CN104383096A - Hemorrhoid relieving tablet composition and preparation method thereof - Google Patents
Hemorrhoid relieving tablet composition and preparation method thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract
The invention relates to the field of drugs and particularly relates to a hemorrhoid relieving tablet composition and a preparation method thereof. The hemorrhoid relieving tablet composition is prepared from the twelve natural raw materials including carbonized sanguisorba roots, carbonized cacumen platycladi, rhizoma rehmanniae, sophora japonica, radix paeoniae alba, carbonized schizonepeta, angelica sinensis, radix scutellariae, fructus aurantii, hedgehog hides, dark plums and liquorice by using a special preparation method comprising the steps of distilling, decocting, concentrating and filtering. The hemorrhoid relieving tablet composition has the effects of removing heat to cool blood as well as moistening and dispelling wind, has a remarkable effect for relieving symptoms such as hemorrhoidal bleeding, swelling and the like caused by internal excessive heat accumulation or dampness-heat stasis and is rapid in taking effects and capable of effectively relieving the burden and pain of a patient and ensuring that hemorrhoid does not easily recur; and the adopted raw materials are wide in source, low in cost and free of remarkable toxic or side effect.
Description
Technical field
The invention relates to drug world, is specifically related to a kind of ZHINING PIAN composition and method of making the same.
Background technology
Hemorrhoid are the distinctive commonly encountered diseases of the mankind, frequently-occurring disease, hemorrhoid have multiple reasons: or because of eating and drinking without temperance, surfeit is pungent, indulgence in drinking and sexsual activity, so that caused by damp invasion of lower energizer large intestine; Or because of chronic diarrhea chronic dysentery, sitting standing for a long time, bears stool for a long time, forepart pregnant women and cause disorder of YIN and YANG, obstruction and rejection swelling plug, passages through which vital energy circulates slime flux, between leaky intestine, so that punching is sent out as hemorrhoid; Or because of affection of exogenous wind-cold heat-damp in summer dryness-fire, caused by bet anus; Or because of internal damage by the excessive seven emotions, pyretic toxicity temperature is amassed, QI and blood swelling dysentery falls, blockage of main and collateral channels and the stagnant knot of the stasis of blood gathers in anus, so that conflict is hemorrhoid.Make a general survey of above-mentioned reason, for modern, then is mostly that transconversion into heat is dry humorously by raw in the factors such as damp and hot inner product, the sitting standing for a long time pungent without joint, surfeit of drinking so that body, is damp and hotly detained, under foul smell blood stasis bet anus causes rectum lower end mucosa and the subcutaneous hemorrhoidal plexus varicose of anal canal and being formed.
Current treatment hemorrhoid many employings doctor trained in Western medicine, Western medicine, doctor trained in Western medicine then more adopts the therapies such as operation, ligation, injection, has because recurring that Repeated Operation causes fistula, What is more moves anal sphincter bad, causes great misery to patient, can only cure the symptoms, not the disease, effectively can not effect a radical cure hemorrhoid.Western medicine then take effect after medication slow, poor effect, can not effect a radical cure, equally usually recurrent exerbation, have a strong impact on the quality of worklife and physical and mental health.
On the other hand, utilize the medicine of Chinese herbal treatment hemorrhoid also to get more and more gradually, have for oral administration, external, but therapeutic effect is mostly not satisfactory.As Pilulae Fructus Sophorae, the Radix Sanguisorbae Fructus Sophorae, the analgesic effect of these medicines is also not obvious, even within 3 ~ 5 days, does not subside a swelling, and two weeks blood stasis can not come off disappearance, and within one month, internal hemorrhoid can not heal.
Summary of the invention
The object of the invention is to avoid above-mentioned weak point of the prior art and provides that a kind of effect is good, the ZHINING PIAN composition and method of making the same of instant effect.
The object of the invention is achieved through the following technical solutions:
Provide a kind of ZHINING PIAN compositions, its composition of raw materials is: charred Radix Sanguisorbae 386.2-415.9g, Platycladi Cacumen carbonisatum 386.2-415.9g, Radix Rehmanniae 285.2-314.9g, Flos Sophorae Immaturus 264.4-294.1g, Radix Paeoniae Alba 264.4-294.1g, Herba Schizonepetae charcoal 151.5-181.2g, Radix Angelicae Sinensis 264.4-294.1g, Radix Scutellariae 264.4-294.1g, Fructus Aurantii 151.5-181.2g, Corium Erinacei Seu Hemiechianus 151.5-181.2g, Fructus Mume 151.5-181.2g, Radix Glycyrrhizae 68.6-98.3g.
The preparation method of this ZHINING PIAN compositions is: get all the above-mentioned 12 taste raw materials ready according to above-mentioned composition of raw materials; Get Radix Angelicae Sinensis and this two tastes raw material of Fructus Aurantii carries out distillating extracting oil with for subsequent use, the another extracting container of the aqueous solution after distillation is collected; Medicinal residues after distillation and other ten taste raw materials decoct with water twice, each 3 hours, collecting decoction, filter, when being evaporated to 80 DEG C after being merged by the aqueous solution that another extracting container after the filtrate of decoction and distillation is collected, relative density is the clear paste of 1.30-1.35, after cold drying, pulverized granulation, then spray into above-mentioned volatile oil, tabletting film coating, to obtain final product.
Its each raw material of this ZHINING PIAN compositions preferably component is: charred Radix Sanguisorbae 400g, Platycladi Cacumen carbonisatum 400g, Radix Rehmanniae 300g, Flos Sophorae Immaturus 280g, Radix Paeoniae Alba 280g, Herba Schizonepetae charcoal 166.8g, Radix Angelicae Sinensis 280g, Radix Scutellariae 280g, Fructus Aurantii 166.8g, Corium Erinacei Seu Hemiechianus 166.8g, Fructus Mume 166.8g, Radix Glycyrrhizae 83.4g.
The beneficial effect of the invention:
The ZHINING PIAN compositions of the invention adopts 12 taste natural materials to form via preparation method special specially configuration.Comprising the charred Radix Sanguisorbae with cooling blood for hemostasis, the effect of removing toxic substances sore, obviously can shorten the Platycladi Cacumen carbonisatum of bleeding time and clotting time, there is the Radix Rehmanniae of phencyclidine effect, the Flos Sophorae Immaturus of cooling blood for hemostasis, purging liver-fire, the Radix Paeoniae Alba of blood-supplementing blood-nourishing, treatment is had blood in stool, the Herba Schizonepetae charcoal of metrorrhagia, the Radix Angelicae Sinensis of enrich blood, invigorating blood circulation, keeping tensions down, uneasy Radix Scutellariae effectively, the Fructus Aurantii of dispelling the stagnated QI, row expectorant, removing food stagnancy, cure mainly have blood in stool, the Corium Erinacei Seu Hemiechianus of hemorrhoid, the Fructus Mume promote the production of body fluid, purified the blood, is used for the treatment of the Radix Glycyrrhizae of insufficiency of heart-QI, irregularly intermittent and regularly intermittent pulse.The ZHINING PIAN compositions energy clearing away heat and cooling blood made, moisturize dispelling wind, the symptom such as be used for the treatment of knot or the bleeding hemorrhoids caused by damp and hot stasis in excess-heat, swell and ache, Be very effective, and instant effect, not easily to recur, the raw material sources adopted are wide, cost is low, without obvious toxic-side effects, can effectively relieve patient ' s burden and slight illness.And the method technique that it is prepared is simple, extraction efficiency is high, energy consumption and loss little, cost is low, is beneficial to penetration and promotion application.
Detailed description of the invention
With the following Examples the invention is further described.
A kind of ZHINING PIAN compositions of the invention, adopts charred Radix Sanguisorbae, Platycladi Cacumen carbonisatum, Radix Rehmanniae, the Flos Sophorae Immaturus, Radix Paeoniae Alba, Herba Schizonepetae charcoal, Radix Angelicae Sinensis, Radix Scutellariae, Fructus Aurantii, Corium Erinacei Seu Hemiechianus, Fructus Mume, and the configuration of Radix Glycyrrhizae 12 taste natural material forms.Wherein, the consumption of each raw material is equipped with according to following composition of raw materials: charred Radix Sanguisorbae 386.2-415.9g, Platycladi Cacumen carbonisatum 386.2-415.9g, Radix Rehmanniae 285.2-314.9g, Flos Sophorae Immaturus 264.4-294.1g, Radix Paeoniae Alba 264.4-294.1g, Herba Schizonepetae charcoal 151.5-181.2g, Radix Angelicae Sinensis 264.4-294.1g, Radix Scutellariae 264.4-294.1g, Fructus Aurantii 151.5-181.2g, Corium Erinacei Seu Hemiechianus 151.5-181.2g, Fructus Mume 151.5-181.2g, Radix Glycyrrhizae 68.6-98.3g.
Preferably, the preferably composition of raw materials through experimental verification is: charred Radix Sanguisorbae 400g, Platycladi Cacumen carbonisatum 400g, Radix Rehmanniae 300g, Flos Sophorae Immaturus 280g, Radix Paeoniae Alba 280g, Herba Schizonepetae charcoal 166.8g, Radix Angelicae Sinensis 280g, Radix Scutellariae 280g, Fructus Aurantii 166.8g, Corium Erinacei Seu Hemiechianus 166.8g, Fructus Mume 166.8g, Radix Glycyrrhizae 83.4g.
Concrete preparation:
After getting all the above-mentioned 12 taste raw materials ready according to composition of raw materials, first get Radix Angelicae Sinensis and this two tastes raw material of Fructus Aurantii carries out distillating extracting oil, the volatile oil of extraction is collected for subsequent use, and the same another extracting container of the aqueous solution after distillation is collected.
Subsequently, the medicinal residues after distillation are merged with other ten taste raw materials together with decoct with water twice, each 3 hours, collecting decoction, filter, merged by the aqueous solution that rear to the filtrate of decoction and distillation another extracting container is collected, when being concentrated into 80 DEG C by reducing pressure after filtering, relative density is the clear paste of 1.30-1.35, adopt the form of cold drying after its drying, pulverized and made granular, then sprayed into above-mentioned volatile oil to it, last tabletting, make 1000, then film coating completes preparation.
This ZHINING PIAN compositions is Film coated tablets, aobvious pitchy after removing film-coat, and the micro-acid of bitter in the mouth, adopts oral way, within 1st, take 3 times, each 3 ~ 4, and avoid pungent food during taking food.
Finally should be noted that; above embodiment is only in order to illustrate the technical scheme of the invention; but not the restriction to the invention protection domain; although done to explain to the invention with reference to preferred embodiment; those of ordinary skill in the art is to be understood that; can modify to the technical scheme of the invention or equivalent replacement, and not depart from essence and the scope of the invention technical scheme.
Claims (3)
1. a ZHINING PIAN compositions, is characterized in that its composition of raw materials is: charred Radix Sanguisorbae 386.2-415.9g, Platycladi Cacumen carbonisatum 386.2-415.9g, Radix Rehmanniae 285.2-314.9g, Flos Sophorae Immaturus 264.4-294.1g, Radix Paeoniae Alba 264.4-294.1g, Herba Schizonepetae charcoal 151.5-181.2g, Radix Angelicae Sinensis 264.4-294.1g, Radix Scutellariae 264.4-294.1g, Fructus Aurantii 151.5-181.2g, Corium Erinacei Seu Hemiechianus 151.5-181.2g, Fructus Mume 151.5-181.2g, Radix Glycyrrhizae 68.6-98.3g.
2. a kind of ZHINING PIAN compositions according to claim 1, is characterized in that its composition of raw materials is: charred Radix Sanguisorbae 400g, Platycladi Cacumen carbonisatum 400g, Radix Rehmanniae 300g, Flos Sophorae Immaturus 280g, Radix Paeoniae Alba 280g, Herba Schizonepetae charcoal 166.8g, Radix Angelicae Sinensis 280g, Radix Scutellariae 280g, Fructus Aurantii 166.8g, Corium Erinacei Seu Hemiechianus 166.8g, Fructus Mume 166.8g, Radix Glycyrrhizae 83.4g.
3. a preparation method for ZHINING PIAN compositions, is characterized in that comprising the following steps: get all this 12 taste raw material ready according to the composition of raw materials that claim 1 or 2 provides; Get Radix Angelicae Sinensis and this two tastes raw material of Fructus Aurantii carries out distillating extracting oil with for subsequent use, the another extracting container of the aqueous solution after distillation is collected; Medicinal residues after distillation and other ten taste raw materials decoct with water twice, each 3 hours, collecting decoction, filter, when being evaporated to 80 DEG C after being merged by the aqueous solution that another extracting container after the filtrate of decoction and distillation is collected, relative density is the clear paste of 1.30-1.35, after cold drying, pulverized granulation, then spray into above-mentioned volatile oil, tabletting film coating, to obtain final product.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104958694A (en) * | 2015-06-18 | 2015-10-07 | 许五妮 | Traditional Chinese medicine preparation for treating internal hemorrhoids with bleeding |
CN105770704A (en) * | 2016-04-29 | 2016-07-20 | 覃佳林 | Traditional Chinese medicine preparation for treating hemorrhoids and preparation method thereof |
CN111693630A (en) * | 2020-07-16 | 2020-09-22 | 华润三九(郴州)制药有限公司 | Construction method and application of hemorrhoid treating tablet HPLC standard fingerprint |
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CN1247075A (en) * | 1998-09-09 | 2000-03-15 | 王奉炳 | Chinese patent medicine for treating piles |
CN1589860A (en) * | 2003-08-27 | 2005-03-09 | 陈帮映 | Chinese medicinal composition for treating hemorrhoid |
CN1634283A (en) * | 2004-11-24 | 2005-07-06 | 韩喜 | Chinese traditional medicine for treating hemorrhoid bloody stool |
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2014
- 2014-11-25 CN CN201410690773.7A patent/CN104383096A/en active Pending
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CN1247075A (en) * | 1998-09-09 | 2000-03-15 | 王奉炳 | Chinese patent medicine for treating piles |
CN1589860A (en) * | 2003-08-27 | 2005-03-09 | 陈帮映 | Chinese medicinal composition for treating hemorrhoid |
CN1634283A (en) * | 2004-11-24 | 2005-07-06 | 韩喜 | Chinese traditional medicine for treating hemorrhoid bloody stool |
Non-Patent Citations (1)
Title |
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国家药典委员会: "《中华人民共和国药典 2010年版 一部》", 31 December 2010, 中国医药科技出版社 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104958694A (en) * | 2015-06-18 | 2015-10-07 | 许五妮 | Traditional Chinese medicine preparation for treating internal hemorrhoids with bleeding |
CN105770704A (en) * | 2016-04-29 | 2016-07-20 | 覃佳林 | Traditional Chinese medicine preparation for treating hemorrhoids and preparation method thereof |
CN111693630A (en) * | 2020-07-16 | 2020-09-22 | 华润三九(郴州)制药有限公司 | Construction method and application of hemorrhoid treating tablet HPLC standard fingerprint |
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