CN104367925A - Traditional Chinese medicine lotion for treating erythroderma and preparation method thereof - Google Patents

Traditional Chinese medicine lotion for treating erythroderma and preparation method thereof Download PDF

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CN104367925A
CN104367925A CN201410620697.2A CN201410620697A CN104367925A CN 104367925 A CN104367925 A CN 104367925A CN 201410620697 A CN201410620697 A CN 201410620697A CN 104367925 A CN104367925 A CN 104367925A
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parts
radix
erythroderma
fructus
rhizoma
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郗艳荣
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JINAN GAODA INFORMATION TECHNOLOGY Co Ltd
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JINAN GAODA INFORMATION TECHNOLOGY Co Ltd
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Abstract

The invention provides a traditional Chinese medicine lotion for treating erythroderma and a preparation method thereof. The lotion is prepared from the following raw materials: American ginseng, polygonatum odoratum, mirabilite, licorice root, rhinoceros horn, notarchus powder, black bean coat, grass-leaved eria, yam, dictamni cortex, radix ophiopogonis, camptotheca acuminata, polygonatum kingianum, coptis chinensis, schisandra chinensis, raw radix rehmanniae, Chinese lizardtail rhizome, carex baccans, fructus amomi, phaenosperma globosa, brackish-water crab, aeschynomene indica and cassia twig. The lotion has the beneficial effects of clearing heat, cooling blood, removing toxicity, inducing diuresis, quickly and effectively improving and controlling attack and spreading of erythroderma, can be used for curing erythroderma. Furthermore, the traditional Chinese medicine lotion is capable of tonifying qi, nourishing blood, nourishing yin and dryness, enhancing patient resistance and improving constitution, is convenient and safe to use, does not have toxic or side effect, and is suitable for long-time taking of patients.

Description

A kind of Chinese medicine lotion for the treatment of erythroderma and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, specifically a kind of Chinese medicine lotion for the treatment of erythroderma and preparation method thereof.
Background technology
Erythroderma also known as exfoliative dermatitis, be a kind of involve whole body with diffusivity flushing, a large amount of desquamation of persistence is that main serious symptom chronic inflammatory skin is sick.Erythroderma is divided into acute and chronic amphitypy.The typical performance of erythroderma is the diffuse flushing of whole skin, infiltration, swelling, desquamation, skin lesion area of getting involved reaches more than 80% of whole skin, but erythroderma not only shows skin, mucosa, skin appendages, lymph node even internal organs are all got involved.Concrete Symptoms is: the mucoprotein deposition of hepatosplenomegaly, low grade fever, skin, liver enlargement, hypotension.Therefore say, erythroderma is not only skin change, and it can involve multiple internal organs, very harmful to patient.
Erythroderma diagnosis is not difficult, the main searching erythroderma cause of disease.Want detailed medical history-taking, carry out a medical examination comprehensive system, often therefrom can find the clue of primary disease, want long term follow-up to observe to the partly cause person of failing to understand.The cause of disease of erythroderma may be relevant to drug allergy, the further developing of some inflammatory dermatoses, malignant tumor etc., also has agnogenio.Erythroderma is a kind of serious dermatosis, and break with tremendous force, mortality rate is up to 10% ~ 20%.
At present, western medical treatment, according to the different causes of disease, adopts and supplements protein, water, electrolyte, injection hormone, the method such as immunosuppressant, hydryllin.But these methods are cured the symptoms, not the disease, and not only erythroderma easily recurs, and the drug side effect such as hormone is large, unsuitable life-time service.
The traditional Chinese medical science is thought, erythroderma system heart-fire is flourishing, and diseases caused by exogenous pathogenic factor poison is evil, scorchingly hot enter blood battalion, and cause QI and blood deficiency, burn body fluid, failure of skin and muscle to be nourished and causing.Or eat taboo, malicious heresy enters internal organs skin and falls ill.
Summary of the invention
The defect of invention in order to make up prior art, provides a kind of evident in efficacy, Chinese medicine lotion of the treatment erythroderma had no side effect and preparation method thereof.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine lotion for erythroderma, it is characterized in that being made up of the herbal raw material of following weight portion:
Radix Panacis Quinquefolii 5 ~ 15 parts, Rhizoma Polygonati Odorati 2 ~ 10 parts, 6 ~ 9 parts, Natrii Sulfas, 9 ~ 20 parts, Radix Glycyrrhizae, Cornu rhinocerotis 1.5 ~ 3 parts, ove Notarchi 1 ~ 3 part, Testa sojae atricolor 3 ~ 9 parts, Herba Eriae Graminifoliae 1 ~ 3 part, Rhizoma Dioscoreae 9 ~ 15 parts, Cortex Dictamni 10 ~ 30 parts, Radix Ophiopogonis 3 ~ 9 parts, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 6 ~ 10 parts, Rhizoma Polygonati 2 ~ 6 parts, Rhizoma Coptidis 6 ~ 10 parts, Fructus Schisandrae Chinensis 5 ~ 10 parts, Radix Rehmanniae 9 ~ 15 parts, Rhizoma Saururi 6 ~ 12 parts, Carex baccans Nees 6 ~ 12 parts, Fructus Amomi 9 ~ 30 parts, Herba Phaenospermatis globosae 2 ~ 6 parts, Sesarmae dehaani 1 ~ 3 part, Herba Aeschynonenes Indicae 2 ~ 4 parts, Ramulus Cinnamomi 15 ~ 35 parts.
The present invention treats the Chinese medicine lotion of erythroderma, it is characterized in that being made up of the crude drug of following weight portion:
Radix Panacis Quinquefolii 9 ~ 15 parts, Rhizoma Polygonati Odorati 4 ~ 9 parts, 6 ~ 8 parts, Natrii Sulfas, 12 ~ 16 parts, Radix Glycyrrhizae, Cornu rhinocerotis 1.5 ~ 2.5 parts, ove Notarchi 1.5 ~ 2.5 parts, Testa sojae atricolor 5 ~ 8 parts, Herba Eriae Graminifoliae 2 ~ 3 parts, Rhizoma Dioscoreae 10 ~ 12 parts, Cortex Dictamni 15 ~ 25 parts, Radix Ophiopogonis 4 ~ 7 parts, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 6 ~ 9 parts, Rhizoma Polygonati 2 ~ 6 parts, Rhizoma Coptidis 6 ~ 8 parts, Fructus Schisandrae Chinensis 6 ~ 9 parts, Radix Rehmanniae 10 ~ 14 parts, Rhizoma Saururi 9 ~ 12 parts, Carex baccans Nees 6 ~ 10 parts, Fructus Amomi 15 ~ 20 parts, Herba Phaenospermatis globosae 3 ~ 5 parts, Sesarmae dehaani 1.5 ~ 2.5 parts, Herba Aeschynonenes Indicae 2.5 ~ 4 parts, Ramulus Cinnamomi 20 ~ 30 parts.
The present invention treats the Chinese medicine lotion of erythroderma, it is characterized in that being made up of the crude drug of following weight portion:
Radix Panacis Quinquefolii 12 parts, Rhizoma Polygonati Odorati 8 parts, 7 parts, Natrii Sulfas, 15 parts, Radix Glycyrrhizae, Cornu rhinocerotis 2 parts, ove Notarchi 2 parts, Testa sojae atricolor 7 parts, Herba Eriae Graminifoliae 2.5 parts, Rhizoma Dioscoreae 11 parts, Cortex Dictamni 20 parts, Radix Ophiopogonis 6 parts, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 9 parts, Rhizoma Polygonati 3 parts, Rhizoma Coptidis 7 parts, Fructus Schisandrae Chinensis 7 parts, Radix Rehmanniae 12 parts, Rhizoma Saururi 12 parts, Carex baccans Nees 8 parts, Fructus Amomi 16 parts, Herba Phaenospermatis globosae 4 parts, Sesarmae dehaani 2.5 parts, Herba Aeschynonenes Indicae 3 parts, Ramulus Cinnamomi 25 parts.
The present invention treats the preparation method of the Chinese medicine lotion of erythroderma, it is characterized in that comprising the following steps:
(1) take each taste Chinese medicine by proportioning, each taste Chinese medicine is soaked 20 ~ 30 minutes in clear water;
(2) medicine soaked is put into twice decoction of marmite part, first time adds 5 times amount soak by water 1.5 ~ 2 hours, filters, and collection filtrate is for subsequent use; Second time adds 4 times of water gagings in marmite, decocts 1 ~ 1.5 hour, filters, and collection filtrate is for subsequent use;
(3) merge twice and decoct gained filtrate, add the 95%(mass fraction of 1.5 times amount) ethanol, limit edged stirs; Leaving standstill makes it precipitate, and gets supernatant for subsequent use;
(4) get supernatant, 80 ~ 90 DEG C of heating concentrate 1.5 ~ 3 hours, and obtain concentrated solution, fill obtains finished product;
(5) when using, 1 times amount rice vinegar is added, external after 200 times of water gaging dilutions, cleaning affected part.
The property of medicine and the pharmacology of the Chinese medicine that the present invention relates to are respectively:
Radix Panacis Quinquefolii: sweet in the mouth, micro-hardship, cool in nature; GUIXIN, lung, kidney channel.There is boosting qi and nourishing yin, the effect of clearing away heat and promoting production of body fluid.Lose for deficiency of vital energy the moon, interior-heat, cough with asthma expectorant blood, deficiency-heat is tired of tired, quenches one's thirst, dryness of the mouth and throat.
Rhizoma Polygonati Odorati: sweet in the mouth, property is put down; Attach to the lung and stomach meridians.Can nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid.Be usually used in cough caused by dryness, chronic cough, the dry throat and mouth of calentura cloudy liquid consumption wound, interior-heat is quenched one's thirst, deficiency of YIN diseases caused by exogenous pathogenic factor, dizzy dizzy, muscle arteries and veins spasm and pain.
Natrii Sulfas: salty in the mouth, hardship, cold in nature; Return stomach, large intestine channel.There is purging heat to relax the bowels, moistening for dryness and softening hard mass, the effect of detumescence of relieving inflammation or internal heat.For excess-heat constipation, constipation due to dry stool, stagnant stomachache, acute appendicitis swells and ache; External treatment acute mastitis, swelling and pain of hemorrhoid.
Radix Glycyrrhizae: sweet in the mouth, property is put down; GUIXIN, lung, spleen, stomach warp.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Cornu rhinocerotis: sour in the mouth, salty, cold in nature; GUIXIN, Liver Channel.Can heat clearing away, removing heat from blood, arresting convulsion, removing toxic substances.Cure mainly the typhoid fever pestilence pathogenic heat attacking blood system in febrile diseases, mania and irritation, irritated, delirium, macule, jaundice, spits blood, epistaxis, hematochezia, swollen ulcer drug.
Ove Notarchi: sweet in the mouth, salty, cold in nature; Return lung, kidney channel.There is clearing away heat and nourishing YIN, the curative effect of softening the hard mass expectorant.Breath with cough for the dryness of the lung, epistaxis, goiter, scrofula.
Testa sojae atricolor: taste is micro-sweet, cool in nature; Return spleen, lung, kidney channel.Can be nourished blood suppressing the hyperactive liver, removing toxic substances of dispeling the wind.Cure mainly headache, deficiency of YIN dysphoria with smothery sensation, night sweat, migratory arthralgia, noxious dampness, carbuncle skin ulcer, dizzy.
Herba Eriae Graminifoliae: sweet in the mouth, cold in nature; Return spleen, stomach warp.Can stomach reinforcing cloudy, born fluid.Cure mainly consumption of body fluid caused by febrile disease, xerostomia excessive thirst, after being ill deficiency-heat, achlorhydria.
Rhizoma Dioscoreae: sweet in the mouth, property is put down; Return spleen, lung, kidney channel.Have spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the effect of the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Cortex Dictamni: bitter in the mouth, cold in nature; Return spleen, stomach, urinary bladder channel.Can heat clearing and damp drying, removing toxic substances of dispeling the wind.Cure mainly damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, beriberoid pyretic arthralgia, jaundice dark coloured urine.
Radix Ophiopogonis: sweet in the mouth, micro-hardship, cold nature; GUIXIN, lung, stomach warp.There is YIN nourishing and the production of body fluid promoting, the effect that lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.
Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae): bitter in the mouth, pungent, cold in nature; Return spleen, liver, stomach warp, poisonous.There is heat-clearing and toxic substances removing, the effect of eliminating stagnation eliminating mass.Cure mainly esophageal carcinoma, carcinoma of gastric cardia, gastric cancer, intestinal cancer, hepatocarcinoma, leukemia, psoriasis, skin ulcer swells.
Rhizoma Polygonati: sweet in the mouth, property is put down; Return spleen, lung, kidney channel.There is boosting qi and nourishing yin, spleen invigorating, lung moistening, effect of kidney tonifying.Cure mainly weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.
Rhizoma Coptidis: bitter in the mouth, cold in nature; GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.There is heat clearing and damp drying, the effect of eliminating fire and detoxication.Cure mainly damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.
Fructus Schisandrae Chinensis: sour in the mouth, sweet, warm in nature; Return lung, the heart, kidney channel.Can restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Be mainly used in chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Radix Rehmanniae: sweet in the mouth, hardship, cold in nature; GUIXIN, liver, kidney channel.Can clearing away heat and cooling blood, promote the production of body fluid and moisturize.Be usually used in acute calenture, unconsciousness due to high fever, macule, excessive thirst is hindered in Tianjin, the haematemesis of bleeding due to blood-heat, epistaxis, and metrorrhagia, has blood in stool, aphtha of the mouth and tongue, laryngopharynx swelling and pain, and consumptive fever is coughed, traumatic pain, carbuncle.
Rhizoma Saururi: taste liver, pungent, cold in nature; Return spleen, large intestine, urinary bladder channel.There is the effect of diuretic dehumidifying, heat-clearing and toxic substances removing.For beriberi, edema, stranguria with turbid discharge, leukorrhagia, carbuncle, erysipelas, furuncle scabies, also dispelling the wind and dampness pathogens pyretic arthralgia.Carex baccans Nees: sweet in the mouth, micro-pungent, property is put down; Return Liver Channel.Can rash cough-relieving, invigorating middle warmer diuretic.Cure mainly measles, chickenpox, pertussis, proctoptosis, edema.
Fructus Amomi: acrid in the mouth, warm in nature cold; Return spleen, stomach, kidney channel.There is removing dampness appetizing, warming spleen and stopping diarrha, antiabortive effect of regulating the flow of vital energy.Cure mainly turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.
Herba Phaenospermatis globosae: sweet in the mouth, micro-puckery, property is put down.Can tonify deficiency spleen invigorating, promoting blood flow to regulate menstruation.For body is empty after being ill, amenorrhea.
Sesarmae dehaani: salty in the mouth, cold in nature; Return spleen channel.Can heat-clearing and toxic substances removing; Removing damp to relieve itching.Cure mainly carbuncle sore tumefacting virus, exudative dermatitis pruritus.
Herba Aeschynonenes Indicae: sweet in the mouth, hardship, cold in nature; Attach to the lung and stomach meridians.Can clearing away heat-damp and promoting diuresis, dispelling pathogenic wind for improving eyesight, lactogenesis.Cure mainly pyretic stranguria, stranguria with blood, edema, have loose bowels, furuncle and phyma, skin ulcer scabies, conjunctival congestion and swelling pain, look unfamiliar nebula, nyctalopia, arthralgia, and puerpera's breast is few.
Ramulus Cinnamomi: acrid in the mouth, sweet, warm in nature; GUIXIN, lung, urinary bladder channel.There is diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the effect of the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Vinegar: sour in the mouth, sweet, warm in nature; Return liver, stomach warp.Can dissipating blood stasis removing food stagnancy, hemostasis, relieving colic caused by ascaris, removing toxic substances.Cure mainly puerperal blood faints, lump in the abdomen, spit blood, epistaxis, has blood in stool, abdominal pain due to worm stagnation, flesh of fish dish poison, carbuncle sore tumefacting virus.Say in amplification on Canon of Materia Medica: " vinegar, distiller grains are main, have rice vinegar, wheat vinegar, Fructus Jujubae vinegar.Rice vinegar is more thick than all vinegar, be used as medicine multiplex it, essence derived from food entirely also, therefore wins poor vinegar ".Rice vinegar is seasoning articles for use common on market, can buy from market.
Beneficial effect of the present invention: Chinese medicine lotion of the present invention can clearing away heat and cooling blood, and detoxification and promoting urination, can rapidly, effectively improve and control the outbreak of erythroderma and spread, cures erythroderma; The all right vigorate qi and replenish the blood of Chinese medicine lotion of the present invention, nourshing Yin and drynsessmoistening prescription simultaneously, strengthens patient's resistance, improve body constitution, and easy to use, and safety, has no side effect, and is applicable to patient's long-term taking.
Detailed description of the invention
Embodiment 1:
Prescription: Radix Panacis Quinquefolii 5g, Rhizoma Polygonati Odorati 2g, Natrii Sulfas 6g, Radix Glycyrrhizae 9g, Cornu rhinocerotis 1.5g, ove Notarchi 1g, Testa sojae atricolor 3g, Herba Eriae Graminifoliae 1g, Rhizoma Dioscoreae 9g, Cortex Dictamni 10g, Radix Ophiopogonis 3g, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 6g, Rhizoma Polygonati 2g, Rhizoma Coptidis 6g, Fructus Schisandrae Chinensis 5g, Radix Rehmanniae 9g, Rhizoma Saururi 6g, Carex baccans Nees 6g, Fructus Amomi 9g, Herba Phaenospermatis globosae 2g, Sesarmae dehaani 1g, Herba Aeschynonenes Indicae 2g, Ramulus Cinnamomi 15g.
Preparation method:
(1) take each taste Chinese medicine by proportioning, each taste Chinese medicine is soaked 23 minutes in clear water;
(2) medicine soaked is put into twice decoction of marmite part, first time adds 5 times amount soak by water 1.5 hours, filters, and collection filtrate is for subsequent use; Second time adds 4 times of water gagings in marmite, decocts 1 hour, filters, and collection filtrate is for subsequent use;
(3) merge twice and decoct gained filtrate, add the 95%(mass fraction of 1.5 times amount) ethanol, limit edged stirs; Leaving standstill makes it precipitate, and gets supernatant for subsequent use;
(4) get supernatant, 80 ~ 90 DEG C of heating concentrate 3 hours, and obtain concentrated solution, fill obtains finished product, every bottle of 10g.
Using method: add 1 times amount rice vinegar, external after 200 times of water gaging dilutions, cleaning entire patient, particularly affected part, each one bottle, once a day.
Embodiment 2:
Prescription: Radix Panacis Quinquefolii 9g, Rhizoma Polygonati Odorati 4g, Natrii Sulfas 6g, Radix Glycyrrhizae 12g, Cornu rhinocerotis 1.5g, ove Notarchi 1.5g, Testa sojae atricolor 5g, Herba Eriae Graminifoliae 2g, Rhizoma Dioscoreae 10g, Cortex Dictamni 15g, Radix Ophiopogonis 4g, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 6g, Rhizoma Polygonati 3g, Rhizoma Coptidis 6g, Fructus Schisandrae Chinensis 6g, Radix Rehmanniae 10g, Rhizoma Saururi 9g, Carex baccans Nees 7g, Fructus Amomi 15g, Herba Phaenospermatis globosae 3g, Sesarmae dehaani 1.5g, Herba Aeschynonenes Indicae 2.5g, Ramulus Cinnamomi 20g.
Preparation method and using method identical with embodiment 1.
Embodiment 3:
Prescription: Radix Panacis Quinquefolii 12g, Rhizoma Polygonati Odorati 8g, Natrii Sulfas 7g, Radix Glycyrrhizae 15g, Cornu rhinocerotis 2g, ove Notarchi 2g, Testa sojae atricolor 7g, Herba Eriae Graminifoliae 2.5g, Rhizoma Dioscoreae 11g, Cortex Dictamni 20g, Radix Ophiopogonis 6g, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 9g, Rhizoma Polygonati 3g, Rhizoma Coptidis 7g, Fructus Schisandrae Chinensis 7g, Radix Rehmanniae 12g, Rhizoma Saururi 12g, Carex baccans Nees 8g, Fructus Amomi 16g, Herba Phaenospermatis globosae 4g, Sesarmae dehaani 2.5g, Herba Aeschynonenes Indicae 3g, Ramulus Cinnamomi 25g.
Preparation method:
(1) take each taste Chinese medicine by proportioning, each taste Chinese medicine is soaked 30 minutes in clear water;
(2) medicine soaked is put into twice decoction of marmite part, first time adds 5 times amount soak by water 2 hours, filters, and collection filtrate is for subsequent use; Second time adds 4 times of water gagings in marmite, decocts 1.5 hours, filters, and collection filtrate is for subsequent use;
(3) merge twice and decoct gained filtrate, add the 95%(mass fraction of 1.5 times amount) ethanol, limit edged stirs; Leaving standstill makes it precipitate, and gets supernatant for subsequent use;
(4) get supernatant, 80 ~ 90 DEG C of heating concentrate 2 hours, and obtain concentrated solution, fill obtains finished product, every bottle of 10g.
Using method is identical with embodiment 1.
Embodiment 4:
Radix Panacis Quinquefolii 15g, Rhizoma Polygonati Odorati 9g, Natrii Sulfas 8g, Radix Glycyrrhizae 16g, Cornu rhinocerotis 2.5g, ove Notarchi 2.5g, Testa sojae atricolor 8g, Herba Eriae Graminifoliae 3g, Rhizoma Dioscoreae 12g, Cortex Dictamni 25g, Radix Ophiopogonis 7g, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 9g, Rhizoma Polygonati 4g, Rhizoma Coptidis 8g, Fructus Schisandrae Chinensis 9g, Radix Rehmanniae 14g, Rhizoma Saururi 12g, Carex baccans Nees 9g, Fructus Amomi 20g, Herba Phaenospermatis globosae 5g, Sesarmae dehaani 2.5g, Herba Aeschynonenes Indicae 4g, Ramulus Cinnamomi 30g.
Preparation method and using method identical with embodiment 3.
Embodiment 5:
Radix Panacis Quinquefolii 15 parts, Rhizoma Polygonati Odorati 10 parts, 9 parts, Natrii Sulfas, 20 parts, Radix Glycyrrhizae, Cornu rhinocerotis 3 parts, ove Notarchi 3 parts, Testa sojae atricolor 9 parts, Herba Eriae Graminifoliae 3 parts, Rhizoma Dioscoreae 15 parts, Cortex Dictamni 30 parts, Radix Ophiopogonis 9 parts, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 10 parts, Rhizoma Polygonati 5 parts, Rhizoma Coptidis 10 parts, Fructus Schisandrae Chinensis 10 parts, Radix Rehmanniae 15 parts, Rhizoma Saururi 12 parts, Carex baccans Nees 10 parts, Fructus Amomi 30 parts, Herba Phaenospermatis globosae 6 parts, Sesarmae dehaani 3 parts, Herba Aeschynonenes Indicae 4 parts, Ramulus Cinnamomi 35g.
Preparation method and using method identical with embodiment 3.
Embodiment 6: clinical observation
One, clinical data
In January, 2012 to 2013, year December, was total to random selecting erythroderma patient 280 example.Wherein, male patient 140 example, female patient 140 example.
Two, efficacy assessment standard
Cure: the symptoms such as the diffuse flushing of whole skin, infiltration, swelling, desquamation disappear completely, do not recur, recover orthobiosis completely more.
Effective: the symptoms such as the diffuse flushing of whole skin, infiltration, swelling, desquamation obviously disappear, and skin involvement area no longer expands and spreads, and the state of an illness is controlled, and substantially recovers orthobiosis.
Effective: the symptoms such as the diffuse flushing of whole skin, infiltration, swelling, desquamation are controlled, skin improves, and skin involvement area spreading rate declines.
Invalid: the contrast for the treatment of before and after look, function, symptom, sign take a turn for the better not obvious.
Three, therapeutic outcome
280 routine patient's cure rates are 79.3%, and effective percentage is 17.1%, and obvious effective rate 3.6%, total effective rate reaches 100%.
Four, typical clinical case
Case 1, Lee, man, 18 months.Their early stage, there is erythema in patient's skin around the rectum, then merge in flakes very soon, prolong and buttocks and two thigh places, and be rapidly to whole body development, gradually there is branny desquamation in skin surface, and constantly come off, formed again after coming off, and bits skin is gradually large lamellar, and with diarrhoea, be diagnosed as erythroderma desquamativum.The continuous use embodiment of the present invention 4 gained Chinese medicine lotion is after 20 days, and symptom of diarrhea disappears, and afflicted skin is no longer peeled, and scurf obviously disappears, and after 27 days, squama disappears completely; After adhere to using the embodiment of the present invention 2 gained Chinese medicine lotion after 12 days, skin recovers normal condition, and erythroderma is followed up a case by regular visits to and do not recurred.
Case 2, Liu, female, 13 years old.Patient skin flushing, incrustation, accompany serious pruritus, a large amount of desquamation, Head And Face squama is thick greasy simultaneously, the sheet decortication of palm sole of the foot portion, and with the high heat of whole body, is diagnosed as erythroderma.The continuous use embodiment of the present invention 3 gained Chinese medicine lotion after 22 days whole body squama disappear, after adhere to using the embodiment of the present invention 1 gained Chinese medicine lotion after 15 days, skin recovers smooth, and erythroderma is followed up a case by regular visits to and do not recurred.
Case 3, Tan, man, 15 years old.Differing in size appears in patient facial region and extremity, erose erythema, with branny desquamation on speckle, and with serious pruritus, is diagnosed as erythroderma.The continuous use embodiment of the present invention 2 gained Chinese medicine lotion after 18 days squama obviously disappear, after 27 days, squama disappears substantially, after adhere to using the embodiment of the present invention 1 gained Chinese medicine lotion after 15 days, erythema disappears, and erythroderma is followed up a case by regular visits to and do not recurred.
Case 4, Xu certain, man, 28 years old.There is large stretch of irregular erythema in patient's extremity and trunk, erythema adheres to squama, and constantly comes off, formed again after coming off, with skin turgor, be diagnosed as erythroderma.The continuous use embodiment of the present invention 5 gained Chinese medicine lotion is after 14 days, and skin turgor disappears, and skin involvement area is expanded no longer rapidly, after 26 days, squama obviously disappears, after adhere to using the embodiment of the present invention 2 gained Chinese medicine lotion after 21 days, erythema disappears, and erythroderma is followed up a case by regular visits to and do not recurred.

Claims (4)

1. treat a Chinese medicine lotion for erythroderma, it is characterized in that being made up of the herbal raw material of following weight portion:
Radix Panacis Quinquefolii 5 ~ 15 parts, Rhizoma Polygonati Odorati 2 ~ 10 parts, 6 ~ 9 parts, Natrii Sulfas, 9 ~ 20 parts, Radix Glycyrrhizae, Cornu rhinocerotis 1.5 ~ 3 parts, ove Notarchi 1 ~ 3 part, Testa sojae atricolor 3 ~ 9 parts, Herba Eriae Graminifoliae 1 ~ 3 part, Rhizoma Dioscoreae 9 ~ 15 parts, Cortex Dictamni 10 ~ 30 parts, Radix Ophiopogonis 3 ~ 9 parts, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 6 ~ 10 parts, Rhizoma Polygonati 2 ~ 6 parts, Rhizoma Coptidis 6 ~ 10 parts, Fructus Schisandrae Chinensis 5 ~ 10 parts, Radix Rehmanniae 9 ~ 15 parts, Rhizoma Saururi 6 ~ 12 parts, Carex baccans Nees 6 ~ 12 parts, Fructus Amomi 9 ~ 30 parts, Herba Phaenospermatis globosae 2 ~ 6 parts, Sesarmae dehaani 1 ~ 3 part, Herba Aeschynonenes Indicae 2 ~ 4 parts, Ramulus Cinnamomi 15 ~ 35 parts.
2. the Chinese medicine lotion for the treatment of erythroderma according to claim 1, is characterized in that being made up of the crude drug of following weight portion:
Radix Panacis Quinquefolii 9 ~ 15 parts, Rhizoma Polygonati Odorati 4 ~ 9 parts, 6 ~ 8 parts, Natrii Sulfas, 12 ~ 16 parts, Radix Glycyrrhizae, Cornu rhinocerotis 1.5 ~ 2.5 parts, ove Notarchi 1.5 ~ 2.5 parts, Testa sojae atricolor 5 ~ 8 parts, Herba Eriae Graminifoliae 2 ~ 3 parts, Rhizoma Dioscoreae 10 ~ 12 parts, Cortex Dictamni 15 ~ 25 parts, Radix Ophiopogonis 4 ~ 7 parts, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 6 ~ 9 parts, Rhizoma Polygonati 2 ~ 6 parts, Rhizoma Coptidis 6 ~ 8 parts, Fructus Schisandrae Chinensis 6 ~ 9 parts, Radix Rehmanniae 10 ~ 14 parts, Rhizoma Saururi 9 ~ 12 parts, Carex baccans Nees 6 ~ 10 parts, Fructus Amomi 15 ~ 20 parts, Herba Phaenospermatis globosae 3 ~ 5 parts, Sesarmae dehaani 1.5 ~ 2.5 parts, Herba Aeschynonenes Indicae 2.5 ~ 4 parts, Ramulus Cinnamomi 20 ~ 30 parts.
3. the Chinese medicine lotion for the treatment of erythroderma according to claim 1, is characterized in that being made up of the crude drug of following weight portion:
Radix Panacis Quinquefolii 12 parts, Rhizoma Polygonati Odorati 8 parts, 7 parts, Natrii Sulfas, 15 parts, Radix Glycyrrhizae, Cornu rhinocerotis 2 parts, ove Notarchi 2 parts, Testa sojae atricolor 7 parts, Herba Eriae Graminifoliae 2.5 parts, Rhizoma Dioscoreae 11 parts, Cortex Dictamni 20 parts, Radix Ophiopogonis 6 parts, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 9 parts, Rhizoma Polygonati 3 parts, Rhizoma Coptidis 7 parts, Fructus Schisandrae Chinensis 7 parts, Radix Rehmanniae 12 parts, Rhizoma Saururi 12 parts, Carex baccans Nees 8 parts, Fructus Amomi 16 parts, Herba Phaenospermatis globosae 4 parts, Sesarmae dehaani 2.5 parts, Herba Aeschynonenes Indicae 3 parts, Ramulus Cinnamomi 25 parts.
4. the preparation method of the Chinese medicine lotion for the treatment of erythroderma according to claim 1, is characterized in that comprising the following steps:
(1) take each taste Chinese medicine by proportioning, each taste Chinese medicine is soaked 20 ~ 30 minutes in clear water;
(2) medicine soaked is put into twice decoction of marmite part, first time adds 5 times amount soak by water 1.5 ~ 2 hours, filters, and collection filtrate is for subsequent use; Second time adds 4 times of water gagings in marmite, decocts 1 ~ 1.5 hour, filters, and collection filtrate is for subsequent use;
(3) merge twice and decoct gained filtrate, add the 95%(mass fraction of 1.5 times amount) ethanol, limit edged stirs; Leaving standstill makes it precipitate, and gets supernatant for subsequent use;
(4) get supernatant, 80 ~ 90 DEG C of heating concentrate 1.5 ~ 3 hours, and obtain concentrated solution, fill obtains finished product;
(5) when using, 1 times amount rice vinegar is added, external after 200 times of water gaging dilutions, cleaning affected part.
CN201410620697.2A 2014-11-07 2014-11-07 Traditional Chinese medicine lotion for treating erythroderma and preparation method thereof Pending CN104367925A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101653562A (en) * 2009-09-15 2010-02-24 周大红 Traditional Chinese medicine for treating erythrodermic psoriasis
CN101810797A (en) * 2010-05-12 2010-08-25 韦品琦 Chinese medicinal preparation for curing psoriasis and preparation method thereof
CN102470163A (en) * 2009-07-23 2012-05-23 Igisu株式会社 Composition for external preparation for skin
CN103656542A (en) * 2012-09-05 2014-03-26 杨波 Drug for treating erythroderma desquamativum and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN102470163A (en) * 2009-07-23 2012-05-23 Igisu株式会社 Composition for external preparation for skin
CN101653562A (en) * 2009-09-15 2010-02-24 周大红 Traditional Chinese medicine for treating erythrodermic psoriasis
CN101810797A (en) * 2010-05-12 2010-08-25 韦品琦 Chinese medicinal preparation for curing psoriasis and preparation method thereof
CN103656542A (en) * 2012-09-05 2014-03-26 杨波 Drug for treating erythroderma desquamativum and preparation method thereof

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