CN104324214B - Halitosis navel paster and preparation method thereof - Google Patents

Halitosis navel paster and preparation method thereof Download PDF

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CN104324214B
CN104324214B CN201410698466.3A CN201410698466A CN104324214B CN 104324214 B CN104324214 B CN 104324214B CN 201410698466 A CN201410698466 A CN 201410698466A CN 104324214 B CN104324214 B CN 104324214B
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parts
halitosis
water
navel
navel paster
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CN104324214A (en
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姚睿
王志立
邓太秀
刘海育
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HENAN HEXIN HENGDA INDUSTRIAL Co Ltd
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HENAN HEXIN HENGDA INDUSTRIAL Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967Lilium, e.g. tiger lily or Easter lily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention relates to a kind of halitosis navel paster and preparation method thereof, medicament composition of layer is 35 parts of peppermint, 13 parts of borneol, 13 parts of rosemary, 13 parts of cloves, 15 parts of Bergamot, 13 parts of lily, 10 20 parts of water-absorbing resin, 35 parts of disodium ethylene diamine tetraacetate, 50 60 parts of pure water will be added after each composition is mixed above, stir, it is coated on lining cloth layer, plaster is made.The halitosis navel paster of the present invention is made of pure Chinese medicine, and rationally, drug effect is complementary for compatibility;Method is simple, using safety, in the absence of any side effect.The patch is attached at navel when using, in the absence of any side effect, curative effect is fast, the therapeutic modality of this inner disease outer treat, can reach the purpose of the obstinate halitosis persistent ailment for the treatment of, easily be easily accepted by the patient.

Description

Halitosis navel paster and preparation method thereof
Technical field
The present invention relates to a kind of medicament except halitosis, more particularly to a kind of halitosis navel paster and preparation method thereof.
Background technology
With social progress and the popularization of hygienic knowledge, most people has formed good oral sanitary habit, but still There are many people not break away from the puzzlement of halitosis, have a strong impact on daily life.
For medical angle, halitosis is substantially general disease or a kind of sign of local disease, especially ability to speak disease Common clinical symptoms in disease.Because of the halitosis caused by general disease, patient tends to actively seek medical advice, and is eliminated halitosis; Because of the halitosis caused by ability to speak disease, because symptom is not obvious, patient payes attention to not enough, and majority is not sought medical advice actively, therefore the halitosis time It is longer.In general, easily causing halitosis and easily mainly having dental caries tooth by the ability to speak disease that people ignore(It is commonly called as decayed tooth), periodontal Disease.Science is own to be proved, periodontitis, the generation of halitosis are largely by bacterial mouth disease phenomenon.In addition, stomach Intestines problem such as peptic ulcer, chronic gastritis etc., breathing problem such as bronchitis, nasosinusitis, sphagitis, tonsillitis Deng all may be with halitosis phenomenon.
Existing various preparation lozenges, chewing gum, oral granule etc., have certain curative effect to alleviating halitosis, but simultaneously Oral cavity partial can not be made to keep sufficiently long effective antibacterial time, it is impossible to halitosis is fundamentally removed, to produce good treatment Effect.
The content of the invention
The purpose of the present invention is:Overcome the deficiencies in the prior art there is provided a kind of inner disease outer treat, method it is simple, using safety Halitosis navel paster and preparation method.
Technical scheme:
A kind of halitosis navel paster, includes the lining cloth layer of upper strata off-style paper layer, middle medicament layer and bottom, the composition of medicament layer For:3-5 parts of peppermint, 1-3 parts of borneol, 1-3 parts of rosemary, 1-3 parts of cloves, 1-5 parts of Bergamot, 1-3 parts of lily, water suction tree 10-20 parts of fat, 3-5 parts of disodium ethylene diamine tetraacetate.
The water-absorbing resin is one kind in polyacrylic, polyethenol series, polyoxyethylene system resin.
The preparation method of the halitosis navel paster:3-5 parts of peppermint, 1-3 parts of borneol, 1-3 parts of rosemary, cloves 1- are weighed respectively 3 parts, 1-5 parts of Bergamot, 1-3 parts of lily it is possible to additionally incorporate 10-20 parts of water-absorbing resin, 3-5 parts of disodium ethylene diamine tetraacetate, 50-60 part of pure water is added after mixing, is stirred, is coated on lining cloth layer, then cuts blocking, plaster is made.
The effect of each composition in medicament layer:
Menthol:It is antipruritic for local analgesia, headache, dizziness, bite by mosquitos;Collunarium, which is used to catch cold, has a stuffy nose, suction or spray Mist is used for sphagitis;Orally can be with stomach invigorating;There is the effect such as antipruritic, analgesic, anti-corrosion, stimulation, anesthesia, refrigerant and anti-inflammatory, head can be controlled Bitterly, neuralgia, itch and respiratory inflammation, atrophic rhinitis, celostomia etc..
Borneol:Lead to all keys, dissipate stagnated fire, go screen improving eyesight, swelling and pain relieving;Control apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm fan, gas Close deafness, larynx numbness, aphtha, carbuncle swells, hemorrhoid etc..
Rosemary:Acted on tranquilizing and allaying excitement, restoring consciouness, have certain curative effect to indigestion and stomachache.
Bergamot:Have soothing liver-qi stagnation, eliminating dampness and eliminating phlegm, qi-regulating and middle effect, be usually used in stagnation of QI due to depression of the liver, the taste stagnation of the circulation of vital energy and Phlegm obstructing lung etc. is demonstrate,proved.
Cloves:For deficiency-cold in spleen and stomach, hiccup vomiting, deficiency of food vomiting and diarrhoea, trusted subordinate's crymodynia and impotence due to deficiency of the kidney etc..
Lily:It is sweet, tremble with fear, the thoughts of returning home, lung channel;Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing;The nutrition wherein needed containing abundant human body into Point, stomach invigorating, dampness removing disperse accumulations, antitoxic heart-soothing and sedative, lung can be moistened by often eating lily, antipyretic, eliminate drying thirsty.
The pure and fresh restoring consciouness of menthol, borneol in mentioned component, treats halitosis;Rosemary tranquilizing the mind and aiding digestion;Bergamot, cloves are soothing the liver Qi-regulating, coordinates other each compositions, and drug effect is complementary, compatibility science.
Menthol applies Shenque, people will not taste yin excess, implication can slowly become pure and fresh.Peppermint fragrance is pungent cool, and pungent cool energy is clear Heat, it is fragrant then walk to alter upwards.The pungent cool gas of peppermint is together upward with the internal heat of the gate of vitality, runs in stomach, plays its heat-clearing Effect, stomach fire is gone down clearly, and halitosis is naturally also removed.Peppermint can also allow people's breath freshening, clearheaded, because thin The fragrant performance of lotus continuously upwards is walked to alter, and stomach energy can be removed in stomach by reaching, moreover it is possible to continued up arrival in the mouth, made in the mouth Breath is pure and fresh.
The umbilical compress therapy of the present invention, is that the medicine that will be prepared is spread on patient's navel, from umbilical region administration, is conducive to medicine to return Through making drug effect follow through guiding drugs to illness station, adjusting negative and positive of qi and blood, to drive away disease and evil, building up healthful vital energy, have to disease preventing and treating particularly significant Effect.In terms of modern medical theory, navel skin is most thin, is easier than other cutaneous penetration positions.Meanwhile, peritonaeum under navel There is abundant blood vessel, medicine is easier to absorb, and can quickly enter blood circulation, and bioavilability is high, and the efficacy of a drug can guide drugs to illness station, reach To the purpose for the treatment of.In addition, umbilical region nerve ending is abundant, hyperesthesia presses stimulation, moreover it is possible to adjust neuroendocrine system by medicine System, improves the function of each internal organs.Umbilical compress therapy is simple and easy to do, can both mitigate toxic side effect of the medicine to liver kidney, can exempt again Stimulation of the endo-medicine to intestines and stomach, the acceptant , Te Do of patient are adapted to the difficult infant and the elderly of medication.
The halitosis navel paster of the present invention, is made, each components compatibility is reasonable of pure Chinese medicine composition;Method is simple, uses peace Entirely, the patch is attached at navel when using, in the absence of any side effect.A daily note, 7 days is a course for the treatment of, general 3 The course for the treatment of is cured, and curative effect is fast.The therapeutic modality of this inner disease outer treat, can reach the purpose of the obstinate halitosis persistent ailment for the treatment of, easily by patient Received.
Embodiment
Embodiment one:A kind of halitosis navel paster, includes the lining cloth layer structure of upper strata off-style paper layer, middle medicament layer and bottom Into the medicament composition of layer is:
3-5 parts of peppermint, 1-3 parts of borneol, 1-3 parts of rosemary, 1-3 parts of cloves, 1-5 parts of Bergamot, 1-3 parts of lily, 10-20 parts of water-absorbing resin, 3-5 parts of disodium ethylene diamine tetraacetate.
Preparation method is as follows:3-5 parts of peppermint, 1-3 parts of borneol, 1-3 parts of rosemary, 1-3 parts of cloves, bergamot are weighed respectively 1-5 parts of essential oil, 1-3 parts of lily, it is possible to additionally incorporate 10-20 parts of water-absorbing resin, 3-5 parts of disodium ethylene diamine tetraacetate, be added after mixing 50-60 parts of pure water, stirs, and gelinite is made, is then coated on non-woven fabrics, then cuts into circular block or square block, system Into plaster.
The water-absorbing resin is polyacrylic based resin;Lining cloth layer is the base material of load medicament, can be non-woven fabrics or saturating Gas paper etc..
Application method:Open the package, take out patch, throw off release film, gelinite makes surrounding smooth patch just to navel Jail.
Embodiment two:A kind of halitosis navel paster, and example one are essentially identical, and difference is:
Medicament composition of layer:3 parts of peppermint, 1 part of borneol, 1 part of rosemary, 1 part of cloves, 1 part of Bergamot, 1 part of lily, suction 10 parts of water-resin, 3 parts of disodium ethylene diamine tetraacetate.Water-absorbing resin is polyvinyl alcohol resin, and lining cloth layer is air-permeable paper.
Embodiment three:A kind of halitosis navel paster, and example one are essentially identical, and difference is:
Medicament composition of layer:5 parts of peppermint, 3 parts of borneol, 3 parts of rosemary, 3 parts of cloves, 5 parts of Bergamot, 2 parts of lily, suction 20 parts of water-resin, 5 parts of disodium ethylene diamine tetraacetate.Water-absorbing resin is polyoxyethylene system resin.
Example IV:A kind of halitosis navel paster, and example one are essentially identical, and difference is:
Medicament composition of layer:4 parts of peppermint, 2 parts of borneol, 2 parts of rosemary, 2 parts of cloves, 3 parts of Bergamot, 3 parts of lily, suction 15 parts of water-resin, 4 parts of disodium ethylene diamine tetraacetate.

Claims (4)

1. a kind of halitosis navel paster, includes the lining cloth layer of upper strata off-style paper layer, middle medicament layer and bottom, it is characterized in that:It is described The composition of medicament layer is:3-5 parts of peppermint, 1-3 parts of borneol, 1-3 parts of rosemary, 1-3 parts of cloves, 1-5 parts of Bergamot, lily 1-3 parts, 10-20 parts of water-absorbing resin, 3-5 parts of disodium ethylene diamine tetraacetate.
2. halitosis navel paster according to claim 1, it is characterized in that:The water-absorbing resin is polyacrylic, polyethylene One kind in alcohol system, polyoxyethylene system resin.
3. the preparation method of the halitosis navel paster described in claim 1, it is characterized in that:3-5 parts of peppermint, borneol 1-3 are weighed respectively Part, 1-3 parts of rosemary, 1-3 parts of cloves, 1-5 parts of Bergamot, 1-3 parts of lily it is possible to additionally incorporate 10-20 parts of water-absorbing resin, second 3-5 parts of edetate disodium, adds 50-60 part of pure water, stirs after mixing, be coated on lining cloth layer, then cut it is blocking, Plaster is made.
4. the preparation method of halitosis navel paster according to claim 3, it is characterized in that:The water-absorbing resin is polyacrylic acid One kind in system, polyethenol series, polyoxyethylene system resin.
CN201410698466.3A 2014-11-28 2014-11-28 Halitosis navel paster and preparation method thereof Active CN104324214B (en)

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CN104324214B true CN104324214B (en) 2017-08-25

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