CN104399006A - Traditional Chinese medicine mixture for treating paranoia schizophrenia - Google Patents
Traditional Chinese medicine mixture for treating paranoia schizophrenia Download PDFInfo
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- CN104399006A CN104399006A CN201410758593.8A CN201410758593A CN104399006A CN 104399006 A CN104399006 A CN 104399006A CN 201410758593 A CN201410758593 A CN 201410758593A CN 104399006 A CN104399006 A CN 104399006A
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Abstract
The invention discloses a traditional Chinese medicine mixture for treating paranoia schizophrenia. The traditional Chinese medicine mixture is characterized by being prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of immature bitter oranges, 10-30 parts of pinellia ternate, 10-30 parts of poria cocos, 15-40 parts of pumex, 10-30 parts of fritillaria praewalskii, 10-30 parts of dried tangerine or orange peel, 20-45 parts of vitriol curcuma aromatic, 10-35 parts of salvia miltiorrhiza, 10-30 parts of peach kernels, 5-15 parts of carthamus tinctorius, 5-15 parts of cattail pollen, 10-30 parts of curcuma zedoary, 10-30 parts of scutellaria baicalensis, 10-30 parts of cape jasmine, 10-30 parts of coptis chinensis, 15-40 parts of radix sophorae flavescentis, 10-30 parts of radix angelicae, 10-30 parts of mint, 5-15 parts of fructus forsythia, 3-10 parts of bamboo leaves, 5-20 parts of liquorice, 20-45 parts of rheum officinale, 0.3-1 part of cinnabar and 3-10 parts of amber. The traditional Chinese medicine mixture has the advantages of definite curative effect, good applicability to long-term taking, small side effect, high treatment rate, low reoccurrence rate after healing, and the like when being used for treating paranoia schizophrenia.
Description
Technical field:
The present invention relates to technical field of Chinese medicine, is exactly specifically a kind of Traditional Chinese drug mixture for the treatment of paranoid schizophrenia.
Background technology:
Paranoid schizophrenia is schizophrenia type the most common.The onset age is various compared with other is evening.Disease just shows as responsive suspicious, develops into vain hope gradually, and has extensive trend, and vain hope content is divorced from reality day by day.Sometimes can with hallucination and sensory perception resultant fault.Emotion and behavior often by hallucination and vain hope domination, show suspicious, fear more, even occur from injuring the behavior of hurting sb.'s feelings.This kind of disease comparatively other types is slow, and mental deterioration phenomenon is less obvious, and spontaneous remission person is less.Although then produce effects better through treatment, the health of existing drugs on patients all has larger injury.
Goal of the invention:
The present invention is exactly to overcome deficiency of the prior art, provides a kind for the treatment of for paranoid schizophrenia to have determined curative effect, be applicable to long-term taking, and the Traditional Chinese drug mixture that side effect is little.
The invention provides following technical scheme:
A kind of Traditional Chinese drug mixture for the treatment of paranoid schizophrenia, it is characterized in that being made up of the raw material of Chinese medicine of following composition by weight: Fructus Aurantii Immaturus 10-30 part, Rhizoma Pinelliae 10-30 part, Poria 10-30 part, Pumex 15-40 part, Bulbus Fritillariae Cirrhosae 10-30 part, Pericarpium Citri Reticulatae 10-30 part, vitriol Radix Curcumae 20-45 part, Radix Salviae Miltiorrhizae 10-35 part, Semen Persicae 10-30 part, Flos Carthami 5-15 part, Pollen Typhae 5-15 part, Rhizoma Curcumae 10-30 part, Radix Scutellariae 10-30 part, Fructus Gardeniae 10-30 part, Rhizoma Coptidis 10-30 part, Radix Sophorae Flavescentis 15-40 part, Radix Angelicae Dahuricae 10-30 part, Herba Menthae 10-30 part, Fructus Forsythiae 5-15 part, Folium Bambusae 3-10 part, Radix Glycyrrhizae 5-20 part, Radix Et Rhizoma Rhei 20-45 part, Cinnabaris 0.3-1 part, succinum 3-10 part.
Formula is preferably:
Fructus Aurantii Immaturus 15 parts, the Rhizoma Pinelliae 15 parts, 15 parts, Poria, Pumex 24 parts, Bulbus Fritillariae Cirrhosae 15 parts, Pericarpium Citri Reticulatae 12 parts, vitriol Radix Curcumae 30 parts, Radix Salviae Miltiorrhizae 20 parts, 15 parts, Semen Persicae, 10 parts, Flos Carthami, Pollen Typhae 10 parts, Rhizoma Curcumae 15 parts, Radix Scutellariae 15 parts, Fructus Gardeniae 15 parts, Rhizoma Coptidis 15 parts, Radix Sophorae Flavescentis 24 parts, the Radix Angelicae Dahuricae 15 parts, Herba Menthae 15 parts, Fructus Forsythiae 9 parts, 5 parts, Folium Bambusae, 10 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 30 parts, 0.5 part, Cinnabaris, succinum 3 parts.
Preparation method:
Component gets all raw material of Chinese medicine by weight, by Radix Et Rhizoma Rhei after screening is removed slag, Cinnabaris, succinum, Herba Menthae, Folium Bambusae takes out for subsequent use, the soak by water adding 8 times of weight in other medicines after 1.5 hours filtrate for subsequent use, the soak by water adding Folium Bambusae and Radix Et Rhizoma Rhei and 6 times of weight in medicinal residues after 1 hour filtrate for subsequent use, the soak by water adding Herba Menthae and 4 times of weight in medicinal residues decocts and the decoction filtrate of gained decoction liquor and first twice is merged for 45 minutes, then be condensed into dry extract, by dry extract and Cinnabaris, 800 order micropowders and Traditional Chinese drug mixture crude drug powder of the present invention is together ground into after succinum mixing, various conventional oral dosage formulations can be made in the medicament processing conventional for raw material passes through with this crude drug powder.
Make being described in detail as follows of each raw material of Chinese medicine of the present invention:
Fructus Aurantii Immaturus: bitter in the mouth, pungent, sour, warm in nature.Return spleen, stomach warp.There is dispelling the stagnated QI removing food stagnancy, effects such as loose painful abdominal mass of reducing phlegm.Be usually used in stagnant in stop, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock thoracic obstruction of expectorant, blocked-up chest; Gastroptosis, proctoptosis, the diseases such as uterine prolapse.
The Rhizoma Pinelliae: acrid in the mouth, warm in nature; Poisonous.Return spleen, stomach, lung meridian.There is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the diseases such as dissolving lump and resolving mass.Be usually used in abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, and vomiting regurgitation, breast gastral cavity painful abdominal mass is vexed, the diseases such as globus hystericus.
Poria: sweet in the mouth, light, property is put down.GUIXIN, lung, spleen, kidney channel.There is promoting diuresis to eliminate damp pathogen, the effects such as spleen invigorating mind calming.Be usually used in edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, and palpitation with fear insomnia waits disease.
Pumex: salty in the mouth; Cold in nature.Return lung; Kidney channel.There is clearing away lung-heat, change the effects such as old expectorant.Be usually used in the diseases such as cough due to lung-heat, old accumulation of phlegm block, goiter scrofula.
Bulbus Fritillariae Cirrhosae: bitter in the mouth, sweet, cold nature.Return lung, heart channel.There are clearing heat and moistening lung, the effects such as preventing phlegm from forming and stopping coughing.Be usually used in lung-heat type cough, the few expectorant of dry cough, deficiency of YIN chronic cough, the diseases such as sputum with blood.
Pericarpium Citri Reticulatae: bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.There is regulating qi-flowing for strengthening spleen, the effects such as drying dampness to eliminate phlegm.Be usually used in fullness in the epigastrium and chest, lack of appetite and vomiting, the diseases such as cough with copious phlegm.
Vitriol Radix Curcumae: namely Radix Curcumae adds alum water, uses low baking temperature fried dry, to being strong yellow gained.This product acrid in the mouth, hardship, cold in nature.Return liver, the heart, lung meridian.There is regulating qi to disperse stagnation, heart fire-clearing upset-relieving, the effects such as promoting the function of the gallbladder to alleviate jaundice.Be usually used in for amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, the diseases such as epilepsy is gone mad, jaundice dark coloured urine.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature.GUIXIN, Liver Channel.Have stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire the effects such as relieving restlessness.Be usually used in menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, the diseases such as angina pectoris.
Semen Persicae: bitter in the mouth, sweet, property is put down.GUIXIN, liver, large intestine channel.There is blood circulation promoting and blood stasis dispelling, the effects such as loosening bowel to relieve constipation.Be usually used in amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, the diseases such as dryness of the intestine constipation.
Flos Carthami: acrid in the mouth, warm in nature.GUIXIN, Liver Channel.There is promoting blood circulation to restore menstrual flow, the effects such as eliminating stasis to stop pain.Be usually used in amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection such as to swell and ache the disease.
Pollen Typhae: sweet in the mouth, property is put down.Return liver, pericardium channel.There is hemostasis, blood stasis dispelling, the effect such as treating stranguria.Be usually used in spitting blood, epistaxis, spitting of blood, metrorrhagia, traumatic hemorrhage, amenorrhea dysmenorrhea, gastral cavity ventral spine pain, tumbling and swelling, the diseases such as blood strangury and dry pain.
Rhizoma Curcumae: acrid in the mouth, hardship, warm in nature.Return liver, spleen channel.There is circulation of qi promoting removing blood stasis, the effects such as removing food stagnancy pain relieving.Be usually used in Dan abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; The diseases such as early cervical carcinoma.
Radix Scutellariae: bitter in the mouth, cold in nature.Return lung, gallbladder, spleen, large intestine, small intestine meridian.There is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Be usually used in hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, the diseases such as frequent fetal movement.
Fructus Gardeniae: bitter in the mouth, cold in nature.GUIXIN, lung, tri-jiao channel.There is heat clearing away, pathogenic fire purging, the effects such as removing heat from blood.Be usually used in calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains diseases such as swelling and ache
Rhizoma Coptidis: bitter in the mouth, cold in nature.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.There is heat clearing and damp drying, the effects such as eliminating fire and detoxication.Be usually used in damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus such as to be suppurated the disease.
Radix Sophorae Flavescentis: bitter in the mouth, cold in nature.GUIXIN, liver, stomach, large intestine, urinary bladder channel.There is heat clearing and damp drying, parasite killing, the effects such as diuresis.Be usually used in hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, the diseases such as trichomonal vaginitis.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature.Return stomach, large intestine, lung meridian.There is the dehumidifying of loose wind, understand things pain-stopping, the effects such as detumescence and apocenosis.Be usually used in headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection such as to swell and ache the disease.
Herba Menthae: acrid in the mouth, cool in nature.Return lung, Liver Channel.There is dispelling wind-heat.Refresh oneself, the effects such as rash.Be usually used in anemopyretic cold, pathogenic wind-warm from the beginning of, headache, conjunctival congestion, sore throat, aphtha, rubella, measles, disease such as breast side of body feeling of distension and oppression etc.
Fructus Forsythiae: bitter in the mouth, cold nature.Return lung, the heart, small intestine meridian.There is heat-clearing and toxic substances removing, the effects such as dispersing swelling and dissipating binds.Be usually used in carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly to join the army, high hot excessive thirst, the diseases such as coma sends out speckle, pyretic stranguria urine retention.
Folium Bambusae: sweet in the mouth, light, cold in nature.GUIXIN, lung, stomach warp.There is clearing heat and relieving fidgetness; To promote the production of body fluid the effects such as diuresis.Be usually used in calentura excessive thirst, little Jing Epilepsy, cough with dyspnea tell the diseases such as nosebleed, oliguria with reddish urine, erosion of the oral mucosa tongue boil.
Radix Glycyrrhizae: sweet in the mouth, property is put down.GUIXIN, lung, spleen, stomach warp.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effects such as coordinating the actions of various ingredients in a prescription.Be usually used in weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, the disease such as strong.
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature.Return spleen, stomach, large intestine, liver, pericardium channel.There is purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, the effects such as eliminating blood stasis and inducing menstruation.Be usually used in excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; The diseases such as upper gastrointestinal hemorrhage.
Cinnabaris: sweet in the mouth, cold nature; Poisonous.GUIXIN warp.Have clear away heart-fire relieving convulsion, effects such as removing toxic substances of calming the nerves.Be usually used in palpitation and being susceptible to fright, insomnia and dreamful sleep, epilepsy is gone mad, infantile convulsion, blurring of vision, aphtha, sore throat, the diseases such as sore swollen toxin.
Succinum: sweet in the mouth, property is put down.GUIXIN, liver, small intestine meridian.Have tranquillizing the mind by relieving convulsion, dissipating blood stasis stops blooding, the effects such as relieving stranguria by diuresis.Be usually used in infantile convulsion epilepsy, palpitation with fear insomnia, stranguria with blood hematuria, urinary obstruction, women's amenorrhea, stop the stasis of blood stomachache puerperal, skin sore, the diseases such as traumatic injuries.
Inventor thinks: people's natural endowment in congenital, by affecting of contained predetermined substance basis in father and mother's essential substance for reproduction, the specific constitutional type in inborn genetic; Namely have much its previous generation's idiosyncrasy, and its previous generation of tool send out susceptible, the easily natural disposition of some disease causative agent, and this disease pathology tendentiousness easily, manic-depressive psychosis is as the same.This disease belongs to epilepsy, affecting by inherited genetic factors, the susceptible of patient self tool natural endowment schizophrenia paranoid type virulence factor expectorant, easily natural disposition, and this kind of pathology tendentiousness easily sent out; And the negative body constitution of many tools and flexible makings.From being born, no matter diseases caused by exogenous pathogenic factor, internal injury, or other paathogenic factor, all can make internal organs gasification function not normal, accumulate wet hydrops and be expectorant; The expectorant of giving birth to by quiet slow the affecting of negative body constitution, manyly centripetally in deep sticky shape slowly to move, thisly slowly changing resistance of becoming silted up, block up blood fortune and raw blood stasis, poly-with expectorant dirt again after the stasis of blood is raw, further weighed centripetal heavily heavy slowness of dividing a word with a hyphen at the end of a line, caused the expectorant stasis of blood and become silted up of a specified duration strongly fragrant dirty and make poison.So expectorant, the stasis of blood, poison are the major pathogenetic factor of schizophrenia paranoid type morbidity and Disease evolution.
Inventor, according to above-mentioned thought, selects natural Chinese medicines raw material, through reasonable compatibility, give full play to drug effect, make the present invention have determined curative effect for the treatment of paranoid schizophrenia, be applicable to long-term taking, side effect is little, and cure rate is high, controls the advantages such as recurrence rate after healing.
Detailed description of the invention:
Embodiment 1:
Treat a paranoid schizophrenia's Traditional Chinese drug mixture, it is characterized in that being made up of the raw material of Chinese medicine of following composition by weight: Fructus Aurantii Immaturus 15 parts, the Rhizoma Pinelliae 15 parts, 15 parts, Poria, Pumex 24 parts, Bulbus Fritillariae Cirrhosae 15 parts, Pericarpium Citri Reticulatae 12 parts, vitriol Radix Curcumae 30 parts, Radix Salviae Miltiorrhizae 20 parts, 15 parts, Semen Persicae, 10 parts, Flos Carthami, Pollen Typhae 10 parts, Rhizoma Curcumae 15 parts, Radix Scutellariae 15 parts, Fructus Gardeniae 15 parts, Rhizoma Coptidis 15 parts, Radix Sophorae Flavescentis 24 parts, the Radix Angelicae Dahuricae 15 parts, Herba Menthae 15 parts, Fructus Forsythiae 9 parts, 5 parts, Folium Bambusae, 10 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 30 parts, 0.5 part, Cinnabaris, succinum 3 parts.
Embodiment 2:
Treat a paranoid schizophrenia's Traditional Chinese drug mixture, it is characterized in that being made up of the raw material of Chinese medicine of following composition by weight: Fructus Aurantii Immaturus 10 parts, the Rhizoma Pinelliae 10 parts, 10 parts, Poria, Pumex 15 parts, Bulbus Fritillariae Cirrhosae 10-30 part, Pericarpium Citri Reticulatae 10 parts, vitriol Radix Curcumae 20 parts, Radix Salviae Miltiorrhizae 10 parts, 10 parts, Semen Persicae, 5 parts, Flos Carthami, Pollen Typhae 5 parts, Rhizoma Curcumae 10 parts, Radix Scutellariae 10 parts, Fructus Gardeniae 10 parts, Rhizoma Coptidis 10 parts, Radix Sophorae Flavescentis 15 parts, the Radix Angelicae Dahuricae 10 parts, Herba Menthae 10 parts, Fructus Forsythiae 5 parts, 5 parts, Folium Bambusae, 10 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 20 parts, 0.3 part, Cinnabaris, succinum 4 parts.
Embodiment 3:
Treat a paranoid schizophrenia's Traditional Chinese drug mixture, it is characterized in that being made up of the raw material of Chinese medicine of following composition by weight: Fructus Aurantii Immaturus 25 parts, the Rhizoma Pinelliae 20 parts, 25 parts, Poria, Pumex 40 parts, Bulbus Fritillariae Cirrhosae 20 parts, Pericarpium Citri Reticulatae 30 parts, vitriol Radix Curcumae 30 parts, Radix Salviae Miltiorrhizae 30 parts, 23 parts, Semen Persicae, 15 parts, Flos Carthami, Pollen Typhae 15 parts, Rhizoma Curcumae 22 parts, Radix Scutellariae 22 parts, Fructus Gardeniae 24 parts, Rhizoma Coptidis 26 parts, Radix Sophorae Flavescentis 36 parts, the Radix Angelicae Dahuricae 27 parts, Herba Menthae 24 parts, Fructus Forsythiae 13 parts, 8 parts, Folium Bambusae, 17 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 20 parts, 0.7 part, Cinnabaris, succinum 6 parts.
Embodiment 1-3 all adopts following preparation and method of administration:
Component gets all raw material of Chinese medicine by weight, by Radix Et Rhizoma Rhei after screening is removed slag, Cinnabaris, succinum, Herba Menthae, Folium Bambusae takes out for subsequent use, the soak by water adding 8 times of weight in other medicines after 1.5 hours filtrate for subsequent use, the soak by water adding Folium Bambusae and Radix Et Rhizoma Rhei and 6 times of weight in medicinal residues after 1 hour filtrate for subsequent use, the soak by water adding Herba Menthae and 4 times of weight in medicinal residues decocts and the decoction filtrate of gained decoction liquor and first twice is merged for 45 minutes, then be condensed into dry extract, by dry extract and Cinnabaris, 800 order micropowders and Traditional Chinese drug mixture crude drug powder of the present invention is together ground into after succinum mixing, various conventional oral dosage formulations can be made in the medicament processing conventional for raw material passes through with this crude drug powder.
Take medicine every day 4 times, contain 12-16 gram of crude drug powder each serving in medicament.Period in a medicine is taken a good rest, the food such as rich, pungent and saccharide of diet.
Model case:
Patient Liu so-and-so, man 26 years old, patient is introverted from preschool period, hypologia how quiet, often quiet and scan all, meet thing to ask, therefore institute's language is proper and distinct more, aobvious sensible wise, has the title of " little adult " more; So stiff, stubborn, good difficult and sulky; After admission, study with all worries set aside, affects by its flexible makings, and like to bore a difficult problem, school grade is very good.There is hallucination when within 2 years, being 24 years old afterwards in patient work, originally household does not take notice of, within then 3 months, PD is rapid, cannot work.Through hospital, confirmation is paranoid schizophrenia, take multi-medicament treatment, but drug dependence comparatively greatly, certain side effect also appears in patient body in addition.Therefore start to take Traditional Chinese drug mixture of the present invention, patient consumes is over 3 months, and spiritual sign is normal, and without any untoward reaction on health, and period in a medicine has two to leave behind medicine because going out, and disconnected medicine does not have disease to send out on the 2nd yet.The patient mental over one year that takes medicine is better, and life is normal, does not occur hallucination again.
Claims (3)
1. treat the Traditional Chinese drug mixture of paranoid schizophrenia for one kind, it is characterized in that being made up of the raw material of Chinese medicine of following composition by weight: Fructus Aurantii Immaturus 10-30 part, Rhizoma Pinelliae 10-30 part, Poria 10-30 part, Pumex 15-40 part, Bulbus Fritillariae Cirrhosae 10-30 part, Pericarpium Citri Reticulatae 10-30 part, vitriol Radix Curcumae 20-45 part, Radix Salviae Miltiorrhizae 10-35 part, Semen Persicae 10-30 part, Flos Carthami 5-15 part, Pollen Typhae 5-15 part, Rhizoma Curcumae 10-30 part, Radix Scutellariae 10-30 part, Fructus Gardeniae 10-30 part, Rhizoma Coptidis 10-30 part, Radix Sophorae Flavescentis 15-40 part, Radix Angelicae Dahuricae 10-30 part, Herba Menthae 10-30 part, Fructus Forsythiae 5-15 part, Folium Bambusae 3-10 part, Radix Glycyrrhizae 5-20 part, Radix Et Rhizoma Rhei 20-45 part, Cinnabaris 0.3-1 part, succinum 3-10 part.
2., according to a kind of Traditional Chinese drug mixture for the treatment of paranoid schizophrenia described in claim 1, it is characterized in that being made up of the raw material of Chinese medicine of following composition by weight: Fructus Aurantii Immaturus 15 parts, the Rhizoma Pinelliae 15 parts, 15 parts, Poria, Pumex 24 parts, Bulbus Fritillariae Cirrhosae 15 parts, Pericarpium Citri Reticulatae 12 parts, vitriol Radix Curcumae 30 parts, Radix Salviae Miltiorrhizae 20 parts, 15 parts, Semen Persicae, 10 parts, Flos Carthami, Pollen Typhae 10 parts, Rhizoma Curcumae 15 parts, Radix Scutellariae 15 parts, Fructus Gardeniae 15 parts, Rhizoma Coptidis 15 parts, Radix Sophorae Flavescentis 24 parts, the Radix Angelicae Dahuricae 15 parts, Herba Menthae 15 parts, Fructus Forsythiae 9 parts, 5 parts, Folium Bambusae, 10 parts, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 30 parts, 0.5 part, Cinnabaris, succinum 3 parts.
3. treat the preparation method of the Traditional Chinese drug mixture of paranoid schizophrenia for one kind, it is characterized in that comprising the following steps: component gets all raw material of Chinese medicine by weight, by Radix Et Rhizoma Rhei after screening is removed slag, Cinnabaris, succinum, Herba Menthae, Folium Bambusae takes out for subsequent use, the soak by water adding 8 times of weight in other medicines after 1.5 hours filtrate for subsequent use, the soak by water adding Folium Bambusae and Radix Et Rhizoma Rhei and 6 times of weight in medicinal residues after 1 hour filtrate for subsequent use, the soak by water adding Herba Menthae and 4 times of weight in medicinal residues decocts and the decoction filtrate of gained decoction liquor and first twice is merged for 45 minutes, then be condensed into dry extract, by dry extract and Cinnabaris, 800 order micropowders and Traditional Chinese drug mixture crude drug powder of the present invention is together ground into after succinum mixing, various conventional oral dosage formulations can be made in the medicament processing conventional for raw material passes through with this crude drug powder.
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Citations (2)
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CN101422571A (en) * | 2008-12-09 | 2009-05-06 | 昝圣旭 | Psychosis positive four-step therapeutics series medicine |
CN101700330A (en) * | 2009-11-11 | 2010-05-05 | 宋爱民 | Traditional Chinese medicinal capsules for treating schizophrenia |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN101422571A (en) * | 2008-12-09 | 2009-05-06 | 昝圣旭 | Psychosis positive four-step therapeutics series medicine |
CN101700330A (en) * | 2009-11-11 | 2010-05-05 | 宋爱民 | Traditional Chinese medicinal capsules for treating schizophrenia |
Non-Patent Citations (1)
Title |
---|
丁德正: "从痰、瘀、毒论治偏执型精神分裂症", 《中医药临床杂志》 * |
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