CN104338110A - 一种治疗手足麻木的药物及其制备方法 - Google Patents

一种治疗手足麻木的药物及其制备方法 Download PDF

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CN104338110A
CN104338110A CN201410612010.0A CN201410612010A CN104338110A CN 104338110 A CN104338110 A CN 104338110A CN 201410612010 A CN201410612010 A CN 201410612010A CN 104338110 A CN104338110 A CN 104338110A
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张怀英
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Abstract

本发明公开了一种治疗手足麻木的药物及其制备方法，它主要是由川牛膝、五加皮、秦艽、伸筋草、桂枝、木瓜、干姜、千年健、赤芍、透骨草按一定重量配比制备而成，本发明药物具有祛风除湿，温经散寒，活血通络，追毒定痛的功能，用于治疗手足麻木见效快，疗程短，不复发。

Description

一种治疗手足麻木的药物及其制备方法
技术领域
本发明涉及一种治疗手足麻木的药物及其制备方法，属中药领域。
技术背景
手足麻木是人体在主动或被动下麻木，有时静止时稍重，或在活动加剧，严重时活动受限，生活不能自理，多与肝，肾，心，脾有密切关系，以及六淫：风、寒、暑、湿、燥、火等邪气闭阻经络，影响气血运行，导致肢体、筋骨、关节、肌肉等发生疼痛、酸楚、麻木，或关节屈伸不利、僵硬、肿大、变形等症状的一种慢性疾病。轻者病在四肢关节肌肉，重者涉及脏腑，尤其是心脏。目前，由于西药无法有效治疗手足麻木，且长期服用西药有较多副作用，因此，人们对有效治疗手足麻木的中药存在很大的需求。
发明内容
目前还没有发现关于治疗手足麻木的中药的有关报道，本发明人经过反复的试验和验证，终于找到了有效治疗手足麻木的药物，从而完成了本发明。
本发明的目的就是提供一种能够有效治疗手足麻木的组合药物。
本发明的另一个目的就是提供了该组合药物的制备方法。
本发明药物是选择川牛膝、五加皮、秦艽、伸筋草、桂枝、木瓜、干姜、千年健、赤芍、透骨草、肉桂、羌活、独活、乳香、没药、当归、苍术、白芥子、川乌头、草乌头、半夏、天南星药物进行组合的，将这些药物组合使得各药物功效产生协同作用，从而能够有效治疗手足麻木的复发。其中选用川牛膝是因为其性味平，味苦微苦，无毒，入肝、肾二经，有祛风，利湿，通经，活血的功能，治风湿腰膝疼痛，脚痿筋挛，血淋，尿血，妇女经闭，癥瘕。选用五加皮是因为其性味辛，温，入肝、肾经，有祛风湿，壮筋骨，活血去瘀的功能，治风寒湿痹，筋骨挛急，腰痛，阳痿，脚弱，小儿行迟、水肿，脚气，疮疽肿毒，跌打劳伤。选用秦艽是因为其性味苦辛，平，入肝、胃、胆经，有祛风除湿，和血舒筋，清热利尿的功能，治风湿痹痛，筋骨拘挛，黄疸，便血，骨蒸潮热，小儿疳热，小便不利。选用伸筋草是因为其性味苦辛，温，入肝、胃、肾三经，有祛风散寒，除湿消肿，舒筋活血的功能，治风寒湿痹，关节酸痛，皮肤麻木，四肢软弱，水肿，跌打损伤。选用桂枝是因为其性味辛甘，温，入膀胱、心、肺经，有发汗解肌，温经通脉的功能，治风寒表证，肩背肢节酸疼，胸痹痰饮，经闭癥瘕。选用木瓜是因为其性味酸，温，入肝、脾经，有平肝和胃，去湿舒筋的功能，治吐泻转筋，湿痹，脚气，水肿，痢疾。选用干姜是因为其性味辛，热，入脾、胃、肺经，有温中逐寒，回阳通脉的功能，治心腹冷痛，吐泻，肢冷脉微，寒饮喘咳，风寒湿痹，阳虚吐、衄、下血。选用千年健是因为其性味苦、辛，温，归肝、肾经，有祛风湿，健筋骨的功能，治风寒湿痹，腰膝冷痛，下肢拘挛麻木。选用赤芍是因为其性味苦，微寒，归肝经，有清热凉血，散瘀止痛的功能，治温毒发狂，吐血衄血，目赤肿痛，肝郁胁痛，经闭痛经，癎瘕腹痛，跌扑损伤，痈肿疮疡。选用透骨草是因为其性味辛温，有祛风，除湿，舒筋，活血，止痛的功能，治风湿痹痛，筋骨挛缩，疮癣肿毒。选用肉桂是因为其性味辛甘，热，入肾、脾、膀胱经，有补元阳，暖脾胃，除积冷，通血脉的功能，治命门火衰，肢冷脉微，亡阳虚脱，腹痛泄泻，寒疝奔豚，腰膝冷痛，经闭癥瘕，阴疽，流注，及虚阳浮越，上热下寒。选用羌活是因为其性味辛苦，温，入膀胱、肾经，有散表寒，祛风湿，利关节的功能，治感冒风寒，头痛无汗，风寒湿痹，项强筋急，骨节酸疼，风水浮肿，痈疽疮毒。选用独活是因为其性味辛苦，温，入肾、膀胱经，有祛风，胜湿，散寒，止痛的功能，治风寒湿痹，腰漆酸痛，手脚挛痛，慢性气管炎，头痛，齿痛。选用乳香是因为其性味辛苦，温，入心、肝、脾经，有调气活血，定痛，追毒的功能，治气血凝滞，心腹疼痛，痈疮肿毒，跌打损伤，痛经，产后瘀血刺痛。选用没药是因为其性味苦，平，入肝经，有散血去瘀，消肿定痛的功能，治跌损，金疮，筋骨，心腹诸痛，癥瘕，经闭，痈疽肿痛，痔漏，目障。选用当归是因为其性味甘辛，温，入心、肝、脾经，有补血和血，调经止痛，润燥滑肠的功能，治月经不调，经闭腹痛，癥瘕结聚，崩漏，血虚头痛，眩晕，痿痹，肠燥难便，赤痢后重，痈疽疮疡，金疮，跌扑损伤。选用苍术是因为其性味辛苦，温，入脾、胃经，有健脾，燥湿，解郁，辟秽的功能，治湿盛困脾，倦怠嗜卧，脘痞腹胀，食欲不振，呕吐，泄泻，痢疾，疟疾，痰饮，水肿，时气感冒，风寒湿痹，足痿，夜盲。选用白芥子是因为其性味辛，温，入肺、胃经，有利气豁痰，温中散寒，通络止痛的功能，治痰饮咳喘，胸胁胀满疼痛，反胃呕吐，中风不语，肢体痹痛麻木，脚气，阴疽，肿毒，跌打肿痛。选用川乌头，异名川乌，其性味辛，热，有毒，入脾、命门二经，有祛寒湿，散风邪，温经，止痛的功能，治风寒湿痹，历节风痛，四肢拘挛，半身不遂，头风头痛，心腹冷痛，阴疽肿毒。选用草乌头，异名草乌，其性味辛，热，有毒，入肝、脾、肺经，有搜风胜湿，散寒止痛，开痰，消肿的功能，治风寒湿痹，中风瘫痪，破伤风，头风，脘腹冷痛，痰癖，气块，冷痢，喉痹，痈疽，疔疮，瘰疬。选用半夏是因为其性味辛，温，有毒，入脾、胃经，有燥湿化痰，降逆止呕，消痞散结的功能，治湿痰冷饮，呕吐，反胃，咳喘痰多，胸膈胀满，痰厥头痛，头晕不眠，外消痈肿。选用天南星是因为其性味苦辛，温，有毒，入肺、肝、脾经，有燥湿化痰，祛风定惊，消肿散结的功能，治中风痰瘰，口眼喎斜，半身不遂，癫癎，惊风，破伤风，风痰眩晕，喉痹，瘰疬，痈肿，跌扑损伤，蛇虫咬伤。选用花椒是因为其性味辛，温，有毒，入脾、肺、肾经，有温中散寒，除湿，止痛，杀虫，解鱼腥毒，治积食停饮，心腹冷痛，呕吐，噫呃，咳嗽气逆，风寒湿痹，泄泻，痢疾，疝痛，齿痛，蛔虫病，蛲虫病，阴痒，疮疥。选用野葱是因为其性温，味辛，有发汗，散寒，消肿，健胃的功能，治伤风感冒，头痛发烧，腹部冷痛，消化不良，能接骨。选用艾叶是因为其性味苦辛，温，入脾、肝、肾经，有理气血，逐寒湿；温经，止血，安胎的功能，治心腹冷痛，泄泻转筋，久痢，吐衄，下血，月经不调，崩漏，带下，胎动不安，痈疡，疥癣。选用桑枝是因为其性味苦，平，入肝经，有祛风湿，利关节，行水气的功能，治风寒湿痹，四肢拘挛，脚气浮肿，肌体风痒。麦麸为小麦制面后剩余的麦皮。
本发明选用伸筋草为君药，千年健、透骨草为臣药，天南星为佐药，独活为使药，与上述药物组合，共同制成治疗手足麻木的组合药物。
具体实施方式
本发明组合的药物用量也是发明人经过大量摸索总结得出的，各组分的用量在下述重量范围内都具有较好疗效
川牛膝    35-45克         五加皮        35-45克      秦  艽        35-45克
伸筋草    35-45克         桂  枝        25-35克      木  瓜        25-35克
干  姜     25-35克         千年健        35-45克      赤  芍        25-35克
透骨草    35-45克         肉  桂        15-25克      羌  活        30-40克
独  活     25-35克         乳  香        30-40克      没  药        30-40克
当  归     25-35克         苍  术        30-40克      白芥子       25-35克
川乌头    15-25克         草乌头        15-25克      半  夏        20-35克
天南星    25-35克         花  椒        25-35克      野  葱        35-45克
艾  叶     35-45克         桑  枝        35-45克      醋               1450-1550克
麦  麸     1450-1550克
优选用量为
川牛膝    40克              五加皮        40克           秦  艽        40克
伸筋草    40克              桂  枝        30克           木  瓜        30克
干  姜     30克              千年健        40克           赤  芍        30克
透骨草    40克              肉  桂        20克           羌  活        35克
独  活     30克              乳  香        35克           没  药        35克
当  归     30克              苍  术        35克           白芥子       30克
川乌头    20克              草乌头        20克           半  夏        25克
天南星    30克              花  椒        30克           野  葱        40克
艾  叶     40克              桑  枝        40克           醋               1500克
麦  麸     1500克                                                
本发明药物的制备方法如下
一、备料
1、川牛膝：拣去杂质，晾干；
2、五加皮：拣净杂质，用水洗净，稍润后，切片，干燥；
3、秦艽：拣去杂质，除去芦头，稍浸，润透切片，晒干；
4、伸筋草：筛去灰屑，拣净杂质，切成小段；
5、桂枝：用水稍浸泡，捞出，闷润至透，切片，晾干，筛去屑；
6、木瓜：清水洗净，稍浸泡，闷润至透，置蒸笼内蒸熟，趁热切片，日晒夜露，以由红转紫黑色为止；
7、干姜：拣净杂质，用水浸泡3—6小时，捞出，闷润后切片或切成小方块，晒干；
8、千年健：除去杂质，洗净，润透，切薄片，干燥，筛去碎屑；
9、赤芍：取原药材，除去杂质，大小分档，洗净，润透，切薄片，干燥，筛去碎屑；
10、透骨草：拣净杂质，切段；
11、肉桂：拣净杂质，刮去粗皮，用温开水浸润片刻，切片，晾干；
12、羌活：拣去杂质，洗净，润透，切片，晾干；
13、独活：拣去杂质，分开大小个，洗净，润透后切片，干燥；
14、乳香：拣去砂子杂质；
15、没药：拣去杂质，打成碎块；
16、当归：拣去杂质，洗净，闷润，稍晾，切片晒干；
17、苍术：拣去杂质，用水泡至七、八成透，捞出，润透后切片，晒干；
18、白芥子：原药簸尽杂质，炒至深黄色，微有香气即得；
19、川乌头：拣去杂质，洗净灰屑，晒干；
20、草乌头：取原药材，除去杂质，洗净，干燥，用时捣碎；
21、半夏：拣去杂质，筛去灰屑；
22、天南星：拣去杂质，洗净灰屑，晒干；
23、花椒：除去果柄及种子，置锅内炒至发响，油出，取出，放凉；
24、野葱：5-6月采收，鲜用，或切段晒干；
25、艾叶：拣去杂质，去梗，筛去灰屑；
26、桑枝：拣去杂质，洗净，用水浸泡，润透后，切片，晒干。
二、制备
1、将所述重量的川牛膝、五加皮、秦艽、伸筋草、桂枝、木瓜、干姜、千年健、赤芍、透骨草、肉桂、羌活、独活、乳香、没药、当归、苍术、白芥子、川乌头、草乌头、半夏、天南星、花椒、野葱、艾叶、桑枝捣碎成豆粒大的碎末，用醋浸泡2小时后，将醋倒出。
2、将所述重量的麦麸用倒出的醋搅拌均匀。
3、将浸泡好的药物与拌醋的麦麸混合搅拌均匀后，放入铁锅内炒热，注意炒热的温度以不烫伤皮肤为准。
4、将炒热的药物分装入三个布袋内备用。
本发明药物具有祛风除湿，温经散寒，通络活血，追毒定痛的功效，治疗手足麻木见效快、疗程短，不复发。
以下通过试验例来进一步阐述本发明药物的有益效果。
[试验例1] 本发明药物的临床观察资料
1、一般资料
收治门诊患者45例。
2、诊断标准
临床表现
临床症状表现即为诊断基础，如肢体关节，肌肉疼痛，麻木不仁，曲伸不利，疼痛游走不适。甚或关节剧痛，肿大，变形，强硬，僵直不得屈伸。
3、治疗方法
将炒热的药袋放于患处贴敷，如治疗下肢膝盖时，可将药袋分别置于膝盖的上下两侧，另一个药袋可轮流替换，药袋口不要扎的太紧，使药袋和肌体接触面加大，把患肢膝盖上下包严，另在上面覆盖棉衣，直至熥出汗，每天2次，连续治疗3个疗程，每个疗程7天。
4、疗效评定标准
显效：手足麻木消除，痊愈，观察半年后无复发； 
好转：手足麻木症状明显好转，麻木感逐渐减轻； 
无效：症状无改善，达不到好转标准者。
5、治疗结果（见下表）
在上述的治疗中，用本发明药物治疗手足麻木患者45例，结果显效42例，显效率为93.33%，好转2例，好转率为4.45%，无效1例，总有效率为97.78%。

Claims (3)

1.一种治疗手足麻木的药物, 其特征在于：它是由下列重量范围内的原料药制成：
川牛膝 35-45克   五加皮 35-45克   秦  艽 35-45克
伸筋草 35-45克   桂  枝 25-35克   木  瓜 25-35克
干  姜 25-35克   千年健 35-45克   赤  芍 25-35克
透骨草 35-45克   肉  桂 15-25克   羌  活 30-40克
独  活 25-35克   乳  香 30-40克   没  药 30-40克
当  归 25-35克   苍  术 30-40克   白芥子 25-35克
川乌头 15-25克   草乌头 15-25克   半  夏 20-35克
天南星 25-35克   花  椒 25-35克   野  葱 35-45克
艾  叶 35-45克   桑  枝 35-45克   醋  1450-1550克
麦  麸 1450-1550克。
2.根据权利要求1所述的药物，其中各原料药的用量为：
川牛膝 40克   五加皮 40克   秦  艽 40克
伸筋草 40克   桂  枝 30克   木  瓜 30克
干  姜 30克   千年健 40克   赤  芍 30克
透骨草 40克   肉  桂 20克   羌  活 35克
独  活 30克   乳  香 35克   没  药 35克
当  归 30克   苍  术 35克   白芥子 30克
川乌头 20克   草乌头 20克   半  夏 25克
天南星 30克   花  椒 30克   野  葱 40克
艾  叶 40克   桑  枝 40克   醋  1500克
麦  麸 1500克。
3.根据权利要求1或2所述药物的制备方法，它包括下列步骤：
（一）备料
（1）川牛膝：拣去杂质，晾干；
（2）五加皮：拣净杂质，用水洗净，稍润后，切片，干燥；
（3）秦艽：拣去杂质，除去芦头，稍浸，润透切片，晒干；
（4）伸筋草：筛去灰屑，拣净杂质，切成小段；
（5）桂枝：用水稍浸泡，捞出，闷润至透，切片，晾干，筛去屑；
（6）木瓜：清水洗净，稍浸泡，闷润至透，置蒸笼内蒸熟，趁热切片，日晒夜露，以由红转紫黑色为止；
（7）干姜：拣净杂质，用水浸泡3—6小时，捞出，闷润后切片或切成小方块，晒干；
（8）千年健：除去杂质，洗净，润透，切薄片，干燥，筛去碎屑；
（9）赤芍：取原药材，除去杂质，大小分档，洗净，润透，切薄片，干燥，筛去碎屑；
（10）透骨草：拣净杂质，切段；
（11）肉桂：拣净杂质，刮去粗皮，用温开水浸润片刻，切片，晾干；
（12）羌活：拣去杂质，洗净，润透，切片，晾干；
（13）独活：拣去杂质，分开大小个，洗净，润透后切片，干燥；
（14）乳香：拣去砂子杂质；
（15）没药：拣去杂质，打成碎块；
（16）当归：拣去杂质，洗净，闷润，稍晾，切片晒干；
（17）苍术：拣去杂质，用水泡至七、八成透，捞出，润透后切片，晒干；
（18）白芥子：原药簸尽杂质，炒至深黄色，微有香气即得；
（19）川乌头：拣去杂质，洗净灰屑，晒干；
（20）草乌头：取原药材，除去杂质，洗净，干燥，用时捣碎；
（21）半夏：拣去杂质，筛去灰屑；
（22）天南星：拣去杂质，洗净灰屑，晒干；
（23）花椒：除去果柄及种子，置锅内炒至发响，油出，取出，放凉；
（24）野葱：5-6月采收，鲜用，或切段晒干；
（25）艾叶：拣去杂质，去梗，筛去灰屑；
（26）桑枝：拣去杂质，洗净，用水浸泡，润透后，切片，晒干；
（二）制备
（1）将所述重量的川牛膝、五加皮、秦艽、伸筋草、桂枝、木瓜、干姜、千年健、赤芍、透骨草、肉桂、羌活、独活、乳香、没药、当归、苍术、白芥子、川乌头、草乌头、半夏、天南星、花椒、野葱、艾叶、桑枝捣碎成豆粒大的碎末，用醋浸泡2小时后，将醋倒出；
（2）将所述重量的麦麸用倒出的醋搅拌均匀；
（3）将浸泡好的药物与拌醋的麦麸混合搅拌均匀后，放入铁锅内炒热；
（4）将炒热的药物分装入三个布袋内。
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105169246A (zh) * 2015-09-11 2015-12-23 徐学军 一种治疗手足麻木的药剂
CN105362913A (zh) * 2015-12-15 2016-03-02 张朝兰 一种治疗呃逆的药物及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张义尚: "《中医薪传》", 31 May 2012 *
苏定冯: "《家庭用药指导》", 30 November 2001 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105169246A (zh) * 2015-09-11 2015-12-23 徐学军 一种治疗手足麻木的药剂
CN105362913A (zh) * 2015-12-15 2016-03-02 张朝兰 一种治疗呃逆的药物及其制备方法

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