IN2014DN09383A - - Google Patents

Info

Publication number
IN2014DN09383A
IN2014DN09383A IN9383DEN2014A IN2014DN09383A IN 2014DN09383 A IN2014DN09383 A IN 2014DN09383A IN 9383DEN2014 A IN9383DEN2014 A IN 9383DEN2014A IN 2014DN09383 A IN2014DN09383 A IN 2014DN09383A
Authority
IN
India
Prior art keywords
grape seed
seed extract
anthocyanidins
inflammation
oxidative stress
Prior art date
Application number
Inventor
Chulani Kappagoda
Britt Burton-Freeman
Indika Edirisingue
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of IN2014DN09383A publication Critical patent/IN2014DN09383A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Method for modulating oxidative stress, inflammation, and impaired insulin sensitivity in a subject by using a grape seed extract, the method being useful in modulating post- prandial oxidative stress, inflammation and impaired insulin sensitivity in patients suffering from Metabolic Syndrome (MetS). The method comprising administering a therapeutically effective amount of a grape seed extract and a pharmaceutically acceptable excipient. The grape seed extract is a polyphenolic extract comprising pro anthocyanidins and anthocyanidins.
IN9383DEN2014 2012-04-10 2013-04-10 IN2014DN09383A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261622339P 2012-04-10 2012-04-10
US13/841,673 US20140023737A1 (en) 2012-04-10 2013-03-15 Modulation of Oxidative Stress, Inflammation, and Impaired Insulin Sensitivity with Grape seed Extract
PCT/US2013/035944 WO2013155166A1 (en) 2012-04-10 2013-04-10 Modulation of oxidative stress, inflammation, and impaired insulin sensitivity with grape seed extract

Publications (1)

Publication Number Publication Date
IN2014DN09383A true IN2014DN09383A (en) 2015-07-17

Family

ID=49328123

Family Applications (1)

Application Number Title Priority Date Filing Date
IN9383DEN2014 IN2014DN09383A (en) 2012-04-10 2013-04-10

Country Status (5)

Country Link
US (3) US20140023737A1 (en)
EP (1) EP2836225A4 (en)
CN (1) CN104379157A (en)
IN (1) IN2014DN09383A (en)
WO (1) WO2013155166A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10434131B2 (en) 2015-03-16 2019-10-08 Nature's Sunshine Products, Inc. Phytocomplexes exhibiting multiple, synergistic antioxidant activities useful in foods, dietary supplements, cosmetics and pharmaceutical preparations
JP7296189B2 (en) 2016-07-22 2023-06-22 株式会社エーゼット Menopause improving agent containing grape seed extract
JP7279943B2 (en) * 2020-07-03 2023-05-23 株式会社エーゼット Menopause improving agent containing grape seed extract
FR3114497B1 (en) * 2020-09-29 2023-06-02 Activinside Composition comprising flavanol monomers and ε-viniferin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544581B1 (en) * 1999-06-22 2003-04-08 Canandaigua Wine Company, Inc. Process for extraction, purification and enrichment of polyphenolic substances from whole grapes, grape seeds and grape pomace
JP5424641B2 (en) * 2005-09-28 2014-02-26 コンステレーション・ブランズ・インコーポレーテッド Grape extract, its dietary supplement, and method
NZ567332A (en) * 2005-09-28 2011-05-27 Univ California Method for lowering blood pressure in pre-hypertensive individuals and/or individuals with metabolic syndrome

Also Published As

Publication number Publication date
WO2013155166A1 (en) 2013-10-17
EP2836225A1 (en) 2015-02-18
US20150258159A1 (en) 2015-09-17
CN104379157A (en) 2015-02-25
US20140023737A1 (en) 2014-01-23
EP2836225A4 (en) 2015-11-04
US20150258160A1 (en) 2015-09-17

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