CN104367702A - Traditional Chinese medicinal composition for treating tumors - Google Patents

Traditional Chinese medicinal composition for treating tumors Download PDF

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CN104367702A
CN104367702A CN201410683226.6A CN201410683226A CN104367702A CN 104367702 A CN104367702 A CN 104367702A CN 201410683226 A CN201410683226 A CN 201410683226A CN 104367702 A CN104367702 A CN 104367702A
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herba
traditional chinese
chinese medicine
medicinal composition
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任立杰
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • A61K36/04Rhodophycota or rhodophyta (red algae), e.g. Porphyra
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/41Crassulaceae (Stonecrop family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/44Ebenaceae (Ebony family), e.g. persimmon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed

Abstract

The invention relates to a traditional Chinese medicinal composition for treating tumors. The traditional Chinese medicinal composition is composed of trametes versicolor, patience dock root, selaginella moellendorfii hieron, peanut coat, persimmon leaves, sixangular dysosma rhizome, anchusa azurea, Chinese elder herb, emblic leafflower fruit, fewflower lysionotus herb, chondrus crispus, pumex, asparagopsis, dindygulen peperomia herb, myosoton aquaticum, physalis angulata, herba orostachyos, princes-feather fruit, ulva lactuca, linden viburnum and armillaria tabescens. By virtue of the synergistic effect of all the traditional Chinese medicine raw materials, the traditional Chinese medicinal composition disclosed by the invention has functions of promoting blood circulation, removing stasis, clearing damp, reducing phlegm, softening hardness, dissipating stagnation, and clearing away heat and toxic materials; moreover, patience dock root, selaginella moellendorfii hieron, peanut coat and persimmon leaves have good effect on leukopenia and thrombocytopenia after radiochemotherapy on tumors, and body immunity is enhanced when tumor cells are killed; the traditional Chinese medicinal composition has the advantages of relieving pain and taking good curative effect on tumors caused by various reasons; and the traditional Chinese medicinal composition is high in efficiency and free from toxic and side effects.

Description

The Chinese medicine composition for the treatment of tumor
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of tumor.
Background technology
Tumor be body under various carcinogenic factor effect, some cells of local organization lose the normal regulation to its growth on gene level, cause its clonal abnormality hypertrophy and the neoplasm that formed.It is generally acknowledged, tumor cell is monoclonicity, and all oncocytes namely in a tumor are all offsprings of the cell of a sudden change.
Tumor tissues is made up of cancerous cell and interstitial, and cancerous cell is the abnormal proliferation cell come by normal cell turnover.Tumor can occur in many Organ and tissues of human body.According to tumor, benign tumor and malignant tumor two class are divided into the size of harm and growth characteristics thereof.Benign tumor poor growth, in expansive growth, often there is complete peplos on surface, less General Symptoms except local symptom, tissue infiltration, not to whole body transfer, does not easily recur after excision yet towards periphery, less to body harm, as lipoma, hemangioma, adenoma, cyst etc.Malignant growth is rapid, growth tissue infiltration towards periphery often, surface youngster, without peplos, often has whole body to shift, the visible atypical karyokinesis of pathologic finding, except local symptom, General Symptoms is obvious, and end-stage patients have more existing cachexia, and after excision, relapse rate is high, large to body harm, as osteocarcinoma, the esophageal carcinoma, hepatocarcinoma, pulmonary carcinoma, leukemia, osteosarcoma etc.The sick rate of the Deschampsia caespitosa katydid of malignant tumor has the trend raised year by year, in the cause of death of various disease, also account for former position, because of but a kind of disease of keypoint control.
At present, operation, radiotherapy, chemotherapy remain the essential therapeutic arsenals of tumor, and after excision, relapse rate is high, and Radiotherapy chemotherapy side effect is large, and making patients is painful.Herbal treatment not only has inhibitory action to tumor cell, can also strengthen immunologic function by auxiliary body, greatly alleviate symptom and the misery of cancer patient, improve life quality, extending life.
Summary of the invention
The Chinese medicine composition of the treatment tumor that the object of the present invention is to provide a kind of effective percentage high.
The technical solution adopted for the present invention to solve the technical problems is: the Chinese medicine composition for the treatment of tumor, is made up of the raw material of Chinese medicine of following weight proportioning: Coriolous Dersicolor (Fr.) Quel 5-9g, Radix Rumicis Patientiae 3-5g, Herba Selaginellae Involventis 3-8g, Testa arachidis hypogaeae 5-15g, Folium Kaki 5-10g, Radix et Rhizoma Dysosmatis 3-8g, Folium Fumicis Dentati 3-5g, Herba Sambuci Chiensis 5-7g, Fructus Phyllanthi 3-5g, Herba Lysionoti Pauciflori 3-6g, chondrus ocellatus Holmes 3-8g, Pumex 3-5g, Asparagus toxiformis (Delile) Coll et Harv 3-8g, Herba Peperomiae Dindygulensis 3-5g, Herba malachii aquatici 3-5g , Herba Physalis pubescentis 3-6g, Herba Orostachyos 2-4g, Fructus Polygoni Orientalis 2-5g, ulva 2-6g , Caulis Viburni Dilatati 2-5g, Armillaria mella tabescens (Scop.ex Fr.) Sing. 3-6g.
Preferably, the Chinese medicine composition for the treatment of tumor, is made up of the raw material of Chinese medicine of following weight proportioning: Coriolous Dersicolor (Fr.) Quel 7g, Radix Rumicis Patientiae 4g, Herba Selaginellae Involventis 5g, Testa arachidis hypogaeae 10g, Folium Kaki 8g, Radix et Rhizoma Dysosmatis 5g, Folium Fumicis Dentati 3g, Herba Sambuci Chiensis 5g, Fructus Phyllanthi 5g, Herba Lysionoti Pauciflori 5g, chondrus ocellatus Holmes 5g, Pumex 4g, Asparagus toxiformis (Delile) Coll et Harv 6g, Herba Peperomiae Dindygulensis 3g, Herba malachii aquatici 4g , Herba Physalis pubescentis 5g, Herba Orostachyos 4g, Fructus Polygoni Orientalis 3g, ulva 5g , Caulis Viburni Dilatati 3g, Armillaria mella tabescens (Scop.ex Fr.) Sing. 5g.
The pharmacologically active of each raw material of Chinese medicine of the present invention is as follows:
Coriolous Dersicolor (Fr.) Quel is the sporophore of On Polyporaceae Corilus versicolor Quel., sweet, light, is slightly cold, returns liver, spleen, lung meridian, invigorating spleen to remove dampness; Relieving cough and asthma; Heat-clearing and toxic substances removing; Antitumor.Main chronic active hepatitis; Hepatitis interstitialis chronica; Chronic bronchitis; Infantile spasm bronchitis; Laryngopharynx swelling and pain; Kinds of tumors; Rheumatoid arthritis; Leukemia.
Radix Rumicis Patientiae is the root of polygonaceae plant Rumex patientia Linn., bitter, and acid is cold in nature, heat-clearing and toxic substances removing, promoting blood circulation and hemostasis, relieving constipation, parasite killing.Control dysentery, hepatitis, chronic enteritis, traumatic injury, internal hemorrhage, thrombocytopenia, constipation, carbuncle skin ulcer scabies, impetigo, burn.Can promote that bone marrow manufactures platelet, the harmful thrombopoietic various factors of antagonism.
Herba Selaginellae Involventis is the herb of Spikemoss plant Herba Selaginellae Involventis, and flat, taste is micro-sweet, clearing away heat and promoting diuresis, promoting blood circulation and detumescence.For acute infectious hepatitis, the contusion of breast side of body waist, anasarca, thrombocytopenia.
Testa arachidis hypogaeae, the seed coat of pulse family Arachis plant Semen arachidis hypogaeae, sweet, micro-hardship, puckery, flat, hemostasis, dissipating blood stasis, detumescence.For hemophilia, hemophilioid disease, constitutional and secondary thrombocytopenic purpura, hepatopathy hemorrhage, postoperative hemorrhage, cancerous protuberance is hemorrhage, and stomach, intestinal, lung, uterus etc. are hemorrhage.
Folium Kaki is the blade of Ebenaceae plant Fructus Kaki, bitter, cold in nature, returns lung meridian, relieving cough and relieving asthma; Promoting the production of body fluid to quench thirst; Promoting blood circulation and hemostasis.Cure mainly thrombocytopenia; Cough with asthma; Quench one's thirst and various internal hemorrhage; Earn skin ulcer.
Radix et Rhizoma Dysosmatis is rhizome and the root of Berberidaceae plant Radix et Rhizoma Dysosmatis, and sweet, bitter in the mouth is cool, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, dissipating phlegm and resolving masses; Stasis-dispelling and pain-killing; Heat-clearing and toxic substances removing.Main cough; Laryngopharynx swelling and pain; Scrofula; Goiter; Carbuncle; Furuncle; Venom; Traumatic injury harm; Arthromyodynia " Fujian traditional herbal medicine ": " the eliminating stagnation stasis of blood alive, the wart that disappears is detoxified.″
Folium Fumicis Dentati is the leaf of polygonaceae plant rumex dentatus, heat-clearing and toxic substances removing; Killing parasites for relieving itching, cures mainly acute mastitis; Sore swollen toxin; Scabies.
Herba Sambuci Chiensis is the stem and leaf of caprifoliaceae plant Herba Sambuci Chiensis, sweet in the mouth, micro-hardship, and property is put down, and returns Liver Channel, soothing liver and strengthening spleen, blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema.For acute viral hepatitis, oedema due to nephritis, rheumatalgia, dislocation, oedema due to nephritis, beriberi edema, urticaria, injury from falling down, fracture.
Fructus Phyllanthi is the fruit of euphorbia plant Fructus Phyllanthi, sweet, sour, puckery, cool, attaches to the lung and stomach meridians, clearing away heat and cooling blood, promoting digestion and invigorating the stomach, cough-relieving of promoting the production of body fluid.For heat in blood blood stasis, liver-gallbladder disease, dyspepsia, stomachache, cough, laryngalgia, xerostomia.
Herba Lysionoti Pauciflori is the herb of Gesneriaceae Herba Lysionoti Pauciflori, and bitter in the mouth is pungent, and property is put down, and lung heat clearing expectorant, cooling blood for hemostasis, damp eliminatingization is stagnant, removing obstruction in the collateral to relieve pain.Control cough due to lung-heat, spit blood, metrorrhagia and leukorrhagia, bacillary dysentery, infantile malnutrition, rheumatic arthralgia, traumatic injury.
Chondrus ocellatus Holmes is the frond of Shan Zao section plant chondrus ocellatus Holmes, sweet, salty, cold, returns large intestine, stomach warp, removing heat-phlegm; Hard masses softening and resolving.Main consumptive fever hectic fever due to YIN-deficiency; Phlegm-heat cough; Pulmonary tuberculosis; Goiter; Scrofula.
Pumex, for hilum section animal costazia aculeata Canu et Bassler and tumor divide the skeleton of born of the same parents tongue worm etc., salty in the mouth, cold in nature, return lung, kidney channel, removing heat from the lung and dissipating phlegm; Hard masses softening and resolving.Main phlegm-heat cough; Goiter; Skin ulcer swells.
Asparagus toxiformis (Delile) Coll et Harv is the frond of Bai An algae section plant Asparagus toxiformis (Delile) Coll et Harv, pungent, bitter, salty, flat, returns kidney channel, heat-clearing and toxic substances removing; Hard masses softening and resolving.Main scrofula; Goiter.
Herba Peperomiae Dindygulensis is the herb of Piperaceae plant Herba Peperomiae Dindygulensis, pungent, cool, returns lung, spleen, liver, kidney channel, heat-clearing and toxic substances removing; Blood stasis-eliminating and stagnation-dissipating; Inducing diuresis to remove edema.Main lung-heat cough with asthma; Measles; Sore; Cancerous protuberance; Burn and scald; Traumatic injury; Oedema due to nephritis." choosing of Yunnan Chinese herbal medicine ": " eliminating stasis and resolving masses, anticancer.Control gastric cancer, esophageal carcinoma, hepatocarcinoma, breast carcinoma, pulmonary carcinoma.″
Herba malachii aquatici is the herb of pinkwort cattle Herba stellariae mediae, sweet, acid, and property is put down, and returns liver, stomach warp, heat-clearing and toxic substances removing; Dissipating blood stasis for subsidence of swelling.Main dyspnea and cough due to lung-heat; Dysentery; Carbuncle; Hemorrhoid; Toothache; Menoxenia; Infantile malnutrition.
Herba Physalis pubescentis, the herb of plant of Solanaceae Herba Physalis pubescentis, bitter in the mouth, acid, cold in nature, heat clearing away; Diuresis; Removing toxic substances; Detumescence.Main flu; Cough due to lung-heat; Laryngopharynx swelling and pain; Gingival swelling and pain; Jaundice due to damp-heat; Dysentery; Edema; Pyretic stranguria; Pemphigus; Furuncle.Be separated in Herba Physalis pubescentis Herb ethanol extraction and obtain physagulin F (I) and D (II).Compound I test in vitro in 5 kinds of human tumor cell lines (hepatocarcinoma HA22T, cervical cancer HeLa, nasopharyngeal carcinoma KB, rectal cancer Colo-205, pulmonary carcinoma Calu-l) and 3 kinds of animal tumor cell strains (melanoma H1477, larynx epidermal carcinoma Hep-2, glioma 8401) effective, wherein antihepatocarcinoma effect is the strongest, takes second place to HeLa cytosis.Also active anticancer is shown at mouse lymphocyte leukemia P388 in vivo test I.
Herba Orostachyos is the herb of crassulaceae plants Herba Orostachyos or orostachys erudescens etc., acid, bitter, cool, returns liver, lung meridian, cooling blood for hemostasis; Heat-clearing and toxic substances removing; Removing dampness sword skin ulcer.Main haematemesis; Epistaxis; Have blood in stool; Dysentery; Pyretic stranguria; Menoxenia; Furuncle carbuncle; Hemorrhoid; Eczema; Scald; Pneumonia; Hepatitis; Cervical erosion; Chyluria.Modern medicine study proves that Herba Orostachyos can antitumor activity pain.
Fructus Polygoni Orientalis is the fruit of polygonaceae plant Polygonum knotweed, pale persicaria or Folium Salicis Babylonicae knotweed, salty, cool in nature, returns liver, spleen channel, loose blood eliminating mass, removing food stagnancy pain relieving, invigorating spleen to remove dampness, heat-clearing and toxic substances removing; Improving eyesight.For lump in the abdomen mass in the abdomen, goiter swells and ache, and food stagnation does not disappear, epigastric distending pain.
Ulva is the thallus of Ulvaceae plant ulva or U. pertusa, sweet, salty, cold, flat, returns kidney channel, inducing diuresis to remove edema; Softening and eliminating sputum; Heat-clearing and toxic substances removing.Main edema; Deradenoncus; Goiter; Hypertension; Laryngitis; Furuncle; Acute and chronic gastroenteritis; Infantile malnutrition.
Caulis Viburni Dilatati is stem, the leaf of caprifoliaceae plant Caulis Viburni Dilatati, sour in the mouth, cold nature, and dispelling wind detoxifies; Heat-clearing and toxic substances removing; Invigorate blood circulation.Main anemopyretic cold; Furuncle is generated heat; Puerperal cold; Injury and bone fracture.Caulis Viburni Dilatati chrysomelid alcohol extract 50 μ g/ml, have obvious inhibitory action to people's epidermoidoma nasopharyngeal carcinoma (KB) cell in vitro, its suppression ratio is 36.2%.
Armillaria mella tabescens (Scop.ex Fr.) Sing. is the mycelium of Bai Mo section fungus armillariella tabescens, bitter, cold in nature, returns liver, gallbladder meridian, heat-clearing and toxic substances removing.Main acute and chronic cholecystitis; Biliary tract infection; Hepatitis; Appendicitis; Otitis media.From sporophore, be separated the phagocytic function that two kinds of Polysaccharide A T-HW (hot water extract) obtaining and AT-AL (alkaline extraction) can strengthen macrophage in Mice Body, there is antitumor action.
The present invention has following beneficial effect: in Chinese medicine composition of the present invention, each raw material of Chinese medicine is worked in coordination with mutually, play blood circulation promoting and blood stasis dispelling altogether, damp eliminating reduced phlegm, effect of hard masses softening and resolving, heat-clearing and toxic substances removing, and Radix Rumicis Patientiae, Herba Selaginellae Involventis, Testa arachidis hypogaeae, Folium Kaki have good result to the leukopenia after tumor chemoradiotherapy, thrombocytopenia, the immunity of enhancing body while killing tumor cell, ease the pain, all have good therapeutic effect to the tumor that a variety of causes causes, effective percentage is high, has no side effect.
Detailed description of the invention
Be below specific embodiments of the invention, technical scheme of the present invention is described further, but protection scope of the present invention is not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
Embodiment 1
The Chinese medicine composition for the treatment of tumor, is made up of the raw material of Chinese medicine of following weight proportioning: Coriolous Dersicolor (Fr.) Quel 9g, Radix Rumicis Patientiae 3g, Herba Selaginellae Involventis 7g, Testa arachidis hypogaeae 8g, Folium Kaki 5g, Radix et Rhizoma Dysosmatis 8g, Folium Fumicis Dentati 4g, Herba Sambuci Chiensis 6g, Fructus Phyllanthi 4g, Herba Lysionoti Pauciflori 3g, chondrus ocellatus Holmes 8g, Pumex 4g, Asparagus toxiformis (Delile) Coll et Harv 8g, Herba Peperomiae Dindygulensis 4g, Herba malachii aquatici 5g Herba Physalis pubescentis 4g, Herba Orostachyos 3g, Fructus Polygoni Orientalis 4g, ulva 4g , Caulis Viburni Dilatati 5g, Armillaria mella tabescens (Scop.ex Fr.) Sing. 3g.
Embodiment 2
The Chinese medicine composition for the treatment of tumor, is made up of the raw material of Chinese medicine of following weight proportioning: Coriolous Dersicolor (Fr.) Quel 5g, Radix Rumicis Patientiae 4g, Herba Selaginellae Involventis 8g, Testa arachidis hypogaeae 5g, Folium Kaki 10g, Radix et Rhizoma Dysosmatis 3g, Folium Fumicis Dentati 5g, Herba Sambuci Chiensis 6g, Fructus Phyllanthi 3g, Herba Lysionoti Pauciflori 4g, chondrus ocellatus Holmes 3g, Pumex 5g, Asparagus toxiformis (Delile) Coll et Harv 3g, Herba Peperomiae Dindygulensis 4g, Herba malachii aquatici 3g Herba Physalis pubescentis 6g, Herba Orostachyos 2g, Fructus Polygoni Orientalis 5g, ulva 2g , Caulis Viburni Dilatati 4g, Armillaria mella tabescens (Scop.ex Fr.) Sing. 6g.
Embodiment 3
The Chinese medicine composition for the treatment of tumor, is made up of the raw material of Chinese medicine of following weight proportioning: Coriolous Dersicolor (Fr.) Quel 7g, Radix Rumicis Patientiae 4g, Herba Selaginellae Involventis 5g, Testa arachidis hypogaeae 10g, Folium Kaki 8g, Radix et Rhizoma Dysosmatis 5g, Folium Fumicis Dentati 3g, Herba Sambuci Chiensis 5g, Fructus Phyllanthi 5g, Herba Lysionoti Pauciflori 5g, chondrus ocellatus Holmes 5g, Pumex 4g, Asparagus toxiformis (Delile) Coll et Harv 6g, Herba Peperomiae Dindygulensis 3g, Herba malachii aquatici 4g Herba Physalis pubescentis 5g, Herba Orostachyos 4g, Fructus Polygoni Orientalis 3g, ulva 5g , Caulis Viburni Dilatati 3g, Armillaria mella tabescens (Scop.ex Fr.) Sing. 5g.
Embodiment 4
The Chinese medicine composition for the treatment of tumor, is made up of the raw material of Chinese medicine of following weight proportioning: Coriolous Dersicolor (Fr.) Quel 8g, Radix Rumicis Patientiae 5g, Herba Selaginellae Involventis 3g, Testa arachidis hypogaeae 15g, Folium Kaki 7g, Radix et Rhizoma Dysosmatis 7g, Folium Fumicis Dentati 3g, Herba Sambuci Chiensis 7g, Fructus Phyllanthi 4g, Herba Lysionoti Pauciflori 6g, chondrus ocellatus Holmes 7g, Pumex 3g, Asparagus toxiformis (Delile) Coll et Harv 7g, Herba Peperomiae Dindygulensis 5g, Herba malachii aquatici 4g Herba Physalis pubescentis 3g, Herba Orostachyos 3g, Fructus Polygoni Orientalis 2g, ulva 6g , Caulis Viburni Dilatati 2g, Armillaria mella tabescens (Scop.ex Fr.) Sing. 4g.
Clinical data
Physical data: accept for medical treatment altogether tumor patient 780 example, wherein male 412 example, women 368 example, age 13-78 year, 48 years old mean age.
Therapeutic Method: Chinese medicine composition of the present invention is decocted in water for oral dose, every day potion, one day twice, sooner or later sub-service one month was a course for the treatment of.
Curative effect judging standard:
Effective: cancerous cell reduces, immunity improves, energetic, painless;
Effective: cancerous cell is inhibited substantially, immunity increases, and spirit is not good enough, pain relief;
Invalid: cancerous cell is constant, mental status is poor, still has pain, and symptom is obvious.
Therapeutic outcome: through the treatment of 1-6 the course for the treatment of, result statistics is as follows:
Number of cases Effective Effectively Invalid Obvious effective rate Total effective rate
Pulmonary carcinoma 167 135 30 2 80.83% 98.80%
Gastric cancer 106 95 8 3 89.62% 97.17%
Lymphatic cancer 64 42 20 2 65.63% 96.88%
Hepatocarcinoma 97 69 25 3 71.13% 96.91%
Esophageal carcinoma 84 72 12 0 85.71% 100.0%
Breast carcinoma 75 64 11 0 85.33% 100.0%
Rectal cancer 98 75 21 2 76.53% 97.96%
Cervical cancer 89 68 21 0 76.40% 100.0%
While Chinese medicine composition of the present invention kills tumor cell, the immunity of enhancing body, eases the pain, and all have good therapeutic effect to the tumor that a variety of causes causes, effective percentage is high, alleviates patient suffering, extends the life of patient.
Model case 1
Chen, man, 49 years old, occur cough and expectoration in February, 2012 without obvious inducement, local hospital is with common cold treatment without alleviation, and hemoptysis appears in March 31, admission examination display bottom right lung irregular masses, RHLN and Intrahepatic metastasis.For clear and definite cell type, under color ultrasound guidance, do aspiration biopsy to bottom right lung neoplasms, pathological replacement is low differentiated squamous-cell carcinomas.Obviously alleviate by pain after two courses for the treatment of of traditional Chinese medicine composition for treating of the present invention, mass reduction, after three courses for the treatment of of continual cure, routine blood test and hepatic and renal function recover normal, and status of patient is good so far.
Model case 2
Hole, female, 55 years old, occur that feed is choked with sobs without obvious inducement in July, 2011, feed be dry, hard food time obvious, soft diet liquid food can be entered, without acid regurgitation, vomiting, without heating, spits blood and melena, it is invalid after Supporting Therapy March to the ill to give with " esophagitis " in hospital, and in November, 2011 feed sense of choking with sobs comparatively before increases the weight of.The contrast examination of row esophageal barium meal is shown: esophago mesomere cancer (infiltrative type).Good with patient's spirit after three courses for the treatment of of traditional Chinese medicine composition for treating of the present invention, diet, sleep, defecation is normal, conscious meal situation comparatively before improve, occasionally have esophagus pain after feed.Take a turn for the better more to some extent before the barivm meal fluoroscopy (screem) of check esophagus points out Esophageal Middle Segment pathological changes comparatively.
Model case 3
Jiang, man, 58 years old, 08 year because of epigastrium dull pain discomfort, poor appetite, become thin, liver pain, epigastrium lays one's hand on enclosed mass and comes to go to a doctor for 15 days, alpha-fetoprotein (AFP) 12500ng, B ultrasonic, CT examination display " left Liver masses ", row " left intrahepatic leaf excision ", micronodular cirrhosis is seen in art, tumor is positioned at left half intrahepatic leaf, about 9 × 7cm size, and pathological replacement is: " hepatocellular carcinoma; penetrate Glisson's capsule, Ink vessel transfusing is looked into and seen cancer embolus ".Postoperative traditional Chinese medicine composition for treating of the present invention three months alpha-fetoproteins are down to normally, leave hospital and do not recur so far.
Model case 4
Revive so-and-so, female, 33 years old, before being admitted to hospital, occurring diarrhoea more than February, average every day more than 10 times, occurred kermesinus hemafecia before January without obvious inducement, without difficult defecation, defecation pain, nothing dizziness, heating, without stomachache, abdominal distention and other discomfort.Once scorching at outer court's diagnosis intestinal before being admitted to hospital, fail to respond to any medical treatment.Colonoscopy: apart from anus 8 centimetres of proctostenosis, visible ulcer type swells thing.Biopsies diagnosis: rectum signet-ring cell carcinoma.With after two courses for the treatment of of traditional Chinese medicine composition for treating of the present invention, swollen thing reduces, and diarrhoea number of times obviously reduces, and continual cure two patient's defecation course for the treatment of is normal, and swollen thing disappears recovery from illness.
Model case 5
Wu, man, 47 years old, patient was because of epigastric distending pain, and more than loss of appetite half a year, once melena repeatedly, because a large amount of hematemesis is once admitted to hospital.By barium meal and gastroscopy, and through pathological diagnosis be: gastric antrum portion adenocarcinoma.Suggestion excision.Because patient and family members fear operation, leave hospital after being introduced, take a turn for the better by symptom after the course for the treatment of of traditional Chinese medicine composition for treating of the present invention, continual cure three the clinical symptoms course for the treatment of disappears substantially, advises its regular further consultation.

Claims (2)

1. treat the Chinese medicine composition of tumor, it is characterized in that, be made up of the raw material of Chinese medicine of following weight proportioning: Coriolous Dersicolor (Fr.) Quel 5-9g, Radix Rumicis Patientiae 3-5g, Herba Selaginellae Involventis 3-8g, Testa arachidis hypogaeae 5-15g, Folium Kaki 5-10g, Radix et Rhizoma Dysosmatis 3-8g, Folium Fumicis Dentati 3-5g, Herba Sambuci Chiensis 5-7g, Fructus Phyllanthi 3-5g, Herba Lysionoti Pauciflori 3-6g, chondrus ocellatus Holmes 3-8g, Pumex 3-5g, Asparagus toxiformis (Delile) Coll et Harv 3-8g, Herba Peperomiae Dindygulensis 3-5g, Herba malachii aquatici 3-5g , Herba Physalis pubescentis 3-6g, Herba Orostachyos 2-4g, Fructus Polygoni Orientalis 2-5g, ulva 2-6g , Caulis Viburni Dilatati 2-5g, Armillaria mella tabescens (Scop.ex Fr.) Sing. 3-6g.
2. the Chinese medicine composition for the treatment of tumor as claimed in claim 1, is characterized in that, be made up of: Coriolous Dersicolor (Fr.) Quel 7g the raw material of Chinese medicine of following weight proportioning, Radix Rumicis Patientiae 4g, Herba Selaginellae Involventis 5g, Testa arachidis hypogaeae 10g, Folium Kaki 8g, Radix et Rhizoma Dysosmatis 5g, Folium Fumicis Dentati 3g, Herba Sambuci Chiensis 5g, Fructus Phyllanthi 5g, Herba Lysionoti Pauciflori 5g, chondrus ocellatus Holmes 5g, Pumex 4g, Asparagus toxiformis (Delile) Coll et Harv 6g, Herba Peperomiae Dindygulensis 3g, Herba malachii aquatici 4g , Herba Physalis pubescentis 5g, Herba Orostachyos 4g, Fructus Polygoni Orientalis 3g, ulva 5g , Caulis Viburni Dilatati 3g, Armillaria mella tabescens (Scop.ex Fr.) Sing. 5g.
CN201410683226.6A 2014-11-25 2014-11-25 Traditional Chinese medicinal composition for treating tumors Pending CN104367702A (en)

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Publication number Priority date Publication date Assignee Title
CN106138726A (en) * 2016-07-29 2016-11-23 广州加原医药科技有限公司 A kind of Chinese medicine composition of reverse multiple drug resistance of tumor
AU2016415998B2 (en) * 2016-07-29 2022-01-13 Commonwealth Scientific And Industrial Research Organisation Growth performance improvements in pasture and feedlot systems
WO2022129453A1 (en) 2020-12-18 2022-06-23 Universite De Perpignan Via Domitia (Upvd) Antibacterial and antiparasitic compound

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* Cited by examiner, † Cited by third party
Title
吕兰熏: "中药升高白细胞的研究", 《陕西中医学院学报》 *
李艳: "扶正祛邪化毒法在肿瘤治疗中的应用", 《中医药临床杂志》 *
王仁: "《萨克药志 第三册》", 31 August 2018, 新疆科学技术出版社 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106138726A (en) * 2016-07-29 2016-11-23 广州加原医药科技有限公司 A kind of Chinese medicine composition of reverse multiple drug resistance of tumor
AU2016415998B2 (en) * 2016-07-29 2022-01-13 Commonwealth Scientific And Industrial Research Organisation Growth performance improvements in pasture and feedlot systems
WO2022129453A1 (en) 2020-12-18 2022-06-23 Universite De Perpignan Via Domitia (Upvd) Antibacterial and antiparasitic compound
FR3117734A1 (en) 2020-12-18 2022-06-24 Universite De Perpignan Via Domitia (Upvd) Antibacterial and antiparasitic compound

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Application publication date: 20150225