CN104379157A - 使用葡萄籽提取物调节氧化应激、炎症和胰岛素敏感度降低 - Google Patents

使用葡萄籽提取物调节氧化应激、炎症和胰岛素敏感度降低 Download PDF

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Publication number
CN104379157A
CN104379157A CN201380026503.XA CN201380026503A CN104379157A CN 104379157 A CN104379157 A CN 104379157A CN 201380026503 A CN201380026503 A CN 201380026503A CN 104379157 A CN104379157 A CN 104379157A
Authority
CN
China
Prior art keywords
grape seed
seed extract
subject
oxidative stress
inflammation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380026503.XA
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English (en)
Chinese (zh)
Inventor
C·卡帕哥达
B·伯顿弗里曼
I·艾迪瑞辛格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Publication of CN104379157A publication Critical patent/CN104379157A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201380026503.XA 2012-04-10 2013-04-10 使用葡萄籽提取物调节氧化应激、炎症和胰岛素敏感度降低 Pending CN104379157A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261622339P 2012-04-10 2012-04-10
US61/622,339 2012-04-10
US13/841,673 US20140023737A1 (en) 2012-04-10 2013-03-15 Modulation of Oxidative Stress, Inflammation, and Impaired Insulin Sensitivity with Grape seed Extract
US13/841,673 2013-03-15
PCT/US2013/035944 WO2013155166A1 (en) 2012-04-10 2013-04-10 Modulation of oxidative stress, inflammation, and impaired insulin sensitivity with grape seed extract

Publications (1)

Publication Number Publication Date
CN104379157A true CN104379157A (zh) 2015-02-25

Family

ID=49328123

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380026503.XA Pending CN104379157A (zh) 2012-04-10 2013-04-10 使用葡萄籽提取物调节氧化应激、炎症和胰岛素敏感度降低

Country Status (5)

Country Link
US (3) US20140023737A1 (enExample)
EP (1) EP2836225A4 (enExample)
CN (1) CN104379157A (enExample)
IN (1) IN2014DN09383A (enExample)
WO (1) WO2013155166A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107920561A (zh) * 2015-03-16 2018-04-17 自然阳光产品公司 可用于食品、饮食补充剂、化妆品和药物制剂的呈现多种协同抗氧化剂活性的植物复合物
CN116801873A (zh) * 2020-09-29 2023-09-22 艾克瑅夫因赛德 包含黄烷醇单体和e-葡萄素的组合物

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7296189B2 (ja) 2016-07-22 2023-06-22 株式会社エーゼット ブドウ種子抽出物を含む更年期障害改善剤
JP7279943B2 (ja) * 2020-07-03 2023-05-23 株式会社エーゼット ブドウ種子抽出物を含む更年期障害改善剤

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101511208A (zh) * 2005-09-28 2009-08-19 加利福尼亚大学董事会 用于在高血压前期个体和/或患有代谢综合征的个体中降低血压的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544581B1 (en) * 1999-06-22 2003-04-08 Canandaigua Wine Company, Inc. Process for extraction, purification and enrichment of polyphenolic substances from whole grapes, grape seeds and grape pomace
WO2007038685A2 (en) * 2005-09-28 2007-04-05 Constellation Brands, Inc. Grape extract, dietary supplement thereof, and processes therefor

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101511208A (zh) * 2005-09-28 2009-08-19 加利福尼亚大学董事会 用于在高血压前期个体和/或患有代谢综合征的个体中降低血压的方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ALANM.RULIS: ""SUMMARY OF DATA FOR CHEMICAL SELECTION"", 《GRAS NOTICE 000093》 *
WANNAPORN SUWANNAPHET，等: ""Preventive effect of grape seed extract against high-fructose diet-induced insulin resistance and oxidative stress in rats"", 《食品与化学毒性》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107920561A (zh) * 2015-03-16 2018-04-17 自然阳光产品公司 可用于食品、饮食补充剂、化妆品和药物制剂的呈现多种协同抗氧化剂活性的植物复合物
US11331363B2 (en) 2015-03-16 2022-05-17 Nature's Sunshine Products, Inc. Phytocomplexes exhibiting multiple, synergistic antioxidant activities useful in foods, dietary supplements, cosmetics and pharmaceutical preparations
CN116801873A (zh) * 2020-09-29 2023-09-22 艾克瑅夫因赛德 包含黄烷醇单体和e-葡萄素的组合物

Also Published As

Publication number Publication date
EP2836225A1 (en) 2015-02-18
US20150258160A1 (en) 2015-09-17
IN2014DN09383A (enExample) 2015-07-17
US20140023737A1 (en) 2014-01-23
US20150258159A1 (en) 2015-09-17
EP2836225A4 (en) 2015-11-04
WO2013155166A1 (en) 2013-10-17

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