CN104323969A - Freckle-removing and inflammation-diminishing sunscreen cream and preparation method thereof - Google Patents

Freckle-removing and inflammation-diminishing sunscreen cream and preparation method thereof Download PDF

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CN104323969A
CN104323969A CN201410648125.5A CN201410648125A CN104323969A CN 104323969 A CN104323969 A CN 104323969A CN 201410648125 A CN201410648125 A CN 201410648125A CN 104323969 A CN104323969 A CN 104323969A
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sunscreen cream
inflammation
oil
skin
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CN104323969B (en
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孙淑萍
王凤各
花敬涵
柴智龙
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SHANGHAI DAERWEI BIOTECHNOLOGY RESEARCH AND DEVELOPMENT Co.,Ltd.
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Wannan Medical College
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Abstract

The invention discloses a freckle-removing and inflammation-diminishing sunscreen cream and a preparation method thereof. The formula of the freckle-removing and inflammation-diminishing sunscreen cream comprises such materials as shea butter, olive oil, coconut oil, general self-emulsifying compound emulsifier AC-402, all-powerful simple emulsifier G57, natural emulsifier GOC, emulsifier DOE, sodium acrylate SIMULGELEG, methyl silicone oil, mycose, glycerin, 25% triethanolamine solution, titanium dioxide, pearl powder, silkworm larva extract, safflower oil, cell activator, water-soluble vitamin E, polyvidone, distilled water, essence and efficient preservative Glydant. Compared with the prior art, the freckle-removing and inflammation-diminishing sunscreen cream is mild in nature and high in safety; the natural animal medicine silkworm larva is combined with other active ingredients to achieve the effects of whitening, blocking the sun, removing the pigment and keeping the skin elasticity; the coconut oil has anti-inflammation and anti-bacterial functions so that wounds can be healed quickly without inflammation or scar. The components of the formula supplement each other to effectively block the sun, realize after-sun repair, and whiten and nourish the skin, and therefore, the effects of blocking the sun, diminishing inflammation, removing freckles, maintaining beauty and eliminating the pigment can be achieved; as a result, the skin can be comprehensively improved from inside to outside.

Description

A kind of speckle dispelling antiphlogistic sunscreen cream and preparation method thereof
Technical field
The present invention relates to a kind of sunscreen cream, particularly a kind of speckle dispelling antiphlogistic sunscreen cream and preparation method thereof.
Background technology
Along with the appearance of Antarctic ozone hole, the earth has lacked the effective barrier of one deck, and the sun is increased the ultraviolet radiation of earth surface, produces destruction, affect the mankind and the organic normal existence of other biological to ecological environment.Especially hot summer, our skin can inevitably be subject to ultraviolet grievous injury, only relies on sun-screening umbrella to be inadequate.Protection skin has become something that we must face.Now, sunscreen cream just becomes anti-ultraviolet best skin-protection product.
Summary of the invention
For solving the problems of the technologies described above, the invention provides a kind of speckle dispelling antiphlogistic sunscreen cream, can not only be sun-proof, also there is the effect of speckle dispelling, skin care, elimination pigment.
Present invention also offers a kind of preparation method of speckle dispelling antiphlogistic sunscreen cream.
A kind of speckle dispelling antiphlogistic sunscreen cream provided by the invention, its raw material components and weight portion are:
Described Bombyx Batryticatus extracting solution is prepared by the following method:
Take Bombyx Batryticatus a certain amount of, soak 0.5-3h after pulverizing, decoct extraction 3 times in 90-100 DEG C of heating, add 8-12 times of water gaging the 1st time, extract 0.5-2h, add 6-10 times of water gaging 2nd time, extract 0.5-2h, add 4-8 times of water gaging the 3rd time, extract 0.5-1.5h, each use 3 layers of gauze filter, merging filtrate, and the volume concentration of filtrate is to 3-6 times of g/ml of Bombyx Batryticatus weight.
The preparation method of a kind of speckle dispelling antiphlogistic sunscreen cream provided by the invention, comprises the following steps:
A) take shea butter 20-60g, olive oil 40-140g, Oleum Cocois 5-40g, general-purpose self emulsifying mixed emulsifier AC-402 40-100g, and add all-round simple and easy emulsifying agent G57 10-60g, stir, as oil phase 1;
B) take naturally occurring emulsifying agent GOC 20-70g, methyl-silicone oil 20-80g, safflower oil 5-40g is as oil phase 2;
C) take titanium dioxide 5-60g, Margarita powder 5-40g, join in the distilled water of 100-400g, 60-80 DEG C of heating in water bath, heats while stirring, to be mixed evenly after, as mixture, stand-by;
D) trehalose 5-40g is taken, glycerol 5-60g, SIMULGEL EG 5-60g, 25% triethanolamine solution 0.5-4g, watermiscible vitamin E 5-40g, cell vitalizing agent 5-50g and emulsifying agent DOE 5-60g, add 100-400g distilled water, stir, as aqueous phase;
E) get polyvidone 30-100g, dissolve with distilled water 30-50g, obtain povidone solution, stand-by;
F) povidone solution is added in joined aqueous phase; Oil phase 1 and oil phase 2 mix homogeneously, obtain oil phase; Be that thread shape adds in oil phase subsequently by aqueous phase, form emulsion bases, then add step c) mixture prepared;
G) by Bombyx Batryticatus extracting solution 5-40g, add in above-mentioned mixed solution, and add essence 0.1-1.2g and efficient antiseptic Glydant 0.5-1.2g, mix homogeneously, speckle dispelling antiphlogistic sunscreen cream.
Various compositions in the present invention are as follows:
Bombyx Batryticatus is loaded with the effect of " go out black speck, make us complexion good " as far back as Shennong's Herbal.Protein contained by Bombyx Batryticatus has stimulates epithelium adipose gland, and the effect of modulability hormone secretion, thus has certain curative effect to the chloasma that estrogen dyssecretosis causes.Bombyx Batryticatus contains vitamin E, energy scavenging free radicals, the senile plaque that lipid peroxidation inhibition is formed.In addition, the active mercerising element contained by it can impel Skin Cell newborn, regulates sebum, improves skin microcirculation, can brighten sun-proof, eliminates pigmentation, keeps skin elasticity.The hydrolytic enzyme such as the protease that Bombyx Batryticatus contains, chitinase have digestion cutin, and decompose pigment, anti-cicatrix, goes acne, controls the effect of ecchymosis.
Oleum Cocois be quality splendid natural sun-prevention oil, there is antiphlogistic antibacterial function, general knife injury, scald, burn, mosquito to bite etc. dermatosis smear Oleum Cocois can healing of wound and not inflammation rapidly, and not scar, particularly to dermatosis such as diaper rash, rich and honour hands, dry moss, there is significant curative effect.
Shea butter is precious skin care item and is called as " gold of woman ".Shea butter can deep layer skin care, prevents xerosis cutis from ftractureing, and has good moisturizing, sun-proof, protection effect, can form protecting film in skin surface.
Olive oil, due to its splendid natural health, beauty functions, is described as " liquid golden " in west, " vegetable oil queen ".Olive oil can nourish skin, increases gloss and the elasticity of skin, removes fine wrinkles.
Super sun-proof Moisture factor trehalose is a kind of natural saccharide.Trehalose can protect epidermis cell membrane structure, activating cell effectively, and conditioning skin, makes skin health natural, flexible.
Titanium oxide is white, and stable chemical nature is nontoxic, and neutral, can absorb ultraviolet, its rate of absorbing UV is very high.
Cell vitalizing agent, promotes cell division, propagation, can the aging of delaying skin effectively.
Natural Vitamin E can prevent ultraviolet and contaminated air to the injury of skin, promotes the metabolism of skin, prevents pigmentation, improve skin elasticity, skin care.
In prescription, each composition complements each other, skin whitening, nourishes rough skin, reaches the effect of speckle dispelling, skin care, elimination pigment, thus the comprehensive improvement making skin obtain from inside to outside.
Compare with existing sunscreen cream, a kind of speckle dispelling antiphlogistic sunscreen cream provided by the invention has preferably sun-proof result, also adds Bombyx Batryticatus extracting solution, thus has the effect of speckle dispelling, skin care, elimination pigment.People, can also dispeling scar while use, and healing of wound, plays the effect of beauty treatment.Skin becomes moist full, and the colour of skin is obviously bright, and skin is smoothly pure, is full of gloss, all the time pale youth.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
The preparation of 1.1 Bombyx Batryticatus extracting solution
Take Bombyx Batryticatus 50g, soak 1.5h after pulverizing, decoct extraction 3 times in 95 DEG C of heating, add 8 times of water gagings the 1st time, extract 1.5h, add 6 times of water gagings 2nd time, extract 1h, add 4 times of water gagings the 3rd time, extract 0.5h, each use 3 layers of gauze filter, merging filtrate, and the volume concentration of filtrate is to 4 times of g/ml of Bombyx Batryticatus weight.
The preparation method of 1.2 1 kinds of speckle dispelling antiphlogistic sunscreen cream, comprises the following steps:
A) take shea butter 20g, olive oil 40g, Oleum Cocois 15g, general-purpose self emulsifying mixed emulsifier AC-402 40g, and add the all-round simple and easy emulsifying agent G57 of 20g, stir, as oil phase 1;
B) take naturally occurring emulsifying agent 20g, methyl-silicone oil 20g, safflower oil 10g is as oil phase 2.
C) take 10g titanium dioxide and 10g Margarita powder, join in the distilled water of 60g, 70 DEG C of heating in water bath, heat while stirring, to be mixed evenly after, as mixture, stand-by;
D) measure trehalose 10g, glycerol 10g, SIMULGEL EG 10g, 25% triethanolamine solution 1.5g, watermiscible vitamin E 15g, cell vitalizing agent 10g and emulsifying agent DOE 15g, adds 120g distilled water, stirs, as aqueous phase.
E) get 35g polyvidone, dissolve with 70g distilled water, obtain povidone solution, stand-by;
F) povidone solution is added in joined aqueous phase; Oil phase 1 and oil phase 2 mix homogeneously, obtain oil phase; Be that thread shape adds in oil phase subsequently by aqueous phase, form emulsion bases, then add previous joined mixture.
G) 5g Bombyx Batryticatus extracting solution is added in above-mentioned mixed solution, and adds 0.1g essence and 0.2g efficient antiseptic Glydant, mix homogeneously, leave standstill, this sunscreen cream.
Embodiment 2
The preparation of 2.1 Bombyx Batryticatus extracting solution
Take Bombyx Batryticatus 20g, soak 0.5h after pulverizing, decoct extraction 3 times in 90 DEG C of heating, add 8 times of water gagings the 1st time, extract 2h, add 6 times of water gagings 2nd time, extract 1h, add 6 times of water gagings the 3rd time, extract 0.5h, each use 3 layers of gauze filter, merging filtrate, and the volume concentration of filtrate is to 5 times of g/ml of Bombyx Batryticatus weight.
The preparation of 2.2 1 kinds of speckle dispelling antiphlogistic Bombyx Batryticatus sunscreen cream
A) take shea butter 60g, olive oil 110g, Oleum Cocois 45g, general-purpose self emulsifying mixed emulsifier AC-402 100g, and add the all-round simple and easy emulsifying agent of 50g, stir, as oil phase 1;
B) take naturally occurring emulsifying agent 70g, methyl-silicone oil 50g, safflower oil 30g is as oil phase 2.
C) take 40g titanium dioxide and 40g Margarita powder, join in the distilled water of 260g, 70 DEG C of heating in water bath, heat while stirring, to be mixed evenly after, as mixture, stand-by;
D) measure trehalose 40g, glycerol 50g, SIMULGEL EG 40g, 25% triethanolamine solution 4g, watermiscible vitamin E 40g, cell vitalizing agent 35g and emulsifying agent DOE 60g, adds 400g distilled water, stirs, as aqueous phase.
E) get 100g polyvidone, dissolve with 200g distilled water, obtain povidone solution, stand-by;
F) povidone solution is added in joined aqueous phase; Oil phase 1 and oil phase 2 mix homogeneously, obtain oil phase; Be that thread shape adds in oil phase subsequently by aqueous phase, form emulsion bases, then add previous joined mixture.
G) 15g Bombyx Batryticatus extracting solution is added in above-mentioned mixed solution, and adds 0.3g essence and 0.5g efficient antiseptic Glydant, mix homogeneously, leave standstill, this sunscreen cream.
Embodiment 3
The physical and chemical index of embodiment 1, example 2 is as follows:
3.1 character
This product is that viscosity is suitable for, evenly fine and smooth, the milky sunscreen cream that stretchability is good.
3.2pH value checks
Dip a small amount of sunscreen cream with the pH reagent paper of moistening, pH is 7.0-7.3, alkalescence.
3.3 caloric test
Sunscreen cream is packaged in transparence cosmetic bottle, observes without lamination in the refrigerator cold-storages about a week of 4 DEG C.24h in the calorstat of 55 DEG C, solution is without the phenomenon such as layering, emulsifying is spoiled.
3.4 centrifugal test
Sunscreen cream is packaged in 3000r/min in tool plug test tube, centrifugal 20min, without lamination.
3.5 irritation tests, anaphylaxis are tested
White mice back cuts off hair, smears the sunscreen cream prepared by embodiment 1,2 respectively in cutting plucked position, and is not coated with position and compares, and result does not have zest and anaphylaxis.
Example 1 gram is applied on volunteer (15-45 year, 80 people) arm, observes after spending 30 minutes, all do not occur rubescent, play rash phenomenon.
3.6 room temperatures place experiment
Embodiment 1,2 made sunscreen cream are placed in bottle for cosmetics, and room temperature leaves standstill investigation 6 months, without lamination, with after feel unchanged, abnormal smells from the patient is unchanged, without denaturalization phenomenon.
3.7 whitening effect
Choose volunteer (this school classmate), by obtained sunscreen cream for volunteer's arm, find that whitening effect is better, volunteers generally feel smooth comfortable, and feel is better.After a period of time on probation, find that skin has good whitening effect, whiteness of skin, finer and smoother, moistening effect is also good.
Embodiment 4
This sunscreen cream resultant effect is investigated:
Below utilize on probation feel to carry out Evaluation operation example 1, effect of sunscreen cream that example 2 produces.Adopt public-opinion poll point system, choose 50 18-22 year age bracket classmate as object on probation, be divided into arbitrarily two groups, improve skin with the sunscreen cream of embodiment 1,2 preparation respectively.Use twice weekly, service time is two months.Every result of use total score is 5 points: 5 be divided into best result, represents very well, very satisfaction; 4 are divided into better; 3 are divided into and can accept; Less than 3 points is bad, can not accept.Be below every average: the results are shown in Table 1
Table 1 resultant effect is investigated
Result of use The every average of embodiment 1 The every average of embodiment 2
Speckle dispelling 4.8 4.9
Alimentary 4.7 4.8
Whitening 5 5
Prosthetic 4.8 4.7
Anti-inflammatory 4.0 3.9
In sum, made this sunscreen cream of the present invention has good whitening, prosthetic, feels smooth comfortable, have the effects such as speckle dispelling, whitening, reparation with rear skin during use.

Claims (3)

1. a speckle dispelling antiphlogistic sunscreen cream, is characterized in that, its raw material components and weight portion are:
2. speckle dispelling antiphlogistic sunscreen cream according to claim 1, is characterized in that, described Bombyx Batryticatus extracting solution is prepared by the following method: take Bombyx Batryticatus a certain amount of, soak 0.5-3h after pulverizing, decoct extraction 3 times in 90-100 DEG C of heating, add 8 times of water gagings the 1st time, extract 2h, add 6 times of water gagings 2nd time, extract 1h, add 4 times of water gagings the 3rd time, extract 0.5h, each use 3 layers of gauze filter, merging filtrate, and the volume concentration of filtrate is to 4 times of g/ml of Bombyx Batryticatus weight.
3. a preparation method for the speckle dispelling antiphlogistic sunscreen cream described in claim 1 or 2, it is characterized in that, described preparation method comprises the following steps:
A) take shea butter 20-60g, olive oil 40-140g, Oleum Cocois 5-40g, general-purpose self emulsifying mixed emulsifier AC-402 40-100g, and add all-round simple and easy emulsifying agent G57 10-60g, stir, as oil phase 1;
B) take naturally occurring emulsifying agent GOC 20-70g, methyl-silicone oil 20-80g, safflower oil 5-40g is as oil phase 2;
C) take titanium dioxide 5-60g, Margarita powder 5-40g, join in the distilled water of 100-400g, 60-80 DEG C of heating in water bath, heats while stirring, to be mixed evenly after, as mixture, stand-by;
D) trehalose 5-40g is taken, glycerol 5-60g, SIMULGEL EG 5-60g, 25% triethanolamine solution 0.5-4g, watermiscible vitamin E 5-40g, cell vitalizing agent 5-50g and emulsifying agent DOE 5-60g, add 100-400g distilled water, stir, as aqueous phase;
E) get polyvidone 30-100g, dissolve with distilled water 30-50g, obtain povidone solution, stand-by;
F) povidone solution is added in joined aqueous phase; Oil phase 1 and oil phase 2 mix homogeneously, obtain oil phase; Be that thread shape adds in oil phase subsequently by aqueous phase, form emulsion bases, then add step c) mixture prepared;
G) by Bombyx Batryticatus extracting solution 5-40g, add in above-mentioned mixed solution, and add essence 0.1-1.2g and efficient antiseptic Glydant 0.5-1.2g, mix homogeneously, speckle dispelling antiphlogistic sunscreen cream.
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CN105943474A (en) * 2016-07-06 2016-09-21 广东工业大学 Composition, as well as preparation method and application thereof
CN106860038A (en) * 2017-02-23 2017-06-20 长沙协浩吉生物工程有限公司 A kind of compound method of ferment nti-freckle suncream
CN106860102A (en) * 2017-02-23 2017-06-20 长沙协浩吉生物工程有限公司 A kind of compound method of ferment nti-freckle suncream
CN106901995A (en) * 2017-02-23 2017-06-30 长沙协浩吉生物工程有限公司 A kind of compound method of ferment nti-freckle suncream
CN108938504A (en) * 2018-09-30 2018-12-07 广西秀美壮乡能源环保有限公司 A kind of Skin whitening care cosmetics and preparation method thereof
CN109288775A (en) * 2018-11-26 2019-02-01 纪翠苗 A kind of alkalinity formula of sun screen

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CN105943474A (en) * 2016-07-06 2016-09-21 广东工业大学 Composition, as well as preparation method and application thereof
CN106860038A (en) * 2017-02-23 2017-06-20 长沙协浩吉生物工程有限公司 A kind of compound method of ferment nti-freckle suncream
CN106860102A (en) * 2017-02-23 2017-06-20 长沙协浩吉生物工程有限公司 A kind of compound method of ferment nti-freckle suncream
CN106901995A (en) * 2017-02-23 2017-06-30 长沙协浩吉生物工程有限公司 A kind of compound method of ferment nti-freckle suncream
CN108938504A (en) * 2018-09-30 2018-12-07 广西秀美壮乡能源环保有限公司 A kind of Skin whitening care cosmetics and preparation method thereof
CN108938504B (en) * 2018-09-30 2021-05-07 台州中知英健机械自动化有限公司 Whitening skin care product and preparation method thereof
CN109288775A (en) * 2018-11-26 2019-02-01 纪翠苗 A kind of alkalinity formula of sun screen

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