CN104372093B - 一种基于高通量测序的snp检测方法 - Google Patents

一种基于高通量测序的snp检测方法 Download PDF

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CN104372093B
CN104372093B CN201410643497.9A CN201410643497A CN104372093B CN 104372093 B CN104372093 B CN 104372093B CN 201410643497 A CN201410643497 A CN 201410643497A CN 104372093 B CN104372093 B CN 104372093B
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sequence
probe
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detection probe
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CN104372093A (zh
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王栋
王辉
张岩
项光新
孙义民
邢婉丽
程京
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Tsinghua University
CapitalBio Corp
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CapitalBio Corp
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Priority to US15/525,037 priority patent/US10704092B2/en
Priority to PCT/CN2015/000784 priority patent/WO2016074338A1/en
Priority to JP2017525077A priority patent/JP6684790B2/ja
Priority to EP15859614.8A priority patent/EP3218522B1/en
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CN201410643497.9A CN104372093B (zh) 2014-11-10 2014-11-10 一种基于高通量测序的snp检测方法
US15/525,037 US10704092B2 (en) 2014-11-10 2015-11-10 Detection methods based on sequencing
PCT/CN2015/000784 WO2016074338A1 (en) 2014-11-10 2015-11-10 Detection methods based on sequencing
JP2017525077A JP6684790B2 (ja) 2014-11-10 2015-11-10 シーケンスに基づく検出方法
EP15859614.8A EP3218522B1 (en) 2014-11-10 2015-11-10 Detection methods based on sequencing

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US10829816B2 (en) 2012-11-19 2020-11-10 Apton Biosystems, Inc. Methods of analyte detection
CA2891939C (en) 2012-11-19 2020-10-27 Apton Biosystems, Inc. Digital analysis of molecular analytes using single molecule detection
CN104372093B (zh) * 2014-11-10 2016-09-21 博奥生物集团有限公司 一种基于高通量测序的snp检测方法
CN105177160B (zh) * 2015-10-16 2018-10-16 浙江大学 检测多种新生儿遗传代谢病致病基因的引物及试剂盒
CN105506120B (zh) * 2016-01-05 2019-10-18 石玉玲 线粒体突变性耳聋的多重Taqman荧光检测试剂盒
CN105734130B (zh) * 2016-03-11 2019-10-25 中国农业科学院生物技术研究所 全基因组范围的植物基因功能鉴定的方法
CN114921537A (zh) 2017-03-17 2022-08-19 雅普顿生物系统公司 测序和高分辨率成像
EP3601599A4 (en) * 2017-03-23 2020-12-23 Apton Biosystems, Inc. POLYMORPHISM DETECTION WITH INCREASED ACCURACY
CN107119122B (zh) * 2017-05-08 2020-07-07 苏州先达基因科技有限公司 一种单核苷酸多态性检测用试剂盒及检测方法
CN108018344A (zh) * 2017-12-22 2018-05-11 美因健康科技（北京）有限公司 基于MLPA+Seq的高通量测序的肿瘤检测方法
WO2020061237A1 (en) 2018-09-19 2020-03-26 Apton Biosystems, Inc. Densely-packed analyte layers and detection methods
CN111379032B (zh) * 2018-12-28 2024-07-23 北京贝瑞和康生物技术有限公司 一种用于构建同时实现基因组拷贝数变异检测和基因突变检测的测序文库的方法和试剂盒
CN110379465A (zh) * 2019-07-19 2019-10-25 元码基因科技（北京）股份有限公司 基于rna靶向测序和机器学习的癌症组织溯源方法
CN112301430B (zh) * 2019-07-30 2022-05-17 北京泛生子基因科技有限公司 一种建库方法及应用
CN111549107B (zh) * 2020-06-10 2021-08-31 华中农业大学 一种利用高通量测序进行基因分型的方法、试剂盒及应用
CN114317748B (zh) * 2021-12-28 2023-09-29 江苏先声医学诊断有限公司 一种基于ddPCR的AML微小残留病变监测方法、试剂盒及其应用
CN114774553A (zh) * 2022-06-01 2022-07-22 上海君远生物科技有限公司 一种利用高通量测序技术检测多基因位点突变的方法

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US10704092B2 (en) 2020-07-07
CN104372093A (zh) 2015-02-25
JP6684790B2 (ja) 2020-04-22
EP3218522A4 (en) 2018-06-13
US20190085393A1 (en) 2019-03-21
WO2016074338A1 (en) 2016-05-19
EP3218522B1 (en) 2020-02-26
JP2017532980A (ja) 2017-11-09
EP3218522A1 (en) 2017-09-20

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