CN104383199A - Traditional Chinese medicine used for treating chronic hepatitis - Google Patents
Traditional Chinese medicine used for treating chronic hepatitis Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention relates to traditional Chinese medicine used for treating chronic hepatitis. The traditional Chinese medicine is prepared from the following raw material drugs in parts by weight: 10 parts of radix glehniae, 8 parts of radix rehmanniae, 9 parts of radix polygoni multiflori preparata, 6 parts of stir-fried scutellaria, 9 parts of stir-fried white peony roots, 6 parts of szechwan chinaberry fruits, 6 parts of processed radix aconiti lateralis, 6 parts of fructus evodiae, 6 parts of seeds of European hemlock roots. Clinical experiment results prove that the traditional Chinese medicine can effectively and safely treating chronic hepatitis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of chronic hepatitis.
Background technology
definition
Chronic hepatitis refers to and is caused by different pathogeny, and the course of disease is at least continued above hepatic necrosis and the inflammation of more than 6 months.Corresponding symptom, sign regulating liver-QI biochemical analysis can be had clinically abnormal, also without obvious clinical symptoms, can only have necrosis and the inflammation of hepatic tissue.The course of disease is undulatory property or lasting Progressive symmetric erythrokeratodermia, and if do not carried out suitable treatment, some patients can be in progress as liver cirrhosis.
etiology and pathogenesis
To coerce the disease that flank one or both sides pain is main manifestations.Under liver occupies the side of body, its passages through which vital energy circulates is distributed in two sides of body, the gallbladder being attached to the liver, and its arteries and veins also follows in the side of body, so hypochondriac pain is how relevant with liver and gall diseases.All depressed emotions, depression of liver-QI, or surfeit delicious food, be addicted to drink immoderate, or weakness due to chronic disease, melancholy,anxiety and overstrain, or tumbling down wound etc. all can cause hypochondriac pain.Time dialectical, should first divide QI and blood deficiency and excess, general stagnation of QI person mostly is distending pain, and sore spot migration is indefinite.Blood stasis person mostly is twinge, localized pain.Deficiency syndrome hypochondriac pain has a dull ache more, and the many pain bursts of excess syndrome hypochondriac pain, pain gesture is more acute.
symptom
The early symptom of classic chronic hepatitis is slight and lack specificity, intermittent in undulatory property, even for many years without any symptom.Modal is exactly easy tired and stomach discomfort, and be easily left in the basket, being also easily mistaken as is gastropathy; Often see invisible liver cirrhosis patient clinically, before there is liver cirrhosis, do not feel significant discomfort, also do not carry out conventional health check-up, progressively developing into liver cirrhosis unconsciously; Occasionally there is patient to occur feeling sick, abdominal distention, jaundice, urine color depth, but the order of severity of chronic hepatitis can not be judged according to symptom.
Medical material present Research involved in the present invention is as follows:
Radix Glehniae [source] this product is the dry root of samphire glehnia littoralis Glehnia littoralis Fr. Schmidt ex Miq..Summer, Qiu Erji excavate, and removing fibrous root, cleans, slightly dry in the air, and put after scalding in boiling water, and removing crust is dry.Or clean convection drying.[nature and flavor] sweet, micro-hardship, is slightly cold.[return through] attaches to the lung and stomach meridians.[function cures mainly] nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.For lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound is thirsty.[usage and dosage] 4.5 ~ 12g.[attention] should not with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using.
The Radix Rehmanniae [source] this product is the fresh or dried root of scrophulariaceae rehmannia glutinosa plant Rehmannia glutinosa Libosch..Autumn excavates, except removing LU, fibrous root and silt, and using fresh herb; Or Radix Rehmanniae is slowly cured to about most probably dry.The former practises title " Radix Rehmanniae ", and the latter practises title " Radix Rehmanniae ".[nature and flavor] are sweet, cold.[return through] GUIXIN, liver, kidney channel.[function cures mainly] Radix Rehmanniae: clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis sends out speckle dermexanthesis.[usage and dosage] 6 ~ 15g.
Radix Polygoni Multiflori Preparata [source] this product is the dried root of polygonum multiflorum thunb Polygonum multiflorum Thunb., and its rattan claims " Caulis Polygoni Multiflori ".Autumn, winter two excavate when season, leaf was withered, two ends of pruning, and clean, individual greatly be cut into block, dry.[nature and flavor] are bitter, sweet, puckery, temperature.[return through] returns liver, the heart, kidney channel.[function cures mainly] detoxifies, eliminating carbuncle, loosening bowel to relieve constipation.For scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; Hyperlipidemia.[usage and dosage] 6 ~ 12g.
Radix Scutellariae [source] this product is the dry root of labiate Radix Scutellariae Scutellaria baicalensis Georgi.Spring, Qiu Erji excavate, and removing fibrous root and silt, hit rough bark after solarization, dry.[nature and flavor] are bitter, cold.[return through] returns lung, gallbladder, spleen, large intestine, small intestine meridian.[function cures mainly] heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.[usage and dosage] 3 ~ 9g.
The Radix Paeoniae Alba [source] this product is the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Summer, Qiu Erji excavate, and clean, and remove end to end and radicula, put in boiling water after boiling rear removing crust or peeling and boil, dry.[nature and flavor] are bitter, sour, are slightly cold.[return through] returns liver, spleen channel.The pain relieving of [function cures mainly] suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.[usage and dosage] 6 ~ 15g.[attention] should not with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using.
Fructus Toosendan [source] this product is the dry mature fruit of Meliaceae plant Fructus Toosendan Melia toosendan Sieb. et Zucc..Gather during fruit maturation in winter, removing impurity, dry.[nature and flavor] are bitter, cold; Slightly poisonous.[return through] returns liver, small intestinal, urinary bladder channel.[function cures mainly] soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.[usage and dosage] 4.5 ~ 9g.
Rhizoma Cyperi [source] this product is the dry rhizome of sedge dried tuber Cyperus rotundus L..Autumn excavates, sing the hair must, put in boiling water after slightly boiling or steaming and dry, or burn and directly to dry afterwards.[nature and flavor] pungent, micro-hardship, micro-sweet, flat.[return through] returns liver, spleen, tri-jiao channel.[function cures mainly] promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.[usage and dosage] 6 ~ 9g.
Fructus Evodiae [source] this product is rutaceae Fructus Evodiae Evodia rutaecarpa(Juss.) Benth., Shi Hu Evodia rutaecarpa(Juss.) the dry almost ripe fruit of Benth. var. officinalis (Dode) Huang or thin hair Fructus Evodiae Evodia rutaecarpa (Juss.) Benth. var. bodinieri (Dode) Huang.When 8 ~ November, fruit not yet ftractureed, cut Fruit branch, dry or cold drying, except impurity such as debranching, leaf, carpopodiums.[nature and flavor] are pungent, bitter, heat; Slightly poisonous.[return through] returns liver, spleen, stomach, kidney channel.[function cures mainly] dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.For headache due to JUE YIN disorder, colic of cold type is suffered from abdominal pain, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, abdominal distention, vomiting acid regurgitation, Diarrhoea, external treatment aphtha; Hypertension.[usage and dosage] 1.5 ~ 6g; Suitable amount used externally.
The dry mature fruit that smallage [source] is samphire smallage.[nature and flavor] three grades are xeothermic, bitter in the mouth.[function cures mainly] raw dry heat-dissipating, cold relieving diuresis, loose gas pain relieving, dampness is whetted the appetite, and stimulates the menstrual flow in warm palace.Cure mainly raw property or lymphatic temperament disease, as cold dysuria, depressed property stomachache, abdominal distention, hypochondriac pain, moist dyspepsia, anorexia, irregular menstruation etc.[each discussion] " health care herbal garden buy He Zini ": " logical resistance appetizing, eliminates yellow cellulitis, tonneau urine, calculus dissolving and excreting, pleasantly relievings asthma, hypersexuality, warming the liver pain relieving, dispelling wind for relieving itching, removing toxic substances, wind-expelling pain-stopping, and speckle dispelling blazes; Control food stagnation not receive, yellow cellulitis, urine difficulty, various calculus, asthma is panted, and hyposexuality, cold liver pain, eczema, skin rash is itched, alimentary toxicosis, sciatica, butterfly spot, white paralysed wind etc." " garden of medicine ": " eliminate viscous liquid, loose gas de-swelling, induced abortion, energy cold-proof drug intoxication etc.; Control conspicuous property liquid in body to increase, depressed in abdomen, retention of dead fetus, cold drug intoxication etc. ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of chronic hepatitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing chronic hepatitis.
In order to achieve the above object, the present invention is by the following technical solutions: a kind of Chinese medicine being used for the treatment of chronic hepatitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix Glehniae 10 parts, 8 parts, the Radix Rehmanniae, Radix Polygoni Multiflori Preparata 9 parts, Radix Scutellariae (parched) 6 parts, Radix Paeoniae Alba (parched) 9 parts, Fructus Toosendan 6 parts, Rhizoma Cyperi (processed) 6 parts, Fructus Evodiae 6 parts, smallage 6 parts.
Inventor thinks depression of liver-QI, qi depression to blood stasis, and then yang-energy of long duration is deficient, and the unable promotion blood operation of the deficiency of vital energy, blocks in two sides of body, sends out as hypochondriac pain.Therefore assembly is our.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects outpatient service for 2012 and chronic hepatitis patient 68 example of being in hospital altogether between year December of April ~ 2012, be divided into treatment group 34 example and matched group 34 example at random, treatment group man 24 example, female 10 example, 22 ~ 55 years old age, 48.4 years old mean age, the course of disease 5 ~ 25 years; Matched group man 26 example, female 8 example, 23 ~ 49 years old age, 46.7 years old mean age, the course of disease 4 ~ 23 years.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 2 times.3 months courses for the treatment of.
The oral Oxymatrine Capsule of matched group (the accurate word H20020044 of traditional Chinese medicines, Ningxia Boertaili Pharmaceutical Co., Ltd), takes according to its description.1 month course for the treatment of.
3, therapeutic outcome
Criterion of therapeutical effect
Recovery from illness: clinical symptoms disappears substantially, and lab testing ALT, AST, TP all recover normal, and A/G is inverted correction; Effective: clinical symptom remission, lab testing is improved; Invalid: clinical symptoms and lab testing are without being clearly better.
Therapeutic outcome is in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Effectively | Invalid | Total effective rate (%) | Total cure rate (%) |
| Treatment group | 34 | 12 | 21 | 1 | 97.0% * | 35.3% * |
| Matched group | 34 | 6 | 22 | 6 | 82.4% | 17.6% |
Compare with matched group,
*p<0.05.
Visible, the medicine that the present invention obtains can safe and effective treatment chronic hepatitis, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Radix Glehniae 10 grams, 8 grams, the Radix Rehmanniae, Radix Polygoni Multiflori Preparata 9 grams, Radix Scutellariae (parched) 6 grams, Radix Paeoniae Alba (parched) 9 grams, Fructus Toosendan 6 grams, Rhizoma Cyperi (processed) 6 grams, Fructus Evodiae 6 grams, smallage 6 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of chronic hepatitis.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: Radix Glehniae 10 grams, 8 grams, the Radix Rehmanniae, Radix Polygoni Multiflori Preparata 9 grams, Radix Scutellariae (parched) 6 grams, Radix Paeoniae Alba (parched) 9 grams, Fructus Toosendan 6 grams, Rhizoma Cyperi (processed) 6 grams, Fructus Evodiae 6 grams, smallage 6 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of chronic hepatitis.Oral, daily once.
Specific embodiment 3
Take: Radix Glehniae 10 grams, 8 grams, the Radix Rehmanniae, Radix Polygoni Multiflori Preparata 9 grams, Radix Scutellariae (parched) 6 grams, Radix Paeoniae Alba (parched) 9 grams, Fructus Toosendan 6 grams, Rhizoma Cyperi (processed) 6 grams, Fructus Evodiae 6 grams, smallage 6 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of chronic hepatitis.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. one kind is used for the treatment of the Chinese medicine of chronic hepatitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix Glehniae 10 parts, 8 parts, the Radix Rehmanniae, Radix Polygoni Multiflori Preparata 9 parts, Radix Scutellariae (parched) 6 parts, Radix Paeoniae Alba (parched) 9 parts, Fructus Toosendan 6 parts, Rhizoma Cyperi (processed) 6 parts, Fructus Evodiae 6 parts, smallage 6 parts.
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| CN201410757206.9A CN104383199A (en) | 2014-12-11 | 2014-12-11 | Traditional Chinese medicine used for treating chronic hepatitis |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20040079724A (en) * | 2003-03-10 | 2004-09-16 | 주식회사 생그린 | Mixed herbal extract for chronic hepatitis remedy |
| CN1843456A (en) * | 2005-04-07 | 2006-10-11 | 孙毅 | Method for extracting polysaccharide from Chinese formula of 'Yi Guan Jian' |
-
2014
- 2014-12-11 CN CN201410757206.9A patent/CN104383199A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20040079724A (en) * | 2003-03-10 | 2004-09-16 | 주식회사 생그린 | Mixed herbal extract for chronic hepatitis remedy |
| CN1843456A (en) * | 2005-04-07 | 2006-10-11 | 孙毅 | Method for extracting polysaccharide from Chinese formula of 'Yi Guan Jian' |
Non-Patent Citations (4)
| Title |
|---|
| 尹书红 等: "一贯煎加味治疗肝肾阴虚型慢性乙型肝炎100例", 《北京中医药大学学报（中医临床版）》 * |
| 李启德: "《学得会的中医治病》", 31 January 2014 * |
| 毛顺卿: "《中医肝胆病辨治精要》", 30 November 2013 * |
| 范哲平: "一贯煎加减治疗慢性肝炎99例", 《河南中医》 * |
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