CN104404076B - 利用锌指核酸酶敲除人乳头瘤病毒e6e7基因的方法 - Google Patents
利用锌指核酸酶敲除人乳头瘤病毒e6e7基因的方法 Download PDFInfo
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- CN104404076B CN104404076B CN201410648225.8A CN201410648225A CN104404076B CN 104404076 B CN104404076 B CN 104404076B CN 201410648225 A CN201410648225 A CN 201410648225A CN 104404076 B CN104404076 B CN 104404076B
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CN105535994B (zh) * | 2015-12-25 | 2018-01-19 | 华中科技大学同济医学院附属同济医院 | 一种治疗hpv感染的纳米粒制剂及其制备方法 |
CN109371021B (zh) * | 2018-07-02 | 2022-11-18 | 武汉凯德维斯生物技术有限公司 | 一种使用CRISPR/Cas9治疗HPV阳性的宫颈上皮内瘤变的方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1241636A (zh) * | 1999-07-05 | 2000-01-19 | 第一军医大学珠江医院 | 抗hpv16e6核酶质粒及其在人乳头瘤病毒与肿瘤治疗中的应用 |
WO2003040365A2 (de) * | 2001-11-08 | 2003-05-15 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Pna-konjugat oder pna-konjugat-gemisch zur therapie von mit hpv in zusammenhang stehenden erkrankungen |
WO2004002416A2 (en) * | 2002-06-26 | 2004-01-08 | The Penn State Research Foundation | Methods and materials for treating human papillomavirus infections |
CN103361328A (zh) * | 2012-03-30 | 2013-10-23 | 复旦大学 | 介导整合的hiv-1前病毒基因敲除的锌指核酸内切酶及其制法和应用 |
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Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1241636A (zh) * | 1999-07-05 | 2000-01-19 | 第一军医大学珠江医院 | 抗hpv16e6核酶质粒及其在人乳头瘤病毒与肿瘤治疗中的应用 |
WO2003040365A2 (de) * | 2001-11-08 | 2003-05-15 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Pna-konjugat oder pna-konjugat-gemisch zur therapie von mit hpv in zusammenhang stehenden erkrankungen |
WO2004002416A2 (en) * | 2002-06-26 | 2004-01-08 | The Penn State Research Foundation | Methods and materials for treating human papillomavirus infections |
CN103361328A (zh) * | 2012-03-30 | 2013-10-23 | 复旦大学 | 介导整合的hiv-1前病毒基因敲除的锌指核酸内切酶及其制法和应用 |
Non-Patent Citations (2)
Title |
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化学合成siRNA对宫颈癌细胞SiHa中E6基因表达的抑制作用;袁月秀等;《中国癌症杂志》;20071215;第17卷(第12期);第914-919页 * |
抗HPV16E_6与抗HPV18E_6核酶的设计、表达与活性鉴定;郑燕芳等;《解放军医学杂志》;19991030;第24卷(第5期);摘要,正文第2.1节 * |
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