CN104307060A - X-ray blood irradiator - Google Patents
X-ray blood irradiator Download PDFInfo
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- CN104307060A CN104307060A CN201410563079.9A CN201410563079A CN104307060A CN 104307060 A CN104307060 A CN 104307060A CN 201410563079 A CN201410563079 A CN 201410563079A CN 104307060 A CN104307060 A CN 104307060A
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- blood irradiator
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0281—Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
The invention discloses an X-ray blood irradiator comprising an X-ray unit, a rotating carrier disc, an X-ray shielding case, an air-water cooler, a human-machine interface and an industrial personal computer. The X-ray unit comprises a metal ceramic X-ray tube, a high tension generator and a high-tension cable; the X-ray tube and the rotating carrier disc are disposed inside an irradiation chamber enclosed by the X-ray shielding case. A blood container is mounted on the rotating carrier disc. The rotating carrier disc is driven to rotate by a motor. A filter is added to a path of the X-ray emitted by the X-ray tube. Instead of radioisotopes, the X-ray unit is used as an irradiation source; the irradiator needs highly fewer shielding materials than a gamma-ray irradiator; the irradiator is small and portable and generates X-ray only when required; safety hazards are eliminated; the problem of disposal of nuclear waste is also avoided.
Description
Technical field
The invention belongs to and belong to armarium, for there is immunocompetent lymphocyte in deactivation blood, being specifically related to X-ray blood irradiator.
Background technology
The radiation treatment technology of blood (or blood products) is widely used after the seventies, especially to the patient of bone marrow transplant patient, leukemia people or immunologic hypofunction.At present, major part blood irradiator adopts radioactive isotope power supply (as conventional caesium-137 and cobalt-60) to produce gamma-rays, by there is immunocompetent lymphocyte in control roentgendosis optionally deactivation blood, the generation of prevention transfusion-associated graft versus host disease.The energy of γ ray that isotopic source sends very high (energy of γ ray of caesium-137 is that 662keV, Co-60 release 2 gamma-rays, and its energy is respectively 1.17MeV and 1.33MeV), needs a large amount of shieldings and high-level protection; The continual transmitting gamma-rays of isotopic source, uses and there is certain potential safety hazard in blood station and hospital environment; Isotopic source can decay, and needs periodic calibration, and therefore exposure time also needs progressively to extend; The problem that isotope waste material is difficult to dispose also is there is after equipment is retired.
Summary of the invention
The object of the invention is to overcome prior art Problems existing, provide X-ray blood irradiator, the X-ray utilizing X-ray apparatus to send carrys out radiation blood, has immunocompetent lymphocyte in deactivation blood.The highest energy of X-ray is 160keV, and required shielding material comparatively gamma-ray irradiation instrument significantly reduces, equipment small volume and less weight; Adopt X-ray apparatus to replace radiosiotope as irradiation bomb, X-ray only produces when needed, eliminates potential safety hazard, also there is not nuclear waste disposal problem.
For realizing above-mentioned technical purpose, reach above-mentioned technique effect, the present invention is achieved through the following technical solutions:
X-ray blood irradiator, comprise X-ray apparatus, rotate carrying disk, X-ray radome, edema due to wind pathogen cooler, human-computer interaction interface and industrial computer, described X-ray apparatus comprises metal-ceramic X-ray tube, high tension generator, high tension cable, described X-ray tube and rotate carrying disk and be arranged in the radiation chamber that X-ray radome surrounds, described rotation carrying disk is provided with blood vessel, by rotating carrying disk by power transmission to blood vessel, drive blood vessel together stable rotation simultaneously, rotate carrying disk and drive rotation by motor, the X-ray path that described X-ray tube sends is provided with added filtration device, ensure that the X-ray exported has suitable energy and penetration power.
Further, described X-ray radome is enough thick sheet lead or inner housing of filling shielding material, leaks, guarantee the safety of operator to reduce external radiation.
Further, described rotation carrying disk and the connected mode between motor are direct-connected or are indirectly connected by gear reduction unit, and described motor is the one among motor or servomotor, by controlling the rotating speed of motor, control the rotating speed rotating carrying disk.
Further, the X-ray beam that described X-ray tube sends is cone beam, and the angle of departure is not less than 40 °, is specifically advisable can all cover blood vessel.
Further, bottom and the top of described X-ray radome are respectively equipped with air inlet and air outlet, and air inlet is provided with drainage screen, and air outlet place is provided with fan.
Further, be provided with 4 bottom this X-ray blood irradiator and can lock castor.
Further, described human-computer interaction interface is made up of touch screen or display and keyboard.
Further, described industrial computer controls the start and stop of high tension generator, optimum configurations, the direction of rotation of motor and rotary speed, the monitoring of radiation chamber internal temperature, and wherein optimum configurations comprises tube voltage, tube current, irradiation dose.
Further, described high tension generator realizes by the tube voltage of fine adjustment X-ray tube and tube current the controllable precise that x-ray dose exports.
The invention has the beneficial effects as follows:
1, X-ray blood irradiator of the present invention, simple and reasonable, and barrier propterty is good, easy to install, the X-ray utilizing X-ray tube to send carries out irradiation to blood, by rotating blood vessel, the uniformity of irradiation dose can be realized, meet the requirement of blood irradiation.
2, adopt fan to cool radiation chamber, avoid blood heat too high and cause addling.
3, realize roentgendosis by fine adjustment tube voltage and tube current to control, optionally in deactivation blood, there is immunocompetent lymphocyte, the generation of prevention transfusion-associated graft versus host disease.
Accompanying drawing explanation
Fig. 1 is the structural representation of the embodiment of the present invention 1;
Fig. 2 is the structural representation of the embodiment of the present invention 2;
Fig. 3 is that blood vessel rotates schematic diagram;
Fig. 4 is radiation chamber cooling schematic diagram.
Number in the figure illustrates: 1, X-ray tube, 2, X-ray radome, 3, rotate carrying disk, 4, edema due to wind pathogen cooler, 5, high tension generator, 6, high tension cable, 7, cooling tube, 8, touch screen, 9, industrial computer, 10, power-supply filter, 11, attaching plug, 12, castor, 13, blood vessel, 14, fan, 15, drainage screen.
Detailed description of the invention
Below with reference to the accompanying drawings and in conjunction with the embodiments, describe the present invention in detail.
As shown in Figure 1, X-ray blood irradiator of the present invention mainly comprises X-ray tube 1, high tension generator 5, high tension cable 6, rotates carrying disk 3, X-ray radome 2, edema due to wind pathogen cooler 4, industrial computer 9, touch screen 8, power-supply filter 10 and attaching plug 11, X-ray tube 1 and rotation carrying disk 3 are positioned at the radiation chamber that X-ray radome 2 surrounds, X-ray radome 2 is made up of enough thick sheet lead, leak to reduce external radiation, guarantee the safety of operator.
Rotate carrying disk 3 to be driven by rotating shaft, rotating shaft drives by motor shaft, or is indirectly driven by motor shaft and travelling gear, by controlling the rotating speed of motor, controls the rotating speed rotating carrying disk.As shown in Figure 3, the X-ray beam that X-ray tube 1 sends is cone-beam, and the angle of departure is not less than 40 °, and blood vessel 13 is generally cylindrical shape, and X-ray beam all must can cover blood vessel.The X-ray that X-ray tube 1 sends is filtered through inherent filtration and added filtration device, can ensure that the X-ray exported has suitable energy and penetration power.
Be equipped with 4 can lock universal caster wheel 12 bottom X-ray blood irradiator, easy to install and use.
In order to ensure by the concordance of radiation blood absorbed dose, the number of turns that blood vessel 13 rotates in exposure time section must be integer, rotational angular velocity should adjust according to the length of exposure time, feasible way first allows blood vessel 13 rotate, reach X-ray tube 1 after setting value until rotary speed just to start to send X-ray, open appliance doors, the blood vessel 13 that packed blood is housed is placed into and rotates on carrying disk 3, closing device door, rotating carrying disk 3 drives blood vessel 13 to rotate, industrial computer 9 controls high tension generator 5 output HIGH voltage by serial ports or CAN, X-ray tube 1 produces X-ray and starts irradiation, X-ray tube 1 maximum tube voltage is 160kV, the X-ray highest energy sent is 160keV.After arriving the irradiation dose of setting, high tension generator 5 quits work, and X-ray tube 1 also stops sending X-ray, and rotate carrying disk 3 and stop the rotation, irradiation terminates.Open appliance doors, take out blood vessel 13.
In X-ray generating process, X-ray tube 1 can produce amount of heat, utilizes the inner integrated edema due to wind pathogen cooler 4 pairs of X-ray tubes 1 of blood irradiator effectively to dispel the heat, does not need external water pipe.Liquid coolant is the mixed liquor of water or water and antifreezing agent, the water inlet of X-ray tube 1 is connected by cooling tube 7 with the water inlet of cooler 4 with the outlet of the outlet of cooler 4, X-ray tube 1, liquid coolant circulates between ray tube 1 and cooler 4, after liquid coolant cooling X-ray tube 1, by again being cooled during air cooled heat exchanger.
In irradiation process, X-ray tube 1 is a thermal source, radiation chamber inside and blood bag temperature may be caused to rise, if the too high blood of blood bag temperature can break down, need to take cooling measure.As shown in Figure 4, in X-ray radome 2 structure, design air inlet and air outlet, adopt fan 14 to dispel the heat, and enough shieldings are provided.
High tension generator 5 can the tube voltage of fine adjustment X-ray tube 1 and tube current, thus realizes x-ray dose and export controllable precise.Irradiation instrument calculates exposure time automatically according to the irradiation dose of setting, is controlled startup and the stopping of high tension generator 5 by industrial computer 9.
The control system of blood irradiator for core with industrial computer 9, is responsible for the control, the monitoring of radiation chamber internal temperature etc. of high tension generator 5, is realized man-machine interaction by touch screen 8.
Fig. 2 is another kind of embodiment, is X-ray tube 1 and rotates the mounting means of carrying disk 3 by vertically changing level into the difference of embodiment 1.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (9)
1.X ray blood irradiator, comprise X-ray apparatus, rotate carrying disk (3), X-ray radome (2), edema due to wind pathogen cooler (4), human-computer interaction interface and industrial computer (9), it is characterized in that, described X-ray apparatus comprises metal-ceramic X-ray tube (1), high tension generator (5), high tension cable (6), described X-ray tube (1) and rotate carrying disk (3) and be arranged in the radiation chamber that X-ray radome (2) surrounds, described rotation carrying disk (3) is provided with blood vessel (13), rotate carrying disk (3) and drive rotation by motor, the X-ray path that described X-ray tube (1) sends is provided with added filtration device.
2. X-ray blood irradiator according to claim 1, is characterized in that, described X-ray radome (2) is enough thick sheet lead or inner housing of filling shielding material.
3. X-ray blood irradiator according to claim 1, is characterized in that, described rotation carrying disk (3) is direct-connected with the connected mode between motor or is indirectly connected by gear reduction unit, and described motor is the one among motor or servomotor.
4. X-ray blood irradiator according to claim 1, is characterized in that, the X-ray beam that described X-ray tube (1) sends is cone beam, and the angle of departure is not less than 40 °, is advisable all can cover blood vessel (13).
5. X-ray blood irradiator according to claim 1 and 2, is characterized in that, bottom and the top of described X-ray radome (2) are respectively equipped with air inlet and air outlet, and air inlet is provided with drainage screen (15), and air outlet place is provided with fan (14).
6. X-ray blood irradiator according to claim 1, is characterized in that, is provided with 4 and can locks castor (12) bottom this X-ray blood irradiator.
7. X-ray blood irradiator according to claim 1, is characterized in that, described human-computer interaction interface is made up of touch screen or display and keyboard.
8. X-ray blood irradiator according to claim 1, is characterized in that, described industrial computer (9) controls the start and stop of high tension generator (5), optimum configurations, the direction of rotation of motor and rotary speed, the monitoring of radiation chamber internal temperature.
9. the X-ray blood irradiator according to claim 1 or 8, is characterized in that, described high tension generator (5) realizes by the tube voltage of fine adjustment X-ray tube (1) and tube current the controllable precise that x-ray dose exports.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410563079.9A CN104307060B (en) | 2014-10-22 | X-ray blood irradiator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410563079.9A CN104307060B (en) | 2014-10-22 | X-ray blood irradiator |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104307060A true CN104307060A (en) | 2015-01-28 |
| CN104307060B CN104307060B (en) | 2017-01-04 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104984422A (en) * | 2015-07-24 | 2015-10-21 | 江苏摩科特医疗科技有限公司 | Double-X-ray-source blood irradiator |
| CN106620910A (en) * | 2016-12-23 | 2017-05-10 | 珠海丽珠试剂股份有限公司 | Uniform single X-ray source blood irradiator |
| CN116364327A (en) * | 2023-03-10 | 2023-06-30 | 中国科学院苏州生物医学工程技术研究所 | Design and installation method of X-ray filter of blood irradiation instrument |
| RU227361U1 (en) * | 2023-09-15 | 2024-07-17 | Георгий Борисович Шарков | Blood irradiation device |
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| EP0658355A2 (en) * | 1993-12-14 | 1995-06-21 | Therakos, Inc. | Ultraviolet light chamber |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104984422A (en) * | 2015-07-24 | 2015-10-21 | 江苏摩科特医疗科技有限公司 | Double-X-ray-source blood irradiator |
| CN106620910A (en) * | 2016-12-23 | 2017-05-10 | 珠海丽珠试剂股份有限公司 | Uniform single X-ray source blood irradiator |
| CN116364327A (en) * | 2023-03-10 | 2023-06-30 | 中国科学院苏州生物医学工程技术研究所 | Design and installation method of X-ray filter of blood irradiation instrument |
| RU227361U1 (en) * | 2023-09-15 | 2024-07-17 | Георгий Борисович Шарков | Blood irradiation device |
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