers by repeated filling and emptying of an intermediate volume
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/065—Valves, specific forms thereof with moving parts sliding valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N2035/1025—Fluid level sensing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/119163—Automated chemical analysis with aspirator of claimed structure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Fluid Mechanics (AREA)
  • Hematology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Reciprocating Pumps (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Feeding And Controlling Fuel (AREA)
  • Loading And Unloading Of Fuel Tanks Or Ships (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
CN201280074531.4A 2012-05-08 2012-11-15 用于分配流体的盒 Active CN104412075B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12167108.5A EP2662671B1 (en) 2012-05-08 2012-05-08 Cartridge for dispensing a fluid
EP12167108.5 2012-05-08
PCT/EP2012/072733 WO2013167209A1 (en) 2012-05-08 2012-11-15 Cartridge for dispensing a fluid

Publications (2)

Publication Number Publication Date
CN104412075A CN104412075A (zh) 2015-03-11
CN104412075B true CN104412075B (zh) 2018-02-06

Family

ID=47191755

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280074531.4A Active CN104412075B (zh) 2012-05-08 2012-11-15 用于分配流体的盒

Country Status (7)

Country Link
US (2) US9341641B2 (enExample)
EP (2) EP2662671B1 (enExample)
JP (2) JP6240163B2 (enExample)
CN (1) CN104412075B (enExample)
CA (1) CA2872039C (enExample)
ES (2) ES2666795T3 (enExample)
WO (1) WO2013167209A1 (enExample)

Families Citing this family (17)

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Publication number Priority date Publication date Assignee Title
EP2868377B1 (en) 2013-10-31 2016-09-14 Roche Diagniostics GmbH Cartridge for stirring and dispensing a fluid, automatic analyzer and method of analyzing a biological sample
GB2524004A (en) * 2014-03-10 2015-09-16 Stratec Biomedical Ag Dispenser
EP3098606A1 (en) * 2015-05-29 2016-11-30 Roche Diagniostics GmbH Cartridge for dispensing particles and a reagent fluid
HUE045190T2 (hu) * 2015-07-13 2019-12-30 Iloq Oy Elektromechanikus zár mágneses térerõ használatával
US10351893B2 (en) * 2015-10-05 2019-07-16 GeneWeave Biosciences, Inc. Reagent cartridge for detection of cells
AU2016350506B2 (en) * 2015-11-04 2022-05-26 Nitto Denko Corporation Apparatus and system for biofluid sample dispensing and/or assay
EP3558037B1 (en) * 2016-12-23 2020-12-30 JT International SA Refilling system for aerosol inhaler
EP3354342A1 (en) * 2017-01-26 2018-08-01 Eidgenössische Anstalt für Wasserversorgung, Abwasserreinigung und Gewässerschutz, Eawag Device and method for producing individually processed fluid samples
JP7019303B2 (ja) * 2017-03-24 2022-02-15 東芝テック株式会社 液滴分注装置
CN107814077B (zh) * 2017-10-17 2018-12-18 浙江福赐德生物科技有限公司 实验用短暂性存储膏体的弹性囊结构
US11334956B2 (en) * 2019-07-31 2022-05-17 Itron, Inc. Vented utility meter enclosure
US11506522B2 (en) 2019-07-31 2022-11-22 Itron, Inc. Solar shield for utility meter
DE102019123200B4 (de) * 2019-08-29 2021-12-30 Marco Systemanalyse Und Entwicklung Gmbh Vorrichtung und verfahren zum zuführen eines flüssigen mediums
CN110510241B (zh) * 2019-09-10 2021-06-25 日照海关综合技术服务中心 一种剧毒试剂智能安全储存与取用装置
CN115552251A (zh) * 2020-05-22 2022-12-30 株式会社日立高新技术 自动分析装置及其组装辅助系统
US12310378B2 (en) 2020-06-29 2025-05-27 Jbt Marel Corporation Produce processing dosing system
CN116323670A (zh) 2020-09-22 2023-06-23 豪夫迈·罗氏有限公司 对α-1,6-核心-岩藻糖基化的PSA及其岩藻糖基化片段具有特异性的抗体

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US3753632A (en) * 1971-12-01 1973-08-21 A Mills Pump
US5441173A (en) * 1994-03-02 1995-08-15 Continental Baking Company Piston depositor
CN101384374A (zh) * 2006-02-21 2009-03-11 武藏工业株式会社 具备脱泡机构的液材吐出装置
CN101482571A (zh) * 2008-01-07 2009-07-15 霍夫曼-拉罗奇有限公司 试剂盒

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US4305531A (en) * 1978-09-21 1981-12-15 Dooley Dan W Pneumatically operated controlled volume dispensing device
JPS55146009A (en) * 1979-05-02 1980-11-14 Kanebo Shokuhin Kk Constant volume delivery unit
JPS56156799U (enExample) * 1980-04-24 1981-11-21
US4517302A (en) 1982-11-15 1985-05-14 Technicon Instruments Corporation Continuous flow metering apparatus
JPS5992356U (ja) 1982-12-11 1984-06-22 パロマ工業株式会社 燃焼器の不完全燃焼防止装置
JPH0477669A (ja) * 1990-07-20 1992-03-11 Nittec Co Ltd 自動分析装置
JPH0961216A (ja) * 1995-08-28 1997-03-07 Almex Inc 液体分注装置
US7501283B2 (en) * 2003-08-11 2009-03-10 Sakura Finetek U.S.A., Inc. Fluid dispensing apparatus
GB0424313D0 (en) * 2004-11-03 2004-12-01 Imi Norgren Ltd Liquid dispensing system
US7955392B2 (en) 2006-12-14 2011-06-07 Warsaw Orthopedic, Inc. Interspinous process devices and methods
JP4500822B2 (ja) 2007-02-19 2010-07-14 株式会社日立ハイテクノロジーズ 自動分析装置
ES2331546T3 (es) 2007-03-15 2010-01-07 F. Hoffmann-La Roche Ag Sistema de infusion con un dispositivo de dosificacion.
WO2010044788A1 (en) * 2008-10-15 2010-04-22 Hewlett-Packard Development Company, L.P. Fluid ejection cartridge

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3753632A (en) * 1971-12-01 1973-08-21 A Mills Pump
US5441173A (en) * 1994-03-02 1995-08-15 Continental Baking Company Piston depositor
CN101384374A (zh) * 2006-02-21 2009-03-11 武藏工业株式会社 具备脱泡机构的液材吐出装置
CN101482571A (zh) * 2008-01-07 2009-07-15 霍夫曼-拉罗奇有限公司 试剂盒

Also Published As

Publication number Publication date
HK1208261A1 (en) 2016-02-26
CA2872039A1 (en) 2013-11-14
US9341641B2 (en) 2016-05-17
US20150140669A1 (en) 2015-05-21
JP6647264B2 (ja) 2020-02-14
JP2015518572A (ja) 2015-07-02
ES2666795T3 (es) 2018-05-07
EP2662671A1 (en) 2013-11-13
EP2662671B1 (en) 2018-03-28
US20160231344A1 (en) 2016-08-11
CA2872039C (en) 2017-02-14
ES2666795T8 (es) 2018-05-21
JP2018031790A (ja) 2018-03-01
CN104412075A (zh) 2015-03-11
WO2013167209A1 (en) 2013-11-14
EP2847551B1 (en) 2020-09-02
EP2847551A1 (en) 2015-03-18
JP6240163B2 (ja) 2017-11-29
US10330693B2 (en) 2019-06-25
ES2829224T3 (es) 2021-05-31

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