CN103656542A - Drug for treating erythroderma desquamativum and preparation method thereof - Google Patents
Drug for treating erythroderma desquamativum and preparation method thereof Download PDFInfo
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- CN103656542A CN103656542A CN201210323561.6A CN201210323561A CN103656542A CN 103656542 A CN103656542 A CN 103656542A CN 201210323561 A CN201210323561 A CN 201210323561A CN 103656542 A CN103656542 A CN 103656542A
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Abstract
The invention discloses a drug for treating erythroderma desquamativum and a preparation method thereof. The drug aims to solve the problem in the prior art that the erythroderma desquamativum is treated by hormone to bring large side effects to patients while the erythroderma desquamativum treating is performed. The drug is prepared from the following raw materials in parts by weight: 5-10 parts of coptis, 6-8 parts of henry hemsleya root, 3-5 parts of hemsleya macrosperma, 3-5 parts of blackberry lily, 5-10 parts of ginger, 3-5 parts of onion and 20-200 parts of cactus. The drug disclosed by the invention can improve immunity of human body so as to treat the erythroderma desquamativum by autoimmunity of the human body. The drug adopts traditional Chinese medicine components, thereby being free of toxic side effect, good in curative effect and capable of effectively shortening the treatment cycle, reducing the treatment cost and reducing the economic burden of patients.
Description
Technical field
The present invention relates to field of medicaments, especially a kind of medicine for the treatment of erythroderma desquamativum and preparation method thereof.
Background technology
Erythroderma is a kind of serious systemic disease, and its principal character is that extensive and obvious erythema infiltrates infringement with pityrosporum shape desquamation, and skin involvement area is greater than more than 90% conventionally.According to data, adult's erythroderma accounts for 0.3% of department of dermatologry patient sum, take male as main, is mainly in 45 years old above person.According to the difference of the factor of curing the disease, cocoa is summarized as 4 classes: (1) is secondary to the erythroderma that other dermatosiss cause; ; (2) erythroderma that external or systemic administration cause; (3) erythroderma causing due to malignant tumor; (4) other factors, such as after hepatitis, radiotherapy, after shell operation companion blood transfusion etc., the erythroderma causing.Wherein, erythroderma desquamativum is a kind of comparatively common erythroderma.
At present, treatment erythroderma desquamativum mainly adopts hormone to treat.It,, in treatment erythroderma, brings great side effect to patient, causes weight in patients increase etc., has a strong impact on the orthobiosis after patient cures.
Summary of the invention
Goal of the invention of the present invention is: for prior art, adopt hormone therapy erythroderma desquamativum, in treatment erythroderma, to patient, bring the problem of great side effect, a kind of medicine for the treatment of erythroderma desquamativum is provided, it prevents that by medicine erythroderma from infecting, can improve body immunity, by human body autoimmune, reach the object for the treatment of erythroderma desquamativum simultaneously.This medicine adopts Chinese medicine ingredients, has no side effect, and therapeutic effect is good, can effectively shorten treatment cycle, reduces treatment cost, alleviates patient's economy and body burden.
The technical solution used in the present invention is as follows:
Treat a medicine for erythroderma desquamativum, adopt and comprise that the raw material of following weight portion is prepared from: 5-10 part Rhizoma Coptidis, 6-8 part Neoalsomitra integrifoliola (Cogn.) Hucth., 3-5 part Radix Hemsleyae Macrospermae, 3-5 part Rhizoma Belamcandae, 5-10 part Rhizoma Zingiberis Recens, 3-5 part Herba Alii fistulosi, 20-200 part Radix et Caulis Opuntiae Dillenii.
The raw material that also comprises following weight portion: 5-10 part Radix Angelicae Sinensis, 3-5 part Rhizoma Polygonati Odorati, 3-5 part Rhizoma Chuanxiong, 6-10 part Fructus Jujubae, 6-10 part Radix Glycyrrhizae.
The preparation method that is used for the medicine of above-mentioned treatment erythroderma desquamativum, comprises the steps:
(1) by proportioning, take each component, standby;
(2) Rhizoma Coptidis, Neoalsomitra integrifoliola (Cogn.) Hucth., Radix Hemsleyae Macrospermae, Rhizoma Belamcandae, Herba Alii fistulosi are decocted with water respectively 3 times, obtain filtrate;
(3) by Radix et Caulis Opuntiae Dillenii peeling, pulverize;
(4) remaining ingredient is ground into powder, then fine powder, filtrate is mixed with Radix et Caulis Opuntiae Dillenii.
In described step (2), Rhizoma Coptidis, Neoalsomitra integrifoliola (Cogn.) Hucth., Radix Hemsleyae Macrospermae, Rhizoma Belamcandae, Herba Alii fistulosi are decocted with water respectively 3 times, decoct with water for the first time 1-3h, decoct with water for the second time 2-4h, decoct with water for the third time 1-2h, merging filtrate.
In described step (3), by Radix et Caulis Opuntiae Dillenii peeling, pulverize in flakes or piece.
The present invention is directed to the feature of erythroderma desquamativum, it is main adopting antiinflammatory, sterilization, and health is adjusted to auxiliary mode, according to the principle of tonic, and reasonably combined each component.Wherein, Rhizoma Coptidis, Neoalsomitra integrifoliola (Cogn.) Hucth., Radix Hemsleyae Macrospermae, Rhizoma Belamcandae four tastes have strong heat-clearing and toxic substances removing, and the effect of anti-inflammation and sterilization can effectively prevent that patient from further infecting.For the feature of above-mentioned four Chinese medicine, the present invention adopts the mode that decocts 3 times, and it can make the effective ingredient in medicine effectively discharge, and improves therapeutic effect.Meanwhile, in the present invention, be also aided with Rhizoma Zingiberis Recens, Herba Alii fistulosi and Radix et Caulis Opuntiae Dillenii.Rhizoma Zingiberis Recens is warm in nature, pungent, has the effect of heating cold expelling, warming middle-JIAO stomach invigorating, preventing or arresting vomiting parasite killing, is among the peoplely usually used in treating the diseases such as flu, vomiting, dysentery.Rhizoma Zingiberis Recens can play the object of warming middle-JIAO stomach invigorating, can promote patient's appetite, adjusts intestinal digestion balance in patient body.Herba Alii fistulosi nature and flavor, Xin Wen, has a surname's of activating yang numbness, relieving the exterior syndrome by diaphoresis, stomach invigorating is eliminated the phlegm, orectic function.Meanwhile, Herba Alii fistulosi can also relieving the exterior syndrome by diaphoresis, can control anemofrigid cold, rheumatism general pain, paralysis card.In Herba Alii fistulosi, contain protein, fat, sugar, carotene, carbohydrate, inorganic salt, vitamin etc., its medicinal ingredient is Herba Alii fistulosi Bulbus Allii bacteriocidin, volatilization wet goods, has the effect of bactericidal antiphlogistic.And that Radix et Caulis Opuntiae Dillenii itself has is edible, the beauty treatment of medicine and health care, in the present invention, adopt Radix et Caulis Opuntiae Dillenii, Main Basis medicine food is with the principle of mending.Radix et Caulis Opuntiae Dillenii itself has the effect of antiinflammatory, sterilization, and meanwhile, it can provide essential nutritional labeling for patient.Radix et Caulis Opuntiae Dillenii itself has light sweet taste, cool taste, is suitable for eating, therefore, the present invention directly pulverizes Radix et Caulis Opuntiae Dillenii, directly mixes with other components, directly edible, can make patient in the component that effectively absorbs the drug, the mouthfeel having kept, is convenient to taking of patient.
As preferably, the present invention also comprises five of Radix Angelicae Sinensis, Rhizoma Polygonati Odorati, Rhizoma Chuanxiong, Fructus Jujubae, Radix Glycyrrhizae.Radix Angelicae Sinensis, Rhizoma Polygonati Odorati, Rhizoma Chuanxiong, Fructus Jujubae four tastes have nourishing healthy energy, and the effect of invigorating qi and benefiting blood, can promote patient's self recovery, for patient provides necessary nutrition.And the king that Radix Glycyrrhizae is BAICAO has the effect of mediation hundred medicines.
As preferably, preparation method of the present invention is significantly different from the preparation method of other drug.The present invention, according to the feature of different component, decocts, is ground into fine powder, pulverizes in bulk or honor different component respectively.Prepared medicine can directly eat, and has good mouthfeel simultaneously, is convenient to the edible of patient.
The specific embodiment
Disclosed all features in this description, or the step in disclosed all methods or process, except mutually exclusive feature and/or step, all can combine by any way.
Disclosed arbitrary feature in this description, unless narration especially all can be replaced by other equivalences or the alternative features with similar object.That is,, unless narration especially, each feature is an example in a series of equivalences or similar characteristics.
Embodiment 1
Treat a medicine for erythroderma desquamativum, adopt and comprise that the raw material of following weight portion is prepared from: 10g Rhizoma Coptidis, 8g Neoalsomitra integrifoliola (Cogn.) Hucth., 5g Radix Hemsleyae Macrospermae, 5g Rhizoma Belamcandae, 6g Rhizoma Zingiberis Recens, 3g Herba Alii fistulosi, 20g Radix et Caulis Opuntiae Dillenii, the quality sum of above seven medicines is former medicine quality.
Each component is decocted with water 2 times, and the decocting that adds for the first time 5 times of former medicine quality boils 1h, and the decocting that adds for the second time 15 times of former medicine quality boils 2h, collects merging filtrate, is condensed into 20-40ml.In concentrated solution, add adjuvant, make 50 pills, the quality of every pill is 2g.
Embodiment 2
Take respectively 6g Rhizoma Coptidis, 6g Neoalsomitra integrifoliola (Cogn.) Hucth., 4g Radix Hemsleyae Macrospermae, 3g Rhizoma Belamcandae, 7g Rhizoma Zingiberis Recens, 5g Herba Alii fistulosi, 50g Radix et Caulis Opuntiae Dillenii, the quality sum of above seven medicines is former medicine quality.Respectively above-mentioned each component is mixed, decoct with water 3 times.The decocting that adds for the first time 3 times of former medicine quality boils 0.5h, and the decocting that adds for the second time 5 times of former medicine quality boils 1h, and the decocting that adds for the third time 8 times of former medicine quality boils 2h, collects filtrate.In filtrate, add water to 200mL, be divided into 10 parts, every part of 20mL, makes the oral liquid of every of 20mL.
Embodiment 3
Take respectively 8g Rhizoma Coptidis, 8g Neoalsomitra integrifoliola (Cogn.) Hucth., 3g Radix Hemsleyae Macrospermae, 4g Rhizoma Belamcandae, 10g Rhizoma Zingiberis Recens, 5g Herba Alii fistulosi, 200g Radix et Caulis Opuntiae Dillenii, standby.
Rhizoma Coptidis, Neoalsomitra integrifoliola (Cogn.) Hucth., Radix Hemsleyae Macrospermae, Rhizoma Belamcandae, Herba Alii fistulosi are decocted with water respectively 3 times, the decocting that adds for the first time 5 times of aforementioned five medicine quality summations boils 1h, the decocting that adds for the second time 8 times of aforementioned five medicine quality summations boils 2h, the decocting that adds for the third time 4 times of aforementioned five medicine quality summations boils 1.5h, collects filtrate.
Rhizoma Zingiberis Recens powder is broken into fine powder, by after Radix et Caulis Opuntiae Dillenii peeling, makes Radix et Caulis Opuntiae Dillenii honor.In Radix et Caulis Opuntiae Dillenii honor, add fine powder, filtrate, mix homogeneously, obtains medicine of the present invention.
Embodiment 4
Take respectively 6g Rhizoma Coptidis, 6g Neoalsomitra integrifoliola (Cogn.) Hucth., 3g Radix Hemsleyae Macrospermae, 5g Rhizoma Belamcandae, 6g Rhizoma Zingiberis Recens, 3g Herba Alii fistulosi, 150g Radix et Caulis Opuntiae Dillenii, 10g Radix Angelicae Sinensis, 3g Rhizoma Polygonati Odorati, 3g Rhizoma Chuanxiong, 9g Fructus Jujubae, 8g Radix Glycyrrhizae, standby.
Rhizoma Coptidis, Neoalsomitra integrifoliola (Cogn.) Hucth., Radix Hemsleyae Macrospermae, Rhizoma Belamcandae, Herba Alii fistulosi are decocted with water respectively 3 times, the decocting that adds for the first time 20 times of aforementioned five medicine quality summations boils 3h, the decocting that adds for the second time 25 times of aforementioned five medicine quality summations boils 4h, the decocting that adds for the third time 5 times of aforementioned five medicine quality summations boils 1h, collects filtrate.
Rhizoma Zingiberis Recens, Radix Angelicae Sinensis, Rhizoma Polygonati Odorati, Rhizoma Chuanxiong, Fructus Jujubae, Radix Glycyrrhizae powder are broken into fine powder, by after Radix et Caulis Opuntiae Dillenii peeling, make Radix et Caulis Opuntiae Dillenii honor.In Radix et Caulis Opuntiae Dillenii honor, add fine powder, filtrate, mix homogeneously, obtains medicine of the present invention.
Embodiment 5
Take respectively 9g Rhizoma Coptidis, 6g Neoalsomitra integrifoliola (Cogn.) Hucth., 3g Radix Hemsleyae Macrospermae, 3g Rhizoma Belamcandae, 10g Rhizoma Zingiberis Recens, 5g Herba Alii fistulosi, 80g Radix et Caulis Opuntiae Dillenii, 6g Radix Angelicae Sinensis, 5g Rhizoma Polygonati Odorati, 4g Rhizoma Chuanxiong, 6g Fructus Jujubae, 10g Radix Glycyrrhizae, standby.
Rhizoma Coptidis, Neoalsomitra integrifoliola (Cogn.) Hucth., Radix Hemsleyae Macrospermae, Rhizoma Belamcandae, Herba Alii fistulosi are decocted with water respectively 3 times, the decocting that adds for the first time 5 times of aforementioned five medicine quality summations boils 1h, the decocting that adds for the second time 10 times of aforementioned five medicine quality summations boils 2h, and the decocting that adds for the third time 5 times of aforementioned five medicine quality summations boils 1h, collects filtrate.
Rhizoma Zingiberis Recens, Radix Angelicae Sinensis, Rhizoma Polygonati Odorati, Rhizoma Chuanxiong, Fructus Jujubae, Radix Glycyrrhizae powder are broken into fine powder, by after Radix et Caulis Opuntiae Dillenii peeling, make Radix et Caulis Opuntiae Dillenii honor.In Radix et Caulis Opuntiae Dillenii honor, add fine powder, filtrate, mix homogeneously, obtains medicine of the present invention.
Experiment effect
Choose 20 routine erythroderma desquamativumes and treat, wherein 14 female, 6 men, average year 52.3 years old.Wherein, 12 patients take recovery from illness in medicine 5-7 of the present invention days, and 5 patients fully recover in adopting medicine 8-15 of the present invention days, and 2 patients adopt interior recovery from illness in medicine 16-25 of the present invention days, after 1 patient adopts 1 first quarter moon of Drug therapy of the present invention, fully recover.In using process of the present invention, patient body is in good condition, does not occur the reaction of any side effect.Above experimental result explanation, medicine of the present invention has no side effect, and treatment cycle is short, and erythroderma desquamativum is had to good therapeutic effect.
The present invention is not limited to the aforesaid specific embodiment.The present invention expands to any new feature or any new combination disclosing in this manual, and the arbitrary new method disclosing or step or any new combination of process.
Claims (5)
1. treat a medicine for erythroderma desquamativum, adopt and comprise that the raw material of following weight portion is prepared from: 5-10 part Rhizoma Coptidis, 6-8 part Neoalsomitra integrifoliola (Cogn.) Hucth., 3-5 part Radix Hemsleyae Macrospermae, 3-5 part Rhizoma Belamcandae, 5-10 part Rhizoma Zingiberis Recens, 3-5 part Herba Alii fistulosi, 20-200 part Radix et Caulis Opuntiae Dillenii.
2. treat according to claim 1 the medicine of erythroderma desquamativum, it is characterized in that, also comprise the raw material of following weight portion: 5-10 part Radix Angelicae Sinensis, 3-5 part Rhizoma Polygonati Odorati, 3-5 part Rhizoma Chuanxiong, 6-10 part Fructus Jujubae, 6-10 part Radix Glycyrrhizae.
3. according to the preparation method for the treatment of the medicine of erythroderma desquamativum described in claim 1 or 2, it is characterized in that, comprise the steps:
(1) by proportioning, take each component, standby;
(2) Rhizoma Coptidis, Neoalsomitra integrifoliola (Cogn.) Hucth., Radix Hemsleyae Macrospermae, Rhizoma Belamcandae, Herba Alii fistulosi are decocted with water respectively 3 times, obtain filtrate;
(3) by Radix et Caulis Opuntiae Dillenii peeling, pulverize;
(4) remaining ingredient is ground into powder, then fine powder, filtrate is mixed with Radix et Caulis Opuntiae Dillenii.
4. treat according to claim 3 the preparation method of the medicine of erythroderma desquamativum, it is characterized in that, in described step (2), Rhizoma Coptidis, Neoalsomitra integrifoliola (Cogn.) Hucth., Radix Hemsleyae Macrospermae, Rhizoma Belamcandae, Herba Alii fistulosi are decocted with water respectively 3 times, decoct with water for the first time 1-3h, decoct with water for the second time 2-4h, decoct with water for the third time 1-2h, merging filtrate.
5. treat according to claim 3 the preparation method of the medicine of erythroderma desquamativum, it is characterized in that, in described step (3), by Radix et Caulis Opuntiae Dillenii peeling, pulverize in flakes or piece.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104367925A (en) * | 2014-11-07 | 2015-02-25 | 济南高达信息技术有限公司 | Traditional Chinese medicine lotion for treating erythroderma and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104367925A (en) * | 2014-11-07 | 2015-02-25 | 济南高达信息技术有限公司 | Traditional Chinese medicine lotion for treating erythroderma and preparation method thereof |
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Application publication date: 20140326 |