CN104398998A - 一种治疗泌尿系结石的中药组合物 - Google Patents

一种治疗泌尿系结石的中药组合物 Download PDF

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CN104398998A
CN104398998A CN201410750177.3A CN201410750177A CN104398998A CN 104398998 A CN104398998 A CN 104398998A CN 201410750177 A CN201410750177 A CN 201410750177A CN 104398998 A CN104398998 A CN 104398998A
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李穆
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Abstract

本发明公开了一种治疗泌尿系结石的中药组合物，该中药包括以下重量份数的原料药制成：杜仲15-30份、胡桃仁20-25份、金钱草9-35份、鸡内金3-45份、海金沙10-30份、甘草6-10份、鱼脑石12-20份、琥珀1-12份、泽泻10-30份、石苇10-30份、瞿麦8-20份、王不留行10-30份、滑石7-30份、牛膝25-30份、玉米须9-30份、冬葵子6-12份、扁蓄8-12份、小蓟18-22份、浮石9-15份、土狗子10-30份、穿破石10-60份、威灵仙3-30份、三棱15-20份、莪术15-20份、乌药6-15份、元胡6-10份和地龙10—20份。本发明药物采取诸药合用、清热袪湿、溶石破石、利尿消肿止痛、通淋排石，有利于结石的排出，本发明中药无毒副作用，费用低廉，总有效率达到100%。

Description

一种治疗泌尿系结石的中药组合物
技术领域
本发明涉及一种治疗泌尿系结石的中药组合物。 
背景技术
泌尿系统结石是一种常见病，它包括肾结石、输尿管结石、膀胱结石、尿道结石。由于此类病的发病率高，临床症状主要表现为肾绞痛、胀痛和血尿等，同时伴有尿频，尿急，尿痛等尿路刺激症。目前，西医对于泌尿系结石形成的机理尚不能完全明了。肾代谢功能的紊乱，可能是主要的原因之一。西医在治疗上效果也不理想。碎石，禁忌症多，手术，创伤大，复发率高。 
现在市场上用于治疗结石的中药和西药多种多样，在服用时药性较慢，疗程较长，治愈率不高，且市场上的药物大多只能缓解病情，不能治愈，有些药物有较大的副作用，患者需要长期服用药物，治疗效果不理想。 
发明内容： 
    本发明所要解决的技术问题是提供一种更好的治疗效果、治愈率高、毒副作用小的中药组合物。
    本发明采用如下技术方案：本发明是采用如下重量份数比组分制成的：杜仲15-30份、胡桃仁20-25份、金钱草9-35份、鸡内金3-45份、海金沙10-30份、甘草6-10份、鱼脑石12-20份、琥珀1-12份、泽泻10-30份、石苇10-30份、瞿麦8-20份、王不留行10-30份、滑石7-30份、牛膝25-30份、玉米须9-30份、冬葵子6-12份、扁蓄8-12份、小蓟18-22份、浮石9-15份、土狗子10-30份、穿破石10-60份、威灵仙3-30份、三棱15-20份、莪术15-20份、乌药6-15份、元胡6-10份和地龙10—20 份。 
    优选各原料药的重量份为：杜仲18份、胡桃仁22份、金钱草20份、鸡内金30份、海金沙20份、甘草7份、鱼脑石16份、琥珀6份、泽泻20份、石苇24份、瞿麦16份、王不留行16份、滑石18份、牛膝26份、玉米须17份、冬葵子8份、扁蓄10份、小蓟21份、浮石10份、土狗子20份、穿破石45份、威灵仙8份、三棱17份、莪术17份、乌药9份、元胡7份和地龙15 份。 
本发明积极效果如下： 
本发明药物组合物中：
杜仲：甘微辛，性温。功能：补肝肾，强筋骨，分解体内胆固醇，降低体内脂肪，恢复血管弹性，利尿清热。
胡桃仁：味甘，性温。功能：入肺肾经，补肾强腰，有溶化结石的作用。 
金钱草：味甘、微苦，性凉。归肝、胆、肾、膀胱经。功能主治：利水通淋；清热解毒；散瘀消肿。主治肝胆及泌尿系结石；热淋；肾炎水肿；湿热黄疸；疮毒痈肿；毒蛇咬伤；跌打损伤。 
鸡内金：性甘平、微寒、无毒，归脾、胃、肾、膀胱经。主治：可消食健胃，涩精止遗，化石。消积滞，健脾胃。治食积胀满，呕吐反胃，泻痢，疳积，消渴，遗溺，喉痹乳蛾，牙疳口疮。 
海金沙：味甘，性寒。归膀胱、小肠经。主治：淋证。本品其性下降，善清小肠、膀胱湿热，尤善止尿道疼痛，为治诸淋涩痛之要药。全草：兼能清热解毒。除治淋证，用于痈肿疮毒、痄腮和黄疸。 
甘草：甘草性平，味甘，归十二经。功能：补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。 
鱼脑石：味咸，性平。功用主治：化石，通淋，消炎。治石淋，小便不利，中耳炎，鼻炎，脑漏。 
琥珀：味甘，性平。功能：归心、肝、小肠、膀胱、肺、脾经。镇惊安神；散瘀止血；利水通淋；去翳明目。主惊悸失眠；惊风癫痫；血淋血尿；血滞经闭；产后瘀滞腹痛；症瘕积聚；目生障翳；痈肿疮毒。 
泽泻：味甘、淡，性寒；归肾、膀胱经。功能：利水渗湿；泄热通淋。主小便不利；热淋涩痛；水肿胀满；泄泻；痰饮眩晕；遗精。 
石韦：味辛，性平。功能：利水通淋，清肺泄热。治淋痛，尿血，尿路结石，肾炎，崩漏，痢疾，肺热咳嗽，慢性气管炎，金疮，痈疽。 
瞿麦：苦，寒。入心、肾、小肠经。功能主治：利尿通淋，破血通经。用于热淋、血淋、石淋、小便不通、淋沥涩痛、增长经。 
王不留行：味苦，性平;归肝、胃经;入血分，直而不守。主治：血瘀痛经，经闭，乳汁不通，乳痈疮肿，淋症，小便不利。 
滑石：血瘀痛经，经闭，乳汁不通，乳痈疮肿，淋症，小便不利。功能：热淋，治暑热烦渴，小便不利，水泻，热痢，淋病，黄疸，水肿，衄血，脚气，皮肤湿烂。 
牛膝：苦；酸；性平。主治：原植物腰膝酸痛；下肢痿软；血滞经闭；痛经；产后血瘀腹痛；症瘕；胞衣不下；热淋；血淋；跌打损伤；痈肿恶疮；咽喉肿痛。 
玉米须：性平，味甘淡，无毒。入肝、肾、膀胱经。功能：利尿，泄热，平肝，利胆。治肾炎水肿，脚气，黄疸肝炎，高血压，胆囊炎，胆结石，糖尿病，吐血衄血，鼻渊，乳痈。 
冬葵子：味甘苦，性微寒，无毒。归经：入大小肠、膀胱经。功能主治：利水，滑肠，下乳。治二便不通，淋病，水肿，妇女乳汁不行，乳房肿痛。 
扁蓄：苦，微寒。归膀胱经。主治：①利水通淋用于湿热淋证，可治疗泌尿系感染、结石、血尿等；②杀虫止痒 可治疗蛲虫等寄生虫病。亦可煎汤外洗治疗皮肤疮疹、瘙痒；③治赤白痢，黄疸。 
小蓟：甘、凉。入肝经。功能：凉血、止血。功同大蓟而力弱，且不如大蓟之善消痈肿。主治：吐血、尿血、外伤出血、传染性肝炎、肝肿大。 
土狗子：干燥的虫体，多已碎断而少完整。具有利尿，消肿，解毒之功效。临床用于治疗泌尿系结石、水肿、肝硬化腹水、慢性肾炎和尿毒症、胞衣不下，手术后尿潴留及肠和膀胱痹引起的二便不通，敷退入肉的铁钉、木竹和异物等。 
穿破石：味淡；微苦；性凉。入心经、肝经。功能：祛风通络；清热除湿；解毒消肿。主治：风湿痹痛；跌打损伤；黄疽；腮腺炎；肺结核；胃和十二指肠溃疡；淋浊；蛊胀；闭经；劳伤咳血；疗疮痈肿。 
威灵仙：辛咸，温，有毒。入肺、肾二经。主治风湿痹痛，肢体麻木，筋脉拘挛，屈伸不利，脚气肿痛，疟疾，骨哽咽喉，并治痰饮积聚。 
三棱：苦辛，平。入肝。脾经。功能：破血，行气，消积，止痛。治癥瘕积聚，气血凝滞，心腹疼痛，胁下胀疼，经闭，产后瘀血腹痛，跌打损伤。疮肿坚硬。 
莪术：辛、苦，温。归肝、脾经。功能：破血行气，消积止痛。祛风除湿，消肿止痛。用于风湿痛，头风痛，胸胁痛，腹泻痛；外用治跌打损伤，瘀血肿痛。 
地龙：性寒，味咸。归肝、胃、肺、膀胱经。功能：清热平肝、熄风止痉、平喘、利尿、通络除痹。主治：主治高热烦躁、惊痫抽搐、肺热喘咳、热结尿闭、痹痛肢麻、半身不遂，以及疮疡肿毒等证。 
浮石：咸；寒；无毒。肺；肾；肝；大肠经。功能：清肺火；化老痰；利水通淋；软坚散结。主痰热壅肺；咳喘痰稠难咯；小便淋沥涩痛。 
乌药：味辛，性温；归脾、胃、肝、肾、膀胱经。功能：行气止痛；温肾散寒。主胸胁满闷；脘腹胀痛；头痛；寒疝疼痛；痛经及产后腹痛；尿频；遗尿。 
元胡：辛、苦、温。归肝、脾、心经。功效：活血、行气、止痛。主要用于血瘀气滞诸痛证。 
本发明药物中鱼脑石、玉米须、鸡内金、胡桃仁、金钱草、杜仲入肺肾经，补肾强腰，溶化结石，扶正固本为君药；配以浮石、王不留行、瞿麦、石苇、泽泻、穿破石、海金沙、滑石、土狗子、扁蓄利水通淋、消肿解毒为臣药；辅以牛膝、威灵仙、地龙、小蓟、三棱、莪术、乌药、元胡、玉米须利尿，破血行瘀，行气、止痛为佐药；调以甘草为使药，诸药合用，可达活血化瘀、消石利尿、清热利湿、缓解止痛之功效。 
本发明的用法用量是：按优选方案配药，以克为单位。取上述方药先用凉水浸泡1小时。第一遍武火煮沸，改文火再煮沸40 分钟，滤出药液；第二遍武火煮沸，改文火再煮沸60 分钟，滤出药液。两遍药液混合，一日内，分两次服用，每次在饭前半小时服用，每日一剂，两周为一疗程。 
本方孕妇忌服，除孕妇外，对普遍的泌尿系统结石症均具有一定的疗效。结石越久越大，服用本方的时间及剂量应越多。一般结石小于1cm 的，服用本发明8剂后，结石的清除达到比较满意的效果。 
采用本发明药物组合物治疗泌尿系结石病200例，男160例，女40例，肾结石患者85例，输尿管结石39例，膀胱泥沙状结石76例，年龄在18-70岁，采用本发明均有疗效，以下列举几个具体例子对本发明做进一步阐释，但本发明并不限于此特定例子。 
诊断标准： 
超声检查：临床症状为肾绞痛、胀痛和血尿。
疗效评定标准： 
治愈：临床症状完全消失，超声波复查结石排出体外。
显效：临床症状基本消失，超声波复查结石缩小，结石仍部分存在。 
无效：临床症状未见明显消失或减轻，超声波复查结石未排出体外。 
治愈68 例，显效120例，无效12 例，治愈率34%，显效率60%，无效率6%。 
典型病例： 
1.    王某，男，40岁，服药前右下腹部剧痛，入住本市三等家甲级医院，住院9天，具体用中西药不详。现右下腹不痛，但B超证实右侧输尿管结石存在，结石大小0.7cm×0.5cm×0.3cm。经服用本发明药物10 剂后，有泥沙样结石排出，经B超检查证实，结石不存在。
2.    刘某，男，23岁，学生，有腹部钝痛，经B超证实，膀胱泥沙状结石：0.7cm×0.5cm×0.4cm。服用本发明药物15剂后，经B超检测痊愈。 
3.    卜某，男，58岁，右腹部钝痛，右肾结石：1.1cm×0.8cm×0.6cm，服用本发明药物20剂后，结石排出，经B 超检验，结石不存在，痊愈。 
  
本发明具体实施例如下表示：
 

Claims (2)

1.一种治疗泌尿系结石的中药组合物，其特征在于其包括以下重量份数的中药原料：杜仲15-30份、胡桃仁20-25份、金钱草9-35份、鸡内金3-45份、海金沙10-30份、甘草6-10份、鱼脑石12-20份、琥珀1-12份、泽泻10-30份、石苇10-30份、瞿麦8-20份、王不留行10-30份、滑石7-30份、牛膝25-30份、玉米须9-30份、冬葵子6-12份、扁蓄8-12份、小蓟18-22份、浮石9-15份、土狗子10-30份、穿破石10-60份、威灵仙3-30份、三棱15-20份、莪术15-20份、乌药6-15份、元胡6-10份和地龙10—20 份。
2.  根据权利要求1所述的一种治疗泌尿系结石的中药组合物，其特征是各原料药的重量份为：杜仲18份、胡桃仁22份、金钱草20份、鸡内金30份、海金沙20份、甘草7份、鱼脑石16份、琥珀6份、泽泻20份、石苇24份、瞿麦16份、王不留行16份、滑石18份、牛膝26份、玉米须17份、冬葵子8份、扁蓄10份、小蓟21份、浮石10份、土狗子20份、穿破石45份、威灵仙8份、三棱17份、莪术17份、乌药9份、元胡7份和地龙15 份。
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CN105497782A (zh) * 2015-12-18 2016-04-20 夏修菲 一种用于治疗肾石症的中药丸剂及制备方法
CN106236902A (zh) * 2016-08-23 2016-12-21 吴斌 一种用于治疗泌尿系结石的药物
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CN106620366A (zh) * 2017-03-21 2017-05-10 聊城大学 一种治疗膀胱结石的中药缓释片及制备方法
CN107243054A (zh) * 2017-06-13 2017-10-13 孔庆 一种治疗泌尿系统结石的中药及其制备方法
CN110680887A (zh) * 2019-10-09 2020-01-14 江西沐恩堂生物科技有限公司 一种地龙除结石药酒及其制备方法

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